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ENCODE cell lines, expression (Ernst 2011)

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Results for ZNF274

Z-value: 0.53

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Transcription factors associated with ZNF274

Gene Symbol Gene ID Gene Info
ZNF274
ENSG00000171606.13 ZNF274

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF274hg19_v2_chr19_+_58694396_586944850.116.8e-01Click!

Activity profile of ZNF274 motif

Sorted Z-values of ZNF274 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF274

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_+_40195101 1.41 ENST00000360675.3
ENST00000601802.1
 LGALS14
 lectin, galactoside-binding, soluble, 14
chr19_+_40194946 1.39 ENST00000392052.3
 LGALS14
 lectin, galactoside-binding, soluble, 14
chr1_-_114414316 0.80 ENST00000528414.1
ENST00000538253.1
ENST00000460620.1
ENST00000420377.2
ENST00000525799.1
ENST00000359785.5
 PTPN22
 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr19_+_6887571 0.74 ENST00000250572.8
ENST00000381407.5
ENST00000312053.4
ENST00000450315.3
ENST00000381404.4
 EMR1
 egf-like module containing, mucin-like, hormone receptor-like 1
chr1_+_45205478 0.69 ENST00000452259.1
ENST00000372224.4
 KIF2C
 kinesin family member 2C
chr2_-_89292422 0.68 ENST00000495489.1
 IGKV1-8
 immunoglobulin kappa variable 1-8
chr12_+_113344755 0.68 ENST00000550883.1
 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr1_+_45205498 0.66 ENST00000372218.4
 KIF2C
 kinesin family member 2C
chr6_-_32784687 0.61 ENST00000447394.1
ENST00000438763.2
 HLA-DOB
 major histocompatibility complex, class II, DO beta
chr18_+_9103957 0.58 ENST00000400033.1
 NDUFV2
 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr16_+_29819096 0.52 ENST00000568411.1
ENST00000563012.1
ENST00000562557.1
 MAZ
 MYC-associated zinc finger protein (purine-binding transcription factor)
chr16_+_29819446 0.49 ENST00000568282.1
 MAZ
 MYC-associated zinc finger protein (purine-binding transcription factor)
chr16_+_29819372 0.48 ENST00000568544.1
ENST00000569978.1
 MAZ
 MYC-associated zinc finger protein (purine-binding transcription factor)
chr12_-_54653313 0.43 ENST00000550411.1
ENST00000439541.2
 CBX5
 chromobox homolog 5
chr10_+_5488564 0.42 ENST00000449083.1
ENST00000380359.3
 NET1
 neuroepithelial cell transforming 1
chr16_+_29818857 0.42 ENST00000567444.1
 MAZ
 MYC-associated zinc finger protein (purine-binding transcription factor)
chr5_+_32531893 0.36 ENST00000512913.1
 SUB1
 SUB1 homolog (S. cerevisiae)
chr17_-_41132410 0.35 ENST00000409446.3
ENST00000453594.1
ENST00000409399.1
ENST00000421990.2
 PTGES3L
PTGES3L-AARSD1
 prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chrX_+_119737806 0.31 ENST00000371317.5
 MCTS1
 malignant T cell amplified sequence 1
chr2_-_96971259 0.28 ENST00000349783.5
 SNRNP200
 small nuclear ribonucleoprotein 200kDa (U5)
chr6_+_30687978 0.25 ENST00000327892.8
ENST00000435534.1
 TUBB
 tubulin, beta class I
chr11_-_10590118 0.23 ENST00000529598.1
 LYVE1
 lymphatic vessel endothelial hyaluronan receptor 1
chr4_-_121993673 0.22 ENST00000379692.4
 NDNF
 neuron-derived neurotrophic factor
chr11_+_16760161 0.19 ENST00000524439.1
ENST00000422258.2
ENST00000528634.1
ENST00000525684.1
 C11orf58
 chromosome 11 open reading frame 58
chr15_+_89164520 0.15 ENST00000332810.3
 AEN
 apoptosis enhancing nuclease
chr19_-_19774473 0.13 ENST00000357324.6
 ATP13A1
 ATPase type 13A1
chr17_+_41132564 0.11 ENST00000361677.1
ENST00000589705.1
 RUNDC1
 RUN domain containing 1
chr2_+_11864458 0.11 ENST00000396098.1
ENST00000396099.1
ENST00000425416.2
 LPIN1
 lipin 1
chr6_+_31553978 0.09 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
 LST1
 leukocyte specific transcript 1
chr6_+_31553901 0.07 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
 LST1
 leukocyte specific transcript 1
chr19_+_6135646 0.06 ENST00000588304.1
ENST00000588485.1
ENST00000588722.1
ENST00000591403.1
ENST00000586696.1
ENST00000589401.1
ENST00000252669.5
 ACSBG2
 acyl-CoA synthetase bubblegum family member 2
chr5_-_74162605 0.04 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
 FAM169A
 family with sequence similarity 169, member A
chr17_-_3461092 0.04 ENST00000301365.4
ENST00000572519.1
 TRPV3
 transient receptor potential cation channel, subfamily V, member 3
chr2_+_159313452 0.03 ENST00000389757.3
ENST00000389759.3
 PKP4
 plakophilin 4
chr7_-_73038822 0.02 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
 MLXIPL
 MLX interacting protein-like
chr22_-_43036607 0.01 ENST00000505920.1
 ATP5L2
 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.6 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.2 0.6 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.2 2.8 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.1 1.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.3 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 0.4 GO:0051451 myoblast migration(GO:0051451)
0.0 1.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 1.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID AURORA B PATHWAY Aurora B signaling
0.0 2.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation