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ENCODE cell lines, expression (Ernst 2011)

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Results for TBX15_MGA

Z-value: 1.27

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Transcription factors associated with TBX15_MGA

Gene Symbol Gene ID Gene Info
TBX15
ENSG00000092607.9 TBX15
MGA
ENSG00000174197.12 MGA

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MGAhg19_v2_chr15_+_41952591_419526720.155.7e-01Click!

Activity profile of TBX15_MGA motif

Sorted Z-values of TBX15_MGA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX15_MGA

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr20_-_22565101 4.79 ENST00000419308.2
 FOXA2
 forkhead box A2
chr14_+_95078714 4.77 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
 SERPINA3
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr9_-_75567962 3.86 ENST00000297785.3
ENST00000376939.1
 ALDH1A1
 aldehyde dehydrogenase 1 family, member A1
chr2_+_228678550 3.65 ENST00000409189.3
ENST00000358813.4
 CCL20
 chemokine (C-C motif) ligand 20
chrX_-_133119476 3.31 ENST00000543339.1
 GPC3
 glypican 3
chr2_-_39664405 3.24 ENST00000341681.5
ENST00000263881.3
 MAP4K3
 mitogen-activated protein kinase kinase kinase kinase 3
chr12_+_56473939 2.96 ENST00000450146.2
 ERBB3
 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr6_+_7541808 2.81 ENST00000379802.3
 DSP
 desmoplakin
chr11_+_73358594 2.64 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
 PLEKHB1
 pleckstrin homology domain containing, family B (evectins) member 1
chr17_-_1619535 2.58 ENST00000573075.1
ENST00000574306.1
 MIR22HG
 MIR22 host gene (non-protein coding)
chr2_+_62932779 2.48 ENST00000427809.1
ENST00000405482.1
ENST00000431489.1
 EHBP1
 EH domain binding protein 1
chr11_+_46402297 2.43 ENST00000405308.2
 MDK
 midkine (neurite growth-promoting factor 2)
chr2_+_62933001 2.43 ENST00000263991.5
ENST00000354487.3
 EHBP1
 EH domain binding protein 1
chr6_+_7541845 2.31 ENST00000418664.2
 DSP
 desmoplakin
chr12_+_69742121 2.29 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
 LYZ
 lysozyme
chr17_-_1619491 2.27 ENST00000570416.1
ENST00000575626.1
ENST00000610106.1
ENST00000608198.1
ENST00000609442.1
ENST00000334146.3
ENST00000576489.1
ENST00000608245.1
ENST00000609398.1
ENST00000608913.1
ENST00000574016.1
ENST00000571091.1
ENST00000573127.1
ENST00000609990.1
ENST00000576749.1
 MIR22HG
 MIR22 host gene (non-protein coding)
chr3_-_120170052 2.19 ENST00000295633.3
 FSTL1
 follistatin-like 1
chrX_-_99891796 2.15 ENST00000373020.4
 TSPAN6
 tetraspanin 6
chr20_+_34680620 2.03 ENST00000430276.1
ENST00000373950.2
ENST00000452261.1
 EPB41L1
 erythrocyte membrane protein band 4.1-like 1
chr8_-_27457494 2.03 ENST00000521770.1
 CLU
 clusterin
chr4_-_186732048 1.96 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
 SORBS2
 sorbin and SH3 domain containing 2
chr11_+_86511569 1.89 ENST00000441050.1
 PRSS23
 protease, serine, 23
chr3_-_49459865 1.79 ENST00000427987.1
 AMT
 aminomethyltransferase
chr11_-_27494309 1.79 ENST00000389858.4
 LGR4
 leucine-rich repeat containing G protein-coupled receptor 4
chr1_-_161193349 1.78 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
 APOA2
 apolipoprotein A-II
chr3_+_186330712 1.78 ENST00000411641.2
ENST00000273784.5
 AHSG
 alpha-2-HS-glycoprotein
chr11_-_27494279 1.76 ENST00000379214.4
 LGR4
 leucine-rich repeat containing G protein-coupled receptor 4
chr10_+_94451574 1.74 ENST00000492654.2
 HHEX
 hematopoietically expressed homeobox
chr5_-_172756506 1.71 ENST00000265087.4
 STC2
 stanniocalcin 2
chr3_-_99833333 1.64 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
 FILIP1L
 filamin A interacting protein 1-like
chr1_-_12677714 1.60 ENST00000376223.2
 DHRS3
 dehydrogenase/reductase (SDR family) member 3
chr10_-_15413035 1.60 ENST00000378116.4
ENST00000455654.1
 FAM171A1
 family with sequence similarity 171, member A1
chr3_-_49459878 1.60 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
 AMT
 aminomethyltransferase
chr2_-_26101374 1.53 ENST00000435504.4
 ASXL2
 additional sex combs like 2 (Drosophila)
chr2_-_175869936 1.50 ENST00000409900.3
 CHN1
