ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
XBP1 Links Ensembl NCBI GeneCards UniProt	ENSG00000100219.12	XBP1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
XBP1	hg19_v2_chr22_-_29196030_29196121	-0.29	2.8e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr7_+_94023873	21.01	ENST00000297268.6	COL1A2	collagen, type I, alpha 2
chr10_+_89419370	7.45	ENST00000361175.4 ENST00000456849.1	PAPSS2	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr5_-_121413974	6.26	ENST00000231004.4	LOX	lysyl oxidase
chr22_+_38864041	5.84	ENST00000216014.4 ENST00000409006.3	KDELR3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr12_-_106641728	5.72	ENST00000378026.4	CKAP4	cytoskeleton-associated protein 4
chr11_+_69455855	5.44	ENST00000227507.2 ENST00000536559.1	CCND1	cyclin D1
chr5_+_119799927	3.92	ENST00000407149.2 ENST00000379551.2	PRR16	proline rich 16
chr15_-_60690932	3.85	ENST00000559818.1	ANXA2	annexin A2
chr3_-_149688502	3.84	ENST00000481767.1 ENST00000475518.1	PFN2	profilin 2
chr3_-_149688896	3.81	ENST00000239940.7	PFN2	profilin 2
chr7_+_128379346	3.78	ENST00000535011.2 ENST00000542996.2 ENST00000535623.1 ENST00000538546.1 ENST00000249364.4 ENST00000449187.2	CALU	calumenin
chr3_-_57583185	3.57	ENST00000463880.1	ARF4	ADP-ribosylation factor 4
chr7_-_19157248	3.34	ENST00000242261.5	TWIST1	twist family bHLH transcription factor 1
chr7_+_128379449	3.30	ENST00000479257.1	CALU	calumenin
chr7_-_27183263	3.26	ENST00000222726.3	HOXA5	homeobox A5
chr3_-_57583052	3.19	ENST00000496292.1 ENST00000489843.1	ARF4	ADP-ribosylation factor 4
chr3_+_105086056	3.14	ENST00000472644.2	ALCAM	activated leukocyte cell adhesion molecule
chr3_-_57583130	3.03	ENST00000303436.6	ARF4	ADP-ribosylation factor 4
chr12_-_56123444	2.73	ENST00000546457.1 ENST00000549117.1	CD63	CD63 molecule
chr1_-_144932014	2.68	ENST00000529945.1	PDE4DIP	phosphodiesterase 4D interacting protein
chr20_-_17662878	2.58	ENST00000377813.1 ENST00000377807.2 ENST00000360807.4 ENST00000398782.2	RRBP1	ribosome binding protein 1
chr5_-_9546180	2.54	ENST00000382496.5	SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr3_+_171758344	2.51	ENST00000336824.4 ENST00000423424.1	FNDC3B	fibronectin type III domain containing 3B
chr14_+_100259666	2.40	ENST00000262233.6 ENST00000334192.4	EML1	echinoderm microtubule associated protein like 1
chr6_+_116692102	2.39	ENST00000359564.2	DSE	dermatan sulfate epimerase
chr2_+_242254679	2.28	ENST00000428282.1 ENST00000360051.3	SEPT2	septin 2
chr7_-_30066233	2.23	ENST00000222803.5	FKBP14	FK506 binding protein 14, 22 kDa
chr16_-_66959429	2.21	ENST00000420652.1 ENST00000299759.6	RRAD	Ras-related associated with diabetes
chr19_+_16187816	2.02	ENST00000588410.1	TPM4	tropomyosin 4
chr10_-_128077024	2.00	ENST00000368679.4 ENST00000368676.4 ENST00000448723.1	ADAM12	ADAM metallopeptidase domain 12
chr15_-_60690163	1.99	ENST00000558998.1 ENST00000560165.1 ENST00000557986.1 ENST00000559780.1 ENST00000559467.1 ENST00000559956.1 ENST00000332680.4 ENST00000396024.3 ENST00000421017.2 ENST00000560466.1 ENST00000558132.1 ENST00000559113.1 ENST00000557906.1 ENST00000558558.1 ENST00000560468.1 ENST00000559370.1 ENST00000558169.1 ENST00000559725.1 ENST00000558985.1 ENST00000451270.2	ANXA2	annexin A2
chr2_-_20251744	1.96	ENST00000175091.4	LAPTM4A	lysosomal protein transmembrane 4 alpha
chr9_+_35732312	1.93	ENST00000353704.2	CREB3	cAMP responsive element binding protein 3
chr11_-_66056596	1.92	ENST00000471387.2 ENST00000359461.6 ENST00000376901.4	YIF1A	Yip1 interacting factor homolog A (S. cerevisiae)
chr17_-_40575535	1.91	ENST00000357037.5	PTRF	polymerase I and transcript release factor
chr5_-_93447333	1.90	ENST00000395965.3 ENST00000505869.1 ENST00000509163.1	FAM172A	family with sequence similarity 172, member A
chr20_-_17662705	1.90	ENST00000455029.2	RRBP1	ribosome binding protein 1
chr9_+_114393634	1.89	ENST00000556107.1 ENST00000374294.3	DNAJC25 DNAJC25-GNG10	DnaJ (Hsp40) homolog, subfamily C , member 25 DNAJC25-GNG10 readthrough
chr4_-_119757239	1.85	ENST00000280551.6	SEC24D	SEC24 family member D
chr4_-_119757322	1.85	ENST00000379735.5	SEC24D	SEC24 family member D
