ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
TEAD4 Links Ensembl NCBI GeneCards UniProt	ENSG00000197905.4	TEAD4

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TEAD4	hg19_v2_chr12_+_3068466_3068496, hg19_v2_chr12_+_3069037_3069119, hg19_v2_chr12_+_3068544_3068597	0.67	4.2e-03	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr4_-_110723134	4.45	ENST00000510800.1 ENST00000512148.1	CFI	complement factor I
chr4_-_110723335	3.94	ENST00000394634.2	CFI	complement factor I
chr2_+_228678550	3.73	ENST00000409189.3 ENST00000358813.4	CCL20	chemokine (C-C motif) ligand 20
chr4_-_110723194	3.49	ENST00000394635.3	CFI	complement factor I
chr2_-_188419200	2.80	ENST00000233156.3 ENST00000426055.1 ENST00000453013.1 ENST00000417013.1	TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr2_-_188419078	2.79	ENST00000437725.1 ENST00000409676.1 ENST00000339091.4 ENST00000420747.1	TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr13_-_46679144	2.15	ENST00000181383.4	CPB2	carboxypeptidase B2 (plasma)
chr13_-_46679185	2.15	ENST00000439329.3	CPB2	carboxypeptidase B2 (plasma)
chr5_-_111093167	2.11	ENST00000446294.2 ENST00000419114.2	NREP	neuronal regeneration related protein
chr13_+_113760098	2.04	ENST00000346342.3 ENST00000541084.1 ENST00000375581.3	F7	coagulation factor VII (serum prothrombin conversion accelerator)
chr4_-_155533787	1.76	ENST00000407946.1 ENST00000405164.1 ENST00000336098.3 ENST00000393846.2 ENST00000404648.3 ENST00000443553.1	FGG	fibrinogen gamma chain
chr12_-_91539918	1.71	ENST00000548218.1	DCN	decorin
chr20_+_43160458	1.55	ENST00000372889.1 ENST00000372887.1 ENST00000372882.3	PKIG	protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr1_+_169079823	1.50	ENST00000367813.3	ATP1B1	ATPase, Na+/K+ transporting, beta 1 polypeptide
chr4_-_155511887	1.49	ENST00000302053.3 ENST00000403106.3	FGA	fibrinogen alpha chain
chr3_-_52486841	1.49	ENST00000496590.1	TNNC1	troponin C type 1 (slow)
chr10_-_90712520	1.44	ENST00000224784.6	ACTA2	actin, alpha 2, smooth muscle, aorta
chr4_-_186732048	1.43	ENST00000448662.2 ENST00000439049.1 ENST00000420158.1 ENST00000431808.1 ENST00000319471.9	SORBS2	sorbin and SH3 domain containing 2
chr17_+_4855053	1.40	ENST00000518175.1	ENO3	enolase 3 (beta, muscle)
chr10_-_75410771	1.39	ENST00000372873.4	SYNPO2L	synaptopodin 2-like
chr18_-_25616519	1.31	ENST00000399380.3	CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr14_-_89883412	1.30	ENST00000557258.1	FOXN3	forkhead box N3
chr16_+_30386098	1.22	ENST00000322861.7	MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle
chr15_+_80733570	1.21	ENST00000533983.1 ENST00000527771.1 ENST00000525103.1	ARNT2	aryl-hydrocarbon receptor nuclear translocator 2
chr12_-_91572278	1.19	ENST00000425043.1 ENST00000420120.2 ENST00000441303.2 ENST00000456569.2	DCN	decorin
chr19_+_35630022	1.19	ENST00000589209.1	FXYD1	FXYD domain containing ion transport regulator 1
chr19_+_35630628	1.15	ENST00000588715.1 ENST00000588607.1	FXYD1	FXYD domain containing ion transport regulator 1
chr16_-_73093597	1.07	ENST00000397992.5	ZFHX3	zinc finger homeobox 3
chr2_-_211168332	1.06	ENST00000341685.4	MYL1	myosin, light chain 1, alkali; skeletal, fast
chr11_-_63376013	0.99	ENST00000540943.1	PLA2G16	phospholipase A2, group XVI
chr2_-_99279928	0.99	ENST00000414521.2	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr7_-_22234381	0.99	ENST00000458533.1	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5
chr9_+_90112117	0.99	ENST00000358077.5	DAPK1	death-associated protein kinase 1
chr10_+_5005445	0.98	ENST00000380872.4	AKR1C1	aldo-keto reductase family 1, member C1
chr5_+_53751445	0.98	ENST00000302005.1	HSPB3	heat shock 27kDa protein 3
chr10_-_735553	0.94	ENST00000280886.6 ENST00000423550.1	DIP2C	DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr2_+_152214098	0.90	ENST00000243347.3	TNFAIP6	tumor necrosis factor, alpha-induced protein 6
chr2_+_108905325	0.88	ENST00000438339.1 ENST00000409880.1 ENST00000437390.2	SULT1C2	sulfotransferase family, cytosolic, 1C, member 2
chr2_+_38893047	0.84	ENST00000272252.5	GALM	galactose mutarotase (aldose 1-epimerase)
