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ENCODE cell lines, expression (Ernst 2011)

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Results for TFAP2B

Z-value: 1.26

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Transcription factors associated with TFAP2B

Gene Symbol Gene ID Gene Info
TFAP2B
ENSG00000008196.8 TFAP2B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Bhg19_v2_chr6_+_50786414_507864390.283.0e-01Click!

Activity profile of TFAP2B motif

Sorted Z-values of TFAP2B motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2B

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr17_-_39677971 2.80 ENST00000393976.2
 KRT15
 keratin 15
chr12_-_89746173 2.27 ENST00000308385.6
 DUSP6
 dual specificity phosphatase 6
chr6_-_138428613 2.11 ENST00000421351.3
 PERP
 PERP, TP53 apoptosis effector
chr16_+_22825475 2.05 ENST00000261374.3
 HS3ST2
 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr15_+_101420028 2.03 ENST00000557963.1
ENST00000346623.6
 ALDH1A3
 aldehyde dehydrogenase 1 family, member A3
chr16_+_68678892 1.97 ENST00000429102.2
 CDH3
 cadherin 3, type 1, P-cadherin (placental)
chr1_-_153588334 1.81 ENST00000476873.1
 S100A14
 S100 calcium binding protein A14
chr12_+_6308881 1.73 ENST00000382518.1
ENST00000536586.1
 CD9
 CD9 molecule
chr1_+_152881014 1.54 ENST00000368764.3
ENST00000392667.2
 IVL
 involucrin
chr1_+_64059332 1.53 ENST00000540265.1
 PGM1
 phosphoglucomutase 1
chrX_+_131157322 1.48 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
 MST4
 Serine/threonine-protein kinase MST4
chrX_+_131157290 1.45 ENST00000394334.2
 MST4
 Serine/threonine-protein kinase MST4
chr16_+_68679193 1.44 ENST00000581171.1
 CDH3
 cadherin 3, type 1, P-cadherin (placental)
chr4_-_84030996 1.37 ENST00000411416.2
 PLAC8
 placenta-specific 8
chr1_+_169075554 1.34 ENST00000367815.4
 ATP1B1
 ATPase, Na+/K+ transporting, beta 1 polypeptide
chr18_-_11148587 1.28 ENST00000302079.6
ENST00000580640.1
ENST00000503781.3
 PIEZO2
 piezo-type mechanosensitive ion channel component 2
chr1_+_2036149 1.09 ENST00000482686.1
ENST00000400920.1
ENST00000486681.1
 PRKCZ
 protein kinase C, zeta
chr3_+_100211412 1.07 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
 TMEM45A
 transmembrane protein 45A
chr1_+_1981890 1.04 ENST00000378567.3
ENST00000468310.1
 PRKCZ
 protein kinase C, zeta
chr9_-_21974820 1.04 ENST00000579122.1
ENST00000498124.1
 CDKN2A
 cyclin-dependent kinase inhibitor 2A
chr9_+_112542591 1.03 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
 PALM2
PALM2-AKAP2
AKAP2
 paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr17_+_42429493 1.03 ENST00000586242.1
 GRN
 granulin
chr20_+_62327996 1.00 ENST00000369996.1
 TNFRSF6B
 tumor necrosis factor receptor superfamily, member 6b, decoy
chr1_-_20812690 0.98 ENST00000375078.3
 CAMK2N1
 calcium/calmodulin-dependent protein kinase II inhibitor 1
chr19_-_19739007 0.98 ENST00000586703.1
ENST00000591042.1
ENST00000407877.3
 LPAR2
 lysophosphatidic acid receptor 2
chr1_+_65613852 0.97 ENST00000327299.7
 AK4
 adenylate kinase 4
chr6_-_47277634 0.97 ENST00000296861.2
 TNFRSF21
 tumor necrosis factor receptor superfamily, member 21
chr12_+_53693466 0.94 ENST00000267103.5
ENST00000548632.1
 C12orf10
 chromosome 12 open reading frame 10
chr19_-_11689752 0.94 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
 ACP5
 acid phosphatase 5, tartrate resistant
chr16_-_68269971 0.90 ENST00000565858.1
 ESRP2
 epithelial splicing regulatory protein 2
chr12_+_7060432 0.90 ENST00000318974.9
ENST00000456013.1
 PTPN6
 protein tyrosine phosphatase, non-receptor type 6
chr10_+_124134201 0.89 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
 PLEKHA1
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr1_+_209929377 0.88 ENST00000400959.3
ENST00000367025.3
 TRAF3IP3
 TRAF3 interacting protein 3
chr14_+_65171315 0.88 ENST00000394691.1
 PLEKHG3
 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr11_+_10326612 0.88 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
 ADM
 adrenomedullin
chr3_-_124839648 0.87 ENST00000430155.2
 SLC12A8
 solute carrier family 12, member 8
chr8_+_123793633 0.86 ENST00000314393.4
 ZHX2
 zinc fingers and homeoboxes 2
chr1_+_32042105 0.84 ENST00000457433.2
ENST00000441210.2
 TINAGL1
 tubulointerstitial nephritis antigen-like 1
chr8_+_126442563 0.81 ENST00000311922.3
 TRIB1
 tribbles pseudokinase 1
chr1_+_32042131 0.81 ENST00000271064.7
ENST00000537531.1
 TINAGL1
