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ENCODE cell lines, expression (Ernst 2011)

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Results for TCF7

Z-value: 1.15

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Transcription factors associated with TCF7

Gene Symbol Gene ID Gene Info
TCF7
ENSG00000081059.15 TCF7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7hg19_v2_chr5_+_133477905_133477956-0.765.8e-04Click!

Activity profile of TCF7 motif

Sorted Z-values of TCF7 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_151344172 7.50 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
 RND3
 Rho family GTPase 3
chr10_+_54074033 4.34 ENST00000373970.3
 DKK1
 dickkopf WNT signaling pathway inhibitor 1
chr7_+_94023873 3.74 ENST00000297268.6
 COL1A2
 collagen, type I, alpha 2
chr12_+_6309963 3.67 ENST00000382515.2
 CD9
 CD9 molecule
chr5_+_34757309 3.60 ENST00000397449.1
 RAI14
 retinoic acid induced 14
chr8_-_119964434 3.56 ENST00000297350.4
 TNFRSF11B
 tumor necrosis factor receptor superfamily, member 11b
chr5_-_16936340 3.07 ENST00000507288.1
ENST00000513610.1
 MYO10
 myosin X
chr3_+_159570722 2.65 ENST00000482804.1
 SCHIP1
 schwannomin interacting protein 1
chr15_+_74218787 2.53 ENST00000261921.7
 LOXL1
 lysyl oxidase-like 1
chr7_-_80548667 2.44 ENST00000265361.3
 SEMA3C
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_+_135364584 2.26 ENST00000442011.2
ENST00000305126.8
 TGFBI
 transforming growth factor, beta-induced, 68kDa
chr7_-_107643674 2.17 ENST00000222399.6
 LAMB1
 laminin, beta 1
chr1_-_79472365 2.15 ENST00000370742.3
 ELTD1
 EGF, latrophilin and seven transmembrane domain containing 1
chr14_+_85996471 2.15 ENST00000330753.4
 FLRT2
 fibronectin leucine rich transmembrane protein 2
chr9_-_35691017 2.04 ENST00000378292.3
 TPM2
 tropomyosin 2 (beta)
chr7_+_134576317 2.01 ENST00000424922.1
ENST00000495522.1
 CALD1
 caldesmon 1
chr9_-_130639997 1.96 ENST00000373176.1
 AK1
 adenylate kinase 1
chr5_-_157002775 1.87 ENST00000257527.4
 ADAM19
 ADAM metallopeptidase domain 19
chr10_+_17271266 1.79 ENST00000224237.5
 VIM
 vimentin
chr2_+_234621551 1.78 ENST00000608381.1
ENST00000373414.3
 UGT1A1
UGT1A5
 UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr7_+_130131907 1.78 ENST00000223215.4
ENST00000437945.1
 MEST
 mesoderm specific transcript
chr8_+_30244580 1.74 ENST00000523115.1
ENST00000519647.1
 RBPMS
 RNA binding protein with multiple splicing
chr7_+_134576151 1.72 ENST00000393118.2
 CALD1
 caldesmon 1
chr13_+_102142296 1.64 ENST00000376162.3
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr2_-_217560248 1.61 ENST00000233813.4
 IGFBP5
 insulin-like growth factor binding protein 5
chr1_-_110933663 1.58 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
 SLC16A4
 solute carrier family 16, member 4
chr1_-_110933611 1.50 ENST00000472422.2
ENST00000437429.2
 SLC16A4
 solute carrier family 16, member 4
chr13_+_102104980 1.45 ENST00000545560.2
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr6_+_83073334 1.43 ENST00000369750.3
 TPBG
 trophoblast glycoprotein
chr4_-_52904425 1.43 ENST00000535450.1
 SGCB
 sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr17_-_46623441 1.39 ENST00000330070.4
 HOXB2
 homeobox B2
chr13_+_102104952 1.37 ENST00000376180.3
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr6_-_112575912 1.37 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
 LAMA4
 laminin, alpha 4
chr3_+_138067521 1.33 ENST00000494949.1
 MRAS
 muscle RAS oncogene homolog
chrX_+_51927919 1.25 ENST00000416960.1
 MAGED4
 melanoma antigen family D, 4
chr12_-_10022735 1.25 ENST00000228438.2
 CLEC2B
 C-type lectin domain family 2, member B
chr6_+_83073952 1.21 ENST00000543496.1
 TPBG
 trophoblast glycoprotein
chr6_-_112575687 1.20 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
 LAMA4
 laminin, alpha 4
chr8_-_145047688 1.19 ENST00000356346.3
 PLEC
 plectin
chr7_-_27213893 1.18 ENST00000283921.4
 HOXA10
 homeobox A10
chr22_+_39052632 1.14 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
 CBY1
 chibby homolog 1 (Drosophila)
chr14_+_85996507 1.13 ENST00000554746.1
 FLRT2
 fibronectin leucine rich transmembrane protein 2
chr9_+_124088860 1.12 ENST00000373806.1
 GSN
 gelsolin
chr4_-_7873981 1.05 ENST00000360265.4
 AFAP1
 actin filament associated protein 1
chr12_+_21654714 1.01 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
 GOLT1B
 golgi transport 1B
chr7_+_23286182 0.99 ENST00000258733.4
ENST00000381990.2
ENST00000409458.3
ENST00000539136.1
ENST00000453162.2
 GPNMB
 glycoprotein (transmembrane) nmb
chr2_+_46926326 0.98 ENST00000394861.2
 SOCS5
 suppressor of cytokine signaling 5
chr2_+_189157536 0.93 ENST00000409580.1
ENST00000409637.3
 GULP1
 GULP, engulfment adaptor PTB domain containing 1
chr2_-_36825281 0.92 ENST00000405912.3
ENST00000379245.4
 FEZ2
 fasciculation and elongation protein zeta 2 (zygin II)
chr4_+_87515454 0.91 ENST00000427191.2
ENST00000436978.1
ENST00000502971.1
 PTPN13
 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
chr1_-_209824643 0.91 ENST00000391911.1
ENST00000415782.1
 LAMB3
 laminin, beta 3
chr2_-_231989808 0.90 ENST00000258400.3
 HTR2B