chr7_-_6523755	1.83	ENST00000436575.1 ENST00000258739.4	DAGLB KDELR2	diacylglycerol lipase, beta KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr2_+_242254507	1.82	ENST00000391973.2	SEPT2	septin 2
chr6_-_83902933	1.79	ENST00000512866.1 ENST00000510258.1 ENST00000503094.1 ENST00000283977.4 ENST00000513973.1 ENST00000508748.1	PGM3	phosphoglucomutase 3
chr11_+_207477	1.74	ENST00000526104.1	RIC8A	RIC8 guanine nucleotide exchange factor A
chr3_+_127771212	1.74	ENST00000243253.3 ENST00000481210.1	SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)
chr14_-_24664776	1.65	ENST00000530468.1 ENST00000528010.1 ENST00000396854.4 ENST00000524835.1 ENST00000261789.4 ENST00000525592.1	TM9SF1	transmembrane 9 superfamily member 1
chr12_-_133405288	1.65	ENST00000204726.3	GOLGA3	golgin A3
chr2_-_242254595	1.63	ENST00000441124.1 ENST00000391976.2	HDLBP	high density lipoprotein binding protein
chr11_-_66056478	1.57	ENST00000431556.2 ENST00000528575.1	YIF1A	Yip1 interacting factor homolog A (S. cerevisiae)
chr1_+_145575980	1.56	ENST00000393045.2	PIAS3	protein inhibitor of activated STAT, 3
chr1_+_145576007	1.55	ENST00000369298.1	PIAS3	protein inhibitor of activated STAT, 3
chr1_+_21835858	1.54	ENST00000539907.1 ENST00000540617.1 ENST00000374840.3	ALPL	alkaline phosphatase, liver/bone/kidney
chr14_-_24664540	1.52	ENST00000530563.1 ENST00000528895.1 ENST00000528669.1 ENST00000532632.1	TM9SF1	transmembrane 9 superfamily member 1
chr20_+_44044717	1.51	ENST00000279036.6 ENST00000279035.9 ENST00000372689.5 ENST00000545755.1 ENST00000341555.5 ENST00000535404.1 ENST00000543458.2 ENST00000432270.1	PIGT	phosphatidylinositol glycan anchor biosynthesis, class T
chr2_-_33824382	1.49	ENST00000238823.8	FAM98A	family with sequence similarity 98, member A
chr2_+_85132749	1.44	ENST00000233143.4	TMSB10	thymosin beta 10
chr2_-_33824336	1.41	ENST00000431950.1 ENST00000403368.1 ENST00000441530.2	FAM98A	family with sequence similarity 98, member A
chr3_+_33155525	1.39	ENST00000449224.1	CRTAP	cartilage associated protein
chr3_+_50284321	1.34	ENST00000451956.1	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr13_+_35516390	1.31	ENST00000540320.1 ENST00000400445.3 ENST00000310336.4	NBEA	neurobeachin
chr11_+_17298297	1.27	ENST00000529010.1	NUCB2	nucleobindin 2
chr17_+_8339189	1.24	ENST00000585098.1 ENST00000380025.4 ENST00000402554.3 ENST00000584866.1 ENST00000582490.1	NDEL1	nudE neurodevelopment protein 1-like 1
chr1_-_144932464	1.23	ENST00000479408.2	PDE4DIP	phosphodiesterase 4D interacting protein
chr15_+_79603404	1.23	ENST00000299705.5	TMED3	transmembrane emp24 protein transport domain containing 3
chr19_+_36606654	1.20	ENST00000588385.1 ENST00000585746.1	TBCB	tubulin folding cofactor B
chr20_+_25228669	1.18	ENST00000216962.4	PYGB	phosphorylase, glycogen; brain
chr6_+_33168637	1.18	ENST00000374677.3	SLC39A7	solute carrier family 39 (zinc transporter), member 7
chr6_+_33168597	1.14	ENST00000374675.3	SLC39A7	solute carrier family 39 (zinc transporter), member 7
chr18_-_34408902	1.13	ENST00000593035.1 ENST00000383056.3 ENST00000588909.1 ENST00000590337.1	TPGS2	tubulin polyglutamylase complex subunit 2
chr14_-_92506371	1.13	ENST00000267622.4	TRIP11	thyroid hormone receptor interactor 11
chr1_+_87170577	1.09	ENST00000482504.1	SH3GLB1	SH3-domain GRB2-like endophilin B1
chr6_+_83903061	1.07	ENST00000369724.4 ENST00000539997.1	RWDD2A	RWD domain containing 2A
chr11_+_17298255	1.06	ENST00000531172.1 ENST00000533738.2 ENST00000323688.6	NUCB2	nucleobindin 2
chr17_+_8339164	1.05	ENST00000582665.1 ENST00000334527.7 ENST00000299734.7	NDEL1	nudE neurodevelopment protein 1-like 1
chr18_-_34409116	1.00	ENST00000334295.4	TPGS2	tubulin polyglutamylase complex subunit 2
chr11_-_207221	0.99	ENST00000486280.1 ENST00000332865.6 ENST00000529614.2 ENST00000325147.9 ENST00000410108.1 ENST00000382762.3	BET1L	Bet1 golgi vesicular membrane trafficking protein-like
chr17_+_64298944	0.96	ENST00000413366.3	PRKCA	protein kinase C, alpha
chr6_+_132129151	0.96	ENST00000360971.2	ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr1_-_145039949	0.95	ENST00000313382.9	PDE4DIP	phosphodiesterase 4D interacting protein
