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ENCODE cell lines, expression (Ernst 2011)

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Results for ZIC3_ZIC4

Z-value: 1.10

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Transcription factors associated with ZIC3_ZIC4

Gene Symbol Gene ID Gene Info
ZIC3
ENSG00000156925.7 ZIC3
ZIC4
ENSG00000174963.13 ZIC4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZIC3hg19_v2_chrX_+_136648297_1366483190.146.2e-01Click!

Activity profile of ZIC3_ZIC4 motif

Sorted Z-values of ZIC3_ZIC4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC3_ZIC4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_32801825 3.68 ENST00000329421.7
 MARCKSL1
 MARCKS-like 1
chr14_+_31343747 2.59 ENST00000216361.4
ENST00000396618.3
ENST00000475087.1
 COCH
 cochlin
chr5_+_75699149 2.54 ENST00000379730.3
 IQGAP2
 IQ motif containing GTPase activating protein 2
chr16_-_88717482 2.47 ENST00000261623.3
 CYBA
 cytochrome b-245, alpha polypeptide
chr5_+_75699040 2.36 ENST00000274364.6
 IQGAP2
 IQ motif containing GTPase activating protein 2
chr20_+_34203794 2.13 ENST00000374273.3
 SPAG4
 sperm associated antigen 4
chr4_-_40631859 1.76 ENST00000295971.7
ENST00000319592.4
 RBM47
 RNA binding motif protein 47
chr20_+_35201857 1.32 ENST00000373874.2
 TGIF2
 TGFB-induced factor homeobox 2
chr20_+_35201993 1.19 ENST00000373872.4
 TGIF2
 TGFB-induced factor homeobox 2
chr9_-_130742792 1.08 ENST00000373095.1
 FAM102A
 family with sequence similarity 102, member A
chrX_-_78622805 1.07 ENST00000373298.2
 ITM2A
 integral membrane protein 2A
chr11_-_78128811 0.92 ENST00000530915.1
ENST00000361507.4
 GAB2
 GRB2-associated binding protein 2
chr1_-_114355083 0.89 ENST00000261441.5
 RSBN1
 round spermatid basic protein 1
chr7_+_149571045 0.88 ENST00000479613.1
ENST00000606024.1
ENST00000464662.1
ENST00000425642.2
 ATP6V0E2
 ATPase, H+ transporting V0 subunit e2
chr7_-_994302 0.78 ENST00000265846.5
 ADAP1
 ArfGAP with dual PH domains 1
chr5_+_121647877 0.78 ENST00000514497.2
ENST00000261367.7
 SNCAIP
 synuclein, alpha interacting protein
chr17_-_38721711 0.77 ENST00000578085.1
ENST00000246657.2
 CCR7
 chemokine (C-C motif) receptor 7
chr11_+_22688150 0.76 ENST00000454584.2
 GAS2
 growth arrest-specific 2
chr5_+_121647764 0.74 ENST00000261368.8
ENST00000379533.2
ENST00000379536.2
ENST00000379538.3
 SNCAIP
 synuclein, alpha interacting protein
chr16_-_58231782 0.72 ENST00000565188.1
ENST00000262506.3
 CSNK2A2
 casein kinase 2, alpha prime polypeptide
chr3_-_17783990 0.71 ENST00000429383.4
ENST00000446863.1
ENST00000414349.1
ENST00000428355.1
ENST00000425944.1
ENST00000445294.1
ENST00000444471.1
ENST00000415814.2
 TBC1D5
 TBC1 domain family, member 5
chr12_-_48398104 0.70 ENST00000337299.6
ENST00000380518.3
 COL2A1
 collagen, type II, alpha 1
chr15_+_75074385 0.69 ENST00000220003.9
 CSK
 c-src tyrosine kinase
chr7_+_99775366 0.69 ENST00000394018.2
ENST00000416412.1
 STAG3
 stromal antigen 3
chr15_+_75074410 0.69 ENST00000439220.2
 CSK
 c-src tyrosine kinase
chr6_-_29595779 0.66 ENST00000355973.3
ENST00000377012.4
 GABBR1
 gamma-aminobutyric acid (GABA) B receptor, 1
chr7_+_99775520 0.65 ENST00000317296.5
ENST00000422690.1
ENST00000439782.1
 STAG3
 stromal antigen 3
chr10_+_21823079 0.61 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
 MLLT10
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr10_+_35416223 0.60 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
 CREM
 cAMP responsive element modulator
chr5_+_137688285 0.60 ENST00000314358.5
 KDM3B
 lysine (K)-specific demethylase 3B
chr16_+_2039946 0.60 ENST00000248121.2
ENST00000568896.1
 SYNGR3
 synaptogyrin 3
chr22_+_23134974 0.59 ENST00000390314.2
 IGLV2-11
 immunoglobulin lambda variable 2-11
chr4_+_154387480 0.58 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
 KIAA0922
 KIAA0922
chr13_+_35516390 0.58 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
 NBEA
 neurobeachin
chr11_+_33563821 0.57 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
 KIAA1549L
 KIAA1549-like
chr19_-_48753104 0.55 ENST00000447740.2
 CARD8
 caspase recruitment domain family, member 8
chr1_-_25256368 0.55 ENST00000308873.6
 RUNX3
 runt-related transcription factor 3
chr5_+_121647924 0.54 ENST00000414317.2
 SNCAIP
 synuclein, alpha interacting protein