 tubulointerstitial nephritis antigen-like 1
chr2_-_73511559 0.78 ENST00000521871.1
 FBXO41
 F-box protein 41
chr1_+_32716840 0.76 ENST00000336890.5
 LCK
 lymphocyte-specific protein tyrosine kinase
chr1_+_42921761 0.75 ENST00000372562.1
 PPCS
 phosphopantothenoylcysteine synthetase
chr2_-_220408430 0.74 ENST00000243776.6
 CHPF
 chondroitin polymerizing factor
chr1_+_40506392 0.74 ENST00000414893.1
ENST00000414281.1
ENST00000420216.1
ENST00000372792.2
ENST00000372798.1
ENST00000340450.3
ENST00000372805.3
ENST00000435719.1
ENST00000427843.1
ENST00000417287.1
ENST00000424977.1
ENST00000446031.1
 CAP1
 CAP, adenylate cyclase-associated protein 1 (yeast)
chr2_-_43453734 0.73 ENST00000282388.3
 ZFP36L2
 ZFP36 ring finger protein-like 2
chr9_-_21975038 0.73 ENST00000446177.1
 CDKN2A
 cyclin-dependent kinase inhibitor 2A
chr2_-_208030647 0.73 ENST00000309446.6
 KLF7
 Kruppel-like factor 7 (ubiquitous)
chrX_+_95939638 0.72 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
 DIAPH2
 diaphanous-related formin 2
chr2_+_234580499 0.71 ENST00000354728.4
 UGT1A9
 UDP glucuronosyltransferase 1 family, polypeptide A9
chr20_+_44746885 0.71 ENST00000372285.3
 CD40
 CD40 molecule, TNF receptor superfamily member 5
chr12_-_15114603 0.71 ENST00000228945.4
 ARHGDIB
 Rho GDP dissociation inhibitor (GDI) beta
chr20_+_44746939 0.71 ENST00000372276.3
 CD40
 CD40 molecule, TNF receptor superfamily member 5
chr4_-_169239921 0.70 ENST00000514995.1
ENST00000393743.3
 DDX60
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr12_-_15114492 0.68 ENST00000541546.1
 ARHGDIB
 Rho GDP dissociation inhibitor (GDI) beta
chr7_-_86849883 0.68 ENST00000433078.1
 TMEM243
 transmembrane protein 243, mitochondrial
chr5_-_157002775 0.68 ENST00000257527.4
 ADAM19
 ADAM metallopeptidase domain 19
chr2_+_234580525 0.67 ENST00000609637.1
 UGT1A1
 UDP glucuronosyltransferase 1 family, polypeptide A8
chr18_-_19283649 0.66 ENST00000584464.1
ENST00000578270.1
 ABHD3
 abhydrolase domain containing 3
chr14_+_65171099 0.66 ENST00000247226.7
 PLEKHG3
 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr19_+_38397839 0.65 ENST00000222345.6
 SIPA1L3
 signal-induced proliferation-associated 1 like 3
chr1_-_75198940 0.64 ENST00000417775.1
 CRYZ
 crystallin, zeta (quinone reductase)
chr21_-_45078019 0.63 ENST00000542962.1
 HSF2BP
 heat shock transcription factor 2 binding protein
chr1_+_32716857 0.61 ENST00000482949.1
ENST00000495610.2
 LCK
 lymphocyte-specific protein tyrosine kinase
chr1_-_75198681 0.61 ENST00000370872.3
ENST00000370871.3
ENST00000340866.5
ENST00000370870.1
 CRYZ
 crystallin, zeta (quinone reductase)
chrX_+_78200829 0.60 ENST00000544091.1
 P2RY10
 purinergic receptor P2Y, G-protein coupled, 10
chr20_-_56285595 0.60 ENST00000395816.3
ENST00000347215.4
 PMEPA1
 prostate transmembrane protein, androgen induced 1
chr1_+_155178518 0.59 ENST00000316721.4
 MTX1
 metaxin 1
chrX_+_78200913 0.58 ENST00000171757.2
 P2RY10
 purinergic receptor P2Y, G-protein coupled, 10
chr17_+_47448102 0.58 ENST00000576461.1
 RP11-81K2.1
 Uncharacterized protein
chr17_-_39942940 0.57 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
 JUP
 junction plakoglobin
chr7_+_94285637 0.56 ENST00000482108.1
ENST00000488574.1
 PEG10
 paternally expressed 10
chr1_+_209929494 0.56 ENST00000367026.3
 TRAF3IP3
 TRAF3 interacting protein 3
chr21_-_28217721 0.55 ENST00000284984.3
 ADAMTS1
 ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr1_-_25291475 0.55 ENST00000338888.3
ENST00000399916.1
 RUNX3
 runt-related transcription factor 3
chr3_-_49459878 0.54 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
 AMT
 aminomethyltransferase
chr9_-_21975088 0.54 ENST00000304494.5
 CDKN2A
 cyclin-dependent kinase inhibitor 2A
chr1_-_147245484 0.54 ENST00000271348.2
 GJA5
 gap junction protein, alpha 5, 40kDa
chr1_-_185286461 0.53 ENST00000367498.3
 IVNS1ABP
 influenza virus NS1A binding protein
chr1_+_155179012 0.52 ENST00000609421.1
 MTX1
 metaxin 1
chr3_-_48470838 0.52 ENST00000358459.4
ENST00000358536.4
 PLXNB1
 plexin B1
chr3_-_49459865 0.52 ENST00000427987.1
 AMT
 aminomethyltransferase
chr2_-_39347524 0.51 ENST00000395038.2
ENST00000402219.2
 SOS1
 son of sevenless homolog 1 (Drosophila)
chr17_+_12692774 0.51 ENST00000379672.5
ENST00000340825.3
 ARHGAP44
 Rho GTPase activating protein 44
chr3_-_52090461 0.50 ENST00000296483.6
ENST00000495880.1
 DUSP7
 dual specificity phosphatase 7
chr22_-_51017084 0.50 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
