Motif ID: EHF.p2

Z-value: 3.404


Transcription factors associated with EHF.p2:

Gene SymbolEntrez IDGene Name
EHF 26298 ets homologous factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EHFchr11_+_34599227-0.234.0e-01Click!


Activity profile for motif EHF.p2.

activity profile for motif EHF.p2


Sorted Z-values histogram for motif EHF.p2

Sorted Z-values for motif EHF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EHF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_19636918 4.822 NM_001012991
C16orf88
chromosome 16 open reading frame 88
chr20_+_16658608 4.809 NM_003092
NM_198220
SNRPB2

small nuclear ribonucleoprotein polypeptide B

chr14_+_34831294 3.832 NM_002791
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr14_+_34831355 3.800 PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr6_+_111409933 3.487 NM_032194
RPF2
ribosome production factor 2 homolog (S. cerevisiae)
chr20_+_33750645 3.286 NM_080748
ROMO1
reactive oxygen species modulator 1
chr17_-_44377094 3.280 NM_007241
SNF8
SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
chr14_+_34521945 3.151 SRP54
signal recognition particle 54kDa
chr2_-_27147995 3.135 NM_001134693
OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr14_-_38709161 3.119 NM_001079537
NM_177452
TRAPPC6B

trafficking protein particle complex 6B

chr1_-_234834410 3.090 NM_018072
HEATR1
HEAT repeat containing 1
chr14_+_23771464 3.061 NM_001002000
NM_001002001
GMPR2

guanosine monophosphate reductase 2

chr16_+_8799170 3.060 NM_000303
PMM2
phosphomannomutase 2
chr14_-_21049204 3.049 NM_019852
METTL3
methyltransferase like 3
chr14_+_34521854 3.048 NM_001146282
NM_003136
SRP54

signal recognition particle 54kDa

chr20_+_43478120 2.988 NM_001184728
NM_001184729
NM_001184730
NM_015937
PIGT



phosphatidylinositol glycan anchor biosynthesis, class T



chr9_-_124733599 2.951 NM_020924
ZBTB26
zinc finger and BTB domain containing 26
chr20_-_33750457 2.944 NM_001198989
NM_021100
NFS1

NFS1 nitrogen fixation 1 homolog (S. cerevisiae)

chr2_+_220170804 2.936 NM_052902
STK11IP
serine/threonine kinase 11 interacting protein
chr15_+_32304477 2.884 NM_016454
TMEM85
transmembrane protein 85
chr5_-_159778621 2.879 NM_006425
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr12_-_64810768 2.824 NM_032338
LLPH
LLP homolog, long-term synaptic facilitation (Aplysia)
chr1_-_28842103 2.821 NM_001135218
NM_005644
TAF12

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

chr7_-_44496703 2.771 NM_015332
NUDCD3
NudC domain containing 3
chr2_-_37047113 2.743 NM_003162
STRN
striatin, calmodulin binding protein
chr14_-_20807346 2.740 NM_001077442
NM_001077443
NM_004500
NM_031314
HNRNPC



heterogeneous nuclear ribonucleoprotein C (C1/C2)



chr20_-_2592777 2.740 NM_006899
NM_174855
NM_174856
IDH3B


isocitrate dehydrogenase 3 (NAD+) beta


chr2_-_43676603 2.732 NM_001083953
NM_022065
THADA

thyroid adenoma associated

chr12_+_67366989 2.713 NM_020401
NUP107
nucleoporin 107kDa
chr2_-_99319197 2.710 NM_005783
TXNDC9
thioredoxin domain containing 9
chr2_-_152740387 2.703 NM_005843
STAM2
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr2_+_176842368 2.663 NM_006554
MTX2
metaxin 2
chr2_+_122124034 2.603 LOC254128
hypothetical LOC254128
chr14_-_23781607 2.581 NM_001099274
NM_012461
TINF2

