ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
THRA Links Ensembl NCBI GeneCards UniProt	ENSG00000126351.8	THRA
RXRB Links Ensembl NCBI GeneCards UniProt	ENSG00000204231.6	RXRB

Gene	Promoter	Pearson corr. coef.	P-value	Plot
THRA	hg19_v2_chr17_+_38219063_38219154	-0.55	2.6e-02	Click!
RXRB	hg19_v2_chr6_-_33168391_33168465	0.03	9.1e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr22_+_23264766	9.00	ENST00000390331.2	IGLC7	immunoglobulin lambda constant 7
chr14_-_106054659	8.42	ENST00000390539.2	IGHA2	immunoglobulin heavy constant alpha 2 (A2m marker)
chr22_+_23134974	6.99	ENST00000390314.2	IGLV2-11	immunoglobulin lambda variable 2-11
chr22_+_23165153	5.96	ENST00000390317.2	IGLV2-8	immunoglobulin lambda variable 2-8
chr16_+_85942594	5.33	ENST00000566369.1	IRF8	interferon regulatory factor 8
chr19_-_39826639	4.82	ENST00000602185.1 ENST00000598034.1 ENST00000601387.1 ENST00000595636.1 ENST00000253054.8 ENST00000594700.1 ENST00000597595.1	GMFG	glia maturation factor, gamma
chr22_+_23077065	4.59	ENST00000390310.2	IGLV2-18	immunoglobulin lambda variable 2-18
chr14_-_55369525	4.30	ENST00000543643.2 ENST00000536224.2 ENST00000395514.1 ENST00000491895.2	GCH1	GTP cyclohydrolase 1
chr14_-_106174960	4.27	ENST00000390547.2	IGHA1	immunoglobulin heavy constant alpha 1
chr22_+_23040274	4.27	ENST00000390306.2	IGLV2-23	immunoglobulin lambda variable 2-23
chr22_+_23243156	3.92	ENST00000390323.2	IGLC2	immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr6_+_13272904	3.67	ENST00000379335.3 ENST00000379329.1	PHACTR1	phosphatase and actin regulator 1
chr19_-_10450328	2.88	ENST00000160262.5	ICAM3	intercellular adhesion molecule 3
chr19_-_10450287	2.71	ENST00000589261.1 ENST00000590569.1 ENST00000589580.1 ENST00000589249.1	ICAM3	intercellular adhesion molecule 3
chr16_+_85646763	2.47	ENST00000411612.1 ENST00000253458.7	GSE1	Gse1 coiled-coil protein
chr13_-_46756351	2.46	ENST00000323076.2	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr22_+_22764088	2.05	ENST00000390299.2	IGLV1-40	immunoglobulin lambda variable 1-40
chr19_+_6739662	1.80	ENST00000313285.8 ENST00000313244.9 ENST00000596758.1	TRIP10	thyroid hormone receptor interactor 10
chr22_+_22681656	1.78	ENST00000390291.2	IGLV1-50	immunoglobulin lambda variable 1-50 (non-functional)
chr6_-_34664612	1.71	ENST00000374023.3 ENST00000374026.3	C6orf106	chromosome 6 open reading frame 106
chr19_+_49838653	1.64	ENST00000598095.1 ENST00000426897.2 ENST00000323906.4 ENST00000535669.2 ENST00000597602.1 ENST00000595660.1	CD37	CD37 molecule
chr5_+_172332220	1.60	ENST00000518247.1 ENST00000326654.2	ERGIC1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr22_+_22712087	1.60	ENST00000390294.2	IGLV1-47	immunoglobulin lambda variable 1-47
chr11_+_7618413	1.54	ENST00000528883.1	PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr6_-_89673280	1.44	ENST00000369475.3 ENST00000369485.4 ENST00000538899.1 ENST00000265607.6	RNGTT	RNA guanylyltransferase and 5'-phosphatase
chr12_+_7023491	1.40	ENST00000541477.1 ENST00000229277.1	ENO2	enolase 2 (gamma, neuronal)
chr5_+_162887556	1.38	ENST00000393915.4 ENST00000432118.2 ENST00000358715.3	HMMR	hyaluronan-mediated motility receptor (RHAMM)
chr22_-_29138386	1.37	ENST00000544772.1	CHEK2	checkpoint kinase 2
chr3_+_14989186	1.29	ENST00000435454.1 ENST00000323373.6	NR2C2	nuclear receptor subfamily 2, group C, member 2
chr12_+_7023735	1.27	ENST00000538763.1 ENST00000544774.1 ENST00000545045.2	ENO2	enolase 2 (gamma, neuronal)
chr6_+_64346386	1.25	ENST00000509330.1	PHF3	PHD finger protein 3
chr15_-_80215984	1.24	ENST00000485386.1 ENST00000479961.1	ST20 ST20-MTHFS	suppressor of tumorigenicity 20 ST20-MTHFS readthrough
chr20_+_57430162	1.21	ENST00000450130.1 ENST00000349036.3 ENST00000423897.1	GNAS	GNAS complex locus
chr11_+_7534999	1.14	ENST00000528947.1 ENST00000299492.4	PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_-_151431647	1.13	ENST00000368863.2 ENST00000409503.1 ENST00000491586.1 ENST00000533351.1 ENST00000540984.1	POGZ	pogo transposable element with ZNF domain
chr12_+_102513950	1.11	ENST00000378128.3 ENST00000327680.2 ENST00000541394.1 ENST00000543784.1	PARPBP	PARP1 binding protein
chr16_+_85646891	1.09	ENST00000393243.1	GSE1	Gse1 coiled-coil protein
chrX_-_129299638	1.08	ENST00000535724.1 ENST00000346424.2	AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1
chr2_+_74757050	1.03	ENST00000352222.3 ENST00000437202.1	HTRA2	HtrA serine peptidase 2
chr8_+_110552831	0.98	ENST00000530629.1	EBAG9	estrogen receptor binding site associated, antigen, 9
chr13_-_41635512	0.98	ENST00000405737.2	ELF1	E74-like factor 1 (ets domain transcription factor)
