ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
TLX2 Links Ensembl NCBI GeneCards UniProt	ENSG00000115297.9	TLX2

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TLX2	hg19_v2_chr2_+_74741569_74741620	0.40	1.3e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr10_-_47173994	3.44	ENST00000414655.2 ENST00000545298.1 ENST00000359178.4 ENST00000358140.4 ENST00000503031.1	ANXA8L1 LINC00842	annexin A8-like 1 long intergenic non-protein coding RNA 842
chr10_+_47746929	3.10	ENST00000340243.6 ENST00000374277.5 ENST00000449464.2 ENST00000538825.1 ENST00000335083.5	ANXA8L2 AL603965.1	annexin A8-like 2 Protein LOC100996760
chr3_-_182880541	2.80	ENST00000470251.1 ENST00000265598.3	LAMP3	lysosomal-associated membrane protein 3
chr10_+_48255253	2.56	ENST00000357718.4 ENST00000344416.5 ENST00000456111.2 ENST00000374258.3	ANXA8 AL591684.1	annexin A8 Protein LOC100996760
chr6_+_116692102	2.53	ENST00000359564.2	DSE	dermatan sulfate epimerase
chr11_+_35160709	2.42	ENST00000415148.2 ENST00000433354.2 ENST00000449691.2 ENST00000437706.2 ENST00000360158.4 ENST00000428726.2 ENST00000526669.2 ENST00000433892.2 ENST00000278386.6 ENST00000434472.2 ENST00000352818.4 ENST00000442151.2	CD44	CD44 molecule (Indian blood group)
chr8_+_86376081	2.37	ENST00000285379.5	CA2	carbonic anhydrase II
chr6_-_32498046	2.17	ENST00000374975.3	HLA-DRB5	major histocompatibility complex, class II, DR beta 5
chr11_+_60223225	1.97	ENST00000524807.1 ENST00000345732.4	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr1_-_153363452	1.97	ENST00000368732.1 ENST00000368733.3	S100A8	S100 calcium binding protein A8
chr16_-_11681023	1.93	ENST00000570904.1 ENST00000574701.1	LITAF	lipopolysaccharide-induced TNF factor
chr16_-_11680791	1.81	ENST00000571976.1 ENST00000413364.2	LITAF	lipopolysaccharide-induced TNF factor
chr3_+_48507621	1.76	ENST00000456089.1	TREX1	three prime repair exonuclease 1
chr11_+_60223312	1.74	ENST00000532491.1 ENST00000532073.1 ENST00000534668.1 ENST00000528313.1 ENST00000533306.1	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr6_-_138428613	1.74	ENST00000421351.3	PERP	PERP, TP53 apoptosis effector
chr1_+_86889769	1.54	ENST00000370565.4	CLCA2	chloride channel accessory 2
chr1_-_25291475	1.53	ENST00000338888.3 ENST00000399916.1	RUNX3	runt-related transcription factor 3
chr1_+_152881014	1.50	ENST00000368764.3 ENST00000392667.2	IVL	involucrin
chr3_+_48507210	1.50	ENST00000433541.1 ENST00000422277.2 ENST00000436480.2 ENST00000444177.1	TREX1	three prime repair exonuclease 1
chr16_-_11680759	1.49	ENST00000571459.1 ENST00000570798.1 ENST00000572255.1 ENST00000574763.1 ENST00000574703.1 ENST00000571277.1 ENST00000381810.3	LITAF	lipopolysaccharide-induced TNF factor
chr3_+_121796697	1.46	ENST00000482356.1 ENST00000393627.2	CD86	CD86 molecule
chr1_-_68698222	1.38	ENST00000370976.3 ENST00000354777.2 ENST00000262348.4 ENST00000540432.1	WLS	wntless Wnt ligand secretion mediator
chr6_-_32920794	1.33	ENST00000395305.3 ENST00000395303.3 ENST00000374843.4 ENST00000429234.1	HLA-DMA XXbac-BPG181M17.5	major histocompatibility complex, class II, DM alpha Uncharacterized protein
chr14_-_67859422	1.32	ENST00000556532.1	PLEK2	pleckstrin 2
chr1_+_207627697	1.31	ENST00000458541.2	CR2	complement component (3d/Epstein Barr virus) receptor 2
chr20_+_44746939	1.30	ENST00000372276.3	CD40	CD40 molecule, TNF receptor superfamily member 5
chr12_-_50677255	1.29	ENST00000551691.1 ENST00000394943.3 ENST00000341247.4	LIMA1	LIM domain and actin binding 1
chr1_+_153330322	1.27	ENST00000368738.3	S100A9	S100 calcium binding protein A9
chr1_+_207627575	1.27	ENST00000367058.3 ENST00000367057.3 ENST00000367059.3	CR2	complement component (3d/Epstein Barr virus) receptor 2
chr20_-_1373606	1.26	ENST00000381715.1 ENST00000439640.2 ENST00000381719.3	FKBP1A	FK506 binding protein 1A, 12kDa
chr20_+_44746885	1.26	ENST00000372285.3	CD40	CD40 molecule, TNF receptor superfamily member 5
chr4_-_36246060	1.24	ENST00000303965.4	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr20_-_14318248	1.24	ENST00000378053.3 ENST00000341420.4	FLRT3	fibronectin leucine rich transmembrane protein 3
chr11_+_69924639	1.24	ENST00000538023.1 ENST00000398543.2	ANO1	anoctamin 1, calcium activated chloride channel
chr3_-_107809816	1.21	ENST00000361309.5 ENST00000355354.7	CD47	CD47 molecule
chr3_+_121774202	1.19	ENST00000469710.1 ENST00000493101.1 ENST00000330540.2 ENST00000264468.5	CD86	CD86 molecule
chr6_-_32634425	1.16	ENST00000399082.3 ENST00000399079.3 ENST00000374943.4 ENST00000434651.2	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1
chr12_-_95611149	1.15	ENST00000549499.1 ENST00000343958.4 ENST00000546711.1	FGD6	FYVE, RhoGEF and PH domain containing 6
chr20_-_1373682	1.13	ENST00000381724.3	FKBP1A	FK506 binding protein 1A, 12kDa
chr8_+_26435359	1.13	ENST00000311151.5	DPYSL2	dihydropyrimidinase-like 2
chr4_-_105416039	1.11	ENST00000394767.2	CXXC4	CXXC finger protein 4
chr15_+_41136586	1.11	ENST00000431806.1	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr7_+_155090271	1.09	ENST00000476756.1	INSIG1	insulin induced gene 1
