Motif ID: CREB1.p2

Z-value: 2.509


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_2081030010.263.3e-01Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_32755778 6.921 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr2_-_128285136 4.068 WDR33
WD repeat domain 33
chr2_-_128285214 3.726 NM_001006622
NM_001006623
NM_018383
WDR33


WD repeat domain 33


chr13_+_48720047 3.672 NM_001193478
NM_030911
CDADC1

cytidine and dCMP deaminase domain containing 1

chr1_+_119484529 3.642


chr7_-_19715127 3.218 NM_001002926
TWISTNB
TWIST neighbor
chr1_+_169721260 3.124 NM_015172
PRRC2C
proline-rich coiled-coil 2C
chr2_-_43676603 3.035 NM_001083953
NM_022065
THADA

thyroid adenoma associated

chr5_-_172130766 2.916 NM_004417
DUSP1
dual specificity phosphatase 1
chr2_+_192251105 2.753 NM_001031716
OBFC2A
oligonucleotide/oligosaccharide-binding fold containing 2A
chr16_+_18986459 2.504 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr6_+_126319540 2.473 NM_138571
HINT3
histidine triad nucleotide binding protein 3
chr5_-_133332173 2.472 NM_020199
C5orf15
chromosome 5 open reading frame 15
chr2_-_179051471 2.434 NM_001135212
NM_181342
FKBP7

FK506 binding protein 7

chr14_+_34521945 2.419 SRP54
signal recognition particle 54kDa
chr2_+_95432150 2.299 NM_016044
FAHD2A
fumarylacetoacetate hydrolase domain containing 2A
chr2_+_219453487 2.289 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr17_-_35337288 2.286 NM_139280
ORMDL3
ORM1-like 3 (S. cerevisiae)
chr16_-_3707450 2.215 NM_016292
TRAP1
TNF receptor-associated protein 1
chr20_+_36810510 2.214 NM_024855
ACTR5
ARP5 actin-related protein 5 homolog (yeast)
chr20_-_5048443 2.199 NM_182649
PCNA
proliferating cell nuclear antigen
chr5_+_148186348 2.192 NM_000024
ADRB2
adrenergic, beta-2-, receptor, surface
chr14_+_59628381 2.170 NM_022495
C14orf135
chromosome 14 open reading frame 135
chr20_+_3749164 2.168 NM_018347
C20orf29
chromosome 20 open reading frame 29
chr12_-_10657397 2.165 NM_018048
MAGOHB
mago-nashi homolog B (Drosophila)
chr1_-_119484733 2.160 NM_015836
NM_201263
WARS2

tryptophanyl tRNA synthetase 2, mitochondrial

chr4_-_120595218 2.132


chr6_-_26393705 2.130 NM_003543
HIST1H4H
histone cluster 1, H4h
chr6_-_3102690 2.114 NM_001069
TUBB2A
tubulin, beta 2A
chr16_+_18986417 2.111 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr3_-_101077605 2.064 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr1_+_36462625 2.056 THRAP3
thyroid hormone receptor associated protein 3
chr14_+_34521854 2.045 NM_001146282
NM_003136
SRP54

signal recognition particle 54kDa

chr17_+_44325127 2.032 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr4_-_170770111 2.028 NM_012224
NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr17_-_46298671 2.013 TOB1
transducer of ERBB2, 1
chr2_-_202353898 2.006 ALS2
amyotrophic lateral sclerosis 2 (juvenile)
chr12_+_105692466 2.006 NM_018157
RIC8B
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
chr20_+_51023159 1.992 TSHZ2
teashirt zinc finger homeobox 2
chr16_+_18986721 1.991 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr2_-_54051290 1.990 NM_014614
PSME4
proteasome (prosome, macropain) activator subunit 4
chr3_+_186483408 1.980 LOC100505749
MAP3K13
hypothetical LOC100505749
mitogen-activated protein kinase kinase kinase 13
chr6_+_26312758 1.963 NM_003545
HIST1H4E
histone cluster 1, H4e
chr2_-_234317362 1.948 NM_001001394
DNAJB3
DnaJ (Hsp40) homolog, subfamily B, member 3
chr7_-_140270749 1.947 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr11_-_124871258 1.911 NM_005103
NM_022549
FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr5_-_89861048 1.884 NM_198273
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr6_-_34772565 1.873 NM_022758
NM_024294
C6orf106