 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr4_+_154125565 0.88 ENST00000338700.5
 TRIM2
 tripartite motif containing 2
chr17_-_7297519 0.84 ENST00000576362.1
ENST00000571078.1
 TMEM256-PLSCR3
 TMEM256-PLSCR3 readthrough (NMD candidate)
chr11_-_33774944 0.84 ENST00000532057.1
ENST00000531080.1
 FBXO3
 F-box protein 3
chr2_+_69240302 0.83 ENST00000303714.4
 ANTXR1
 anthrax toxin receptor 1
chr6_-_112575838 0.83 ENST00000455073.1
 LAMA4
 laminin, alpha 4
chr18_+_3449821 0.80 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
 TGIF1
 TGFB-induced factor homeobox 1
chr8_-_101962777 0.79 ENST00000395951.3
 YWHAZ
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chrX_+_54835493 0.78 ENST00000396224.1
 MAGED2
 melanoma antigen family D, 2
chr14_+_74486043 0.76 ENST00000464394.1
ENST00000394009.3
 CCDC176
 coiled-coil domain containing 176
chrX_+_12993336 0.76 ENST00000380635.1
 TMSB4X
 thymosin beta 4, X-linked
chr9_+_125137565 0.74 ENST00000373698.5
 PTGS1
 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr9_-_132586378 0.73 ENST00000351698.4
 TOR1A
 torsin family 1, member A (torsin A)
chr6_+_52285046 0.72 ENST00000371068.5
 EFHC1
 EF-hand domain (C-terminal) containing 1
chr1_-_151345159 0.70 ENST00000458566.1
ENST00000447402.3
ENST00000426705.2
ENST00000435071.1
ENST00000368868.5
 SELENBP1
 selenium binding protein 1
chr4_-_129209944 0.69 ENST00000520121.1
 PGRMC2
 progesterone receptor membrane component 2
chr11_+_65339820 0.68 ENST00000316409.2
ENST00000449319.2
ENST00000530349.1
 FAM89B
 family with sequence similarity 89, member B
chr11_+_7506713 0.67 ENST00000329293.3
ENST00000534244.1
 OLFML1
 olfactomedin-like 1
chr13_-_36920872 0.67 ENST00000451493.1
 SPG20
 spastic paraplegia 20 (Troyer syndrome)
chr6_-_112575758 0.65 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
 LAMA4
 laminin, alpha 4
chr13_-_36920615 0.65 ENST00000494062.2
 SPG20
 spastic paraplegia 20 (Troyer syndrome)
chr19_+_1026566 0.62 ENST00000348419.3
ENST00000565096.2
ENST00000562958.2
ENST00000562075.2
ENST00000607102.1
 CNN2
 calponin 2
chr16_+_68678739 0.61 ENST00000264012.4
 CDH3
 cadherin 3, type 1, P-cadherin (placental)
chr8_-_98290087 0.59 ENST00000322128.3
 TSPYL5
 TSPY-like 5
chr2_-_208031943 0.59 ENST00000421199.1
ENST00000457962.1
 KLF7
 Kruppel-like factor 7 (ubiquitous)
chr13_-_36920420 0.58 ENST00000438666.2
 SPG20
 spastic paraplegia 20 (Troyer syndrome)
chr15_+_74466012 0.57 ENST00000249842.3
 ISLR
 immunoglobulin superfamily containing leucine-rich repeat
chr5_-_157002749 0.57 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
 ADAM19
 ADAM metallopeptidase domain 19
chrX_-_13956737 0.55 ENST00000454189.2
 GPM6B
 glycoprotein M6B
chrX_+_102883620 0.52 ENST00000372626.3
 TCEAL1
 transcription elongation factor A (SII)-like 1
chrX_+_12993202 0.51 ENST00000451311.2
ENST00000380636.1
 TMSB4X
 thymosin beta 4, X-linked
chr11_-_65625678 0.51 ENST00000308162.5
 CFL1
 cofilin 1 (non-muscle)
chr5_-_140700322 0.50 ENST00000313368.5
 TAF7
 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
chr2_+_181845298 0.49 ENST00000410062.4
 UBE2E3
 ubiquitin-conjugating enzyme E2E 3
chr21_+_39628852 0.46 ENST00000398938.2
 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_68150744 0.46 ENST00000370986.4
ENST00000370985.3
 GADD45A
 growth arrest and DNA-damage-inducible, alpha
chr10_-_49860525 0.46 ENST00000435790.2
 ARHGAP22
 Rho GTPase activating protein 22
chr11_-_64013663 0.46 ENST00000392210.2
 PPP1R14B
 protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr17_-_79818354 0.45 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
 P4HB
 prolyl 4-hydroxylase, beta polypeptide
chr1_-_161993616 0.45 ENST00000294794.3
 OLFML2B
 olfactomedin-like 2B
chr19_+_1026298 0.43 ENST00000263097.4
 CNN2
 calponin 2
chr9_+_91003271 0.42 ENST00000375859.3
ENST00000541629.1
 SPIN1
 spindlin 1
chr12_+_4714145 0.42 ENST00000545342.1
 DYRK4
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr19_+_45281118 0.41 ENST00000270279.3
ENST00000341505.4
 CBLC
 Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr8_-_17579726 0.41 ENST00000381861.3
 MTUS1
 microtubule associated tumor suppressor 1
chr3_+_35681081 0.40 ENST00000428373.1
 ARPP21
 cAMP-regulated phosphoprotein, 21kDa
chr13_+_29233218 0.39 ENST00000380842.4
 POMP
 proteasome maturation protein
chr9_+_125703282 0.38 ENST00000373647.4
ENST00000402311.1
 RABGAP1
 RAB GTPase activating protein 1
chr17_-_26989136 0.38 ENST00000247020.4
 SDF2
 stromal cell-derived factor 2
chrX_+_135618258 0.37 ENST00000440515.1
ENST00000456412.1
 VGLL1
 vestigial like 1 (Drosophila)
chr1_-_16345245 0.37 ENST00000311890.9
 HSPB7
 heat shock 27kDa protein family, member 7 (cardiovascular)
chrX_-_106960285 0.37 ENST00000503515.1
ENST00000372397.2
 TSC22D3
 TSC22 domain family, member 3
chr5_-_148930960 0.37 ENST00000261798.5
ENST00000377843.2
 CSNK1A1
 casein kinase 1, alpha 1
chr2_+_10183651 0.36 ENST00000305883.1
 KLF11
 Kruppel-like factor 11
chr12_-_133405288 0.36 ENST00000204726.3
 GOLGA3
 golgin A3
chr3_+_36421826 0.36 ENST00000273183.3
 STAC
 SH3 and cysteine rich domain
chrX_-_148676974 0.35 ENST00000524178.1
 HSFX2
 heat shock transcription factor family, X linked 2
chr10_+_52750930 0.34 ENST00000401604.2