chr17_-_33760164	1.07	ENST00000445092.1 ENST00000394562.1 ENST00000447040.2	SLFN12	schlafen family member 12
chr14_+_61789382	1.04	ENST00000555082.1	PRKCH	protein kinase C, eta
chr17_-_33760269	1.02	ENST00000452764.3	SLFN12	schlafen family member 12
chr15_-_38856836	1.00	ENST00000450598.2 ENST00000559830.1 ENST00000558164.1 ENST00000310803.5	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr7_-_120498357	0.99	ENST00000415871.1 ENST00000222747.3 ENST00000430985.1	TSPAN12	tetraspanin 12
chr4_-_90758227	0.98	ENST00000506691.1 ENST00000394986.1 ENST00000506244.1 ENST00000394989.2 ENST00000394991.3	SNCA	synuclein, alpha (non A4 component of amyloid precursor)
chr19_+_47104553	0.96	ENST00000598871.1 ENST00000594523.1	CALM3	calmodulin 3 (phosphorylase kinase, delta)
chr19_-_11688447	0.95	ENST00000590420.1	ACP5	acid phosphatase 5, tartrate resistant
chr3_+_69134124	0.92	ENST00000478935.1	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5
chr4_-_90758118	0.91	ENST00000420646.2	SNCA	synuclein, alpha (non A4 component of amyloid precursor)
chr1_+_32739733	0.91	ENST00000333070.4	LCK	lymphocyte-specific protein tyrosine kinase
chr15_-_82555000	0.90	ENST00000557844.1 ENST00000359445.3 ENST00000268206.7	EFTUD1	elongation factor Tu GTP binding domain containing 1
chr17_-_33759509	0.89	ENST00000304905.5	SLFN12	schlafen family member 12
chr3_+_69134080	0.89	ENST00000273258.3	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5
chr7_+_90225796	0.86	ENST00000380050.3	CDK14	cyclin-dependent kinase 14
chr11_+_128563652	0.84	ENST00000527786.2	FLI1	Fli-1 proto-oncogene, ETS transcription factor
chr17_-_46507537	0.84	ENST00000336915.6	SKAP1	src kinase associated phosphoprotein 1
chr19_+_44081344	0.83	ENST00000599207.1	PINLYP	phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr12_-_57522813	0.82	ENST00000556155.1	STAT6	signal transducer and activator of transcription 6, interleukin-4 induced
chr20_+_43104508	0.81	ENST00000262605.4 ENST00000372904.3	TTPAL	tocopherol (alpha) transfer protein-like
chr14_+_65171315	0.79	ENST00000394691.1	PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr2_-_225811747	0.78	ENST00000409592.3	DOCK10	dedicator of cytokinesis 10
chr6_-_31550192	0.78	ENST00000429299.2 ENST00000446745.2	LTB	lymphotoxin beta (TNF superfamily, member 3)
chr15_+_81475047	0.77	ENST00000559388.1	IL16	interleukin 16
chrX_+_24483338	0.77	ENST00000379162.4 ENST00000441463.2	PDK3	pyruvate dehydrogenase kinase, isozyme 3
chr1_-_32169920	0.76	ENST00000373672.3 ENST00000373668.3	COL16A1	collagen, type XVI, alpha 1
chr5_-_151138200	0.76	ENST00000313115.6 ENST00000522710.1	ATOX1	antioxidant 1 copper chaperone
chr1_-_32169761	0.76	ENST00000271069.6	COL16A1	collagen, type XVI, alpha 1
chr16_-_24942273	0.75	ENST00000571406.1	ARHGAP17	Rho GTPase activating protein 17
chr2_+_102928009	0.74	ENST00000404917.2 ENST00000447231.1	IL1RL1	interleukin 1 receptor-like 1
chr2_+_219433281	0.71	ENST00000273064.6 ENST00000509807.2 ENST00000542068.1	RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr19_-_11688500	0.71	ENST00000433365.2	ACP5	acid phosphatase 5, tartrate resistant
chr1_-_31230650	0.69	ENST00000294507.3	LAPTM5	lysosomal protein transmembrane 5
chr14_+_65171099	0.68	ENST00000247226.7	PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr3_+_50192537	0.67	ENST00000002829.3	SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr1_-_68698197	0.67	ENST00000370973.2 ENST00000370971.1	WLS	wntless Wnt ligand secretion mediator
chr3_+_50192499	0.66	ENST00000413852.1	SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr22_-_45636650	0.66	ENST00000336156.5	KIAA0930	KIAA0930
chr2_+_219110149	0.64	ENST00000456575.1	ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa
chr10_-_33623564	0.63	ENST00000374875.1 ENST00000374822.4	NRP1	neuropilin 1
chr20_-_1373726	0.63	ENST00000400137.4	FKBP1A	FK506 binding protein 1A, 12kDa
chr16_-_24942411	0.62	ENST00000571843.1	ARHGAP17	Rho GTPase activating protein 17
chr17_+_7211280	0.61	ENST00000419711.2 ENST00000571955.1 ENST00000573714.1	EIF5A	eukaryotic translation initiation factor 5A
chr3_-_48481518	0.61	ENST00000412398.2 ENST00000395696.1	CCDC51	coiled-coil domain containing 51
chr14_+_88471468	0.60	ENST00000267549.3	GPR65	G protein-coupled receptor 65
chr22_+_43547520	0.60	ENST00000337554.3 ENST00000396265.3 ENST00000583777.1	TSPO	translocator protein (18kDa)
chr3_+_118892362	0.59	ENST00000497685.1 ENST00000264234.3	UPK1B	uroplakin 1B
chr14_+_23340822	0.59	ENST00000359591.4	LRP10	low density lipoprotein receptor-related protein 10
chr16_+_66400533	0.59	ENST00000341529.3	CDH5	cadherin 5, type 2 (vascular endothelium)
chr8_-_55014336	0.58	ENST00000343231.6	LYPLA1	lysophospholipase I
chr4_+_78078304	0.57	ENST00000316355.5 ENST00000354403.5 ENST00000502280.1	CCNG2	cyclin G2
chr19_-_51512804	0.57	ENST00000594211.1 ENST00000376832.4	KLK9	kallikrein-related peptidase 9
chr3_-_105588231	0.56	ENST00000545639.1 ENST00000394027.3 ENST00000438603.1 ENST00000447441.1 ENST00000443752.1	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr1_-_85742773	0.55	ENST00000370580.1	BCL10	B-cell CLL/lymphoma 10