 chimerin 1
chr2_-_26101314 1.50 ENST00000336112.4
ENST00000272341.4
 ASXL2
 additional sex combs like 2 (Drosophila)
chr2_+_102508955 1.49 ENST00000414004.2
 FLJ20373
 FLJ20373
chrX_+_105937068 1.47 ENST00000324342.3
 RNF128
 ring finger protein 128, E3 ubiquitin protein ligase
chr6_-_31620149 1.45 ENST00000435080.1
ENST00000375976.4
ENST00000441054.1
 BAG6
 BCL2-associated athanogene 6
chr2_-_175870085 1.39 ENST00000409156.3
 CHN1
 chimerin 1
chr6_+_31620191 1.36 ENST00000375918.2
ENST00000375920.4
 APOM
 apolipoprotein M
chr10_-_92681033 1.27 ENST00000371697.3
 ANKRD1
 ankyrin repeat domain 1 (cardiac muscle)
chr2_+_11696464 1.26 ENST00000234142.5
 GREB1
 growth regulation by estrogen in breast cancer 1
chrX_+_70443050 1.25 ENST00000361726.6
 GJB1
 gap junction protein, beta 1, 32kDa
chr1_-_226374373 1.24 ENST00000366812.5
 ACBD3
 acyl-CoA binding domain containing 3
chr17_+_57784826 1.20 ENST00000262291.4
 VMP1
 vacuole membrane protein 1
chr12_-_56120838 1.17 ENST00000548160.1
 CD63
 CD63 molecule
chr4_-_102268484 1.16 ENST00000394853.4
 PPP3CA
 protein phosphatase 3, catalytic subunit, alpha isozyme
chr3_-_66551397 1.13 ENST00000383703.3
 LRIG1
 leucine-rich repeats and immunoglobulin-like domains 1
chr11_+_46402482 1.13 ENST00000441869.1
 MDK
 midkine (neurite growth-promoting factor 2)
chr8_+_123793633 1.12 ENST00000314393.4
 ZHX2
 zinc fingers and homeoboxes 2
chr2_+_219283815 1.11 ENST00000248444.5
ENST00000454069.1
ENST00000392114.2
 VIL1
 villin 1
chr1_-_169555779 1.08 ENST00000367797.3
ENST00000367796.3
 F5
 coagulation factor V (proaccelerin, labile factor)
chr3_-_66551351 1.08 ENST00000273261.3
 LRIG1
 leucine-rich repeats and immunoglobulin-like domains 1
chr1_+_155099927 1.05 ENST00000368407.3
 EFNA1
 ephrin-A1
chr1_+_155100342 1.05 ENST00000368406.2
 EFNA1
 ephrin-A1
chr11_-_6502580 1.04 ENST00000423813.2
ENST00000396777.3
 ARFIP2
 ADP-ribosylation factor interacting protein 2
chr1_+_169077172 1.03 ENST00000499679.3
 ATP1B1
 ATPase, Na+/K+ transporting, beta 1 polypeptide
chr9_+_75766652 1.00 ENST00000257497.6
 ANXA1
 annexin A1
chr20_-_50385138 1.00 ENST00000338821.5
 ATP9A
 ATPase, class II, type 9A
chr3_+_142315225 0.98 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
 PLS1
 plastin 1
chr4_-_186456766 0.98 ENST00000284771.6
 PDLIM3
 PDZ and LIM domain 3
chr4_-_186456652 0.96 ENST00000284767.5
ENST00000284770.5
 PDLIM3
 PDZ and LIM domain 3
chr11_-_115375107 0.95 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
 CADM1
 cell adhesion molecule 1
chr11_+_61447845 0.93 ENST00000257215.5
 DAGLA
 diacylglycerol lipase, alpha
chrX_-_48693955 0.92 ENST00000218230.5
 PCSK1N
 proprotein convertase subtilisin/kexin type 1 inhibitor
chr21_+_30502806 0.92 ENST00000399928.1
ENST00000399926.1
 MAP3K7CL
 MAP3K7 C-terminal like
chr2_+_128177458 0.90 ENST00000409048.1
ENST00000422777.3
 PROC
 protein C (inactivator of coagulation factors Va and VIIIa)
chr20_+_11898507 0.90 ENST00000378226.2
 BTBD3
 BTB (POZ) domain containing 3
chr3_-_49722523 0.88 ENST00000448220.1
 MST1
 macrophage stimulating 1 (hepatocyte growth factor-like)
chr17_+_57784997 0.87 ENST00000537567.1
ENST00000539763.1
ENST00000587945.1
ENST00000536180.1
ENST00000589823.2
ENST00000592106.1
ENST00000591315.1
ENST00000545362.1
 VMP1
 vacuole membrane protein 1
chr17_+_4675175 0.84 ENST00000270560.3
 TM4SF5
 transmembrane 4 L six family member 5
chr11_-_6502534 0.83 ENST00000254584.2
ENST00000525235.1
ENST00000445086.2
 ARFIP2
 ADP-ribosylation factor interacting protein 2
chr12_+_104324112 0.83 ENST00000299767.5
 HSP90B1
 heat shock protein 90kDa beta (Grp94), member 1
chr17_-_77924627 0.81 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
 TBC1D16
 TBC1 domain family, member 16
chr16_-_28550320 0.81 ENST00000395641.2
 NUPR1
 nuclear protein, transcriptional regulator, 1
chr2_-_183903133 0.80 ENST00000361354.4
 NCKAP1
 NCK-associated protein 1
chr7_-_76255444 0.78 ENST00000454397.1
 POMZP3
 POM121 and ZP3 fusion
chr14_+_55034330 0.78 ENST00000251091.5
 SAMD4A
 sterile alpha motif domain containing 4A
chr1_+_151584544 0.77 ENST00000458013.2
ENST00000368843.3
 SNX27
 sorting nexin family member 27
