Project

ENCODE cell lines, expression (Ernst 2011)

Navigation
Downloads

Results for TCF7L2

Z-value: 1.45

Motif logo

logo of

Transcription factors associated with TCF7L2

Gene Symbol Gene ID Gene Info
TCF7L2
ENSG00000148737.11 TCF7L2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7L2hg19_v2_chr10_+_114709999_1147100310.871.2e-05Click!

Activity profile of TCF7L2 motif

Sorted Z-values of TCF7L2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7L2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr5_-_16936340 7.93 ENST00000507288.1
ENST00000513610.1
 MYO10
 myosin X
chr11_+_69455855 6.54 ENST00000227507.2
ENST00000536559.1
 CCND1
 cyclin D1
chr11_+_114128522 5.98 ENST00000535401.1
 NNMT
 nicotinamide N-methyltransferase
chr13_+_76334795 5.46 ENST00000526202.1
ENST00000465261.2
 LMO7
 LIM domain 7
chr13_+_76334567 5.34 ENST00000321797.8
 LMO7
 LIM domain 7
chr10_+_54074033 4.76 ENST00000373970.3
 DKK1
 dickkopf WNT signaling pathway inhibitor 1
chr4_-_157892498 4.58 ENST00000502773.1
 PDGFC
 platelet derived growth factor C
chr3_-_134093275 4.20 ENST00000513145.1
ENST00000422605.2
 AMOTL2
 angiomotin like 2
chr3_-_134093395 3.85 ENST00000249883.5
 AMOTL2
 angiomotin like 2
chr1_-_153522562 3.81 ENST00000368714.1
 S100A4
 S100 calcium binding protein A4
chr13_+_102142296 3.75 ENST00000376162.3
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr8_-_119964434 3.49 ENST00000297350.4
 TNFRSF11B
 tumor necrosis factor receptor superfamily, member 11b
chr1_-_110933663 3.09 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
 SLC16A4
 solute carrier family 16, member 4
chrX_-_10588459 2.99 ENST00000380782.2
 MID1
 midline 1 (Opitz/BBB syndrome)
chr1_-_110933611 2.97 ENST00000472422.2
ENST00000437429.2
 SLC16A4
 solute carrier family 16, member 4
chr5_+_102201509 2.82 ENST00000348126.2
ENST00000379787.4
 PAM
 peptidylglycine alpha-amidating monooxygenase
chrX_-_10588595 2.81 ENST00000423614.1
ENST00000317552.4
 MID1
 midline 1 (Opitz/BBB syndrome)
chr17_+_1674982 2.81 ENST00000572048.1
ENST00000573763.1
 SERPINF1
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr5_-_16742330 2.29 ENST00000505695.1
ENST00000427430.2
 MYO10
 myosin X
chr10_+_7745232 2.26 ENST00000358415.4
 ITIH2
 inter-alpha-trypsin inhibitor heavy chain 2
chrX_+_54835493 2.22 ENST00000396224.1
 MAGED2
 melanoma antigen family D, 2
chr10_+_114709999 2.14 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
 TCF7L2
 transcription factor 7-like 2 (T-cell specific, HMG-box)
chr3_-_149375783 1.99 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
 WWTR1
 WW domain containing transcription regulator 1
chr10_+_7745303 1.93 ENST00000429820.1
ENST00000379587.4
 ITIH2
 inter-alpha-trypsin inhibitor heavy chain 2
chr5_+_102201430 1.91 ENST00000438793.3
ENST00000346918.2
 PAM
 peptidylglycine alpha-amidating monooxygenase
chr10_+_114710211 1.83 ENST00000349937.2
ENST00000369397.4
 TCF7L2
 transcription factor 7-like 2 (T-cell specific, HMG-box)
chr2_+_69240415 1.81 ENST00000409829.3
 ANTXR1
 anthrax toxin receptor 1
chr2_+_69240302 1.75 ENST00000303714.4
 ANTXR1
 anthrax toxin receptor 1
chr2_+_69240511 1.71 ENST00000409349.3
 ANTXR1
 anthrax toxin receptor 1
chr5_-_111093167 1.60 ENST00000446294.2
ENST00000419114.2
 NREP