chr18_+_29077990	0.55	ENST00000261590.8	DSG2	desmoglein 2
chr19_-_45953983	0.54	ENST00000592083.1	ERCC1	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr4_+_169552748	0.54	ENST00000504519.1 ENST00000512127.1	PALLD	palladin, cytoskeletal associated protein
chr1_+_152486950	0.53	ENST00000368790.3	CRCT1	cysteine-rich C-terminal 1
chr11_-_89223883	0.53	ENST00000528341.1	NOX4	NADPH oxidase 4
chr19_+_1067271	0.53	ENST00000536472.1 ENST00000590214.1	HMHA1	histocompatibility (minor) HA-1
chr8_+_74903580	0.53	ENST00000284818.2 ENST00000518893.1	LY96	lymphocyte antigen 96
chr5_+_159656437	0.53	ENST00000402432.3	FABP6	fatty acid binding protein 6, ileal
chr20_-_62710832	0.52	ENST00000395042.1	RGS19	regulator of G-protein signaling 19
chr4_-_84205905	0.52	ENST00000311461.7 ENST00000311469.4 ENST00000439031.2	COQ2	coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
chr19_+_2389784	0.50	ENST00000332578.3	TMPRSS9	transmembrane protease, serine 9
chr6_-_143266297	0.50	ENST00000367603.2	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2
chr22_+_31477296	0.49	ENST00000426927.1 ENST00000440425.1 ENST00000358743.1 ENST00000347557.2 ENST00000333137.7	SMTN	smoothelin
chr19_-_37019562	0.49	ENST00000523638.1	ZNF260	zinc finger protein 260
chr7_+_99971129	0.49	ENST00000394000.2 ENST00000350573.2	PILRA	paired immunoglobin-like type 2 receptor alpha
chr19_+_47104493	0.49	ENST00000291295.9 ENST00000597743.1	CALM3	calmodulin 3 (phosphorylase kinase, delta)
chr8_+_27183033	0.48	ENST00000420218.2	PTK2B	protein tyrosine kinase 2 beta
chr11_-_33743952	0.47	ENST00000534312.1	CD59	CD59 molecule, complement regulatory protein
chr12_+_12938541	0.47	ENST00000356591.4	APOLD1	apolipoprotein L domain containing 1
chr6_-_6007200	0.46	ENST00000244766.2	NRN1	neuritin 1
chr19_+_1026298	0.46	ENST00000263097.4	CNN2	calponin 2
chr7_+_6414128	0.46	ENST00000348035.4 ENST00000356142.4	RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
chr9_+_2621798	0.46	ENST00000382100.3	VLDLR	very low density lipoprotein receptor
chr19_+_1026566	0.45	ENST00000348419.3 ENST00000565096.2 ENST00000562958.2 ENST00000562075.2 ENST00000607102.1	CNN2	calponin 2
chr8_+_38758737	0.45	ENST00000521746.1 ENST00000420274.1	PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr1_-_17304771	0.45	ENST00000375534.3	MFAP2	microfibrillar-associated protein 2
chr11_-_22851367	0.45	ENST00000354193.4	SVIP	small VCP/p97-interacting protein
chr10_-_50970322	0.44	ENST00000374103.4	OGDHL	oxoglutarate dehydrogenase-like
chr8_-_55014415	0.44	ENST00000522007.1 ENST00000521898.1 ENST00000518546.1 ENST00000316963.3	LYPLA1	lysophospholipase I
chr9_+_116267536	0.44	ENST00000374136.1	RGS3	regulator of G-protein signaling 3
chr10_+_64133934	0.43	ENST00000395254.3 ENST00000395255.3 ENST00000410046.3	ZNF365	zinc finger protein 365
chr19_+_36203830	0.42	ENST00000262630.3	ZBTB32	zinc finger and BTB domain containing 32
chr19_-_37019136	0.42	ENST00000592282.1	ZNF260	zinc finger protein 260
chr7_+_89783689	0.41	ENST00000297205.2	STEAP1	six transmembrane epithelial antigen of the prostate 1
chr8_+_27182862	0.41	ENST00000521164.1 ENST00000346049.5	PTK2B	protein tyrosine kinase 2 beta
chr11_-_33744256	0.41	ENST00000415002.2 ENST00000437761.2 ENST00000445143.2	CD59	CD59 molecule, complement regulatory protein
chr1_+_199996702	0.41	ENST00000367362.3	NR5A2	nuclear receptor subfamily 5, group A, member 2
chr10_+_71075552	0.41	ENST00000298649.3	HK1	hexokinase 1
chr13_-_103426081	0.41	ENST00000376022.1 ENST00000376021.4	TEX30	testis expressed 30
chr10_-_50970382	0.41	ENST00000419399.1 ENST00000432695.1	OGDHL	oxoglutarate dehydrogenase-like
chr7_-_11871815	0.41	ENST00000423059.4	THSD7A	thrombospondin, type I, domain containing 7A
chr16_-_68269971	0.40	ENST00000565858.1	ESRP2	epithelial splicing regulatory protein 2
chr16_+_19183671	0.40	ENST00000562711.2	SYT17	synaptotagmin XVII
chr14_+_76618242	0.39	ENST00000557542.1 ENST00000557263.1 ENST00000557207.1 ENST00000312858.5 ENST00000261530.7	GPATCH2L	G patch domain containing 2-like
chr11_+_123396528	0.39	ENST00000322282.7 ENST00000529750.1	GRAMD1B	GRAM domain containing 1B
chr13_-_103426112	0.39	ENST00000376032.4 ENST00000376029.3	TEX30	testis expressed 30
chr9_+_116225999	0.39	ENST00000317613.6	RGS3	regulator of G-protein signaling 3
chr1_+_155829286	0.38	ENST00000368324.4	SYT11	synaptotagmin XI
chr11_+_67070919	0.38	ENST00000308127.4 ENST00000308298.7	SSH3	slingshot protein phosphatase 3
chr12_-_54673871	0.37	ENST00000209875.4	CBX5	chromobox homolog 5
chr4_+_2814011	0.37	ENST00000502260.1 ENST00000435136.2	SH3BP2	SH3-domain binding protein 2
chr17_+_7452336	0.36	ENST00000293826.4	TNFSF12-TNFSF13	TNFSF12-TNFSF13 readthrough
chr6_-_16761678	0.36	ENST00000244769.4 ENST00000436367.1	ATXN1	ataxin 1
chr15_-_72563585	0.36	ENST00000287196.9 ENST00000260376.7	PARP6	poly (ADP-ribose) polymerase family, member 6
chr19_-_6767516	0.36	ENST00000245908.6	SH2D3A	SH2 domain containing 3A
chr20_+_56884752	0.36	ENST00000244040.3	RAB22A	RAB22A, member RAS oncogene family
chr17_+_7452442	0.35	ENST00000557233.1	TNFSF12	tumor necrosis factor (ligand) superfamily, member 12