 PRKG1
 protein kinase, cGMP-dependent, type I
chr22_+_19950060 0.34 ENST00000449653.1
 COMT
 catechol-O-methyltransferase
chr1_-_153113927 0.34 ENST00000368752.4
 SPRR2B
 small proline-rich protein 2B
chr21_+_39628655 0.33 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
chr3_+_111717600 0.33 ENST00000273368.4
 TAGLN3
 transgelin 3
chr3_-_125775629 0.33 ENST00000383598.2
 SLC41A3
 solute carrier family 41, member 3
chr2_-_86564776 0.33 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
 REEP1
 receptor accessory protein 1
chr8_+_73921085 0.32 ENST00000276603.5
ENST00000276602.6
ENST00000518874.1
 TERF1
 telomeric repeat binding factor (NIMA-interacting) 1
chr13_+_45694583 0.31 ENST00000340473.6
 GTF2F2
 general transcription factor IIF, polypeptide 2, 30kDa
chr5_-_82969405 0.31 ENST00000510978.1
 HAPLN1
 hyaluronan and proteoglycan link protein 1
chr9_-_100459639 0.31 ENST00000375128.4
 XPA
 xeroderma pigmentosum, complementation group A
chr17_+_48610074 0.31 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
 EPN3
 epsin 3
chr6_+_125540951 0.31 ENST00000524679.1
 TPD52L1
 tumor protein D52-like 1
chr3_+_111717511 0.31 ENST00000478951.1
ENST00000393917.2
 TAGLN3
 transgelin 3
chr12_-_6055398 0.31 ENST00000327087.8
ENST00000356134.5
ENST00000546188.1
 ANO2
 anoctamin 2
chrX_+_148855726 0.31 ENST00000370416.4
 HSFX1
 heat shock transcription factor family, X linked 1
chr19_+_13135386 0.31 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
 NFIX
 nuclear factor I/X (CCAAT-binding transcription factor)
chr12_-_10151773 0.30 ENST00000298527.6
ENST00000348658.4
 CLEC1B
 C-type lectin domain family 1, member B
chr1_-_153013588 0.30 ENST00000360379.3
 SPRR2D
 small proline-rich protein 2D
chr20_+_31823792 0.30 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
 BPIFA1
 BPI fold containing family A, member 1
chr4_+_159593271 0.30 ENST00000512251.1
ENST00000511912.1
 ETFDH
 electron-transferring-flavoprotein dehydrogenase
chr14_+_61201445 0.30 ENST00000261245.4
ENST00000539616.2
 MNAT1
 MNAT CDK-activating kinase assembly factor 1
chr10_+_52833883 0.29 ENST00000373980.4
 PRKG1
 protein kinase, cGMP-dependent, type I
chr19_+_58898627 0.29 ENST00000598098.1
ENST00000598495.1
ENST00000196551.3
ENST00000596046.1
 RPS5
 ribosomal protein S5
chrX_+_100663243 0.28 ENST00000316594.5
 HNRNPH2
 heterogeneous nuclear ribonucleoprotein H2 (H')
chr5_+_140165876 0.28 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
 PCDHA1
 protocadherin alpha 1
chr7_+_80231466 0.27 ENST00000309881.7
ENST00000534394.1
 CD36
 CD36 molecule (thrombospondin receptor)
chr9_-_21187598 0.27 ENST00000421715.1
 IFNA4
 interferon, alpha 4
chr2_+_234580525 0.27 ENST00000609637.1
 UGT1A1
 UDP glucuronosyltransferase 1 family, polypeptide A8
chr6_-_32145861 0.26 ENST00000336984.6
 AGPAT1
 1-acylglycerol-3-phosphate O-acyltransferase 1
chr11_-_122930121 0.25 ENST00000524552.1
 HSPA8
 heat shock 70kDa protein 8
chr19_+_42829702 0.25 ENST00000334370.4
 MEGF8
 multiple EGF-like-domains 8
chr17_-_37009882 0.24 ENST00000378096.3
ENST00000394332.1
ENST00000394333.1
ENST00000577407.1
ENST00000479035.2
 RPL23
 ribosomal protein L23
chr19_+_41256764 0.24 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
 SNRPA
 small nuclear ribonucleoprotein polypeptide A
chr2_+_234580499 0.23 ENST00000354728.4
 UGT1A9
 UDP glucuronosyltransferase 1 family, polypeptide A9
chrX_-_55020511 0.23 ENST00000375006.3
ENST00000374992.2
 PFKFB1
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr8_-_20161466 0.23 ENST00000381569.1
 LZTS1
 leucine zipper, putative tumor suppressor 1
chr3_-_126327398 0.22 ENST00000383572.2
 TXNRD3NB
 thioredoxin reductase 3 neighbor
chrX_-_153599578 0.22 ENST00000360319.4
ENST00000344736.4
 FLNA
 filamin A, alpha
chr3_+_118892362 0.22 ENST00000497685.1
ENST00000264234.3
 UPK1B
 uroplakin 1B
chr2_+_46926048 0.21 ENST00000306503.5
 SOCS5
 suppressor of cytokine signaling 5
chr1_-_153029980 0.21 ENST00000392653.2
 SPRR2A
 small proline-rich protein 2A
chr4_-_74486347 0.20 ENST00000342081.3
 RASSF6
 Ras association (RalGDS/AF-6) domain family member 6
chr11_-_64013288 0.20 ENST00000542235.1
 PPP1R14B
 protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_+_27593389 0.20 ENST00000233575.2
ENST00000543024.1
ENST00000537606.1
 SNX17
 sorting nexin 17
chr22_+_39077947 0.20 ENST00000216034.4
 TOMM22
 translocase of outer mitochondrial membrane 22 homolog (yeast)
chr14_+_101299520 0.19 ENST00000455531.1
 MEG3
 maternally expressed 3 (non-protein coding)
chr11_-_6677018 0.18 ENST00000299441.3
 DCHS1
 dachsous cadherin-related 1
chr7_+_55086703 0.18 ENST00000455089.1
ENST00000342916.3
ENST00000344576.2
ENST00000420316.2
 EGFR
 epidermal growth factor receptor
chr4_-_139163491 0.18 ENST00000280612.5
 SLC7A11
 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr5_+_140579162 0.17 ENST00000536699.1
ENST00000354757.3
 PCDHB11
 protocadherin beta 11
chr17_-_17485731 0.17 ENST00000395783.1
 PEMT
 phosphatidylethanolamine N-methyltransferase
chr10_+_99332198 0.17 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
 ANKRD2
 ankyrin repeat domain 2 (stretch responsive muscle)
chr1_-_211752073 0.17 ENST00000367001.4