chr14_+_102430855	0.95	ENST00000360184.4	DYNC1H1	dynein, cytoplasmic 1, heavy chain 1
chr7_-_6523688	0.93	ENST00000490996.1	KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr1_-_87379785	0.91	ENST00000401030.3 ENST00000370554.1	SEP15	Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr16_+_56965960	0.87	ENST00000439977.2 ENST00000344114.4 ENST00000300302.5 ENST00000379792.2	HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr17_+_46048376	0.87	ENST00000338399.4	CDK5RAP3	CDK5 regulatory subunit associated protein 3
chr2_-_99952769	0.86	ENST00000409434.1 ENST00000434323.1 ENST00000264255.3	TXNDC9	thioredoxin domain containing 9
chr5_-_115177496	0.80	ENST00000274459.4 ENST00000509910.1	ATG12	autophagy related 12
chr3_-_156272924	0.79	ENST00000467789.1 ENST00000265044.2	SSR3	signal sequence receptor, gamma (translocon-associated protein gamma)
chr14_+_50087468	0.78	ENST00000305386.2	MGAT2	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr11_-_68039364	0.77	ENST00000533310.1 ENST00000304271.6 ENST00000527280.1	C11orf24	chromosome 11 open reading frame 24
chr22_-_43253189	0.74	ENST00000437119.2 ENST00000429508.2 ENST00000454099.1 ENST00000263245.5	ARFGAP3	ADP-ribosylation factor GTPase activating protein 3
chrX_-_41782683	0.74	ENST00000378163.1 ENST00000378154.1	CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr6_-_33168391	0.72	ENST00000374685.4 ENST00000413614.2 ENST00000374680.3	RXRB	retinoid X receptor, beta
chr19_+_1026566	0.69	ENST00000348419.3 ENST00000565096.2 ENST00000562958.2 ENST00000562075.2 ENST00000607102.1	CNN2	calponin 2
chr1_+_26758790	0.68	ENST00000427245.2 ENST00000525682.2 ENST00000236342.7 ENST00000526219.1 ENST00000374185.3 ENST00000360009.2	DHDDS	dehydrodolichyl diphosphate synthase
chrX_-_153059958	0.67	ENST00000370092.3 ENST00000217901.5	IDH3G	isocitrate dehydrogenase 3 (NAD+) gamma
chr4_+_56262115	0.66	ENST00000506198.1 ENST00000381334.5 ENST00000542052.1	TMEM165	transmembrane protein 165
chr5_+_112196919	0.63	ENST00000505459.1 ENST00000282999.3 ENST00000515463.1	SRP19	signal recognition particle 19kDa
chr3_-_139108475	0.60	ENST00000515006.1 ENST00000513274.1 ENST00000514508.1 ENST00000507777.1 ENST00000512153.1 ENST00000333188.5	COPB2	coatomer protein complex, subunit beta 2 (beta prime)
chr10_-_30348439	0.58	ENST00000375377.1	KIAA1462	KIAA1462
chr15_-_75165651	0.57	ENST00000562363.1 ENST00000564529.1 ENST00000268099.9	SCAMP2	secretory carrier membrane protein 2
chr5_-_108745689	0.56	ENST00000361189.2	PJA2	praja ring finger 2, E3 ubiquitin protein ligase
chr1_+_6845384	0.55	ENST00000303635.7	CAMTA1	calmodulin binding transcription activator 1
chr19_+_33182823	0.54	ENST00000397061.3	NUDT19	nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr6_-_108279369	0.52	ENST00000369002.4	SEC63	SEC63 homolog (S. cerevisiae)
chrX_-_153059811	0.46	ENST00000427365.2 ENST00000444450.1 ENST00000370093.1	IDH3G	isocitrate dehydrogenase 3 (NAD+) gamma
chrX_+_153060090	0.44	ENST00000370086.3 ENST00000370085.3	SSR4	signal sequence receptor, delta
chr10_+_104678102	0.43	ENST00000433628.2	CNNM2	cyclin M2
chr4_+_26322185	0.43	ENST00000361572.6	RBPJ	recombination signal binding protein for immunoglobulin kappa J region
chr11_-_62599505	0.43	ENST00000377897.4 ENST00000394690.1 ENST00000541317.1 ENST00000294179.3	STX5	syntaxin 5
chr1_-_87380002	0.41	ENST00000331835.5	SEP15	Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr11_+_118443098	0.41	ENST00000392859.3 ENST00000359415.4 ENST00000534182.2 ENST00000264028.4	ARCN1	archain 1
chr3_-_10362725	0.40	ENST00000397109.3 ENST00000428626.1 ENST00000445064.1 ENST00000431352.1 ENST00000397117.1 ENST00000337354.4 ENST00000383801.2 ENST00000432213.1 ENST00000350697.3	SEC13	SEC13 homolog (S. cerevisiae)
chr21_-_18985230	0.39	ENST00000457956.1 ENST00000348354.6	BTG3	BTG family, member 3
chr4_+_190992087	0.35	ENST00000553598.1	DUX4L7	double homeobox 4 like 7
chr10_+_112257596	0.35	ENST00000369583.3	DUSP5	dual specificity phosphatase 5
chr8_-_124054362	0.34	ENST00000405944.3	DERL1	derlin 1
chr1_+_207669573	0.31	ENST00000400960.2 ENST00000534202.1	CR1	complement component (3b/4b) receptor 1 (Knops blood group)