 neuronal regeneration related protein
chr1_-_94079648 1.59 ENST00000370247.3
 BCAR3
 breast cancer anti-estrogen resistance 3
chr7_-_27213893 1.59 ENST00000283921.4
 HOXA10
 homeobox A10
chr6_-_112575687 1.56 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
 LAMA4
 laminin, alpha 4
chr2_+_228678550 1.51 ENST00000409189.3
ENST00000358813.4
 CCL20
 chemokine (C-C motif) ligand 20
chr6_-_112575912 1.49 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
 LAMA4
 laminin, alpha 4
chr10_+_114710425 1.46 ENST00000352065.5
ENST00000369395.1
 TCF7L2
 transcription factor 7-like 2 (T-cell specific, HMG-box)
chr12_+_1738363 1.40 ENST00000397196.2
 WNT5B
 wingless-type MMTV integration site family, member 5B
chr1_-_109935819 1.20 ENST00000538502.1
 SORT1
 sortilin 1
chr5_+_131593364 1.20 ENST00000253754.3
ENST00000379018.3
 PDLIM4
 PDZ and LIM domain 4
chr10_+_114710516 1.19 ENST00000542695.1
ENST00000346198.4
 TCF7L2
 transcription factor 7-like 2 (T-cell specific, HMG-box)
chr5_+_140797296 1.18 ENST00000398594.2
 PCDHGB7
 protocadherin gamma subfamily B, 7
chr5_+_140734570 1.08 ENST00000571252.1
 PCDHGA4
 protocadherin gamma subfamily A, 4
chr6_-_32145861 1.02 ENST00000336984.6
 AGPAT1
 1-acylglycerol-3-phosphate O-acyltransferase 1
chr5_-_148930960 0.97 ENST00000261798.5
ENST00000377843.2
 CSNK1A1
 casein kinase 1, alpha 1
chr2_-_88427568 0.97 ENST00000393750.3
ENST00000295834.3
 FABP1
 fatty acid binding protein 1, liver
chr16_+_72088376 0.94 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
 HP
HPR
 haptoglobin
haptoglobin-related protein
chr1_-_161993616 0.87 ENST00000294794.3
 OLFML2B
 olfactomedin-like 2B
chr4_+_78078304 0.87 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
 CCNG2
 cyclin G2
chr6_-_112575838 0.86 ENST00000455073.1
 LAMA4
 laminin, alpha 4
chr12_+_9067123 0.83 ENST00000543824.1
 PHC1
 polyhomeotic homolog 1 (Drosophila)
chr18_+_46065393 0.79 ENST00000256413.3
 CTIF
 CBP80/20-dependent translation initiation factor
chr8_+_32579341 0.77 ENST00000519240.1
ENST00000539990.1
 NRG1
 neuregulin 1
chr10_+_101542462 0.76 ENST00000370449.4
ENST00000370434.1
 ABCC2
 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chrX_+_46937745 0.76 ENST00000397180.1
ENST00000457380.1
ENST00000352078.4
 RGN
 regucalcin
chr14_-_61124977 0.74 ENST00000554986.1
 SIX1
 SIX homeobox 1
chr17_-_38256973 0.74 ENST00000246672.3
 NR1D1
 nuclear receptor subfamily 1, group D, member 1
chr13_-_36429763 0.73 ENST00000379893.1
 DCLK1
 doublecortin-like kinase 1
chr7_+_80275621 0.70 ENST00000426978.1
ENST00000432207.1
 CD36
 CD36 molecule (thrombospondin receptor)
chr10_+_71561630 0.70 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
 COL13A1
 collagen, type XIII, alpha 1
chr17_-_7297519 0.69 ENST00000576362.1
ENST00000571078.1
 TMEM256-PLSCR3
 TMEM256-PLSCR3 readthrough (NMD candidate)
chr7_+_80275752 0.67 ENST00000419819.2
 CD36
 CD36 molecule (thrombospondin receptor)
chr9_-_23826298 0.64 ENST00000380117.1
 ELAVL2
 ELAV like neuron-specific RNA binding protein 2
chr17_-_39093672 0.62 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
 KRT23
 keratin 23 (histone deacetylase inducible)
chr6_-_112575758 0.61 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
 LAMA4
 laminin, alpha 4
