ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
TGIF1 Links Ensembl NCBI GeneCards UniProt	ENSG00000177426.16	TGIF1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TGIF1	hg19_v2_chr18_+_3451646_3451722	-0.29	2.8e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr2_+_33359646	3.70	ENST00000390003.4 ENST00000418533.2	LTBP1	latent transforming growth factor beta binding protein 1
chr2_+_33359687	3.68	ENST00000402934.1 ENST00000404525.1 ENST00000407925.1	LTBP1	latent transforming growth factor beta binding protein 1
chr3_-_127541679	3.45	ENST00000265052.5	MGLL	monoglyceride lipase
chr4_+_55095264	3.45	ENST00000257290.5	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide
chr3_-_127541194	3.06	ENST00000453507.2	MGLL	monoglyceride lipase
chr3_-_127542021	2.80	ENST00000434178.2	MGLL	monoglyceride lipase
chr3_-_127542051	2.79	ENST00000398104.1	MGLL	monoglyceride lipase
chr18_+_54318616	2.77	ENST00000254442.3	WDR7	WD repeat domain 7
chr18_+_54318566	2.62	ENST00000589935.1 ENST00000357574.3	WDR7	WD repeat domain 7
chr15_-_48937982	2.53	ENST00000316623.5	FBN1	fibrillin 1
chr17_+_68165657	2.13	ENST00000243457.3	KCNJ2	potassium inwardly-rectifying channel, subfamily J, member 2
chr9_+_125133315	2.08	ENST00000223423.4 ENST00000362012.2	PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr3_+_45067659	2.07	ENST00000296130.4	CLEC3B	C-type lectin domain family 3, member B
chr22_-_37640277	2.02	ENST00000401529.3 ENST00000249071.6	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr18_-_52969844	1.93	ENST00000561831.3	TCF4	transcription factor 4
chr17_-_46623441	1.86	ENST00000330070.4	HOXB2	homeobox B2
chr19_-_36643329	1.84	ENST00000589154.1	COX7A1	cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr7_-_93520259	1.82	ENST00000222543.5	TFPI2	tissue factor pathway inhibitor 2
chr5_+_141348640	1.75	ENST00000540015.1 ENST00000506938.1 ENST00000394514.2 ENST00000512565.1 ENST00000394515.3	RNF14	ring finger protein 14
chr18_-_52989525	1.75	ENST00000457482.3	TCF4	transcription factor 4
chr13_-_38172863	1.70	ENST00000541481.1 ENST00000379743.4 ENST00000379742.4 ENST00000379749.4 ENST00000541179.1 ENST00000379747.4	POSTN	periostin, osteoblast specific factor
chr4_+_77870960	1.62	ENST00000505788.1 ENST00000510515.1 ENST00000504637.1	SEPT11	septin 11
chr9_+_125132803	1.61	ENST00000540753.1	PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr7_-_137028534	1.58	ENST00000348225.2	PTN	pleiotrophin
chrX_-_48931648	1.58	ENST00000376386.3 ENST00000376390.4	PRAF2	PRA1 domain family, member 2
chr7_-_137028498	1.57	ENST00000393083.2	PTN	pleiotrophin
chr5_+_141348721	1.56	ENST00000507163.1 ENST00000394519.1	RNF14	ring finger protein 14
chr11_+_12132117	1.51	ENST00000256194.4	MICAL2	microtubule associated monooxygenase, calponin and LIM domain containing 2
chr21_+_30502806	1.50	ENST00000399928.1 ENST00000399926.1	MAP3K7CL	MAP3K7 C-terminal like
chr5_-_94620239	1.48	ENST00000515393.1	MCTP1	multiple C2 domains, transmembrane 1
chr11_+_6411636	1.47	ENST00000299397.3 ENST00000356761.2 ENST00000342245.4	SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal
chr7_-_93520191	1.44	ENST00000545378.1	TFPI2	tissue factor pathway inhibitor 2
chr14_-_100842588	1.42	ENST00000556645.1 ENST00000556209.1 ENST00000556504.1 ENST00000556435.1 ENST00000554772.1 ENST00000553581.1 ENST00000553769.2 ENST00000554605.1 ENST00000557722.1 ENST00000553413.1 ENST00000553524.1 ENST00000358655.4	WARS	tryptophanyl-tRNA synthetase
chr1_+_163038565	1.41	ENST00000421743.2	RGS4	regulator of G-protein signaling 4
chr17_-_76899275	1.40	ENST00000322630.2 ENST00000586713.1	DDC8	Protein DDC8 homolog
chr9_+_116207007	1.38	ENST00000374140.2	RGS3	regulator of G-protein signaling 3
chr5_+_76011868	1.32	ENST00000319211.4	F2R	coagulation factor II (thrombin) receptor
chr2_-_235405168	1.31	ENST00000339728.3	ARL4C	ADP-ribosylation factor-like 4C
chr8_-_93029865	1.25	ENST00000422361.2	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr18_-_21891460	1.24	ENST00000357041.4	OSBPL1A	oxysterol binding protein-like 1A
chr9_-_16727978	1.22	ENST00000418777.1 ENST00000468187.2	BNC2	basonuclin 2
chr1_+_186798073	1.20	ENST00000367466.3 ENST00000442353.2	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr18_+_66465302	1.18	ENST00000360242.5 ENST00000358653.5	CCDC102B	coiled-coil domain containing 102B
chr11_-_64052111	1.16	ENST00000394532.3 ENST00000394531.3 ENST00000309032.3	BAD	BCL2-associated agonist of cell death
chr8_+_22446763	1.14	ENST00000450780.2 ENST00000430850.2 ENST00000447849.1	AC037459.4	Uncharacterized protein
chr16_+_31044413	1.14	ENST00000394998.1	STX4	syntaxin 4
chr3_+_112280857	1.14	ENST00000492406.1 ENST00000468642.1	SLC35A5	solute carrier family 35, member A5
chr3_+_69788576	1.11	ENST00000352241.4 ENST00000448226.2	MITF	microphthalmia-associated transcription factor
chr10_+_70748487	1.07	ENST00000361983.4	KIAA1279	KIAA1279
chr1_-_98386543	1.07	ENST00000423006.2 ENST00000370192.3 ENST00000306031.5	DPYD	dihydropyrimidine dehydrogenase