chr3_-_105588231	0.31	ENST00000545639.1 ENST00000394027.3 ENST00000438603.1 ENST00000447441.1 ENST00000443752.1	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr2_+_27255806	0.31	ENST00000238788.9 ENST00000404032.3	TMEM214	transmembrane protein 214
chr18_-_34408693	0.30	ENST00000587382.1 ENST00000589049.1 ENST00000587129.1	TPGS2	tubulin polyglutamylase complex subunit 2
chr8_+_105235572	0.29	ENST00000523362.1	RIMS2	regulating synaptic membrane exocytosis 2
chr8_+_67624653	0.28	ENST00000521198.2	SGK3	serum/glucocorticoid regulated kinase family, member 3
chr12_-_109125285	0.27	ENST00000552871.1 ENST00000261401.3	CORO1C	coronin, actin binding protein, 1C
chr19_+_17186577	0.26	ENST00000595618.1 ENST00000594824.1	MYO9B	myosin IXB
chr19_-_4670345	0.26	ENST00000599630.1 ENST00000262947.3	C19orf10	chromosome 19 open reading frame 10
chr19_-_54619006	0.26	ENST00000391759.1	TFPT	TCF3 (E2A) fusion partner (in childhood Leukemia)
chr5_+_126853301	0.25	ENST00000296666.8 ENST00000442138.2 ENST00000512635.2	PRRC1	proline-rich coiled-coil 1
chr19_+_50353944	0.24	ENST00000594151.1 ENST00000600603.1 ENST00000601638.1 ENST00000221557.9	PTOV1	prostate tumor overexpressed 1
chr11_+_64851666	0.23	ENST00000525509.1 ENST00000294258.3 ENST00000526334.1	ZFPL1	zinc finger protein-like 1
chr10_+_104678032	0.22	ENST00000369878.4 ENST00000369875.3	CNNM2	cyclin M2
chr4_+_26322409	0.22	ENST00000514807.1 ENST00000348160.4 ENST00000509158.1 ENST00000355476.3	RBPJ	recombination signal binding protein for immunoglobulin kappa J region
chr1_-_144932316	0.22	ENST00000313431.9	PDE4DIP	phosphodiesterase 4D interacting protein
chrX_-_41782249	0.21	ENST00000442742.2 ENST00000421587.2 ENST00000378166.4 ENST00000318588.9 ENST00000361962.4	CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chrX_+_153059608	0.21	ENST00000370087.1	SSR4	signal sequence receptor, delta
chr12_+_99038919	0.20	ENST00000551964.1	APAF1	apoptotic peptidase activating factor 1
chr3_-_105587879	0.18	ENST00000264122.4 ENST00000403724.1 ENST00000405772.1	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr20_+_57267669	0.16	ENST00000356091.6	NPEPL1	aminopeptidase-like 1
chr20_-_8000426	0.15	ENST00000527925.1 ENST00000246024.2	TMX4	thioredoxin-related transmembrane protein 4
chr19_+_50354393	0.15	ENST00000391842.1	PTOV1	prostate tumor overexpressed 1
chr11_-_59383617	0.15	ENST00000263847.1	OSBP	oxysterol binding protein
chr1_+_207669613	0.14	ENST00000367049.4 ENST00000529814.1	CR1	complement component (3b/4b) receptor 1 (Knops blood group)
chr19_-_19030157	0.13	ENST00000349893.4 ENST00000351079.4 ENST00000600932.1 ENST00000262812.4	COPE	coatomer protein complex, subunit epsilon
chr19_-_54618650	0.12	ENST00000391757.1	TFPT	TCF3 (E2A) fusion partner (in childhood Leukemia)
chr8_-_124054484	0.11	ENST00000419562.2	DERL1	derlin 1
chr4_+_76649797	0.09	ENST00000538159.1 ENST00000514213.2	USO1	USO1 vesicle transport factor
chr19_+_47104493	0.06	ENST00000291295.9 ENST00000597743.1	CALM3	calmodulin 3 (phosphorylase kinase, delta)
chr9_-_35732362	0.05	ENST00000314888.9 ENST00000540444.1	TLN1	talin 1
chr3_+_132378741	0.04	ENST00000493720.2	UBA5	ubiquitin-like modifier activating enzyme 5
chr13_+_26042960	0.04	ENST00000255283.8	ATP8A2	ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr21_-_18985158	0.04	ENST00000339775.6	BTG3	BTG family, member 3
chr22_-_20850128	0.04	ENST00000328879.4	KLHL22	kelch-like family member 22
chr3_-_128369643	0.04	ENST00000296255.3	RPN1	ribophorin I
chr11_-_64646086	0.03	ENST00000320631.3	EHD1	EH-domain containing 1
chr1_-_45988542	0.03	ENST00000424390.1	PRDX1	peroxiredoxin 1
chr11_-_62414070	0.00	ENST00000540933.1 ENST00000346178.4 ENST00000356638.3 ENST00000534779.1 ENST00000525994.1	GANAB	glucosidase, alpha; neutral AB

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	21.0	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.2	5.8	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.8	2.3	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.6	7.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.5	1.6	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.5	1.5	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.4	2.9	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.4	1.1	GO:0002079	inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.3	4.1	GO:0097227	sperm annulus(GO:0097227)