chr1_-_154832316	0.35	ENST00000361147.4	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr11_+_67071050	0.35	ENST00000376757.5	SSH3	slingshot protein phosphatase 3
chr19_-_59066452	0.35	ENST00000312547.2	CHMP2A	charged multivesicular body protein 2A
chr5_-_102455801	0.35	ENST00000508629.1 ENST00000399004.2	GIN1	gypsy retrotransposon integrase 1
chr5_+_131409476	0.34	ENST00000296871.2	CSF2	colony stimulating factor 2 (granulocyte-macrophage)
chr1_-_6526192	0.34	ENST00000377782.3 ENST00000351959.5 ENST00000356876.3	TNFRSF25	tumor necrosis factor receptor superfamily, member 25
chr12_+_9144626	0.34	ENST00000543895.1	KLRG1	killer cell lectin-like receptor subfamily G, member 1
chr19_-_59066327	0.34	ENST00000596708.1 ENST00000601220.1 ENST00000597848.1	CHMP2A	charged multivesicular body protein 2A
chr8_-_27630102	0.33	ENST00000356537.4 ENST00000522915.1 ENST00000539095.1	CCDC25	coiled-coil domain containing 25
chrX_+_153665248	0.33	ENST00000447750.2	GDI1	GDP dissociation inhibitor 1
chr16_+_58283814	0.33	ENST00000443128.2 ENST00000219299.4	CCDC113	coiled-coil domain containing 113
chr7_-_32110451	0.31	ENST00000396191.1 ENST00000396182.2	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa
chr14_+_54863667	0.31	ENST00000335183.6	CDKN3	cyclin-dependent kinase inhibitor 3
chr3_-_36986534	0.31	ENST00000429976.2 ENST00000301807.6	TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1
chr1_+_160160283	0.31	ENST00000368079.3	CASQ1	calsequestrin 1 (fast-twitch, skeletal muscle)
chr1_+_199996733	0.30	ENST00000236914.3	NR5A2	nuclear receptor subfamily 5, group A, member 2
chr6_+_13272904	0.30	ENST00000379335.3 ENST00000379329.1	PHACTR1	phosphatase and actin regulator 1
chr11_-_133826852	0.30	ENST00000533871.2 ENST00000321016.8	IGSF9B	immunoglobulin superfamily, member 9B
chr1_+_16062820	0.30	ENST00000294454.5	SLC25A34	solute carrier family 25, member 34
chr9_+_2622085	0.30	ENST00000382099.2	VLDLR	very low density lipoprotein receptor
chr21_+_43639211	0.30	ENST00000450121.1 ENST00000398449.3 ENST00000361802.2	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
chr14_-_106622419	0.29	ENST00000390604.2	IGHV3-16	immunoglobulin heavy variable 3-16 (non-functional)
chr19_-_6767431	0.29	ENST00000437152.3 ENST00000597687.1	SH2D3A	SH2 domain containing 3A
chr7_-_150777949	0.29	ENST00000482571.1	FASTK	Fas-activated serine/threonine kinase
chr1_-_226076843	0.29	ENST00000272134.5	LEFTY1	left-right determination factor 1
chr5_+_133451254	0.28	ENST00000517851.1 ENST00000521639.1 ENST00000522375.1 ENST00000378560.4 ENST00000432532.2 ENST00000520958.1 ENST00000518915.1 ENST00000395023.1	TCF7	transcription factor 7 (T-cell specific, HMG-box)
chr1_+_9711781	0.28	ENST00000536656.1 ENST00000377346.4	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
chr7_-_32111009	0.28	ENST00000396184.3 ENST00000396189.2 ENST00000321453.7	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa
chr19_-_52133588	0.28	ENST00000570106.2	SIGLEC5	sialic acid binding Ig-like lectin 5
chr14_+_54863682	0.28	ENST00000543789.2 ENST00000442975.2 ENST00000458126.2 ENST00000556102.2	CDKN3	cyclin-dependent kinase inhibitor 3
chr19_+_16435625	0.28	ENST00000248071.5 ENST00000592003.1	KLF2	Kruppel-like factor 2
chr7_-_150777920	0.28	ENST00000353841.2 ENST00000297532.6	FASTK	Fas-activated serine/threonine kinase
chr3_-_122233723	0.28	ENST00000493510.1 ENST00000344337.6 ENST00000476916.1 ENST00000465882.1	KPNA1	karyopherin alpha 1 (importin alpha 5)
chrX_+_151999511	0.27	ENST00000370274.3 ENST00000440023.1 ENST00000432467.1	NSDHL	NAD(P) dependent steroid dehydrogenase-like
chr1_+_160160346	0.27	ENST00000368078.3	CASQ1	calsequestrin 1 (fast-twitch, skeletal muscle)
chr21_-_38445470	0.27	ENST00000399098.1	PIGP	phosphatidylinositol glycan anchor biosynthesis, class P
chr12_+_6602517	0.27	ENST00000315579.5 ENST00000539714.1	NCAPD2	non-SMC condensin I complex, subunit D2
chr7_+_99971068	0.26	ENST00000198536.2 ENST00000453419.1	PILRA	paired immunoglobin-like type 2 receptor alpha
chr19_-_42931567	0.26	ENST00000244289.4	LIPE	lipase, hormone-sensitive
chr12_+_113229737	0.26	ENST00000551052.1 ENST00000415485.3	RPH3A	rabphilin 3A homolog (mouse)
chr6_+_106546808	0.26	ENST00000369089.3	PRDM1	PR domain containing 1, with ZNF domain
chr2_+_10262857	0.26	ENST00000304567.5	RRM2	ribonucleotide reductase M2
chr1_+_948803	0.24	ENST00000379389.4	ISG15	ISG15 ubiquitin-like modifier
chr15_-_34502278	0.24	ENST00000559515.1 ENST00000256544.3 ENST00000560108.1 ENST00000559462.1	KATNBL1	katanin p80 subunit B-like 1
chr12_-_33049690	0.24	ENST00000070846.6 ENST00000340811.4	PKP2	plakophilin 2
chr8_+_22423168	0.24	ENST00000518912.1 ENST00000428103.1	SORBS3	sorbin and SH3 domain containing 3

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	5.2	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
0.6	3.0	GO:1990425	ryanodine receptor complex(GO:1990425)
0.4	2.6	GO:0043196	varicosity(GO:0043196)
0.3	2.8	GO:0097208	alveolar lamellar body(GO:0097208)