chr4_-_139163491 0.60 ENST00000280612.5
 SLC7A11
 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr17_-_56065484 0.58 ENST00000581208.1
 VEZF1
 vascular endothelial zinc finger 1
chr5_-_58335281 0.57 ENST00000358923.6
 PDE4D
 phosphodiesterase 4D, cAMP-specific
chr10_+_71561649 0.56 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
 COL13A1
 collagen, type XIII, alpha 1
chr17_-_7297833 0.55 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
 TMEM256-PLSCR3
 TMEM256-PLSCR3 readthrough (NMD candidate)
chr7_-_27219849 0.54 ENST00000396344.4
 HOXA10
 homeobox A10
chr7_+_99613212 0.52 ENST00000426572.1
ENST00000535170.1
 ZKSCAN1
 zinc finger with KRAB and SCAN domains 1
chrX_+_152760397 0.50 ENST00000331595.4
ENST00000431891.1
 BGN
 biglycan
chr18_+_46065483 0.50 ENST00000382998.4
 CTIF
 CBP80/20-dependent translation initiation factor
chr7_+_99613195 0.46 ENST00000324306.6
 ZKSCAN1
 zinc finger with KRAB and SCAN domains 1
chr7_+_80275953 0.45 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
 CD36
 CD36 molecule (thrombospondin receptor)
chr19_-_40791302 0.44 ENST00000392038.2
ENST00000578123.1
 AKT2
 v-akt murine thymoma viral oncogene homolog 2
chr7_-_148725733 0.43 ENST00000286091.4
 PDIA4
 protein disulfide isomerase family A, member 4
chr14_-_65409502 0.43 ENST00000389614.5
 GPX2
 glutathione peroxidase 2 (gastrointestinal)
chr4_+_30721968 0.41 ENST00000361762.2
 PCDH7
 protocadherin 7
chr5_+_66124590 0.41 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
 MAST4
 microtubule associated serine/threonine kinase family member 4
chr14_-_75179774 0.39 ENST00000555249.1
ENST00000556202.1
ENST00000356357.4
ENST00000338772.5
 AREL1
AC007956.1
 apoptosis resistant E3 ubiquitin protein ligase 1
Full-length cDNA 5-PRIME end of clone CS0CAP004YO05 of Thymus of Homo sapiens (human); Uncharacterized protein
chr13_-_67802549 0.39 ENST00000328454.5
ENST00000377865.2
 PCDH9
 protocadherin 9
chr6_-_25930819 0.37 ENST00000360488.3
 SLC17A2
 solute carrier family 17, member 2
chr12_+_122326630 0.34 ENST00000541212.1
ENST00000340175.5
 PSMD9
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr17_+_59529743 0.34 ENST00000589003.1
ENST00000393853.4
 TBX4
 T-box 4
chr7_+_73868439 0.34 ENST00000424337.2
 GTF2IRD1
 GTF2I repeat domain containing 1
chr13_-_72440901 0.33 ENST00000359684.2
 DACH1
 dachshund homolog 1 (Drosophila)
chr12_-_49582978 0.32 ENST00000301071.7
 TUBA1A
 tubulin, alpha 1a
chr12_+_122326662 0.32 ENST00000261817.2
ENST00000538613.1
ENST00000542602.1
 PSMD9
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr16_-_73082274 0.31 ENST00000268489.5
 ZFHX3
 zinc finger homeobox 3
chr19_-_40791211 0.31 ENST00000579047.1
 AKT2
 v-akt murine thymoma viral oncogene homolog 2
chrX_+_47004599 0.31 ENST00000329236.7
 RBM10
 RNA binding motif protein 10
chr2_-_55646957 0.31 ENST00000263630.8
 CCDC88A
 coiled-coil domain containing 88A
chr9_-_27005686 0.29 ENST00000380055.5
 LRRC19
 leucine rich repeat containing 19
chr6_-_25930904 0.29 ENST00000377850.3
 SLC17A2
 solute carrier family 17, member 2
chr14_+_21236586 0.29 ENST00000326783.3
 EDDM3B
 epididymal protein 3B
chr14_+_74815116 0.27 ENST00000256362.4
 VRTN
 vertebrae development associated
chr11_-_76155618 0.25 ENST00000530759.1
 RP11-111M22.3