chr2_-_179672142	0.83	ENST00000342992.6 ENST00000360870.5 ENST00000460472.2 ENST00000589042.1 ENST00000591111.1 ENST00000342175.6 ENST00000359218.5	TTN	titin
chr2_+_238768187	0.79	ENST00000254661.4 ENST00000409726.1	RAMP1	receptor (G protein-coupled) activity modifying protein 1
chr3_+_123813543	0.79	ENST00000360013.3	KALRN	kalirin, RhoGEF kinase
chr2_+_238767517	0.77	ENST00000404910.2	RAMP1	receptor (G protein-coupled) activity modifying protein 1
chr6_-_152489484	0.76	ENST00000354674.4 ENST00000539504.1	SYNE1	spectrin repeat containing, nuclear envelope 1
chr11_+_12766583	0.76	ENST00000361985.2	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr12_+_109554386	0.75	ENST00000338432.7	ACACB	acetyl-CoA carboxylase beta
chr18_+_55862622	0.70	ENST00000456173.2	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr6_-_52705641	0.69	ENST00000370989.2	GSTA5	glutathione S-transferase alpha 5
chr11_+_120255997	0.68	ENST00000532993.1	ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12
chr4_-_89978299	0.65	ENST00000511976.1 ENST00000509094.1 ENST00000264344.5 ENST00000515600.1	FAM13A	family with sequence similarity 13, member A
chrX_+_49832231	0.64	ENST00000376108.3	CLCN5	chloride channel, voltage-sensitive 5
chr12_-_123011476	0.64	ENST00000528279.1 ENST00000344591.4 ENST00000526560.2	RSRC2	arginine/serine-rich coiled-coil 2
chr6_-_109330702	0.62	ENST00000356644.7	SESN1	sestrin 1
chr6_-_152958521	0.61	ENST00000367255.5 ENST00000265368.4 ENST00000448038.1 ENST00000341594.5	SYNE1	spectrin repeat containing, nuclear envelope 1
chr1_-_227505289	0.60	ENST00000366765.3	CDC42BPA	CDC42 binding protein kinase alpha (DMPK-like)
chr1_-_79472365	0.58	ENST00000370742.3	ELTD1	EGF, latrophilin and seven transmembrane domain containing 1
chr2_+_223916862	0.57	ENST00000604125.1	KCNE4	potassium voltage-gated channel, Isk-related family, member 4
chrX_-_77150985	0.54	ENST00000358075.6	MAGT1	magnesium transporter 1
chr3_+_138067666	0.53	ENST00000475711.1 ENST00000464896.1	MRAS	muscle RAS oncogene homolog
chr2_-_231989808	0.52	ENST00000258400.3	HTR2B	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr17_-_38545799	0.51	ENST00000577541.1	TOP2A	topoisomerase (DNA) II alpha 170kDa
chr10_+_123923205	0.51	ENST00000369004.3 ENST00000260733.3	TACC2	transforming, acidic coiled-coil containing protein 2
chr1_-_154928562	0.50	ENST00000368463.3 ENST00000539880.1 ENST00000542459.1 ENST00000368460.3 ENST00000368465.1	PBXIP1	pre-B-cell leukemia homeobox interacting protein 1
chr4_+_120056939	0.49	ENST00000307128.5	MYOZ2	myozenin 2
chr7_+_120629653	0.49	ENST00000450913.2 ENST00000340646.5	CPED1	cadherin-like and PC-esterase domain containing 1
chr11_+_17316870	0.48	ENST00000458064.2	NUCB2	nucleobindin 2
chr19_-_41256207	0.47	ENST00000598485.2 ENST00000470681.1 ENST00000339153.3 ENST00000598729.1	C19orf54	chromosome 19 open reading frame 54
chr22_+_24115000	0.46	ENST00000215743.3	MMP11	matrix metallopeptidase 11 (stromelysin 3)
chr4_+_41614909	0.45	ENST00000509454.1 ENST00000396595.3 ENST00000381753.4	LIMCH1	LIM and calponin homology domains 1
chr3_+_197518100	0.45	ENST00000438796.2 ENST00000414675.2 ENST00000441090.2 ENST00000334859.4 ENST00000425562.2	LRCH3	leucine-rich repeats and calponin homology (CH) domain containing 3
chrX_-_33146477	0.44	ENST00000378677.2	DMD	dystrophin
chr17_+_32582293	0.44	ENST00000580907.1 ENST00000225831.4	CCL2	chemokine (C-C motif) ligand 2
chr12_-_49333446	0.43	ENST00000537495.1	AC073610.5	Uncharacterized protein
chr3_-_11685345	0.42	ENST00000430365.2	VGLL4	vestigial like 4 (Drosophila)
chr1_+_163038565	0.39	ENST00000421743.2	RGS4	regulator of G-protein signaling 4
chr2_-_20251744	0.39	ENST00000175091.4	LAPTM4A	lysosomal protein transmembrane 4 alpha
chr6_+_153552455	0.38	ENST00000392385.2	AL590867.1	Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr22_+_38142235	0.35	ENST00000407319.2 ENST00000403663.2 ENST00000428075.1	TRIOBP	TRIO and F-actin binding protein
chr15_+_100106126	0.34	ENST00000558812.1 ENST00000338042.6	MEF2A	myocyte enhancer factor 2A
chr12_-_123011536	0.34	ENST00000331738.7 ENST00000354654.2	RSRC2	arginine/serine-rich coiled-coil 2
