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ENCODE cell lines, expression (Ernst 2011)

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Results for ZNF740_ZNF219

Z-value: 1.79

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Transcription factors associated with ZNF740_ZNF219

Gene Symbol Gene ID Gene Info
ENSG00000139651.9 ZNF740
ENSG00000165804.11 ZNF219

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF219hg19_v2_chr14_-_21566731_21566836,
hg19_v2_chr14_-_21567009_21567173
0.087.6e-01Click!

Activity profile of ZNF740_ZNF219 motif

Sorted Z-values of ZNF740_ZNF219 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF740_ZNF219

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_148779106 4.05 ENST00000416719.1
ENST00000264169.2
ORC4
origin recognition complex, subunit 4
chr1_-_150208320 3.93 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr16_+_23847339 3.78 ENST00000303531.7
PRKCB
protein kinase C, beta
chr3_-_171177852 3.58 ENST00000284483.8
ENST00000475336.1
ENST00000357327.5
ENST00000460047.1
ENST00000488470.1
ENST00000470834.1
TNIK
TRAF2 and NCK interacting kinase
chr1_-_150208291 3.51 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr3_-_171178157 3.45 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
TNIK
TRAF2 and NCK interacting kinase
chr11_-_46142948 3.41 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr16_+_23847267 3.41 ENST00000321728.7
PRKCB
protein kinase C, beta
chr1_-_150208363 2.98 ENST00000436748.2
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr6_-_32157947 2.57 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr1_-_150208412 2.39 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr11_-_33891362 2.28 ENST00000395833.3
LMO2
LIM domain only 2 (rhombotin-like 1)
chr20_+_57466629 2.18 ENST00000371081.1
ENST00000338783.6
GNAS
GNAS complex locus
chr17_+_36861735 2.14 ENST00000378137.5
ENST00000325718.7
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr1_+_26856236 2.09 ENST00000374168.2
ENST00000374166.4
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr1_-_150208498 2.06 ENST00000314136.8
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr19_-_36233332 2.06 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
IGFLR1
IGF-like family receptor 1
chr1_+_26737253 2.03 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr1_+_26737292 2.00 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr6_-_34664612 1.86 ENST00000374023.3
ENST00000374026.3
C6orf106
chromosome 6 open reading frame 106
chr14_-_23451467 1.82 ENST00000555074.1
ENST00000361265.4
RP11-298I3.5
AJUBA
RP11-298I3.5
ajuba LIM protein
chr2_-_148778323 1.79 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4
origin recognition complex, subunit 4
chr6_+_42749759 1.78 ENST00000314073.5
GLTSCR1L
GLTSCR1-like
chr2_-_61765315 1.78 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr1_-_111746966 1.75 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr12_-_9913489 1.71 ENST00000228434.3
ENST00000536709.1
CD69
CD69 molecule
chr3_+_5020801 1.66 ENST00000256495.3
BHLHE40
basic helix-loop-helix family, member e40
chr19_-_46476791 1.66 ENST00000263257.5
NOVA2
neuro-oncological ventral antigen 2
chr4_+_154387480 1.64 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
KIAA0922
chr16_+_30675654 1.62 ENST00000287468.5
ENST00000395073.2
FBRS
fibrosin
chr17_-_42276574 1.58 ENST00000589805.1
ATXN7L3
ataxin 7-like 3
chr4_-_140098339 1.52 ENST00000394235.2
ELF2
E74-like factor 2 (ets domain transcription factor)
chr1_-_38273840 1.51 ENST00000373044.2
YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr7_-_150675372 1.46 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr20_-_52210368 1.45 ENST00000371471.2
ZNF217
zinc finger protein 217
chr16_+_29817841 1.39 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr14_-_21493649 1.38 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG2
NDRG family member 2
chr10_+_21823079 1.38 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr2_-_64371546 1.38 ENST00000358912.4
PELI1
pellino E3 ubiquitin protein ligase 1
chr15_-_61521495 1.37 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr15_-_37392086 1.35 ENST00000561208.1
MEIS2
Meis homeobox 2
chr19_-_39108568 1.35 ENST00000586296.1
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr7_+_21467642 1.33 ENST00000222584.3
ENST00000432066.2
SP4
Sp4 transcription factor
chr17_-_47755436 1.29 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
SPOP
speckle-type POZ protein
chr9_+_100745615 1.29 ENST00000339399.4
ANP32B
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr1_+_212458834 1.28 ENST00000261461.2
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr3_+_193853927 1.27 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr11_-_19263145 1.27 ENST00000532666.1
ENST00000527884.1
E2F8
E2F transcription factor 8
chr5_+_133861339 1.26 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15
jade family PHD finger 2
chr17_+_37618257 1.26 ENST00000447079.4
CDK12
cyclin-dependent kinase 12
chr5_+_137688285 1.24 ENST00000314358.5
KDM3B
lysine (K)-specific demethylase 3B
chr8_-_57123815 1.23 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr2_-_61697862 1.22 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr13_-_52027134 1.21 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr19_+_35759824 1.20 ENST00000343550.5
USF2
upstream transcription factor 2, c-fos interacting
chr17_-_42297092 1.19 ENST00000393606.3
UBTF
upstream binding transcription factor, RNA polymerase I
chr20_+_31350184 1.08 ENST00000328111.2
ENST00000353855.2
ENST00000348286.2
DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr10_+_21823243 1.05 ENST00000307729.7
ENST00000377091.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr19_+_35759968 1.05 ENST00000222305.3
ENST00000595068.1
ENST00000379134.3
ENST00000594064.1
ENST00000598058.1
USF2
upstream transcription factor 2, c-fos interacting
chr12_+_52445191 1.05 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr19_-_39108552 1.04 ENST00000591517.1
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr2_-_148778258 1.04 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4
origin recognition complex, subunit 4
chr12_-_6716569 1.04 ENST00000544040.1
ENST00000545942.1
CHD4
chromodomain helicase DNA binding protein 4
chr16_+_15737124 1.03 ENST00000396355.1
ENST00000396353.2
NDE1
nudE neurodevelopment protein 1
chr10_+_35416223 1.03 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr15_-_37392703 1.02 ENST00000382766.2
ENST00000444725.1
MEIS2
Meis homeobox 2
chr17_+_7155343 1.00 ENST00000573513.1
ENST00000354429.2
ENST00000574255.1
ENST00000396627.2
ENST00000356683.2
ELP5
elongator acetyltransferase complex subunit 5
chr3_+_157823609 0.99 ENST00000480820.1
RSRC1
arginine/serine-rich coiled-coil 1
chr9_-_124991124 0.99 ENST00000394319.4
ENST00000340587.3
LHX6
LIM homeobox 6
chr12_-_6716534 0.98 ENST00000544484.1
ENST00000309577.6
ENST00000357008.2
CHD4
chromodomain helicase DNA binding protein 4
chr6_+_44238203 0.98 ENST00000451188.2
TMEM151B
transmembrane protein 151B
chr9_-_20622478 0.98 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr10_-_13390021 0.98 ENST00000537130.1
SEPHS1
selenophosphate synthetase 1
chr1_+_27022485 0.96 ENST00000324856.7
ARID1A
AT rich interactive domain 1A (SWI-like)
chr1_+_28995231 0.95 ENST00000373816.1
GMEB1
glucocorticoid modulatory element binding protein 1
chr17_-_46703826 0.95 ENST00000550387.1
ENST00000311177.5
HOXB9
homeobox B9
chr1_+_2985760 0.95 ENST00000378391.2
ENST00000514189.1
ENST00000270722.5
PRDM16
PR domain containing 16
chr12_-_51611477 0.95 ENST00000389243.4
POU6F1
POU class 6 homeobox 1
chr12_+_53774423 0.92 ENST00000426431.2
SP1
Sp1 transcription factor
chr19_-_39108643 0.90 ENST00000396857.2
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr19_-_39330818 0.89 ENST00000594769.1
ENST00000602021.1
AC104534.3
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
chr1_-_151431647 0.88 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ
pogo transposable element with ZNF domain
chr18_+_29672573 0.88 ENST00000578107.1
ENST00000257190.5
ENST00000580499.1
RNF138
ring finger protein 138, E3 ubiquitin protein ligase
chr15_-_56535464 0.87 ENST00000559447.2
ENST00000422057.1
ENST00000317318.6
ENST00000423270.1
RFX7
regulatory factor X, 7
chrX_-_129244454 0.87 ENST00000308167.5
ELF4
E74-like factor 4 (ets domain transcription factor)
chr8_-_103136481 0.87 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
NCALD
neurocalcin delta
chrX_-_129244655 0.86 ENST00000335997.7
ELF4
E74-like factor 4 (ets domain transcription factor)
chr7_-_148581251 0.86 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr17_-_7120525 0.86 ENST00000447163.1
ENST00000399506.2
ENST00000302955.6
DLG4
discs, large homolog 4 (Drosophila)
chr15_-_45480153 0.86 ENST00000560471.1
ENST00000560540.1
SHF
Src homology 2 domain containing F
chr6_-_29595779 0.85 ENST00000355973.3
ENST00000377012.4
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr15_-_37390482 0.85 ENST00000559085.1
ENST00000397624.3
MEIS2
Meis homeobox 2
chr17_-_77813186 0.85 ENST00000448310.1
ENST00000269397.4
CBX4
chromobox homolog 4
chr6_-_32160622 0.85 ENST00000487761.1
ENST00000375040.3
GPSM3
G-protein signaling modulator 3
chr7_+_153749732 0.83 ENST00000377770.3
DPP6
dipeptidyl-peptidase 6
chr15_-_37391507 0.82 ENST00000557796.2
ENST00000397620.2
MEIS2
Meis homeobox 2
chr15_-_69113218 0.82 ENST00000560303.1
ENST00000465139.2
ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr17_+_43299156 0.81 ENST00000331495.3
FMNL1
formin-like 1
chr11_+_85955787 0.79 ENST00000528180.1
EED
embryonic ectoderm development
chr19_-_12912657 0.79 ENST00000301522.2
PRDX2
peroxiredoxin 2
chr6_-_41909191 0.79 ENST00000512426.1
ENST00000372987.4
CCND3
cyclin D3
chr22_-_29138386 0.78 ENST00000544772.1
CHEK2
checkpoint kinase 2
chr5_-_137674000 0.78 ENST00000510119.1
ENST00000513970.1
CDC25C
cell division cycle 25C
chr19_-_12912601 0.78 ENST00000334482.5
PRDX2
peroxiredoxin 2
chr17_-_16875371 0.77 ENST00000437538.2
ENST00000583789.1
ENST00000261652.2
ENST00000579315.1
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr17_+_65821636 0.77 ENST00000544778.2
BPTF
bromodomain PHD finger transcription factor
chr1_+_155178481 0.76 ENST00000368376.3
MTX1
metaxin 1
chr2_-_176032843 0.76 ENST00000392544.1
ENST00000409499.1
ENST00000426833.3
ENST00000392543.2
ENST00000538946.1
ENST00000487334.2
ENST00000409833.1
ENST00000409635.1
ENST00000264110.2
ENST00000345739.5
ATF2
activating transcription factor 2
chr2_-_172017393 0.76 ENST00000442919.2
TLK1
tousled-like kinase 1
chr7_-_154794763 0.75 ENST00000404141.1
PAXIP1
PAX interacting (with transcription-activation domain) protein 1
chr18_-_5296001 0.75 ENST00000357006.4
ZBTB14
zinc finger and BTB domain containing 14
chr1_+_93544821 0.75 ENST00000370303.4
MTF2
metal response element binding transcription factor 2
chr7_-_154794621 0.74 ENST00000419436.1
ENST00000397192.1
PAXIP1
PAX interacting (with transcription-activation domain) protein 1
chr1_-_151431909 0.74 ENST00000361398.3
ENST00000271715.2
POGZ
pogo transposable element with ZNF domain
chr3_+_14989186 0.73 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr6_+_20403997 0.73 ENST00000535432.1