chr11_-_73694346 0.54 ENST00000310473.3
 UCP2
 uncoupling protein 2 (mitochondrial, proton carrier)
chr17_-_40428359 0.54 ENST00000293328.3
 STAT5B
 signal transducer and activator of transcription 5B
chr14_-_21994525 0.53 ENST00000538754.1
 SALL2
 spalt-like transcription factor 2
chr19_-_48752812 0.53 ENST00000359009.4
 CARD8
 caspase recruitment domain family, member 8
chr7_-_105925558 0.53 ENST00000222553.3
 NAMPT
 nicotinamide phosphoribosyltransferase
chr11_-_407103 0.52 ENST00000526395.1
 SIGIRR
 single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr22_-_20368028 0.50 ENST00000404912.1
 GGTLC3
 gamma-glutamyltransferase light chain 3
chr2_+_8822113 0.50 ENST00000396290.1
ENST00000331129.3
 ID2
 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr1_-_212873267 0.48 ENST00000243440.1
 BATF3
 basic leucine zipper transcription factor, ATF-like 3
chr7_+_150758304 0.46 ENST00000482950.1
ENST00000463414.1
ENST00000310317.5
 SLC4A2
 solute carrier family 4 (anion exchanger), member 2
chr15_-_70388599 0.46 ENST00000560996.1
ENST00000558201.1
 TLE3
 transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr22_-_47134077 0.46 ENST00000541677.1
ENST00000216264.8
 CERK
 ceramide kinase
chr9_-_98279241 0.46 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
 PTCH1
 patched 1
chr10_+_21823243 0.43 ENST00000307729.7
ENST00000377091.2
 MLLT10
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr5_+_169064245 0.43 ENST00000256935.8
 DOCK2
 dedicator of cytokinesis 2
chr3_-_129035120 0.43 ENST00000333762.4
 H1FX
 H1 histone family, member X
chr2_+_128180842 0.42 ENST00000402125.2
 PROC
 protein C (inactivator of coagulation factors Va and VIIIa)
chr5_-_151304337 0.42 ENST00000455880.2
ENST00000545569.1
ENST00000274576.4
 GLRA1
 glycine receptor, alpha 1
chr20_-_62680984 0.42 ENST00000340356.7
 SOX18
 SRY (sex determining region Y)-box 18
chr9_+_4490394 0.41 ENST00000262352.3
 SLC1A1
 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr1_-_55680762 0.41 ENST00000407756.1
ENST00000294383.6
 USP24
 ubiquitin specific peptidase 24
chr1_+_52195542 0.41 ENST00000462759.1
ENST00000486942.1
 OSBPL9
 oxysterol binding protein-like 9
chr16_+_67596310 0.40 ENST00000264010.4
ENST00000401394.1
 CTCF
 CCCTC-binding factor (zinc finger protein)
chr17_-_4890649 0.40 ENST00000361571.5
 CAMTA2
 calmodulin binding transcription activator 2
chrX_-_151903184 0.39 ENST00000357916.4
ENST00000393869.3
 MAGEA12
 melanoma antigen family A, 12
chr17_-_5026397 0.38 ENST00000250076.3
 ZNF232
 zinc finger protein 232
chr12_-_51785182 0.38 ENST00000356317.3
ENST00000603188.1
ENST00000604847.1
ENST00000604506.1
 GALNT6
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr1_-_38273840 0.38 ENST00000373044.2
 YRDC
 yrdC N(6)-threonylcarbamoyltransferase domain containing
chr5_-_111091948 0.38 ENST00000447165.2
 NREP
 neuronal regeneration related protein
chr17_+_38599693 0.38 ENST00000542955.1
ENST00000269593.4
 IGFBP4
 insulin-like growth factor binding protein 4
chr1_+_52195480 0.38 ENST00000531828.1
ENST00000361556.5
ENST00000481937.1
 OSBPL9
 oxysterol binding protein-like 9
chr8_-_27462822 0.37 ENST00000522098.1
 CLU
 clusterin
chr9_-_124989804 0.37 ENST00000373755.2
ENST00000373754.2
 LHX6
 LIM homeobox 6
chr17_-_76124812 0.37 ENST00000592063.1
ENST00000589271.1
ENST00000322933.4
ENST00000589553.1
 TMC6
 transmembrane channel-like 6
chr22_+_19467261 0.37 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
 CDC45
 cell division cycle 45
chr19_+_45409011 0.36 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
 APOE
 apolipoprotein E
chr15_-_69113218 0.36 ENST00000560303.1
ENST00000465139.2
 ANP32A
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr4_-_57301748 0.36 ENST00000264220.2
 PPAT
 phosphoribosyl pyrophosphate amidotransferase
chr16_+_30205754 0.35 ENST00000354723.6
ENST00000355544.5
 SULT1A3
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr16_-_1993260 0.35 ENST00000361871.3
 MSRB1
 methionine sulfoxide reductase B1
chr8_-_70745575 0.34 ENST00000524945.1
 SLCO5A1
 solute carrier organic anion transporter family, member 5A1
chr7_-_44924939 0.34 ENST00000395699.2
 PURB
 purine-rich element binding protein B
chr4_-_140098339 0.33 ENST00000394235.2
 ELF2
 E74-like factor 2 (ets domain transcription factor)