chr1_+_45212074	0.96	ENST00000372217.1	KIF2C	kinesin family member 2C
chr2_-_176046391	0.96	ENST00000392541.3 ENST00000409194.1	ATP5G3	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr15_-_34629922	0.96	ENST00000559484.1 ENST00000354181.3 ENST00000558589.1 ENST00000458406.2	SLC12A6	solute carrier family 12 (potassium/chloride transporter), member 6
chr1_+_45212051	0.94	ENST00000372222.3	KIF2C	kinesin family member 2C
chr22_-_21581926	0.94	ENST00000401924.1	GGT2	gamma-glutamyltransferase 2
chr1_+_70876891	0.92	ENST00000411986.2	CTH	cystathionase (cystathionine gamma-lyase)
chr12_+_102514019	0.89	ENST00000537257.1 ENST00000358383.5 ENST00000392911.2	PARPBP	PARP1 binding protein
chr6_-_99797522	0.88	ENST00000389677.5	FAXC	failed axon connections homolog (Drosophila)
chr22_-_29137771	0.87	ENST00000439200.1 ENST00000405598.1 ENST00000398017.2 ENST00000425190.2 ENST00000348295.3 ENST00000382578.1 ENST00000382565.1 ENST00000382566.1 ENST00000382580.2 ENST00000328354.6	CHEK2	checkpoint kinase 2
chr10_+_11207438	0.86	ENST00000609692.1 ENST00000354897.3	CELF2	CUGBP, Elav-like family member 2
chr1_-_151431909	0.86	ENST00000361398.3 ENST00000271715.2	POGZ	pogo transposable element with ZNF domain
chr11_-_58343319	0.84	ENST00000395074.2	LPXN	leupaxin
chr2_-_183387283	0.80	ENST00000435564.1	PDE1A	phosphodiesterase 1A, calmodulin-dependent
chrX_-_132887729	0.80	ENST00000406757.2	GPC3	glypican 3
chr19_+_1065922	0.78	ENST00000539243.2	HMHA1	histocompatibility (minor) HA-1
chr19_+_54371114	0.77	ENST00000448420.1 ENST00000439000.1 ENST00000391770.4 ENST00000391771.1	MYADM	myeloid-associated differentiation marker
chr1_+_70876926	0.77	ENST00000370938.3 ENST00000346806.2	CTH	cystathionase (cystathionine gamma-lyase)
chr17_+_27071002	0.73	ENST00000262395.5 ENST00000422344.1 ENST00000444415.3 ENST00000262396.6	TRAF4	TNF receptor-associated factor 4
chr10_+_76586348	0.73	ENST00000372724.1 ENST00000287239.4 ENST00000372714.1	KAT6B	K(lysine) acetyltransferase 6B
chr11_-_77122928	0.72	ENST00000528203.1 ENST00000528592.1 ENST00000528633.1 ENST00000529248.1	PAK1	p21 protein (Cdc42/Rac)-activated kinase 1
chr22_+_17082732	0.72	ENST00000558085.2 ENST00000592918.1 ENST00000400593.2 ENST00000592107.1 ENST00000426585.1 ENST00000591299.1	TPTEP1	transmembrane phosphatase with tensin homology pseudogene 1
chr1_+_203274639	0.71	ENST00000290551.4	BTG2	BTG family, member 2
chr11_-_77123065	0.69	ENST00000530617.1	PAK1	p21 protein (Cdc42/Rac)-activated kinase 1
chr17_+_34171081	0.68	ENST00000585577.1	TAF15	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr3_-_195270162	0.67	ENST00000438848.1 ENST00000328432.3	PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2
chr13_-_95131923	0.66	ENST00000377028.5 ENST00000446125.1	DCT	dopachrome tautomerase
chr2_-_68479614	0.66	ENST00000234310.3	PPP3R1	protein phosphatase 3, regulatory subunit B, alpha
chr14_-_24036943	0.65	ENST00000556843.1 ENST00000397120.3 ENST00000557189.1	AP1G2	adaptor-related protein complex 1, gamma 2 subunit
chr15_-_34630234	0.62	ENST00000558667.1 ENST00000561120.1 ENST00000559236.1 ENST00000397702.2	SLC12A6	solute carrier family 12 (potassium/chloride transporter), member 6
chr10_+_11784360	0.61	ENST00000379215.4 ENST00000420401.1	ECHDC3	enoyl CoA hydratase domain containing 3
chr3_-_98241760	0.60	ENST00000507874.1 ENST00000502299.1 ENST00000508659.1 ENST00000510545.1 ENST00000511667.1 ENST00000394185.2 ENST00000394181.2 ENST00000508902.1 ENST00000341181.6 ENST00000437922.1 ENST00000394180.2	CLDND1	claudin domain containing 1
chr2_-_183387064	0.59	ENST00000536095.1 ENST00000331935.6 ENST00000358139.2 ENST00000456212.1	PDE1A	phosphodiesterase 1A, calmodulin-dependent
chr11_-_59578202	0.58	ENST00000300151.4	MRPL16	mitochondrial ribosomal protein L16
chr11_+_117049854	0.58	ENST00000278951.7	SIDT2	SID1 transmembrane family, member 2
chrX_+_9431324	0.58	ENST00000407597.2 ENST00000424279.1 ENST00000536365.1 ENST00000441088.1 ENST00000380961.1 ENST00000415293.1	TBL1X	transducin (beta)-like 1X-linked
chr1_+_93544821	0.57	ENST00000370303.4	MTF2	metal response element binding transcription factor 2
chr2_+_86426478	0.55	ENST00000254644.8 ENST00000605125.1 ENST00000337109.4 ENST00000409180.1	MRPL35	mitochondrial ribosomal protein L35
chr10_+_26986582	0.53	ENST00000376215.5 ENST00000376203.5	PDSS1	prenyl (decaprenyl) diphosphate synthase, subunit 1
chr1_+_93544791	0.53	ENST00000545708.1 ENST00000540243.1 ENST00000370298.4	MTF2	metal response element binding transcription factor 2
chr17_-_9940058	0.53	ENST00000585266.1	GAS7	growth arrest-specific 7