TERF1 (TRF1)-interacting nuclear factor 2

chr12_+_118590039 2.572 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr2_-_45691887 2.513 NM_018079
SRBD1
S1 RNA binding domain 1
chr20_+_29598848 2.500 HM13
histocompatibility (minor) 13
chr7_+_107171809 2.476 CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr11_+_8660913 2.474 RPL27A
ribosomal protein L27a
chr6_+_30142910 2.455 NM_021959
PPP1R11
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr14_-_23781328 2.455 TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr16_+_11978002 2.444 NM_032167
RUNDC2A
RUN domain containing 2A
chr6_-_49538810 2.395 NM_000255
MUT
methylmalonyl CoA mutase
chr12_-_48248132 2.370 NM_006337
MCRS1
microspherule protein 1
chr16_-_8798973 2.342 NM_015421
TMEM186
transmembrane protein 186
chr17_+_43328514 2.341 NM_003110
SP2
Sp2 transcription factor
chr17_-_53950191 2.340 NM_004687
MTMR4
myotubularin related protein 4
chr20_+_60395515 2.331 NM_001024
RPS21
ribosomal protein S21
chr2_-_122210873 2.325 NM_032390
MKI67IP
MKI67 (FHA domain) interacting nucleolar phosphoprotein
chr2_+_118562499 2.325 NM_016133
INSIG2
insulin induced gene 2
chr21_+_36614347 2.320 NM_015358
MORC3
MORC family CW-type zinc finger 3
chr6_-_166675980 2.292 NM_145169
SFT2D1
SFT2 domain containing 1
chr20_-_29774258 2.290 NM_001191
NM_138578
BCL2L1

BCL2-like 1

chr18_-_70415788 2.265 LOC400657
hypothetical LOC400657
chr8_-_95634845 2.216 NM_015496
NM_183009
KIAA1429

KIAA1429

chr1_+_23990228 2.216 NM_007260
LYPLA2
lysophospholipase II
chr2_+_69974581 2.189 NM_006857
SNRNP27
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr14_+_23771942 2.187 NM_001002002
NM_016576
GMPR2

guanosine monophosphate reductase 2

chr6_-_166676016 2.171 SFT2D1
SFT2 domain containing 1
chr7_-_91713044 2.160 NM_004912
NM_001013406
NM_194454
KRIT1


KRIT1, ankyrin repeat containing


chr14_+_22368942 2.151 MRPL52
mitochondrial ribosomal protein L52
chr1_+_42896634 2.125 NM_006347
PPIH
peptidylprolyl isomerase H (cyclophilin H)
chr6_-_116488458 2.089 NM_002031
FRK
fyn-related kinase
chr14_-_30996348 2.078 NM_080664
C14orf126
HEATR5A
chromosome 14 open reading frame 126
HEAT repeat containing 5A
chr6_-_28663045 2.058 NM_052923
SCAND3
SCAN domain containing 3
chr19_+_63022879 2.057 LOC100293516
zinc finger protein
chr1_-_19192 2.041 WASH1
WASH3P
WASH2P
WASH7P
WAS protein family homolog 1
WAS protein family homolog 3 pseudogene
WAS protein family homolog 2 pseudogene
WAS protein family homolog 7 pseudogene
chr7_+_7646840 2.039 LOC729852
hypothetical LOC729852
chr6_-_28212532 2.009 LOC100129195
hypothetical LOC100129195
chr20_+_49008754 2.007 NM_014484
MOCS3
molybdenum cofactor synthesis 3
chr2_-_54051290 2.005 NM_014614
PSME4
proteasome (prosome, macropain) activator subunit 4
chr2_+_138975946 1.976


chr17_-_53282376 1.950 NM_016070
MRPS23
mitochondrial ribosomal protein S23
chr7_+_99451110 1.950 NM_003439
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr8_-_22582526 1.930 NM_018688
BIN3
bridging integrator 3
chr17_-_38229790 1.908 NM_003766
BECN1
beclin 1, autophagy related
chr2_+_128565269 1.904 UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr14_-_23771401 1.897 NM_006156
NEDD8
neural precursor cell expressed, developmentally down-regulated 8
chr20_-_17986520 1.869 NM_021220
OVOL2
ovo-like 2 (Drosophila)
chr2_+_217071764 1.868 NM_000998
RPL37A
ribosomal protein L37a
chr14_+_22368923 1.868 NM_178336
NM_180982
NM_181304
NM_181305
NM_181306
NM_181307
MRPL52





