ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
TFAP4 Links Ensembl NCBI GeneCards UniProt	ENSG00000090447.7	TFAP4
MSC Links Ensembl NCBI GeneCards UniProt	ENSG00000178860.8	MSC

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TFAP4	hg19_v2_chr16_-_4323015_4323076	-0.32	2.3e-01	Click!
MSC	hg19_v2_chr8_-_72756667_72756736	0.04	8.8e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr2_-_175629135	5.54	ENST00000409542.1 ENST00000409219.1	CHRNA1	cholinergic receptor, nicotinic, alpha 1 (muscle)
chr8_-_49834299	4.82	ENST00000396822.1	SNAI2	snail family zinc finger 2
chr8_-_49833978	4.53	ENST00000020945.1	SNAI2	snail family zinc finger 2
chr5_+_102201722	4.34	ENST00000274392.9 ENST00000455264.2	PAM	peptidylglycine alpha-amidating monooxygenase
chr5_+_102201509	4.05	ENST00000348126.2 ENST00000379787.4	PAM	peptidylglycine alpha-amidating monooxygenase
chr2_-_152590946	3.69	ENST00000172853.10	NEB	nebulin
chr4_+_47487285	3.56	ENST00000273859.3 ENST00000504445.1	ATP10D	ATPase, class V, type 10D
chr4_-_52904425	3.14	ENST00000535450.1	SGCB	sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr16_+_30383613	3.13	ENST00000568749.1	MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle
chr2_+_192110199	3.13	ENST00000304164.4	MYO1B	myosin IB
chr3_+_8775466	2.95	ENST00000343849.2 ENST00000397368.2	CAV3	caveolin 3
chr5_+_102201430	2.89	ENST00000438793.3 ENST00000346918.2	PAM	peptidylglycine alpha-amidating monooxygenase
chr6_+_44184653	2.87	ENST00000573382.2 ENST00000576476.1	RP1-302G2.5	RP1-302G2.5
chr2_-_175629164	2.78	ENST00000409323.1 ENST00000261007.5 ENST00000348749.5	CHRNA1	cholinergic receptor, nicotinic, alpha 1 (muscle)
chr11_-_111783595	2.77	ENST00000528628.1	CRYAB	crystallin, alpha B
chr5_+_102201687	2.64	ENST00000304400.7	PAM	peptidylglycine alpha-amidating monooxygenase
chr3_+_159570722	2.31	ENST00000482804.1	SCHIP1	schwannomin interacting protein 1
chr5_-_16936340	2.22	ENST00000507288.1 ENST00000513610.1	MYO10	myosin X
chr1_-_86043921	2.20	ENST00000535924.2	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr5_+_135364584	2.03	ENST00000442011.2 ENST00000305126.8	TGFBI	transforming growth factor, beta-induced, 68kDa
chrX_+_135278908	2.01	ENST00000539015.1 ENST00000370683.1	FHL1	four and a half LIM domains 1
chrX_+_70521584	1.98	ENST00000373829.3 ENST00000538820.1	ITGB1BP2	integrin beta 1 binding protein (melusin) 2
chr17_+_48133459	1.91	ENST00000320031.8	ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chrX_+_135279179	1.82	ENST00000370676.3	FHL1	four and a half LIM domains 1
chr3_-_178790057	1.79	ENST00000311417.2	ZMAT3	zinc finger, matrin-type 3
chr15_+_63354769	1.78	ENST00000558910.1	TPM1	tropomyosin 1 (alpha)
chr12_-_8815299	1.77	ENST00000535336.1	MFAP5	microfibrillar associated protein 5
chr7_-_30029574	1.77	ENST00000426154.1 ENST00000421434.1 ENST00000434476.2	SCRN1	secernin 1
chr13_+_102104980	1.75	ENST00000545560.2	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)
chr12_-_50677255	1.73	ENST00000551691.1 ENST00000394943.3 ENST00000341247.4	LIMA1	LIM domain and actin binding 1
chr13_+_102104952	1.71	ENST00000376180.3	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)
chr12_-_8815215	1.69	ENST00000544889.1 ENST00000543369.1	MFAP5	microfibrillar associated protein 5
chr7_-_30029367	1.64	ENST00000242059.5	SCRN1	secernin 1
chr22_+_38071615	1.63	ENST00000215909.5	LGALS1	lectin, galactoside-binding, soluble, 1
chr2_-_190044480	1.62	ENST00000374866.3	COL5A2	collagen, type V, alpha 2
chr12_-_8814669	1.60	ENST00000535411.1 ENST00000540087.1	MFAP5	microfibrillar associated protein 5
chr19_+_16187085	1.48	ENST00000300933.4	TPM4	tropomyosin 4
chr1_-_161993422	1.47	ENST00000367940.2	OLFML2B	olfactomedin-like 2B
chr6_-_128841503	1.40	ENST00000368215.3 ENST00000532331.1 ENST00000368213.5 ENST00000368207.3 ENST00000525459.1 ENST00000368210.3 ENST00000368226.4 ENST00000368227.3	PTPRK	protein tyrosine phosphatase, receptor type, K
chr21_-_27542972	1.39	ENST00000346798.3 ENST00000439274.2 ENST00000354192.3 ENST00000348990.5 ENST00000357903.3 ENST00000358918.3 ENST00000359726.3	APP	amyloid beta (A4) precursor protein
chr11_+_32112431	1.38	ENST00000054950.3	RCN1	reticulocalbin 1, EF-hand calcium binding domain
chr13_-_33859819	1.38	ENST00000336934.5	STARD13	StAR-related lipid transfer (START) domain containing 13
chr14_+_62162258	1.36	ENST00000337138.4 ENST00000394997.1	HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr1_+_172422026	1.35	ENST00000367725.4	C1orf105	chromosome 1 open reading frame 105
chr2_-_179672142	1.35	ENST00000342992.6 ENST00000360870.5 ENST00000460472.2 ENST00000589042.1 ENST00000591111.1 ENST00000342175.6 ENST00000359218.5	TTN	titin
chr10_+_102790980	1.35	ENST00000393459.1 ENST00000224807.5	SFXN3	sideroflexin 3
chr2_+_54198210	1.33	ENST00000607452.1 ENST00000422521.2	ACYP2	acylphosphatase 2, muscle type
chr12_+_26274917	1.30	ENST00000538142.1	SSPN	sarcospan
