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ENCODE cell lines, expression (Ernst 2011)

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Results for TBX21_TBR1

Z-value: 0.68

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Transcription factors associated with TBX21_TBR1

Gene Symbol Gene ID Gene Info
TBX21
ENSG00000073861.2 TBX21
TBR1
ENSG00000136535.10 TBR1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX21hg19_v2_chr17_+_45810594_458106100.332.2e-01Click!
TBR1hg19_v2_chr2_+_162272605_162272753-0.019.7e-01Click!

Activity profile of TBX21_TBR1 motif

Sorted Z-values of TBX21_TBR1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX21_TBR1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_152146385 1.71 ENST00000414946.1
ENST00000243346.5
 NMI
 N-myc (and STAT) interactor
chr21_-_15918618 1.52 ENST00000400564.1
ENST00000400566.1
 SAMSN1
 SAM domain, SH3 domain and nuclear localization signals 1
chr4_-_73434498 1.45 ENST00000286657.4
 ADAMTS3
 ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr11_-_33913708 1.28 ENST00000257818.2
 LMO2
 LIM domain only 2 (rhombotin-like 1)
chr15_-_83316254 1.22 ENST00000567678.1
ENST00000450751.2
 CPEB1
 cytoplasmic polyadenylation element binding protein 1
chr10_+_94451574 1.17 ENST00000492654.2
 HHEX
 hematopoietically expressed homeobox
chr7_-_87849340 1.13 ENST00000419179.1
ENST00000265729.2
 SRI
 sorcin
chr15_-_83316087 0.99 ENST00000568757.1
 CPEB1
 cytoplasmic polyadenylation element binding protein 1
chr11_-_85779971 0.90 ENST00000393346.3
 PICALM
 phosphatidylinositol binding clathrin assembly protein
chr1_-_156786530 0.89 ENST00000368198.3
 SH2D2A
 SH2 domain containing 2A
chr2_-_200322723 0.88 ENST00000417098.1
 SATB2
 SATB homeobox 2
chr22_-_41215291 0.86 ENST00000542412.1
ENST00000544408.1
 SLC25A17
 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr7_+_107220660 0.85 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
 BCAP29
 B-cell receptor-associated protein 29
chr22_-_41215328 0.84 ENST00000434185.1
ENST00000435456.2
 SLC25A17
 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr16_+_12058961 0.82 ENST00000053243.1
 TNFRSF17
 tumor necrosis factor receptor superfamily, member 17
chr10_-_23003460 0.81 ENST00000376573.4
 PIP4K2A
 phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr1_-_156786634 0.81 ENST00000392306.2
ENST00000368199.3
 SH2D2A
 SH2 domain containing 2A
chr19_-_13213662 0.80 ENST00000264824.4
 LYL1
 lymphoblastic leukemia derived sequence 1
chr11_+_59824060 0.79 ENST00000395032.2
ENST00000358152.2
 MS4A3
 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr11_+_59824127 0.79 ENST00000278865.3
 MS4A3
 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr15_+_40861487 0.76 ENST00000315616.7
ENST00000559271.1
 RPUSD2
 RNA pseudouridylate synthase domain containing 2
chr16_+_12059050 0.74 ENST00000396495.3
 TNFRSF17
 tumor necrosis factor receptor superfamily, member 17
chr13_+_42031679 0.73 ENST00000379359.3
 RGCC
 regulator of cell cycle
chr17_-_38721711 0.70 ENST00000578085.1
ENST00000246657.2
 CCR7
 chemokine (C-C motif) receptor 7
chr17_+_34538310 0.70 ENST00000444414.1
ENST00000378350.4
ENST00000389068.5
ENST00000588929.1
ENST00000589079.1
ENST00000589336.1
ENST00000400702.4
ENST00000591167.1
ENST00000586598.1
ENST00000591637.1
ENST00000378352.4
ENST00000358756.5
 CCL4L1
 chemokine (C-C motif) ligand 4-like 1
chr7_+_143013198 0.70 ENST00000343257.2
 CLCN1
 chloride channel, voltage-sensitive 1
chr11_+_114271251 0.68 ENST00000375490.5
 RBM7
 RNA binding motif protein 7
chr1_-_163172625 0.67 ENST00000527988.1
ENST00000531476.1
ENST00000530507.1
 RGS5
 regulator of G-protein signaling 5
chr1_+_182758900 0.64 ENST00000367555.1
ENST00000367554.3
 NPL
 N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr1_-_25256368 0.63 ENST00000308873.6
 RUNX3
 runt-related transcription factor 3
chr17_+_34431212 0.63 ENST00000394495.1
 CCL4
 chemokine (C-C motif) ligand 4
chr1_+_174843548 0.62 ENST00000478442.1
ENST00000465412.1
 RABGAP1L
 RAB GTPase activating protein 1-like
chr4_+_140222609 0.62 ENST00000296543.5
ENST00000398947.1
 NAA15
 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr3_-_107777208 0.60 ENST00000398258.3
 CD47
 CD47 molecule
chr7_-_150652924 0.60 ENST00000330883.4