chr1_+_41204506	0.52	ENST00000525290.1 ENST00000530965.1 ENST00000416859.2 ENST00000308733.5	NFYC	nuclear transcription factor Y, gamma
chr10_-_52645379	0.52	ENST00000395489.2	A1CF	APOBEC1 complementation factor
chr3_-_15374659	0.51	ENST00000426925.1	SH3BP5	SH3-domain binding protein 5 (BTK-associated)
chr2_-_192016316	0.50	ENST00000358470.4 ENST00000432798.1 ENST00000450994.1	STAT4	signal transducer and activator of transcription 4
chr12_+_56477093	0.50	ENST00000549672.1 ENST00000415288.2	ERBB3	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr1_-_85040090	0.49	ENST00000370630.5	CTBS	chitobiase, di-N-acetyl-
chr12_-_122018859	0.49	ENST00000536437.1 ENST00000377071.4 ENST00000538046.2	KDM2B	lysine (K)-specific demethylase 2B
chrX_-_39956656	0.49	ENST00000397354.3 ENST00000378444.4	BCOR	BCL6 corepressor
chr10_+_81107271	0.48	ENST00000448165.1	PPIF	peptidylprolyl isomerase F
chr10_-_52645416	0.48	ENST00000374001.2 ENST00000373997.3 ENST00000373995.3 ENST00000282641.2 ENST00000395495.1 ENST00000414883.1	A1CF	APOBEC1 complementation factor
chr2_-_179315786	0.47	ENST00000457633.1 ENST00000438687.3 ENST00000325748.4	PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator
chr15_-_75230368	0.47	ENST00000564811.1 ENST00000562233.1 ENST00000567270.1 ENST00000568783.1	COX5A	cytochrome c oxidase subunit Va
chr1_-_173886491	0.46	ENST00000367698.3	SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1
chr16_+_3074002	0.46	ENST00000326266.8 ENST00000574549.1 ENST00000575576.1 ENST00000253952.9	THOC6	THO complex 6 homolog (Drosophila)
chr11_+_111896320	0.45	ENST00000531306.1 ENST00000537636.1	DLAT	dihydrolipoamide S-acetyltransferase
chr11_-_118661828	0.45	ENST00000264018.4	DDX6	DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr2_-_230786619	0.44	ENST00000389045.3 ENST00000409677.1	TRIP12	thyroid hormone receptor interactor 12
chr10_+_80828774	0.43	ENST00000334512.5	ZMIZ1	zinc finger, MIZ-type containing 1
chr17_+_27369918	0.43	ENST00000323372.4	PIPOX	pipecolic acid oxidase
chr2_+_55459495	0.42	ENST00000272317.6 ENST00000449323.1	RPS27A	ribosomal protein S27a
chr14_-_102552659	0.42	ENST00000441629.2	HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1
chr17_+_46184911	0.41	ENST00000580219.1 ENST00000452859.2 ENST00000393405.2 ENST00000439357.2 ENST00000359238.2	SNX11	sorting nexin 11
chr11_+_3876859	0.40	ENST00000300737.4	STIM1	stromal interaction molecule 1
chr2_+_90153696	0.40	ENST00000417279.2	IGKV3D-15	immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr12_-_51566562	0.40	ENST00000548108.1	TFCP2	transcription factor CP2
chr18_+_268148	0.39	ENST00000581677.1	RP11-705O1.8	RP11-705O1.8
chr5_+_71014990	0.38	ENST00000296777.4	CARTPT	CART prepropeptide
chr19_+_16771936	0.38	ENST00000187762.2 ENST00000599479.1	TMEM38A	transmembrane protein 38A
chr22_-_24316648	0.38	ENST00000403754.3 ENST00000430101.2 ENST00000398344.4	DDT	D-dopachrome tautomerase
chr4_+_26322409	0.37	ENST00000514807.1 ENST00000348160.4 ENST00000509158.1 ENST00000355476.3	RBPJ	recombination signal binding protein for immunoglobulin kappa J region
chr3_-_187009798	0.37	ENST00000337774.5	MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr2_-_179315490	0.37	ENST00000487082.1	PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator
chr17_+_37894570	0.37	ENST00000394211.3	GRB7	growth factor receptor-bound protein 7
chr10_-_104178857	0.36	ENST00000020673.5	PSD	pleckstrin and Sec7 domain containing
chr11_-_17565854	0.36	ENST00000005226.7	USH1C	Usher syndrome 1C (autosomal recessive, severe)
chr1_+_236558694	0.35	ENST00000359362.5	EDARADD	EDAR-associated death domain
chr17_+_6899366	0.35	ENST00000251535.6	ALOX12	arachidonate 12-lipoxygenase
chr1_-_11907829	0.35	ENST00000376480.3	NPPA	natriuretic peptide A
chr9_-_114246635	0.35	ENST00000338205.5	KIAA0368	KIAA0368
chr4_-_151936416	0.34	ENST00000510413.1 ENST00000507224.1	LRBA	LPS-responsive vesicle trafficking, beach and anchor containing
chr12_-_102513843	0.34	ENST00000551744.2 ENST00000552283.1	NUP37	nucleoporin 37kDa
chr11_+_111896090	0.34	ENST00000393051.1	DLAT	dihydrolipoamide S-acetyltransferase
chr11_+_64879317	0.33	ENST00000526809.1 ENST00000279263.7 ENST00000524986.1 ENST00000534371.1 ENST00000540748.1 ENST00000525385.1 ENST00000345348.5 ENST00000531321.1 ENST00000529414.1 ENST00000526085.1 ENST00000530750.1	TM7SF2	transmembrane 7 superfamily member 2
chr4_+_26322185	0.32	ENST00000361572.6	RBPJ	recombination signal binding protein for immunoglobulin kappa J region
