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ENCODE cell lines, expression (Ernst 2011)

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Results for TBX19

Z-value: 0.73

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Transcription factors associated with TBX19

Gene Symbol Gene ID Gene Info
TBX19
ENSG00000143178.8 TBX19

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX19hg19_v2_chr1_+_168250194_1682502780.049.0e-01Click!

Activity profile of TBX19 motif

Sorted Z-values of TBX19 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX19

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_113594279 1.83 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
 IL1B
 interleukin 1, beta
chr18_+_61554932 1.62 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
 SERPINB2
 serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr1_+_46640750 1.55 ENST00000372003.1
 TSPAN1
 tetraspanin 1
chr19_+_38755042 1.31 ENST00000301244.7
 SPINT2
 serine peptidase inhibitor, Kunitz type, 2
chr6_-_2842087 1.14 ENST00000537185.1
 SERPINB1
 serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr11_-_115375107 1.13 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
 CADM1
 cell adhesion molecule 1
chr5_+_96211643 1.12 ENST00000437043.3
ENST00000510373.1
 ERAP2
 endoplasmic reticulum aminopeptidase 2
chr6_-_2842219 1.11 ENST00000380739.5
 SERPINB1
 serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr5_+_96212185 1.08 ENST00000379904.4
 ERAP2
 endoplasmic reticulum aminopeptidase 2
chr10_-_95241951 0.92 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
 MYOF
 myoferlin
chr10_-_95242044 0.88 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
 MYOF
 myoferlin
chr7_-_76255444 0.87 ENST00000454397.1
 POMZP3
 POM121 and ZP3 fusion
chr3_+_118905564 0.86 ENST00000460625.1
 UPK1B
 uroplakin 1B
chr11_-_119993734 0.79 ENST00000533302.1
 TRIM29
 tripartite motif containing 29
chr5_+_125695805 0.74 ENST00000513040.1
 GRAMD3
 GRAM domain containing 3
chr21_+_39628655 0.73 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
chr4_-_156298028 0.67 ENST00000433024.1
ENST00000379248.2
 MAP9
 microtubule-associated protein 9
chr20_+_44036620 0.66 ENST00000372710.3
 DBNDD2
 dysbindin (dystrobrevin binding protein 1) domain containing 2
chr2_+_62900986 0.64 ENST00000405015.3
ENST00000413434.1
ENST00000426940.1
ENST00000449820.1
 EHBP1
 EH domain binding protein 1
chr10_+_90750378 0.57 ENST00000355740.2
ENST00000352159.4
 FAS
 Fas cell surface death receptor
chr4_-_57976544 0.54 ENST00000295666.4
ENST00000537922.1
 IGFBP7
 insulin-like growth factor binding protein 7
chr1_+_19923454 0.53 ENST00000602662.1
ENST00000602293.1
ENST00000322753.6
 MINOS1-NBL1
MINOS1
 MINOS1-NBL1 readthrough
mitochondrial inner membrane organizing system 1
chr22_+_31477296 0.50 ENST00000426927.1
ENST00000440425.1
ENST00000358743.1
ENST00000347557.2
ENST00000333137.7
 SMTN
 smoothelin
chr6_+_123110465 0.44 ENST00000539041.1
 SMPDL3A
 sphingomyelin phosphodiesterase, acid-like 3A
chr14_+_32546274 0.44 ENST00000396582.2
 ARHGAP5
 Rho GTPase activating protein 5
chr10_+_90750493 0.43 ENST00000357339.2
ENST00000355279.2
 FAS
 Fas cell surface death receptor
chr2_-_9563575 0.35 ENST00000488451.1
ENST00000238091.4
ENST00000355346.4
 ITGB1BP1
 integrin beta 1 binding protein 1
chr14_+_69658194 0.34 ENST00000409018.3
ENST00000409014.1
ENST00000409675.1
 EXD2
 exonuclease 3'-5' domain containing 2
chr16_-_66583701 0.32 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
 TK2
 thymidine kinase 2, mitochondrial
chr12_-_10962767 0.31 ENST00000240691.2
 TAS2R9
 taste receptor, type 2, member 9
chr2_-_9563319 0.30 ENST00000497105.1