 SLC30A1
 solute carrier family 30 (zinc transporter), member 1
chr3_-_167813672 0.16 ENST00000470487.1
 GOLIM4
 golgi integral membrane protein 4
chr11_-_10829851 0.16 ENST00000532082.1
 EIF4G2
 eukaryotic translation initiation factor 4 gamma, 2
chr19_-_54746600 0.16 ENST00000245621.5
ENST00000270464.5
ENST00000419410.2
ENST00000391735.3
ENST00000396365.2
ENST00000440558.2
ENST00000407860.2
 LILRA6
LILRB3
 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
chr22_-_42526802 0.15 ENST00000359033.4
ENST00000389970.3
ENST00000360608.5
 CYP2D6
 cytochrome P450, family 2, subfamily D, polypeptide 6
chr1_-_149900122 0.15 ENST00000271628.8
 SF3B4
 splicing factor 3b, subunit 4, 49kDa
chr2_-_136288113 0.14 ENST00000401392.1
 ZRANB3
 zinc finger, RAN-binding domain containing 3
chr5_-_137610300 0.14 ENST00000274721.3
 GFRA3
 GDNF family receptor alpha 3
chr9_-_127533519 0.14 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
 NR6A1
 nuclear receptor subfamily 6, group A, member 1
chr3_+_111718036 0.13 ENST00000455401.2
 TAGLN3
 transgelin 3
chr12_-_89920030 0.13 ENST00000413530.1
ENST00000547474.1
 GALNT4
POC1B-GALNT4
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr7_-_142207004 0.13 ENST00000426318.2
 TRBV10-2
 T cell receptor beta variable 10-2
chr2_-_27593306 0.12 ENST00000347454.4
 EIF2B4
 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
chr11_+_113848216 0.12 ENST00000299961.5
 HTR3A
 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
chr19_+_57791419 0.12 ENST00000537645.1
 ZNF460
 zinc finger protein 460
chr15_+_52043758 0.12 ENST00000249700.4
ENST00000539962.2
 TMOD2
 tropomodulin 2 (neuronal)
chr1_+_59762642 0.11 ENST00000371218.4
ENST00000303721.7
 FGGY
 FGGY carbohydrate kinase domain containing
chr11_-_10830463 0.11 ENST00000527419.1
ENST00000530211.1
ENST00000530702.1
ENST00000524932.1
ENST00000532570.1
 EIF4G2
 eukaryotic translation initiation factor 4 gamma, 2
chr8_+_133879193 0.11 ENST00000377869.1
ENST00000220616.4
 TG
 thyroglobulin
chr8_-_6914251 0.11 ENST00000330590.2
 DEFA5
 defensin, alpha 5, Paneth cell-specific
chr22_-_37880543 0.10 ENST00000442496.1
 MFNG
 MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr5_-_137610254 0.10 ENST00000378362.3
 GFRA3
 GDNF family receptor alpha 3
chr4_-_159080806 0.09 ENST00000590648.1
 FAM198B
 family with sequence similarity 198, member B
chr17_-_56065484 0.09 ENST00000581208.1
 VEZF1
 vascular endothelial zinc finger 1
chr4_-_5891918 0.09 ENST00000512574.1
 CRMP1
 collapsin response mediator protein 1
chr19_-_40791211 0.08 ENST00000579047.1
 AKT2
 v-akt murine thymoma viral oncogene homolog 2
chr12_+_27677085 0.08 ENST00000545334.1
ENST00000540114.1
ENST00000537927.1
ENST00000318304.8
ENST00000535047.1
ENST00000542629.1
ENST00000228425.6
 PPFIBP1
 PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr3_-_197676740 0.08 ENST00000452735.1
ENST00000453254.1
ENST00000455191.1
 IQCG
 IQ motif containing G
chr5_-_157286104 0.08 ENST00000530742.1
ENST00000523908.1
ENST00000523094.1
ENST00000296951.5
ENST00000411809.2
 CLINT1
 clathrin interactor 1
chr14_+_21214039 0.08 ENST00000326842.2
 EDDM3A
 epididymal protein 3A
chr1_+_10459111 0.08 ENST00000541529.1
ENST00000270776.8
ENST00000483936.1
ENST00000538557.1
 PGD
 phosphogluconate dehydrogenase
chr2_+_1417228 0.07 ENST00000382269.3
ENST00000337415.3
ENST00000345913.4
ENST00000346956.3
ENST00000349624.3
ENST00000539820.1
ENST00000329066.4
ENST00000382201.3
 TPO
 thyroid peroxidase
chr11_-_129062093 0.07 ENST00000310343.9
 ARHGAP32
 Rho GTPase activating protein 32
chr9_-_125675576 0.07 ENST00000373659.3
 ZBTB6
 zinc finger and BTB domain containing 6
chr20_-_17511962 0.06 ENST00000377873.3
 BFSP1
 beaded filament structural protein 1, filensin
chr8_+_145064215 0.06 ENST00000313269.5
 GRINA
 glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr2_+_7017796 0.06 ENST00000382040.3
 RSAD2
 radical S-adenosyl methionine domain containing 2
chrX_-_102757802 0.06 ENST00000372633.1
 RAB40A
 RAB40A, member RAS oncogene family
chr2_-_166060571 0.06 ENST00000360093.3
 SCN3A
 sodium channel, voltage-gated, type III, alpha subunit

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.3 0.9 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 1.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 1.0 GO:0031905 early endosome lumen(GO:0031905)
0.2 0.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 0.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 0.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.7 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.9 GO:0001939 female pronucleus(GO:0001939)
0.1 0.8 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.9 GO:0031010 ISWI-type complex(GO:0031010)
0.1 1.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.2 GO:0044094 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.1 0.6 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 0.5 GO:0005638 lamin filament(GO:0005638)
0.0 0.7 GO:0001741 XY body(GO:0001741)
0.0 0.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.8 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 7.2 GO:0072562 blood microparticle(GO:0072562)