0.3	2.4	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3	1.3	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.3	0.9	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2	4.8	GO:0042613	MHC class II protein complex(GO:0042613)
0.2	1.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.2	0.6	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2	1.5	GO:0005593	FACIT collagen trimer(GO:0005593)
0.1	0.6	GO:0014802	terminal cisterna(GO:0014802)
0.1	0.9	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.1	0.6	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
0.1	2.5	GO:0030057	desmosome(GO:0030057)
0.1	0.4	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.1	0.4	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.1	0.3	GO:0000799	nuclear condensin complex(GO:0000799)
0.1	0.3	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1	0.6	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1	1.9	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.7	GO:0002116	semaphorin receptor complex(GO:0002116) sorting endosome(GO:0097443)
0.1	0.9	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	0.9	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	1.2	GO:0044295	axonal growth cone(GO:0044295)
0.1	0.7	GO:0000815	ESCRT III complex(GO:0000815)
0.1	0.2	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.1	0.6	GO:0005642	annulate lamellae(GO:0005642)
0.1	1.5	GO:0001533	cornified envelope(GO:0001533)
0.0	0.2	GO:0031673	H zone(GO:0031673)
0.0	1.3	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.9	GO:0000242	pericentriolar material(GO:0000242)
0.0	1.5	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.2	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.0	0.2	GO:0010370	perinucleolar chromocenter(GO:0010370)
0.0	0.6	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.5	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.4	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	1.0	GO:0042629	mast cell granule(GO:0042629)
0.0	0.8	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.3	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.3	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	1.8	GO:0005902	microvillus(GO:0005902)
0.0	0.8	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.8	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	6.3	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.5	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.0	0.2	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.3	GO:0005869	dynactin complex(GO:0005869)
0.0	0.5	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.2	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	2.1	GO:0005903	brush border(GO:0005903)
0.0	2.0	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.4	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.4	GO:0097228	sperm principal piece(GO:0097228)
0.0	0.3	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:1990130	Iml1 complex(GO:1990130)
0.0	0.3	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	2.0	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	1.0	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	0.2	GO:0036038	MKS complex(GO:0036038)
0.0	1.1	GO:0031410	cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.0	GO:0055087	Ski complex(GO:0055087)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.0	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.3	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.0	0.1	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	1.4	GO:0005923	bicellular tight junction(GO:0005923)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	3.2	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.8	2.5	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.5	3.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.4	1.9	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.4	1.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.3	0.9	GO:0002113	interleukin-33 binding(GO:0002113)
0.3	0.9	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3	2.4	GO:0004064	arylesterase activity(GO:0004064)
0.3	1.0	GO:0034437	glycoprotein transporter activity(GO:0034437)
0.3	0.8	GO:0032767	copper-dependent protein binding(GO:0032767)
0.2	1.2	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.2	0.7	GO:0033867	Fas-activated serine/threonine kinase activity(GO:0033867)
0.2	3.0	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.2	1.0	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.2	0.8	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2	2.5	GO:0004875	complement receptor activity(GO:0004875)
0.2	4.3	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2	0.9	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2	5.2	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.2	2.6	GO:0045499	chemorepellent activity(GO:0045499)
0.2	2.1	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.2	0.9	GO:0042610	CD8 receptor binding(GO:0042610)
0.1	1.8	GO:0008199	ferric iron binding(GO:0008199)
0.1	0.4	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1	1.0	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1	1.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	5.2	GO:0050699	WW domain binding(GO:0050699)
