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ENCODE cell lines, expression (Ernst 2011)

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Results for TFEC_MITF_ARNTL_BHLHE41

Z-value: 0.85

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Transcription factors associated with TFEC_MITF_ARNTL_BHLHE41

Gene Symbol Gene ID Gene Info
TFEC
ENSG00000105967.11 TFEC
MITF
ENSG00000187098.10 MITF
ARNTL
ENSG00000133794.13 ARNTL
BHLHE41
ENSG00000123095.5 BHLHE41

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFEChg19_v2_chr7_-_115670804_115670867,
hg19_v2_chr7_-_115608304_115608352,
hg19_v2_chr7_-_115670792_115670798		0.421.0e-01Click!
ARNTLhg19_v2_chr11_+_13299186_132994320.361.7e-01Click!
MITFhg19_v2_chr3_+_69812877_69812962,
hg19_v2_chr3_+_69812701_69812729,
hg19_v2_chr3_+_69915385_69915438,
hg19_v2_chr3_+_69985734_69985754,
hg19_v2_chr3_+_69788576_69788648,
hg19_v2_chr3_+_69928256_69928385		0.145.9e-01Click!
BHLHE41hg19_v2_chr12_-_26278030_262780600.068.1e-01Click!

Activity profile of TFEC_MITF_ARNTL_BHLHE41 motif

Sorted Z-values of TFEC_MITF_ARNTL_BHLHE41 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFEC_MITF_ARNTL_BHLHE41

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chrX_-_34675391 4.43 ENST00000275954.3
 TMEM47
 transmembrane protein 47
chr13_+_113951607 4.20 ENST00000397181.3
 LAMP1
 lysosomal-associated membrane protein 1
chr13_+_113951532 4.02 ENST00000332556.4
 LAMP1
 lysosomal-associated membrane protein 1
chr6_+_151646800 3.19 ENST00000354675.6
 AKAP12
 A kinase (PRKA) anchor protein 12
chrX_-_100914781 3.07 ENST00000431597.1
ENST00000458024.1
ENST00000413506.1
ENST00000440675.1
ENST00000328766.5
ENST00000356824.4
 ARMCX2
 armadillo repeat containing, X-linked 2
chr3_-_49395705 2.45 ENST00000419349.1
 GPX1
 glutathione peroxidase 1
chr3_-_49395892 2.41 ENST00000419783.1
 GPX1
 glutathione peroxidase 1
chrX_+_102631844 2.37 ENST00000372634.1
ENST00000299872.7
 NGFRAP1
 nerve growth factor receptor (TNFRSF16) associated protein 1
chrX_+_102631248 2.32 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
 NGFRAP1
 nerve growth factor receptor (TNFRSF16) associated protein 1
chr9_-_79307096 2.31 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
 PRUNE2
 prune homolog 2 (Drosophila)
chr19_+_49458107 2.17 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
 BAX
 BCL2-associated X protein
chr3_+_112280857 2.14 ENST00000492406.1
ENST00000468642.1
 SLC35A5
 solute carrier family 35, member A5
chr12_+_56110247 1.99 ENST00000551926.1
 BLOC1S1
 biogenesis of lysosomal organelles complex-1, subunit 1
chr8_-_126104055 1.87 ENST00000318410.7
 KIAA0196
 KIAA0196
chr8_-_126103969 1.85 ENST00000517845.1
 KIAA0196
 KIAA0196
chr19_-_48018203 1.84 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
 NAPA
 N-ethylmaleimide-sensitive factor attachment protein, alpha
chr1_-_183604794 1.82 ENST00000367534.1
ENST00000359856.6
ENST00000294742.6
 ARPC5
 actin related protein 2/3 complex, subunit 5, 16kDa
chr17_-_46688334 1.78 ENST00000239165.7
 HOXB7
 homeobox B7
chr1_-_155211017 1.77 ENST00000536770.1
ENST00000368373.3
 GBA
 glucosidase, beta, acid
chr12_+_81110684 1.75 ENST00000228644.3
 MYF5
 myogenic factor 5
chr12_+_56109810 1.74 ENST00000550412.1
ENST00000257899.2
ENST00000548925.1
ENST00000549147.1
 RP11-644F5.10
BLOC1S1
 Uncharacterized protein
biogenesis of lysosomal organelles complex-1, subunit 1
chr7_-_27205136 1.74 ENST00000396345.1
ENST00000343483.6
 HOXA9
 homeobox A9
chr12_+_56109926 1.74 ENST00000547076.1
 BLOC1S1
 biogenesis of lysosomal organelles complex-1, subunit 1
chr1_-_155211065 1.58 ENST00000427500.3
 GBA
 glucosidase, beta, acid
chr1_-_68698222 1.58 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
 WLS
 wntless Wnt ligand secretion mediator
chr22_+_31002779 1.54 ENST00000215838.3
 TCN2
 transcobalamin II
chr1_+_183605200 1.49 ENST00000304685.4
 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
chr4_-_47465666 1.49 ENST00000381571.4
 COMMD8
 COMM domain containing 8
chr18_+_56530794 1.41 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
 ZNF532
 zinc finger protein 532
chr7_+_100464760 1.38 ENST00000200457.4
 TRIP6
 thyroid hormone receptor interactor 6
chrX_+_100663243 1.33 ENST00000316594.5
 HNRNPH2
 heterogeneous nuclear ribonucleoprotein H2 (H')
chr12_-_110434183 1.32 ENST00000360185.4
ENST00000354574.4
ENST00000338373.5
ENST00000343646.5
ENST00000356259.4
ENST00000553118.1
 GIT2
 G protein-coupled receptor kinase interacting ArfGAP 2
chr4_+_56719782 1.29 ENST00000381295.2
ENST00000346134.7
ENST00000349598.6
 EXOC1
 exocyst complex component 1
chr8_+_133787586 1.27 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
 PHF20L1
 PHD finger protein 20-like 1
chr22_+_31003133 1.19 ENST00000405742.3
 TCN2