chr8_+_94929110	1.06	ENST00000520728.1	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr2_+_33661382	1.05	ENST00000402538.3	RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr22_-_37640456	1.05	ENST00000405484.1 ENST00000441619.1 ENST00000406508.1	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr8_+_94929077	1.04	ENST00000297598.4 ENST00000520614.1	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr8_-_49834299	1.03	ENST00000396822.1	SNAI2	snail family zinc finger 2
chr1_+_221051699	0.98	ENST00000366903.6	HLX	H2.0-like homeobox
chr17_-_53809473	0.95	ENST00000575734.1	TMEM100	transmembrane protein 100
chr8_-_49833978	0.95	ENST00000020945.1	SNAI2	snail family zinc finger 2
chr5_+_141348598	0.94	ENST00000394520.2 ENST00000347642.3	RNF14	ring finger protein 14
chr7_+_120591170	0.94	ENST00000431467.1	ING3	inhibitor of growth family, member 3
chr1_+_150039369	0.93	ENST00000369130.3 ENST00000369128.5	VPS45	vacuolar protein sorting 45 homolog (S. cerevisiae)
chr1_-_149889382	0.92	ENST00000369145.1 ENST00000369146.3	SV2A	synaptic vesicle glycoprotein 2A
chr2_+_185463093	0.91	ENST00000302277.6	ZNF804A	zinc finger protein 804A
chr5_+_140868717	0.90	ENST00000252087.1	PCDHGC5	protocadherin gamma subfamily C, 5
chr11_+_6411670	0.89	ENST00000530395.1 ENST00000527275.1	SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal
chr1_+_101702417	0.88	ENST00000305352.6	S1PR1	sphingosine-1-phosphate receptor 1
chr5_+_125758813	0.88	ENST00000285689.3 ENST00000515200.1	GRAMD3	GRAM domain containing 3
chr16_+_31044812	0.88	ENST00000313843.3	STX4	syntaxin 4
chrX_+_155110956	0.88	ENST00000286448.6 ENST00000262640.6 ENST00000460621.1	VAMP7	vesicle-associated membrane protein 7
chr7_-_94285472	0.87	ENST00000437425.2 ENST00000447873.1 ENST00000415788.2	SGCE	sarcoglycan, epsilon
chr8_-_42065075	0.87	ENST00000429089.2 ENST00000519510.1 ENST00000429710.2 ENST00000524009.1	PLAT	plasminogen activator, tissue
chr1_+_36621697	0.87	ENST00000373150.4 ENST00000373151.2	MAP7D1	MAP7 domain containing 1
chr5_+_34757309	0.86	ENST00000397449.1	RAI14	retinoic acid induced 14
chr18_-_54318353	0.84	ENST00000590954.1 ENST00000540155.1	TXNL1	thioredoxin-like 1
chr10_-_90751038	0.84	ENST00000458159.1 ENST00000415557.1 ENST00000458208.1	ACTA2	actin, alpha 2, smooth muscle, aorta
chr9_-_130635741	0.82	ENST00000223836.10	AK1	adenylate kinase 1
chr7_+_30951461	0.81	ENST00000311813.4	AQP1	aquaporin 1 (Colton blood group)
chr19_-_39826639	0.81	ENST00000602185.1 ENST00000598034.1 ENST00000601387.1 ENST00000595636.1 ENST00000253054.8 ENST00000594700.1 ENST00000597595.1	GMFG	glia maturation factor, gamma
chr3_-_123339343	0.81	ENST00000578202.1	MYLK	myosin light chain kinase
chr4_-_149365827	0.80	ENST00000344721.4	NR3C2	nuclear receptor subfamily 3, group C, member 2
chrX_-_153775426	0.79	ENST00000393562.2	G6PD	glucose-6-phosphate dehydrogenase
chr10_-_79398250	0.78	ENST00000286627.5	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr8_+_94929969	0.78	ENST00000517764.1	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr15_-_55562582	0.78	ENST00000396307.2	RAB27A	RAB27A, member RAS oncogene family
chr17_-_7297519	0.77	ENST00000576362.1 ENST00000571078.1	TMEM256-PLSCR3	TMEM256-PLSCR3 readthrough (NMD candidate)
chr19_-_10121144	0.77	ENST00000264828.3	COL5A3	collagen, type V, alpha 3
chr3_-_18466026	0.76	ENST00000417717.2	SATB1	SATB homeobox 1
chr17_-_26220366	0.76	ENST00000460380.2 ENST00000508862.1 ENST00000379102.3 ENST00000582441.1	LYRM9 RP1-66C13.4	LYR motif containing 9 Uncharacterized protein
chr3_-_189840223	0.75	ENST00000427335.2	LEPREL1	leprecan-like 1
chr7_-_94285511	0.75	ENST00000265735.7	SGCE	sarcoglycan, epsilon
chr1_-_33168336	0.74	ENST00000373484.3	SYNC	syncoilin, intermediate filament protein
chr9_-_130637244	0.74	ENST00000373156.1	AK1	adenylate kinase 1
chr7_-_94285402	0.74	ENST00000428696.2 ENST00000445866.2	SGCE	sarcoglycan, epsilon
chr5_+_32788945	0.74	ENST00000326958.1	AC026703.1	AC026703.1
chr11_+_842928	0.73	ENST00000397408.1	TSPAN4	tetraspanin 4
chr15_-_55562479	0.72	ENST00000564609.1	RAB27A	RAB27A, member RAS oncogene family
chr17_-_7297833	0.72	ENST00000571802.1 ENST00000576201.1 ENST00000573213.1 ENST00000324822.11	TMEM256-PLSCR3	TMEM256-PLSCR3 readthrough (NMD candidate)
chr9_+_34652164	0.72	ENST00000441545.2 ENST00000553620.1	IL11RA	interleukin 11 receptor, alpha
chr11_-_111781454	0.72	ENST00000533280.1	CRYAB	crystallin, alpha B
chr8_-_82395461	0.71	ENST00000256104.4	FABP4	fatty acid binding protein 4, adipocyte
chr11_+_842808	0.68	ENST00000397397.2 ENST00000397411.2 ENST00000397396.1	TSPAN4	tetraspanin 4
chr5_+_125758865	0.68	ENST00000542322.1 ENST00000544396.1	GRAMD3	GRAM domain containing 3
chr9_-_100459639	0.67	ENST00000375128.4	XPA	xeroderma pigmentosum, complementation group A
chr20_-_32308028	0.67	ENST00000409299.3 ENST00000217398.3 ENST00000344022.3	PXMP4	peroxisomal membrane protein 4, 24kDa
chr11_-_111781610	0.67	ENST00000525823.1	CRYAB	crystallin, alpha B
chr10_-_75255668	0.66	ENST00000545874.1	PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme
chr17_-_66951474	0.66	ENST00000269080.2	ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8
chr11_-_26743546	0.66	ENST00000280467.6 ENST00000396005.3	SLC5A12	solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr11_-_842509	0.66	ENST00000322028.4	POLR2L	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
chr1_-_35450897	0.64	ENST00000373337.3	ZMYM6NB	ZMYM6 neighbor
chr8_-_6420930	0.63	ENST00000325203.5	ANGPT2	angiopoietin 2
chr7_+_77469439	0.63	ENST00000450574.1 ENST00000416283.2 ENST00000248550.7	PHTF2	putative homeodomain transcription factor 2
chr2_-_145275228	0.63	ENST00000427902.1 ENST00000409487.3 ENST00000470879.1 ENST00000435831.1	ZEB2	zinc finger E-box binding homeobox 2
chr7_+_134551583	0.62	ENST00000435928.1	CALD1	caldesmon 1
chr1_-_186649543	0.61	ENST00000367468.5	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr8_-_6420777	0.61	ENST00000415216.1	ANGPT2	angiopoietin 2
chr12_+_104458235	0.60	ENST00000229330.4	HCFC2	host cell factor C2
chr10_-_14372870	0.60	ENST00000357447.2	FRMD4A	FERM domain containing 4A
chr8_-_57358432	0.60	ENST00000517415.1 ENST00000314922.3	PENK	proenkephalin
chr6_-_31651817	0.60	ENST00000375863.3 ENST00000375860.2	LY6G5C	lymphocyte antigen 6 complex, locus G5C
chr16_+_50776021	0.58	ENST00000566679.2 ENST00000564634.1 ENST00000398568.2	CYLD	cylindromatosis (turban tumor syndrome)
chr12_+_62654155	0.57	ENST00000312635.6 ENST00000393654.3 ENST00000549237.1	USP15	ubiquitin specific peptidase 15
chr1_+_100111580	0.56	ENST00000605497.1	PALMD	palmdelphin
chr7_-_42276612	0.56	ENST00000395925.3 ENST00000437480.1	GLI3	GLI family zinc finger 3
chr14_-_105635090	0.55	ENST00000331782.3 ENST00000347004.2	JAG2	jagged 2
chr2_+_242089833	0.54	ENST00000404405.3 ENST00000439916.1 ENST00000406106.3 ENST00000401987.1	PPP1R7	protein phosphatase 1, regulatory subunit 7
chr6_-_134639180	0.53	ENST00000367858.5	SGK1	serum/glucocorticoid regulated kinase 1
chr5_-_132112921	0.52	ENST00000378721.4 ENST00000378701.1	SEPT8	septin 8
chr3_-_112280709	0.52	ENST00000402314.2 ENST00000283290.5 ENST00000492886.1	ATG3	autophagy related 3
chr5_-_132112907	0.52	ENST00000458488.2	SEPT8	septin 8
chr1_-_193075180	0.52	ENST00000367440.3	GLRX2	glutaredoxin 2
chr22_+_41347363	0.51	ENST00000216225.8	RBX1	ring-box 1, E3 ubiquitin protein ligase
chr10_+_6244829	0.50	ENST00000317350.4 ENST00000379785.1 ENST00000379782.3 ENST00000360521.2 ENST00000379775.4	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr1_-_150669500	0.50	ENST00000271732.3	GOLPH3L	golgi phosphoprotein 3-like
chr12_-_4647606	0.49	ENST00000261250.3 ENST00000541014.1 ENST00000545746.1 ENST00000542080.1	C12orf4	chromosome 12 open reading frame 4
chr14_+_90864504	0.49	ENST00000544280.2	CALM1	calmodulin 1 (phosphorylase kinase, delta)
chr10_-_48438974	0.49	ENST00000224605.2	GDF10	growth differentiation factor 10
chr8_+_28174649	0.49	ENST00000301908.3	PNOC	prepronociceptin
chr22_+_39052632	0.48	ENST00000411557.1 ENST00000396811.2 ENST00000216029.3 ENST00000416285.1	CBY1	chibby homolog 1 (Drosophila)
chr11_+_128634589	0.47	ENST00000281428.8	FLI1	Fli-1 proto-oncogene, ETS transcription factor
chr15_-_37392086	0.47	ENST00000561208.1	MEIS2	Meis homeobox 2
chr12_+_59989791	0.47	ENST00000552432.1	SLC16A7	solute carrier family 16 (monocarboxylate transporter), member 7
chr2_-_172750733	0.47	ENST00000392592.4 ENST00000422440.2	SLC25A12	solute carrier family 25 (aspartate/glutamate carrier), member 12
chr17_+_40985407	0.46	ENST00000586114.1 ENST00000590720.1 ENST00000585805.1 ENST00000541124.1 ENST00000441946.2 ENST00000591152.1 ENST00000589469.1 ENST00000293362.3 ENST00000592169.1	PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr12_-_49318715	0.45	ENST00000444214.2	FKBP11	FK506 binding protein 11, 19 kDa
chr17_-_7145475	0.43	ENST00000571129.1 ENST00000571253.1 ENST00000573928.1	GABARAP	GABA(A) receptor-associated protein
chr11_-_111781554	0.43	ENST00000526167.1 ENST00000528961.1	CRYAB	crystallin, alpha B
chr10_+_1102721	0.43	ENST00000263150.4	WDR37	WD repeat domain 37
chr11_+_71938925	0.41	ENST00000538751.1	INPPL1	inositol polyphosphate phosphatase-like 1
chr16_-_53537105	0.41	ENST00000568596.1 ENST00000570004.1 ENST00000564497.1 ENST00000300245.4 ENST00000394657.7	AKTIP	AKT interacting protein
chr11_+_67776012	0.40	ENST00000539229.1	ALDH3B1	aldehyde dehydrogenase 3 family, member B1
chr2_+_201936707	0.40	ENST00000433898.1 ENST00000454214.1	NDUFB3	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr10_+_60028818	0.39	ENST00000333926.5	CISD1	CDGSH iron sulfur domain 1
chr13_+_30002741	0.39	ENST00000380808.2	MTUS2	microtubule associated tumor suppressor candidate 2
chr11_-_73687997	0.39	ENST00000545212.1	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)
chr12_-_71003568	0.39	ENST00000547715.1 ENST00000451516.2 ENST00000538708.1 ENST00000550857.1 ENST00000261266.5	PTPRB	protein tyrosine phosphatase, receptor type, B
chr6_+_32407619	0.39	ENST00000395388.2 ENST00000374982.5	HLA-DRA	major histocompatibility complex, class II, DR alpha