ENST00000360635.3
ENST00000359712.3
 ITGB1BP1
 integrin beta 1 binding protein 1
chr2_-_85636928 0.30 ENST00000449030.1
 CAPG
 capping protein (actin filament), gelsolin-like
chr15_-_60771128 0.26 ENST00000558512.1
ENST00000561114.1
 NARG2
 NMDA receptor regulated 2
chr7_-_43946175 0.23 ENST00000603700.1
ENST00000402306.3
ENST00000443736.1
ENST00000446958.1
 URGCP-MRPS24
URGCP
 URGCP-MRPS24 readthrough
upregulator of cell proliferation
chrX_-_15402498 0.22 ENST00000297904.3
 FIGF
 c-fos induced growth factor (vascular endothelial growth factor D)
chr8_-_19540266 0.22 ENST00000311540.4
 CSGALNACT1
 chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr1_-_167522982 0.22 ENST00000370509.4
 CREG1
 cellular repressor of E1A-stimulated genes 1
chr2_-_9563469 0.22 ENST00000484735.1
ENST00000456913.2
 ITGB1BP1
 integrin beta 1 binding protein 1
chr8_-_19540086 0.22 ENST00000332246.6
 CSGALNACT1
 chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr20_-_3762087 0.21 ENST00000379756.3
 SPEF1
 sperm flagellar 1
chr6_-_27880174 0.20 ENST00000303324.2
 OR2B2
 olfactory receptor, family 2, subfamily B, member 2
chr5_+_140165876 0.20 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
 PCDHA1
 protocadherin alpha 1
chr1_-_146040968 0.19 ENST00000401010.3
 NBPF11
 neuroblastoma breakpoint family, member 11
chr2_+_201754135 0.19 ENST00000409357.1
ENST00000409129.2
 NIF3L1
 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr9_+_125137565 0.19 ENST00000373698.5
 PTGS1
 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_+_152214098 0.19 ENST00000243347.3
 TNFAIP6
 tumor necrosis factor, alpha-induced protein 6
chr14_+_24458123 0.18 ENST00000545240.1
ENST00000382755.4
 DHRS4L2
 dehydrogenase/reductase (SDR family) member 4 like 2
chr2_+_201754050 0.17 ENST00000426253.1
ENST00000416651.1
ENST00000454952.1
ENST00000409020.1
ENST00000359683.4
 NIF3L1
 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr20_-_7921090 0.17 ENST00000378789.3
 HAO1
 hydroxyacid oxidase (glycolate oxidase) 1
chr11_+_46740730 0.17 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
 F2
 coagulation factor II (thrombin)
chrX_+_150866779 0.17 ENST00000370353.3
 PRRG3
 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr15_-_65809581 0.16 ENST00000341861.5
 DPP8
 dipeptidyl-peptidase 8
chr20_-_22565101 0.15 ENST00000419308.2
 FOXA2
 forkhead box A2
chr2_+_228337079 0.14 ENST00000409315.1
ENST00000373671.3
ENST00000409171.1
 AGFG1
 ArfGAP with FG repeats 1
chr14_+_24458021 0.13 ENST00000397071.1
ENST00000559411.1
ENST00000335125.6
 DHRS4L2
 dehydrogenase/reductase (SDR family) member 4 like 2
chr4_+_69962185 0.13 ENST00000305231.7
 UGT2B7
 UDP glucuronosyltransferase 2 family, polypeptide B7
chr2_-_211341411 0.13 ENST00000233714.4
ENST00000443314.1
ENST00000441020.3
ENST00000450366.2
ENST00000431941.2
 LANCL1
 LanC lantibiotic synthetase component C-like 1 (bacterial)
chr19_-_46526304 0.13 ENST00000008938.4
 PGLYRP1
 peptidoglycan recognition protein 1
chr14_+_24458093 0.11 ENST00000558753.1
ENST00000537912.1
 DHRS4L2
 dehydrogenase/reductase (SDR family) member 4 like 2
chr19_+_852291 0.11 ENST00000263621.1
 ELANE
 elastase, neutrophil expressed
chr12_-_10875831 0.10 ENST00000279550.7
ENST00000228251.4
 YBX3
 Y box binding protein 3
chr3_+_132316081 0.10 ENST00000249887.2
 ACKR4
 atypical chemokine receptor 4
chr17_+_4736627 0.10 ENST00000355280.6
ENST00000347992.7
 MINK1
 misshapen-like kinase 1
chr1_+_153963227 0.10 ENST00000368567.4
ENST00000392558.4
 RPS27
 ribosomal protein S27
chr10_+_103113802 0.10 ENST00000370187.3
 BTRC
 beta-transducin repeat containing E3 ubiquitin protein ligase
chr8_-_134115118 0.09 ENST00000395352.3