0.0 1.5 GO:0016235 aggresome(GO:0016235)
0.0 1.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 1.0 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.5 GO:0031105 septin complex(GO:0031105)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0045120 pronucleus(GO:0045120)
0.0 0.2 GO:1990909 catenin complex(GO:0016342) Wnt signalosome(GO:1990909)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.9 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.4 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 5.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 10.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 4.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 4.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 2.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 5.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 11.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 5.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
1.6 4.8 GO:0009996 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996) Wnt signaling pathway involved in somitogenesis(GO:0090244)
1.2 4.7 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
1.1 6.6 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.7 6.5 GO:0070141 response to UV-A(GO:0070141)
0.6 2.3 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.6 2.8 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.5 1.5 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.5 6.0 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.4 5.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.4 0.8 GO:1904833 positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.3 2.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.3 0.9 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.3 1.8 GO:2000334 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.3 0.8 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787) response to antineoplastic agent(GO:0097327)
0.2 0.7 GO:0061055 myotome development(GO:0061055) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2 0.7 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.2 5.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.2 10.0 GO:0035329 hippo signaling(GO:0035329)
0.2 0.7 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 10.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 1.0 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.7 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 1.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 1.0 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 1.4 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 2.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 1.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 1.0 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 3.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072) positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.2 GO:0016036 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 5.8 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.4 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.8 GO:0016574 histone ubiquitination(GO:0016574)
0.0 10.0 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 3.0 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 3.8 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.3 GO:0032196 transposition(GO:0032196)
0.0 1.3 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.6 GO:0001885 endothelial cell development(GO:0001885)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996) Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.9 3.6 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.5 3.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.5 2.2 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.5 1.6 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.5 1.9 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.5 1.4 GO:0021569 rhombomere 3 development(GO:0021569)
0.4 2.0 GO:0070980 biphenyl catabolic process(GO:0070980)
0.4 2.4 GO:0003350 pulmonary myocardium development(GO:0003350)
0.3 3.3 GO:0009414 response to water deprivation(GO:0009414)
0.3 0.8 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.2 3.7 GO:0043589 skin morphogenesis(GO:0043589)
0.2 1.1 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.2 1.3 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.2 0.6 GO:0032771 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.2 1.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2 0.9 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2 0.7 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 1.8 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.2 0.9 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.7 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.1 0.8 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 1.4 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.1 0.3 GO:0031627 telomeric loop formation(GO:0031627) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.1 0.5 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 1.7 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 0.3 GO:1900229 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.1 2.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.3 GO:0031337 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.1 0.3 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971) fasciculation of sensory neuron axon(GO:0097155)