chromosome 6 open reading frame 106

chr1_+_149247519 1.866 NM_021222
PRUNE
prune homolog (Drosophila)
chr20_-_5539487 1.864 NM_019593
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr19_-_10202947 1.855 NM_004230
S1PR2
sphingosine-1-phosphate receptor 2
chr6_-_30289092 1.835 NM_003449
TRIM26
tripartite motif containing 26
chr4_-_148824585 1.834 NM_138364
PRMT10
protein arginine methyltransferase 10 (putative)
chr6_-_17814596 1.810 NM_005124
NUP153
nucleoporin 153kDa
chr17_-_39556535 1.807 NM_001015053
NM_005474
HDAC5

histone deacetylase 5

chr3_+_101462375 1.796 NM_018309
TBC1D23
TBC1 domain family, member 23
chr1_+_232575850 1.789 NM_001012985
C1orf31
chromosome 1 open reading frame 31
chr17_-_68819713 1.786 NM_012121
CDC42EP4
CDC42 effector protein (Rho GTPase binding) 4
chr17_+_25828546 1.778 NM_001007024
NM_001007025
NM_004871
GOSR1


golgi SNAP receptor complex member 1


chr6_+_89848229 1.776 PNRC1
proline-rich nuclear receptor coactivator 1
chr6_-_34772495 1.771 C6orf106
chromosome 6 open reading frame 106
chr17_-_39556483 1.769 HDAC5
histone deacetylase 5
chr6_-_38715567 1.740 BTBD9
BTB (POZ) domain containing 9
chr2_+_108769572 1.726 NM_144978
CCDC138
coiled-coil domain containing 138
chr2_-_68332985 1.701 NM_000945
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr6_+_116798791 1.697 NM_013352
DSE
dermatan sulfate epimerase
chr16_-_47201588 1.695 NM_153029
N4BP1
NEDD4 binding protein 1
chr8_+_17148755 1.675 NM_001145152
NM_152415
VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

chr16_+_68938264 1.674 NM_018332
DDX19A
DEAD (Asp-Glu-Ala-As) box polypeptide 19A
chr1_-_159413833 1.666 NM_003779
B4GALT3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr17_-_8092078 1.642 CTC1
CTS telomere maintenance complex component 1
chr3_+_12573513 1.636 NM_014160
MKRN2
makorin ring finger protein 2
chr16_-_85146181 1.634 NM_001159380
NM_001159377
NM_001159378
NM_001159379
NM_022764
MTHFSD




methenyltetrahydrofolate synthetase domain containing




chr3_+_171558188 1.632 SKIL
SKI-like oncogene
chr4_+_144654526 1.628


chr20_+_254205 1.627 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr19_-_52308848 1.609 NM_015168
ZC3H4
zinc finger CCCH-type containing 4
chr4_+_144654005 1.609 NM_003601
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr9_-_168913 1.595 NM_001145355
NM_001145356
NM_018491
CBWD2
CBWD1


COBW domain containing 2
COBW domain containing 1


chr16_+_70437394 1.591 NM_001137675
ATXN1L
ataxin 1-like
chr6_-_15356865 1.590


chr15_-_58558410 1.585 NM_001018089
NM_024611
NARG2

NMDA receptor regulated 2

chr3_+_171558215 1.579 SKIL
SKI-like oncogene
chr3_+_158026769 1.578 NM_001004316
NM_001193283
LEKR1

leucine, glutamate and lysine rich 1

chr1_+_70649451 1.576 NM_001190463
NM_001902
NM_153742
CTH


cystathionase (cystathionine gamma-lyase)


chr2_-_202354139 1.570 NM_001135745
NM_020919
ALS2

amyotrophic lateral sclerosis 2 (juvenile)