chr1_-_59249732	0.34	ENST00000371222.2	JUN	jun proto-oncogene
chr11_-_71639670	0.33	ENST00000533047.1 ENST00000529844.1	RP11-849H4.2	Putative short transient receptor potential channel 2-like protein
chr4_-_89152474	0.33	ENST00000515655.1	ABCG2	ATP-binding cassette, sub-family G (WHITE), member 2
chr19_-_19144243	0.32	ENST00000594445.1 ENST00000452918.2 ENST00000600377.1 ENST00000337018.6	SUGP2	SURP and G patch domain containing 2
chr13_-_38172863	0.32	ENST00000541481.1 ENST00000379743.4 ENST00000379742.4 ENST00000379749.4 ENST00000541179.1 ENST00000379747.4	POSTN	periostin, osteoblast specific factor
chr2_+_90060377	0.32	ENST00000436451.2	IGKV6D-21	immunoglobulin kappa variable 6D-21 (non-functional)
chr19_+_35630344	0.32	ENST00000455515.2	FXYD1	FXYD domain containing ion transport regulator 1
chr11_-_71639480	0.31	ENST00000529513.1	RP11-849H4.2	Putative short transient receptor potential channel 2-like protein
chr8_+_107282389	0.30	ENST00000577661.1 ENST00000445937.1	RP11-395G23.3 OXR1	RP11-395G23.3 oxidation resistance 1
chr10_-_50970322	0.30	ENST00000374103.4	OGDHL	oxoglutarate dehydrogenase-like
chr3_-_185538849	0.30	ENST00000421047.2	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr2_-_128568721	0.29	ENST00000322313.4 ENST00000393006.1 ENST00000409658.3 ENST00000436787.1	WDR33	WD repeat domain 33
chr15_+_100106155	0.29	ENST00000557785.1 ENST00000558049.1 ENST00000449277.2	MEF2A	myocyte enhancer factor 2A
chr1_+_206516200	0.29	ENST00000295713.5	SRGAP2	SLIT-ROBO Rho GTPase activating protein 2
chr20_+_47538357	0.29	ENST00000371917.4	ARFGEF2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr12_-_76478446	0.29	ENST00000393263.3 ENST00000548044.1 ENST00000547704.1 ENST00000431879.3 ENST00000549596.1 ENST00000550934.1 ENST00000551600.1 ENST00000547479.1 ENST00000547773.1 ENST00000544816.1 ENST00000542344.1 ENST00000548273.1	NAP1L1	nucleosome assembly protein 1-like 1
chr1_-_60392452	0.28	ENST00000371204.3	CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2
chr10_-_50970382	0.28	ENST00000419399.1 ENST00000432695.1	OGDHL	oxoglutarate dehydrogenase-like
chr12_-_111358372	0.28	ENST00000548438.1 ENST00000228841.8	MYL2	myosin, light chain 2, regulatory, cardiac, slow
chr15_+_100106244	0.27	ENST00000557942.1	MEF2A	myocyte enhancer factor 2A
chr2_-_89459813	0.26	ENST00000390256.2	IGKV6-21	immunoglobulin kappa variable 6-21 (non-functional)
chr4_+_55095264	0.26	ENST00000257290.5	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide
chr9_+_71944241	0.25	ENST00000257515.8	FAM189A2	family with sequence similarity 189, member A2
chr2_+_1418154	0.25	ENST00000423320.1 ENST00000382198.1	TPO	thyroid peroxidase
chr21_-_27423339	0.24	ENST00000415997.1	APP	amyloid beta (A4) precursor protein
chr21_+_47878757	0.23	ENST00000400274.1 ENST00000427143.2 ENST00000318711.7 ENST00000457905.3 ENST00000466639.1 ENST00000435722.3 ENST00000417564.2	DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)
chr6_-_25830785	0.23	ENST00000468082.1	SLC17A1	solute carrier family 17 (organic anion transporter), member 1
chr16_+_29991673	0.22	ENST00000416441.2	TAOK2	TAO kinase 2
chr5_-_138775177	0.20	ENST00000302060.5	DNAJC18	DnaJ (Hsp40) homolog, subfamily C, member 18
chr13_+_24553933	0.19	ENST00000424834.2 ENST00000439928.2	SPATA13 RP11-309I15.1	spermatogenesis associated 13 RP11-309I15.1
chr12_+_86268065	0.19	ENST00000551529.1 ENST00000256010.6	NTS	neurotensin
chr1_-_156252590	0.19	ENST00000361813.5 ENST00000368267.5	SMG5	SMG5 nonsense mediated mRNA decay factor
chr2_-_42588338	0.18	ENST00000234301.2	COX7A2L	cytochrome c oxidase subunit VIIa polypeptide 2 like
chr8_+_50824233	0.18	ENST00000522124.1	SNTG1	syntrophin, gamma 1
chr5_-_54281491	0.18	ENST00000381405.4	ESM1	endothelial cell-specific molecule 1
chr11_+_62009653	0.17	ENST00000244926.3	SCGB1D2	secretoglobin, family 1D, member 2
chr2_-_89513402	0.17	ENST00000498435.1	IGKV1-27	immunoglobulin kappa variable 1-27
chr5_-_10308125	0.17	ENST00000296658.3	CMBL	carboxymethylenebutenolidase homolog (Pseudomonas)
chr1_+_244214577	0.16	ENST00000358704.4	ZBTB18	zinc finger and BTB domain containing 18