ENST00000338087.5
 SLA
 Src-like-adaptor
chr9_+_78505581 0.09 ENST00000376767.3
ENST00000376752.4
 PCSK5
 proprotein convertase subtilisin/kexin type 5
chr1_-_23521222 0.09 ENST00000374619.1
 HTR1D
 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr3_+_32726774 0.09 ENST00000538368.1
 CNOT10
 CCR4-NOT transcription complex, subunit 10
chr19_+_4247070 0.09 ENST00000262962.7
 CCDC94
 coiled-coil domain containing 94
chr9_+_78505554 0.09 ENST00000545128.1
 PCSK5
 proprotein convertase subtilisin/kexin type 5
chr18_-_3874752 0.08 ENST00000534970.1
 DLGAP1
 discs, large (Drosophila) homolog-associated protein 1
chr1_-_23520755 0.08 ENST00000314113.3
 HTR1D
 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr12_+_110011571 0.08 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
 MVK
 mevalonate kinase
chr20_-_50385138 0.08 ENST00000338821.5
 ATP9A
 ATPase, class II, type 9A
chr5_-_39270725 0.08 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
 FYB
 FYN binding protein
chr17_+_41561317 0.08 ENST00000540306.1
ENST00000262415.3
ENST00000605777.1
 DHX8
 DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr1_+_16090914 0.07 ENST00000441801.2
 FBLIM1
 filamin binding LIM protein 1
chr2_-_162931052 0.07 ENST00000360534.3
 DPP4
 dipeptidyl-peptidase 4
chr10_+_43916052 0.07 ENST00000442526.2
 RP11-517P14.2
 RP11-517P14.2
chr17_-_32690239 0.07 ENST00000225842.3
 CCL1
 chemokine (C-C motif) ligand 1
chr3_-_49466686 0.06 ENST00000273598.3
ENST00000436744.2
 NICN1
 nicolin 1
chr5_-_78281603 0.06 ENST00000264914.4
 ARSB
 arylsulfatase B
chr1_+_117297007 0.06 ENST00000369478.3
ENST00000369477.1
 CD2
 CD2 molecule
chr17_+_3118915 0.06 ENST00000304094.1
 OR1A1
 olfactory receptor, family 1, subfamily A, member 1
chr19_-_39421377 0.06 ENST00000430193.3
ENST00000600042.1
ENST00000221431.6
 SARS2
 seryl-tRNA synthetase 2, mitochondrial
chr4_+_26321284 0.06 ENST00000506956.1
ENST00000512671.1
ENST00000345843.3
ENST00000342295.1
 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
chr6_+_42847649 0.06 ENST00000424341.2
ENST00000602561.1
 RPL7L1
 ribosomal protein L7-like 1
chr6_+_153552455 0.06 ENST00000392385.2
 AL590867.1
 Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr7_+_117251671 0.06 ENST00000468795.1
 CFTR
 cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr10_+_106034884 0.05 ENST00000369707.2
ENST00000429569.2
 GSTO2
 glutathione S-transferase omega 2
chr16_+_66995121 0.05 ENST00000303334.4
 CES3
 carboxylesterase 3
chr12_-_9360966 0.05 ENST00000261336.2
 PZP
 pregnancy-zone protein
chr16_+_66995144 0.05 ENST00000394037.1
 CES3
 carboxylesterase 3
chr6_+_22569784 0.05 ENST00000510882.2
 HDGFL1
 hepatoma derived growth factor-like 1
chrX_+_107288239 0.05 ENST00000217957.5
 VSIG1
 V-set and immunoglobulin domain containing 1
chr19_-_58514129 0.04 ENST00000552184.1
ENST00000546715.1
ENST00000536132.1
ENST00000547828.1
ENST00000547121.1
ENST00000551380.1
 ZNF606
 zinc finger protein 606
chr12_+_120740119 0.04 ENST00000536460.1
ENST00000202967.4
 SIRT4
 sirtuin 4
chr10_+_12171636 0.04 ENST00000379051.1
ENST00000379033.3
ENST00000441368.1
ENST00000298428.9
ENST00000304267.8
 SEC61A2
 Sec61 alpha 2 subunit (S. cerevisiae)
chr15_-_20170354 0.03 ENST00000338912.5
 IGHV1OR15-9
 immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr9_-_100684845 0.03 ENST00000375119.3
 C9orf156
 chromosome 9 open reading frame 156
chr3_+_119499331 0.03 ENST00000393716.2
ENST00000466380.1
 NR1I2
 nuclear receptor subfamily 1, group I, member 2
chr11_-_59383617 0.03 ENST00000263847.1
 OSBP
 oxysterol binding protein
chr3_-_150264272 0.03 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
 SERP1
