Motif ID: STAT1,3.p3

Z-value: 1.187


Transcription factors associated with STAT1,3.p3:

Gene SymbolEntrez IDGene Name
STAT1 6772 signal transducer and activator of transcription 1, 91kDa
STAT3 6774 signal transducer and activator of transcription 3 (acute-phase response factor)



Activity profile for motif STAT1,3.p3.

activity profile for motif STAT1,3.p3


Sorted Z-values histogram for motif STAT1,3.p3

Sorted Z-values for motif STAT1,3.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT1,3.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_157313179 3.302 NM_004833
AIM2
absent in melanoma 2
chr1_-_143706196 2.881 PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_143706265 2.804 PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_143706300 2.655 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chrX_-_154216929 1.587 NM_001289
CLIC2
chloride intracellular channel 2
chr19_+_10242763 1.505 ICAM1
intercellular adhesion molecule 1
chr5_-_138753443 1.273 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr17_-_24491521 1.184 MYO18A
myosin XVIIIA
chr19_-_45022993 1.109 FBL
fibrillarin
chr12_-_8271460 1.059 NM_018088
FAM90A1
family with sequence similarity 90, member A1
chr1_-_158883666 1.013 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr9_-_85761451 0.910 C9orf64
chromosome 9 open reading frame 64
chr9_-_85761472 0.909 NM_032307
C9orf64
chromosome 9 open reading frame 64
chr19_-_11550576 0.901 NM_001111034
ACP5
acid phosphatase 5, tartrate resistant
chr22_-_49041786 0.866 MAPK12
mitogen-activated protein kinase 12
chr22_-_29833484 0.852 NM_080430
SELM
selenoprotein M
chr16_-_66075216 0.786 NM_001138
AGRP
agouti related protein homolog (mouse)
chr15_+_89300973 0.779 RCCD1
RCC1 domain containing 1
chr19_-_4853878 0.775 NM_001080523
ARRDC5
arrestin domain containing 5
chr9_-_85761353 0.745 C9orf64
chromosome 9 open reading frame 64
chr22_+_19191875 0.717 MED15
mediator complex subunit 15
chr15_+_89300995 0.713 RCCD1
RCC1 domain containing 1
chr4_-_129429433 0.709 NM_006320
PGRMC2
progesterone receptor membrane component 2
chr19_-_61596681 0.690 NM_144690
ZNF582
zinc finger protein 582
chr22_+_19191886 0.672 MED15
mediator complex subunit 15
chr22_+_19191898 0.669 MED15
mediator complex subunit 15
chr1_-_11841476 0.662 NM_002521
NPPB
natriuretic peptide B
chr22_+_19191884 0.657 NM_001003891
NM_015889
MED15

mediator complex subunit 15

chr22_+_19191859 0.647 MED15
mediator complex subunit 15
chr20_-_44370537 0.641 CDH22
cadherin 22, type 2
chr17_-_73867748 0.570 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr22_-_48437081 0.570 C22orf34
chromosome 22 open reading frame 34
chr12_-_119172339 0.542 NM_025157
PXN
paxillin
chr11_-_64247230 0.525 NM_015080
NM_138732
NRXN2

neurexin 2

chr16_-_3049336 0.479


chr15_-_41409979 0.468 NM_014793
LCMT2
leucine carboxyl methyltransferase 2
chr19_+_10242516 0.468 NM_000201
ICAM1
intercellular adhesion molecule 1
chr8_-_102872354 0.467 NCALD
neurocalcin delta
chr19_-_53941835 0.465 NM_182575
IZUMO1
izumo sperm-egg fusion 1
chr2_+_170074457 0.461 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr15_+_88609837 0.457 NM_001033088
NGRN
neugrin, neurite outgrowth associated
chr4_-_145281237 0.446 NM_002099
GYPA
glycophorin A (MNS blood group)
chr8_-_102872372 0.437 NCALD
neurocalcin delta
chr8_-_42742729 0.429 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr15_+_41410163 0.419 NM_001012969
NM_001159280
ADAL

adenosine deaminase-like

chr11_-_605920 0.390 IRF7
interferon regulatory factor 7
chr11_+_47958835 0.387 PTPRJ
protein tyrosine phosphatase, receptor type, J
chr2_+_102401580 0.381 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr1_+_240078655 0.378 NM_003686
NM_006027
EXO1

exonuclease 1

chr8_+_27238979 0.376 NM_173175
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr22_+_23333610 0.373 NM_001032365
GGT1
gamma-glutamyltransferase 1
chr11_+_61861349 0.372 NM_001083926
NM_025080
ASRGL1

