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ENCODE cell lines, expression (Ernst 2011)

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Results for TBX20

Z-value: 0.75

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Transcription factors associated with TBX20

Gene Symbol Gene ID Gene Info
TBX20
ENSG00000164532.10 TBX20

Activity profile of TBX20 motif

Sorted Z-values of TBX20 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX20

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr16_+_57662419 2.91 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
 GPR56
 G protein-coupled receptor 56
chr17_-_7080227 0.99 ENST00000574330.1
 ASGR1
 asialoglycoprotein receptor 1
chr10_+_114135004 0.89 ENST00000393081.1
 ACSL5
 acyl-CoA synthetase long-chain family member 5
chr10_+_114135952 0.77 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
 ACSL5
 acyl-CoA synthetase long-chain family member 5
chr3_+_142315225 0.74 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
 PLS1
 plastin 1
chrX_+_78200913 0.74 ENST00000171757.2
 P2RY10
 purinergic receptor P2Y, G-protein coupled, 10
chrX_+_78200829 0.73 ENST00000544091.1
 P2RY10
 purinergic receptor P2Y, G-protein coupled, 10
chr2_+_61108650 0.69 ENST00000295025.8
 REL
 v-rel avian reticuloendotheliosis viral oncogene homolog
chr19_+_56915668 0.53 ENST00000333201.9
ENST00000391778.3
 ZNF583
 zinc finger protein 583
chr19_-_4540486 0.51 ENST00000306390.6
 LRG1
 leucine-rich alpha-2-glycoprotein 1
chr2_+_61108771 0.49 ENST00000394479.3
 REL
 v-rel avian reticuloendotheliosis viral oncogene homolog
chr1_+_162760513 0.46 ENST00000367915.1
ENST00000367917.3
ENST00000254521.3
ENST00000367913.1
 HSD17B7
 hydroxysteroid (17-beta) dehydrogenase 7
chr17_-_3599327 0.46 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
 P2RX5
 purinergic receptor P2X, ligand-gated ion channel, 5
chr3_+_40428647 0.40 ENST00000301825.3
ENST00000439533.1
ENST00000456402.1
 ENTPD3
 ectonucleoside triphosphate diphosphohydrolase 3
chr17_-_3599696 0.38 ENST00000225328.5
 P2RX5
 purinergic receptor P2X, ligand-gated ion channel, 5
chr17_-_3599492 0.37 ENST00000435558.1
ENST00000345901.3
 P2RX5
 purinergic receptor P2X, ligand-gated ion channel, 5
chr15_-_22448819 0.37 ENST00000604066.1
 IGHV1OR15-1
 immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr8_+_27183033 0.36 ENST00000420218.2
 PTK2B
 protein tyrosine kinase 2 beta
chr8_+_27182862 0.35 ENST00000521164.1
ENST00000346049.5
 PTK2B
 protein tyrosine kinase 2 beta
chr13_+_113760098 0.35 ENST00000346342.3
ENST00000541084.1
ENST00000375581.3
 F7
 coagulation factor VII (serum prothrombin conversion accelerator)
chr1_+_43824669 0.34 ENST00000372462.1
 CDC20
 cell division cycle 20
chr6_-_136788001 0.32 ENST00000544465.1
 MAP7
 microtubule-associated protein 7
chr5_+_133861339 0.29 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
 PHF15
 jade family PHD finger 2
chr2_+_173940442 0.26 ENST00000409176.2
ENST00000338983.3
ENST00000431503.2
 MLTK
 Mitogen-activated protein kinase kinase kinase MLT
chr6_-_84937314 0.26 ENST00000257766.4
ENST00000403245.3
 KIAA1009
 KIAA1009
chr12_+_15475331 0.25 ENST00000281171.4
 PTPRO
 protein tyrosine phosphatase, receptor type, O
chr2_+_207630081 0.25 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
 FASTKD2
 FAST kinase domains 2
chr12_+_15475462 0.25 ENST00000543886.1
ENST00000348962.2
 PTPRO
 protein tyrosine phosphatase, receptor type, O
chr9_-_72287191 0.21 ENST00000265381.4
 APBA1
 amyloid beta (A4) precursor protein-binding, family A, member 1
chr15_-_74504560 0.20 ENST00000449139.2
 STRA6
 stimulated by retinoic acid 6
chr15_-_74504597 0.20 ENST00000416286.3
 STRA6