0.1 0.2 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.2 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.2 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1 0.6 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.8 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.4 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 2.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.2 GO:0033076 isoquinoline alkaloid metabolic process(GO:0033076)
0.1 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.3 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.5 GO:0015846 polyamine transport(GO:0015846)
0.0 0.2 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.2 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.4 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.3 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 2.7 GO:0035904 aorta development(GO:0035904)
0.0 0.6 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 1.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:0033133 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 2.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 2.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 4.1 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:1904616 regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
0.0 0.5 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.3 GO:0007512 adult heart development(GO:0007512)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 1.2 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.7 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 2.2 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 1.4 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.1 GO:1903960 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960)
0.0 0.3 GO:0030220 platelet formation(GO:0030220)
0.0 0.2 GO:0048485 sympathetic nervous system development(GO:0048485)
0.0 0.2 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.2 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 1.1 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 1.0 GO:0050918 positive chemotaxis(GO:0050918)
0.0 0.4 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.8 GO:0055007 cardiac muscle cell differentiation(GO:0055007)
0.0 0.6 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0007320 insemination(GO:0007320)
0.0 0.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.9 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 1.6 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.1 GO:0019321 pentose metabolic process(GO:0019321)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.6 1.7 GO:0051300 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.5 1.6 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.4 1.3 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.4 1.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.3 1.5 GO:0070842 aggresome assembly(GO:0070842)
0.3 1.7 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.3 0.8 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.3 0.8 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.2 1.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.2 0.9 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 1.0 GO:0044336 embryonic genitalia morphogenesis(GO:0030538) canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.2 0.8 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.2 0.6 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.2 0.6 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.2 0.9 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.2 1.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 0.9 GO:1904693 midbrain morphogenesis(GO:1904693)
0.2 0.5 GO:1902356 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.2 0.6 GO:0071895 odontoblast differentiation(GO:0071895)
0.2 1.7 GO:0006600 creatine metabolic process(GO:0006600)
0.2 0.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 1.0 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.6 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 0.7 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.1 1.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 2.6 GO:0006825 copper ion transport(GO:0006825)
0.1 0.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.5 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.2 GO:1905064 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.1 4.5 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.3 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.7 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.7 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.2 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.3 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.7 GO:0000165 MAPK cascade(GO:0000165)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.7 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.6 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.7 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.6 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0060339 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.3 GO:0051005 endosome transport via multivesicular body sorting pathway(GO:0032509) negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 1.4 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.2 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0072560 glandular epithelial cell maturation(GO:0002071) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) type B pancreatic cell maturation(GO:0072560)
