Motif ID: FOXA2.p3

Z-value: 1.405


Transcription factors associated with FOXA2.p3:

Gene SymbolEntrez IDGene Name
FOXA2 3170 forkhead box A2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXA2chr20_-_22512893-0.449.2e-02Click!


Activity profile for motif FOXA2.p3.

activity profile for motif FOXA2.p3


Sorted Z-values histogram for motif FOXA2.p3

Sorted Z-values for motif FOXA2.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXA2.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_110890719 1.881 NM_001100388
NM_207430
C11orf88

chromosome 11 open reading frame 88

chr6_-_32227695 1.485 NM_030651
PRRT1
proline-rich transmembrane protein 1
chr5_+_149960820 1.391 NM_001166208
SYNPO
synaptopodin
chr9_-_111230926 1.372 NM_001145371
NM_001145372
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr1_+_150753601 1.366 NM_019060
CRCT1
cysteine-rich C-terminal 1
chr1_-_120155581 1.329 NM_001159352
NM_001159353
NM_032044
REG4


regenerating islet-derived family, member 4


chr6_-_32227645 1.305 PRRT1
proline-rich transmembrane protein 1
chr4_-_152368492 1.256 SH3D19
SH3 domain containing 19
chr1_-_229627412 1.229 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr12_+_123339662 1.182 NM_181709
FAM101A
family with sequence similarity 101, member A
chr18_+_59405513 1.176 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr1_-_67039518 1.166 NM_005478
INSL5
insulin-like 5
chr5_+_145296313 1.046 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr1_+_13784553 1.006 NM_001006624
NM_001006625
PDPN

podoplanin

chr2_-_101457596 1.005 NM_001145664
RFX8
regulatory factor X, 8
chr7_+_116238309 0.987 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr11_-_6746763 0.962 NM_001004490
OR2AG2
olfactory receptor, family 2, subfamily AG, member 2
chr2_-_171725604 0.930 NM_012290
TLK1
tousled-like kinase 1
chr7_+_28305464 0.920 NM_182899
CREB5
cAMP responsive element binding protein 5
chr11_+_124294355 0.894 NM_001037558
HEPN1
hepatocellular carcinoma, down-regulated 1
chr16_+_68516401 0.894 NM_199424
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr12_+_32578513 0.883 FGD4
FYVE, RhoGEF and PH domain containing 4
chr1_+_171871283 0.863 NM_001195190
LOC730159
hypothetical protein LOC730159
chr3_+_137224266 0.855 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr5_-_36337756 0.855 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr2_+_108590032 0.849 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chr7_+_142850667 0.845 NM_177437
TAS2R60
taste receptor, type 2, member 60
chr4_+_120029426 0.807 NM_001128933
NM_001128934
NM_133477
SYNPO2


synaptopodin 2


chr1_+_24518398 0.802 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr2_+_173394560 0.777 NM_001100397
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr3_+_176059763 0.767 NM_207015
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr8_+_12847521 0.764 NM_020844
KIAA1456
KIAA1456
chr13_+_77007809 0.759 NM_001160706
NM_003843
NM_144777
SCEL


sciellin


chr1_+_198263352 0.757 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr1_-_150079656 0.752 NM_001136003
C2CD4D
C2 calcium-dependent domain containing 4D
chr9_-_4142182 0.747 NM_152629
GLIS3
GLIS family zinc finger 3
chr1_+_205344200 0.745 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr6_-_26038817 0.741 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr1_-_150599105 0.739 NM_001014342
FLG2
filaggrin family member 2
chr1_+_176577228 0.736 NM_004841
RASAL2
RAS protein activator like 2
chr8_-_134141586 0.734 NM_006748
SLA
Src-like-adaptor
chrX_+_135558001 0.732 NM_000074
CD40LG
CD40 ligand
chr10_+_18729518 0.728 NM_201570
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr3_+_188197029 0.723


chr6_-_159386007 0.718 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr1_-_177106702 0.708 NM_004673
ANGPTL1
angiopoietin-like 1
chr12_+_27740694 0.705 NM_001029874
REP15
RAB15 effector protein
chr7_+_129693938 0.684 NM_001869
CPA2
carboxypeptidase A2 (pancreatic)
chr2_+_38009405 0.678 NM_001170792
FAM82A1
family with sequence similarity 82, member A1
chr2_-_87102453 0.676 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr8_-_81155564 0.666 NM_001025252
TPD52
tumor protein D52
chr1_+_24522116 0.662 NM_021180
GRHL3
grainyhead-like 3 (Drosophila)
chr7_+_116151411 0.662 MET
met proto-oncogene (hepatocyte growth factor receptor)
chr15_+_94670160 0.653 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr2_-_134042500 0.649 NM_207363
NM_207481
NCKAP5