chr17_+_35849937 0.77 ENST00000394389.4
 DUSP14
 dual specificity phosphatase 14
chr1_-_19229248 0.77 ENST00000375341.3
 ALDH4A1
 aldehyde dehydrogenase 4 family, member A1
chr4_-_102268628 0.75 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
 PPP3CA
 protein phosphatase 3, catalytic subunit, alpha isozyme
chr6_+_121756809 0.74 ENST00000282561.3
 GJA1
 gap junction protein, alpha 1, 43kDa
chrX_+_135230712 0.74 ENST00000535737.1
 FHL1
 four and a half LIM domains 1
chr14_+_32546274 0.74 ENST00000396582.2
 ARHGAP5
 Rho GTPase activating protein 5
chr1_-_19229014 0.74 ENST00000538839.1
ENST00000290597.5
 ALDH4A1
 aldehyde dehydrogenase 4 family, member A1
chr9_+_124048864 0.74 ENST00000545652.1
 GSN
 gelsolin
chrX_-_131623874 0.73 ENST00000436215.1
 MBNL3
 muscleblind-like splicing regulator 3
chr3_+_38017264 0.73 ENST00000436654.1
 CTDSPL
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr20_+_4152356 0.72 ENST00000379460.2
 SMOX
 spermine oxidase
chr16_+_2588012 0.71 ENST00000354836.5
ENST00000389224.3
 PDPK1
 3-phosphoinositide dependent protein kinase-1
chr17_-_57784755 0.71 ENST00000537860.1
ENST00000393038.2
ENST00000409433.2
 PTRH2
 peptidyl-tRNA hydrolase 2
chr12_-_8815299 0.69 ENST00000535336.1
 MFAP5
 microfibrillar associated protein 5
chrX_-_10851762 0.68 ENST00000380785.1
ENST00000380787.1
 MID1
 midline 1 (Opitz/BBB syndrome)
chr12_-_8815215 0.68 ENST00000544889.1
ENST00000543369.1
 MFAP5
 microfibrillar associated protein 5
chr6_-_160166218 0.68 ENST00000537657.1
 SOD2
 superoxide dismutase 2, mitochondrial
chr7_-_27135591 0.68 ENST00000343060.4
ENST00000355633.5
 HOXA1
 homeobox A1
chr11_+_114310102 0.67 ENST00000265881.5
 REXO2
 RNA exonuclease 2
chr1_-_205290865 0.67 ENST00000367157.3
 NUAK2
 NUAK family, SNF1-like kinase, 2
chrX_-_131623982 0.66 ENST00000370844.1
 MBNL3
 muscleblind-like splicing regulator 3
chr18_-_30050395 0.66 ENST00000269209.6
ENST00000399218.4
 GAREM
 GRB2 associated, regulator of MAPK1
chr17_-_46682321 0.63 ENST00000225648.3
ENST00000484302.2
 HOXB6
 homeobox B6
chr12_-_56120865 0.62 ENST00000548898.1
ENST00000552067.1
 CD63
 CD63 molecule
chr6_-_86099898 0.62 ENST00000455071.1
 RP11-30P6.6
 RP11-30P6.6
chr19_-_48894104 0.62 ENST00000597017.1
 KDELR1
 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr3_+_52811596 0.61 ENST00000542827.1
ENST00000273283.2
 ITIH1
 inter-alpha-trypsin inhibitor heavy chain 1
chr11_+_114310237 0.59 ENST00000539119.1
 REXO2
 RNA exonuclease 2
chr2_-_136288113 0.59 ENST00000401392.1
 ZRANB3
 zinc finger, RAN-binding domain containing 3
chr9_-_73029540 0.58 ENST00000377126.2
 KLF9
 Kruppel-like factor 9
chr19_-_39390350 0.58 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
 SIRT2
 sirtuin 2
chr17_-_79869004 0.58 ENST00000573927.1
ENST00000331285.3
ENST00000572157.1
 PCYT2
 phosphate cytidylyltransferase 2, ethanolamine
chr14_+_55034599 0.58 ENST00000392067.3
ENST00000357634.3
 SAMD4A
 sterile alpha motif domain containing 4A
chr16_+_69221028 0.57 ENST00000336278.4
 SNTB2
 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr19_+_35773242 0.57 ENST00000222304.3
 HAMP
 hepcidin antimicrobial peptide
chr9_-_13279563 0.56 ENST00000541718.1
 MPDZ
 multiple PDZ domain protein
chr17_-_47755338 0.56 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
 SPOP
 speckle-type POZ protein
chr1_-_153066998 0.55 ENST00000368750.3
 SPRR2E
 small proline-rich protein 2E
chr17_-_79869077 0.55 ENST00000570391.1
 PCYT2
 phosphate cytidylyltransferase 2, ethanolamine
chr19_+_39279838 0.55 ENST00000314980.4
 LGALS7B
 lectin, galactoside-binding, soluble, 7B
chr7_-_6523755 0.55 ENST00000436575.1
ENST00000258739.4
 DAGLB
KDELR2
 diacylglycerol lipase, beta
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr14_+_75746781 0.55 ENST00000555347.1
 FOS
 FBJ murine osteosarcoma viral oncogene homolog
chr16_+_85645007 0.55 ENST00000405402.2
 GSE1
 Gse1 coiled-coil protein
chr1_-_150780757 0.54 ENST00000271651.3
 CTSK
 cathepsin K
chr4_-_170924888 0.54 ENST00000502832.1
ENST00000393704.3
 MFAP3L
 microfibrillar-associated protein 3-like
chr14_+_55033815 0.53 ENST00000554335.1
 SAMD4A
 sterile alpha motif domain containing 4A