chr22_-_29784519	0.32	ENST00000357586.2 ENST00000356015.2 ENST00000432560.2 ENST00000317368.7	AP1B1	adaptor-related protein complex 1, beta 1 subunit
chr2_-_179315453	0.31	ENST00000432031.2	PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator
chr5_-_149829294	0.31	ENST00000401695.3	RPS14	ribosomal protein S14
chr2_+_87565634	0.31	ENST00000421835.2	IGKV3OR2-268	immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr12_-_51566592	0.30	ENST00000257915.5 ENST00000548115.1	TFCP2	transcription factor CP2
chr14_+_76618242	0.30	ENST00000557542.1 ENST00000557263.1 ENST00000557207.1 ENST00000312858.5 ENST00000261530.7	GPATCH2L	G patch domain containing 2-like
chr11_-_119599794	0.30	ENST00000264025.3	PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr16_-_47007545	0.30	ENST00000317089.5	DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2
chr5_-_149829314	0.30	ENST00000407193.1	RPS14	ribosomal protein S14
chr17_-_7082668	0.29	ENST00000573083.1 ENST00000574388.1	ASGR1	asialoglycoprotein receptor 1
chr14_-_58893832	0.28	ENST00000556007.2	TIMM9	translocase of inner mitochondrial membrane 9 homolog (yeast)
chr17_-_39222131	0.28	ENST00000394015.2	KRTAP2-4	keratin associated protein 2-4
chr1_-_6453399	0.28	ENST00000608083.1	ACOT7	acyl-CoA thioesterase 7
chrX_+_152990302	0.27	ENST00000218104.3	ABCD1	ATP-binding cassette, sub-family D (ALD), member 1
chr2_-_90538397	0.27	ENST00000443397.3	RP11-685N3.1	Uncharacterized protein
chr17_-_41132410	0.27	ENST00000409446.3 ENST00000453594.1 ENST00000409399.1 ENST00000421990.2	PTGES3L PTGES3L-AARSD1	prostaglandin E synthase 3 (cytosolic)-like PTGES3L-AARSD1 readthrough
chr13_-_28545276	0.27	ENST00000381020.7	CDX2	caudal type homeobox 2
chr3_-_197024965	0.27	ENST00000392382.2	DLG1	discs, large homolog 1 (Drosophila)
chr11_-_30607819	0.26	ENST00000448418.2	MPPED2	metallophosphoesterase domain containing 2
chr2_-_65593784	0.26	ENST00000443619.2	SPRED2	sprouty-related, EVH1 domain containing 2
chr3_+_25831567	0.26	ENST00000280701.3 ENST00000420173.2	OXSM	3-oxoacyl-ACP synthase, mitochondrial
chr22_+_30163340	0.26	ENST00000330029.6 ENST00000401406.3	UQCR10	ubiquinol-cytochrome c reductase, complex III subunit X
chr19_+_35629702	0.26	ENST00000351325.4	FXYD1	FXYD domain containing ion transport regulator 1
chr7_+_5085452	0.25	ENST00000353796.3 ENST00000396912.1 ENST00000396904.2	RBAK RBAK-RBAKDN	RB-associated KRAB zinc finger RBAK-RBAKDN readthrough
chr17_+_37894179	0.25	ENST00000577695.1 ENST00000309156.4 ENST00000309185.3	GRB7	growth factor receptor-bound protein 7
chr3_-_187009646	0.25	ENST00000296280.6 ENST00000392470.2 ENST00000169293.6 ENST00000439271.1 ENST00000392472.2 ENST00000392475.2	MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr9_+_131452239	0.24	ENST00000372688.4 ENST00000372686.5	SET	SET nuclear oncogene
chr3_+_9404526	0.24	ENST00000452837.2 ENST00000417036.1 ENST00000419437.1 ENST00000345094.3 ENST00000515662.2	THUMPD3	THUMP domain containing 3
chr11_+_122709200	0.23	ENST00000227348.4	CRTAM	cytotoxic and regulatory T cell molecule
chr20_+_57875658	0.23	ENST00000371025.3	EDN3	endothelin 3
chr11_-_35440796	0.23	ENST00000278379.3	SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr17_-_41132010	0.23	ENST00000409103.1 ENST00000360221.4	PTGES3L-AARSD1	PTGES3L-AARSD1 readthrough
chr12_-_51566849	0.23	ENST00000549867.1 ENST00000307660.4	TFCP2	transcription factor CP2
chr14_-_24616426	0.23	ENST00000216802.5	PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr19_-_40228657	0.22	ENST00000221804.4	CLC	Charcot-Leyden crystal galectin
chr15_-_83316254	0.22	ENST00000567678.1 ENST00000450751.2	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr18_+_61144160	0.22	ENST00000489441.1 ENST00000424602.1	SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr19_+_41117770	0.22	ENST00000601032.1	LTBP4	latent transforming growth factor beta binding protein 4
chr11_-_30608413	0.22	ENST00000528686.1	MPPED2	metallophosphoesterase domain containing 2
chr18_+_12948000	0.22	ENST00000585730.1 ENST00000399892.2 ENST00000589446.1 ENST00000587761.1	SEH1L	SEH1-like (S. cerevisiae)
chr9_+_139305102	0.21	ENST00000371720.1 ENST00000371717.3 ENST00000399219.3	PMPCA	peptidase (mitochondrial processing) alpha
chr3_-_48471454	0.21	ENST00000296440.6 ENST00000448774.2	PLXNB1	plexin B1
chr17_+_48046538	0.21	ENST00000240306.3	DLX4	distal-less homeobox 4
chr7_+_94536898	0.21	ENST00000433360.1 ENST00000340694.4 ENST00000424654.1	PPP1R9A	protein phosphatase 1, regulatory subunit 9A
chr19_-_4066890	0.20	ENST00000322357.4	ZBTB7A	zinc finger and BTB domain containing 7A