chr2_-_96811170 0.33 ENST00000288943.4
 DUSP2
 dual specificity phosphatase 2
chr17_-_39191107 0.33 ENST00000344363.5
 KRTAP1-3
 keratin associated protein 1-3
chr8_+_90770008 0.32 ENST00000540020.1
 RIPK2
 receptor-interacting serine-threonine kinase 2
chr6_+_134274322 0.32 ENST00000367871.1
ENST00000237264.4
 TBPL1
 TBP-like 1
chr9_+_134269439 0.32 ENST00000405995.1
 PRRC2B
 proline-rich coiled-coil 2B
chrX_+_23352133 0.31 ENST00000379361.4
 PTCHD1
 patched domain containing 1
chr6_+_36410762 0.31 ENST00000483557.1
ENST00000498267.1
ENST00000544295.1
ENST00000449081.2
ENST00000536244.1
ENST00000460983.1
 KCTD20
 potassium channel tetramerization domain containing 20
chr1_+_3370990 0.31 ENST00000378378.4
 ARHGEF16
 Rho guanine nucleotide exchange factor (GEF) 16
chrX_-_131352152 0.31 ENST00000342983.2
 RAP2C
 RAP2C, member of RAS oncogene family
chr2_+_65216462 0.31 ENST00000234256.3
 SLC1A4
 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr5_-_37835010 0.30 ENST00000510177.1
 GDNF
 glial cell derived neurotrophic factor
chr11_-_60719213 0.30 ENST00000227880.3
 SLC15A3
 solute carrier family 15 (oligopeptide transporter), member 3
chr3_-_50540854 0.30 ENST00000423994.2
ENST00000424201.2
ENST00000479441.1
ENST00000429770.1
 CACNA2D2
 calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr3_+_184097836 0.30 ENST00000204604.1
ENST00000310236.3
 CHRD
 chordin
chrX_+_41192595 0.30 ENST00000399959.2
 DDX3X
 DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr17_-_78194147 0.29 ENST00000534910.1
ENST00000326317.6
 SGSH
 N-sulfoglucosamine sulfohydrolase
chr11_-_64510409 0.29 ENST00000394429.1
ENST00000394428.1
 RASGRP2
 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr22_+_19466980 0.29 ENST00000407835.1
ENST00000438587.1
 CDC45
 cell division cycle 45
chr14_+_103243813 0.29 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
 TRAF3
 TNF receptor-associated factor 3
chr19_+_5823813 0.29 ENST00000303212.2
 NRTN
 neurturin
chr3_-_194991876 0.29 ENST00000310380.6
 XXYLT1
 xyloside xylosyltransferase 1
chr11_+_64781575 0.28 ENST00000246747.4
ENST00000529384.1
 ARL2
 ADP-ribosylation factor-like 2
chr11_+_64781657 0.28 ENST00000533729.1
 ARL2
 ADP-ribosylation factor-like 2
chr22_-_26986045 0.28 ENST00000442495.1
ENST00000440953.1
ENST00000450022.1
ENST00000338754.4
 TPST2
 tyrosylprotein sulfotransferase 2
chr3_+_184097905 0.28 ENST00000450923.1
 CHRD
 chordin
chr2_+_10183651 0.27 ENST00000305883.1
 KLF11
 Kruppel-like factor 11
chr17_-_41738931 0.27 ENST00000329168.3
ENST00000549132.1
 MEOX1
 mesenchyme homeobox 1
chr10_+_88854926 0.27 ENST00000298784.1
ENST00000298786.4
 FAM35A
 family with sequence similarity 35, member A
chr5_+_102455968 0.27 ENST00000358359.3
 PPIP5K2
 diphosphoinositol pentakisphosphate kinase 2
chr8_+_90769967 0.26 ENST00000220751.4
 RIPK2
 receptor-interacting serine-threonine kinase 2
chr7_+_128577972 0.26 ENST00000357234.5
ENST00000477535.1
ENST00000479582.1
ENST00000464557.1
ENST00000402030.2
 IRF5
 interferon regulatory factor 5
chr6_+_143857949 0.26 ENST00000367584.4
 PHACTR2
 phosphatase and actin regulator 2
chr12_-_51419924 0.25 ENST00000541174.2
 SLC11A2
 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr16_+_29818857 0.25 ENST00000567444.1
 MAZ
 MYC-associated zinc finger protein (purine-binding transcription factor)
chr17_-_4890919 0.25 ENST00000572543.1
ENST00000381311.5
ENST00000348066.3
ENST00000358183.4
 CAMTA2
 calmodulin binding transcription activator 2
chr22_+_22735135 0.24 ENST00000390297.2
 IGLV1-44
 immunoglobulin lambda variable 1-44
chr21_+_45285050 0.24 ENST00000291572.8
 AGPAT3
 1-acylglycerol-3-phosphate O-acyltransferase 3
chrX_+_123095155 0.24 ENST00000371160.1
ENST00000435103.1
 STAG2
 stromal antigen 2
chr19_-_50063907 0.24 ENST00000598296.1
 NOSIP
 nitric oxide synthase interacting protein
chr4_-_149363662 0.24 ENST00000355292.3
ENST00000358102.3
 NR3C2
 nuclear receptor subfamily 3, group C, member 2
chrX_+_24711997 0.23 ENST00000379068.3
ENST00000379059.3
 POLA1
 polymerase (DNA directed), alpha 1, catalytic subunit
chr6_+_89791507 0.23 ENST00000354922.3
 PNRC1
 proline-rich nuclear receptor coactivator 1
chr9_+_100745615 0.23 ENST00000339399.4
 ANP32B
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr9_-_88356789 0.23 ENST00000357081.3