chr17_-_50854054 1.567 NM_012329
MMD
monocyte to macrophage differentiation-associated
chr2_+_113911737 1.541 NM_172003
CBWD2
CBWD1
COBW domain containing 2
COBW domain containing 1
chr9_-_68552337 1.539 NM_001085457
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6
chr20_+_30161173 1.536 TM9SF4
transmembrane 9 superfamily protein member 4
chr20_-_48163071 1.536 NM_001032288
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr3_+_151608673 1.513 TSC22D2
TSC22 domain family, member 2
chr21_-_29286982 1.491 NM_015565
LTN1
listerin E3 ubiquitin protein ligase 1
chr6_-_27222556 1.486 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr17_+_15843832 1.484 TTC19
tetratricopeptide repeat domain 19
chr9_+_70046658 1.479 NM_201453
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6
chr15_-_49817090 1.475 LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr2_-_202353818 1.472


chr2_+_74539039 1.469 NM_012477
WBP1
WW domain binding protein 1
chr1_+_161027115 1.464 NM_016371
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7
chr4_-_104338924 1.454 NM_001813
CENPE
centromere protein E, 312kDa
chr1_+_40399618 1.451 NM_012421
RLF
rearranged L-myc fusion
chr2_+_105727836 1.445 NM_001004722
NM_003581
NCK2

NCK adaptor protein 2

chr2_-_27566024 1.441 NM_015662
IFT172
intraflagellar transport 172 homolog (Chlamydomonas)
chr1_-_36636044 1.440 NM_032881
LSM10
LSM10, U7 small nuclear RNA associated
chr3_+_52694975 1.438 NM_014366
NM_206825
NM_206826
GNL3


guanine nucleotide binding protein-like 3 (nucleolar)


chr16_+_15950707 1.436 NM_004996
NM_019862
NM_019898
NM_019899
NM_019900
ABCC1




ATP-binding cassette, sub-family C (CFTR/MRP), member 1




chr10_+_112247614 1.436 NM_004419
DUSP5
dual specificity phosphatase 5
chr4_-_186584031 1.433 NM_018359
UFSP2
UFM1-specific peptidase 2
chr9_-_93917458 1.429 NM_006415
NM_178324
SPTLC1

serine palmitoyltransferase, long chain base subunit 1

chr6_+_49539049 1.413 NM_018132
CENPQ
centromere protein Q
chr15_-_53487748 1.413 NM_004748
NM_020739
CCPG1

cell cycle progression 1

chr14_+_101855836 1.407 NM_018335
ZNF839
zinc finger protein 839
chr16_+_29880842 1.403 NM_001083613
NM_194280
TMEM219

transmembrane protein 219

chr3_-_102888090 1.395 NM_000986
RPL24
ribosomal protein L24
chr16_-_11744103 1.389 NM_015914
TXNDC11
thioredoxin domain containing 11
chr12_-_56111054 1.387 R3HDM2
R3H domain containing 2
chr19_-_9510257 1.386 NM_024106
ZNF426
zinc finger protein 426
chr15_+_70553719 1.376 NM_005744
ARIH1
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
chr20_+_57948803 1.376 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr7_+_127015650 1.368 NM_001662
ARF5
ADP-ribosylation factor 5
chr3_+_186786655 1.365 NM_021627
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr1_+_40399642 1.359 RLF
rearranged L-myc fusion
chr14_-_23781607 1.354 NM_001099274
NM_012461
TINF2

TERF1 (TRF1)-interacting nuclear factor 2

chr3_-_122951200 1.348 NM_004487
GOLGB1
golgin B1
chr19_+_40183169 1.339 GRAMD1A
GRAM domain containing 1A
chr1_-_149247464 1.337 NM_001163258
NM_018379
FAM63A

family with sequence similarity 63, member A

chr9_+_101623957 1.324 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr11_-_66367279 1.323