mitochondrial ribosomal protein L52





chr17_-_55511056 1.853 NM_022070
HEATR6
HEAT repeat containing 6
chr10_-_15942461 1.850 NM_024948
FAM188A
family with sequence similarity 188, member A
chr19_+_57492236 1.848 NM_144684
ZNF480
zinc finger protein 480
chr16_-_23559978 1.822 NM_024675
PALB2
partner and localizer of BRCA2
chr1_-_247086686 1.810 NM_030645
SH3BP5L
SH3-binding domain protein 5-like
chr2_-_201082978 1.796 NM_152387
KCTD18
potassium channel tetramerisation domain containing 18
chr13_+_44937025 1.783 NM_031431
COG3
component of oligomeric golgi complex 3
chr12_+_49080858 1.769 NM_001170803
NM_001170804
NM_001170808
NM_052879
NM_199188
NM_199190
LARP4





La ribonucleoprotein domain family, member 4





chr16_-_23371952 1.756 NM_153603
COG7
component of oligomeric golgi complex 7
chr16_-_70400040 1.751 AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr7_-_99517128 1.745 NM_017715
NM_032924
ZNF3

zinc finger protein 3

chr20_+_60395623 1.744 RPS21
ribosomal protein S21
chr16_-_74024750 1.742 NM_006324
CFDP1
craniofacial development protein 1
chr6_-_31618203 1.738 NM_004640
NM_080598
DDX39B

DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B

chr14_+_30161267 1.735 NM_016106
NM_182835
SCFD1

sec1 family domain containing 1

chr2_+_65308332 1.731 NM_001005386
NM_005722
ACTR2

ARP2 actin-related protein 2 homolog (yeast)

chr5_+_148705169 1.731 NM_152407
GRPEL2
GrpE-like 2, mitochondrial (E. coli)
chr2_+_113058470 1.724 NM_032309
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr14_+_49157150 1.723 NM_002408
MGAT2
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr20_+_1047216 1.723 NM_006814
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr20_-_5879036 1.711 NM_015939
TRMT6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr6_-_31617704 1.703 DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr10_-_96112609 1.694 NM_022451
NOC3L
nucleolar complex associated 3 homolog (S. cerevisiae)
chr4_+_84596141 1.693 NM_016067
MRPS18C
mitochondrial ribosomal protein S18C
chr17_-_39447817 1.690 NM_032376
TMEM101
transmembrane protein 101
chr16_-_31427130 1.685 NM_022744
C16orf58
chromosome 16 open reading frame 58
chr20_+_23279372 1.685 NM_013248
NXT1
NTF2-like export factor 1
chr10_+_89254202 1.677 NM_001178117
NM_004897
MINPP1

multiple inositol-polyphosphate phosphatase 1

chr16_+_76690664 1.655 NM_016373
NM_130791
NM_130844
WWOX


WW domain containing oxidoreductase


chr13_-_25694343 1.654 NM_005977
RNF6
ring finger protein (C3H2C3 type) 6
chr2_+_128565222 1.643 NM_020120
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr6_+_57290357 1.642 NM_000947
PRIM2
primase, DNA, polypeptide 2 (58kDa)
chr20_-_34005799 1.639 NM_016558
NM_033630
SCAND1

SCAN domain containing 1

chr13_+_28131140 1.637 NM_015932
POMP
proteasome maturation protein
chr13_+_28131279 1.621 POMP
proteasome maturation protein
chr20_+_3138055 1.620 NM_033453
NM_181493
ITPA

inosine triphosphatase (nucleoside triphosphate pyrophosphatase)

chr17_+_63144500 1.601 NM_015462
NOL11
nucleolar protein 11
chr3_+_120700057 1.595 NM_016589
C3orf1
chromosome 3 open reading frame 1
chr5_+_74098828 1.592 NM_014886
NSA2
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr20_+_35351428 1.587 NM_001003897
NM_022077
MANBAL