ENST00000376081.4
ENST00000337006.4
ENST00000376109.3
 AGTPBP1
 ATP/GTP binding protein 1
chr20_+_3869423 0.23 ENST00000497424.1
 PANK2
 pantothenate kinase 2
chr9_+_100174232 0.23 ENST00000355295.4
 TDRD7
 tudor domain containing 7
chr8_+_67976593 0.23 ENST00000262210.5
ENST00000412460.1
 CSPP1
 centrosome and spindle pole associated protein 1
chrX_-_130423386 0.22 ENST00000370903.3
 IGSF1
 immunoglobulin superfamily, member 1
chr20_+_3870024 0.22 ENST00000610179.1
 PANK2
 pantothenate kinase 2
chr2_+_134877740 0.22 ENST00000409645.1
 MGAT5
 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr14_-_64971288 0.22 ENST00000394715.1
 ZBTB25
 zinc finger and BTB domain containing 25
chr9_-_34662651 0.22 ENST00000259631.4
 CCL27
 chemokine (C-C motif) ligand 27
chr12_+_121163538 0.22 ENST00000242592.4
 ACADS
 acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr10_+_127408263 0.22 ENST00000337623.3
 C10orf137
 erythroid differentiation regulatory factor 1
chr1_-_161147275 0.22 ENST00000319769.5
ENST00000367998.1
 B4GALT3
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr16_+_2570340 0.22 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
 AMDHD2
 amidohydrolase domain containing 2
chr10_-_105212141 0.21 ENST00000369788.3
 CALHM2
 calcium homeostasis modulator 2
chr2_+_74781828 0.21 ENST00000340004.6
 DOK1
 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr7_-_140178726 0.21 ENST00000480552.1
 MKRN1
 makorin ring finger protein 1
chrX_-_130423240 0.21 ENST00000370910.1
ENST00000370901.4
 IGSF1
 immunoglobulin superfamily, member 1
chr15_-_66790146 0.21 ENST00000316634.5
 SNAPC5
 small nuclear RNA activating complex, polypeptide 5, 19kDa
chr3_+_38495333 0.21 ENST00000352511.4
 ACVR2B
 activin A receptor, type IIB
chr12_-_48213568 0.21 ENST00000080059.7
ENST00000354334.3
ENST00000430670.1
ENST00000552960.1
ENST00000440293.1
 HDAC7
 histone deacetylase 7
chr19_+_59055814 0.21 ENST00000594806.1
ENST00000253024.5
ENST00000341753.6
 TRIM28
 tripartite motif containing 28
chr14_+_24641062 0.21 ENST00000311457.3
ENST00000557806.1
ENST00000559919.1
 REC8
 REC8 meiotic recombination protein
chr2_+_79740118 0.21 ENST00000496558.1
ENST00000451966.1
 CTNNA2
 catenin (cadherin-associated protein), alpha 2
chr14_+_105886150 0.21 ENST00000331320.7
ENST00000406191.1
 MTA1
 metastasis associated 1
chr12_-_51420108 0.21 ENST00000547198.1
 SLC11A2
 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr20_-_62129163 0.20 ENST00000298049.7
 EEF1A2
 eukaryotic translation elongation factor 1 alpha 2
chr4_+_115519577 0.20 ENST00000310836.6
 UGT8
 UDP glycosyltransferase 8
chr3_-_9811595 0.20 ENST00000256460.3
 CAMK1
 calcium/calmodulin-dependent protein kinase I
chr2_-_11484710 0.20 ENST00000315872.6
 ROCK2
 Rho-associated, coiled-coil containing protein kinase 2
chr10_+_14920843 0.20 ENST00000433779.1
ENST00000378325.3
ENST00000354919.6
ENST00000313519.5
ENST00000420416.1
 SUV39H2
 suppressor of variegation 3-9 homolog 2 (Drosophila)
chr4_+_2819883 0.20 ENST00000511747.1
ENST00000503393.2
 SH3BP2
 SH3-domain binding protein 2
chr11_-_57004658 0.20 ENST00000606794.1
 APLNR
 apelin receptor
chr12_-_48152853 0.19 ENST00000171000.4
 RAPGEF3
 Rap guanine nucleotide exchange factor (GEF) 3
chr16_+_58497567 0.19 ENST00000258187.5
 NDRG4
 NDRG family member 4
chr14_-_95942173 0.19 ENST00000334258.5
ENST00000557275.1
ENST00000553340.1
 SYNE3
 spectrin repeat containing, nuclear envelope family member 3
chr19_+_10362882 0.19 ENST00000393733.2
ENST00000588502.1
 MRPL4
 mitochondrial ribosomal protein L4
chr1_+_3607228 0.19 ENST00000378285.1
ENST00000378280.1
ENST00000378288.4
 TP73
 tumor protein p73
chr13_-_41345277 0.18 ENST00000323563.6
 MRPS31
 mitochondrial ribosomal protein S31
chr20_-_62601218 0.18 ENST00000369888.1
 ZNF512B
 zinc finger protein 512B
chr4_-_121993673 0.18 ENST00000379692.4
 NDNF
 neuron-derived neurotrophic factor
chr1_+_28995231 0.18 ENST00000373816.1
 GMEB1
 glucocorticoid modulatory element binding protein 1
chr3_+_38179969 0.18 ENST00000396334.3
ENST00000417037.2
ENST00000424893.1
ENST00000495303.1
ENST00000443433.2
ENST00000421516.1
 MYD88
 myeloid differentiation primary response 88
chrX_+_51927919 0.18 ENST00000416960.1
 MAGED4
 melanoma antigen family D, 4
chr6_+_44238203 0.18 ENST00000451188.2