0.1	1.2	GO:0032395	MHC class II receptor activity(GO:0032395)
0.1	3.1	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	0.4	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1	0.6	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1	4.5	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	0.3	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.1	0.8	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	2.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.5	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1	0.4	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.1	0.6	GO:0005497	androgen binding(GO:0005497)
0.1	0.7	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.1	0.4	GO:0034046	poly(G) binding(GO:0034046)
0.1	2.1	GO:0042605	peptide antigen binding(GO:0042605)
0.1	1.7	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.1	0.3	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.8	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	3.2	GO:0015026	coreceptor activity(GO:0015026)
0.1	0.5	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.2	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.1	0.6	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.5	GO:0019826	oxygen sensor activity(GO:0019826)
0.1	1.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	0.2	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1	0.8	GO:0042609	CD4 receptor binding(GO:0042609)
0.1	0.4	GO:0008865	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0	0.1	GO:0036134	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0	0.1	GO:0015234	thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.0	0.2	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0	0.8	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.2	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	1.8	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.4	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.2	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	1.0	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.2	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.0	0.6	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.8	GO:0001848	complement binding(GO:0001848)
0.0	0.8	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	1.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.3	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.3	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.4	GO:0032052	bile acid binding(GO:0032052)
0.0	0.2	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.2	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.5	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	2.3	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.2	GO:0031386	protein tag(GO:0031386)
0.0	0.2	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.9	GO:0030332	cyclin binding(GO:0030332)
0.0	0.2	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.3	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0	0.3	GO:0017166	vinculin binding(GO:0017166)
0.0	0.8	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.6	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.5	GO:0042169	SH2 domain binding(GO:0042169)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.0	PID ALK2 PATHWAY	ALK2 signaling events
0.1	3.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	0.8	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	2.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	3.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	2.8	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.6	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	2.9	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	3.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	1.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	7.2	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	2.1	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.7	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	1.1	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	2.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	1.0	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	1.2	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.8	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.6	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.3	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.0	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.5	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.3	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.3	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.6	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	1.7	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.3	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.5	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.4	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.7	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.5	PID PTP1B PATHWAY	Signaling events mediated by PTP1B

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	3.2	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.9	2.6	GO:1900138	negative regulation of phospholipase A2 activity(GO:1900138)