asparaginase like 1

chrX_-_100434700 0.369 NM_024885
TAF7L
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr10_-_61139328 0.365 NM_194298
LOC100129721
SLC16A9
hypothetical protein LOC100129721
solute carrier family 16, member 9 (monocarboxylic acid transporter 9)
chr6_-_31007905 0.364 NM_205854
SFTA2
surfactant associated 2
chr5_-_180220881 0.360 NM_001172638
NM_152283
ZFP62

zinc finger protein 62 homolog (mouse)

chr19_-_53841064 0.351 NM_001217
CA11
carbonic anhydrase XI
chr6_-_27548438 0.349 NM_007149
ZNF184
zinc finger protein 184
chr19_-_63775901 0.347 MZF1
myeloid zinc finger 1
chr10_-_62882930 0.343 TMEM26
transmembrane protein 26
chr5_+_139924224 0.341 SLC35A4
solute carrier family 35, member A4
chr17_-_39333490 0.335 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr11_+_61861458 0.331 ASRGL1
asparaginase like 1
chrX_+_134803450 0.313 NM_018666
SAGE1
sarcoma antigen 1
chr12_-_116021473 0.310 NM_001168325
NM_017899
TESC

tescalcin

chr20_+_54420574 0.306 NM_001164116
NM_001164114
NM_001164115
NM_020356
CASS4



Cas scaffolding protein family member 4



chr6_-_28412130 0.304 NM_030899
ZNF323
zinc finger protein 323
chr11_+_71387572 0.299 NM_001039659
NM_001039660
NM_173042
IL18BP


interleukin 18 binding protein


chr11_-_605998 0.295 NM_001572
NM_004029
IRF7

interferon regulatory factor 7

chr13_-_94751573 0.284 NM_001105515
NM_005845
ABCC4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

chr2_-_85948287 0.283 NM_001042437
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr5_-_133734616 0.281 CDKL3
cyclin-dependent kinase-like 3
chr20_+_2743613 0.279 NM_080739
C20orf141
chromosome 20 open reading frame 141
chr9_-_130078017 0.279 NM_004486
GOLGA2
golgin A2
chr14_+_73027361 0.273 NM_024644
C14orf169
chromosome 14 open reading frame 169
chr11_-_605649 0.269 NM_004031
IRF7
interferon regulatory factor 7
chr14_+_73027423 0.267 C14orf169
chromosome 14 open reading frame 169
chr14_+_73027410 0.265 C14orf169
chromosome 14 open reading frame 169
chr1_-_52272020 0.257 NM_138417
KTI12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr2_-_70042900 0.251 NM_152792
ASPRV1
aspartic peptidase, retroviral-like 1
chr16_-_3707450 0.250 NM_016292
TRAP1
TNF receptor-associated protein 1
chr19_+_49198916 0.248 NM_006300
ZNF230
zinc finger protein 230
chr17_-_73694669 0.248 NM_003258
TK1
thymidine kinase 1, soluble
chr8_+_96106362 0.247 NM_152416
C8orf38
chromosome 8 open reading frame 38
chr12_-_107238568 0.244 NM_001142345
CMKLR1
chemokine-like receptor 1
chr6_+_31648071 0.241 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr19_+_3713671 0.240 MRPL54
mitochondrial ribosomal protein L54
chr3_-_147696411 0.236 NM_020359
PLSCR2
phospholipid scramblase 2
chr5_+_133734768 0.226 NM_003337
UBE2B
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr19_-_43412152 0.219 NM_001135156
DPF1
D4, zinc and double PHD fingers family 1
chr3_+_46258875 0.218 NM_001164680
NM_001837
NM_178328
NM_178329
CCR3



chemokine (C-C motif) receptor 3



chr12_-_47735373 0.214 NM_003482
MLL2
myeloid/lymphoid or mixed-lineage leukemia 2
chr12_-_122322117 0.212 NM_004642
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr22_+_19191964 0.212 MED15
mediator complex subunit 15
chr8_+_11388918 0.209 NM_001715
BLK
B lymphoid tyrosine kinase
chr1_-_71285847 0.207 NM_001126044
NM_198714
NM_198715
NM_198716
NM_198717
NM_198718
NM_198719
PTGER3






prostaglandin E receptor 3 (subtype EP3)






chr19_+_45194782 0.199 NM_178544
ZNF546
zinc finger protein 546
chr9_+_131937163 0.199 GPR107
G protein-coupled receptor 107
chr4_-_176970895 0.198 GPM6A
glycoprotein M6A
chr3_-_121065112 0.196