 TMEM151B
 transmembrane protein 151B
chr14_+_91580357 0.18 ENST00000298858.4
ENST00000521081.1
ENST00000520328.1
ENST00000256324.10
ENST00000524232.1
ENST00000522170.1
ENST00000519950.1
ENST00000523879.1
ENST00000521077.2
ENST00000518665.2
 C14orf159
 chromosome 14 open reading frame 159
chr14_+_91580708 0.18 ENST00000518868.1
 C14orf159
 chromosome 14 open reading frame 159
chr19_-_12992244 0.18 ENST00000538460.1
 DNASE2
 deoxyribonuclease II, lysosomal
chr6_+_15246501 0.18 ENST00000341776.2
 JARID2
 jumonji, AT rich interactive domain 2
chr15_-_91565770 0.18 ENST00000535906.1
ENST00000333371.3
 VPS33B
 vacuolar protein sorting 33 homolog B (yeast)
chr4_-_168155169 0.17 ENST00000534949.1
ENST00000535728.1
 SPOCK3
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr16_+_58059470 0.17 ENST00000219271.3
 MMP15
 matrix metallopeptidase 15 (membrane-inserted)
chr19_+_589893 0.17 ENST00000251287.2
 HCN2
 hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr17_-_4871085 0.17 ENST00000575142.1
ENST00000206020.3
 SPAG7
 sperm associated antigen 7
chr21_+_45725050 0.17 ENST00000403390.1
 PFKL
 phosphofructokinase, liver
chr12_-_12503156 0.17 ENST00000543314.1
ENST00000396349.3
 MANSC1
 MANSC domain containing 1
chr1_+_114471809 0.17 ENST00000426820.2
 HIPK1
 homeodomain interacting protein kinase 1
chr4_+_81951957 0.17 ENST00000282701.2
 BMP3
 bone morphogenetic protein 3
chr10_-_105212059 0.17 ENST00000260743.5
 CALHM2
 calcium homeostasis modulator 2
chr7_+_150020329 0.17 ENST00000323078.7
 LRRC61
 leucine rich repeat containing 61
chr2_+_48757278 0.17 ENST00000404752.1
ENST00000406226.1
 STON1
 stonin 1
chr12_-_121734489 0.17 ENST00000412367.2
ENST00000402834.4
ENST00000404169.3
 CAMKK2
 calcium/calmodulin-dependent protein kinase kinase 2, beta
chr1_+_146714291 0.17 ENST00000431239.1
ENST00000369259.3
ENST00000369258.4
ENST00000361293.5
 CHD1L
 chromodomain helicase DNA binding protein 1-like
chr19_-_49314269 0.17 ENST00000545387.2
ENST00000316273.6
ENST00000402551.1
ENST00000598162.1
ENST00000599246.1
 BCAT2
 branched chain amino-acid transaminase 2, mitochondrial
chr7_+_73498118 0.17 ENST00000336180.2
 LIMK1
 LIM domain kinase 1
chr16_+_29465822 0.16 ENST00000330181.5
ENST00000351581.4
 SLX1B
 SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr9_-_140351928 0.16 ENST00000339554.3
 NSMF
 NMDA receptor synaptonuclear signaling and neuronal migration factor
chr14_+_91580777 0.16 ENST00000525393.2
ENST00000428926.2
ENST00000517362.1
 C14orf159
 chromosome 14 open reading frame 159
chrX_-_153881842 0.16 ENST00000369585.3
ENST00000247306.4
 CTAG2
 cancer/testis antigen 2
chrX_+_123094672 0.16 ENST00000354548.5
ENST00000458700.1
 STAG2
 stromal antigen 2
chr11_+_47291193 0.16 ENST00000428807.1
ENST00000402799.1
ENST00000406482.1
ENST00000349238.3
ENST00000311027.5
ENST00000407859.3
ENST00000395344.3
ENST00000444117.1
 MADD
 MAP-kinase activating death domain
chr1_+_28995258 0.16 ENST00000361872.4
ENST00000294409.2
 GMEB1
 glucocorticoid modulatory element binding protein 1
chr2_-_64881018 0.16 ENST00000313349.3
 SERTAD2
 SERTA domain containing 2
chr22_-_31328881 0.15 ENST00000445980.1
 MORC2
 MORC family CW-type zinc finger 2
chr17_-_73178599 0.15 ENST00000578238.1
 SUMO2
 small ubiquitin-like modifier 2
chr22_+_19705928 0.15 ENST00000383045.3
ENST00000438754.2
 SEPT5
 septin 5
chr3_-_194090460 0.15 ENST00000428839.1
ENST00000347624.3
 LRRC15
 leucine rich repeat containing 15

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0030893 meiotic cohesin complex(GO:0030893)
0.2 0.7 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.2 0.6 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 2.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 5.0 GO:0031941 filamentous actin(GO:0031941)
0.1 1.1 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.9 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.7 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.5 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 2.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 2.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 1.0 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.6 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0031970 organelle envelope lumen(GO:0031970)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0031092 platelet alpha granule membrane(GO:0031092)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 2.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.5 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 3.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.3 1.8 GO:0016554 cytidine to uridine editing(GO:0016554)