chr3_+_69134080	1.29	ENST00000273258.3	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5
chr12_-_8815404	1.28	ENST00000359478.2 ENST00000396549.2	MFAP5	microfibrillar associated protein 5
chr8_-_145016692	1.27	ENST00000357649.2	PLEC	plectin
chr1_-_201346761	1.27	ENST00000455702.1 ENST00000422165.1 ENST00000367318.5 ENST00000367320.2 ENST00000438742.1 ENST00000412633.1 ENST00000458432.2 ENST00000421663.2 ENST00000367322.1 ENST00000509001.1	TNNT2	troponin T type 2 (cardiac)
chr3_+_69134124	1.25	ENST00000478935.1	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5
chr11_-_66084508	1.25	ENST00000311330.3	CD248	CD248 molecule, endosialin
chr16_-_79634595	1.24	ENST00000326043.4 ENST00000393350.1	MAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chrX_-_10851762	1.24	ENST00000380785.1 ENST00000380787.1	MID1	midline 1 (Opitz/BBB syndrome)
chr21_-_27543425	1.18	ENST00000448388.2	APP	amyloid beta (A4) precursor protein
chr12_-_123752624	1.17	ENST00000542174.1 ENST00000535796.1	CDK2AP1	cyclin-dependent kinase 2 associated protein 1
chr10_-_111683308	1.14	ENST00000502935.1 ENST00000322238.8 ENST00000369680.4	XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr2_-_235405168	1.13	ENST00000339728.3	ARL4C	ADP-ribosylation factor-like 4C
chr10_+_1102721	1.13	ENST00000263150.4	WDR37	WD repeat domain 37
chr14_+_90863327	1.11	ENST00000356978.4	CALM1	calmodulin 1 (phosphorylase kinase, delta)
chr11_+_111783450	1.11	ENST00000537382.1	HSPB2	Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr4_+_78079570	1.09	ENST00000509972.1	CCNG2	cyclin G2
chr3_-_99833333	1.09	ENST00000354552.3 ENST00000331335.5 ENST00000398326.2	FILIP1L	filamin A interacting protein 1-like
chr4_+_78079450	1.08	ENST00000395640.1 ENST00000512918.1	CCNG2	cyclin G2
chr6_-_24911195	1.07	ENST00000259698.4	FAM65B	family with sequence similarity 65, member B
chr17_-_1395954	1.06	ENST00000359786.5	MYO1C	myosin IC
chr2_-_225811747	1.01	ENST00000409592.3	DOCK10	dedicator of cytokinesis 10
chr11_+_111782934	1.01	ENST00000304298.3	HSPB2	Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr10_+_13142225	0.99	ENST00000378747.3	OPTN	optineurin
chr3_-_52486841	0.99	ENST00000496590.1	TNNC1	troponin C type 1 (slow)
chr2_-_152590982	0.98	ENST00000409198.1 ENST00000397345.3 ENST00000427231.2	NEB	nebulin
chr11_-_2160180	0.98	ENST00000381406.4	IGF2	insulin-like growth factor 2 (somatomedin A)
chr10_+_13142075	0.93	ENST00000378757.2 ENST00000430081.1 ENST00000378752.3 ENST00000378748.3	OPTN	optineurin
chr16_+_29831715	0.92	ENST00000563915.1 ENST00000357402.5	MVP	major vault protein
chr17_+_65040678	0.91	ENST00000226021.3	CACNG1	calcium channel, voltage-dependent, gamma subunit 1
chr3_-_81792780	0.91	ENST00000489715.1	GBE1	glucan (1,4-alpha-), branching enzyme 1
chr22_+_35776828	0.90	ENST00000216117.8	HMOX1	heme oxygenase (decycling) 1
chr7_+_48128816	0.87	ENST00000395564.4	UPP1	uridine phosphorylase 1
chr1_+_223900034	0.87	ENST00000295006.5	CAPN2	calpain 2, (m/II) large subunit
chr6_-_31697255	0.85	ENST00000436437.1	DDAH2	dimethylarginine dimethylaminohydrolase 2
chr17_+_41476327	0.84	ENST00000320033.4	ARL4D	ADP-ribosylation factor-like 4D
chr3_+_132136331	0.83	ENST00000260818.6	DNAJC13	DnaJ (Hsp40) homolog, subfamily C, member 13
chr12_-_54121212	0.83	ENST00000548263.1 ENST00000430117.2 ENST00000550804.1 ENST00000549173.1 ENST00000551900.1 ENST00000546619.1 ENST00000548177.1 ENST00000549349.1	CALCOCO1	calcium binding and coiled-coil domain 1
chr14_-_67826486	0.82	ENST00000555431.1 ENST00000554236.1 ENST00000555474.1	ATP6V1D	ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr10_-_92681033	0.80	ENST00000371697.3	ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr9_-_35111420	0.79	ENST00000378557.1	FAM214B	family with sequence similarity 214, member B
chr10_+_47746929	0.79	ENST00000340243.6 ENST00000374277.5 ENST00000449464.2 ENST00000538825.1 ENST00000335083.5	ANXA8L2 AL603965.1	annexin A8-like 2 Protein LOC100996760
chr2_-_128400788	0.78	ENST00000409286.1	LIMS2	LIM and senescent cell antigen-like domains 2
chr7_+_48128854	0.77	ENST00000436673.1 ENST00000429491.2	UPP1	uridine phosphorylase 1
chr6_-_31697563	0.76	ENST00000375789.2 ENST00000416410.1	DDAH2	dimethylarginine dimethylaminohydrolase 2
chr12_+_122150646	0.76	ENST00000449592.2	TMEM120B	transmembrane protein 120B
chr19_+_16186903	0.75	ENST00000588507.1	TPM4	tropomyosin 4
chr12_-_54121261	0.71	ENST00000549784.1 ENST00000262059.4	CALCOCO1	calcium binding and coiled-coil domain 1
chr2_+_231280908	0.71	ENST00000427101.2 ENST00000432979.1	SP100	SP100 nuclear antigen
chrX_-_107019181	0.71	ENST00000315660.4 ENST00000372384.2 ENST00000502650.1 ENST00000506724.1	TSC22D3	TSC22 domain family, member 3
chr15_-_42749711	0.69	ENST00000565611.1 ENST00000263805.4 ENST00000565948.1	ZNF106	zinc finger protein 106
chr16_-_31105870	0.69	ENST00000394971.3	VKORC1	vitamin K epoxide reductase complex, subunit 1