 stimulated by retinoic acid 6
chr2_+_64068074 0.19 ENST00000394417.2
ENST00000484142.1
ENST00000482668.1
ENST00000467648.2
 UGP2
 UDP-glucose pyrophosphorylase 2
chr5_+_161494521 0.18 ENST00000356592.3
 GABRG2
 gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr22_-_46283597 0.17 ENST00000451118.1
 WI2-85898F10.1
 WI2-85898F10.1
chr14_-_106453155 0.16 ENST00000390594.2
 IGHV1-2
 immunoglobulin heavy variable 1-2
chr2_-_219134822 0.15 ENST00000444053.1
ENST00000248450.4
 AAMP
 angio-associated, migratory cell protein
chr20_-_48782639 0.15 ENST00000435301.2
 RP11-112L6.3
 RP11-112L6.3
chr20_+_44509857 0.14 ENST00000372523.1
ENST00000372520.1
 ZSWIM1
 zinc finger, SWIM-type containing 1
chr15_-_38519066 0.13 ENST00000561320.1
ENST00000561161.1
 RP11-346D14.1
 RP11-346D14.1
chr6_-_2842219 0.12 ENST00000380739.5
 SERPINB1
 serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr2_-_219134343 0.12 ENST00000447885.1
ENST00000420660.1
 AAMP
 angio-associated, migratory cell protein
chr4_-_26492076 0.10 ENST00000295589.3
 CCKAR
 cholecystokinin A receptor
chr3_-_15140629 0.10 ENST00000507357.1
ENST00000449050.1
ENST00000253699.3
ENST00000435849.3
ENST00000476527.2
 ZFYVE20
 zinc finger, FYVE domain containing 20
chr1_+_147013182 0.10 ENST00000234739.3
 BCL9
 B-cell CLL/lymphoma 9
chr6_-_2842087 0.10 ENST00000537185.1
 SERPINB1
 serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr12_-_121477039 0.08 ENST00000257570.5
 OASL
 2'-5'-oligoadenylate synthetase-like
chr11_+_6281036 0.08 ENST00000532715.1
ENST00000525014.1
ENST00000531712.1
ENST00000525462.1
 CCKBR
 cholecystokinin B receptor
chr1_-_11865982 0.07 ENST00000418034.1
 MTHFR
 methylenetetrahydrofolate reductase (NAD(P)H)
chr2_+_176972000 0.07 ENST00000249504.5
 HOXD11
 homeobox D11
chr7_-_139763521 0.06 ENST00000263549.3
 PARP12
 poly (ADP-ribose) polymerase family, member 12
chr3_-_183273477 0.04 ENST00000341319.3
 KLHL6
 kelch-like family member 6
chr1_-_154909329 0.03 ENST00000368467.3
 PMVK
 phosphomevalonate kinase
chr1_-_158300747 0.03 ENST00000451207.1
 CD1B
 CD1b molecule
chr7_-_142207004 0.03 ENST00000426318.2
 TRBV10-2
 T cell receptor beta variable 10-2
chr11_-_89540388 0.02 ENST00000532501.2
 TRIM49
 tripartite motif containing 49
chr1_+_11866207 0.02 ENST00000312413.6
ENST00000346436.6
 CLCN6
 chloride channel, voltage-sensitive 6

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:1990357 terminal web(GO:1990357)
0.1 1.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.2 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.2 0.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.7 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.3 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 2.7 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 0.4 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 1.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 1.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.2 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.1 0.4 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.1 0.3 GO:1902775 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 1.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.5 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 0.5 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 1.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 1.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.2 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.2 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.1 0.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.4 GO:0051183 vitamin transporter activity(GO:0051183)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.