chr17_-_10452929 0.53 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
 MYH2
 myosin, heavy chain 2, skeletal muscle, adult
chr19_-_48894762 0.53 ENST00000600980.1
ENST00000330720.2
 KDELR1
 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr9_-_128003606 0.52 ENST00000324460.6
 HSPA5
 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr17_-_79869243 0.52 ENST00000538721.2
ENST00000573636.2
ENST00000571105.1
ENST00000576343.1
ENST00000572473.1
 PCYT2
 phosphate cytidylyltransferase 2, ethanolamine
chrX_+_99899180 0.52 ENST00000373004.3
 SRPX2
 sushi-repeat containing protein, X-linked 2
chr21_+_35014783 0.52 ENST00000381291.4
ENST00000381285.4
ENST00000399367.3
ENST00000399352.1
ENST00000399355.2
ENST00000399349.1
 ITSN1
 intersectin 1 (SH3 domain protein)
chr17_-_79869340 0.52 ENST00000538936.2
 PCYT2
 phosphate cytidylyltransferase 2, ethanolamine
chr15_+_90808919 0.51 ENST00000379095.3
 NGRN
 neugrin, neurite outgrowth associated
chr16_+_28834531 0.50 ENST00000570200.1
 ATXN2L
 ataxin 2-like
chr14_+_24701819 0.50 ENST00000560139.1
ENST00000559910.1
 GMPR2
 guanosine monophosphate reductase 2
chr13_+_115047097 0.49 ENST00000351487.5
 UPF3A
 UPF3 regulator of nonsense transcripts homolog A (yeast)
chr1_+_172502336 0.49 ENST00000263688.3
 SUCO
 SUN domain containing ossification factor
chr4_-_140222358 0.48 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
 NDUFC1
 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr17_-_40333099 0.48 ENST00000607371.1
 KCNH4
 potassium voltage-gated channel, subfamily H (eag-related), member 4
chr19_-_46526304 0.47 ENST00000008938.4
 PGLYRP1
 peptidoglycan recognition protein 1
chr1_+_17906970 0.47 ENST00000375415.1
 ARHGEF10L
 Rho guanine nucleotide exchange factor (GEF) 10-like
chrX_-_10645773 0.46 ENST00000453318.2
 MID1
 midline 1 (Opitz/BBB syndrome)
chr18_+_47088401 0.46 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
 LIPG
 lipase, endothelial
chr12_-_8815404 0.46 ENST00000359478.2
ENST00000396549.2
 MFAP5
 microfibrillar associated protein 5
chr17_+_39975544 0.45 ENST00000544340.1
 FKBP10
 FK506 binding protein 10, 65 kDa
chr8_-_49834299 0.45 ENST00000396822.1
 SNAI2
 snail family zinc finger 2
chr17_+_39975455 0.45 ENST00000455106.1
 FKBP10
 FK506 binding protein 10, 65 kDa
chr16_+_2587998 0.44 ENST00000441549.3
ENST00000268673.7
 PDPK1
 3-phosphoinositide dependent protein kinase-1
chr19_+_17337473 0.44 ENST00000598068.1
 OCEL1
 occludin/ELL domain containing 1
chr12_-_56121612 0.43 ENST00000546939.1
 CD63
 CD63 molecule
chrX_-_153775426 0.43 ENST00000393562.2
 G6PD
 glucose-6-phosphate dehydrogenase
chr14_+_24701628 0.43 ENST00000355299.4
ENST00000559836.1
 GMPR2
 guanosine monophosphate reductase 2
chr2_-_20251744 0.42 ENST00000175091.4
 LAPTM4A
 lysosomal protein transmembrane 4 alpha
chr14_-_24701539 0.41 ENST00000534348.1
ENST00000524927.1
ENST00000250495.5
 NEDD8-MDP1
NEDD8
 NEDD8-MDP1 readthrough
neural precursor cell expressed, developmentally down-regulated 8
chr22_+_35776828 0.41 ENST00000216117.8
 HMOX1
 heme oxygenase (decycling) 1
chr1_-_226129083 0.40 ENST00000420304.2
 LEFTY2
 left-right determination factor 2
chr6_-_30815936 0.40 ENST00000442852.1
 XXbac-BPG27H4.8
 XXbac-BPG27H4.8
chr7_-_71801980 0.40 ENST00000329008.5
 CALN1
 calneuron 1
chr9_-_140082983 0.39 ENST00000323927.2
 ANAPC2
 anaphase promoting complex subunit 2
chr3_+_52821841 0.39 ENST00000405128.3
 ITIH1
 inter-alpha-trypsin inhibitor heavy chain 1
chr6_+_43739697 0.38 ENST00000230480.6
 VEGFA
 vascular endothelial growth factor A
chr3_-_52443799 0.38 ENST00000470173.1
ENST00000296288.5
 BAP1
 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr4_+_90816033 0.38 ENST00000264790.2
ENST00000394981.1
 MMRN1
 multimerin 1
chr12_-_71551868 0.38 ENST00000247829.3
 TSPAN8
 tetraspanin 8
chr12_-_56121580 0.38 ENST00000550776.1
 CD63
 CD63 molecule
chr8_-_49833978 0.38 ENST00000020945.1
 SNAI2
 snail family zinc finger 2
chr11_-_66084508 0.37 ENST00000311330.3
 CD248
 CD248 molecule, endosialin
chr14_-_24664540 0.37 ENST00000530563.1
ENST00000528895.1
ENST00000528669.1
ENST00000532632.1
 TM9SF1
 transmembrane 9 superfamily member 1
chr1_+_155294342 0.37 ENST00000292254.4
 RUSC1
 RUN and SH3 domain containing 1
chr18_+_60382672 0.36 ENST00000400316.4
ENST00000262719.5
 PHLPP1
 PH domain and leucine rich repeat protein phosphatase 1
chr16_+_2587965 0.36 ENST00000342085.4
ENST00000566659.1
 PDPK1
 3-phosphoinositide dependent protein kinase-1
chr19_+_45973120 0.36 ENST00000592811.1
ENST00000586615.1
 FOSB
 FBJ murine osteosarcoma viral oncogene homolog B
chr14_-_103523745 0.35 ENST00000361246.2
 CDC42BPB
 CDC42 binding protein kinase beta (DMPK-like)
chrX_-_134049262 0.35 ENST00000370783.3
 MOSPD1
 motile sperm domain containing 1
chr9_+_17134980 0.35 ENST00000380647.3
 CNTLN
 centlein, centrosomal protein
chr17_-_79869228 0.35 ENST00000570388.1
 PCYT2
 phosphate cytidylyltransferase 2, ethanolamine
chr1_+_155294264 0.35 ENST00000368349.4
 RUSC1
 RUN and SH3 domain containing 1
chr1_-_94079648 0.35 ENST00000370247.3
 BCAR3
 breast cancer anti-estrogen resistance 3
chr7_-_72972319 0.35 ENST00000223368.2
 BCL7B
 B-cell CLL/lymphoma 7B
chr17_+_25799008 0.34 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
 KSR1
 kinase suppressor of ras 1
chrX_+_47077632 0.34 ENST00000457458.2
 CDK16
 cyclin-dependent kinase 16
chr20_+_1115821 0.34 ENST00000435720.1
 PSMF1
 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr20_-_4982132 0.33 ENST00000338244.1
ENST00000424750.2
 SLC23A2
 solute carrier family 23 (ascorbic acid transporter), member 2
chr12_-_71551652 0.33 ENST00000546561.1
 TSPAN8
 tetraspanin 8
chr1_+_39456895 0.33 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
 AKIRIN1
 akirin 1
chr5_+_54320078 0.33 ENST00000231009.2
 GZMK
 granzyme K (granzyme 3; tryptase II)
chr1_-_52456352 0.32 ENST00000371655.3
 RAB3B
 RAB3B, member RAS oncogene family
chr6_+_7107999 0.32 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
 RREB1
 ras responsive element binding protein 1
chr8_-_25281747 0.32 ENST00000421054.2
 GNRH1
 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr6_+_167536230 0.32 ENST00000341935.5
ENST00000349984.4
 CCR6
 chemokine (C-C motif) receptor 6
chr1_-_149889382 0.31 ENST00000369145.1
ENST00000369146.3
 SV2A
 synaptic vesicle glycoprotein 2A
chr9_+_17135016 0.31 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
 CNTLN
 centlein, centrosomal protein
chr9_-_14314566 0.31 ENST00000397579.2
 NFIB
 nuclear factor I/B
chr1_-_226129189 0.31 ENST00000366820.5
 LEFTY2
 left-right determination factor 2
chr9_-_14314518 0.31 ENST00000397581.2
 NFIB
 nuclear factor I/B
chr20_+_44509857 0.30 ENST00000372523.1
ENST00000372520.1
 ZSWIM1
 zinc finger, SWIM-type containing 1
chr19_+_54926601 0.30 ENST00000301194.4
 TTYH1
 tweety family member 1
chr17_+_76311791 0.30 ENST00000586321.1
 AC061992.2
 AC061992.2
chr1_+_27114418 0.30 ENST00000078527.4
 PIGV
 phosphatidylinositol glycan anchor biosynthesis, class V

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 4.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 4.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 3.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 2.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 2.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 6.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 2.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 3.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.6 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.3 3.8 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
1.2 3.7 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.9 3.5 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.8 3.3 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.7 2.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.7 5.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.7 3.4 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.6 1.9 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.6 1.8 GO:0060621 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.6 3.6 GO:0030421 defecation(GO:0030421)
0.6 1.7 GO:0061010 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.5 2.1 GO:0014028 notochord formation(GO:0014028)