0.0 0.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.0 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.1 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.5 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 0.5 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.3 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.7 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.4 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.8 GO:0070268 cornification(GO:0070268)
0.0 0.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.3 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 0.2 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.7 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.7 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.3 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.4 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0005607 laminin-2 complex(GO:0005607)
0.3 4.8 GO:0030478 actin cap(GO:0030478)
0.3 3.7 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 1.6 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 1.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 2.7 GO:0032433 filopodium tip(GO:0032433)
0.1 3.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.7 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.4 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 2.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.9 GO:0005610 laminin-5 complex(GO:0005610)
0.1 2.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 3.3 GO:0005605 basal lamina(GO:0005605)
0.1 0.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.2 GO:0031523 Myb complex(GO:0031523)
0.1 0.2 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 1.9 GO:0005685 U1 snRNP(GO:0005685)
0.1 4.1 GO:0005604 basement membrane(GO:0005604)
0.1 1.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.5 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 1.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 4.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 16.1 GO:0005925 focal adhesion(GO:0005925)
0.0 2.0 GO:0005811 lipid particle(GO:0005811)
0.0 2.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 3.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.0 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
1.2 4.7 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
1.1 10.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.5 1.5 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.4 4.8 GO:0039706 co-receptor binding(GO:0039706)
0.3 1.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 5.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 1.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.2 4.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 6.5 GO:0070064 proline-rich region binding(GO:0070064)
0.2 3.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 0.9 GO:0030492 hemoglobin binding(GO:0030492)
0.1 1.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.6 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 3.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 6.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.8 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.8 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.3 GO:0004803 transposase activity(GO:0004803)
0.1 7.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 5.3 GO:0005518 collagen binding(GO:0005518)
0.1 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 5.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 4.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 8.4 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 2.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.2 GO:0039706 co-receptor binding(GO:0039706)
0.3 3.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.3 3.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 1.8 GO:1990254 keratin filament binding(GO:1990254)
0.3 1.9 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.2 3.3 GO:0045499 chemorepellent activity(GO:0045499)
0.2 2.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 0.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 2.5 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 1.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 3.8 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.6 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.5 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 1.0 GO:0045545 syndecan binding(GO:0045545)
0.1 1.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 2.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.1 GO:0045159 myosin II binding(GO:0045159)