chr15_+_70553743 1.320 ARIH1
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
chr17_-_34235078 1.314 NM_017748
CWC25
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr10_+_85889164 1.313 NM_014394
GHITM
growth hormone inducible transmembrane protein
chr6_-_38715613 1.310 BTBD9
BTB (POZ) domain containing 9
chr8_+_128875902 1.307 PVT1
Pvt1 oncogene (non-protein coding)
chr2_-_156897286 1.301 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr4_+_153676857 1.300 DKFZP434I0714
hypothetical protein DKFZP434I0714
chr17_+_33761234 1.294 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr2_+_30523586 1.283 NM_182551
NM_001002257
LCLAT1

lysocardiolipin acyltransferase 1

chr2_-_202215593 1.283 NM_152388
ALS2CR4
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4
chr9_-_6005602 1.279 NM_012416
RANBP6
RAN binding protein 6
chr16_+_66855827 1.277 NM_001076785
NM_003983
SLC7A6

solute carrier family 7 (cationic amino acid transporter, y+ system), member 6

chr1_+_55219052 1.272 NM_182532
TMEM61
transmembrane protein 61
chr16_-_20819061 1.266 NM_173475
DCUN1D3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr16_+_20819488 1.252 NM_001128301
NM_001128302
LYRM1

LYR motif containing 1

chr3_+_43303005 1.224 NM_001100594
NM_017719
SNRK

SNF related kinase

chr12_+_70519753 1.219 NM_001146213
NM_001146214
NM_022771
TBC1D15


TBC1 domain family, member 15


chr6_+_35335278 1.216 ZNF76
zinc finger protein 76
chr12_-_56452144 1.215 NM_005371
NM_023033
METTL1

methyltransferase like 1

chr15_+_48503860 1.213 NM_001128610
NM_001128611
NM_005154
USP8


ubiquitin specific peptidase 8


chr2_+_170149348 1.211 PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr9_+_132990834 1.207 NUP214
nucleoporin 214kDa
chr1_+_32443822 1.200 NM_001160042
NM_018134
IQCC

IQ motif containing C

chr2_+_190014403 1.199 NM_032168
WDR75
WD repeat domain 75
chr16_-_72959492 1.193 LOC283922
pyruvate dehydrogenase phosphatase regulatory subunit pseudogene
chr8_-_95343716 1.188 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr6_+_30137014 1.181 NM_014596
NM_170783
ZNRD1

zinc ribbon domain containing 1

chr6_-_30136734 1.181 ZNRD1-AS1
ZNRD1 antisense RNA 1 (non-protein coding)
chr2_-_144806508 1.179 NM_001164629
GTDC1
glycosyltransferase-like domain containing 1
chr17_-_46553083 1.176 NM_001130528
NM_003971
SPAG9

sperm associated antigen 9

chr3_+_150330060 1.168 NM_032383
HPS3
Hermansky-Pudlak syndrome 3
chr16_-_83602620 1.162 NM_001145548
NM_017740
ZDHHC7

zinc finger, DHHC-type containing 7

chr15_+_36533595 1.161 NM_001042429
NM_173611
FAM98B

family with sequence similarity 98, member B

chr16_-_83602587 1.158 ZDHHC7
zinc finger, DHHC-type containing 7
chr2_-_144806498 1.157 GTDC1
glycosyltransferase-like domain containing 1
chr11_-_62363551 1.155 WDR74
WD repeat domain 74
chr1_-_58938323 1.153 NM_001085487
MYSM1
Myb-like, SWIRM and MPN domains 1
chr17_-_45110339 1.141 NM_001007226
NM_001007227
NM_001007228
NM_001007229
NM_001007230
NM_003563
SPOP





speckle-type POZ protein





chr2_-_25047988 1.140 DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr20_-_34835546 1.137 NM_001145316
NM_024918
NM_001145315
NM_001145317
NM_001145318
DSN1




DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)




chr9_+_124066973 1.133 MRRF
mitochondrial ribosome recycling factor
chr20_-_25625173 1.128 NM_015655
ZNF337
zinc finger protein 337
chr2_-_25048276 1.118 NM_001198559
NM_016544
DNAJC27