0.5 2.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.4 2.1 GO:1902896 terminal web assembly(GO:1902896)
0.4 1.5 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.4 1.4 GO:1904327 maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.3 1.4 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.3 2.0 GO:0061517 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.3 1.0 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.3 0.9 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.3 0.9 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.3 3.0 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.3 0.8 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.3 1.0 GO:1903288 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
0.2 0.7 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2 2.0 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 1.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 4.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 0.9 GO:0099542 retrograde trans-synaptic signaling(GO:0098917) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.2 0.5 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.2 1.1 GO:0032571 response to vitamin K(GO:0032571)
0.2 0.6 GO:2000777 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.2 2.3 GO:0035437 maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.2 0.6 GO:1904479 cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.2 2.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 1.5 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.2 0.3 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.2 0.5 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
0.2 1.5 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.7 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 1.9 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 0.4 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 3.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.4 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
0.1 0.7 GO:0003070 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.4 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.8 GO:0035803 egg coat formation(GO:0035803)
0.1 0.4 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.4 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 2.7 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 0.7 GO:0046208 spermine catabolic process(GO:0046208)
0.1 0.6 GO:0048478 replication fork protection(GO:0048478)
0.1 0.5 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 2.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.8 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.1 0.3 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.1 0.5 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.3 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 0.2 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 0.6 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.2 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 1.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.3 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 1.8 GO:0006907 pinocytosis(GO:0006907)
0.1 1.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.6 GO:0051414 response to cortisol(GO:0051414)
0.1 0.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.3 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 1.3 GO:0016264 gap junction assembly(GO:0016264)
0.1 2.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.2 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.8 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 3.7 GO:0021545 cranial nerve development(GO:0021545)
0.1 0.8 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 0.3 GO:0051582 peptidyl-cysteine methylation(GO:0018125) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.1 0.6 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.4 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.2 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.1 2.0 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.9 GO:0002021 response to dietary excess(GO:0002021)