0.3 1.4 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.3 1.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.3 0.8 GO:2000525 dendritic cell dendrite assembly(GO:0097026) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.2 0.7 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.2 4.9 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 0.7 GO:0031938 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 2.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 2.5 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.6 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.1 0.4 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 0.8 GO:0006549 isoleucine metabolic process(GO:0006549)
0.1 0.4 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.5 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.4 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.1 0.4 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.1 0.5 GO:0021997 response to chlorate(GO:0010157) neural plate axis specification(GO:0021997)
0.1 1.1 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1 0.3 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 1.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 0.7 GO:0000101 sulfur amino acid transport(GO:0000101)
0.1 0.3 GO:0061056 sclerotome development(GO:0061056)
0.1 0.4 GO:0048865 stem cell fate commitment(GO:0048865)
0.1 2.6 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.4 GO:0015692 lead ion transport(GO:0015692)
0.1 0.3 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.1 0.3 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 0.5 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.2 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.1 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.4 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.2 GO:1901535 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) regulation of genetic imprinting(GO:2000653)
0.1 0.1 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.1 0.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.6 GO:0072718 response to cisplatin(GO:0072718)
0.1 0.7 GO:0060174 limb bud formation(GO:0060174)
0.1 0.3 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.3 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 0.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.1 GO:0002572 pro-T cell differentiation(GO:0002572)
0.1 0.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.4 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.4 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188) histone H3-K27 demethylation(GO:0071557)
0.0 0.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.9 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.5 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 1.3 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.5 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.2 GO:0048617 embryonic foregut morphogenesis(GO:0048617)
0.0 0.4 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.3 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.4 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.1 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.0 0.1 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.0 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 0.1 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.5 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.2 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.5 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.1 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.0 0.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.9 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.2 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.0 GO:0055073 cadmium ion homeostasis(GO:0055073)