DnaJ (Hsp40) homolog, subfamily C, member 27

chr9_+_103200939 1.116 NM_003452
NM_197977
ZNF189

zinc finger protein 189

chr1_+_36462583 1.115 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr7_-_93471463 1.115 NM_005868
BET1
blocked early in transport 1 homolog (S. cerevisiae)
chr11_+_66952462 1.111 NM_003952
RPS6KB2
ribosomal protein S6 kinase, 70kDa, polypeptide 2
chr1_-_35879619 1.106 PSMB2
proteasome (prosome, macropain) subunit, beta type, 2
chr17_-_632135 1.104 NM_016080
GLOD4
glyoxalase domain containing 4
chr2_-_240613357 1.104 NDUFA10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr19_-_15351523 1.094 NM_005858
AKAP8
A kinase (PRKA) anchor protein 8
chr19_-_52426055 1.092 NM_014417
BBC3
BCL2 binding component 3
chr17_-_39447817 1.089 NM_032376
TMEM101
transmembrane protein 101
chr20_+_33823318 1.084 NM_016436
PHF20
PHD finger protein 20
chr9_+_115023684 1.075 SLC31A1
solute carrier family 31 (copper transporters), member 1
chr6_+_35335212 1.075 ZNF76
zinc finger protein 76
chr7_+_55987046 1.074 NM_015969
MRPS17
mitochondrial ribosomal protein S17
chr10_+_21863099 1.072 NM_001195627
NM_001195628
NM_001195630
NM_004641
MLLT10



myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10



chr3_+_102775716 1.058 NM_020357
PCNP
PEST proteolytic signal containing nuclear protein
chr11_+_66367458 1.053 NM_001032279
NM_005133
RCE1

RCE1 homolog, prenyl protein peptidase (S. cerevisiae)

chr3_-_53356573 1.049 NM_018403
DCP1A
DCP1 decapping enzyme homolog A (S. cerevisiae)
chr16_-_27187549 1.049 NSMCE1
non-SMC element 1 homolog (S. cerevisiae)
chr8_-_95343696 1.046 GEM
GTP binding protein overexpressed in skeletal muscle
chr2_+_170149092 1.045 NM_004792
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr3_+_184898234 1.044 NM_018023
YEATS2
YEATS domain containing 2
chr2_-_216944911 1.042 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr14_+_30161285 1.041 SCFD1
sec1 family domain containing 1
chr15_-_47235057 1.041 NM_001143887
NM_004236
COPS2

COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)

chr18_+_11841388 1.041 NM_020412
CHMP1B
chromatin modifying protein 1B
chr2_-_75280121 1.038 NM_001058
NM_015727
TACR1

