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ENCODE cell lines, expression (Ernst 2011)

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Results for ZNF282

Z-value: 0.44

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Transcription factors associated with ZNF282

Gene Symbol Gene ID Gene Info
ZNF282
ENSG00000170265.7 ZNF282

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF282hg19_v2_chr7_+_148892557_148892580-0.401.3e-01Click!

Activity profile of ZNF282 motif

Sorted Z-values of ZNF282 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF282

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_169753156 0.89 ENST00000393726.3
ENST00000507735.1
 PALLD
 palladin, cytoskeletal associated protein
chr6_+_106959718 0.81 ENST00000369066.3
 AIM1
 absent in melanoma 1
chrX_-_13835147 0.58 ENST00000493677.1
ENST00000355135.2
 GPM6B
 glycoprotein M6B
chr17_+_42422662 0.52 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
 GRN
 granulin
chr17_+_42422637 0.51 ENST00000053867.3
ENST00000588143.1
 GRN
 granulin
chr20_+_18269121 0.46 ENST00000377671.3
ENST00000360010.5
ENST00000396026.3
ENST00000402618.2
ENST00000401790.1
ENST00000434018.1
ENST00000538547.1
ENST00000535822.1
 ZNF133
 zinc finger protein 133
chr22_+_45898712 0.44 ENST00000455233.1
ENST00000348697.2
ENST00000402984.3
ENST00000262722.7
ENST00000327858.6
ENST00000442170.2
ENST00000340923.5
ENST00000439835.1
 FBLN1
 fibulin 1
chr6_+_129204337 0.44 ENST00000421865.2
 LAMA2
 laminin, alpha 2
chr12_-_122296755 0.41 ENST00000289004.4
 HPD
 4-hydroxyphenylpyruvate dioxygenase
chr17_+_7942335 0.37 ENST00000380183.4
ENST00000572022.1
ENST00000380173.2
 ALOX15B
 arachidonate 15-lipoxygenase, type B
chr14_+_55590646 0.33 ENST00000553493.1
 LGALS3
 lectin, galactoside-binding, soluble, 3
chr10_+_114135004 0.32 ENST00000393081.1
 ACSL5
 acyl-CoA synthetase long-chain family member 5
chr1_+_2004901 0.30 ENST00000400921.2
 PRKCZ
 protein kinase C, zeta
chrX_-_13835461 0.30 ENST00000316715.4
ENST00000356942.5
 GPM6B
 glycoprotein M6B
chr21_+_35747773 0.29 ENST00000399292.3
ENST00000399299.1
ENST00000399295.2
 SMIM11
 small integral membrane protein 11
chr17_+_66509019 0.27 ENST00000585981.1
ENST00000589480.1
ENST00000585815.1
 PRKAR1A
 protein kinase, cAMP-dependent, regulatory, type I, alpha
chr2_+_219283815 0.24 ENST00000248444.5
ENST00000454069.1
ENST00000392114.2
 VIL1
 villin 1
chr1_+_35247859 0.22 ENST00000373362.3
 GJB3
 gap junction protein, beta 3, 31kDa
chr8_-_23261589 0.22 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
 LOXL2
 lysyl oxidase-like 2
chr4_-_153457197 0.22 ENST00000281708.4
 FBXW7
 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr16_+_67204400 0.22 ENST00000563439.1
ENST00000432069.2
ENST00000564992.1
ENST00000564053.1
 NOL3
 nucleolar protein 3 (apoptosis repressor with CARD domain)
chr13_+_31309645 0.22 ENST00000380490.3
 ALOX5AP
 arachidonate 5-lipoxygenase-activating protein
chr11_+_66278080 0.22 ENST00000318312.7
ENST00000526815.1
ENST00000537537.1
ENST00000525809.1
ENST00000455748.2
ENST00000393994.2
 BBS1
 Bardet-Biedl syndrome 1
chr2_+_242289502 0.21 ENST00000451310.1
 SEPT2
 septin 2
chr19_-_39390440 0.21 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
 SIRT2
 sirtuin 2
chr9_+_126777676 0.20 ENST00000488674.2
 LHX2
 LIM homeobox 2
chr1_+_2005425 0.20 ENST00000461106.2
 PRKCZ
 protein kinase C, zeta
chr20_-_43150601 0.20 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
 SERINC3
 serine incorporator 3
chr1_-_9129735 0.19 ENST00000377424.4
 SLC2A5
 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr5_+_78365577 0.18 ENST00000518666.1
ENST00000521567.1
 BHMT2
 betaine--homocysteine S-methyltransferase 2
chr1_-_24151892 0.18 ENST00000235958.4
 HMGCL
 3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr1_+_13910479 0.17 ENST00000509009.1
 PDPN
 podoplanin
chr1_+_145507587 0.17 ENST00000330165.8
ENST00000369307.3
 RBM8A
 RNA binding motif protein 8A
chr1_-_24151903 0.17 ENST00000436439.2
ENST00000374490.3
 HMGCL
 3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr1_+_151171012 0.16 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