chr15_-_73719546 0.192 NM_018285
IMP3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr19_+_53559468 0.191 NM_012451
SYNGR4
synaptogyrin 4
chr1_-_6376360 0.189 NM_007274
ACOT7
acyl-CoA thioesterase 7
chr1_-_151788341 0.189 NM_002960
S100A3
S100 calcium binding protein A3
chr19_-_4782711 0.184 NM_182919
TICAM1
toll-like receptor adaptor molecule 1
chr1_+_22842704 0.184 NM_001114101
NM_172369
C1QC

complement component 1, q subcomponent, C chain

chrX_-_30505804 0.183 NM_025159
CXorf21
chromosome X open reading frame 21
chr19_-_844215 0.182 NM_005481
MED16
mediator complex subunit 16
chr9_+_135994734 0.181 NM_052821
WDR5
WD repeat domain 5
chr5_-_39110251 0.180 NM_152756
RICTOR
RPTOR independent companion of MTOR, complex 2
chr7_-_148788799 0.179 NM_015694
ZNF777
zinc finger protein 777
chr17_-_39822366 0.177 NM_000419
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr2_+_30523586 0.174 NM_182551
NM_001002257
LCLAT1

lysocardiolipin acyltransferase 1

chr1_+_34405070 0.172 NM_032884
C1orf94
chromosome 1 open reading frame 94
chr1_+_54291847 0.171 NM_153035
TCEANC2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr9_-_35608300 0.169 NM_001782
CD72
CD72 molecule
chr17_-_8020332 0.168 NM_032354
NM_183065
TMEM107

transmembrane protein 107

chr14_+_23905984 0.167 NM_001136022
NM_001198967
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr6_+_41411505 0.167 NM_004828
NCR2
natural cytotoxicity triggering receptor 2
chr14_+_73027438 0.165 C14orf169
chromosome 14 open reading frame 169
chrX_-_134013644 0.164 NM_001078172
NM_001134321
FAM127B

family with sequence similarity 127, member B

chr1_-_210070736 0.163 NM_014873
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr5_-_177592406 0.160 NM_153373
AGXT2L2
alanine-glyoxylate aminotransferase 2-like 2
chr16_-_24876357 0.160 ARHGAP17
Rho GTPase activating protein 17
chr5_+_134237325 0.160 NM_024715
TXNDC15
thioredoxin domain containing 15
chr22_-_36212160 0.159 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr3_-_171070314 0.157 NM_024727
LRRC31
leucine rich repeat containing 31
chr20_-_33706532 0.157 RBM12
RNA binding motif protein 12
chr1_+_10457579 0.157 NM_004565
PEX14
peroxisomal biogenesis factor 14
chr1_-_154226484 0.156 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr22_-_18222337 0.149 C22orf29
chromosome 22 open reading frame 29
chr22_-_22426551 0.148 NM_013378
VPREB3
pre-B lymphocyte 3
chr5_+_178300799 0.146 NM_001178089
NM_001178090
NM_182594
ZNF454


zinc finger protein 454


chr9_-_133574928 0.145 NM_198679
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr19_+_18391211 0.145 NM_001009998
NM_032627
SSBP4

single stranded DNA binding protein 4

chr1_+_12002098 0.142 NM_021933
MIIP
migration and invasion inhibitory protein
chr1_+_12002138 0.141 MIIP
migration and invasion inhibitory protein
chr19_+_44959073 0.141 NM_001143832
LEUTX
leucine twenty homeobox
chr6_-_25834733 0.140 NM_170745
HIST1H2AA
histone cluster 1, H2aa
chr6_-_28411889 0.137 NM_001135216
ZNF323
zinc finger protein 323
chr14_+_77939845 0.135 NM_004796
NRXN3
neurexin 3
chrX_-_138742050 0.133 NM_001010986
NM_173694
ATP11C