chr17_+_8191815	0.20	ENST00000226105.6 ENST00000407006.4 ENST00000580434.1 ENST00000439238.3	RANGRF	RAN guanine nucleotide release factor
chr7_-_140179276	0.20	ENST00000443720.2 ENST00000255977.2	MKRN1	makorin ring finger protein 1
chr12_+_6930964	0.20	ENST00000382315.3	GPR162	G protein-coupled receptor 162
chr1_+_16010779	0.20	ENST00000375799.3 ENST00000375793.2	PLEKHM2	pleckstrin homology domain containing, family M (with RUN domain) member 2
chr3_-_127872625	0.19	ENST00000464873.1	RUVBL1	RuvB-like AAA ATPase 1
chr5_+_139927213	0.19	ENST00000310331.2	EIF4EBP3	eukaryotic translation initiation factor 4E binding protein 3
chr5_-_180666570	0.18	ENST00000509535.1	GNB2L1	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr1_-_109940550	0.18	ENST00000256637.6	SORT1	sortilin 1
chr11_-_3862206	0.17	ENST00000351018.4	RHOG	ras homolog family member G
chr11_-_62752162	0.17	ENST00000458333.2 ENST00000421062.2	SLC22A6	solute carrier family 22 (organic anion transporter), member 6
chr20_+_47538357	0.17	ENST00000371917.4	ARFGEF2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr9_+_117350009	0.17	ENST00000374050.3	ATP6V1G1	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr1_-_6453426	0.17	ENST00000545482.1	ACOT7	acyl-CoA thioesterase 7
chr2_-_49381572	0.16	ENST00000454032.1 ENST00000304421.4	FSHR	follicle stimulating hormone receptor
chr20_+_57875758	0.16	ENST00000395654.3	EDN3	endothelin 3
chr4_+_26321284	0.16	ENST00000506956.1 ENST00000512671.1 ENST00000345843.3 ENST00000342295.1	RBPJ	recombination signal binding protein for immunoglobulin kappa J region
chr14_+_81421861	0.16	ENST00000298171.2	TSHR	thyroid stimulating hormone receptor
chr14_-_31889782	0.15	ENST00000543095.2	HEATR5A	HEAT repeat containing 5A
chr6_-_31782813	0.15	ENST00000375654.4	HSPA1L	heat shock 70kDa protein 1-like
chr11_-_83393457	0.15	ENST00000404783.3	DLG2	discs, large homolog 2 (Drosophila)
chr14_+_22963806	0.15	ENST00000390493.1	TRAJ44	T cell receptor alpha joining 44
chr1_-_2145620	0.15	ENST00000545087.1	AL590822.1	Uncharacterized protein
chr12_+_6930703	0.15	ENST00000311268.3	GPR162	G protein-coupled receptor 162
chr6_-_31745085	0.14	ENST00000375686.3 ENST00000447450.1	VWA7	von Willebrand factor A domain containing 7
chr12_+_6930813	0.14	ENST00000428545.2	GPR162	G protein-coupled receptor 162
chr6_-_31745037	0.14	ENST00000375688.4	VWA7	von Willebrand factor A domain containing 7
chr16_+_2076869	0.14	ENST00000424542.2 ENST00000432365.2	SLC9A3R2	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr11_+_65190245	0.13	ENST00000499732.1 ENST00000501122.2 ENST00000601801.1	NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)
chrX_+_101380642	0.13	ENST00000372780.1 ENST00000329035.2	TCEAL2	transcription elongation factor A (SII)-like 2
chr3_-_49058479	0.13	ENST00000440857.1	DALRD3	DALR anticodon binding domain containing 3

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	4.3	GO:0051066	dihydrobiopterin metabolic process(GO:0051066)
1.3	12.7	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.7	2.2	GO:1903926	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.7	4.8	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.4	1.7	GO:0018352	protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.3	1.0	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.3	1.6	GO:0042539	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.3	0.8	GO:1901297	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.3	5.3	GO:0044130	negative regulation of growth of symbiont in host(GO:0044130)
0.2	2.0	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2	1.4	GO:0098501	polynucleotide dephosphorylation(GO:0098501)
0.2	1.4	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.2	29.6	GO:0006958	complement activation, classical pathway(GO:0006958)
0.2	0.8	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.2	0.8	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.2	1.9	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2	1.1	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.2	1.2	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.2	1.0	GO:0016554	cytidine to uridine editing(GO:0016554)
0.2	0.5	GO:0021592	midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.2	0.5	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.2	0.5	GO:2000276	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.2	1.1	GO:1904044	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
0.2	2.0	GO:0051382	kinetochore assembly(GO:0051382)
0.1	0.4	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1	0.4	GO:0019474	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1	0.7	GO:0051792	medium-chain fatty acid biosynthetic process(GO:0051792)