0.3	1.5	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.2	2.4	GO:0030126	COPI vesicle coat(GO:0030126)
0.2	2.7	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.2	4.6	GO:0042599	lamellar body(GO:0042599)
0.2	2.4	GO:1990023	mitotic spindle midzone(GO:1990023)
0.2	3.5	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	0.9	GO:1990037	Lewy body core(GO:1990037)
0.1	0.8	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.1	0.7	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	4.3	GO:0000421	autophagosome membrane(GO:0000421)
0.1	2.0	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	3.1	GO:0042101	T cell receptor complex(GO:0042101)
0.1	3.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	5.4	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1	0.3	GO:0036502	Derlin-1-VIMP complex(GO:0036502)
0.1	0.6	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1	7.7	GO:0043195	terminal bouton(GO:0043195)
0.1	6.3	GO:0005581	collagen trimer(GO:0005581)
0.1	9.8	GO:0032587	ruffle membrane(GO:0032587)
0.1	3.2	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	0.9	GO:0005652	nuclear lamina(GO:0005652)
0.0	2.5	GO:0005801	cis-Golgi network(GO:0005801)
0.0	1.6	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.9	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	1.8	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.3	GO:0016600	flotillin complex(GO:0016600)
0.0	0.4	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0	2.2	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	1.3	GO:0005802	trans-Golgi network(GO:0005802)
0.0	1.4	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	9.4	GO:0000139	Golgi membrane(GO:0000139)
0.0	4.7	GO:0030016	myofibril(GO:0030016)
0.0	0.7	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.0	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	2.5	GO:0005788	endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	21.0	NABA COLLAGENS	Genes encoding collagen proteins
0.3	5.4	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.3	3.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.1	7.7	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	1.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	3.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.1	4.1	PID CDC42 PATHWAY	CDC42 signaling events
0.1	4.0	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	1.9	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	1.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	9.8	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.1	2.0	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	8.1	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.9	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.7	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	5.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.5	PID CD40 PATHWAY	CD40/CD40L signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	21.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.3	7.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.3	6.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.2	7.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	10.1	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	2.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	3.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	2.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.8	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	1.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.7	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	1.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	9.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	1.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	1.5	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	1.9	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	1.2	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	1.1	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	1.8	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	2.