chr11_-_6440624	0.15	ENST00000311051.3	APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr19_-_15443318	0.15	ENST00000360016.5	BRD4	bromodomain containing 4
chr17_+_44588877	0.14	ENST00000576629.1	LRRC37A2	leucine rich repeat containing 37, member A2
chr4_-_47983519	0.14	ENST00000358519.4 ENST00000544810.1 ENST00000402813.3	CNGA1	cyclic nucleotide gated channel alpha 1
chr4_+_41614720	0.14	ENST00000509277.1	LIMCH1	LIM and calponin homology domains 1
chr16_-_46655538	0.13	ENST00000303383.3	SHCBP1	SHC SH2-domain binding protein 1
chr10_+_32856764	0.13	ENST00000375030.2 ENST00000375028.3	C10orf68	Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr1_+_164528866	0.12	ENST00000420696.2	PBX1	pre-B-cell leukemia homeobox 1
chr11_-_10590118	0.11	ENST00000529598.1	LYVE1	lymphatic vessel endothelial hyaluronan receptor 1
chr10_+_93683519	0.11	ENST00000265990.6	BTAF1	BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
chr7_-_14029283	0.11	ENST00000433547.1 ENST00000405192.2	ETV1	ets variant 1
chr2_-_119605253	0.10	ENST00000295206.6	EN1	engrailed homeobox 1
chr4_-_186317034	0.10	ENST00000505916.1	LRP2BP	LRP2 binding protein
chr19_+_19144384	0.10	ENST00000392335.2 ENST00000535612.1 ENST00000537263.1 ENST00000540707.1 ENST00000541725.1 ENST00000269932.6 ENST00000546344.1 ENST00000540792.1 ENST00000536098.1 ENST00000541898.1 ENST00000543877.1	ARMC6	armadillo repeat containing 6
chr3_-_164875850	0.10	ENST00000472120.1	RP11-747D18.1	RP11-747D18.1
chr4_-_149365827	0.09	ENST00000344721.4	NR3C2	nuclear receptor subfamily 3, group C, member 2
chr12_-_58220078	0.09	ENST00000549039.1	CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr9_-_15472730	0.08	ENST00000481862.1	PSIP1	PC4 and SFRS1 interacting protein 1
chr22_-_50524298	0.08	ENST00000311597.5	MLC1	megalencephalic leukoencephalopathy with subcortical cysts 1
chr15_+_81475047	0.08	ENST00000559388.1	IL16	interleukin 16
chr7_-_116963334	0.08	ENST00000265441.3	WNT2	wingless-type MMTV integration site family member 2
chr17_-_66951474	0.08	ENST00000269080.2	ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8
chr11_+_55029628	0.07	ENST00000417545.2	TRIM48	tripartite motif containing 48
chrX_-_15402498	0.07	ENST00000297904.3	FIGF	c-fos induced growth factor (vascular endothelial growth factor D)
chr11_-_10590238	0.07	ENST00000256178.3	LYVE1	lymphatic vessel endothelial hyaluronan receptor 1
chr4_+_70861647	0.07	ENST00000246895.4 ENST00000381060.2	STATH	statherin
chr9_-_33402506	0.07	ENST00000377425.4 ENST00000537089.1 ENST00000297988.1 ENST00000539936.1 ENST00000541274.1	AQP7	aquaporin 7
chr1_+_46016703	0.06	ENST00000481885.1 ENST00000351829.4 ENST00000471651.1	AKR1A1	aldo-keto reductase family 1, member A1 (aldehyde reductase)
chr10_+_47894572	0.06	ENST00000355876.5	FAM21B	family with sequence similarity 21, member B
chr1_-_151798546	0.06	ENST00000356728.6	RORC	RAR-related orphan receptor C
chr9_-_104145795	0.05	ENST00000259407.2	BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr4_+_71588372	0.05	ENST00000536664.1	RUFY3	RUN and FYVE domain containing 3
chr12_+_32260085	0.05	ENST00000548411.1 ENST00000281474.5 ENST00000551086.1	BICD1	bicaudal D homolog 1 (Drosophila)
chr3_+_132316081	0.05	ENST00000249887.2	ACKR4	atypical chemokine receptor 4
chr19_+_10541462	0.04	ENST00000293683.5	PDE4A	phosphodiesterase 4A, cAMP-specific
chr14_-_106622419	0.04	ENST00000390604.2	IGHV3-16	immunoglobulin heavy variable 3-16 (non-functional)
chr1_+_66458072	0.04	ENST00000423207.2	PDE4B	phosphodiesterase 4B, cAMP-specific
chr7_+_80267973	0.04	ENST00000394788.3 ENST00000447544.2	CD36	CD36 molecule (thrombospondin receptor)
chr14_+_56127989	0.04	ENST00000555573.1	KTN1	kinectin 1 (kinesin receptor)
chr12_+_10460417	0.04	ENST00000381908.3 ENST00000336164.4 ENST00000350274.5	KLRD1	killer cell lectin-like receptor subfamily D, member 1
chr12_+_20963632	0.04	ENST00000540853.1 ENST00000261196.2	SLCO1B3	solute carrier organic anion transporter family, member 1B3
chr19_-_3786253	0.03	ENST00000585778.1	MATK	megakaryocyte-associated tyrosine kinase
chr4_+_40337340	0.03	ENST00000310169.2	CHRNA9	cholinergic receptor, nicotinic, alpha 9 (neuronal)