ATPase, class VI, type 11C

chr1_+_45926433 0.132 NM_016486
TMEM69
transmembrane protein 69
chr3_-_15875932 0.132 NM_015199
ANKRD28
ankyrin repeat domain 28
chr5_-_177592157 0.132 AGXT2L2
alanine-glyoxylate aminotransferase 2-like 2
chr1_-_205186330 0.131 NM_002644
PIGR
polymeric immunoglobulin receptor
chr12_+_120548831 0.129 NM_032790
ORAI1
ORAI calcium release-activated calcium modulator 1
chr5_-_39110235 0.128 RICTOR
RPTOR independent companion of MTOR, complex 2
chr3_-_50335113 0.128 NM_003773
NM_033158
HYAL2

hyaluronoglucosaminidase 2

chr11_+_61204392 0.128 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr19_+_54669629 0.127 FLT3LG
fms-related tyrosine kinase 3 ligand
chr11_-_62218759 0.126 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr6_+_108722752 0.125 NM_145315
LACE1
lactation elevated 1
chr7_-_149631001 0.125 NM_001164459
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr20_+_34019942 0.124 NM_080834
C20orf152
chromosome 20 open reading frame 152
chr19_+_3713650 0.122 NM_172251
MRPL54
mitochondrial ribosomal protein L54
chr1_+_240078094 0.120 NM_130398
EXO1
exonuclease 1
chrX_+_154097894 0.113 NM_003372
VBP1
von Hippel-Lindau binding protein 1
chr19_+_17277476 0.113 NM_023937
MRPL34
mitochondrial ribosomal protein L34
chr20_+_33667160 0.112 NM_003116
SPAG4
sperm associated antigen 4
chr22_-_18222328 0.112 GNB1L
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr12_-_52179462 0.110 NM_001193511
NM_006301
MAP3K12

mitogen-activated protein kinase kinase kinase 12

chr16_+_68765428 0.110 NM_173619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr5_-_177592326 0.108 AGXT2L2
alanine-glyoxylate aminotransferase 2-like 2
chr9_-_74757735 0.108 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr6_-_32259974 0.107 NM_001136
NM_172197
AGER

advanced glycosylation end product-specific receptor

chr12_+_92488932 0.104 SOCS2
suppressor of cytokine signaling 2
chr19_-_49696322 0.103 NM_013256
ZNF180
zinc finger protein 180
chr8_+_103889733 0.103 FLJ45248
FLJ45248 protein
chr2_+_167468220 0.103 NM_001079810
NM_152381
XIRP2

xin actin-binding repeat containing 2

chr17_+_75851984 0.101


chr2_-_200424140 0.101 LOC348751
hypothetical LOC348751
chr19_-_844184 0.099 MED16
mediator complex subunit 16
chr15_+_56217686 0.098 NM_020980
AQP9
aquaporin 9
chr12_+_66328760 0.097 NM_003583
NM_006482
DYRK2

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2

chr19_-_3935152 0.096 EEF2
eukaryotic translation elongation factor 2
chr19_-_60664860 0.096 NM_001136201
NM_001136202
NM_024710
ISOC2


isochorismatase domain containing 2


chr10_-_38186984 0.096 ZNF248
zinc finger protein 248
chr1_-_201194062 0.093 ADIPOR1
adiponectin receptor 1
chr5_+_109052984 0.093


chr1_+_111571803 0.092 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr1_+_205328834 0.091 NM_001017365
NM_001017366
C4BPB

complement component 4 binding protein, beta

chr3_+_23962518 0.087 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr14_-_67211081 0.087 NM_006370
VTI1B
vesicle transport through interaction with t-SNAREs homolog 1B (yeast)
chr12_-_52356375 0.086 NM_005176
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr15_-_62173041 0.083 NM_001014812
NM_032231
FAM96A

family with sequence similarity 96, member A

chr5_-_139924013 0.081 APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr1_+_58899 0.080 NM_001005484
OR4F4
OR4F5
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 5
chr12_-_52975777 0.080 NM_006163
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr17_+_73694992 0.079 NM_001010982
NM_001145526
AFMID

arylformamidase

chr3_-_172109119 0.078 NM_020390
EIF5A2
eukaryotic translation initiation factor 5A2
chr1_+_194887630 0.078 NM_000186
NM_001014975
CFH

complement factor H

chr5_+_109052945 0.078 MAN2A1
mannosidase, alpha, class 2A, member 1
chr11_-_118471385 0.078 NM_002105
H2AFX
H2A histone family, member X
chr9_+_130078321 0.075 C9orf119
chromosome 9 open reading frame 119
chr14_-_20128721 0.075 NM_001024822
RNASE12
ribonuclease, RNase A family, 12 (non-active)
chr3_-_172109075 0.073 EIF5A2
eukaryotic translation initiation factor 5A2
chr12_-_92488767 0.072


chr15_-_41589958 0.072 NM_005657
TP53BP1
tumor protein p53 binding protein 1
chr3_+_37259684 0.072 NM_001172713
NM_002078
GOLGA4

golgin A4


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.