 KCNH2
 potassium voltage-gated channel, subfamily H (eag-related), member 2
chr16_+_12059091 0.58 ENST00000562385.1
 TNFRSF17
 tumor necrosis factor receptor superfamily, member 17
chr16_-_88717423 0.56 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
 CYBA
 cytochrome b-245, alpha polypeptide
chr15_+_44119159 0.55 ENST00000263795.6
ENST00000381246.2
ENST00000452115.1
 WDR76
 WD repeat domain 76
chr11_+_114270752 0.55 ENST00000540163.1
 RBM7
 RNA binding motif protein 7
chr2_+_201994042 0.54 ENST00000417748.1
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr12_+_32112340 0.54 ENST00000540924.1
ENST00000312561.4
 KIAA1551
 KIAA1551
chr16_-_88717482 0.52 ENST00000261623.3
 CYBA
 cytochrome b-245, alpha polypeptide
chr19_+_36236491 0.52 ENST00000591949.1
 PSENEN
 presenilin enhancer gamma secretase subunit
chr2_+_143886877 0.52 ENST00000295095.6
 ARHGAP15
 Rho GTPase activating protein 15
chr2_-_157189180 0.51 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
 NR4A2
 nuclear receptor subfamily 4, group A, member 2
chr22_+_40342819 0.50 ENST00000407075.3
 GRAP2
 GRB2-related adaptor protein 2
chr22_+_23243156 0.50 ENST00000390323.2
 IGLC2
 immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr2_+_219247021 0.49 ENST00000539932.1
 SLC11A1
 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr17_-_40428359 0.48 ENST00000293328.3
 STAT5B
 signal transducer and activator of transcription 5B
chr6_-_84140757 0.47 ENST00000541327.1
ENST00000369705.3
ENST00000543031.1
 ME1
 malic enzyme 1, NADP(+)-dependent, cytosolic
chrX_+_16804544 0.47 ENST00000380122.5
ENST00000398155.4
 TXLNG
 taxilin gamma
chr5_-_74807418 0.47 ENST00000405807.4
ENST00000261415.7
 COL4A3BP
 collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr1_+_32716857 0.46 ENST00000482949.1
ENST00000495610.2
 LCK
 lymphocyte-specific protein tyrosine kinase
chr8_-_61193947 0.45 ENST00000317995.4
 CA8
 carbonic anhydrase VIII
chr14_-_106963409 0.44 ENST00000390621.2
 IGHV1-45
 immunoglobulin heavy variable 1-45
chr1_+_32716840 0.44 ENST00000336890.5
 LCK
 lymphocyte-specific protein tyrosine kinase
chr10_-_75226166 0.44 ENST00000544628.1
 PPP3CB
 protein phosphatase 3, catalytic subunit, beta isozyme
chr19_-_50529193 0.43 ENST00000596445.1
ENST00000599538.1
 VRK3
 vaccinia related kinase 3
chr1_+_93544791 0.42 ENST00000545708.1
ENST00000540243.1
ENST00000370298.4
 MTF2
 metal response element binding transcription factor 2
chr3_+_121554046 0.42 ENST00000273668.2
ENST00000451944.2
 EAF2
 ELL associated factor 2
chr8_+_1993173 0.42 ENST00000523438.1
 MYOM2
 myomesin 2
chrX_+_99899180 0.42 ENST00000373004.3
 SRPX2
 sushi-repeat containing protein, X-linked 2
chr1_+_93544821 0.41 ENST00000370303.4
 MTF2
 metal response element binding transcription factor 2
chr7_+_107220899 0.41 ENST00000379117.2
ENST00000473124.1
 BCAP29
 B-cell receptor-associated protein 29
chr19_+_36236514 0.41 ENST00000222266.2
 PSENEN
 presenilin enhancer gamma secretase subunit
chr11_-_28129656 0.39 ENST00000263181.6
 KIF18A
 kinesin family member 18A
chr12_+_21525818 0.39 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
 IAPP
 islet amyloid polypeptide
chr6_-_160166218 0.39 ENST00000537657.1
 SOD2
 superoxide dismutase 2, mitochondrial
chr8_+_21823726 0.38 ENST00000433566.4
 XPO7
 exportin 7
chrX_-_15872914 0.38 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
 AP1S2
 adaptor-related protein complex 1, sigma 2 subunit
chr5_+_150040403 0.37 ENST00000517768.1
ENST00000297130.4
 MYOZ3
 myozenin 3
chr1_+_26737253 0.37 ENST00000326279.6
 LIN28A
 lin-28 homolog A (C. elegans)
chr7_+_150264365 0.36 ENST00000255945.2
ENST00000461940.1
 GIMAP4
 GTPase, IMAP family member 4
chr17_-_41132410 0.36 ENST00000409446.3
ENST00000453594.1
ENST00000409399.1
ENST00000421990.2
 PTGES3L
PTGES3L-AARSD1
 prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr15_-_65903574 0.36 ENST00000420799.2
ENST00000313182.2
ENST00000431261.2
ENST00000442903.3
 VWA9
 von Willebrand factor A domain containing 9
chr19_+_50529212 0.36 ENST00000270617.3
ENST00000445728.3
ENST00000601364.1
 ZNF473
 zinc finger protein 473
chr1_-_44818599 0.36 ENST00000537474.1
 ERI3
 ERI1 exoribonuclease family member 3
chr17_+_25958174 0.36 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