chr7_+_48128194	0.68	ENST00000416681.1 ENST00000331803.4 ENST00000432131.1	UPP1	uridine phosphorylase 1
chr3_-_69435224	0.67	ENST00000398540.3	FRMD4B	FERM domain containing 4B
chr19_-_46285646	0.67	ENST00000458663.2	DMPK	dystrophia myotonica-protein kinase
chr2_+_74120094	0.67	ENST00000409731.3 ENST00000345517.3 ENST00000409918.1 ENST00000442912.1 ENST00000409624.1	ACTG2	actin, gamma 2, smooth muscle, enteric
chr7_+_48128316	0.66	ENST00000341253.4	UPP1	uridine phosphorylase 1
chr1_+_153004800	0.66	ENST00000392661.3	SPRR1B	small proline-rich protein 1B
chr8_-_13134045	0.63	ENST00000512044.2	DLC1	deleted in liver cancer 1
chr5_-_95158644	0.63	ENST00000237858.6	GLRX	glutaredoxin (thioltransferase)
chr11_+_1944054	0.62	ENST00000397301.1 ENST00000397304.2 ENST00000446240.1	TNNT3	troponin T type 3 (skeletal, fast)
chr6_+_110012462	0.61	ENST00000441478.2 ENST00000230124.3	FIG4	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
chr10_-_111683183	0.59	ENST00000403138.2 ENST00000369683.1	XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr16_-_31106211	0.58	ENST00000532364.1 ENST00000529564.1 ENST00000319788.7 ENST00000354895.4 ENST00000394975.2	RP11-196G11.1 VKORC1	Uncharacterized protein vitamin K epoxide reductase complex, subunit 1
chr11_-_67120974	0.57	ENST00000539074.1 ENST00000312419.3	POLD4	polymerase (DNA-directed), delta 4, accessory subunit
chr16_-_122619	0.57	ENST00000262316.6	RHBDF1	rhomboid 5 homolog 1 (Drosophila)
chr1_+_25071848	0.57	ENST00000374379.4	CLIC4	chloride intracellular channel 4
chr19_-_46285736	0.56	ENST00000291270.4 ENST00000447742.2 ENST00000354227.5	DMPK	dystrophia myotonica-protein kinase
chr7_+_55086794	0.56	ENST00000275493.2 ENST00000442591.1	EGFR	epidermal growth factor receptor
chr11_+_33061543	0.56	ENST00000432887.1 ENST00000528898.1 ENST00000531632.2	TCP11L1	t-complex 11, testis-specific-like 1
chr12_+_49212514	0.56	ENST00000301050.2 ENST00000548279.1 ENST00000547230.1	CACNB3	calcium channel, voltage-dependent, beta 3 subunit
chr14_+_45431379	0.56	ENST00000361577.3 ENST00000361462.2 ENST00000382233.2	FAM179B	family with sequence similarity 179, member B
chr10_+_88428206	0.55	ENST00000429277.2 ENST00000458213.2 ENST00000352360.5	LDB3	LIM domain binding 3
chr20_+_62697564	0.55	ENST00000458442.1	TCEA2	transcription elongation factor A (SII), 2
chr19_-_19051103	0.55	ENST00000542541.2 ENST00000433218.2	HOMER3	homer homolog 3 (Drosophila)
chrX_-_30326445	0.55	ENST00000378963.1	NR0B1	nuclear receptor subfamily 0, group B, member 1
chr1_+_51701924	0.54	ENST00000242719.3	RNF11	ring finger protein 11
chr19_-_34012674	0.54	ENST00000436370.3 ENST00000397032.4 ENST00000244137.7	PEPD	peptidase D
chr11_-_1330834	0.53	ENST00000525159.1 ENST00000317204.6 ENST00000542915.1 ENST00000527938.1 ENST00000530541.1 ENST00000263646.7	TOLLIP	toll interacting protein
chr16_-_31106048	0.53	ENST00000300851.6	VKORC1	vitamin K epoxide reductase complex, subunit 1
chr1_+_86889769	0.53	ENST00000370565.4	CLCA2	chloride channel accessory 2
chr10_+_120863587	0.51	ENST00000535029.1 ENST00000361432.2 ENST00000544016.1	FAM45A	family with sequence similarity 45, member A
chrX_+_107069063	0.50	ENST00000262843.6	MID2	midline 2
chr17_-_7145106	0.50	ENST00000577035.1	GABARAP	GABA(A) receptor-associated protein
chr17_-_7493390	0.49	ENST00000538513.2 ENST00000570788.1 ENST00000250055.2	SOX15	SRY (sex determining region Y)-box 15
chr9_-_13165457	0.49	ENST00000542239.1 ENST00000538841.1 ENST00000433359.2	MPDZ	multiple PDZ domain protein
chr7_+_18535786	0.49	ENST00000406072.1	HDAC9	histone deacetylase 9
chr12_-_65153175	0.48	ENST00000543646.1 ENST00000542058.1 ENST00000258145.3	GNS	glucosamine (N-acetyl)-6-sulfatase
chr1_+_180165672	0.48	ENST00000443059.1	QSOX1	quiescin Q6 sulfhydryl oxidase 1
chr9_+_99212403	0.48	ENST00000375251.3 ENST00000375249.4	HABP4	hyaluronan binding protein 4
chr22_+_30792846	0.47	ENST00000312932.9 ENST00000428195.1	SEC14L2	SEC14-like 2 (S. cerevisiae)
chr9_-_35111570	0.47	ENST00000378561.1 ENST00000603301.1	FAM214B	family with sequence similarity 214, member B
chr2_+_231280954	0.45	ENST00000409824.1 ENST00000409341.1 ENST00000409112.1 ENST00000340126.4 ENST00000341950.4	SP100	SP100 nuclear antigen
chr22_+_30792980	0.45	ENST00000403484.1 ENST00000405717.3 ENST00000402592.3	SEC14L2	SEC14-like 2 (S. cerevisiae)
chr22_+_39052632	0.45	ENST00000411557.1 ENST00000396811.2 ENST00000216029.3 ENST00000416285.1	CBY1	chibby homolog 1 (Drosophila)
chr15_-_72523924	0.45	ENST00000566809.1 ENST00000567087.1 ENST00000569050.1 ENST00000568883.1	PKM	pyruvate kinase, muscle
chr6_+_30851840	0.45	ENST00000511510.1 ENST00000376569.3 ENST00000376575.3 ENST00000376570.4 ENST00000446312.1 ENST00000504927.1	DDR1	discoidin domain receptor tyrosine kinase 1
chr8_-_103668114	0.45	ENST00000285407.6	KLF10	Kruppel-like factor 10
chr2_+_234621551	0.44	ENST00000608381.1 ENST00000373414.3	UGT1A1 UGT1A5	UDP glucuronosyltransferase 1 family, polypeptide A8 UDP glucuronosyltransferase 1 family, polypeptide A5