0.1	0.4	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.5	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.1	0.4	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
0.1	2.5	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.1	0.4	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.1	0.4	GO:2001303	lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.1	0.3	GO:0097254	renal tubular secretion(GO:0097254)
0.1	0.4	GO:0043335	protein unfolding(GO:0043335)
0.1	0.8	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1	1.2	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.1	0.7	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.1	1.2	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.1	0.3	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1	0.3	GO:1905229	cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.1	0.3	GO:0001545	primary ovarian follicle growth(GO:0001545)
0.1	0.4	GO:0007296	vitellogenesis(GO:0007296)
0.1	1.2	GO:0046069	cGMP catabolic process(GO:0046069)
0.1	0.2	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1	0.6	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	0.3	GO:0015910	peroxisomal long-chain fatty acid import(GO:0015910)
0.1	0.3	GO:0014807	regulation of somitogenesis(GO:0014807)
0.1	0.9	GO:1901748	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1	0.7	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.1	0.2	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
0.1	0.3	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.1	2.7	GO:0006735	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1	0.5	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.1	0.6	GO:0033227	dsRNA transport(GO:0033227)
0.1	0.2	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1	0.3	GO:0010731	protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1	0.4	GO:1900045	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.2	GO:1903527	positive regulation of membrane tubulation(GO:1903527)
0.0	0.3	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.5	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.4	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	1.2	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.0	0.7	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	6.8	GO:0002377	immunoglobulin production(GO:0002377)
0.0	0.8	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0	0.1	GO:0090034	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0	0.2	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0	1.0	GO:0050860	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.1	GO:1900114	positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.0	0.2	GO:0036414	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0	0.6	GO:0034063	stress granule assembly(GO:0034063)
0.0	6.2	GO:0002223	stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0	0.2	GO:0002420	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.3	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.3	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	1.0	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.5	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.2	GO:0002870	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0	0.2	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0	1.2	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.5	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:1901252	regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253)
0.0	0.5	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.9	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.4	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.1	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	3.1	GO:0043149	contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0	0.1	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.3	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	0.2	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:0060018	astrocyte fate commitment(GO:0060018)
0.0	0.1	GO:1902613	regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0	0.2	GO:0035067	negative regulation of histone acetylation(GO:0035067)
0.0	0.6	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.2	GO:0000492	box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0001826	inner cell mass cell differentiation(GO:0001826)
0.0	0.9	GO:0070125	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0	3.8	GO:0002250	adaptive immune response(GO:0002250)
0.0	0.1	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.0	0.4	GO:0042438	melanin biosynthetic process(GO:0042438)