 RP11-111M22.3
chrX_-_43832711 0.24 ENST00000378062.5
 NDP
 Norrie disease (pseudoglioma)
chr5_+_170846640 0.22 ENST00000274625.5
 FGF18
 fibroblast growth factor 18
chr2_-_55647057 0.21 ENST00000436346.1
 CCDC88A
 coiled-coil domain containing 88A
chr5_-_157002775 0.21 ENST00000257527.4
 ADAM19
 ADAM metallopeptidase domain 19
chr15_+_57511609 0.21 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
 TCF12
 transcription factor 12
chr11_-_76155700 0.19 ENST00000572035.1
 RP11-111M22.3
 RP11-111M22.3
chr7_+_110731062 0.19 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
 LRRN3
 leucine rich repeat neuronal 3
chr11_+_65408273 0.18 ENST00000394227.3
 SIPA1
 signal-induced proliferation-associated 1
chr2_+_71357434 0.18 ENST00000244230.2
 MPHOSPH10
 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr12_+_52056548 0.17 ENST00000545061.1
ENST00000355133.3
 SCN8A
 sodium channel, voltage gated, type VIII, alpha subunit
chr22_+_19950060 0.16 ENST00000449653.1
 COMT
 catechol-O-methyltransferase
chr6_-_11779403 0.16 ENST00000414691.3
 ADTRP
 androgen-dependent TFPI-regulating protein
chr10_+_71561704 0.15 ENST00000520267.1
 COL13A1
 collagen, type XIII, alpha 1
chr12_+_70760056 0.14 ENST00000258111.4
 KCNMB4
 potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr3_+_155838337 0.14 ENST00000490337.1
ENST00000389636.5
 KCNAB1
 potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr14_-_53258180 0.10 ENST00000554230.1
 GNPNAT1
 glucosamine-phosphate N-acetyltransferase 1
chr1_+_16330723 0.09 ENST00000329454.2
 C1orf64
 chromosome 1 open reading frame 64
chrX_-_122866874 0.09 ENST00000245838.8
ENST00000355725.4
 THOC2
 THO complex 2
chrX_+_47004639 0.08 ENST00000345781.6
 RBM10
 RNA binding motif protein 10
chr17_+_42923686 0.07 ENST00000591513.1
 HIGD1B
 HIG1 hypoxia inducible domain family, member 1B
chr7_-_75452673 0.07 ENST00000416943.1
 CCL24
 chemokine (C-C motif) ligand 24
chr2_+_71357744 0.07 ENST00000498451.2
 MPHOSPH10
 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr12_-_23737534 0.07 ENST00000396007.2
 SOX5
 SRY (sex determining region Y)-box 5
chr6_+_64281906 0.06 ENST00000370651.3
 PTP4A1
 protein tyrosine phosphatase type IVA, member 1
chr5_+_175288631 0.06 ENST00000509837.1
 CPLX2
 complexin 2
chr4_-_69215467 0.05 ENST00000579690.1
 YTHDC1
 YTH domain containing 1
chr22_+_41347363 0.05 ENST00000216225.8
 RBX1
 ring-box 1, E3 ubiquitin protein ligase
chr2_+_204732666 0.04 ENST00000295854.6
ENST00000472206.1
 CTLA4
 cytotoxic T-lymphocyte-associated protein 4
chr5_-_157002749 0.04 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
 ADAM19
 ADAM metallopeptidase domain 19
chr5_-_135290705 0.04 ENST00000274507.1
 LECT2
 leukocyte cell-derived chemotaxin 2
chr18_-_52989217 0.03 ENST00000570287.2
 TCF4
 transcription factor 4
chr20_-_17511962 0.02 ENST00000377873.3
 BFSP1
 beaded filament structural protein 1, filensin
chr4_-_109684120 0.01 ENST00000512646.1
ENST00000411864.2
ENST00000296486.3
ENST00000510706.1
 ETNPPL
 ethanolamine-phosphate phospho-lyase
chr3_+_183353356 0.00 ENST00000242810.6
ENST00000493074.1
ENST00000437402.1
ENST00000454495.2
ENST00000473045.1
ENST00000468101.1
ENST00000427201.2
ENST00000482138.1
ENST00000454652.2
 KLHL24
 kelch-like family member 24