 LGALS9
 lectin, galactoside-binding, soluble, 9
chr9_+_131447342 0.35 ENST00000409104.3
 SET
 SET nuclear oncogene
chr1_-_113247543 0.34 ENST00000414971.1
ENST00000534717.1
 RHOC
 ras homolog family member C
chr15_-_43559055 0.34 ENST00000220420.5
ENST00000349114.4
 TGM5
 transglutaminase 5
chr1_+_26737292 0.34 ENST00000254231.4
 LIN28A
 lin-28 homolog A (C. elegans)
chr19_+_12862604 0.34 ENST00000553030.1
 BEST2
 bestrophin 2
chr6_+_43603552 0.33 ENST00000372171.4
 MAD2L1BP
 MAD2L1 binding protein
chrX_-_53461288 0.33 ENST00000375298.4
ENST00000375304.5
 HSD17B10
 hydroxysteroid (17-beta) dehydrogenase 10
chr2_-_175870085 0.33 ENST00000409156.3
 CHN1
 chimerin 1
chr17_-_76356148 0.32 ENST00000587578.1
ENST00000330871.2
 SOCS3
 suppressor of cytokine signaling 3
chr10_+_31608054 0.32 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
 ZEB1
 zinc finger E-box binding homeobox 1
chr1_+_154975110 0.32 ENST00000535420.1
ENST00000368426.3
 ZBTB7B
 zinc finger and BTB domain containing 7B
chr1_+_199996702 0.32 ENST00000367362.3
 NR5A2
 nuclear receptor subfamily 5, group A, member 2
chr22_+_31003190 0.31 ENST00000407817.3
 TCN2
 transcobalamin II
chr2_+_178257372 0.31 ENST00000264167.4
ENST00000409888.1
 AGPS
 alkylglycerone phosphate synthase
chrX_-_53461305 0.31 ENST00000168216.6
 HSD17B10
 hydroxysteroid (17-beta) dehydrogenase 10
chr13_+_114238997 0.31 ENST00000538138.1
ENST00000375370.5
 TFDP1
 transcription factor Dp-1
chr16_-_30440530 0.31 ENST00000568434.1
 DCTPP1
 dCTP pyrophosphatase 1
chr19_+_859654 0.31 ENST00000592860.1
 CFD
 complement factor D (adipsin)
chr1_+_41445413 0.31 ENST00000541520.1
 CTPS1
 CTP synthase 1
chr11_+_236540 0.30 ENST00000532097.1
 PSMD13
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr15_-_80263506 0.30 ENST00000335661.6
 BCL2A1
 BCL2-related protein A1
chr1_-_115124257 0.30 ENST00000369541.3
 BCAS2
 breast carcinoma amplified sequence 2
chrX_+_109245863 0.30 ENST00000372072.3
 TMEM164
 transmembrane protein 164
chr7_+_73106926 0.29 ENST00000453316.1
 WBSCR22
 Williams Beuren syndrome chromosome region 22
chr16_+_27413483 0.29 ENST00000337929.3
ENST00000564089.1
 IL21R
 interleukin 21 receptor
chr3_-_167452703 0.29 ENST00000497056.2
ENST00000473645.2
 PDCD10
 programmed cell death 10
chr8_-_82395461 0.29 ENST00000256104.4
 FABP4
 fatty acid binding protein 4, adipocyte
chr2_-_40679186 0.28 ENST00000406785.2
 SLC8A1
 solute carrier family 8 (sodium/calcium exchanger), member 1
chr3_-_167452614 0.28 ENST00000392750.2
ENST00000464360.1
ENST00000492139.1
ENST00000471885.1
ENST00000470131.1
 PDCD10
 programmed cell death 10
chr17_+_48823896 0.28 ENST00000511974.1
 LUC7L3
 LUC7-like 3 (S. cerevisiae)
chr17_+_30771279 0.28 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
 PSMD11
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr2_-_175869936 0.27 ENST00000409900.3
 CHN1
 chimerin 1
chr1_-_205744205 0.27 ENST00000446390.2
 RAB7L1
 RAB7, member RAS oncogene family-like 1
chr8_+_30891298 0.27 ENST00000298139.5
 WRN
 Werner syndrome, RecQ helicase-like
chrX_-_118986911 0.27 ENST00000276201.2
ENST00000345865.2
 UPF3B
 UPF3 regulator of nonsense transcripts homolog B (yeast)
chr19_+_47634039 0.27 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
 SAE1
 SUMO1 activating enzyme subunit 1
chr11_+_237016 0.27 ENST00000352303.5
 PSMD13
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr6_-_26124138 0.26 ENST00000314332.5
ENST00000396984.1
 HIST1H2BC
 histone cluster 1, H2bc
chr19_+_50528971 0.26 ENST00000598809.1
ENST00000595661.1
ENST00000391821.2
 ZNF473
 zinc finger protein 473
chr10_-_74927810 0.26 ENST00000372979.4
ENST00000430082.2
ENST00000454759.2
ENST00000413026.1
ENST00000453402.1
 ECD
 ecdysoneless homolog (Drosophila)
chr1_-_241799232 0.26 ENST00000366553.1
 CHML
 choroideremia-like (Rab escort protein 2)
chr2_+_176972000 0.26 ENST00000249504.5
 HOXD11
 homeobox D11
chr1_-_114414316 0.25 ENST00000528414.1
ENST00000538253.1
ENST00000460620.1
ENST00000420377.2
ENST00000525799.1
ENST00000359785.5
 PTPN22
 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr22_+_31003133 0.25 ENST00000405742.3
 TCN2
 transcobalamin II
chr6_-_125623046 0.25 ENST00000608295.1
ENST00000398153.2
ENST00000608284.1
ENST00000368377.4
 HDDC2
 HD domain containing 2