chr12_+_4714145	0.38	ENST00000545342.1	DYRK4	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr3_-_49823941	0.38	ENST00000321599.4 ENST00000395238.1 ENST00000468463.1 ENST00000460540.1	IP6K1	inositol hexakisphosphate kinase 1
chr15_+_75335604	0.38	ENST00000563393.1	PPCDC	phosphopantothenoylcysteine decarboxylase
chr1_-_19811132	0.38	ENST00000433834.1	CAPZB	capping protein (actin filament) muscle Z-line, beta
chr8_+_28174496	0.37	ENST00000518479.1	PNOC	prepronociceptin
chr12_+_62654119	0.37	ENST00000353364.3 ENST00000549523.1 ENST00000280377.5	USP15	ubiquitin specific peptidase 15
chr17_-_7145106	0.37	ENST00000577035.1	GABARAP	GABA(A) receptor-associated protein
chr10_+_70661014	0.37	ENST00000373585.3	DDX50	DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr4_+_52709229	0.37	ENST00000334635.5 ENST00000381441.3 ENST00000381437.4	DCUN1D4	DCN1, defective in cullin neddylation 1, domain containing 4
chr22_-_37882395	0.36	ENST00000416983.3 ENST00000424765.2 ENST00000356998.3	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr8_+_71485681	0.36	ENST00000391684.1	AC120194.1	AC120194.1
chr3_+_50388126	0.36	ENST00000425346.1 ENST00000424512.1 ENST00000232508.5 ENST00000418577.1 ENST00000606589.1	CYB561D2 XXcos-LUCA11.5	cytochrome b561 family, member D2 Uncharacterized protein
chr12_-_88974236	0.36	ENST00000228280.5 ENST00000552044.1 ENST00000357116.4	KITLG	KIT ligand
chr10_-_79398127	0.35	ENST00000372443.1	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr14_-_65569186	0.35	ENST00000555932.1 ENST00000358664.4 ENST00000284165.6 ENST00000358402.4 ENST00000246163.2 ENST00000556979.1 ENST00000555667.1 ENST00000557746.1 ENST00000556443.1	MAX	MYC associated factor X
chr8_-_6420565	0.35	ENST00000338312.6	ANGPT2	angiopoietin 2
chr12_+_59989918	0.34	ENST00000547379.1 ENST00000549465.1	SLC16A7	solute carrier family 16 (monocarboxylate transporter), member 7
chr12_+_108908962	0.34	ENST00000552695.1 ENST00000552758.1 ENST00000361549.2	FICD	FIC domain containing
chr1_-_150979333	0.34	ENST00000312210.5	FAM63A	family with sequence similarity 63, member A
chr19_+_49375649	0.34	ENST00000200453.5	PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr3_-_185641681	0.34	ENST00000259043.7	TRA2B	transformer 2 beta homolog (Drosophila)
chr14_-_64194745	0.33	ENST00000247225.6	SGPP1	sphingosine-1-phosphate phosphatase 1
chr16_-_30134524	0.33	ENST00000395202.1 ENST00000395199.3 ENST00000263025.4 ENST00000322266.5 ENST00000403394.1	MAPK3	mitogen-activated protein kinase 3
chr14_+_24867992	0.33	ENST00000382554.3	NYNRIN	NYN domain and retroviral integrase containing
chr1_-_150978953	0.33	ENST00000493834.2	FAM63A	family with sequence similarity 63, member A
chrX_-_13835147	0.33	ENST00000493677.1 ENST00000355135.2	GPM6B	glycoprotein M6B
chr4_-_175443484	0.32	ENST00000514584.1 ENST00000542498.1 ENST00000296521.7 ENST00000422112.2 ENST00000504433.1	HPGD	hydroxyprostaglandin dehydrogenase 15-(NAD)
chr1_-_11118896	0.31	ENST00000465788.1	SRM	spermidine synthase
chr11_-_6426635	0.30	ENST00000608645.1 ENST00000608394.1 ENST00000529519.1	APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chrX_-_153200676	0.30	ENST00000464845.1	NAA10	N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr11_-_111794446	0.30	ENST00000527950.1	CRYAB	crystallin, alpha B
chr16_-_57219966	0.30	ENST00000565760.1 ENST00000309137.8 ENST00000570184.1 ENST00000562324.1	FAM192A	family with sequence similarity 192, member A
chr9_-_132805430	0.29	ENST00000446176.2 ENST00000355681.3 ENST00000420781.1	FNBP1	formin binding protein 1
chr2_-_71454185	0.29	ENST00000244221.8	PAIP2B	poly(A) binding protein interacting protein 2B
chr13_+_96329381	0.29	ENST00000602402.1 ENST00000376795.6	DNAJC3	DnaJ (Hsp40) homolog, subfamily C, member 3
chr9_+_34990219	0.28	ENST00000541010.1 ENST00000454002.2 ENST00000545841.1	DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5
chrX_+_129473916	0.28	ENST00000545805.1 ENST00000543953.1 ENST00000218197.5	SLC25A14	solute carrier family 25 (mitochondrial carrier, brain), member 14
chr2_+_58134756	0.28	ENST00000435505.2 ENST00000417641.2	VRK2	vaccinia related kinase 2
chr21_-_35987438	0.28	ENST00000313806.4	RCAN1	regulator of calcineurin 1
chr5_-_132113036	0.28	ENST00000378706.1	SEPT8	septin 8
chr6_+_73076432	0.27	ENST00000414192.2	RIMS1	regulating synaptic membrane exocytosis 1
chr12_+_56325812	0.27	ENST00000394147.1 ENST00000551156.1 ENST00000553783.1 ENST00000557080.1 ENST00000432422.3 ENST00000556001.1	DGKA	diacylglycerol kinase, alpha 80kDa
chr8_+_26240414	0.27	ENST00000380629.2	BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	3.5	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	2.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	1.8	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	2.3	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	7.1	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	1.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.4	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.3	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	1.2	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	1.6	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	1.1	PID RAS PATHWAY	Regulation of Ras family activation