chr19_-_50083822	0.03	ENST00000596358.1	NOSIP	nitric oxide synthase interacting protein
chr4_-_39033963	0.03	ENST00000381938.3	TMEM156	transmembrane protein 156
chr5_+_118812294	0.02	ENST00000509514.1	HSD17B4	hydroxysteroid (17-beta) dehydrogenase 4
chr1_-_87379785	0.02	ENST00000401030.3 ENST00000370554.1	SEP15	Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr17_+_47865917	0.02	ENST00000259021.4 ENST00000454930.2 ENST00000509773.1 ENST00000510819.1 ENST00000424009.2	KAT7	K(lysine) acetyltransferase 7
chr19_-_50083803	0.02	ENST00000391853.3 ENST00000339093.3	NOSIP	nitric oxide synthase interacting protein
chr19_+_54369608	0.02	ENST00000336967.3	MYADM	myeloid-associated differentiation marker
chr7_+_77167343	0.01	ENST00000433369.2 ENST00000415482.2	PTPN12	protein tyrosine phosphatase, non-receptor type 12
chr5_+_138609782	0.01	ENST00000361059.2 ENST00000514694.1 ENST00000504203.1 ENST00000502929.1 ENST00000394800.2 ENST00000509644.1 ENST00000505016.1	MATR3	matrin 3
chr21_-_44299626	0.01	ENST00000330317.2 ENST00000398208.2	WDR4	WD repeat domain 4
chr13_+_49280951	0.01	ENST00000282018.3	CYSLTR2	cysteinyl leukotriene receptor 2
chr3_+_138327417	0.01	ENST00000338446.4	FAIM	Fas apoptotic inhibitory molecule
chrX_+_37639302	0.01	ENST00000545017.1 ENST00000536160.1	CYBB	cytochrome b-245, beta polypeptide
chr8_+_55370487	0.00	ENST00000297316.4	SOX17	SRY (sex determining region Y)-box 17
chr14_+_78870030	0.00	ENST00000553631.1 ENST00000554719.1	NRXN3	neurexin 3
chr22_+_35653445	0.00	ENST00000420166.1 ENST00000444518.2 ENST00000455359.1 ENST00000216106.5	HMGXB4	HMG box domain containing 4
chr20_+_60174827	0.00	ENST00000543233.1	CDH4	cadherin 4, type 1, R-cadherin (retinal)
chr5_+_174151536	0.00	ENST00000239243.6 ENST00000507785.1	MSX2	msh homeobox 2
chr4_-_100356844	0.00	ENST00000437033.2	ADH7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.5	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	3.3	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1	3.7	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	1.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.6	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.5	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.0	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	1.1	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.9	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.3	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.6	PID CDC42 PATHWAY	CDC42 signaling events

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.7	GO:0045362	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
1.1	4.3	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
1.0	7.6	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.5	4.1	GO:1903278	regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
0.4	1.5	GO:0032972	diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.3	0.8	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499)
0.3	0.8	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
0.3	1.3	GO:2000809	positive regulation of synaptic vesicle clustering(GO:2000809)
0.2	2.9	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2	1.4	GO:0090131	mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.2	0.8	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.2	0.7	GO:2001295	malonyl-CoA biosynthetic process(GO:2001295)
0.2	1.6	GO:0097647	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2	0.9	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.1	1.5	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	0.4	GO:1901624	negative regulation of lymphocyte chemotaxis(GO:1901624)
0.1	1.0	GO:0046485	ether lipid metabolic process(GO:0046485)
0.1	1.0	GO:0071395	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1	0.7	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1	1.4	GO:0090292	nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.6	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.1	0.3	GO:1990523	bone regeneration(GO:1990523)