mannosidase, beta A, lysosomal-like

chr17_-_30929669 1.586 NM_000286
PEX12
peroxisomal biogenesis factor 12
chr2_+_201099093 1.586 NM_001160033
NM_001160046
NM_152524
SGOL2


shugoshin-like 2 (S. pombe)


chr20_+_35351473 1.583 MANBAL
mannosidase, beta A, lysosomal-like
chr14_-_23981493 1.577 NM_020195
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr17_-_40122542 1.570 NM_001099225
NM_144609
CCDC43

coiled-coil domain containing 43

chr4_+_110956360 1.569 GAR1
GAR1 ribonucleoprotein homolog (yeast)
chr12_-_119116848 1.564 NM_006836
GCN1L1
GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
chr20_-_47965393 1.551 SPATA2
spermatogenesis associated 2
chr2_+_102401580 1.548 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr18_+_19337437 1.540 NM_013326
C18orf8
chromosome 18 open reading frame 8
chr2_-_74915722 1.531


chr12_-_104153920 1.529 NM_018171
APPL2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr4_-_84595967 1.526 NM_133636
HELQ
helicase, POLQ-like
chr14_-_23771399 1.512 NEDD8
neural precursor cell expressed, developmentally down-regulated 8
chr12_+_122652572 1.496 NM_020936
DDX55
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
chr20_-_44575599 1.495 NM_018102
NM_199441
ZNF334

zinc finger protein 334

chr6_+_33276580 1.495 NM_001077516
NM_006979
SLC39A7

solute carrier family 39 (zinc transporter), member 7

chr8_+_82807218 1.488 NM_152284
CHMP4C
chromatin modifying protein 4C
chr1_+_84717507 1.488 NM_025065
RPF1
ribosome production factor 1 homolog (S. cerevisiae)
chr2_-_68332985 1.487 NM_000945
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr20_-_44751542 1.484 NM_033550
TP53RK
TP53 regulating kinase
chr5_-_70621688 1.480 SMA4
glucuronidase, beta pseudogene
chr19_-_21943 1.473 WASH1
WASH3P
WASH5P
WAS protein family homolog 1
WAS protein family homolog 3 pseudogene
WAS protein family homolog 5 pseudogene
chr1_+_39229474 1.466 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr2_-_27739947 1.463 NM_014860
SUPT7L
suppressor of Ty 7 (S. cerevisiae)-like
chr1_+_167603817 1.462 NM_003666
BLZF1
basic leucine zipper nuclear factor 1
chr17_-_26257341 1.452 NM_024683
C17orf42
chromosome 17 open reading frame 42
chr14_+_30098079 1.444 NM_017769
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr2_-_44442447 1.443 NM_001171603
NM_001171617
PREPL

prolyl endopeptidase-like

chr20_+_29790564 1.439 NM_012112
TPX2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr4_+_119825983 1.435 NM_020961
METTL14
methyltransferase like 14
chr3_+_181802592 1.432 NM_001042601
NM_133462
TTC14

tetratricopeptide repeat domain 14

chr6_-_34963565 1.430 NM_005643
TAF11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
chr2_-_178125680 1.427 NM_152517
TTC30B
tetratricopeptide repeat domain 30B
chr5_+_132230214 1.423 NM_014402
UQCRQ
ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
chr3_-_130362563 1.416 NM_020701
ISY1
ISY1 splicing factor homolog (S. cerevisiae)
chr20_-_47965443 1.406 SPATA2
spermatogenesis associated 2
chr14_-_23771312 1.404 NEDD8
neural precursor cell expressed, developmentally down-regulated 8
chr17_-_76883677 1.402 NM_001037984
NM_138570
SLC38A10

