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ENCODE cell lines, expression (Ernst 2011)

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Results for ZNF350

Z-value: 0.44

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Transcription factors associated with ZNF350

Gene Symbol Gene ID Gene Info
ZNF350
ENSG00000256683.2 ZNF350

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF350hg19_v2_chr19_-_52489923_52490113-0.504.7e-02Click!

Activity profile of ZNF350 motif

Sorted Z-values of ZNF350 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF350

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr17_-_39674668 1.45 ENST00000393981.3
 KRT15
 keratin 15
chr11_-_112034803 0.74 ENST00000528832.1
 IL18
 interleukin 18 (interferon-gamma-inducing factor)
chr11_-_112034831 0.70 ENST00000280357.7
 IL18
 interleukin 18 (interferon-gamma-inducing factor)
chr11_-_112034780 0.69 ENST00000524595.1
 IL18
 interleukin 18 (interferon-gamma-inducing factor)
chr2_+_235860616 0.59 ENST00000392011.2
 SH3BP4
 SH3-domain binding protein 4
chr20_+_4666882 0.54 ENST00000379440.4
ENST00000430350.2
 PRNP
 prion protein
chr2_-_219157250 0.46 ENST00000434015.2
ENST00000444183.1
ENST00000420341.1
ENST00000453281.1
ENST00000258412.3
ENST00000440422.1
 TMBIM1
 transmembrane BAX inhibitor motif containing 1
chr20_+_4667094 0.41 ENST00000424424.1
ENST00000457586.1
 PRNP
 prion protein
chr20_+_44035847 0.41 ENST00000372712.2
 DBNDD2
 dysbindin (dystrobrevin binding protein 1) domain containing 2
chr4_-_99578789 0.40 ENST00000511651.1
ENST00000505184.1
 TSPAN5
 tetraspanin 5
chr16_+_4526341 0.35 ENST00000458134.3
ENST00000219700.6
ENST00000575120.1
ENST00000572812.1
ENST00000574466.1
ENST00000576827.1
ENST00000570445.1
 HMOX2
 heme oxygenase (decycling) 2
chr12_+_113376157 0.35 ENST00000228928.7
 OAS3
 2'-5'-oligoadenylate synthetase 3, 100kDa
chr4_-_99578776 0.33 ENST00000515287.1
 TSPAN5
 tetraspanin 5
chr20_+_44035200 0.33 ENST00000372717.1
ENST00000360981.4
 DBNDD2
 dysbindin (dystrobrevin binding protein 1) domain containing 2
chr17_-_62340581 0.32 ENST00000258991.3
ENST00000583738.1
ENST00000584379.1
 TEX2
 testis expressed 2
chr3_-_155524049 0.30 ENST00000534941.1
ENST00000340171.2
 C3orf33
 chromosome 3 open reading frame 33
chr11_-_327537 0.30 ENST00000602735.1
 IFITM3
 interferon induced transmembrane protein 3
chr4_-_120133661 0.27 ENST00000503243.1
ENST00000326780.3
 RP11-455G16.1
 Uncharacterized protein
chr2_-_9143786 0.24 ENST00000462696.1
ENST00000305997.3
 MBOAT2
 membrane bound O-acyltransferase domain containing 2
chr14_+_96671016 0.21 ENST00000542454.2
ENST00000554311.1
ENST00000306005.3
ENST00000539359.1
ENST00000553811.1
 BDKRB2
RP11-404P21.8
 bradykinin receptor B2
Uncharacterized protein
chr2_-_21266935 0.21 ENST00000233242.1
 APOB
 apolipoprotein B
chr17_+_48624450 0.21 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
 SPATA20
 spermatogenesis associated 20
chr19_-_5680499 0.16 ENST00000587589.1
 C19orf70
 chromosome 19 open reading frame 70
chr8_-_119124045 0.13 ENST00000378204.2
 EXT1
 exostosin glycosyltransferase 1
chr19_+_35645817 0.11 ENST00000423817.3
 FXYD5
 FXYD domain containing ion transport regulator 5
chr16_+_14802801 0.11 ENST00000526520.1
ENST00000531598.2
 NPIPA3
 nuclear pore complex interacting protein family, member A3
chr19_+_35645618 0.11 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
 FXYD5
 FXYD domain containing ion transport regulator 5
chr12_+_81471816 0.11 ENST00000261206.3
 ACSS3
 acyl-CoA synthetase short-chain family member 3