0.1 0.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 1.0 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 6.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.7 GO:0008430 selenium binding(GO:0008430)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 2.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.2 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 3.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.3 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.4 GO:0043426 MRF binding(GO:0043426)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 1.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.8 GO:0070410 co-SMAD binding(GO:0070410)
0.0 2.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 2.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 1.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0017057 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 4.6 GO:0003924 GTPase activity(GO:0003924)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.2 GO:0070330 aromatase activity(GO:0070330)
0.0 1.4 GO:0005178 integrin binding(GO:0005178)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.5 10.2 GO:0032433 filopodium tip(GO:0032433)
0.4 1.4 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.2 1.0 GO:0045179 apical cortex(GO:0045179)
0.2 0.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 2.8 GO:0043203 axon hillock(GO:0043203)
0.2 4.2 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 4.5 GO:0005605 basal lamina(GO:0005605)
0.1 1.0 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 13.4 GO:0005923 bicellular tight junction(GO:0005923)
0.1 2.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 4.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.0 10.5 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.7 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 4.9 GO:0043204 perikaryon(GO:0043204)
0.0 10.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 2.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 3.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 3.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.3 6.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 4.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 10.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 0.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 5.6 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 4.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 5.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 3.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.3 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.2 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.5 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 4.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 4.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 4.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.1 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.9 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.0 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.0 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 2.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 5.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.9 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 5.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.8 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 2.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.5 1.6 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.3 0.9 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.3 2.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 1.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 0.9 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.2 1.7 GO:0004111 creatine kinase activity(GO:0004111)
0.2 0.6 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.2 0.6 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2 0.9 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 0.5 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.2 0.6 GO:0038025 reelin receptor activity(GO:0038025)
0.1 0.4 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 2.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 3.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.7 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.4 GO:0004461 lactose synthase activity(GO:0004461)
0.1 1.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 1.5 GO:0070628 proteasome binding(GO:0070628)
0.1 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.3 GO:0002046 opsin binding(GO:0002046)
0.1 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 5.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.4 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.8 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.6 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976) primary miRNA binding(GO:0070878)
0.0 0.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 2.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.5 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 2.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)