 stress-associated endoplasmic reticulum protein 1
chr3_+_46204959 0.03 ENST00000357422.2
 CCR3
 chemokine (C-C motif) receptor 3
chr13_+_21141208 0.03 ENST00000351808.5
 IFT88
 intraflagellar transport 88 homolog (Chlamydomonas)
chrX_+_107288197 0.02 ENST00000415430.3
 VSIG1
 V-set and immunoglobulin domain containing 1
chr10_-_97200772 0.02 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
 SORBS1
 sorbin and SH3 domain containing 1
chr20_+_43835638 0.02 ENST00000372781.3
ENST00000244069.6
 SEMG1
 semenogelin I
chr17_+_55162453 0.02 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
 AKAP1
 A kinase (PRKA) anchor protein 1
chr5_+_54320078 0.01 ENST00000231009.2
 GZMK
 granzyme K (granzyme 3; tryptase II)
chr12_-_11036844 0.01 ENST00000428168.2
 PRH1
 proline-rich protein HaeIII subfamily 1
chr12_+_8276433 0.01 ENST00000345999.3
ENST00000352620.3
ENST00000360500.3
 CLEC4A
 C-type lectin domain family 4, member A
chr16_-_20339123 0.01 ENST00000381360.5
 GP2
 glycoprotein 2 (zymogen granule membrane)
chr14_-_58894332 0.01 ENST00000395159.2
 TIMM9
 translocase of inner mitochondrial membrane 9 homolog (yeast)
chr7_+_93535817 0.01 ENST00000248572.5
 GNGT1
 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr19_+_58111241 0.01 ENST00000597700.1
ENST00000332854.6
ENST00000597864.1
 ZNF530
 zinc finger protein 530
chr12_-_49319265 0.01 ENST00000552878.1
ENST00000453172.2
 FKBP11
 FK506 binding protein 11, 19 kDa
chr8_-_6795823 0.01 ENST00000297435.2
 DEFA4
 defensin, alpha 4, corticostatin
chr21_-_35884573 0.00 ENST00000399286.2
 KCNE1
 potassium voltage-gated channel, Isk-related family, member 1
chr11_+_27062502 0.00 ENST00000263182.3
 BBOX1
 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.3 1.3 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3 1.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 2.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 1.0 GO:0097527 Fas signaling pathway(GO:0036337) necroptotic signaling pathway(GO:0097527)
0.1 1.8 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.9 GO:0035803 egg coat formation(GO:0035803)
0.1 0.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276) chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.9 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 0.3 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.5 GO:0051414 response to cortisol(GO:0051414)
0.1 0.7 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 1.8 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
0.0 0.2 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.0 0.1 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.2 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.2 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.1 GO:1905068 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.7 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.3 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.0 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 1.0 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 1.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.8 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 4.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.4 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.3 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 1.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.9 GO:0032190 acrosin binding(GO:0032190)
0.1 2.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.2 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 5.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.1 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 1.1 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)