 transcobalamin II
chr12_-_110434021 1.18 ENST00000355312.3
ENST00000551209.1
ENST00000550186.1
 GIT2
 G protein-coupled receptor kinase interacting ArfGAP 2
chr6_+_151561506 1.17 ENST00000253332.1
 AKAP12
 A kinase (PRKA) anchor protein 12
chr10_+_46222648 1.16 ENST00000336378.4
ENST00000540872.1
ENST00000537517.1
ENST00000374362.2
ENST00000359860.4
ENST00000420848.1
 FAM21C
 family with sequence similarity 21, member C
chr6_+_151561085 1.15 ENST00000402676.2
 AKAP12
 A kinase (PRKA) anchor protein 12
chr5_+_34656331 1.15 ENST00000265109.3
 RAI14
 retinoic acid induced 14
chr5_+_34656569 1.15 ENST00000428746.2
 RAI14
 retinoic acid induced 14
chrX_-_100872911 1.15 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
 ARMCX6
 armadillo repeat containing, X-linked 6
chr16_+_31044812 1.12 ENST00000313843.3
 STX4
 syntaxin 4
chr3_-_127541679 1.11 ENST00000265052.5
 MGLL
 monoglyceride lipase
chr15_+_44084040 1.09 ENST00000249786.4
 SERF2
 small EDRK-rich factor 2
chr18_+_9708162 1.08 ENST00000578921.1
 RAB31
 RAB31, member RAS oncogene family
chr1_-_154531095 1.08 ENST00000292211.4
 UBE2Q1
 ubiquitin-conjugating enzyme E2Q family member 1
chr3_+_158519654 1.04 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
 MFSD1
 major facilitator superfamily domain containing 1
chr11_-_85779971 1.03 ENST00000393346.3
 PICALM
 phosphatidylinositol binding clathrin assembly protein
chr19_+_13049413 1.02 ENST00000316448.5
ENST00000588454.1
 CALR
 calreticulin
chr16_-_67514982 0.98 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
 ATP6V0D1
 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr15_-_73925651 0.98 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
 NPTN
 neuroplastin
chr8_-_54755459 0.97 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
 ATP6V1H
 ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr11_+_18344106 0.91 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
 GTF2H1
 general transcription factor IIH, polypeptide 1, 62kDa
chr12_-_65153175 0.91 ENST00000543646.1
ENST00000542058.1
ENST00000258145.3
 GNS
 glucosamine (N-acetyl)-6-sulfatase
chr14_-_68283291 0.90 ENST00000555452.1
ENST00000347230.4
 ZFYVE26
 zinc finger, FYVE domain containing 26
chr11_+_18343800 0.89 ENST00000453096.2
 GTF2H1
 general transcription factor IIH, polypeptide 1, 62kDa
chr18_-_21977748 0.88 ENST00000399441.4
ENST00000319481.3
 OSBPL1A
 oxysterol binding protein-like 1A
chr7_-_27196267 0.88 ENST00000242159.3
 HOXA7
 homeobox A7
chr16_+_31044413 0.87 ENST00000394998.1
 STX4
 syntaxin 4
chr14_-_67826486 0.85 ENST00000555431.1
ENST00000554236.1
ENST00000555474.1
 ATP6V1D
 ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chrX_+_100878079 0.85 ENST00000471229.2
 ARMCX3
 armadillo repeat containing, X-linked 3
chr10_+_99258625 0.84 ENST00000370664.3
 UBTD1
 ubiquitin domain containing 1
chr4_-_76439483 0.83 ENST00000380840.2
ENST00000513257.1
ENST00000507014.1
 RCHY1
 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr8_-_82395461 0.83 ENST00000256104.4
 FABP4
 fatty acid binding protein 4, adipocyte
chr12_+_56110315 0.82 ENST00000548556.1
 BLOC1S1
 biogenesis of lysosomal organelles complex-1, subunit 1
chr7_-_27135591 0.81 ENST00000343060.4
ENST00000355633.5
 HOXA1
 homeobox A1
chrX_+_102883887 0.80 ENST00000372625.3
ENST00000372624.3
 TCEAL1
 transcription elongation factor A (SII)-like 1
chr1_-_31845914 0.79 ENST00000373713.2
 FABP3
 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr17_+_42422637 0.79 ENST00000053867.3
ENST00000588143.1
 GRN
 granulin
chr1_-_153508460 0.78 ENST00000462776.2
 S100A6
 S100 calcium binding protein A6
chr1_-_201476274 0.78 ENST00000340006.2
 CSRP1
 cysteine and glycine-rich protein 1
chr14_-_88459503 0.78 ENST00000393568.4
ENST00000261304.2
 GALC
 galactosylceramidase
chr19_+_40854559 0.78 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
 PLD3
 phospholipase D family, member 3
chrX_+_102840408 0.78 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
 TCEAL4
 transcription elongation factor A (SII)-like 4
chr6_-_80657292 0.77 ENST00000369816.4
 ELOVL4
 ELOVL fatty acid elongase 4
chr14_-_81687575 0.76 ENST00000434192.2
 GTF2A1
 general transcription factor IIA, 1, 19/37kDa
chr16_-_88923285 0.76 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
 GALNS
 galactosamine (N-acetyl)-6-sulfate sulfatase
chrX_+_102611373 0.75 ENST00000372661.3
ENST00000372656.3
 WBP5
 WW domain binding protein 5
chr4_-_76439596 0.74 ENST00000451788.1
ENST00000512706.1
 RCHY1
 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chrX_+_135229731 0.74 ENST00000420362.1
 FHL1
 four and a half LIM domains 1
chr5_-_121413974 0.73 ENST00000231004.4
 LOX
 lysyl oxidase
chr15_+_44084503 0.71 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
 SERF2