 PIP5K1A
 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr19_-_39390350 0.16 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
 SIRT2
 sirtuin 2
chr1_-_13390765 0.15 ENST00000357367.2
 PRAMEF8
 PRAME family member 8
chr3_-_106959424 0.15 ENST00000607801.1
ENST00000479612.2
ENST00000484698.1
ENST00000477210.2
ENST00000473636.1
 LINC00882
 long intergenic non-protein coding RNA 882
chr1_+_160313062 0.15 ENST00000294785.5
ENST00000368063.1
ENST00000437169.1
 NCSTN
 nicastrin
chr12_-_46766577 0.15 ENST00000256689.5
 SLC38A2
 solute carrier family 38, member 2
chr1_+_13910757 0.14 ENST00000376061.4
ENST00000513143.1
 PDPN
 podoplanin
chr5_+_175299743 0.12 ENST00000502265.1
 CPLX2
 complexin 2
chr16_+_67927147 0.12 ENST00000291041.5
 PSKH1
 protein serine kinase H1
chr16_-_70239683 0.12 ENST00000601706.1
 AC009060.1
 Uncharacterized protein
chr17_-_77924627 0.11 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
 TBC1D16
 TBC1 domain family, member 16
chr5_+_167718604 0.11 ENST00000265293.4
 WWC1
 WW and C2 domain containing 1
chr10_+_95753714 0.11 ENST00000260766.3
 PLCE1
 phospholipase C, epsilon 1
chr19_-_58220517 0.11 ENST00000512439.2
ENST00000426889.1
 ZNF154
 zinc finger protein 154
chr1_-_9129631 0.11 ENST00000377414.3
 SLC2A5
 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr2_-_9695847 0.10 ENST00000310823.3
ENST00000497134.1
 ADAM17
 ADAM metallopeptidase domain 17
chr6_+_39760783 0.10 ENST00000398904.2
ENST00000538976.1
 DAAM2
 dishevelled associated activator of morphogenesis 2
chr7_+_139025875 0.09 ENST00000297534.6
 C7orf55
 chromosome 7 open reading frame 55
chr18_+_54318566 0.09 ENST00000589935.1
ENST00000357574.3
 WDR7
 WD repeat domain 7
chr1_+_17248418 0.09 ENST00000375541.5
 CROCC
 ciliary rootlet coiled-coil, rootletin
chr19_+_44617511 0.08 ENST00000262894.6
ENST00000588926.1
ENST00000592780.1
 ZNF225
 zinc finger protein 225
chr12_-_9102549 0.08 ENST00000000412.3
 M6PR
 mannose-6-phosphate receptor (cation dependent)
chr15_+_51200871 0.08 ENST00000560508.1
 AP4E1
 adaptor-related protein complex 4, epsilon 1 subunit
chr7_+_16828866 0.08 ENST00000597084.1
 AC073333.1
 Uncharacterized protein
chr5_-_175788758 0.08 ENST00000510164.1
ENST00000533553.1
ENST00000504688.1
ENST00000393725.2
ENST00000503082.1
ENST00000506983.1
 KIAA1191
 KIAA1191
chr5_+_140552218 0.06 ENST00000231137.3
 PCDHB7
 protocadherin beta 7
chr17_+_41323204 0.06 ENST00000542611.1
ENST00000590996.1
ENST00000389312.4
ENST00000589872.1
 NBR1
 neighbor of BRCA1 gene 1
chr15_-_44955842 0.06 ENST00000427534.2
ENST00000559193.1
ENST00000261866.7
ENST00000535302.2
ENST00000558319.1
 SPG11
 spastic paraplegia 11 (autosomal recessive)
chr17_-_56605341 0.06 ENST00000583114.1
 SEPT4
 septin 4
chr19_+_7953384 0.06 ENST00000306708.6
 LRRC8E
 leucine rich repeat containing 8 family, member E
chr2_+_233415363 0.06 ENST00000409514.1
ENST00000409098.1
ENST00000409495.1
ENST00000409167.3
ENST00000409322.1
ENST00000409394.1
 EIF4E2
 eukaryotic translation initiation factor 4E family member 2
chr12_-_13248562 0.05 ENST00000457134.2
ENST00000537302.1
 GSG1
 germ cell associated 1
chr6_+_32938665 0.05 ENST00000374831.4
ENST00000395289.2
 BRD2
 bromodomain containing 2
chr18_-_54318353 0.05 ENST00000590954.1
ENST00000540155.1
 TXNL1
 thioredoxin-like 1
chr9_+_34652164 0.04 ENST00000441545.2
ENST00000553620.1
 IL11RA
 interleukin 11 receptor, alpha
chr17_+_44039704 0.04 ENST00000420682.2
ENST00000415613.2
ENST00000571987.1
ENST00000574436.1
ENST00000431008.3
 MAPT
 microtubule-associated protein tau
chr1_-_155947951 0.04 ENST00000313695.7
ENST00000497907.1
 ARHGEF2
 Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr3_+_45927994 0.04 ENST00000357632.2
ENST00000395963.2
 CCR9
 chemokine (C-C motif) receptor 9
chr6_-_79944336 0.04 ENST00000344726.5
ENST00000275036.7
 HMGN3
 high mobility group nucleosomal binding domain 3
chr14_-_24911448 0.04 ENST00000555355.1
ENST00000553343.1
ENST00000556523.1
ENST00000556249.1
ENST00000538105.2
ENST00000555225.1
 SDR39U1
 short chain dehydrogenase/reductase family 39U, member 1
chr15_+_51200859 0.04 ENST00000261842.5
 AP4E1
