Project

ENCODE cell lines, expression (Ernst 2011)

Navigation
Downloads

Results for ZBTB3

Z-value: 0.43

Motif logo

logo of

Transcription factors associated with ZBTB3

Gene Symbol Gene ID Gene Info
ZBTB3
ENSG00000185670.7 ZBTB3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB3hg19_v2_chr11_-_62521614_625216600.351.9e-01Click!

Activity profile of ZBTB3 motif

Sorted Z-values of ZBTB3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr3_-_149688655 1.40 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
 PFN2
 profilin 2
chr3_-_149688502 1.35 ENST00000481767.1
ENST00000475518.1
 PFN2
 profilin 2
chr4_-_15939963 1.33 ENST00000259988.2
 FGFBP1
 fibroblast growth factor binding protein 1
chr12_-_52887034 1.31 ENST00000330722.6
 KRT6A
 keratin 6A
chr3_-_149688896 1.19 ENST00000239940.7
 PFN2
 profilin 2
chr19_+_16187085 0.86 ENST00000300933.4
 TPM4
 tropomyosin 4
chr2_+_202899310 0.79 ENST00000286201.1
 FZD7
 frizzled family receptor 7
chr5_-_82969405 0.74 ENST00000510978.1
 HAPLN1
 hyaluronan and proteoglycan link protein 1
chr18_-_33709268 0.50 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
 SLC39A6
 solute carrier family 39 (zinc transporter), member 6
chr19_-_49496557 0.46 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
 GYS1
 glycogen synthase 1 (muscle)
chrX_+_134166333 0.42 ENST00000257013.7
 FAM127A
 family with sequence similarity 127, member A
chr7_+_134576317 0.35 ENST00000424922.1
ENST00000495522.1
 CALD1
 caldesmon 1
chr14_-_92414055 0.32 ENST00000342058.4
 FBLN5
 fibulin 5
chr11_-_130786400 0.31 ENST00000265909.4
 SNX19
 sorting nexin 19
chr7_+_134576151 0.31 ENST00000393118.2
 CALD1
 caldesmon 1
chr9_-_34637718 0.31 ENST00000378892.1
ENST00000277010.4
 SIGMAR1
 sigma non-opioid intracellular receptor 1
chr12_-_10022735 0.29 ENST00000228438.2
 CLEC2B
 C-type lectin domain family 2, member B
chr17_-_10325261 0.29 ENST00000403437.2
 MYH8
 myosin, heavy chain 8, skeletal muscle, perinatal
chr13_+_27998681 0.26 ENST00000381140.4
 GTF3A
 general transcription factor IIIA
chr5_+_115177178 0.25 ENST00000316788.7
 AP3S1
 adaptor-related protein complex 3, sigma 1 subunit
chrX_+_23801280 0.22 ENST00000379251.3
ENST00000379253.3
ENST00000379254.1
ENST00000379270.4
 SAT1
 spermidine/spermine N1-acetyltransferase 1
chr14_-_92413353 0.22 ENST00000556154.1
 FBLN5
 fibulin 5
chr10_-_118032979 0.21 ENST00000355422.6
 GFRA1
 GDNF family receptor alpha 1
chr11_+_64692143 0.16 ENST00000164133.2
ENST00000532850.1
 PPP2R5B
 protein phosphatase 2, regulatory subunit B', beta
chr4_-_5894777 0.16 ENST00000324989.7
 CRMP1
 collapsin response mediator protein 1
chr17_+_7531281 0.15 ENST00000575729.1
ENST00000340624.5
 SHBG
 sex hormone-binding globulin
chr4_-_73935409 0.15 ENST00000507544.2
ENST00000295890.4
 COX18
 COX18 cytochrome C oxidase assembly factor
chr3_-_49131473 0.15 ENST00000430979.1
ENST00000357496.2
ENST00000437939.1
 QRICH1
 glutamine-rich 1
chr9_+_74526384 0.14 ENST00000334731.2
ENST00000377031.3
 C9orf85
 chromosome 9 open reading frame 85
chrX_+_152224766 0.14 ENST00000370265.4
ENST00000447306.1
 PNMA3
 paraneoplastic Ma antigen 3
chr18_+_32073253 0.13 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
 DTNA
 dystrobrevin, alpha
chrX_+_118708493 0.13 ENST00000371558.2
 UBE2A
 ubiquitin-conjugating enzyme E2A
chr3_-_49131013 0.12 ENST00000424300.1
 QRICH1
 glutamine-rich 1
chr3_-_49131788 0.11 ENST00000395443.2
ENST00000411682.1