0.0	1.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	5.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.2	PID ENDOTHELIN PATHWAY	Endothelins
0.0	1.0	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	1.4	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.7	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.5	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.7	PID MYC PATHWAY	C-MYC pathway
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.8	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.8	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.7	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.5	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.6	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.4	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.5	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.6	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.3	PID HES HEY PATHWAY	Notch-mediated HES/HEY network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	13.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2	2.9	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	1.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	1.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	2.0	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	3.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	3.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.3	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	0.8	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	1.8	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	1.8	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	0.6	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	2.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	3.8	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	1.3	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	1.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	1.3	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.7	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.7	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	1.0	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.5	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	1.8	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	0.3	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.5	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.6	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	1.0	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.5	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	12.1	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
1.2	3.5	GO:0072277	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
1.1	9.8	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
1.0	3.1	GO:1904395	retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.8	1.7	GO:1990523	bone regeneration(GO:1990523)
0.7	2.0	GO:1902568	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.7	2.0	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.6	1.9	GO:0021569	rhombomere 3 development(GO:0021569)
0.5	2.1	GO:0090076	relaxation of skeletal muscle(GO:0090076)
0.5	1.5	GO:0019417	sulfur oxidation(GO:0019417)
0.5	0.5	GO:0043300	regulation of myeloid leukocyte mediated immunity(GO:0002886) regulation of leukocyte degranulation(GO:0043300)
0.5	1.8	GO:0050928	negative regulation of positive chemotaxis(GO:0050928)
0.4	1.3	GO:0099552	trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.4	1.1	GO:0019482	purine nucleobase catabolic process(GO:0006145) beta-alanine metabolic process(GO:0019482)
0.3	2.4	GO:0023021	termination of signal transduction(GO:0023021)
0.3	1.0	GO:1990108	protein linear deubiquitination(GO:1990108)
0.3	1.2	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.3	2.1	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.3	0.9	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.3	1.2	GO:0052330	induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of type B pancreatic cell development(GO:2000078)
0.3	1.4	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3	3.1	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
0.3	0.8	GO:0072019	carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.3	0.8	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.2	1.5	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.2	0.9	GO:1903778	protein localization to vacuolar membrane(GO:1903778)
0.2	0.6	GO:0031394	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2	1.2	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2	0.8	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2	0.6	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.2	0.6	GO:0009912	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.2	2.9	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.2	0.8	GO:0072144	mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.2	1.5	GO:0015727	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.2	0.6	GO:1902748	positive regulation of lens fiber cell differentiation(GO:1902748)