tachykinin receptor 1

chr1_+_226741665 1.037 NM_001010858
RNF187
ring finger protein 187

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.38 8.07e-20 GO:0044237 cellular metabolic process
1.48 1.29e-18 GO:0044260 cellular macromolecule metabolic process
1.29 1.19e-14 GO:0008152 metabolic process
1.38 6.94e-14 GO:0043170 macromolecule metabolic process
1.31 2.70e-13 GO:0044238 primary metabolic process
1.53 6.90e-12 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.46 2.60e-11 GO:0006807 nitrogen compound metabolic process
1.47 4.39e-11 GO:0034641 cellular nitrogen compound metabolic process
1.57 3.02e-10 GO:0090304 nucleic acid metabolic process
1.97 4.69e-09 GO:0022402 cell cycle process
1.83 8.62e-09 GO:0007049 cell cycle
1.63 1.11e-08 GO:0006996 organelle organization
1.76 1.91e-08 GO:0044248 cellular catabolic process
2.04 5.59e-08 GO:0006396 RNA processing
1.46 1.71e-07 GO:0044267 cellular protein metabolic process
2.23 3.59e-07 GO:0000279 M phase
1.56 5.38e-07 GO:0016070 RNA metabolic process
1.94 5.62e-07 GO:0022403 cell cycle phase
1.61 8.83e-07 GO:0009056 catabolic process
2.07 1.01e-06 GO:0016071 mRNA metabolic process
2.07 1.20e-06 GO:0044265 cellular macromolecule catabolic process
1.49 1.26e-05 GO:0010467 gene expression
2.35 1.42e-05 GO:0008380 RNA splicing
1.93 2.14e-05 GO:0000278 mitotic cell cycle
2.14 3.61e-05 GO:0006397 mRNA processing
1.88 4.79e-05 GO:0009057 macromolecule catabolic process
1.76 6.75e-05 GO:0046907 intracellular transport
2.26 1.04e-04 GO:0000087 M phase of mitotic cell cycle
3.04 1.19e-04 GO:0006403 RNA localization
3.03 2.10e-04 GO:0050657 nucleic acid transport
3.03 2.10e-04 GO:0050658 RNA transport
3.03 2.10e-04 GO:0051236 establishment of RNA localization
2.53 2.15e-04 GO:0000375 RNA splicing, via transesterification reactions
1.82 3.10e-04 GO:0051276 chromosome organization
2.53 3.20e-04 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.53 3.20e-04 GO:0000398 nuclear mRNA splicing, via spliceosome
3.08 4.43e-04 GO:0051028 mRNA transport
1.10 5.26e-04 GO:0009987 cellular process
2.19 7.28e-04 GO:0000280 nuclear division
2.19 7.28e-04 GO:0007067 mitosis
1.29 7.48e-04 GO:0071840 cellular component organization or biogenesis
2.12 7.57e-04 GO:0043632 modification-dependent macromolecule catabolic process
2.08 1.06e-03 GO:0044257 cellular protein catabolic process
1.33 1.19e-03 GO:0071841 cellular component organization or biogenesis at cellular level
2.08 1.40e-03 GO:0051603 proteolysis involved in cellular protein catabolic process
2.10 1.50e-03 GO:0019941 modification-dependent protein catabolic process
2.71 1.67e-03 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.12 1.90e-03 GO:0048285 organelle fission
2.09 1.97e-03 GO:0006511 ubiquitin-dependent protein catabolic process
1.39 2.24e-03 GO:0043412 macromolecule modification
1.30 2.64e-03 GO:0019538 protein metabolic process
1.63 2.65e-03 GO:0033554 cellular response to stress
2.29 2.96e-03 GO:0009261 ribonucleotide catabolic process
1.49 3.14e-03 GO:0033036 macromolecule localization
1.40 3.29e-03 GO:0006464 protein modification process
1.28 3.49e-03 GO:0016043 cellular component organization
1.73 3.50e-03 GO:0051726 regulation of cell cycle
1.42 3.86e-03 GO:0009059 macromolecule biosynthetic process
2.03 4.01e-03 GO:0009259 ribonucleotide metabolic process
1.42 4.49e-03 GO:0034645 cellular macromolecule biosynthetic process
1.31 6.10e-03 GO:0071842 cellular component organization at cellular level
2.25 6.22e-03 GO:0009154 purine ribonucleotide catabolic process
1.95 6.42e-03 GO:0034622 cellular macromolecular complex assembly
3.91 7.24e-03 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
2.02 7.57e-03 GO:0009150 purine ribonucleotide metabolic process
2.62 8.01e-03 GO:0048193 Golgi vesicle transport
1.95 8.39e-03 GO:0030163 protein catabolic process
2.23 1.03e-02 GO:0009203 ribonucleoside triphosphate catabolic process
2.23 1.03e-02 GO:0009207 purine ribonucleoside triphosphate catabolic process
3.45 1.11e-02 GO:0031124 mRNA 3'-end processing
2.22 1.15e-02 GO:0009146 purine nucleoside triphosphate catabolic process
1.77 1.19e-02 GO:0006974 response to DNA damage stimulus
2.10 1.57e-02 GO:0009166 nucleotide catabolic process
2.14 1.61e-02 GO:0006195 purine nucleotide catabolic process
2.19 1.61e-02 GO:0009143 nucleoside triphosphate catabolic process
1.31 1.71e-02 GO:0009058 biosynthetic process
1.31 2.03e-02 GO:0044249 cellular biosynthetic process
1.56 2.10e-02 GO:0045184 establishment of protein localization
1.77 2.58e-02 GO:0006325 chromatin organization
1.97 2.70e-02 GO:0009141 nucleoside triphosphate metabolic process
1.75 2.73e-02 GO:0034621 cellular macromolecular complex subunit organization
2.09 2.99e-02 GO:0072523 purine-containing compound catabolic process
1.90 3.12e-02 GO:0010564 regulation of cell cycle process
1.98 3.23e-02 GO:0009144 purine nucleoside triphosphate metabolic process
1.44 3.44e-02 GO:0051641 cellular localization
3.07 3.51e-02 GO:0031123 RNA 3'-end processing
1.46 3.59e-02 GO:0031325 positive regulation of cellular metabolic process
1.48 4.16e-02 GO:0008104 protein localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 1.69e-31 GO:0044424 intracellular part
1.22 4.13e-30 GO:0005622 intracellular
1.31 2.06e-28 GO:0043231 intracellular membrane-bounded organelle
1.31 3.28e-28 GO:0043227 membrane-bounded organelle
1.25 1.30e-23 GO:0043229 intracellular organelle
1.25 1.47e-23 GO:0043226 organelle
1.40 6.52e-20 GO:0005634 nucleus
1.40 1.27e-19 GO:0044446 intracellular organelle part
1.75 2.23e-19 GO:0044428 nuclear part
1.39 4.93e-19 GO:0044422 organelle part
1.26 1.86e-17 GO:0005737 cytoplasm
1.77 7.10e-17 GO:0031981 nuclear lumen
1.67 2.01e-16 GO:0070013 intracellular organelle lumen
1.65 1.63e-15 GO:0043233 organelle lumen
1.63 4.10e-15 GO:0031974 membrane-enclosed lumen
1.84 1.96e-13 GO:0005654 nucleoplasm
1.29 2.89e-11 GO:0044444 cytoplasmic part
1.41 4.97e-11 GO:0032991 macromolecular complex
1.48 1.41e-07 GO:0005829 cytosol
1.36 1.55e-06 GO:0043234 protein complex
1.92 2.48e-05 GO:0005730 nucleolus
1.84 6.58e-05 GO:0005694 chromosome
2.79 1.50e-04 GO:0005681 spliceosomal complex
1.67 5.13e-04 GO:0044451 nucleoplasm part
1.82 1.15e-03 GO:0044427 chromosomal part
1.30 1.41e-03 GO:0043228 non-membrane-bounded organelle
1.30 1.41e-03 GO:0043232 intracellular non-membrane-bounded organelle
3.07 3.44e-03 GO:0071013 catalytic step 2 spliceosome
1.32 7.37e-03 GO:0031090 organelle membrane
1.70 8.06e-03 GO:0030529 ribonucleoprotein complex
2.09 8.09e-03 GO:0016604 nuclear body
2.24 4.99e-02 GO:0000775 chromosome, centromeric region