0.0 1.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.3 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.7 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0 0.5 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.7 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050) positive regulation of female receptivity(GO:0045925)
0.0 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.4 GO:0002911 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.3 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 1.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 1.0 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.3 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 2.1 GO:0007566 embryo implantation(GO:0007566)
0.0 2.6 GO:0007602 phototransduction(GO:0007602)
0.0 0.5 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 1.3 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 1.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.9 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.6 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0060969 negative regulation of gene silencing(GO:0060969)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0060579 ventral spinal cord interneuron specification(GO:0021521) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) cell fate specification involved in pattern specification(GO:0060573) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0 0.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.4 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0039003 pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) thyroid-stimulating hormone secretion(GO:0070460) kidney rudiment formation(GO:0072003) kidney field specification(GO:0072004) metanephric nephron tubule formation(GO:0072289) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.8 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.5 GO:0032967 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0 0.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.0 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.0 0.3 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 1.0 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.0 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.4 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.0 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0043383 negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.0 0.0 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.2 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.8 3.4 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.8 3.3 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.8 3.9 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.6 5.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.5 1.5 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.5 2.5 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.4 1.8 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.4 1.8 GO:0005046 KDEL sequence binding(GO:0005046)
0.4 1.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.4 2.3 GO:0003796 lysozyme activity(GO:0003796)
0.3 0.6 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.2 0.7 GO:0052895 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.2 0.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 3.0 GO:0038132 neuregulin binding(GO:0038132)
0.2 3.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 4.1 GO:0051787 misfolded protein binding(GO:0051787)
0.2 3.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 1.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 1.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.2 0.5 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 0.9 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.7 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 1.3 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 1.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.3 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 5.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.8 GO:0032190 acrosin binding(GO:0032190)
0.1 0.3 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 0.8 GO:0046790 virion binding(GO:0046790)