0.8	2.4	GO:0042938	dipeptide transport(GO:0042938)
0.7	2.1	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.5	1.5	GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.5	3.2	GO:0032119	sequestering of zinc ion(GO:0032119)
0.4	1.9	GO:0051622	negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.4	2.6	GO:0033590	response to cobalamin(GO:0033590)
0.4	1.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.3	1.3	GO:0002503	peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.3	1.7	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.3	2.4	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3	0.8	GO:0015680	intracellular copper ion transport(GO:0015680)
0.3	3.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.3	2.0	GO:0036484	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.2	1.2	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.2	2.5	GO:0002934	desmosome organization(GO:0002934)
0.2	0.7	GO:1903722	regulation of centriole elongation(GO:1903722)
0.2	0.9	GO:2000537	regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.2	0.9	GO:0001971	negative regulation of activation of membrane attack complex(GO:0001971)
0.2	0.8	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
0.2	0.8	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2	0.2	GO:1902567	negative regulation of eosinophil activation(GO:1902567)
0.2	1.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.2	1.8	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.2	1.0	GO:0034436	glycoprotein transport(GO:0034436)
0.2	1.0	GO:0032252	secretory granule localization(GO:0032252)
0.2	2.4	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.2	0.3	GO:0036518	chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.2	0.5	GO:0032707	negative regulation of interleukin-23 production(GO:0032707)
0.1	0.9	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
0.1	0.4	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1	5.4	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1	1.2	GO:0003344	pericardium morphogenesis(GO:0003344)
0.1	1.0	GO:0034351	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1	0.4	GO:1905154	negative regulation of membrane invagination(GO:1905154)
0.1	1.1	GO:0015705	iodide transport(GO:0015705)
0.1	0.6	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.1	0.8	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1	0.5	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	2.8	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.3	GO:0060374	mast cell differentiation(GO:0060374)
0.1	0.3	GO:0071409	cellular response to cycloheximide(GO:0071409)
0.1	0.5	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) post-embryonic hemopoiesis(GO:0035166) positive regulation of t-circle formation(GO:1904431)
0.1	0.8	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.1	0.2	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1	0.3	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.1	0.1	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
0.1	0.9	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.8	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.1	2.4	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1	0.2	GO:0045229	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1	0.4	GO:0098706	ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1	0.4	GO:0051136	regulation of NK T cell differentiation(GO:0051136)
0.1	0.1	GO:1902573	positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.1	1.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1	3.3	GO:0006298	mismatch repair(GO:0006298)
0.1	1.2	GO:0008228	opsonization(GO:0008228)
0.1	0.2	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1	0.6	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.4	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.1	0.2	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.1	0.6	GO:0014894	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1	1.5	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1	0.3	GO:0044336	embryonic genitalia morphogenesis(GO:0030538) canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1	0.2	GO:0061056	sclerotome development(GO:0061056)
0.1	0.7	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1	0.3	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.1	0.2	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1	0.5	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.0	0.1	GO:0070781	arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.0	0.1	GO:0015888	thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.0	0.6	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
0.0	0.3	GO:0010836	negative regulation of protein ADP-ribosylation(GO:0010836)
0.0	0.2	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0	0.3	GO:0098828	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.1	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.8	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.2	GO:0072143	mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.0	0.1	GO:0035522	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0	0.3	GO:0032482	Rab protein signal transduction(GO:0032482)
