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ENCODE cell lines, expression (Ernst 2011)

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Results for ZNF8

Z-value: 0.33

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Transcription factors associated with ZNF8

Gene Symbol Gene ID Gene Info
ZNF8
ENSG00000083842.8 ZNF8
ZNF8
ENSG00000273439.1 ZNF8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF8hg19_v2_chr19_+_58790314_587903580.097.4e-01Click!

Activity profile of ZNF8 motif

Sorted Z-values of ZNF8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF8

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_106959718 0.60 ENST00000369066.3
 AIM1
 absent in melanoma 1
chrX_+_128913906 0.49 ENST00000356892.3
 SASH3
 SAM and SH3 domain containing 3
chr6_+_29691198 0.45 ENST00000440587.2
ENST00000434407.2
 HLA-F
 major histocompatibility complex, class I, F
chr6_+_29691056 0.44 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
 HLA-F
 major histocompatibility complex, class I, F
chr12_-_46662772 0.35 ENST00000549049.1
ENST00000439706.1
ENST00000398637.5
 SLC38A1
 solute carrier family 38, member 1
chr2_-_172290482 0.34 ENST00000442541.1
ENST00000392599.2
ENST00000375258.4
 METTL8
 methyltransferase like 8
chr19_+_35739782 0.27 ENST00000347609.4
 LSR
 lipolysis stimulated lipoprotein receptor
chr19_+_35739897 0.27 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
 LSR
 lipolysis stimulated lipoprotein receptor
chr17_+_75181292 0.25 ENST00000431431.2
 SEC14L1
 SEC14-like 1 (S. cerevisiae)
chr6_+_53659746 0.24 ENST00000370888.1
 LRRC1
 leucine rich repeat containing 1
chr22_+_37415676 0.22 ENST00000401419.3
 MPST
 mercaptopyruvate sulfurtransferase
chr11_-_58345569 0.22 ENST00000528954.1
ENST00000528489.1
 LPXN
 leupaxin
chr1_+_214161272 0.21 ENST00000498508.2
ENST00000366958.4
 PROX1
 prospero homeobox 1
chr22_+_37415728 0.20 ENST00000404802.3
 MPST
 mercaptopyruvate sulfurtransferase
chr22_+_37415700 0.19 ENST00000397129.1
 MPST
 mercaptopyruvate sulfurtransferase
chr15_+_85523671 0.18 ENST00000310298.4
ENST00000557957.1
 PDE8A
 phosphodiesterase 8A
chr22_+_37415776 0.18 ENST00000341116.3
ENST00000429360.2
ENST00000404393.1
 MPST
 mercaptopyruvate sulfurtransferase
chr3_-_9994021 0.16 ENST00000411976.2
ENST00000412055.1
 PRRT3
 proline-rich transmembrane protein 3
chr6_-_26056695 0.15 ENST00000343677.2
 HIST1H1C
 histone cluster 1, H1c
chr7_+_117824086 0.15 ENST00000249299.2
ENST00000424702.1
 NAA38
 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr5_-_137911049 0.13 ENST00000297185.3
 HSPA9
 heat shock 70kDa protein 9 (mortalin)
chr13_+_53226963 0.12 ENST00000343788.6
ENST00000535397.1
ENST00000310528.8
 SUGT1
 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
chr10_+_135192695 0.11 ENST00000368539.4
ENST00000278060.5
ENST00000357296.3
 PAOX
 polyamine oxidase (exo-N4-amino)
chr2_+_169926047 0.10 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
 DHRS9
 dehydrogenase/reductase (SDR family) member 9
chr1_-_235292250 0.10 ENST00000366607.4
 TOMM20
 translocase of outer mitochondrial membrane 20 homolog (yeast)
chr11_-_46638720 0.10 ENST00000326737.3
 HARBI1
 harbinger transposase derived 1
chr7_+_100303676 0.10 ENST00000303151.4
 POP7
 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
chr17_+_48624450 0.10 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
 SPATA20
 spermatogenesis associated 20
chr9_-_32552551 0.08 ENST00000360538.2
ENST00000379858.1
 TOPORS
 topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
chr13_+_21750780 0.08 ENST00000309594.4
 MRP63
 mitochondrial ribosomal protein 63
chr10_-_1034237 0.08 ENST00000381466.1
 AL359878.1
 Uncharacterized protein
chrX_+_129535937 0.07 ENST00000305536.6
ENST00000370947.1
 RBMX2
 RNA binding motif protein, X-linked 2
chr19_+_37998031 0.07 ENST00000586138.1
ENST00000588578.1
ENST00000587986.1
 ZNF793
 zinc finger protein 793
chr2_+_172290707 0.06 ENST00000375255.3
ENST00000539783.1
 DCAF17
 DDB1 and CUL4 associated factor 17
chr8_-_109260897 0.06 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
 EIF3E
 eukaryotic translation initiation factor 3, subunit E
chr2_+_87144738 0.06 ENST00000559485.1
 RGPD1
 RANBP2-like and GRIP domain containing 1
chr2_+_198365122 0.05 ENST00000604458.1
 HSPE1-MOB4
 HSPE1-MOB4 readthrough
chr16_+_21964662 0.04 ENST00000561553.1
ENST00000565331.1
 UQCRC2
 ubiquinol-cytochrome c reductase core protein II
chr22_+_30163340 0.04 ENST00000330029.6
ENST00000401406.3
 UQCR10
 ubiquinol-cytochrome c reductase, complex III subunit X
chr11_+_46638805 0.04 ENST00000434074.1
ENST00000312040.4
ENST00000451945.1
 ATG13
 autophagy related 13
chr4_-_77069573 0.04 ENST00000264883.3
 NUP54
 nucleoporin 54kDa
chr19_-_18392422 0.03 ENST00000252818.3
 JUND
 jun D proto-oncogene
chr1_-_100715372 0.03 ENST00000370131.3
ENST00000370132.4
 DBT
 dihydrolipoamide branched chain transacylase E2
chr2_-_240322643 0.02 ENST00000345617.3
 HDAC4
 histone deacetylase 4
chr20_+_37377085 0.02 ENST00000243903.4
 ACTR5
 ARP5 actin-related protein 5 homolog (yeast)
chr19_-_5903714 0.02 ENST00000586349.1
ENST00000585661.1
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000252675.5
 AC024592.12
NDUFA11
FUT5
 Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr8_+_145064233 0.01 ENST00000529301.1
ENST00000395068.4
 GRINA
 glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr14_+_51706886 0.01 ENST00000457354.2
 TMX1
 thioredoxin-related transmembrane protein 1
chr5_+_10353780 0.01 ENST00000449913.2
ENST00000503788.1
ENST00000274140.5
 MARCH6
 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
chr7_-_99698338 0.01 ENST00000354230.3
ENST00000425308.1
 MCM7
 minichromosome maintenance complex component 7
chr1_-_70671216 0.00 ENST00000370952.3
 LRRC40
 leucine rich repeat containing 40
chr1_+_70671363 0.00 ENST00000370951.1
ENST00000370950.3
ENST00000405432.1
ENST00000454435.2
 SRSF11
 serine/arginine-rich splicing factor 11

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.1 0.9 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.3 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.4 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0009440 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.1 0.5 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.9 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.2 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.1 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.5 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.0 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)