chr12_-_71148413 0.25 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
 PTPRR
 protein tyrosine phosphatase, receptor type, R
chr12_-_71148357 0.25 ENST00000378778.1
 PTPRR
 protein tyrosine phosphatase, receptor type, R
chr11_+_236959 0.25 ENST00000431206.2
ENST00000528906.1
 PSMD13
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr8_+_37963311 0.25 ENST00000428278.2
ENST00000521652.1
 ASH2L
 ash2 (absent, small, or homeotic)-like (Drosophila)
chr1_+_213123976 0.25 ENST00000366965.2
ENST00000366967.2
 VASH2
 vasohibin 2
chr11_-_62432641 0.24 ENST00000528405.1
ENST00000524958.1
ENST00000525675.1
 RP11-831H9.11
C11orf48
 Uncharacterized protein
chromosome 11 open reading frame 48
chr1_-_11907829 0.24 ENST00000376480.3
 NPPA
 natriuretic peptide A
chr7_+_140373619 0.24 ENST00000483369.1
 ADCK2
 aarF domain containing kinase 2
chr7_+_77469439 0.24 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
 PHTF2
 putative homeodomain transcription factor 2
chr6_+_391739 0.23 ENST00000380956.4
 IRF4
 interferon regulatory factor 4
chr9_+_139553306 0.23 ENST00000371699.1
 EGFL7
 EGF-like-domain, multiple 7
chr2_+_201994208 0.23 ENST00000440180.1
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr15_-_65903407 0.23 ENST00000395644.4
ENST00000567744.1
ENST00000568573.1
ENST00000562830.1
ENST00000569491.1
ENST00000561769.1
 VWA9
 von Willebrand factor A domain containing 9
chr15_-_41047421 0.22 ENST00000560460.1
ENST00000338376.3
ENST00000560905.1
 RMDN3
 regulator of microtubule dynamics 3
chr19_+_859425 0.22 ENST00000327726.6
 CFD
 complement factor D (adipsin)
chrX_+_77166172 0.22 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
 ATP7A
 ATPase, Cu++ transporting, alpha polypeptide
chr5_+_176853702 0.22 ENST00000507633.1
ENST00000393576.3
ENST00000355958.5
ENST00000528793.1
ENST00000512684.1
 GRK6
 G protein-coupled receptor kinase 6
chr7_+_140372953 0.22 ENST00000072869.4
ENST00000476491.1
 ADCK2
 aarF domain containing kinase 2
chr6_+_35996859 0.22 ENST00000472333.1
 MAPK14
 mitogen-activated protein kinase 14
chr9_+_131452239 0.21 ENST00000372688.4
ENST00000372686.5
 SET
 SET nuclear oncogene
chr6_-_13487784 0.21 ENST00000379287.3
 GFOD1
 glucose-fructose oxidoreductase domain containing 1
chr10_-_65028938 0.21 ENST00000402544.1
 JMJD1C
 jumonji domain containing 1C
chr2_+_58134756 0.21 ENST00000435505.2
ENST00000417641.2
 VRK2
 vaccinia related kinase 2
chr8_+_56014949 0.21 ENST00000327381.6
 XKR4
 XK, Kell blood group complex subunit-related family, member 4
chr17_-_15165854 0.21 ENST00000395936.1
ENST00000395938.2
 PMP22
 peripheral myelin protein 22
chrX_-_119709637 0.20 ENST00000404115.3
 CUL4B
 cullin 4B
chr1_-_154832316 0.20 ENST00000361147.4
 KCNN3
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr6_+_127588020 0.20 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
 RNF146
 ring finger protein 146
chr6_-_112194484 0.20 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
 FYN
 FYN oncogene related to SRC, FGR, YES
chr11_-_236326 0.20 ENST00000525237.1
ENST00000532956.1
ENST00000525319.1
ENST00000524564.1
ENST00000382743.4
 SIRT3
 sirtuin 3
chr16_-_4395905 0.20 ENST00000571941.1
 PAM16
 presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr22_+_23522552 0.20 ENST00000359540.3
ENST00000398512.5
 BCR
 breakpoint cluster region
chr17_-_42345487 0.20 ENST00000262418.6
 SLC4A1
 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
chr1_+_89829610 0.20 ENST00000370456.4
ENST00000535065.1
 GBP6
 guanylate binding protein family, member 6
chr12_+_57853918 0.20 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
 GLI1
 GLI family zinc finger 1
chr5_-_176433350 0.20 ENST00000377227.4
ENST00000377219.2
 UIMC1
 ubiquitin interaction motif containing 1
chr7_+_141438393 0.19 ENST00000484178.1
ENST00000473783.1
ENST00000481508.1
 SSBP1
 single-stranded DNA binding protein 1, mitochondrial
chrX_+_129473859 0.19 ENST00000424447.1
 SLC25A14
 solute carrier family 25 (mitochondrial carrier, brain), member 14
chr17_+_9066252 0.19 ENST00000436734.1
 NTN1
 netrin 1
chrX_+_129473916 0.19 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
 SLC25A14
 solute carrier family 25 (mitochondrial carrier, brain), member 14
chr1_-_46598284 0.19 ENST00000423209.1
ENST00000262741.5
 PIK3R3