chr11_-_1785139	0.44	ENST00000236671.2	CTSD	cathepsin D
chr9_+_17134980	0.43	ENST00000380647.3	CNTLN	centlein, centrosomal protein
chr3_+_49507559	0.43	ENST00000421560.1 ENST00000308775.2 ENST00000545947.1 ENST00000541308.1 ENST00000539901.1 ENST00000538711.1 ENST00000418588.1	DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr2_+_234602305	0.42	ENST00000406651.1	UGT1A6	UDP glucuronosyltransferase 1 family, polypeptide A6
chr6_-_132834184	0.41	ENST00000367941.2 ENST00000367937.4	STX7	syntaxin 7
chr3_-_52001448	0.41	ENST00000461554.1 ENST00000395013.3 ENST00000428823.2 ENST00000483411.1 ENST00000461544.1 ENST00000355852.2	PCBP4	poly(rC) binding protein 4
chr17_-_66453562	0.41	ENST00000262139.5 ENST00000546360.1	WIPI1	WD repeat domain, phosphoinositide interacting 1
chr7_-_41742697	0.40	ENST00000242208.4	INHBA	inhibin, beta A
chr20_-_10654639	0.38	ENST00000254958.5	JAG1	jagged 1
chr2_-_230786679	0.38	ENST00000543084.1 ENST00000343290.5 ENST00000389044.4 ENST00000283943.5	TRIP12	thyroid hormone receptor interactor 12
chr5_+_49962772	0.38	ENST00000281631.5 ENST00000513738.1 ENST00000503665.1 ENST00000514067.2 ENST00000503046.1	PARP8	poly (ADP-ribose) polymerase family, member 8
chr18_+_54318616	0.37	ENST00000254442.3	WDR7	WD repeat domain 7
chr3_+_35721106	0.37	ENST00000474696.1 ENST00000412048.1 ENST00000396482.2 ENST00000432682.1	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr11_+_1860200	0.36	ENST00000381911.1	TNNI2	troponin I type 2 (skeletal, fast)
chr6_-_117747015	0.35	ENST00000368508.3 ENST00000368507.3	ROS1	c-ros oncogene 1 , receptor tyrosine kinase
chr8_+_9413410	0.35	ENST00000520408.1 ENST00000310430.6 ENST00000522110.1	TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr15_-_77197620	0.34	ENST00000565970.1 ENST00000563290.1 ENST00000565372.1 ENST00000564177.1 ENST00000568382.1 ENST00000563919.1	SCAPER	S-phase cyclin A-associated protein in the ER
chr8_-_71519889	0.34	ENST00000521425.1	TRAM1	translocation associated membrane protein 1
chr1_+_200708671	0.34	ENST00000358823.2	CAMSAP2	calmodulin regulated spectrin-associated protein family, member 2
chr20_+_53092123	0.33	ENST00000262593.5	DOK5	docking protein 5
chr12_+_122326662	0.33	ENST00000261817.2 ENST00000538613.1 ENST00000542602.1	PSMD9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr15_+_83776137	0.33	ENST00000322019.9	TM6SF1	transmembrane 6 superfamily member 1
chr19_-_48018203	0.33	ENST00000595227.1 ENST00000593761.1 ENST00000263354.3	NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha
chr1_+_109756523	0.32	ENST00000234677.2 ENST00000369923.4	SARS	seryl-tRNA synthetase
chr15_+_49715293	0.32	ENST00000267843.4 ENST00000560270.1	FGF7	fibroblast growth factor 7
chr15_-_63448973	0.32	ENST00000462430.1	RPS27L	ribosomal protein S27-like
chr2_-_230786619	0.32	ENST00000389045.3 ENST00000409677.1	TRIP12	thyroid hormone receptor interactor 12
chr5_+_49963239	0.32	ENST00000505554.1	PARP8	poly (ADP-ribose) polymerase family, member 8
chr14_-_23288930	0.31	ENST00000554517.1 ENST00000285850.7 ENST00000397529.2 ENST00000555702.1	SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr2_-_69870747	0.31	ENST00000409068.1	AAK1	AP2 associated kinase 1
chr20_-_44485835	0.31	ENST00000457981.1 ENST00000426915.1 ENST00000217455.4	ACOT8	acyl-CoA thioesterase 8
chr4_+_142558078	0.30	ENST00000529613.1	IL15	interleukin 15
chr19_-_2151523	0.30	ENST00000350812.6 ENST00000355272.6 ENST00000356926.4 ENST00000345016.5	AP3D1	adaptor-related protein complex 3, delta 1 subunit
chr1_+_150039369	0.30	ENST00000369130.3 ENST00000369128.5	VPS45	vacuolar protein sorting 45 homolog (S. cerevisiae)
chr17_-_26989136	0.30	ENST00000247020.4	SDF2	stromal cell-derived factor 2
chr7_+_99699280	0.30	ENST00000421755.1	AP4M1	adaptor-related protein complex 4, mu 1 subunit
chr19_+_18699535	0.29	ENST00000358607.6	C19orf60	chromosome 19 open reading frame 60
chr15_+_43809797	0.29	ENST00000399453.1 ENST00000300231.5	MAP1A	microtubule-associated protein 1A
chr7_+_99699179	0.29	ENST00000438383.1 ENST00000429084.1 ENST00000359593.4 ENST00000439416.1	AP4M1	adaptor-related protein complex 4, mu 1 subunit
chr4_-_164534657	0.29	ENST00000339875.5	MARCH1	membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr17_+_58755184	0.28	ENST00000589222.1 ENST00000407086.3 ENST00000390652.5	BCAS3	breast carcinoma amplified sequence 3
chr20_+_53092232	0.28	ENST00000395939.1	DOK5	docking protein 5
chrY_+_14774265	0.27	ENST00000457658.1 ENST00000440408.1 ENST00000543097.1	TTTY15	testis-specific transcript, Y-linked 15 (non-protein coding)
chr3_+_149191723	0.27	ENST00000305354.4	TM4SF4	transmembrane 4 L six family member 4
chr17_-_1090599	0.26	ENST00000544583.2	ABR	active BCR-related
chr12_-_56122426	0.26	ENST00000551173.1	CD63	CD63 molecule
chr17_+_6347729	0.26	ENST00000572447.1	FAM64A	family with sequence similarity 64, member A