0.2	0.6	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.2	0.5	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.2	0.6	GO:0051866	general adaptation syndrome(GO:0051866)
0.1	1.0	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.1	2.2	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.1	1.0	GO:0051126	negative regulation of actin nucleation(GO:0051126)
0.1	0.4	GO:0033025	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1	2.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	1.1	GO:0045794	negative regulation of cell volume(GO:0045794)
0.1	0.9	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1	0.3	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1	0.8	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1	3.3	GO:0071498	cellular response to fluid shear stress(GO:0071498)
0.1	0.4	GO:0002503	peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1	0.4	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
0.1	3.9	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.1	0.2	GO:0002888	positive regulation of myeloid leukocyte mediated immunity(GO:0002888) positive regulation of leukocyte degranulation(GO:0043302)
0.1	0.3	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.1	0.3	GO:0070541	response to platinum ion(GO:0070541)
0.1	0.3	GO:0006668	sphinganine-1-phosphate metabolic process(GO:0006668)
0.1	0.5	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	0.2	GO:0050902	leukocyte adhesive activation(GO:0050902)
0.1	0.5	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	0.3	GO:0017198	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1	2.8	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	0.3	GO:0000189	MAPK import into nucleus(GO:0000189)
0.1	0.7	GO:0042908	xenobiotic transport(GO:0042908)
0.1	1.6	GO:0015800	acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.1	0.9	GO:0045116	protein neddylation(GO:0045116)
0.1	0.6	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1	0.5	GO:0042262	DNA protection(GO:0042262)
0.0	0.8	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.8	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.7	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.2	GO:0034344	microglial cell activation involved in immune response(GO:0002282) type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.3	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.3	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:2001187	CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0	0.7	GO:0050872	white fat cell differentiation(GO:0050872) cellular response to lithium ion(GO:0071285)
0.0	0.9	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.4	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.5	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.4	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0	0.2	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0	0.2	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	1.2	GO:0003416	endochondral bone growth(GO:0003416)
0.0	0.4	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	1.1	GO:0030318	melanocyte differentiation(GO:0030318)
0.0	0.4	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.1	GO:0010157	response to chlorate(GO:0010157)
0.0	1.6	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.3	GO:2001300	lipoxin metabolic process(GO:2001300)
0.0	1.3	GO:0032456	endocytic recycling(GO:0032456)
0.0	1.2	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.2	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.8	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:1903597	negative regulation of gap junction assembly(GO:1903597)
0.0	0.3	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0010564	regulation of cell cycle process(GO:0010564)
0.0	0.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.6	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.4	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.2	GO:0051610	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0	0.5	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.3	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	1.3	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.0	GO:0043400	cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
0.0	0.1	GO:1903960	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) plasma membrane long-chain fatty acid transport(GO:0015911) negative regulation of anion transmembrane transport(GO:1903960)
0.0	0.8	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.2	GO:0046146	tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.3	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.1	GO:0021842	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0	1.3	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	5.3	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.0	3.5	GO:0015992	proton transport(GO:0015992)