E2F3
E2F transcription factor 3
chr1_+_93544791 0.73 ENST00000545708.1
ENST00000540243.1
ENST00000370298.4
MTF2
metal response element binding transcription factor 2
chr7_-_148581360 0.72 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr4_-_151936416 0.71 ENST00000510413.1
ENST00000507224.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr18_+_55102917 0.71 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr10_-_12084770 0.71 ENST00000357604.5
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr2_-_174828892 0.71 ENST00000418194.2
SP3
Sp3 transcription factor
chrX_-_70474910 0.71 ENST00000373988.1
ENST00000373998.1
ZMYM3
zinc finger, MYM-type 3
chr11_-_46142615 0.70 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr21_-_40720974 0.69 ENST00000380748.1
HMGN1
high mobility group nucleosome binding domain 1
chr11_-_57103327 0.69 ENST00000529002.1
ENST00000278412.2
SSRP1
structure specific recognition protein 1
chr19_+_49622646 0.69 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr3_+_14989076 0.68 ENST00000413118.1
ENST00000425241.1
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr4_+_38665810 0.68 ENST00000261438.5
ENST00000514033.1
KLF3
Kruppel-like factor 3 (basic)
chr14_+_24540731 0.67 ENST00000558859.1
ENST00000559197.1
ENST00000560828.1
ENST00000216775.2
ENST00000560884.1
CPNE6
copine VI (neuronal)
chr16_-_31021717 0.67 ENST00000565419.1
STX1B
syntaxin 1B
chr2_-_214014959 0.67 ENST00000442445.1
ENST00000457361.1
ENST00000342002.2
IKZF2
IKAROS family zinc finger 2 (Helios)
chr8_-_124428569 0.66 ENST00000521903.1
ATAD2
ATPase family, AAA domain containing 2
chr4_-_105416039 0.66 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr1_+_27022839 0.66 ENST00000457599.2
ARID1A
AT rich interactive domain 1A (SWI-like)
chrX_-_118827333 0.66 ENST00000360156.7
ENST00000354228.4
ENST00000489216.1
ENST00000354416.3
ENST00000394610.1
ENST00000343984.5
SEPT6
septin 6
chr19_-_4066890 0.66 ENST00000322357.4
ZBTB7A
zinc finger and BTB domain containing 7A
chr15_-_70388943 0.66 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr15_-_70388599 0.65 ENST00000560996.1
ENST00000558201.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr14_-_21994525 0.65 ENST00000538754.1
SALL2
spalt-like transcription factor 2
chr15_-_37391614 0.65 ENST00000219869.9
MEIS2
Meis homeobox 2
chr1_-_53018654 0.64 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
ZCCHC11
zinc finger, CCHC domain containing 11
chr8_-_22550815 0.64 ENST00000317216.2
EGR3
early growth response 3
chr11_+_134201768 0.64 ENST00000535456.2
ENST00000339772.7
GLB1L2
galactosidase, beta 1-like 2
chr12_+_53817633 0.64 ENST00000257863.4
ENST00000550311.1
ENST00000379791.3
AMHR2
anti-Mullerian hormone receptor, type II
chr11_+_64009072 0.63 ENST00000535135.1
ENST00000394540.3
FKBP2
FK506 binding protein 2, 13kDa
chr12_+_7037461 0.63 ENST00000396684.2
ATN1
atrophin 1
chr15_-_65477637 0.62 ENST00000300107.3
CLPX
caseinolytic mitochondrial matrix peptidase chaperone subunit
chr1_+_2985726 0.62 ENST00000511072.1
ENST00000378398.3
ENST00000441472.2
ENST00000442529.2
PRDM16
PR domain containing 16
chr20_-_50808290 0.62 ENST00000346617.4
ENST00000371515.4
ENST00000371518.2
ZFP64
ZFP64 zinc finger protein
chr1_+_154975110 0.62 ENST00000535420.1
ENST00000368426.3
ZBTB7B
zinc finger and BTB domain containing 7B
chr17_-_7120498 0.62 ENST00000485100.1
DLG4
discs, large homolog 4 (Drosophila)
chr16_-_31021921 0.61 ENST00000215095.5
STX1B
syntaxin 1B
chr14_-_21493123 0.61 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG2
NDRG family member 2
chr1_+_182808474 0.61 ENST00000367549.3
DHX9
DEAH (Asp-Glu-Ala-His) box helicase 9
chr7_+_23146271 0.60 ENST00000545771.1
KLHL7
kelch-like family member 7
chr16_-_4323015 0.60 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr10_-_23003460 0.60 ENST00000376573.4
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr2_-_172017343 0.60 ENST00000431350.2
ENST00000360843.3
TLK1
tousled-like kinase 1
chr6_+_106534192 0.59 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr3_-_53080047 0.59 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1
Scm-like with four mbt domains 1
chr14_+_66975213 0.59 ENST00000543237.1
ENST00000305960.9
GPHN
gephyrin
chr5_+_36876833 0.58 ENST00000282516.8
ENST00000448238.2
NIPBL
Nipped-B homolog (Drosophila)
chrX_-_118739835 0.58 ENST00000542113.1
ENST00000304449.5
NKRF
NFKB repressing factor
chr18_+_657578 0.58 ENST00000323274.10
TYMS
thymidylate synthetase
chr1_+_155178518 0.58 ENST00000316721.4
MTX1
metaxin 1
chr7_+_20370746 0.58 ENST00000222573.4
ITGB8
integrin, beta 8
chr5_+_49963239 0.58 ENST00000505554.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr5_+_126112794 0.57 ENST00000261366.5
ENST00000395354.1
LMNB1
lamin B1
chr2_-_200323414 0.57 ENST00000443023.1
SATB2
SATB homeobox 2
chr19_-_17356697 0.57 ENST00000291442.3
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr17_-_41132010 0.57 ENST00000409103.1
ENST00000360221.4
PTGES3L-AARSD1
PTGES3L-AARSD1 readthrough
chr2_+_232572361 0.57 ENST00000409321.1
PTMA
prothymosin, alpha
chr1_-_167906277 0.57 ENST00000271373.4
MPC2
mitochondrial pyruvate carrier 2
chr3_+_184033135 0.57 ENST00000424196.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr16_-_70472946 0.57 ENST00000342907.2
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr15_+_74833518 0.56 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr2_+_61108771 0.56 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chrX_-_70474499 0.55 ENST00000353904.2
ZMYM3
zinc finger, MYM-type 3
chr12_+_57853918 0.55 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI1
GLI family zinc finger 1
chr18_+_32556892 0.55 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr1_+_155036204 0.54 ENST00000368409.3
ENST00000359751.4
ENST00000427683.2
ENST00000556931.1
ENST00000505139.1
EFNA4
EFNA3
EFNA3
ephrin-A4
ephrin-A3
Ephrin-A3; Uncharacterized protein; cDNA FLJ57652, highly similar to Ephrin-A3
chr8_+_21777159 0.54 ENST00000434536.1
ENST00000252512.9
XPO7
exportin 7
chr14_-_21566731 0.54 ENST00000360947.3
ZNF219
zinc finger protein 219
chr5_-_168006591 0.54 ENST00000239231.6
PANK3
pantothenate kinase 3
chr17_-_6459802 0.54 ENST00000262483.8
PITPNM3
PITPNM family member 3
chr5_-_134369973 0.53 ENST00000265340.7
PITX1
paired-like homeodomain 1
chr12_-_53601055 0.53 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
ITGB7
integrin, beta 7
chr1_+_16085244 0.53 ENST00000400773.1
FBLIM1
filamin binding LIM protein 1
chr6_+_34204642 0.53 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr14_+_29236269 0.53 ENST00000313071.4
FOXG1
forkhead box G1
chr9_-_124990680 0.53 ENST00000541397.2
ENST00000560485.1
LHX6
LIM homeobox 6
chrX_-_70473957 0.53 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
ZMYM3
zinc finger, MYM-type 3
chr3_+_189507432 0.53 ENST00000354600.5
TP63
tumor protein p63
chr6_+_12012536 0.52 ENST00000379388.2
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr1_+_116184566 0.52 ENST00000355485.2
ENST00000369510.4
VANGL1
VANGL planar cell polarity protein 1
chr5_+_49962772 0.52 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr7_-_150754935 0.52 ENST00000297518.4
CDK5
cyclin-dependent kinase 5
chr3_-_157823839 0.52 ENST00000425436.3
ENST00000389589.4
ENST00000441443.2
SHOX2
short stature homeobox 2
chr14_-_21493884 0.52 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG2
NDRG family member 2

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 15.3 GO:0000812 Swr1 complex(GO:0000812)
0.5 6.9 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3 1.5 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.3 0.9 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 1.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 0.7 GO:0031213 RSF complex(GO:0031213)
0.2 1.2 GO:0016589 NURF complex(GO:0016589)
0.2 0.6 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.2 2.6 GO:0045120 pronucleus(GO:0045120)
0.2 1.5 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.8 GO:0008537 proteasome activator complex(GO:0008537)
0.1 1.7 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.7 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 1.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.2 GO:0032039 integrator complex(GO:0032039)
0.1 0.5 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 1.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.6 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.1 0.6 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 2.9 GO:0071564 npBAF complex(GO:0071564)
0.1 3.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 6.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.3 GO:0043291 RAVE complex(GO:0043291)
0.1 5.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.3 GO:0035838 growing cell tip(GO:0035838)
0.1 0.7 GO:0097227 septin complex(GO:0031105) sperm annulus(GO:0097227)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.5 GO:0072487 MSL complex(GO:0072487)
0.1 1.9 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.3 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.3 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 1.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 0.9 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 3.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.8 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.0 GO:0032059 bleb(GO:0032059)
0.1 8.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.4 GO:0000125 PCAF complex(GO:0000125)
0.1 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 1.0 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 2.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 5.2 GO:0055037 recycling endosome(GO:0055037)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.0 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.3 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 5.1 GO:0000785 chromatin(GO:0000785)
0.0 0.1 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0097346 INO80-type complex(GO:0097346)
0.0 0.5 GO:0097546 ciliary base(GO:0097546)
0.0 1.4 GO:0016605 PML body(GO:0016605)
0.0 0.0 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.0 GO:0044305 calyx of Held(GO:0044305)
0.0 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.5 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.6 10.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.5 1.5 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.4 1.3 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.4 6.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.4 3.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.4 4.0 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.3 0.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 1.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.3 13.9 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.3 1.0 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.2 1.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 2.6 GO:0051430 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 2.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 0.7 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 1.6 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 1.8 GO:0043426 MRF binding(GO:0043426)