solute carrier family 38, member 10

chr6_-_84994032 1.402 NM_014895
KIAA1009
KIAA1009
chr3_-_69183926 1.402 NM_007114
TMF1
TATA element modulatory factor 1
chr16_-_70400232 1.402 AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr11_+_109805799 1.400 NM_004109
FDX1
ferredoxin 1
chr11_+_65576379 1.395 NM_006842
SF3B2
splicing factor 3b, subunit 2, 145kDa
chr6_-_31617748 1.390 DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr2_-_131567458 1.389 NM_001009993
FAM168B
family with sequence similarity 168, member B
chr2_+_138438277 1.379 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr2_+_232359303 1.378 NM_022730
COPS7B
COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis)
chr14_+_74249599 1.372 NM_015962
FCF1
FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)
chr14_+_23982017 1.369


chr2_+_108432008 1.360 NM_181453
GCC2
GRIP and coiled-coil domain containing 2
chr2_+_32244406 1.358 NM_001193513
NM_001193514
NM_001193515
NM_017964
SLC30A6



solute carrier family 30 (zinc transporter), member 6



chr20_-_34005619 1.358 SCAND1
SCAN domain containing 1
chr14_+_60858151 1.349 NM_006255
PRKCH
protein kinase C, eta
chr2_-_148494732 1.347 NM_001190882
NM_001190879
NM_002552
NM_001190881
NM_181741
ORC4




origin recognition complex, subunit 4




chr5_+_134122359 1.337 NM_014829
DDX46
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr15_+_89274413 1.333 NM_001039675
UNC45A
unc-45 homolog A (C. elegans)
chr3_+_102763369 1.333 NM_017819
RG9MTD1
RNA (guanine-9-) methyltransferase domain containing 1
chr5_+_90711887 1.331 LOC100129716
hypothetical LOC100129716
chr3_-_197714762 1.319 NM_152617
RNF168
ring finger protein 168
chr8_+_30133354 1.315 NM_006571
DCTN6
dynactin 6
chr2_+_100985122 1.314 NM_000993
NM_001098577
NM_001099693
RPL31


ribosomal protein L31


chr20_-_49008445 1.313 NM_003859
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr17_+_32380287 1.309 NM_012138
AATF
apoptosis antagonizing transcription factor
chr6_+_170705345 1.307 NM_001172085
NM_003194
TBP

TATA box binding protein

chr14_+_34413157 1.300


chr9_+_128662756 1.299 NM_001099270
ZBTB34
zinc finger and BTB domain containing 34
chr3_-_130600931 1.298 RPL32P3
ribosomal protein L32 pseudogene 3
chr20_+_60191455 1.285 NM_015666
GTPBP5
GTP binding protein 5 (putative)
chr2_+_108432097 1.285 GCC2
GRIP and coiled-coil domain containing 2
chr20_-_47965474 1.282 NM_006038
SPATA2
spermatogenesis associated 2
chr2_+_202838725 1.279 NM_015934
NOP58
NOP58 ribonucleoprotein homolog (yeast)
chr11_-_101828563 1.279 NM_052932
TMEM123
transmembrane protein 123
chr2_+_55600220 1.275 NM_080667
CCDC104
coiled-coil domain containing 104
chr1_+_44451698 1.269 NM_001034023
NM_001034024
NM_019100
DMAP1


DNA methyltransferase 1 associated protein 1


chr14_-_22127954 1.267 NM_001344
DAD1
defender against cell death 1
chr20_+_18217120 1.265 NM_001083330
NM_003434
ZNF133