chr20_-_35374456 0.11 ENST00000373803.2
ENST00000359675.2
ENST00000540765.1
ENST00000349004.1
 NDRG3
 NDRG family member 3
chr2_+_219524379 0.10 ENST00000443791.1
ENST00000359273.3
ENST00000392109.1
ENST00000392110.2
ENST00000423377.1
ENST00000392111.2
ENST00000412366.1
 BCS1L
 BC1 (ubiquinol-cytochrome c reductase) synthesis-like
chr22_-_50964558 0.09 ENST00000535425.1
ENST00000439934.1
 SCO2
 SCO2 cytochrome c oxidase assembly protein
chr11_-_7041466 0.09 ENST00000536068.1
ENST00000278314.4
 ZNF214
 zinc finger protein 214
chr21_-_30365136 0.09 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
 LTN1
 listerin E3 ubiquitin protein ligase 1
chr19_+_2977444 0.08 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
 TLE6
 transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr11_-_69633792 0.08 ENST00000334134.2
 FGF3
 fibroblast growth factor 3
chr3_-_128902729 0.08 ENST00000451728.2
ENST00000446936.2
ENST00000502976.1
ENST00000500450.2
ENST00000441626.2
 CNBP
 CCHC-type zinc finger, nucleic acid binding protein
chr15_+_42694573 0.07 ENST00000397200.4
ENST00000569827.1
 CAPN3
 calpain 3, (p94)
chr1_-_200379180 0.06 ENST00000294740.3
 ZNF281
 zinc finger protein 281
chr11_-_8954491 0.06 ENST00000526227.1
ENST00000525780.1
ENST00000326053.5
 C11orf16
 chromosome 11 open reading frame 16
chr19_+_1450112 0.06 ENST00000590469.1
ENST00000233607.2
ENST00000238483.4
ENST00000590877.1
 APC2
 adenomatosis polyposis coli 2
chr17_-_18950310 0.06 ENST00000573099.1
 GRAP
 GRB2-related adaptor protein
chr2_-_106810783 0.06 ENST00000283148.7
 UXS1
 UDP-glucuronate decarboxylase 1
chr19_-_49243845 0.06 ENST00000222145.4
 RASIP1
 Ras interacting protein 1
chr2_+_219524473 0.06 ENST00000439945.1
ENST00000431802.1
 BCS1L
 BC1 (ubiquinol-cytochrome c reductase) synthesis-like
chr17_-_6554877 0.05 ENST00000225728.3
ENST00000575197.1
 MED31
 mediator complex subunit 31
chr10_+_50822480 0.05 ENST00000455728.2
 CHAT
 choline O-acetyltransferase
chr2_-_70780770 0.05 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
 TGFA
 transforming growth factor, alpha
chr2_-_106810742 0.05 ENST00000409501.3
ENST00000428048.2
ENST00000441952.1
ENST00000457835.1
ENST00000540130.1
 UXS1
 UDP-glucuronate decarboxylase 1
chr8_-_144679296 0.05 ENST00000317198.6
 EEF1D
 eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr11_+_68671310 0.05 ENST00000255078.3
ENST00000539224.1
 IGHMBP2
 immunoglobulin mu binding protein 2
chr1_-_33647267 0.05 ENST00000291416.5
 TRIM62
 tripartite motif containing 62
chrX_-_47479246 0.04 ENST00000295987.7
ENST00000340666.4
 SYN1
 synapsin I
chr1_+_204797749 0.04 ENST00000367172.4
ENST00000367171.4
ENST00000367170.4
ENST00000338515.6
ENST00000339876.6
ENST00000338586.6
ENST00000539706.1
ENST00000360049.4
ENST00000367169.4
ENST00000446412.1
ENST00000403080.1
 NFASC
 neurofascin
chr11_+_8932828 0.04 ENST00000530281.1
ENST00000396648.2
ENST00000534147.1
ENST00000529942.1
 AKIP1
 A kinase (PRKA) interacting protein 1
chr17_-_39597173 0.04 ENST00000246646.3
 KRT38
 keratin 38
chr2_-_70780572 0.03 ENST00000450929.1
 TGFA
 transforming growth factor, alpha
chr1_+_156611960 0.03 ENST00000361588.5
 BCAN
 brevican
chrX_+_120181457 0.03 ENST00000328078.1
 GLUD2
 glutamate dehydrogenase 2
chr1_-_200379129 0.03 ENST00000367353.1
 ZNF281
 zinc finger protein 281
chr11_+_64323428 0.03 ENST00000377581.3
 SLC22A11
 solute carrier family 22 (organic anion/urate transporter), member 11
chr12_-_93323013 0.03 ENST00000322349.8
 EEA1
 early endosome antigen 1
chr16_+_31225337 0.03 ENST00000322122.3
 TRIM72