0.0	0.7	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.0	0.5	GO:0042118	endothelial cell activation(GO:0042118)
0.0	3.7	GO:0042100	B cell proliferation(GO:0042100)
0.0	0.8	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	1.5	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.0	0.2	GO:0035995	detection of muscle stretch(GO:0035995)
0.0	1.0	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0097501	hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) stress response to metal ion(GO:0097501)
0.0	0.1	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0	3.2	GO:0031295	T cell costimulation(GO:0031295)
0.0	0.3	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	1.2	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.2	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	0.2	GO:0071477	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0	0.2	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.5	GO:0006071	glycerol metabolic process(GO:0006071)
0.0	0.2	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.2	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0	0.3	GO:0015074	DNA integration(GO:0015074)
0.0	1.3	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
0.0	0.2	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.2	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0072092	ureteric bud invasion(GO:0072092)
0.0	0.5	GO:0003334	keratinocyte development(GO:0003334)
0.0	1.5	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
0.0	0.1	GO:0006836	neurotransmitter transport(GO:0006836)
0.0	0.2	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.0	0.4	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.0	0.1	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.3	GO:0045919	positive regulation of cytolysis(GO:0045919)
0.0	0.4	GO:0000075	cell cycle checkpoint(GO:0000075)
0.0	0.1	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.2	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.2	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.2	GO:0010968	regulation of microtubule nucleation(GO:0010968)
0.0	0.1	GO:1903061	regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.0	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.0	0.1	GO:0006370	7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0	0.7	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.0	GO:2001162	regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0	2.3	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.0	0.1	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.5	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.1	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.1	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.7	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.0	GO:0090298	late nucleophagy(GO:0044805) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) single-organism membrane invagination(GO:1902534)
0.0	0.2	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.5	GO:0019433	triglyceride catabolic process(GO:0019433)
0.0	0.3	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.1	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.0	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0	0.3	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.0	0.0	GO:0021779	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.2	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.0	GO:0001694	histamine biosynthetic process(GO:0001694)
0.0	0.0	GO:0051866	general adaptation syndrome(GO:0051866)
0.0	0.4	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.0	GO:0070253	somatostatin secretion(GO:0070253)
0.0	0.1	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.6	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.0	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	2.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	2.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	3.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	2.2	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	2.5	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.1	1.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.7	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.4	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.5	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.7	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	1.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.5	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	2.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.6	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	1.8	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.8	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	2.0	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.2	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.7	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.2	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.3	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	1.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)