0.1 0.4 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.7 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 0.3 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 1.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.6 GO:0036310 annealing helicase activity(GO:0036310)
0.1 1.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 1.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.7 GO:0045159 myosin II binding(GO:0045159)
0.1 1.7 GO:0030371 translation repressor activity(GO:0030371)
0.1 5.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 1.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.2 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.1 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.7 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.3 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 4.9 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 2.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 2.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.4 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.9 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.1 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.9 GO:0031625 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 1.6 GO:0020037 heme binding(GO:0020037)
0.0 0.0 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.1 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.4 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 PID ARF 3PATHWAY Arf1 pathway
0.1 2.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 2.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 5.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 4.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 3.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 2.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 2.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 2.0 PID BMP PATHWAY BMP receptor signaling
0.0 4.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.9 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.9 PID FOXO PATHWAY FoxO family signaling
0.0 1.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 2.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 4.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.4 5.9 GO:0005916 fascia adherens(GO:0005916)
0.4 1.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.3 3.8 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.2 2.6 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.2 0.5 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 1.0 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.2 5.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 1.0 GO:1990357 terminal web(GO:1990357)
0.2 0.9 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.9 GO:0043196 varicosity(GO:0043196)
0.1 0.8 GO:0071203 WASH complex(GO:0071203)
0.1 1.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 2.0 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.7 GO:0032433 filopodium tip(GO:0032433)
0.1 1.1 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 1.3 GO:0005922 connexon complex(GO:0005922)
0.1 0.5 GO:0036021 endolysosome lumen(GO:0036021)
0.1 1.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.6 GO:0045179 apical cortex(GO:0045179)
0.1 2.6 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.1 7.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.3 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 0.5 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.6 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.1 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 1.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.2 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.6 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.7 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 7.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 2.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.6 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 1.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 3.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 2.4 GO:0030018 Z disc(GO:0030018)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)