0.2 1.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 1.4 GO:0008142 oxysterol binding(GO:0008142)
0.2 2.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 0.6 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 2.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.9 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.6 GO:0008940 nitrate reductase activity(GO:0008940)
0.1 0.6 GO:0036033 mediator complex binding(GO:0036033)
0.1 7.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.4 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.4 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 7.0 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.0 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.5 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.5 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 1.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.7 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.6 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.5 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 0.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.9 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.5 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.8 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 4.2 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.6 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 4.1 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 1.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.8 GO:0005030 GPI-linked ephrin receptor activity(GO:0005004) neurotrophin receptor activity(GO:0005030)
0.1 0.3 GO:0004104 acetylcholinesterase activity(GO:0003990) cholinesterase activity(GO:0004104)
0.1 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.4 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.1 0.6 GO:0045545 syndecan binding(GO:0045545)
0.1 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.2 GO:0004324 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 0.4 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 1.0 GO:0005522 profilin binding(GO:0005522)
0.1 0.7 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.1 1.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 1.0 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 2.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 1.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 1.3 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.3 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.6 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.4 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 3.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.7 GO:0000049 tRNA binding(GO:0000049)
0.0 0.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 1.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0043274 phospholipase binding(GO:0043274)
0.0 1.9 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.2 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 1.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 2.7 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 2.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 1.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 1.0 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.0 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.6 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 1.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.6 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 8.2 GO:0043565 sequence-specific DNA binding(GO:0043565)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 2.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 0.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 5.1 PID TNF PATHWAY TNF receptor signaling pathway
0.1 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 1.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 5.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 2.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 0.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 3.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 3.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.9 PID ATM PATHWAY ATM pathway
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 PID FOXO PATHWAY FoxO family signaling
0.0 0.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.6 PID SHP2 PATHWAY SHP2 signaling
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.2 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
1.0 7.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.9 4.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.6 2.4 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.6 1.8 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.5 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.5 1.6 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.5 1.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.5 1.5 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.4 1.3 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.4 1.3 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.4 2.5 GO:0072553 terminal button organization(GO:0072553)
0.4 1.3 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.4 2.6 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.3 17.8 GO:0043486 histone exchange(GO:0043486)
0.3 1.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.3 1.6 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.3 1.3 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.3 2.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.3 2.8 GO:0060717 chorion development(GO:0060717)