0.0	0.9	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.4	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.4	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.2	GO:0071374	cellular response to parathyroid hormone stimulus(GO:0071374)
0.0	0.2	GO:0032930	positive regulation of superoxide anion generation(GO:0032930)
0.0	0.7	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0	0.1	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.0	0.9	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.4	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.0	1.1	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.2	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
0.0	0.5	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	0.1	GO:0038169	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0	0.2	GO:0044342	type B pancreatic cell proliferation(GO:0044342)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.4	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.0	0.2	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.1	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.3	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.2	GO:0045475	locomotor rhythm(GO:0045475)
0.0	0.1	GO:0023019	signal transduction involved in regulation of gene expression(GO:0023019)
0.0	0.6	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.2	GO:0001502	cartilage condensation(GO:0001502)
0.0	2.4	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	0.4	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.2	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.4	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	7.4	GO:0050436	microfibril binding(GO:0050436)
1.2	3.5	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
1.1	4.3	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.9	12.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.8	3.1	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.5	2.0	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.5	2.9	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3	2.5	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
0.3	1.4	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.3	3.7	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3	0.8	GO:0035379	carbon dioxide transmembrane transporter activity(GO:0035379)
0.3	0.8	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.2	2.4	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.2	1.3	GO:0015057	thrombin receptor activity(GO:0015057)
0.2	1.5	GO:0001515	opioid peptide activity(GO:0001515)
0.2	0.8	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2	1.1	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.2	0.8	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.2	1.1	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.2	0.9	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.2	1.8	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.1	4.6	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	0.7	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.1	1.6	GO:0004017	adenylate kinase activity(GO:0004017)
0.1	1.2	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.1	2.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1	0.5	GO:0030613	oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.1	0.3	GO:0004766	spermidine synthase activity(GO:0004766)
0.1	0.8	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	0.5	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	0.4	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.5	GO:0019776	Atg8 ligase activity(GO:0019776)
0.1	0.5	GO:0004331	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1	0.7	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.1	1.1	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.1	0.3	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1	0.9	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.1	0.7	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.1	2.1	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	0.3	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1	0.2	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1	0.5	GO:0061133	endopeptidase activator activity(GO:0061133)
0.1	1.8	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	0.5	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.1	0.4	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1	1.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	1.5	GO:0031489	myosin V binding(GO:0031489)
0.1	0.4	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.1	1.5	GO:0071949	FAD binding(GO:0071949)
0.0	0.3	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	1.4	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.2	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.3	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	1.2	GO:0015248	sterol transporter activity(GO:0015248)
0.0	2.0	GO:0070888	E-box binding(GO:0070888)
0.0	1.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.2	GO:0033265	choline binding(GO:0033265)