 small EDRK-rich factor 2
chr17_+_42422662 0.71 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
 GRN
 granulin
chr3_-_112280709 0.71 ENST00000402314.2
ENST00000283290.5
ENST00000492886.1
 ATG3
 autophagy related 3
chrX_+_55744166 0.70 ENST00000374941.4
ENST00000414239.1
 RRAGB
 Ras-related GTP binding B
chr1_+_145611010 0.70 ENST00000369291.5
 RNF115
 ring finger protein 115
chrX_+_55744228 0.70 ENST00000262850.7
 RRAGB
 Ras-related GTP binding B
chr8_+_94929168 0.69 ENST00000518107.1
ENST00000396200.3
 PDP1
 pyruvate dehyrogenase phosphatase catalytic subunit 1
chr19_-_12886327 0.68 ENST00000397668.3
ENST00000587178.1
ENST00000264827.5
 HOOK2
 hook microtubule-tethering protein 2
chr8_+_94929077 0.68 ENST00000297598.4
ENST00000520614.1
 PDP1
 pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_-_68698197 0.68 ENST00000370973.2
ENST00000370971.1
 WLS
 wntless Wnt ligand secretion mediator
chr5_-_172198190 0.68 ENST00000239223.3
 DUSP1
 dual specificity phosphatase 1
chr10_-_126716459 0.67 ENST00000309035.6
 CTBP2
 C-terminal binding protein 2
chr1_+_221051699 0.66 ENST00000366903.6
 HLX
 H2.0-like homeobox
chr1_-_241520525 0.66 ENST00000366565.1
 RGS7
 regulator of G-protein signaling 7
chr14_-_54955721 0.65 ENST00000554908.1
 GMFB
 glia maturation factor, beta
chr11_-_85779786 0.65 ENST00000356360.5
 PICALM
 phosphatidylinositol binding clathrin assembly protein
chr4_+_39184024 0.64 ENST00000399820.3
ENST00000509560.1
ENST00000512112.1
ENST00000288634.7
ENST00000506503.1
 WDR19
 WD repeat domain 19
chr22_+_31003190 0.64 ENST00000407817.3
 TCN2
 transcobalamin II
chrX_+_100805496 0.63 ENST00000372829.3
 ARMCX1
 armadillo repeat containing, X-linked 1
chr12_+_6309517 0.63 ENST00000382519.4
ENST00000009180.4
 CD9
 CD9 molecule
chr1_+_154193325 0.63 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
 UBAP2L
 ubiquitin associated protein 2-like
chrX_-_15872914 0.63 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
 AP1S2
 adaptor-related protein complex 1, sigma 2 subunit
chr19_+_11546153 0.62 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
 PRKCSH
 protein kinase C substrate 80K-H
chr17_-_57184064 0.62 ENST00000262294.7
 TRIM37
 tripartite motif containing 37
chrY_+_2709527 0.61 ENST00000250784.8
 RPS4Y1
 ribosomal protein S4, Y-linked 1
chr8_-_54755789 0.61 ENST00000359530.2
 ATP6V1H
 ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr8_+_94929110 0.60 ENST00000520728.1
 PDP1
 pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_-_241520385 0.60 ENST00000366564.1
 RGS7
 regulator of G-protein signaling 7
chr12_-_21810726 0.60 ENST00000396076.1
 LDHB
 lactate dehydrogenase B
chr11_-_2906979 0.60 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
 CDKN1C
 cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr19_+_12848299 0.60 ENST00000357332.3
 ASNA1
 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr12_-_90102594 0.60 ENST00000428670.3
 ATP2B1
 ATPase, Ca++ transporting, plasma membrane 1
chr5_+_110074685 0.59 ENST00000355943.3
ENST00000447245.2
 SLC25A46
 solute carrier family 25, member 46
chr16_+_19567016 0.59 ENST00000251143.5
ENST00000417362.2
ENST00000567245.1
ENST00000513947.4
 C16orf62
 chromosome 16 open reading frame 62
chr12_-_21810765 0.59 ENST00000450584.1
ENST00000350669.1
 LDHB
 lactate dehydrogenase B
chr2_-_133427767 0.58 ENST00000397463.2
 LYPD1
 LY6/PLAUR domain containing 1
chr9_+_103235365 0.57 ENST00000374879.4
 TMEFF1
 transmembrane protein with EGF-like and two follistatin-like domains 1
chr19_+_11546093 0.57 ENST00000591462.1
 PRKCSH
 protein kinase C substrate 80K-H
chr1_+_42921761 0.57 ENST00000372562.1
 PPCS
 phosphopantothenoylcysteine synthetase
chr3_+_147127142 0.56 ENST00000282928.4
 ZIC1
 Zic family member 1
chr19_+_11546440 0.56 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
 PRKCSH
 protein kinase C substrate 80K-H
chr12_+_14518598 0.56 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
 ATF7IP
 activating transcription factor 7 interacting protein
chr9_-_131709858 0.56 ENST00000372586.3
 DOLK
 dolichol kinase
chr12_+_53645870 0.55 ENST00000329548.4
 MFSD5
 major facilitator superfamily domain containing 5
chrY_+_22918021 0.55 ENST00000288666.5
 RPS4Y2
 ribosomal protein S4, Y-linked 2
chr7_-_42951509 0.55 ENST00000438029.1
ENST00000432637.1
ENST00000447342.1
ENST00000431882.2
ENST00000350427.4
ENST00000425683.1
 C7orf25
 chromosome 7 open reading frame 25
chr12_+_51632508 0.55 ENST00000449723.3
 DAZAP2
 DAZ associated protein 2
chr7_-_30029574 0.54 ENST00000426154.1
ENST00000421434.1
ENST00000434476.2
 SCRN1
 secernin 1
chr3_+_51428704 0.53 ENST00000323686.4
 RBM15B
 RNA binding motif protein 15B
chrY_+_2709906 0.53 ENST00000430575.1
 RPS4Y1
 ribosomal protein S4, Y-linked 1