0.1	0.5	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1	1.6	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	1.8	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.1	0.3	GO:0072277	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1	0.3	GO:0035026	leading edge cell differentiation(GO:0035026)
0.1	1.3	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.1	0.6	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.1	10.8	GO:0030449	regulation of complement activation(GO:0030449)
0.1	0.3	GO:0021815	modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.1	0.4	GO:0030047	actin modification(GO:0030047)
0.1	0.5	GO:0015693	magnesium ion transport(GO:0015693)
0.1	1.3	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.1	0.2	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1	0.5	GO:0030263	resolution of meiotic recombination intermediates(GO:0000712) apoptotic chromosome condensation(GO:0030263)
0.0	0.2	GO:0071874	cellular response to norepinephrine stimulus(GO:0071874)
0.0	1.4	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.4	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0	0.6	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.3	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.0	1.0	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.9	GO:0051923	sulfation(GO:0051923)
0.0	1.4	GO:0061621	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0	0.2	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0	0.1	GO:0061743	motor learning(GO:0061743)
0.0	0.8	GO:1902895	positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0	0.1	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853)
0.0	0.3	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.0	1.1	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	1.4	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.0	0.5	GO:0071711	basement membrane organization(GO:0071711)
0.0	0.1	GO:1904954	canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.0	0.6	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.4	GO:0030728	ovulation(GO:0030728)
0.0	0.1	GO:0015793	glycerol transport(GO:0015793)
0.0	0.6	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.0	0.1	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.1	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0	0.2	GO:0010629	negative regulation of gene expression(GO:0010629)
0.0	0.3	GO:0006590	thyroid hormone generation(GO:0006590)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	11.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.3	10.9	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	2.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.0	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	4.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.0	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	3.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	1.0	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	1.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.5	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	1.5	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	1.4	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.9	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.9	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	1.3	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.7	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	1.3	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.8	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.7	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	1.6	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.4	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.7	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.4	1.6	GO:0031716	calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.2	1.0	GO:0047023	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.2	1.4	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.2	1.0	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2	12.0	GO:0005044	scavenger receptor activity(GO:0005044)
0.2	0.7	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