 QRICH1
 glutamine-rich 1
chr6_+_30850697 0.10 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
 DDR1
 discoidin domain receptor tyrosine kinase 1
chr14_-_92413727 0.10 ENST00000267620.10
 FBLN5
 fibulin 5
chr3_-_195163803 0.09 ENST00000326793.6
 ACAP2
 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr9_+_125132803 0.09 ENST00000540753.1
 PTGS1
 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr5_+_170288856 0.08 ENST00000523189.1
 RANBP17
 RAN binding protein 17
chr11_-_18548426 0.08 ENST00000357193.3
ENST00000536719.1
 TSG101
 tumor susceptibility 101
chr1_-_111148969 0.08 ENST00000316361.4
 KCNA2
 potassium voltage-gated channel, shaker-related subfamily, member 2
chr3_+_98250743 0.08 ENST00000284311.3
 GPR15
 G protein-coupled receptor 15
chr21_-_48024986 0.07 ENST00000291700.4
ENST00000367071.4
 S100B
 S100 calcium binding protein B
chr14_-_106725723 0.07 ENST00000390609.2
 IGHV3-23
 immunoglobulin heavy variable 3-23
chr19_-_2042065 0.07 ENST00000591588.1
ENST00000591142.1
 MKNK2
 MAP kinase interacting serine/threonine kinase 2
chr14_+_60715928 0.06 ENST00000395076.4
 PPM1A
 protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr1_-_149908710 0.06 ENST00000439741.2
ENST00000361405.6
ENST00000406732.3
 MTMR11
 myotubularin related protein 11
chr5_+_76506706 0.05 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
 PDE8B
 phosphodiesterase 8B
chr12_+_54718904 0.05 ENST00000262061.2
ENST00000549043.1
ENST00000552218.1
ENST00000553231.1
ENST00000552362.1
ENST00000455864.2
ENST00000416254.2
ENST00000549116.1
ENST00000551779.1
 COPZ1
 coatomer protein complex, subunit zeta 1
chr10_+_99332198 0.04 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
 ANKRD2
 ankyrin repeat domain 2 (stretch responsive muscle)
chr20_+_54987168 0.04 ENST00000360314.3
 CASS4
 Cas scaffolding protein family member 4
chr2_-_136594740 0.03 ENST00000264162.2
 LCT
 lactase
chr8_+_22424551 0.03 ENST00000523348.1
 SORBS3
 sorbin and SH3 domain containing 3
chr20_+_54987305 0.03 ENST00000371336.3
ENST00000434344.1
 CASS4
 Cas scaffolding protein family member 4
chr1_+_160160346 0.03 ENST00000368078.3
 CASQ1
 calsequestrin 1 (fast-twitch, skeletal muscle)
chr5_+_74807886 0.03 ENST00000514296.1
 POLK
 polymerase (DNA directed) kappa
chr12_-_114843889 0.03 ENST00000405440.2
 TBX5
 T-box 5
chr7_-_127225620 0.02 ENST00000321407.2
 GCC1
 GRIP and coiled-coil domain containing 1
chrX_+_118708517 0.02 ENST00000346330.3
 UBE2A
 ubiquitin-conjugating enzyme E2A
chr11_-_82782861 0.02 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
 RAB30
 RAB30, member RAS oncogene family
chr1_+_159141397 0.02 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
 CADM3
 cell adhesion molecule 3
chr11_-_82782952 0.01 ENST00000534141.1
 RAB30
 RAB30, member RAS oncogene family
chr19_-_40023450 0.01 ENST00000326282.4
 EID2B
 EP300 interacting inhibitor of differentiation 2B
chr5_+_140514782 0.01 ENST00000231134.5
 PCDHB5
 protocadherin beta 5
chr10_+_50817141 0.01 ENST00000339797.1
 CHAT
 choline O-acetyltransferase
chr2_-_74570520 0.01 ENST00000394019.2
ENST00000346834.4
ENST00000359484.4
ENST00000423644.1
ENST00000377634.4
ENST00000436454.1
 SLC4A5
 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
chr17_+_72983674 0.00 ENST00000337231.5
 CDR2L
 cerebellar degeneration-related protein 2-like
chr3_-_39322728 0.00 ENST00000541347.1
ENST00000412814.1
 CX3CR1
 chemokine (C-X3-C motif) receptor 1