chr7_-_30029367 0.52 ENST00000242059.5
 SCRN1
 secernin 1
chr5_+_148521381 0.52 ENST00000504238.1
 ABLIM3
 actin binding LIM protein family, member 3
chr12_-_56123444 0.52 ENST00000546457.1
ENST00000549117.1
 CD63
 CD63 molecule
chr20_+_56884752 0.51 ENST00000244040.3
 RAB22A
 RAB22A, member RAS oncogene family
chrX_+_101975643 0.51 ENST00000361229.4
 BHLHB9
 basic helix-loop-helix domain containing, class B, 9
chr12_-_56122761 0.51 ENST00000552164.1
ENST00000420846.3
ENST00000257857.4
 CD63
 CD63 molecule
chrX_+_102469997 0.51 ENST00000372695.5
ENST00000372691.3
 BEX4
 brain expressed, X-linked 4
chr14_+_105941118 0.51 ENST00000550577.1
ENST00000538259.2
 CRIP2
 cysteine-rich protein 2
chr15_-_40213080 0.50 ENST00000561100.1
 GPR176
 G protein-coupled receptor 176
chr12_+_51632600 0.50 ENST00000549555.1
ENST00000439799.2
ENST00000425012.2
 DAZAP2
 DAZ associated protein 2
chr20_+_17550691 0.50 ENST00000474024.1
 DSTN
 destrin (actin depolymerizing factor)
chr17_-_57184260 0.50 ENST00000376149.3
ENST00000393066.3
 TRIM37
 tripartite motif containing 37
chrX_+_101975619 0.50 ENST00000457056.1
 BHLHB9
 basic helix-loop-helix domain containing, class B, 9
chr2_+_242254679 0.49 ENST00000428282.1
ENST00000360051.3
 SEPT2
 septin 2
chr3_-_69062764 0.49 ENST00000295571.5
 EOGT
 EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chrX_+_102883620 0.49 ENST00000372626.3
 TCEAL1
 transcription elongation factor A (SII)-like 1
chr12_+_51632638 0.47 ENST00000549732.2
 DAZAP2
 DAZ associated protein 2
chr10_+_70883908 0.47 ENST00000263559.6
ENST00000395098.1
ENST00000546041.1
ENST00000541711.1
 VPS26A
 vacuolar protein sorting 26 homolog A (S. pombe)
chr19_+_35168633 0.47 ENST00000505365.2
 ZNF302
 zinc finger protein 302
chr8_+_74903580 0.46 ENST00000284818.2
ENST00000518893.1
 LY96
 lymphocyte antigen 96
chr8_+_22436635 0.46 ENST00000452226.1
ENST00000397760.4
ENST00000339162.7
ENST00000397761.2
 PDLIM2
 PDZ and LIM domain 2 (mystique)
chr2_+_223916862 0.45 ENST00000604125.1
 KCNE4
 potassium voltage-gated channel, Isk-related family, member 4
chr7_+_23286182 0.45 ENST00000258733.4
ENST00000381990.2
ENST00000409458.3
ENST00000539136.1
ENST00000453162.2
 GPNMB
 glycoprotein (transmembrane) nmb
chr5_-_150537279 0.45 ENST00000517486.1
ENST00000377751.5
ENST00000356496.5
ENST00000521512.1
ENST00000517757.1
ENST00000354546.5
 ANXA6
 annexin A6
chr3_-_45883558 0.45 ENST00000445698.1
ENST00000296135.6
 LZTFL1
 leucine zipper transcription factor-like 1
chr7_+_100271446 0.44 ENST00000419828.1
ENST00000427895.1
 GNB2
 guanine nucleotide binding protein (G protein), beta polypeptide 2
chr4_+_78078304 0.44 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
 CCNG2
 cyclin G2
chr17_-_17875688 0.44 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
 TOM1L2
 target of myb1-like 2 (chicken)
chr12_+_54378923 0.44 ENST00000303460.4
 HOXC10
 homeobox C10
chr10_+_51827648 0.43 ENST00000351071.6
ENST00000314664.7
ENST00000282633.5
 FAM21A
 family with sequence similarity 21, member A
chr13_+_43597269 0.43 ENST00000379221.2
 DNAJC15
 DnaJ (Hsp40) homolog, subfamily C, member 15
chr7_-_38948774 0.43 ENST00000395969.2
ENST00000414632.1
ENST00000310301.4
 VPS41
 vacuolar protein sorting 41 homolog (S. cerevisiae)
chr12_-_49318715 0.43 ENST00000444214.2
 FKBP11
 FK506 binding protein 11, 19 kDa
chr9_-_125667618 0.43 ENST00000423239.2
 RC3H2
 ring finger and CCCH-type domains 2
chr13_-_50367057 0.42 ENST00000261667.3
 KPNA3
 karyopherin alpha 3 (importin alpha 4)
chrX_+_10124977 0.42 ENST00000380833.4
 CLCN4
 chloride channel, voltage-sensitive 4
chr9_-_21995300 0.42 ENST00000498628.2
 CDKN2A
 cyclin-dependent kinase inhibitor 2A
chr1_+_42922173 0.41 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
 PPCS
 phosphopantothenoylcysteine synthetase
chr10_-_93392811 0.41 ENST00000238994.5
 PPP1R3C
 protein phosphatase 1, regulatory subunit 3C
chr21_-_46237959 0.41 ENST00000397898.3
ENST00000411651.2
 SUMO3
 small ubiquitin-like modifier 3
chr3_+_134204551 0.41 ENST00000332047.5
ENST00000354446.3
 CEP63
 centrosomal protein 63kDa
chr9_-_135819987 0.41 ENST00000298552.3
ENST00000403810.1
 TSC1
 tuberous sclerosis 1
chr22_-_17640110 0.40 ENST00000399852.3
ENST00000336737.4
 CECR5
 cat eye syndrome chromosome region, candidate 5
chr8_+_22436248 0.40 ENST00000308354.7
 PDLIM2
 PDZ and LIM domain 2 (mystique)
chr11_-_47470591 0.40 ENST00000524487.1
 RAPSN
 receptor-associated protein of the synapse
chr7_-_27183263 0.40 ENST00000222726.3
 HOXA5
 homeobox A5
chr17_-_35969409 0.40 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
 SYNRG
 synergin, gamma
chr22_+_35776828 0.40 ENST00000216117.8
 HMOX1
 heme oxygenase (decycling) 1
chr14_-_69445793 0.40 ENST00000538545.2
ENST00000394419.4
 ACTN1
 actinin, alpha 1