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.8	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.9	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.8	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	3.1	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	2.3	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	1.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	2.0	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.8	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	1.2	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.9	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.5	7.4	GO:0004020	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.9	21.0	GO:0048407	platelet-derived growth factor binding(GO:0048407)
1.1	8.6	GO:0046923	ER retention sequence binding(GO:0046923)
1.0	5.8	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.8	2.4	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.6	2.5	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.5	1.5	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.4	6.3	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.4	9.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3	1.0	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.3	1.0	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.3	1.8	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.3	1.2	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.3	1.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2	1.5	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.2	9.1	GO:0003785	actin monomer binding(GO:0003785)
0.2	5.4	GO:0070064	proline-rich region binding(GO:0070064)
0.2	0.7	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.2	0.9	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2	0.5	GO:0001861	complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.1	3.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.1	0.8	GO:0019776	Atg8 ligase activity(GO:0019776)
0.1	2.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	1.9	GO:0035497	cAMP response element binding(GO:0035497)
0.1	2.0	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1	0.6	GO:0008312	7S RNA binding(GO:0008312)
0.1	0.9	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	2.3	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	0.9	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.1	3.3	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	0.7	GO:0000150	recombinase activity(GO:0000150)
0.1	1.7	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	0.9	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	1.3	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.7	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.5	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.0	1.7	GO:0043022	ribosome binding(GO:0043022)
0.0	2.9	GO:0008276	protein methyltransferase activity(GO:0008276)
0.0	1.4	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.3	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.6	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.3	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.3	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.2	GO:0008142	oxysterol binding(GO:0008142)
0.0	2.0	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	2.0	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.3	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	6.4	GO:0045296	cadherin binding(GO:0045296)
0.0	0.8	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	8.4	GO:0005509	calcium ion binding(GO:0005509)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	5.8	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
1.9	7.4	GO:0000103	sulfate assimilation(GO:0000103)
1.4	21.0	GO:0043589	skin morphogenesis(GO:0043589)
1.1	3.3	GO:2000276	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
1.1	3.3	GO:0060535	trachea cartilage morphogenesis(GO:0060535)
0.9	9.8	GO:0031584	activation of phospholipase D activity(GO:0031584) apical protein localization(GO:0045176)
0.8	8.6	GO:0006621	protein retention in ER lumen(GO:0006621)