Gene Ontology Analysis

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 5.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 10.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 4.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 4.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 2.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 5.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 11.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 5.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
1.6 4.8 GO:0009996 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996) Wnt signaling pathway involved in somitogenesis(GO:0090244)
1.2 4.7 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
1.1 6.6 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.7 6.5 GO:0070141 response to UV-A(GO:0070141)
0.6 2.3 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.6 2.8 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.5 1.5 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.5 6.0 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.4 5.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.4 0.8 GO:1904833 positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.3 2.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.3 0.9 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.3 1.8 GO:2000334 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.3 0.8 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787) response to antineoplastic agent(GO:0097327)
0.2 0.7 GO:0061055 myotome development(GO:0061055) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2 0.7 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.2 5.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.2 10.0 GO:0035329 hippo signaling(GO:0035329)
0.2 0.7 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 10.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 1.0 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.7 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 1.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 1.0 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 1.4 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 2.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 1.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 1.0 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 3.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072) positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.2 GO:0016036 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 5.8 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.4 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.8 GO:0016574 histone ubiquitination(GO:0016574)
0.0 10.0 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 3.0 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 3.8 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.3 GO:0032196 transposition(GO:0032196)
0.0 1.3 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.6 GO:0001885 endothelial cell development(GO:0001885)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.0 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
1.2 4.7 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
1.1 10.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.5 1.5 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.4 4.8 GO:0039706 co-receptor binding(GO:0039706)
0.3 1.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 5.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 1.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.2 4.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 6.5 GO:0070064 proline-rich region binding(GO:0070064)
0.2 3.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 0.9 GO:0030492 hemoglobin binding(GO:0030492)
0.1 1.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.6 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 3.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 6.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.8 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.8 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.3 GO:0004803 transposase activity(GO:0004803)
0.1 7.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 5.3 GO:0005518 collagen binding(GO:0005518)
0.1 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 5.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 4.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 8.4 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 2.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.5 10.2 GO:0032433 filopodium tip(GO:0032433)
0.4 1.4 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.2 1.0 GO:0045179 apical cortex(GO:0045179)
0.2 0.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 2.8 GO:0043203 axon hillock(GO:0043203)
0.2 4.2 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 4.5 GO:0005605 basal lamina(GO:0005605)
0.1 1.0 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 13.4 GO:0005923 bicellular tight junction(GO:0005923)
0.1 2.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 4.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.0 10.5 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.7 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 4.9 GO:0043204 perikaryon(GO:0043204)
0.0 10.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 2.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 3.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 3.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.3 6.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 4.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 10.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 0.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 5.6 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events