chrX_-_9734004 0.39 ENST00000467482.1
ENST00000380929.2
 GPR143
 G protein-coupled receptor 143
chr12_+_69139886 0.38 ENST00000398004.2
 SLC35E3
 solute carrier family 35, member E3
chr1_-_39325431 0.38 ENST00000373001.3
 RRAGC
 Ras-related GTP binding C
chr1_-_27998689 0.38 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
 IFI6
 interferon, alpha-inducible protein 6
chr4_+_76439665 0.38 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
 THAP6
 THAP domain containing 6
chr12_+_12878829 0.38 ENST00000326765.6
 APOLD1
 apolipoprotein L domain containing 1
chr11_-_47470703 0.38 ENST00000298854.2
 RAPSN
 receptor-associated protein of the synapse
chr2_-_197036289 0.38 ENST00000263955.4
 STK17B
 serine/threonine kinase 17b
chr1_-_26233423 0.38 ENST00000357865.2
 STMN1
 stathmin 1
chr11_-_61560053 0.37 ENST00000537328.1
 TMEM258
 transmembrane protein 258
chr15_+_75628232 0.37 ENST00000267935.8
ENST00000567195.1
 COMMD4
 COMM domain containing 4
chr11_-_61560254 0.37 ENST00000543510.1
 TMEM258
 transmembrane protein 258
chr11_-_85780086 0.37 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
 PICALM
 phosphatidylinositol binding clathrin assembly protein
chr2_+_242254507 0.37 ENST00000391973.2
 SEPT2
 septin 2
chr6_+_127587755 0.37 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
 RNF146
 ring finger protein 146
chr17_+_17876127 0.37 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
 LRRC48
 leucine rich repeat containing 48
chr9_+_115913222 0.37 ENST00000259392.3
 SLC31A2
 solute carrier family 31 (copper transporter), member 2
chr10_-_14050522 0.37 ENST00000342409.2
 FRMD4A
 FERM domain containing 4A
chr12_+_51633061 0.37 ENST00000551313.1
 DAZAP2
 DAZ associated protein 2

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 1.2 REACTOME TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT Genes involved in The citric acid (TCA) cycle and respiratory electron transport
0.2 8.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 2.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 3.1 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 2.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.2 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.1 0.7 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 3.8 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 2.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 2.0 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.5 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 4.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 2.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 8.4 GO:0097208 alveolar lamellar body(GO:0097208)
0.5 4.6 GO:0097413 Lewy body(GO:0097413)
0.5 1.8 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.3 6.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.3 2.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.3 1.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.3 1.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.3 1.8 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 1.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.2 2.0 GO:0000322 storage vacuole(GO:0000322)
0.2 2.0 GO:0000439 core TFIIH complex(GO:0000439)
0.2 1.0 GO:0033263 CORVET complex(GO:0033263)
0.2 0.7 GO:0070695 FHF complex(GO:0070695)
0.2 2.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.0 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.9 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.3 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 1.1 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.1 1.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 2.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.0 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.1 GO:0005916 fascia adherens(GO:0005916)
0.1 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.1 0.4 GO:0005901 caveola(GO:0005901)
0.1 0.2 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.9 GO:0097227 sperm annulus(GO:0097227)
0.1 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.7 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1 0.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.3 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 0.4 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.3 GO:0033503 HULC complex(GO:0033503)
0.1 0.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.6 GO:0030478 actin cap(GO:0030478)
0.0 7.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.7 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.6 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 1.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 2.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0032155 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 8.1 GO:0005938 cell cortex(GO:0005938)