 tripartite motif containing 72
chr3_-_128902759 0.03 ENST00000422453.2
ENST00000504813.1
ENST00000512338.1
 CNBP
 CCHC-type zinc finger, nucleic acid binding protein
chr6_-_28303901 0.03 ENST00000439158.1
ENST00000446474.1
ENST00000414431.1
ENST00000344279.6
ENST00000453745.1
 ZSCAN31
 zinc finger and SCAN domain containing 31
chr1_-_247094628 0.03 ENST00000366508.1
ENST00000326225.3
ENST00000391829.2
 AHCTF1
 AT hook containing transcription factor 1
chr15_-_43029252 0.03 ENST00000563260.1
ENST00000356231.3
 CDAN1
 codanin 1
chr1_+_63788730 0.03 ENST00000371116.2
 FOXD3
 forkhead box D3
chr17_-_18950950 0.03 ENST00000284154.5
 GRAP
 GRB2-related adaptor protein
chr10_-_15762124 0.03 ENST00000378076.3
 ITGA8
 integrin, alpha 8
chr11_+_8932715 0.03 ENST00000529876.1
ENST00000525005.1
ENST00000524577.1
ENST00000534506.1
 AKIP1
 A kinase (PRKA) interacting protein 1
chr2_+_238600788 0.02 ENST00000289175.6
ENST00000244815.5
 LRRFIP1
 leucine rich repeat (in FLII) interacting protein 1
chr17_-_8093471 0.02 ENST00000389017.4
 C17orf59
 chromosome 17 open reading frame 59
chr1_+_156611704 0.02 ENST00000329117.5
 BCAN
 brevican
chr14_+_73603126 0.02 ENST00000557356.1
ENST00000556864.1
ENST00000556533.1
ENST00000556951.1
ENST00000557293.1
ENST00000553719.1
ENST00000553599.1
ENST00000556011.1
ENST00000394157.3
ENST00000357710.4
ENST00000324501.5
ENST00000560005.2
ENST00000555254.1
ENST00000261970.3
ENST00000344094.3
ENST00000554131.1
ENST00000557037.1
 PSEN1
 presenilin 1
chr10_+_50822083 0.02 ENST00000337653.2
ENST00000395562.2
 CHAT
 choline O-acetyltransferase
chr16_-_46865047 0.01 ENST00000394806.2
 C16orf87
 chromosome 16 open reading frame 87
chr3_-_11623804 0.01 ENST00000451674.2
 VGLL4
 vestigial like 4 (Drosophila)
chr19_+_5681011 0.01 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
 HSD11B1L
 hydroxysteroid (11-beta) dehydrogenase 1-like
chr11_-_64647144 0.01 ENST00000359393.2
ENST00000433803.1
ENST00000411683.1
 EHD1
 EH-domain containing 1
chr2_+_177025619 0.01 ENST00000410016.1
 HOXD3
 homeobox D3
chr10_-_12084770 0.01 ENST00000357604.5
 UPF2
 UPF2 regulator of nonsense transcripts homolog (yeast)
chr7_+_2559399 0.01 ENST00000222725.5
ENST00000359574.3
 LFNG
 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr19_-_4535233 0.01 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
 PLIN5
 perilipin 5
chr10_-_120938303 0.00 ENST00000356951.3
ENST00000298510.2
 PRDX3
 peroxiredoxin 3
chr19_+_49866851 0.00 ENST00000221498.2
ENST00000596402.1
 DKKL1
 dickkopf-like 1
chr1_-_204654481 0.00 ENST00000367176.3
 LRRN2
 leucine rich repeat neuronal 2
chr16_+_67282853 0.00 ENST00000299798.11
 SLC9A5
 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.3 1.0 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.1 0.5 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.1 0.3 GO:0006788 heme oxidation(GO:0006788)
0.1 0.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.3 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.2 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.6 GO:0043090 amino acid import(GO:0043090)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 1.5 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.0 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.0 GO:0097454 Schwann cell microvillus(GO:0097454)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 1.5 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 2.1 REACTOME SIGNALING BY ILS Genes involved in Signaling by Interleukins

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network