zinc finger protein 133

chr6_-_170735593 1.262 NM_002598
NM_144781
PDCD2

programmed cell death 2

chr20_+_5679032 1.262 NM_152504
C20orf196
chromosome 20 open reading frame 196

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.38 1.83e-29 GO:0044260 cellular macromolecule metabolic process
1.32 9.80e-25 GO:0043170 macromolecule metabolic process
1.57 5.47e-22 GO:0010467 gene expression
1.43 1.80e-19 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.48 2.65e-19 GO:0090304 nucleic acid metabolic process
1.55 8.68e-19 GO:0016070 RNA metabolic process
1.23 5.33e-17 GO:0044237 cellular metabolic process
1.87 2.46e-15 GO:0006396 RNA processing
1.94 1.32e-14 GO:0016071 mRNA metabolic process
1.39 2.85e-14 GO:0044267 cellular protein metabolic process
1.20 2.36e-13 GO:0044238 primary metabolic process
1.18 5.64e-13 GO:0008152 metabolic process
2.03 2.71e-12 GO:0006397 mRNA processing
1.99 3.82e-12 GO:0016032 viral reproduction
1.31 4.90e-12 GO:0034641 cellular nitrogen compound metabolic process
1.34 1.22e-11 GO:0071841 cellular component organization or biogenesis at cellular level
1.30 1.38e-11 GO:0006807 nitrogen compound metabolic process
2.11 8.35e-11 GO:0008380 RNA splicing
2.39 8.70e-11 GO:0022613 ribonucleoprotein complex biogenesis
1.43 1.70e-10 GO:0009059 macromolecule biosynthetic process
1.43 2.12e-10 GO:0034645 cellular macromolecule biosynthetic process
1.27 3.33e-10 GO:0071840 cellular component organization or biogenesis
1.43 6.55e-10 GO:0006996 organelle organization
1.54 6.55e-10 GO:0008104 protein localization
2.27 2.06e-09 GO:0071843 cellular component biogenesis at cellular level
1.59 2.40e-09 GO:0015031 protein transport
2.02 2.69e-09 GO:0006412 translation
2.29 3.13e-09 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.29 3.13e-09 GO:0000398 nuclear mRNA splicing, via spliceosome
1.31 3.50e-09 GO:0071842 cellular component organization at cellular level
1.58 4.39e-09 GO:0045184 establishment of protein localization
2.27 4.52e-09 GO:0000375 RNA splicing, via transesterification reactions
1.28 8.94e-09 GO:0019538 protein metabolic process
1.25 4.65e-08 GO:0016043 cellular component organization
1.57 1.23e-07 GO:0046907 intracellular transport
2.80 2.92e-07 GO:0071826 ribonucleoprotein complex subunit organization
1.63 3.82e-07 GO:0009057 macromolecule catabolic process
1.40 1.23e-06 GO:0033036 macromolecule localization
2.35 1.69e-06 GO:0048193 Golgi vesicle transport
2.76 2.73e-06 GO:0022618 ribonucleoprotein complex assembly
1.65 3.58e-06 GO:0044265 cellular macromolecule catabolic process
1.65 5.41e-06 GO:0006974 response to DNA damage stimulus
1.76 1.25e-05 GO:0030163 protein catabolic process
1.87 1.27e-05 GO:0032446 protein modification by small protein conjugation
1.48 1.76e-05 GO:0033554 cellular response to stress
1.78 1.94e-05 GO:0070647 protein modification by small protein conjugation or removal
1.89 2.48e-05 GO:0016567 protein ubiquitination
1.62 2.69e-05 GO:0034613 cellular protein localization
1.77 2.76e-05 GO:0044257 cellular protein catabolic process
1.61 4.06e-05 GO:0070727 cellular macromolecule localization
1.37 4.10e-05 GO:0051641 cellular localization
1.77 4.52e-05 GO:0051603 proteolysis involved in cellular protein catabolic process
1.61 9.26e-05 GO:0034621 cellular macromolecular complex subunit organization
1.94 9.51e-05 GO:0033365 protein localization to organelle
1.75 1.13e-04 GO:0019941 modification-dependent protein catabolic process
2.59 1.52e-04 GO:0006354 transcription elongation, DNA-dependent