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.3 4.5 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.2 2.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 3.0 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 2.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.2 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 2.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 2.7 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1 3.0 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 2.0 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 4.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 1.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 5.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 0.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 0.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.9 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 2.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.8 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 2.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.9 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0071953 elastic fiber(GO:0071953)
0.0 0.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 3.9 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 1.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0031417 NatC complex(GO:0031417)
0.6 6.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.6 2.3 GO:1990423 RZZ complex(GO:1990423)
0.6 5.7 GO:0000796 condensin complex(GO:0000796)
0.5 3.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.5 2.9 GO:0030893 meiotic cohesin complex(GO:0030893)
0.4 1.1 GO:0030689 Noc complex(GO:0030689)
0.4 1.1 GO:0034455 t-UTP complex(GO:0034455)
0.3 1.7 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.3 0.9 GO:0043291 RAVE complex(GO:0043291)
0.3 2.0 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.3 1.7 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.3 1.0 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2 1.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2 0.9 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 0.6 GO:1990130 Iml1 complex(GO:1990130)
0.2 3.5 GO:0034709 methylosome(GO:0034709)
0.2 0.9 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 0.9 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 0.5 GO:0031213 RSF complex(GO:0031213)
0.2 0.7 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.2 1.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 1.7 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.6 GO:0032021 NELF complex(GO:0032021)
0.1 2.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.8 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.0 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 2.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 0.5 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.4 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 1.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 2.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 2.8 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.4 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.2 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.5 GO:0019815 B cell receptor complex(GO:0019815)
0.1 12.5 GO:0000922 spindle pole(GO:0000922)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.1 0.7 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 0.4 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 1.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.5 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.1 0.3 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.1 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.3 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.3 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 1.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 1.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 1.2 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 1.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.4 GO:0005840 ribosome(GO:0005840)
0.0 0.8 GO:0046930 pore complex(GO:0046930)
0.0 1.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.3 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.2 GO:0031201 SNARE complex(GO:0031201)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.7 GO:0030686 90S preribosome(GO:0030686)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 2.3 GO:0016234 inclusion body(GO:0016234)
0.0 1.0 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 8.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 6.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.9 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.2 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0097440 apical dendrite(GO:0097440)
0.0 2.3 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.5 GO:0043679 axon terminus(GO:0043679)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.0 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.7 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.1 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 1.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.0 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.6 2.5 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.5 6.0 GO:0051525 NFAT protein binding(GO:0051525)
0.5 1.6 GO:0030350 iron-responsive element binding(GO:0030350)
0.5 2.6 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.5 2.6 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.4 3.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4 3.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.4 6.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.3 1.7 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.3 0.7 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.3 1.2 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.3 0.9 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.3 2.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.3 1.7 GO:0030492 hemoglobin binding(GO:0030492)
0.3 1.1 GO:0043515 kinetochore binding(GO:0043515)
0.3 1.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.3 0.8 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.3 1.0 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 0.8 GO:0050421 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.2 1.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 2.5 GO:0033592 RNA strand annealing activity(GO:0033592)
0.2 0.7 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.2 0.9 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 0.9 GO:0004074 biliverdin reductase activity(GO:0004074)
0.2 0.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 3.0 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.2 0.5 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.2 0.5 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.2 0.5 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 0.5 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.2 0.7 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.2 0.5 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.2 0.5 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 0.4 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 1.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.3 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.1 0.4 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.4 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.5 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.4 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 0.4 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 1.4 GO:0089720 caspase binding(GO:0089720)
0.1 1.7 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.7 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 1.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.4 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.9 GO:0015288 porin activity(GO:0015288)
0.1 3.1 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 0.4 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.3 GO:0016731 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 0.6 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.7 GO:0050733 RS domain binding(GO:0050733)
0.1 0.5 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.6 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.1 0.5 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.3 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.3 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.4 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.5 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 1.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.3 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 0.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 1.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.3 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.5 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.7 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.9 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.3 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.1 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.9 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 1.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.8 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.2 GO:0017089 glycolipid transporter activity(GO:0017089) ceramide binding(GO:0097001)
0.1 0.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.2 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 1.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.4 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.4 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 1.0 GO:0005521 lamin binding(GO:0005521)
0.0 0.9 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 2.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.0 GO:0005123 death receptor binding(GO:0005123)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.9 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.7 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.6 GO:0070628 proteasome binding(GO:0070628)
0.0 0.5 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.1 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.0 0.8 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 1.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 1.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.8 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 3.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 1.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.5 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 0.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.9 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.1 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0043199 sulfate binding(GO:0043199)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.7 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 2.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.0 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 1.7 PID IL5 PATHWAY IL5-mediated signaling events
0.1 4.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 5.0 PID AURORA B PATHWAY Aurora B signaling
0.1 0.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 4.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.9 PID MYC PATHWAY C-MYC pathway
0.0 4.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 2.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 0.9 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.4 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
1.1 3.3 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