 CPT1B
 carnitine palmitoyltransferase 1B (muscle)
chr12_-_32908809 0.50 ENST00000324868.8
 YARS2
 tyrosyl-tRNA synthetase 2, mitochondrial
chr1_+_2398876 0.49 ENST00000449969.1
 PLCH2
 phospholipase C, eta 2
chr7_-_143105941 0.48 ENST00000275815.3
 EPHA1
 EPH receptor A1
chr5_-_150603679 0.48 ENST00000355417.2
 CCDC69
 coiled-coil domain containing 69
chr2_-_132249955 0.48 ENST00000309451.6
 MZT2A
 mitotic spindle organizing protein 2A
chr6_-_41040268 0.48 ENST00000373154.2
ENST00000244558.9
ENST00000464633.1
ENST00000424266.2
ENST00000479950.1
ENST00000482515.1
 OARD1
 O-acyl-ADP-ribose deacylase 1
chr13_-_76056250 0.47 ENST00000377636.3
ENST00000431480.2
ENST00000377625.2
ENST00000425511.1
 TBC1D4
 TBC1 domain family, member 4
chr22_-_46933067 0.45 ENST00000262738.3
ENST00000395964.1
 CELSR1
 cadherin, EGF LAG seven-pass G-type receptor 1
chr1_-_237167718 0.45 ENST00000464121.2
 MT1HL1
 metallothionein 1H-like 1
chr19_+_36195429 0.45 ENST00000392197.2
 ZBTB32
 zinc finger and BTB domain containing 32
chr1_+_182992545 0.45 ENST00000258341.4
 LAMC1
 laminin, gamma 1 (formerly LAMB2)
chr19_+_45971246 0.44 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
 FOSB
 FBJ murine osteosarcoma viral oncogene homolog B
chr1_+_153746683 0.44 ENST00000271857.2
 SLC27A3
 solute carrier family 27 (fatty acid transporter), member 3
chr8_-_21988558 0.44 ENST00000312841.8
 HR
 hair growth associated
chr4_+_78078304 0.44 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
 CCNG2
 cyclin G2
chr6_+_33589161 0.44 ENST00000605930.1
 ITPR3
 inositol 1,4,5-trisphosphate receptor, type 3
chrX_+_9983602 0.43 ENST00000380861.4
 WWC3
 WWC family member 3
chr2_-_28113965 0.43 ENST00000302188.3
 RBKS
 ribokinase
chr17_+_1646130 0.43 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
 SERPINF2
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr6_-_41040195 0.42 ENST00000463088.1
ENST00000469104.1
ENST00000486443.1
 OARD1
 O-acyl-ADP-ribose deacylase 1
chr3_+_149530836 0.42 ENST00000466478.1
ENST00000491086.1
ENST00000467977.1
 RNF13
 ring finger protein 13
chr11_-_7694684 0.41 ENST00000524790.1
ENST00000299497.9
ENST00000299498.6
 CYB5R2
 cytochrome b5 reductase 2
chr17_-_66287350 0.41 ENST00000580666.1
ENST00000583477.1
 SLC16A6
 solute carrier family 16, member 6
chr14_+_72052983 0.41 ENST00000358550.2
 SIPA1L1
 signal-induced proliferation-associated 1 like 1
chr16_+_30960375 0.40 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
 ORAI3
 ORAI calcium release-activated calcium modulator 3
chr19_+_36195467 0.40 ENST00000426659.2
 ZBTB32
 zinc finger and BTB domain containing 32
chr1_+_40505891 0.40 ENST00000372797.3
ENST00000372802.1
ENST00000449311.1
 CAP1
 CAP, adenylate cyclase-associated protein 1 (yeast)
chr19_-_45926739 0.40 ENST00000589381.1
ENST00000591636.1
ENST00000013807.5
ENST00000592023.1
 ERCC1
 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr11_-_7695437 0.40 ENST00000533558.1
ENST00000527542.1
ENST00000531096.1
 CYB5R2
 cytochrome b5 reductase 2
chr12_+_862089 0.40 ENST00000315939.6
ENST00000537687.1
ENST00000447667.2
 WNK1
 WNK lysine deficient protein kinase 1
chr5_-_157002749 0.40 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
 ADAM19
 ADAM metallopeptidase domain 19
chr20_-_50808236 0.40 ENST00000361387.2
 ZFP64
 ZFP64 zinc finger protein
chr14_+_23340822 0.39 ENST00000359591.4
 LRP10
 low density lipoprotein receptor-related protein 10
chr17_-_27405875 0.39 ENST00000359450.6
 TIAF1
 TGFB1-induced anti-apoptotic factor 1
chr19_+_45251804 0.39 ENST00000164227.5
 BCL3
 B-cell CLL/lymphoma 3
chr19_+_1067492 0.38 ENST00000586866.1
 HMHA1
 histocompatibility (minor) HA-1
chr5_+_131409476 0.38 ENST00000296871.2
 CSF2
 colony stimulating factor 2 (granulocyte-macrophage)
chrX_-_78622805 0.37 ENST00000373298.2
 ITM2A
 integral membrane protein 2A
chr1_+_155178481 0.37 ENST00000368376.3
 MTX1
 metaxin 1
chr20_-_50808290 0.37 ENST00000346617.4
ENST00000371515.4
ENST00000371518.2
 ZFP64
 ZFP64 zinc finger protein
chr8_-_145018905 0.36 ENST00000398774.2
 PLEC
 plectin
chr6_-_136871957 0.36 ENST00000354570.3
 MAP7
 microtubule-associated protein 7
chr17_-_66287257 0.36 ENST00000327268.4
 SLC16A6
 solute carrier family 16, member 6
chr16_-_10674528 0.36 ENST00000359543.3
 EMP2
 epithelial membrane protein 2
chr20_+_47538357 0.35 ENST00000371917.4
 ARFGEF2
 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr19_+_42724423 0.35 ENST00000301215.3