0.0	0.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.7	GO:0043966	histone H3 acetylation(GO:0043966)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	5.3	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.1	1.5	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	1.8	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	1.3	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	1.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	2.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	1.9	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.9	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	2.0	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	1.2	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	3.7	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.6	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.6	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.8	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	1.2	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.6	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.3	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.4	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.3	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.7	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	2.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.4	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	1.9	REACTOME KINESINS	Genes involved in Kinesins
0.1	0.8	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	5.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	5.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	2.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.4	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	1.2	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	1.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.5	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.6	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.4	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	1.4	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	1.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.7	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.3	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.6	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.2	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.2	12.7	GO:0071748	IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.4	2.7	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.3	1.0	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.2	4.3	GO:0001891	phagocytic cup(GO:0001891)
0.2	0.8	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2	9.0	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.2	0.8	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	0.7	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.1	1.2	GO:0070578	RISC-loading complex(GO:0070578)
0.1	0.7	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1	0.5	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1	0.4	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1	0.7	GO:0005955	calcineurin complex(GO:0005955)
0.1	0.3	GO:0042721	mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1	0.9	GO:0035631	CD40 receptor complex(GO:0035631)
0.1	0.4	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.1	0.2	GO:0005879	axonemal microtubule(GO:0005879)
0.1	1.8	GO:0035371	microtubule plus-end(GO:0035371)
0.1	1.0	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.5	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	1.4	GO:0071437	invadopodium(GO:0071437)
0.0	1.0	GO:0031519	PcG protein complex(GO:0031519)
0.0	1.7	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	1.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.7	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.7	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.2	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.6	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.5	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0	0.4	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	0.2	GO:0044326	dendritic spine neck(GO:0044326)
0.0	0.3	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	1.1	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	1.5	GO:0001772	immunological synapse(GO:0001772)
0.0	0.8	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	4.3	GO:0044306	neuron projection terminus(GO:0044306)
0.0	0.3	GO:0045095	keratin filament(GO:0045095)