0.3 2.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.3 0.6 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.3 1.5 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.3 0.8 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.3 1.6 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.3 0.8 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.3 1.0 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.3 1.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.3 1.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.3 1.0 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.2 1.2 GO:0021759 globus pallidus development(GO:0021759)
0.2 0.7 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2 0.9 GO:0002840 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.2 1.4 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.2 2.4 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.2 0.6 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.2 1.6 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.2 0.6 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.2 0.6 GO:0061010 gall bladder development(GO:0061010)
0.2 0.8 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.2 1.5 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 0.4 GO:0043634 polyadenylation-dependent RNA catabolic process(GO:0043633) polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.2 1.8 GO:0051382 kinetochore assembly(GO:0051382)
0.2 0.5 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.2 0.7 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.2 1.7 GO:0001866 NK T cell proliferation(GO:0001866)
0.2 1.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 2.5 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.2 0.5 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.2 0.6 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2 0.5 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 1.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.6 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.6 GO:0019860 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) transformation of host cell by virus(GO:0019087) uracil metabolic process(GO:0019860)
0.1 1.4 GO:0007379 segment specification(GO:0007379)
0.1 1.2 GO:0072718 response to cisplatin(GO:0072718)
0.1 0.4 GO:0097254 renal tubular secretion(GO:0097254)
0.1 7.1 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.5 GO:0007418 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.1 0.4 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.5 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 2.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.8 GO:0051013 microtubule severing(GO:0051013)
0.1 0.3 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.8 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 1.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.9 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 1.8 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 1.1 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.1 0.6 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.1 0.6 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.7 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 1.1 GO:0061469 response to corticotropin-releasing hormone(GO:0043435) regulation of type B pancreatic cell proliferation(GO:0061469) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.5 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 0.3 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 0.7 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.5 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.5 GO:0060406 positive regulation of penile erection(GO:0060406)
0.1 0.5 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.1 0.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 1.0 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.1 GO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.1 2.3 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 0.7 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.3 GO:2000824 determination of left/right asymmetry in lateral mesoderm(GO:0003140) nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry(GO:1900094) nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900164) negative regulation of androgen receptor activity(GO:2000824)
0.1 0.3 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.1 0.3 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.5 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.8 GO:0032909 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.1 0.3 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 1.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.1 2.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.9 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.9 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 0.5 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.2 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 2.2 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 5.0 GO:0008542 visual learning(GO:0008542)
0.1 0.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.7 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.1 0.4 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.2 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.1 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.3 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.3 GO:1904327 maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.1 1.0 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 1.2 GO:0016180 snRNA processing(GO:0016180)