0.0 1.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 1.4 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.6 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.2 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.0 GO:0044308 axonal spine(GO:0044308)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.3 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.4 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.5 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:0097342 ripoptosome(GO:0097342)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.0 GO:0031082 BLOC complex(GO:0031082)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.2 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
1.0 4.9 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.8 3.4 GO:1904457 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.8 6.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.7 2.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.7 2.2 GO:1902445 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) positive regulation of apoptotic DNA fragmentation(GO:1902512) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.7 2.0 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.4 1.1 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.4 1.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.4 5.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.3 1.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.3 3.3 GO:0015889 cobalamin transport(GO:0015889)
0.3 1.8 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.3 2.1 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.3 1.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.3 0.3 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.3 0.8 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.3 0.8 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.2 1.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2 0.6 GO:0061055 myotome development(GO:0061055)
0.2 0.9 GO:1902544 oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
0.2 0.8 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.2 1.4 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.2 0.6 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.2 2.1 GO:0042118 endothelial cell activation(GO:0042118)
0.2 1.8 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.2 0.5 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 1.0 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.2 1.7 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.2 1.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 2.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 0.9 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.6 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.1 0.1 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.7 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.1 0.4 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.1 0.4 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.1 0.4 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
0.1 0.4 GO:2000777 positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1 0.9 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.6 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.2 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.1 0.6 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.1 GO:0006623 protein targeting to vacuole(GO:0006623)
0.1 1.3 GO:0051601 exocyst localization(GO:0051601)
0.1 0.3 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 0.4 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.4 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 4.4 GO:0090382 phagosome maturation(GO:0090382)
0.1 0.4 GO:1902908 regulation of melanosome transport(GO:1902908)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.6 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.6 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.6 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.9 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.7 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.3 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 0.4 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.1 0.4 GO:0000189 MAPK import into nucleus(GO:0000189)
0.1 0.7 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.3 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 1.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.6 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 0.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.2 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.1 0.4 GO:0090649 rRNA transport(GO:0051029) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.8 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 0.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 1.0 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 0.2 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.2 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.3 GO:0009386 translational attenuation(GO:0009386)