 adaptor-related protein complex 4, epsilon 1 subunit
chr1_+_52682052 0.03 ENST00000371591.1
 ZFYVE9
 zinc finger, FYVE domain containing 9
chr12_-_49582978 0.03 ENST00000301071.7
 TUBA1A
 tubulin, alpha 1a
chr12_-_13248598 0.03 ENST00000337630.6
ENST00000545699.1
 GSG1
 germ cell associated 1
chr19_-_46285736 0.03 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
 DMPK
 dystrophia myotonica-protein kinase
chr11_-_66445219 0.03 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
 RBM4B
 RNA binding motif protein 4B
chr16_+_30207122 0.03 ENST00000395137.2
 SULT1A3
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr8_-_27630102 0.02 ENST00000356537.4
ENST00000522915.1
ENST00000539095.1
 CCDC25
 coiled-coil domain containing 25
chr19_-_51340469 0.02 ENST00000326856.4
 KLK15
 kallikrein-related peptidase 15
chr16_+_29467780 0.02 ENST00000395400.3
 SULT1A4
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr11_-_6633799 0.01 ENST00000299424.4
 TAF10
 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr20_-_2451395 0.01 ENST00000339610.6
ENST00000381342.2
ENST00000438552.2
 SNRPB
 small nuclear ribonucleoprotein polypeptides B and B1
chr5_+_65892174 0.01 ENST00000404260.3
ENST00000403625.2
ENST00000406374.1
 MAST4
 microtubule associated serine/threonine kinase family member 4
chr19_+_39390587 0.01 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
 NFKBIB
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr2_-_68479614 0.00 ENST00000234310.3
 PPP3R1
 protein phosphatase 3, regulatory subunit B, alpha
chr19_-_6110474 0.00 ENST00000587181.1
ENST00000587321.1
ENST00000586806.1
ENST00000589742.1
ENST00000592546.1
ENST00000303657.5
 RFX2
 regulatory factor X, 2 (influences HLA class II expression)
chr18_+_54318616 0.00 ENST00000254442.3
 WDR7
 WD repeat domain 7
chr17_-_73389854 0.00 ENST00000578961.1
ENST00000392564.1
ENST00000582582.1
 GRB2
 growth factor receptor-bound protein 2
chr2_+_233415488 0.00 ENST00000454501.1
 EIF4E2
 eukaryotic translation initiation factor 4E family member 2
chr6_+_32938692 0.00 ENST00000443797.2
 BRD2
 bromodomain containing 2
chr6_+_144471643 0.00 ENST00000367568.4
 STX11
 syntaxin 11

Gene Ontology Analysis

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.4 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.4 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.2 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.1 0.2 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.3 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.3 GO:0019863 IgE binding(GO:0019863)
0.0 0.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.5 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase inhibitor activity(GO:0004862) cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.0 GO:0099609 microtubule lateral binding(GO:0099609)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:2000777 positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1 0.3 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.1 0.3 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.9 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.5 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.2 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.1 0.4 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.4 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.3 GO:1990539 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.9 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.1 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.4 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.0 0.3 GO:2000480 negative regulation of meiotic nuclear division(GO:0045835) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.2 GO:0071267 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.0 GO:0071802 negative regulation of podosome assembly(GO:0071802)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0071953 elastic fiber(GO:0071953)
0.0 0.4 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0031588 cAMP-dependent protein kinase complex(GO:0005952) nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.4 GO:0005605 basal lamina(GO:0005605)