ENST00000597945.1
 ZNF526
 zinc finger protein 526
chr19_-_45927097 0.35 ENST00000340192.7
 ERCC1
 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr19_+_1067144 0.35 ENST00000313093.2
 HMHA1
 histocompatibility (minor) HA-1
chr19_+_35630022 0.34 ENST00000589209.1
 FXYD1
 FXYD domain containing ion transport regulator 1
chr16_+_19179549 0.34 ENST00000355377.2
ENST00000568115.1
 SYT17
 synaptotagmin XVII
chr12_-_102224704 0.34 ENST00000299314.7
 GNPTAB
 N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr2_+_42396574 0.34 ENST00000401738.3
 EML4
 echinoderm microtubule associated protein like 4
chr8_-_145047688 0.34 ENST00000356346.3
 PLEC
 plectin
chr3_+_141144954 0.32 ENST00000441582.2
ENST00000321464.5
 ZBTB38
 zinc finger and BTB domain containing 38
chr2_+_42396472 0.32 ENST00000318522.5
ENST00000402711.2
 EML4
 echinoderm microtubule associated protein like 4
chr1_+_158969752 0.32 ENST00000566111.1
 IFI16
 interferon, gamma-inducible protein 16
chr1_-_40782938 0.32 ENST00000372736.3
ENST00000372748.3
 COL9A2
 collagen, type IX, alpha 2
chr1_+_154377669 0.32 ENST00000368485.3
ENST00000344086.4
 IL6R
 interleukin 6 receptor
chr17_-_61777459 0.32 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
 LIMD2
 LIM domain containing 2
chr17_-_4871085 0.31 ENST00000575142.1
ENST00000206020.3
 SPAG7
 sperm associated antigen 7
chr13_-_25086879 0.31 ENST00000381989.3
 PARP4
 poly (ADP-ribose) polymerase family, member 4
chr17_-_8093471 0.31 ENST00000389017.4
 C17orf59
 chromosome 17 open reading frame 59
chr2_+_130939827 0.30 ENST00000409255.1
ENST00000455239.1
 MZT2B
 mitotic spindle organizing protein 2B
chr19_+_42301079 0.30 ENST00000596544.1
 CEACAM3
 carcinoembryonic antigen-related cell adhesion molecule 3
chr17_-_2304365 0.30 ENST00000575394.1
ENST00000174618.4
 MNT
 MAX network transcriptional repressor
chr19_+_1067271 0.29 ENST00000536472.1
ENST00000590214.1
 HMHA1
 histocompatibility (minor) HA-1
chr22_-_36018569 0.29 ENST00000419229.1
ENST00000406324.1
 MB
 myoglobin
chr19_+_54024251 0.29 ENST00000253144.9
 ZNF331
 zinc finger protein 331
chr15_-_44955842 0.29 ENST00000427534.2
ENST00000559193.1
ENST00000261866.7
ENST00000535302.2
ENST00000558319.1
 SPG11
 spastic paraplegia 11 (autosomal recessive)
chr17_+_18163848 0.29 ENST00000323019.4
ENST00000578174.1
ENST00000395704.4
ENST00000395703.4
ENST00000578621.1
ENST00000579341.1
 MIEF2
 mitochondrial elongation factor 2
chr1_-_21503337 0.28 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
 EIF4G3
 eukaryotic translation initiation factor 4 gamma, 3
chr21_-_43786634 0.28 ENST00000291527.2
 TFF1
 trefoil factor 1
chr19_+_35629702 0.28 ENST00000351325.4
 FXYD1
 FXYD domain containing ion transport regulator 1
chr17_-_40835076 0.28 ENST00000591765.1
 CCR10
 chemokine (C-C motif) receptor 10
chr14_+_24458123 0.28 ENST00000545240.1
ENST00000382755.4
 DHRS4L2
 dehydrogenase/reductase (SDR family) member 4 like 2
chr22_+_42229100 0.28 ENST00000361204.4
 SREBF2
 sterol regulatory element binding transcription factor 2
chrX_+_95939711 0.28 ENST00000373049.4
ENST00000324765.8
 DIAPH2
 diaphanous-related formin 2
chr17_-_10101868 0.26 ENST00000432992.2
ENST00000540214.1
 GAS7
 growth arrest-specific 7
chr13_+_28712614 0.26 ENST00000380958.3
 PAN3
 PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chrX_-_53449593 0.26 ENST00000375340.6
ENST00000322213.4
 SMC1A
 structural maintenance of chromosomes 1A
chr15_+_78730622 0.26 ENST00000560440.1
 IREB2
 iron-responsive element binding protein 2
chr19_+_7710774 0.26 ENST00000602355.1
 STXBP2
 syntaxin binding protein 2
chr19_-_19774473 0.25 ENST00000357324.6
 ATP13A1
 ATPase type 13A1
chr17_+_66511540 0.25 ENST00000588188.2
 PRKAR1A
 protein kinase, cAMP-dependent, regulatory, type I, alpha
chr8_-_2585929 0.25 ENST00000519393.1
ENST00000520842.1
ENST00000520570.1
ENST00000517357.1
ENST00000517984.1
ENST00000523971.1
 RP11-134O21.1
 RP11-134O21.1
chr7_-_27142290 0.25 ENST00000222718.5
 HOXA2
 homeobox A2
chr17_+_4613918 0.25 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
 ARRB2
 arrestin, beta 2
chrX_+_30671476 0.24 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
 GK
 glycerol kinase
chr3_-_150481164 0.24 ENST00000312960.3
 SIAH2
 siah E3 ubiquitin protein ligase 2
chr6_-_34664612 0.24 ENST00000374023.3
ENST00000374026.3
 C6orf106
 chromosome 6 open reading frame 106
chr10_+_103825080 0.24 ENST00000299238.5
 HPS6
 Hermansky-Pudlak syndrome 6