chr5_+_149569520	0.26	ENST00000230671.2 ENST00000524041.1	SLC6A7	solute carrier family 6 (neurotransmitter transporter), member 7
chr16_-_67514982	0.26	ENST00000565835.1 ENST00000540149.1 ENST00000290949.3	ATP6V0D1	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr11_+_7506713	0.25	ENST00000329293.3 ENST00000534244.1	OLFML1	olfactomedin-like 1
chr8_-_67579418	0.25	ENST00000310421.4	VCPIP1	valosin containing protein (p97)/p47 complex interacting protein 1
chr12_-_30887948	0.25	ENST00000433722.2	CAPRIN2	caprin family member 2
chr4_+_7045042	0.25	ENST00000310074.7 ENST00000512388.1	TADA2B	transcriptional adaptor 2B
chr17_+_68071458	0.25	ENST00000589377.1	KCNJ16	potassium inwardly-rectifying channel, subfamily J, member 16

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.5	13.9	GO:0018032	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
3.1	9.3	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.2	4.7	GO:0007525	somatic muscle development(GO:0007525)
1.1	4.3	GO:0035995	detection of muscle stretch(GO:0035995)
1.0	8.3	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.7	3.0	GO:0006218	uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
0.6	2.3	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
0.5	2.6	GO:0071874	cellular response to norepinephrine stimulus(GO:0071874)
0.5	1.4	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.4	1.6	GO:0002317	plasma cell differentiation(GO:0002317)
0.4	1.6	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.4	0.4	GO:0048203	vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.3	2.5	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.3	0.9	GO:0006788	heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
0.3	1.2	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.3	1.4	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.3	3.8	GO:0006527	arginine catabolic process(GO:0006527)
0.2	3.1	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.2	1.9	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.2	1.8	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
0.2	0.8	GO:1902954	regulation of early endosome to recycling endosome transport(GO:1902954)
0.2	0.6	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.2	1.8	GO:0042373	vitamin K metabolic process(GO:0042373)
0.2	0.2	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2	0.5	GO:0048627	myoblast development(GO:0048627) positive regulation of G0 to G1 transition(GO:0070318)
0.2	6.3	GO:0060216	definitive hemopoiesis(GO:0060216)
0.2	2.8	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	1.5	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	1.7	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	0.3	GO:0043314	negative regulation of neutrophil degranulation(GO:0043314)
0.1	0.4	GO:0060278	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1	0.4	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.1	0.3	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.1	3.2	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	0.7	GO:0090131	mesenchyme migration(GO:0090131)
0.1	1.0	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1	0.3	GO:0097056	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1	0.3	GO:0060437	lung growth(GO:0060437)
0.1	1.1	GO:0038089	positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089)
0.1	0.3	GO:0000821	regulation of arginine metabolic process(GO:0000821)
0.1	0.5	GO:0016476	regulation of embryonic cell shape(GO:0016476)
0.1	0.3	GO:0045062	extrathymic T cell selection(GO:0045062)
0.1	0.3	GO:0036466	synaptic vesicle recycling via endosome(GO:0036466)
0.1	0.7	GO:1902915	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.1	1.2	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	1.2	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1	2.4	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.1	0.4	GO:0070980	biphenyl catabolic process(GO:0070980)
0.1	0.7	GO:0008286	insulin receptor signaling pathway(GO:0008286)
0.1	0.6	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.1	0.6	GO:0031642	negative regulation of myelination(GO:0031642)
0.1	0.2	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.1	0.4	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.1	1.2	GO:0048535	lymph node development(GO:0048535)
0.1	0.5	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	0.4	GO:0010966	regulation of phosphate transport(GO:0010966)
0.1	0.6	GO:2000651	positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1	0.7	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.6	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.3	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.1	0.9	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.1	0.7	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.1	3.4	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.1	0.6	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.1	0.4	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	1.0	GO:2001046	positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.1	0.3	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