0.1 0.4 GO:1902957 negative regulation of cellular respiration(GO:1901856) negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.1 0.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.2 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.8 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.3 GO:0090269 fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
0.1 0.8 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.1 0.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 2.0 GO:0006295 nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.7 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.2 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 1.0 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.1 1.8 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.8 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.4 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 0.8 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 1.8 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.5 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.3 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.3 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 0.2 GO:0072683 T cell extravasation(GO:0072683)
0.1 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.2 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.2 GO:0035606 induction of programmed cell death(GO:0012502) peptidyl-cysteine S-trans-nitrosylation(GO:0035606) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.1 0.4 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.3 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0060592 mammary gland formation(GO:0060592)
0.0 0.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.9 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.7 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.4 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.7 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.3 GO:0051036 regulation of endosome size(GO:0051036)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0002429 immune response-activating cell surface receptor signaling pathway(GO:0002429)
0.0 0.2 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.4 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 0.2 GO:2001137 positive regulation of actin filament depolymerization(GO:0030836) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) positive regulation of endocytic recycling(GO:2001137)
0.0 0.2 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0015883 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.2 GO:0098502 DNA dephosphorylation(GO:0098502)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.9 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.0 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.4 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.4 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.2 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.1 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.4 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.6 GO:0098926 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.5 GO:0034030 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.1 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.6 GO:0007628 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0 0.1 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.4 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.0 0.2 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 1.1 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.6 GO:0007565 female pregnancy(GO:0007565)
0.0 0.8 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.3 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.6 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 1.1 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097)
0.0 2.1 GO:0015992 proton transport(GO:0015992)
0.0 0.0 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 1.1 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.8 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.8 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.4 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.6 GO:0010761 fibroblast migration(GO:0010761)