0.0	1.3	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.8	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.4	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	3.4	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.6	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.6	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.0	2.4	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	0.2	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.4	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.2	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.6	GO:0005112	Notch binding(GO:0005112)
0.0	1.2	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	1.2	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.6	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.4	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.4	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	2.7	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.1	GO:0008240	tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.4	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.3	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.3	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.6	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.3	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.3	GO:0004707	MAP kinase activity(GO:0004707)
0.0	1.1	GO:0019905	syntaxin binding(GO:0019905)
0.0	0.3	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.4	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.2	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	2.9	GO:0019887	protein kinase regulator activity(GO:0019887)
0.0	0.3	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.1	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.0	0.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.5	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.2	GO:0016805	dipeptidase activity(GO:0016805)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	9.8	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.4	2.1	GO:0001652	granular component(GO:0001652)
0.3	2.4	GO:0016012	sarcoglycan complex(GO:0016012)
0.3	0.8	GO:0020003	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.3	0.8	GO:0005588	collagen type V trimer(GO:0005588)
0.3	2.0	GO:0000322	storage vacuole(GO:0000322)
0.2	0.9	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2	0.8	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.2	0.5	GO:0043224	nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1	2.1	GO:0097512	cardiac myofibril(GO:0097512)
0.1	1.5	GO:0033093	Weibel-Palade body(GO:0033093)
0.1	1.9	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1	2.2	GO:0042599	lamellar body(GO:0042599)
0.1	0.4	GO:0070695	FHF complex(GO:0070695)
0.1	0.3	GO:1990761	growth cone lamellipodium(GO:1990761)
0.1	0.6	GO:0032280	symmetric synapse(GO:0032280)
0.1	0.7	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.1	1.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.8	GO:0005955	calcineurin complex(GO:0005955)
0.1	3.2	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.1	0.5	GO:0008537	proteasome activator complex(GO:0008537)
0.1	7.1	GO:0031594	neuromuscular junction(GO:0031594)
0.1	0.4	GO:0070545	PeBoW complex(GO:0070545)
0.1	0.4	GO:0071203	WASH complex(GO:0071203)
0.0	0.5	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.6	GO:0030478	actin cap(GO:0030478)
0.0	1.9	GO:0097542	ciliary tip(GO:0097542)
0.0	0.3	GO:0031415	NatA complex(GO:0031415)
0.0	0.6	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.2	GO:0016589	NURF complex(GO:0016589)
0.0	2.9	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	3.0	GO:0005902	microvillus(GO:0005902)
0.0	0.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.2	GO:0001740	Barr body(GO:0001740)
0.0	11.0	GO:0019898	extrinsic component of membrane(GO:0019898)
0.0	4.2	GO:0008021	synaptic vesicle(GO:0008021)
0.0	1.8	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	2.5	GO:0005746	mitochondrial respiratory chain(GO:0005746)
0.0	1.9	GO:0005811	lipid particle(GO:0005811)
0.0	0.2	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.2	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	2.3	GO:0044853	plasma membrane raft(GO:0044853)
0.0	2.3	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	2.0	GO:0030175	filopodium(GO:0030175)
0.0	0.8	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	4.1	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.3	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.2	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.4	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.2	GO:0005833	hemoglobin complex(GO:0005833)
0.0	1.0	GO:0016324	apical plasma membrane(GO:0016324)
0.0	1.0	GO:0043204	perikaryon(GO:0043204)
0.0	4.0	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	1.1	GO:0000502	proteasome complex(GO:0000502)
0.0	0.4	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.6	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.8	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	0.2	GO:0036020	endolysosome membrane(GO:0036020)
0.0	0.6	GO:0005881	cytoplasmic microtubule(GO:0005881)