0.1	0.2	GO:0060168	positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1	0.3	GO:0035524	proline transmembrane transport(GO:0035524)
0.1	0.4	GO:0052697	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0	0.2	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
0.0	0.3	GO:0023021	termination of signal transduction(GO:0023021)
0.0	0.4	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.0	0.2	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.0	1.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.9	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.1	GO:0060796	regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.0	0.2	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0	0.2	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0	2.5	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.6	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	1.8	GO:0031529	ruffle organization(GO:0031529)
0.0	1.1	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.0	0.2	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.3	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.0	0.9	GO:0035994	response to muscle stretch(GO:0035994)
0.0	0.5	GO:0036010	protein localization to endosome(GO:0036010)
0.0	0.2	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.1	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	1.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.6	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.0	1.7	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.6	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	1.3	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.0	0.2	GO:0014901	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0	0.7	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.0	0.5	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.5	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.3	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.3	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.2	GO:0090161	Golgi ribbon formation(GO:0090161)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0071415	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.0	0.5	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.8	GO:0061512	protein localization to cilium(GO:0061512)
0.0	0.7	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.3	GO:0042246	tissue regeneration(GO:0042246)
0.0	0.1	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.0	0.6	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.0	1.4	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
0.0	0.1	GO:1903232	melanosome assembly(GO:1903232)
0.0	0.3	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.2	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.4	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.1	GO:0002933	lipid hydroxylation(GO:0002933)
0.0	0.4	GO:0072431	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.0	1.6	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0	0.4	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.2	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.5	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.4	GO:0010107	potassium ion import(GO:0010107)
0.0	1.5	GO:0002062	chondrocyte differentiation(GO:0002062)
0.0	0.1	GO:0070543	response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0	0.0	GO:0090675	intermicrovillar adhesion(GO:0090675)
0.0	0.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.2	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0071218	cellular response to misfolded protein(GO:0071218)
0.0	0.1	GO:0001554	luteolysis(GO:0001554)
0.0	0.2	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.1	GO:0070495	negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.0	0.1	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.6	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	8.3	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.2	3.0	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	9.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	2.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	1.8	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	3.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	0.6	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	2.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	1.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	1.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.6	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	1.