1.74 1.58e-04 GO:0043632 modification-dependent macromolecule catabolic process
1.75 1.84e-04 GO:0006511 ubiquitin-dependent protein catabolic process
1.44 2.34e-04 GO:0043933 macromolecular complex subunit organization
2.20 2.53e-04 GO:0042254 ribosome biogenesis
1.65 3.02e-04 GO:0006886 intracellular protein transport
1.40 3.67e-04 GO:0032774 RNA biosynthetic process
1.37 3.99e-04 GO:0051649 establishment of localization in cell
2.23 8.71e-04 GO:0032984 macromolecular complex disassembly
2.23 8.71e-04 GO:0034623 cellular macromolecular complex disassembly
1.37 9.98e-04 GO:0007049 cell cycle
1.07 1.03e-03 GO:0009987 cellular process
2.50 1.03e-03 GO:0006353 transcription termination, DNA-dependent
1.23 1.39e-03 GO:0044249 cellular biosynthetic process
2.36 1.47e-03 GO:0030330 DNA damage response, signal transduction by p53 class mediator
1.43 1.77e-03 GO:0016192 vesicle-mediated transport
1.97 1.84e-03 GO:0010498 proteasomal protein catabolic process
1.97 1.84e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.26 2.02e-03 GO:0043412 macromolecule modification
2.17 2.61e-03 GO:0042770 signal transduction in response to DNA damage
1.47 2.85e-03 GO:0051726 regulation of cell cycle
1.22 3.13e-03 GO:0009058 biosynthetic process
2.03 3.40e-03 GO:0019058 viral infectious cycle
2.37 4.11e-03 GO:0031575 mitotic cell cycle G1/S transition checkpoint
2.37 4.11e-03 GO:0071779 G1/S transition checkpoint
2.58 4.21e-03 GO:0006368 transcription elongation from RNA polymerase II promoter
1.25 4.43e-03 GO:0006464 protein modification process
2.33 4.48e-03 GO:2000045 regulation of G1/S transition of mitotic cell cycle
1.94 4.60e-03 GO:0022415 viral reproductive process
2.29 4.81e-03 GO:0006415 translational termination
2.51 5.01e-03 GO:0071158 positive regulation of cell cycle arrest
2.45 5.79e-03 GO:0072594 establishment of protein localization to organelle
2.30 6.13e-03 GO:0019080 viral genome expression
2.30 6.13e-03 GO:0019083 viral transcription
2.20 7.10e-03 GO:0043241 protein complex disassembly
2.20 7.10e-03 GO:0043624 cellular protein complex disassembly
2.17 7.29e-03 GO:0006414 translational elongation
1.97 1.11e-02 GO:0007005 mitochondrion organization
1.76 1.31e-02 GO:0009146 purine nucleoside triphosphate catabolic process
2.68 1.35e-02 GO:0050434 positive regulation of viral transcription
1.74 1.45e-02 GO:0009261 ribonucleotide catabolic process
1.31 1.95e-02 GO:0044248 cellular catabolic process
2.37 2.01e-02 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
1.73 2.18e-02 GO:0009143 nucleoside triphosphate catabolic process
1.37 2.18e-02 GO:0022402 cell cycle process
1.65 2.22e-02 GO:0010608 posttranscriptional regulation of gene expression
2.44 2.27e-02 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.44 2.27e-02 GO:0072395 signal transduction involved in cell cycle checkpoint
2.44 2.27e-02 GO:0072401 signal transduction involved in DNA integrity checkpoint
2.44 2.27e-02 GO:0072404 signal transduction involved in G1/S transition checkpoint
2.44 2.27e-02 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
2.44 2.27e-02 GO:0072422 signal transduction involved in DNA damage checkpoint
2.44 2.27e-02 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.44 2.27e-02 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
1.74 2.36e-02 GO:0009203 ribonucleoside triphosphate catabolic process
1.74 2.36e-02 GO:0009207 purine ribonucleoside triphosphate catabolic process
2.23 2.46e-02 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.63 2.62e-02 GO:0006366 transcription from RNA polymerase II promoter