 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr17_+_25799008 0.19 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
 KSR1
 kinase suppressor of ras 1
chr11_+_64073699 0.19 ENST00000405666.1
ENST00000468670.1
 ESRRA
 estrogen-related receptor alpha
chr17_+_46184911 0.18 ENST00000580219.1
ENST00000452859.2
ENST00000393405.2
ENST00000439357.2
ENST00000359238.2
 SNX11
 sorting nexin 11
chr12_+_12938541 0.18 ENST00000356591.4
 APOLD1
 apolipoprotein L domain containing 1
chr11_-_615570 0.18 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
 IRF7
 interferon regulatory factor 7
chr15_+_63796779 0.18 ENST00000561442.1
ENST00000560070.1
ENST00000540797.1
ENST00000380324.3
ENST00000268049.7
ENST00000536001.1
ENST00000539772.1
 USP3
 ubiquitin specific peptidase 3
chr2_-_61697862 0.18 ENST00000398571.2
 USP34
 ubiquitin specific peptidase 34
chr12_+_75874984 0.18 ENST00000550491.1
 GLIPR1
 GLI pathogenesis-related 1
chr10_-_76868931 0.18 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
 DUSP13
 dual specificity phosphatase 13
chr4_+_160188889 0.18 ENST00000264431.4
 RAPGEF2
 Rap guanine nucleotide exchange factor (GEF) 2
chr6_-_46922659 0.18 ENST00000265417.7
 GPR116
 G protein-coupled receptor 116
chr2_-_25391507 0.18 ENST00000380794.1
 POMC
 proopiomelanocortin
chr8_+_38585704 0.18 ENST00000519416.1
ENST00000520615.1
 TACC1
 transforming, acidic coiled-coil containing protein 1
chr9_+_134378289 0.18 ENST00000423007.1
ENST00000404875.2
ENST00000441334.1
ENST00000341012.7
ENST00000372228.3
ENST00000402686.3
ENST00000419118.2
ENST00000541219.1
ENST00000354713.4
ENST00000418774.1
ENST00000415075.1
ENST00000448212.1
ENST00000430619.1
 POMT1
 protein-O-mannosyltransferase 1
chr12_-_7848364 0.18 ENST00000329913.3
 GDF3
 growth differentiation factor 3
chr3_+_157828152 0.18 ENST00000476899.1
 RSRC1
 arginine/serine-rich coiled-coil 1
chr7_+_107384142 0.17 ENST00000440859.3
 CBLL1
 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr1_-_46598371 0.17 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
 PIK3R3
 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr6_+_39760129 0.17 ENST00000274867.4
 DAAM2
 dishevelled associated activator of morphogenesis 2
chr9_+_90112117 0.17 ENST00000358077.5
 DAPK1
 death-associated protein kinase 1
chr10_+_95256356 0.17 ENST00000371485.3
 CEP55
 centrosomal protein 55kDa
chr15_+_60296421 0.17 ENST00000396057.4
 FOXB1
 forkhead box B1
chr8_-_42623747 0.17 ENST00000534622.1
 CHRNA6
 cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr9_-_127177703 0.17 ENST00000259457.3
ENST00000536392.1
ENST00000441097.1
 PSMB7
 proteasome (prosome, macropain) subunit, beta type, 7
chr8_-_124428569 0.17 ENST00000521903.1
 ATAD2
 ATPase family, AAA domain containing 2
chr6_+_30312908 0.17 ENST00000433076.2
ENST00000442966.2
ENST00000428040.2
ENST00000436442.2
 RPP21
 ribonuclease P/MRP 21kDa subunit
chr9_-_132805430 0.17 ENST00000446176.2
ENST00000355681.3
ENST00000420781.1
 FNBP1
 formin binding protein 1
chr3_-_125094093 0.17 ENST00000484491.1
ENST00000492394.1
ENST00000471196.1
ENST00000468369.1
ENST00000544464.1
ENST00000485866.1
ENST00000360647.4
 ZNF148
 zinc finger protein 148
chr3_-_197024394 0.17 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
 DLG1
 discs, large homolog 1 (Drosophila)
chr7_-_91875358 0.16 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
 KRIT1
 KRIT1, ankyrin repeat containing
chr2_-_242088850 0.16 ENST00000358649.4
ENST00000452907.1
ENST00000403638.3
ENST00000539818.1
ENST00000415234.1
ENST00000234040.4
 PASK
 PAS domain containing serine/threonine kinase
chr1_-_160313025 0.16 ENST00000368069.3
ENST00000241704.7
 COPA
 coatomer protein complex, subunit alpha
chr5_+_64859066 0.16 ENST00000261308.5
ENST00000535264.1
ENST00000538977.1
 PPWD1
 peptidylprolyl isomerase domain and WD repeat containing 1
chr22_-_31688381 0.16 ENST00000487265.2
 PIK3IP1
 phosphoinositide-3-kinase interacting protein 1
chr8_-_42623924 0.16 ENST00000276410.2
 CHRNA6
 cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr5_+_154320623 0.16 ENST00000523037.1
ENST00000265229.8
ENST00000439747.3
ENST00000522038.1
 MRPL22
 mitochondrial ribosomal protein L22

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.6 1.7 GO:0043132 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132)