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.0	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.4	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	2.2	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	2.2	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	2.0	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.6	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.7	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.6	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.6	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.2	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.3	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	1.0	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	7.5	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	8.5	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	2.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	5.6	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.1	2.6	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	4.3	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.5	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	2.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	2.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	3.5	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.6	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.2	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	1.0	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	2.6	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.9	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.5	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.7	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	1.2	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.8	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.3	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.6	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.5	13.9	GO:0004504	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.8	3.8	GO:0016403	dimethylargininase activity(GO:0016403)
0.7	3.0	GO:0004850	uridine phosphorylase activity(GO:0004850)
0.5	1.8	GO:0047057	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.4	3.0	GO:0071253	connexin binding(GO:0071253)
0.3	7.8	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.3	0.9	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.3	6.4	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.3	0.8	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.3	2.9	GO:0031013	troponin I binding(GO:0031013)
0.2	2.3	GO:0051425	PTB domain binding(GO:0051425)
0.2	1.6	GO:0070492	oligosaccharide binding(GO:0070492)
0.2	0.9	GO:0008431	vitamin E binding(GO:0008431)
0.2	1.3	GO:0003998	acylphosphatase activity(GO:0003998)
0.2	0.5	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.2	0.6	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1	14.4	GO:0008307	structural constituent of muscle(GO:0008307)
0.1	1.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	3.7	GO:0016805	dipeptidase activity(GO:0016805)
0.1	0.4	GO:0070699	type II activin receptor binding(GO:0070699)
0.1	3.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	1.4	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.6	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1	0.5	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.5	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.1	0.6	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.4	GO:0004743	pyruvate kinase activity(GO:0004743)
0.1	0.3	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.1	2.0	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.1	0.3	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.1	2.8	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	1.5	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.1	2.0	GO:0001968	fibronectin binding(GO:0001968)
0.1	8.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.7	GO:0043426	MRF binding(GO:0043426)
0.1	0.6	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	0.2	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	8.2	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1	0.3	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.3	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.2	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.4	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.4	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	0.2	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0	0.5	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.0	0.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	1.2	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.7	GO:0005112	Notch binding(GO:0005112)
0.0	1.5	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.5	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	1.0	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	1.2	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.7	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.2	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.4	GO:0031014	troponin T binding(GO:0031014)
0.0	0.3	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.2	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.3	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	4.6	GO:0005178	integrin binding(GO:0005178)