0.0 0.1 GO:2000229 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.1 GO:0021913 glandular epithelial cell maturation(GO:0002071) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) type B pancreatic cell maturation(GO:0072560)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0035802 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802) posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.2 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.1 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.2 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.7 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.7 GO:0097421 liver regeneration(GO:0097421)
0.0 0.1 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.6 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.4 GO:0044342 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) type B pancreatic cell proliferation(GO:0044342)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.7 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 0.1 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.2 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.2 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.0 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.2 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.0 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.0 0.0 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.2 GO:0060627 regulation of vesicle-mediated transport(GO:0060627)
0.0 0.1 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0015870 acetylcholine transport(GO:0015870)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0060326 cell chemotaxis(GO:0060326)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.0 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 1.0 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.1 GO:0061047 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 3.1 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.0 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.0 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.0 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.1 GO:0042756 drinking behavior(GO:0042756)
0.0 0.0 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.1 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.2 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.4 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.1 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 2.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME P75NTR SIGNALS VIA NFKB Genes involved in p75NTR signals via NF-kB
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 2.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.6 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.4 1.1 GO:0032089 NACHT domain binding(GO:0032089)
0.2 0.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 0.5 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.7 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.7 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 2.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.4 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.8 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.5 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 2.1 GO:0043495 protein anchor(GO:0043495)
0.1 0.3 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 0.7 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.4 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.7 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.4 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.2 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 1.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.4 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.3 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.4 GO:0034711 inhibin binding(GO:0034711)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.4 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.9 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 2.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0042578 phosphoric ester hydrolase activity(GO:0042578)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 3.6 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0045309 phosphotyrosine binding(GO:0001784) protein phosphorylated amino acid binding(GO:0045309)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)