chr19_-_55866104 0.24 ENST00000326529.4
 COX6B2
 cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr13_-_39612176 0.23 ENST00000352251.3
ENST00000350125.3
 PROSER1
 proline and serine rich 1
chr14_+_24458021 0.23 ENST00000397071.1
ENST00000559411.1
ENST00000335125.6
 DHRS4L2
 dehydrogenase/reductase (SDR family) member 4 like 2
chr8_-_143867946 0.23 ENST00000301263.4
 LY6D
 lymphocyte antigen 6 complex, locus D
chr19_+_7459998 0.23 ENST00000319670.9
ENST00000599752.1
 ARHGEF18
 Rho/Rac guanine nucleotide exchange factor (GEF) 18
chr14_+_24458093 0.23 ENST00000558753.1
ENST00000537912.1
 DHRS4L2
 dehydrogenase/reductase (SDR family) member 4 like 2
chr4_-_39367949 0.22 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
 RFC1
 replication factor C (activator 1) 1, 145kDa
chr17_+_36861735 0.22 ENST00000378137.5
ENST00000325718.7
 MLLT6
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr13_-_41837620 0.22 ENST00000379477.1
ENST00000452359.1
ENST00000379480.4
ENST00000430347.2
 MTRF1
 mitochondrial translational release factor 1
chr12_-_89919965 0.22 ENST00000548729.1
 POC1B-GALNT4
 POC1B-GALNT4 readthrough
chr21_-_47575481 0.22 ENST00000291670.5
ENST00000397748.1
ENST00000359679.2
ENST00000355384.2
ENST00000397746.3
ENST00000397743.1
 FTCD
 formimidoyltransferase cyclodeaminase
chr22_+_31892373 0.22 ENST00000443011.1
ENST00000400289.1
ENST00000444859.1
ENST00000400288.2
 SFI1
 Sfi1 homolog, spindle assembly associated (yeast)
chr5_+_156693159 0.21 ENST00000347377.6
 CYFIP2
 cytoplasmic FMR1 interacting protein 2
chr14_+_92980111 0.21 ENST00000216487.7
ENST00000557762.1
 RIN3
 Ras and Rab interactor 3
chr9_+_35605274 0.21 ENST00000336395.5
 TESK1
 testis-specific kinase 1
chr12_-_57634475 0.21 ENST00000393825.1
 NDUFA4L2
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr12_+_19282713 0.21 ENST00000299275.6
ENST00000539256.1
ENST00000538714.1
 PLEKHA5
 pleckstrin homology domain containing, family A member 5
chr9_+_136325089 0.21 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
 CACFD1
 calcium channel flower domain containing 1
chr1_+_172628154 0.21 ENST00000340030.3
ENST00000367721.2
 FASLG
 Fas ligand (TNF superfamily, member 6)
chrX_+_21392529 0.20 ENST00000425654.2
ENST00000543067.1
 CNKSR2
 connector enhancer of kinase suppressor of Ras 2
chr14_+_24422795 0.20 ENST00000313250.5
ENST00000558263.1
ENST00000543741.2
ENST00000421831.1
ENST00000397073.2
ENST00000308178.8
ENST00000382761.3
ENST00000397075.3
ENST00000397074.3
ENST00000559632.1
ENST00000558581.1
 DHRS4
 dehydrogenase/reductase (SDR family) member 4
chr17_+_40834580 0.20 ENST00000264638.4
 CNTNAP1
 contactin associated protein 1
chr21_+_37692481 0.20 ENST00000400485.1
 MORC3
 MORC family CW-type zinc finger 3

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 1.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.3 1.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.3 1.3 GO:0070404 NADH binding(GO:0070404)
0.2 0.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 1.0 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 1.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.2 1.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 2.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 2.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 0.5 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.2 1.0 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.4 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 1.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.7 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 2.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.8 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 0.3 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 3.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 2.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 0.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 1.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.2 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.1 0.9 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.9 GO:0008199 ferric iron binding(GO:0008199)
0.1 1.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.3 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.6 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 1.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.8 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699) ethanol binding(GO:0035276)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.0 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 2.3 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.8 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.7 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 2.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.2 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.0 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.0 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0045179 apical cortex(GO:0045179)
0.2 2.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 1.4 GO:0043196 varicosity(GO:0043196)
0.1 0.4 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.5 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.4 GO:0005606 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.1 0.6 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.8 GO:0070522 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.1 2.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.8 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 0.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 2.7 GO:0030057 desmosome(GO:0030057)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 1.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.5 GO:0001533 cornified envelope(GO:0001533)
0.1 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 1.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.3 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 3.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.3 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 2.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 2.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 1.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.8 GO:0014704 intercalated disc(GO:0014704)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.7 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.3 GO:0031082 BLOC complex(GO:0031082)
0.0 0.1 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0032773 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.7 2.0 GO:0060166 olfactory pit development(GO:0060166)
0.6 2.3 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.5 1.5 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.4 2.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.3 1.4 GO:0071461 cellular response to redox state(GO:0071461)
0.3 1.3 GO:1903288 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
0.3 1.0 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.3 0.8 GO:0045659 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 2.7 GO:0002934 desmosome organization(GO:0002934)
0.2 0.9 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.2 1.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2 2.3 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.2 1.4 GO:0033590 response to cobalamin(GO:0033590)
0.2 0.9 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 0.6 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2 0.5 GO:0098904 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) regulation of AV node cell action potential(GO:0098904) regulation of bundle of His cell action potential(GO:0098905)
0.2 0.7 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 0.9 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.2 1.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.2 1.7 GO:0009414 response to water deprivation(GO:0009414)
0.2 0.5 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 0.4 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.4 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 1.4 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.4 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 0.4 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.8 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.1 0.6 GO:1903273 regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
0.1 1.5 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.5 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.6 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 0.3 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.7 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.5 GO:1904693 midbrain morphogenesis(GO:1904693)