1.0 3.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.6 3.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.6 2.4 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.5 3.2 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.5 2.5 GO:0042256 mature ribosome assembly(GO:0042256)
0.5 2.7 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.4 2.6 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.4 1.1 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.4 2.9 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.4 1.1 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.4 2.1 GO:0015853 adenine transport(GO:0015853)
0.3 1.0 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.3 0.9 GO:0035283 rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.3 1.2 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.3 0.9 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.3 2.0 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.3 4.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.3 0.8 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.2 0.7 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.2 0.9 GO:0006272 leading strand elongation(GO:0006272)
0.2 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 0.7 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.2 0.7 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 2.4 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.2 2.6 GO:0006108 malate metabolic process(GO:0006108)
0.2 0.4 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.2 2.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 1.7 GO:0006552 leucine catabolic process(GO:0006552)
0.2 0.7 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.2 0.5 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.2 0.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 1.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.2 0.5 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.2 2.1 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.2 0.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 0.8 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.2 0.8 GO:0051182 coenzyme transport(GO:0051182)
0.2 0.5 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.1 0.9 GO:0018343 protein farnesylation(GO:0018343)
0.1 2.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 0.4 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.4 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.7 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.5 GO:0042223 response to molecule of fungal origin(GO:0002238) regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226)
0.1 0.4 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 1.7 GO:0015671 oxygen transport(GO:0015671)
0.1 1.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.7 GO:0035900 response to isolation stress(GO:0035900)
0.1 0.4 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 1.2 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.5 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 6.7 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.1 0.8 GO:1904044 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
0.1 1.0 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 0.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.4 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.4 GO:1903405 protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.1 0.3 GO:0072134 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133) nephrogenic mesenchyme morphogenesis(GO:0072134)
0.1 0.3 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.3 GO:0048382 mesendoderm development(GO:0048382)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.5 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.4 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 1.4 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 1.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 1.2 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1 0.5 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 0.3 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.1 0.5 GO:1902775 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.7 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.2 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 0.5 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.1 0.3 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.4 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1 0.5 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) regulation of receptor catabolic process(GO:2000644)
0.1 0.3 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.4 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 0.5 GO:0033504 floor plate development(GO:0033504)
0.1 2.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 1.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.2 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.1 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.9 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.2 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 0.2 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 0.4 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 0.2 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.1 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 2.7 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 0.5 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.1 0.8 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.4 GO:0072642 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1 0.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 0.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.5 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.1 1.6 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 0.5 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.1 0.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.6 GO:0015791 polyol transport(GO:0015791)
0.1 0.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.2 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 1.4 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 0.9 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.4 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.1 0.4 GO:1901419 regulation of response to alcohol(GO:1901419)
0.1 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.4 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 1.7 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.5 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 1.4 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.9 GO:0002021 response to dietary excess(GO:0002021)
0.1 0.2 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.1 0.1 GO:0015966 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.1 0.7 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.1 0.9 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.5 GO:0006983 ER overload response(GO:0006983)
0.0 0.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.5 GO:0033227 dsRNA transport(GO:0033227)
0.0 1.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 1.0 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.5 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.5 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.5 GO:0015886 heme transport(GO:0015886)
0.0 0.5 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.5 GO:0007030 Golgi organization(GO:0007030)
0.0 0.1 GO:0045905 translational frameshifting(GO:0006452) peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.4 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.6 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 1.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0 0.5 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 1.2 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.5 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 2.8 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.2 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.2 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289) regulation of Golgi inheritance(GO:0090170)
0.0 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0048667 cell morphogenesis involved in neuron differentiation(GO:0048667)
0.0 0.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 2.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.7 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.5 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.3 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.3 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.3 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.3 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 1.9 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 1.6 GO:0043069 negative regulation of apoptotic process(GO:0043066) negative regulation of programmed cell death(GO:0043069)
0.0 0.1 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.5 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0 1.5 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.6 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.5 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.5 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.5 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 3.1 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 1.5 GO:0060416 response to growth hormone(GO:0060416)
0.0 0.5 GO:0051181 cofactor transport(GO:0051181)
0.0 1.0 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 1.1 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0010046 response to mycotoxin(GO:0010046)
0.0 0.9 GO:0048538 thymus development(GO:0048538)
0.0 0.6 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.3 GO:0016051 carbohydrate biosynthetic process(GO:0016051)
0.0 0.5 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498)
0.0 0.3 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.6 GO:0035909 aorta morphogenesis(GO:0035909)
0.0 0.1 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.0 0.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.3 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.3 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.0 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.3 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.3 GO:0051607 defense response to virus(GO:0051607)
0.0 0.1 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.7 GO:0006400 tRNA modification(GO:0006400)
0.0 0.8 GO:0005977 glycogen metabolic process(GO:0005977)
0.0 0.1 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0001505 regulation of neurotransmitter levels(GO:0001505)
0.0 0.2 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.3 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.1 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.2 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.0 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.2 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.3 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.0 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 0.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.0 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
0.3 3.9 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.3 0.8 GO:0009996 negative regulation of cell fate specification(GO:0009996)
0.2 1.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.3 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.2 GO:0009447 putrescine catabolic process(GO:0009447)
0.1 0.2 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.1 0.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:2000395 ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:0072678 T cell migration(GO:0072678)
0.0 1.1 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.2 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)