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.23 2.76e-10 GO:0005515 protein binding
1.93 1.28e-09 GO:0003723 RNA binding
1.42 2.73e-06 GO:0000166 nucleotide binding
1.10 3.56e-06 GO:0005488 binding
1.32 7.42e-06 GO:0003676 nucleic acid binding
1.22 4.10e-05 GO:0003824 catalytic activity
1.43 7.87e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.40 2.57e-04 GO:0032553 ribonucleotide binding
1.40 2.57e-04 GO:0032555 purine ribonucleotide binding
1.39 3.81e-04 GO:0017076 purine nucleotide binding
2.02 2.19e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.41 3.10e-03 GO:0005524 ATP binding
2.11 5.33e-03 GO:0019787 small conjugating protein ligase activity
1.39 7.27e-03 GO:0032559 adenyl ribonucleotide binding
2.00 9.30e-03 GO:0016881 acid-amino acid ligase activity
1.38 9.82e-03 GO:0030554 adenyl nucleotide binding
1.54 1.35e-02 GO:0016462 pyrophosphatase activity
1.54 1.57e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.55 1.65e-02 GO:0017111 nucleoside-triphosphatase activity
3.31 1.69e-02 GO:0004221 ubiquitin thiolesterase activity
1.53 1.83e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
2.06 2.00e-02 GO:0004842 ubiquitin-protein ligase activity