0.2	0.5	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1	0.4	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.1	4.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	1.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	1.5	GO:0031013	troponin I binding(GO:0031013)
0.1	1.3	GO:0031433	telethonin binding(GO:0031433)
0.1	0.6	GO:0070728	leucine binding(GO:0070728)
0.1	0.6	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	1.3	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	1.5	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.7	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	1.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.3	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	1.6	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	1.0	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.8	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1	2.5	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	0.2	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.1	1.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.5	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	0.4	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	1.4	GO:0005521	lamin binding(GO:0005521)
0.0	4.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.5	GO:0051378	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0	0.3	GO:0004447	iodide peroxidase activity(GO:0004447)
0.0	2.9	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	1.1	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.9	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.8	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.0	0.4	GO:0045159	myosin II binding(GO:0045159)
0.0	0.8	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	2.6	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.6	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.2	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.1	GO:0042169	SH2 domain binding(GO:0042169)
0.0	1.0	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.3	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.1	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.5	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.7	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.3	GO:0070330	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) aromatase activity(GO:0070330)
0.0	1.1	GO:0008022	protein C-terminus binding(GO:0008022)
0.0	0.3	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.4	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.4	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.3	3.3	GO:0005577	fibrinogen complex(GO:0005577)
0.2	1.5	GO:1990584	cardiac Troponin complex(GO:1990584)
0.2	1.4	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.2	1.6	GO:1903440	calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2	4.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2	2.9	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	0.5	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.2	0.8	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.1	1.3	GO:0016342	catenin complex(GO:0016342)
0.1	1.4	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.3	GO:0005879	axonemal microtubule(GO:0005879)
0.1	0.6	GO:0061700	GATOR2 complex(GO:0061700)
0.1	0.6	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.1	2.7	GO:0005859	muscle myosin complex(GO:0005859)
0.1	0.6	GO:0016013	syntrophin complex(GO:0016013)
0.0	0.5	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.4	GO:1990761	growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0	0.3	GO:0035976	AP1 complex(GO:0035976)
0.0	5.2	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.3	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.3	GO:0097512	cardiac myofibril(GO:0097512)
0.0	0.3	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	2.4	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.0	GO:0033647	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0	0.1	GO:1990909	Wnt signalosome(GO:1990909)
0.0	1.0	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.1	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.6	GO:0005771	multivesicular body(GO:0005771)
0.0	17.1	GO:0005615	extracellular space(GO:0005615)
0.0	1.6	GO:0030018	Z disc(GO:0030018)