0.1 0.2 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 1.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.3 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.0 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.2 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 0.8 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.6 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.2 GO:0097501 stress response to metal ion(GO:0097501)
0.1 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.1 1.0 GO:0051014 actin filament severing(GO:0051014)
0.1 1.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 4.6 GO:0016575 histone deacetylation(GO:0016575)
0.1 0.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.4 GO:2000370 positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0 0.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 1.6 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.8 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.2 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.5 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.8 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 2.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 1.0 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.5 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.4 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.5 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.7 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.0 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 1.0 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.6 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.1 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.4 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.6 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.3 GO:0044344 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.0 GO:0003160 endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
0.0 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.7 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.4 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.6 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.9 GO:0003170 heart valve development(GO:0003170)
0.0 0.1 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.7 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.3 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.3 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.1 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.1 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.3 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0051384 response to glucocorticoid(GO:0051384)
0.0 0.3 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.2 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.8 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 0.3 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 1.2 GO:0000375 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 1.2 GO:0001892 embryonic placenta development(GO:0001892)
0.0 0.3 GO:0007625 grooming behavior(GO:0007625)
0.0 0.4 GO:0090398 cellular senescence(GO:0090398)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.7 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.6 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 1.0 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.4 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.0 GO:0061743 motor learning(GO:0061743)
0.0 1.2 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.2 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.4 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.4 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0051403 stress-activated MAPK cascade(GO:0051403)
0.0 0.3 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.4 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.4 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.1 GO:1900125 regulation of hyaluronan biosynthetic process(GO:1900125)
0.0 0.3 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.5 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.3 GO:2000352 negative regulation of endothelial cell apoptotic process(GO:2000352)
0.0 0.2 GO:0001964 startle response(GO:0001964)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.0 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.3 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 1.0 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.0 GO:0036269 swimming behavior(GO:0036269)
0.0 0.5 GO:0051028 mRNA transport(GO:0051028)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.3 7.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 2.7 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 2.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 3.4 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 0.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 2.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 3.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.5 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 0.8 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.1 3.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 2.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.9 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 1.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 2.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 1.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.7 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.0 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.8 REACTOME CHROMOSOME MAINTENANCE Genes involved in Chromosome Maintenance
0.0 0.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events