1.27 2.69e-02 GO:0009056 catabolic process
2.49 3.53e-02 GO:0046782 regulation of viral transcription
1.29 3.94e-02 GO:0044085 cellular component biogenesis
2.26 4.04e-02 GO:0000209 protein polyubiquitination
1.73 4.16e-02 GO:0006605 protein targeting
2.12 4.50e-02 GO:0006352 transcription initiation, DNA-dependent
1.70 4.53e-02 GO:0009154 purine ribonucleotide catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 1.95e-48 GO:0005622 intracellular
1.19 1.26e-47 GO:0044424 intracellular part
1.21 1.58e-40 GO:0043229 intracellular organelle
1.21 3.99e-40 GO:0043226 organelle
1.24 1.46e-39 GO:0043231 intracellular membrane-bounded organelle
1.24 3.40e-39 GO:0043227 membrane-bounded organelle
1.32 9.13e-31 GO:0005634 nucleus
1.29 4.15e-25 GO:0044446 intracellular organelle part
1.52 7.34e-24 GO:0044428 nuclear part
1.28 2.12e-23 GO:0044422 organelle part
1.57 7.89e-23 GO:0031981 nuclear lumen
1.48 4.39e-22 GO:0031974 membrane-enclosed lumen
1.48 3.60e-21 GO:0070013 intracellular organelle lumen
1.47 8.01e-21 GO:0043233 organelle lumen
2.04 6.75e-19 GO:0030529 ribonucleoprotein complex
1.16 1.79e-15 GO:0005737 cytoplasm
1.54 2.18e-14 GO:0005654 nucleoplasm
1.29 9.95e-14 GO:0032991 macromolecular complex
1.20 9.50e-13 GO:0044444 cytoplasmic part
1.30 1.90e-10 GO:0043228 non-membrane-bounded organelle
1.30 1.90e-10 GO:0043232 intracellular non-membrane-bounded organelle
1.68 1.15e-07 GO:0005730 nucleolus
2.33 3.99e-07 GO:0005681 spliceosomal complex
2.64 5.44e-06 GO:0071013 catalytic step 2 spliceosome
1.28 8.16e-06 GO:0005829 cytosol
1.99 1.94e-05 GO:0005840 ribosome
1.87 3.97e-05 GO:0016604 nuclear body
2.20 4.34e-05 GO:0016607 nuclear speck
1.47 4.53e-05 GO:0044451 nucleoplasm part
1.04 1.19e-04 GO:0044464 cell part
1.04 1.25e-04 GO:0005623 cell
1.20 1.80e-04 GO:0043234 protein complex
1.93 2.85e-03 GO:0000151 ubiquitin ligase complex
1.28 3.50e-03 GO:0005739 mitochondrion
3.08 5.34e-03 GO:0030532 small nuclear ribonucleoprotein complex
1.32 6.56e-03 GO:0005794 Golgi apparatus
2.34 1.35e-02 GO:0015934 large ribosomal subunit
2.43 1.54e-02 GO:0005798 Golgi-associated vesicle
1.20 1.60e-02 GO:0031090 organelle membrane
1.46 1.71e-02 GO:0005768 endosome
2.17 2.11e-02 GO:0022626 cytosolic ribosome
1.40 2.35e-02 GO:0005694 chromosome
2.27 2.52e-02 GO:0000502 proteasome complex
2.15 2.78e-02 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
1.59 3.50e-02 GO:0010008 endosome membrane
2.79 4.34e-02 GO:0030660 Golgi-associated vesicle membrane
1.57 4.55e-02 GO:0044440 endosomal part
2.60 4.57e-02 GO:0030120 vesicle coat
1.68 4.95e-02 GO:0005819 spindle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 4.61e-15 GO:0005515 protein binding
1.32 1.06e-14 GO:0003676 nucleic acid binding
1.69 7.44e-14 GO:0003723 RNA binding
1.09 1.71e-10 GO:0005488 binding
1.87 7.59e-05 GO:0004842 ubiquitin-protein ligase activity
1.84 7.75e-05 GO:0019787 small conjugating protein ligase activity
2.05 1.15e-04 GO:0003735 structural constituent of ribosome
1.75 2.17e-04 GO:0016881 acid-amino acid ligase activity
1.66 1.24e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.23 1.85e-03 GO:0008270 zinc ion binding
2.28 2.71e-03 GO:0008135 translation factor activity, nucleic acid binding
1.20 8.00e-03 GO:0003677 DNA binding
1.46 1.72e-02 GO:0016874 ligase activity
1.19 2.07e-02 GO:0000166 nucleotide binding
1.99 2.30e-02 GO:0008026 ATP-dependent helicase activity
1.99 2.30e-02 GO:0070035 purine NTP-dependent helicase activity