0.4 1.2 GO:0061010 gall bladder development(GO:0061010)
0.3 2.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.3 1.3 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.2 0.7 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 1.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 0.7 GO:2000525 dendritic cell dendrite assembly(GO:0097026) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.2 0.6 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.2 0.6 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.2 0.5 GO:0055073 cadmium ion homeostasis(GO:0055073)
0.2 0.5 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2 1.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 0.5 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 0.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.4 GO:0032831 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.1 0.8 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.9 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 1.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.5 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.5 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.6 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.8 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 0.6 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.3 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.6 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.3 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.5 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.8 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.2 GO:0045082 interleukin-4 biosynthetic process(GO:0042097) positive regulation of interleukin-10 biosynthetic process(GO:0045082) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.4 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.8 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.4 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.2 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.2 GO:1901189 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 1.1 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.8 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.2 GO:0021938 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.1 0.5 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.7 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.3 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.1 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.2 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.9 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.2 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 1.3 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.2 GO:0061030 axon target recognition(GO:0007412) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.3 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.3 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.6 GO:0008228 opsonization(GO:0008228)
0.0 0.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.4 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.2 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 1.9 GO:0002820 negative regulation of adaptive immune response(GO:0002820)
0.0 0.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:1903464 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) negative regulation of mitotic cell cycle DNA replication(GO:1903464) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.2 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.2 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.1 GO:0002155 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 2.1 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425) valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:0043449 olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.0 0.1 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.1 GO:0035962 response to interleukin-13(GO:0035962)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.2 GO:1902302 regulation of potassium ion export(GO:1902302)