0.7	2.2	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.6	7.7	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.5	6.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.5	1.5	GO:0071529	cementum mineralization(GO:0071529)
0.5	5.4	GO:0033327	Leydig cell differentiation(GO:0033327)
0.5	1.4	GO:1901873	regulation of post-translational protein modification(GO:1901873)
0.4	1.9	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.4	1.8	GO:0006041	glucosamine metabolic process(GO:0006041) glucose 1-phosphate metabolic process(GO:0019255)
0.3	1.7	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.3	0.7	GO:0072507	magnesium ion homeostasis(GO:0010960) divalent inorganic cation homeostasis(GO:0072507)
0.3	1.0	GO:2000705	histone H3-T6 phosphorylation(GO:0035408) dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.3	3.1	GO:1902284	axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.3	1.1	GO:1903778	protein localization to vacuolar membrane(GO:1903778)
0.3	3.9	GO:0045793	positive regulation of cell size(GO:0045793)
0.3	2.3	GO:0008090	retrograde axonal transport(GO:0008090)
0.3	1.5	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.2	0.7	GO:0060844	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.2	0.9	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2	0.6	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.2	2.7	GO:0035826	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.2	3.1	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.2	2.5	GO:0048843	positive regulation of axon extension involved in axon guidance(GO:0048842) negative regulation of axon extension involved in axon guidance(GO:0048843)
0.2	0.9	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.2	1.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.2	1.7	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.2	0.5	GO:0030451	regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.1	1.0	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1	1.1	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1	2.3	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.1	0.4	GO:0021691	cerebellar Purkinje cell layer maturation(GO:0021691)
0.1	2.4	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.1	0.7	GO:0032472	Golgi calcium ion transport(GO:0032472)
0.1	1.1	GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.1	1.9	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.1	1.6	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.1	0.5	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.1	1.3	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1	0.9	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	0.9	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1	0.3	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.5	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	2.4	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.3	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	2.0	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.8	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.8	GO:0044804	nucleophagy(GO:0044804)
0.0	3.3	GO:0036498	IRE1-mediated unfolded protein response(GO:0036498)
0.0	2.0	GO:0007405	neuroblast proliferation(GO:0007405)
0.0	0.3	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0	4.1	GO:0007224	smoothened signaling pathway(GO:0007224)
0.0	0.3	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.0	2.0	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	10.7	GO:0043687	post-translational protein modification(GO:0043687)
0.0	0.0	GO:0003011	involuntary skeletal muscle contraction(GO:0003011)
0.0	1.4	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.7	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.0	0.6	GO:0007616	long-term memory(GO:0007616)
0.0	0.6	GO:0007155	cell adhesion(GO:0007155) biological adhesion(GO:0022610)
0.0	0.6	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	2.9	GO:0006479	protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0	0.7	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	3.1	GO:0001649	osteoblast differentiation(GO:0001649)
0.0	0.6	GO:0050885	neuromuscular process controlling balance(GO:0050885)