0.1 1.4 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 1.4 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.1 0.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.9 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.2 GO:0021569 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 1.8 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.1 1.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.3 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.2 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.5 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.4 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.5 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.3 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1 0.3 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.2 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 1.1 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 1.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.1 GO:0033077 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.1 1.3 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1 0.2 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.3 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.6 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.0 0.2 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.9 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.4 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.2 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.0 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.4 GO:0070836 caveola assembly(GO:0070836)
0.0 0.6 GO:0006853 carnitine shuttle(GO:0006853)
0.0 1.0 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:0009078 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.0 0.6 GO:0060347 heart trabecula formation(GO:0060347)
0.0 0.9 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.3 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.1 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.2 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.0 0.1 GO:0050894 determination of affect(GO:0050894)
0.0 0.2 GO:0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 1.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.3 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 2.9 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.2 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0061113 signal transduction downstream of smoothened(GO:0007227) ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) pancreas morphogenesis(GO:0061113)
0.0 0.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 2.0 GO:0006024 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.3 GO:0061458 reproductive system development(GO:0061458)
0.0 0.1 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.3 GO:2000480 negative regulation of meiotic nuclear division(GO:0045835) negative regulation of activated T cell proliferation(GO:0046007) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.8 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.0 GO:0003335 corneocyte development(GO:0003335)
0.0 0.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.4 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 0.7 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.4 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839) venous blood vessel morphogenesis(GO:0048845)
0.0 0.7 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.4 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.0 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.3 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.0 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.4 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.1 GO:0060019 radial glial cell differentiation(GO:0060019)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 2.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 3.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.9 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 2.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 3.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 2.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.8 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 2.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 2.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 2.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 3.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.9 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 2.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.5 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.4 ST GAQ PATHWAY G alpha q Pathway