0.0 0.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.4 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.2 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0 0.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.6 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.2 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 1.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.3 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.3 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 0.0 GO:1905071 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.2 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.0 GO:0015965 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.0 0.2 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.0 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.0 0.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.4 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.0 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.3 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0032006 regulation of TOR signaling(GO:0032006)
0.0 0.1 GO:0045794 negative regulation of cell volume(GO:0045794)
0.0 0.1 GO:0090312 positive regulation of protein deacetylation(GO:0090312)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0032060 bleb assembly(GO:0032060)
0.0 0.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 1.2 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.1 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.4 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.0 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.5 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.2 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 1.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.1 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.1 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0044326 dendritic spine neck(GO:0044326)
0.1 0.9 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.6 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 2.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.6 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 1.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.6 GO:0031415 NatA complex(GO:0031415)
0.1 1.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.3 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.8 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.9 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.4 GO:1990023 kinetochore microtubule(GO:0005828) mitotic spindle midzone(GO:1990023)
0.0 0.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.6 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 2.3 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.1 GO:0033010 paranodal junction(GO:0033010)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0051185 FAD transmembrane transporter activity(GO:0015230) coenzyme transporter activity(GO:0051185)
0.3 0.8 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 0.6 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.2 1.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.2 0.5 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.1 2.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.5 GO:0097001 ceramide binding(GO:0097001)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.5 GO:0008948 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.1 0.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.4 GO:0051373 FATZ binding(GO:0051373)
0.1 1.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 1.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.7 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 0.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.2 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.3 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.6 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819) valine-tRNA ligase activity(GO:0004832)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 2.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.5 GO:0097493 muscle alpha-actinin binding(GO:0051371) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0071949 FAD binding(GO:0071949)
0.0 0.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.0 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 2.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.2 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID EPO PATHWAY EPO signaling pathway