0.0	1.0	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.9	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.3	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.5	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.4	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.9	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	0.1	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0	0.1	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0	0.4	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.5	GO:0000217	DNA secondary structure binding(GO:0000217)
0.0	0.9	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.6	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.1	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	1.5	GO:0002039	p53 binding(GO:0002039)
0.0	0.7	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	2.2	GO:0044325	ion channel binding(GO:0044325)
0.0	0.2	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0	0.1	GO:0070739	NEDD8 transferase activity(GO:0019788) protein-glutamic acid ligase activity(GO:0070739)
0.0	0.6	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.0	1.3	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.1	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:0034667	integrin alpha3-beta1 complex(GO:0034667)
0.5	1.6	GO:0005588	collagen type V trimer(GO:0005588)
0.4	3.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.4	2.3	GO:1990584	cardiac Troponin complex(GO:1990584)
0.3	7.8	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.3	6.3	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.3	2.6	GO:1990812	growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.3	1.1	GO:0045160	myosin I complex(GO:0045160)
0.3	0.5	GO:0016011	dystroglycan complex(GO:0016011)
0.2	2.8	GO:0097512	cardiac myofibril(GO:0097512)
0.2	4.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.2	1.1	GO:0070545	PeBoW complex(GO:0070545)
0.2	0.6	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
0.2	4.4	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2	1.2	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.6	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.1	2.2	GO:0032433	filopodium tip(GO:0032433)
0.1	0.8	GO:0071203	WASH complex(GO:0071203)
0.1	0.5	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.1	0.3	GO:0043512	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1	3.5	GO:0005859	muscle myosin complex(GO:0005859)
0.1	0.6	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	0.7	GO:0032982	myosin filament(GO:0032982)
0.1	0.3	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1	18.6	GO:0005802	trans-Golgi network(GO:0005802)
0.1	0.5	GO:0042788	polysomal ribosome(GO:0042788)
0.1	0.2	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1	1.3	GO:0030056	hemidesmosome(GO:0030056)
0.1	1.5	GO:0031143	pseudopodium(GO:0031143)
0.1	1.0	GO:0005861	troponin complex(GO:0005861)
0.0	0.6	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.1	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0	1.2	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.4	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.3	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	0.2	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.1	GO:0031085	BLOC-3 complex(GO:0031085)
0.0	5.0	GO:0031674	I band(GO:0031674)
0.0	1.1	GO:0000922	spindle pole(GO:0000922)
0.0	0.3	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.3	GO:0005912	adherens junction(GO:0005912)
0.0	0.5	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.0	0.5	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.4	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.2	GO:0032009	early phagosome(GO:0032009)
0.0	2.1	GO:0005811	lipid particle(GO:0005811)
0.0	1.5	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	1.6	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	9.1	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.2	GO:0043234	protein complex(GO:0043234)
0.0	0.7	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.3	GO:1990752	microtubule end(GO:1990752)
0.0	0.3	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.3	GO:0033176	proton-transporting V-type ATPase complex(GO:0033176)
0.0	0.2	GO:0030914	STAGA complex(GO:0030914)
0.0	0.3	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.2	GO:0031105	septin complex(GO:0031105)
0.0	1.5	GO:0005901	caveola(GO:0005901)
0.0	0.2	GO:0031209	SCAR complex(GO:0031209)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.3	GO:0042599	lamellar body(GO:0042599)
0.0	0.8	GO:0045178	basal part of cell(GO:0045178)
0.0	1.4	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.1	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.0	0.1	GO:0043219	lateral loop(GO:0043219)
0.0	0.2	GO:0043034	costamere(GO:0043034)
0.0	0.8	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	1.1	GO:0031514	motile cilium(GO:0031514)
0.0	0.5	GO:0001533	cornified envelope(GO:0001533)