0.0 2.1 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.7 GO:0048512 circadian behavior(GO:0048512)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.0 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.3 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.4 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0000715 protein deneddylation(GO:0000338) nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.0 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.3 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0071468 cellular response to acidic pH(GO:0071468)
0.0 0.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.2 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.0 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0033572 transferrin transport(GO:0033572)
0.0 0.1 GO:0006068 ethanol metabolic process(GO:0006067) ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.4 GO:0004348 glucosylceramidase activity(GO:0004348)
0.5 2.0 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.5 1.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 5.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 1.9 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 3.4 GO:0031419 cobalamin binding(GO:0031419)
0.3 0.9 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.3 0.8 GO:0070538 oleic acid binding(GO:0070538)
0.2 1.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 2.2 GO:0051434 BH3 domain binding(GO:0051434)
0.2 1.2 GO:0004630 phospholipase D activity(GO:0004630)
0.2 2.4 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.2 2.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 1.2 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.2 0.5 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.2 4.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 2.1 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.1 0.4 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.4 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.7 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.4 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 0.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.6 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.6 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.3 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.7 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 4.0 GO:0050699 WW domain binding(GO:0050699)
0.1 1.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.0 GO:0031386 protein tag(GO:0031386)
0.1 1.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.2 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 8.5 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 1.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.1 GO:0043495 protein anchor(GO:0043495)
0.1 1.4 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.2 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.1 1.2 GO:0017166 vinculin binding(GO:0017166)
0.1 1.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 0.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.2 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 1.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0035500 MH2 domain binding(GO:0035500)
0.0 1.1 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.3 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.4 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0019828 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.8 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0 0.2 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.4 GO:0035240 dopamine binding(GO:0035240)
0.0 1.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.0 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 1.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.0 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.0 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 1.4 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.3 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.6 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.0 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 1.2 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.5 GO:0008565 protein transporter activity(GO:0008565)
0.0 2.1 GO:0044325 ion channel binding(GO:0044325)
0.0 0.7 GO:0005507 copper ion binding(GO:0005507)
0.0 0.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.0 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 1.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.0 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 4.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 4.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 6.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.3 PID INSULIN PATHWAY Insulin Pathway
0.0 2.7 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.9 ST GAQ PATHWAY G alpha q Pathway
0.0 1.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 2.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events