0.0	1.2	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	3.9	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0	0.3	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.3	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.2	GO:0097255	R2TP complex(GO:0097255)
0.0	2.2	GO:0016605	PML body(GO:0016605)
0.0	0.4	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.0	1.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.3	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.3	GO:0042629	mast cell granule(GO:0042629)
0.0	0.9	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	1.1	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	2.2	GO:0072562	blood microparticle(GO:0072562)
0.0	0.4	GO:0030673	axolemma(GO:0030673)
0.0	0.4	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.3	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.5	GO:0010494	cytoplasmic stress granule(GO:0010494)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	4.3	GO:0019238	cyclohydrolase activity(GO:0019238)
0.6	4.8	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.5	1.4	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.4	2.7	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.4	1.2	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.4	21.7	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.3	0.8	GO:0016418	S-acetyltransferase activity(GO:0016418)
0.2	1.7	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.2	0.8	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.2	1.9	GO:0019237	centromeric DNA binding(GO:0019237)
0.2	1.0	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.2	1.2	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2	30.0	GO:0003823	antigen binding(GO:0003823)
0.1	1.6	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	3.8	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	0.7	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1	1.2	GO:0070883	pre-miRNA binding(GO:0070883)
0.1	0.4	GO:0047977	hepoxilin-epoxide hydrolase activity(GO:0047977)
0.1	0.3	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.1	1.2	GO:0031852	mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1	0.5	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	0.6	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1	0.7	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.1	1.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	0.8	GO:0000150	recombinase activity(GO:0000150)
0.1	0.3	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
0.1	0.4	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.9	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.1	0.5	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800) selenium binding(GO:0008430)
0.1	0.4	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.0	1.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.7	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.3	GO:0004996	thyroid-stimulating hormone receptor activity(GO:0004996)
0.0	0.5	GO:0008061	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.0	0.4	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.3	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	1.1	GO:0071949	FAD binding(GO:0071949)
0.0	0.5	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.2	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.3	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	6.2	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.2	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.0	1.0	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.3	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.3	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.2	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.1	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.0	0.2	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	5.0	GO:0005178	integrin binding(GO:0005178)
0.0	0.2	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.7	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.3	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.3	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.9	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.2	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	1.4	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.5	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.1	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
0.0	1.1	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.4	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	1.0	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.7	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.1	GO:0015140	malate transmembrane transporter activity(GO:0015140)