NCK-associated protein 5

chr4_-_186693574 0.649 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr1_-_150564302 0.640 NM_002016
FLG
filaggrin
chrX_-_10761729 0.629 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr11_-_107087943 0.628 NM_003063
SLN
sarcolipin
chr17_-_58237742 0.614 NM_001100875
MARCH10
membrane-associated ring finger (C3HC4) 10
chr11_-_117640078 0.609


chr1_+_200018380 0.596 NAV1
neuron navigator 1
chr17_-_74361975 0.596 TIMP2
TIMP metallopeptidase inhibitor 2
chr15_+_66711380 0.582 NM_001190457
CORO2B
coronin, actin binding protein, 2B
chr16_+_52027020 0.581 RBL2
retinoblastoma-like 2 (p130)
chr17_+_3326045 0.578 NM_000049
ASPA
aspartoacylase
chr1_+_15351585 0.576 NM_001136216
NM_001136217
TMEM51

transmembrane protein 51

chr7_+_94377145 0.573 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory (inhibitor) subunit 9A


chr21_+_29439768 0.573 C21orf7
chromosome 21 open reading frame 7
chr12_-_102968044 0.570 NM_031302
GLT8D2
glycosyltransferase 8 domain containing 2
chr4_+_14950657 0.565 NM_001135170
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr2_-_20390601 0.565 NM_015317
PUM2
pumilio homolog 2 (Drosophila)
chrX_-_15243647 0.557 NM_080873
ASB11
ankyrin repeat and SOCS box containing 11
chr1_+_169747788 0.555 PRRC2C
proline-rich coiled-coil 2C
chr10_+_51219558 0.554 NM_002443
NM_138634
MSMB

microseminoprotein, beta-

chr12_-_55614311 0.550 NM_148897
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr3_-_150569574 0.548 TM4SF1
transmembrane 4 L six family member 1
chr8_-_25338472 0.547 NM_000825
NM_001083111
GNRH1

gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)

chr1_+_204484081 0.540 NM_001910
NM_148964
CTSE

cathepsin E

chr14_+_20429382 0.535 NM_002935
RNASE2
RNASE3
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
ribonuclease, RNase A family, 3
chr1_+_170656450 0.534 NM_139240
C1orf105
chromosome 1 open reading frame 105
chr4_-_152316105 0.532 NM_001128924
SH3D19
SH3 domain containing 19
chr18_+_50646616 0.526 NM_004163
RAB27B
RAB27B, member RAS oncogene family
chr10_-_21847126 0.526


chr12_+_5473558 0.522 NM_002527
NTF3
neurotrophin 3
chr4_+_14985272 0.520 NM_001135171
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr14_+_54238581 0.516 SAMD4A
sterile alpha motif domain containing 4A
chr7_-_27102049 0.516 NM_005522
NM_153620
HOXA1

homeobox A1

chr5_-_58607673 0.509 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_-_7487989 0.507 NM_174941
CD163L1
CD163 molecule-like 1
chr1_+_34997928 0.506 NM_153212
GJB4
gap junction protein, beta 4, 30.3kDa
chr3_+_195336625 0.506 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr11_-_27679617 0.504 NM_170733
BDNF
brain-derived neurotrophic factor
chr12_+_21570457 0.498 NM_030572
C12orf39
chromosome 12 open reading frame 39
chr11_+_55407348 0.496 NM_032681
SPRYD5
SPRY domain containing 5
chr3_-_191650291 0.493 NM_207316
TMEM207
transmembrane protein 207
chr3_+_173954940 0.485 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr3_-_115380539 0.476 NM_000796
NM_033663
DRD3

dopamine receptor D3

chr6_-_89984214 0.475 NM_002042
GABRR1
gamma-aminobutyric acid (GABA) receptor, rho 1
chr3_-_150993299 0.474 NM_001144960
C3orf16
chromosome 3 open reading frame 16
chrX_+_135441970 0.471 NM_016267
VGLL1
vestigial like 1 (Drosophila)
chr7_+_142723340 0.466 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr21_+_38550739 0.464 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr17_-_36418869 0.464 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr11_-_57792206 0.463 NM_207374
OR10W1
olfactory receptor, family 10, subfamily W, member 1
chr2_+_11591692 0.463 NM_014668
GREB1
growth regulation by estrogen in breast cancer 1
chr2_-_69033515 0.460 NM_182536
GKN2
gastrokine 2
chr8_-_108579270 0.459 NM_001146
ANGPT1
angiopoietin 1
chr12_+_53534565 0.457 NM_058173
MUCL1
mucin-like 1
chr14_-_76612286 0.455


chr6_+_74462654 0.454 CD109
CD109 molecule
chr16_+_29697090 0.447 ZG16
zymogen granule protein 16 homolog (rat)
chr1_+_40486159 0.447 NM_001008740
TMCO2
transmembrane and coiled-coil domains 2
chr1_+_15351885 0.447 TMEM51
transmembrane protein 51
chr15_-_68128924 0.444 TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr3_+_38322430 0.443 NM_004803
SLC22A14
solute carrier family 22, member 14
chr1_-_115039614 0.441 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr6_-_136829705 0.439 NM_001198615
MAP7
microtubule-associated protein 7
chr5_-_13997588 0.436 NM_001369
DNAH5
dynein, axonemal, heavy chain 5
chr11_+_120478584 0.436 NM_005422
TECTA
tectorin alpha
chr6_+_134800533 0.436 LOC154092
hypothetical LOC154092
chr15_+_60146467 0.432 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr14_-_20636909 0.431 NM_001101672
ZNF219
zinc finger protein 219
chr1_-_201586910 0.431 NM_002023
FMOD
fibromodulin
chr12_-_102967828 0.428 GLT8D2
glycosyltransferase 8 domain containing 2
chr3_+_195336631 0.426 HES1
hairy and enhancer of split 1, (Drosophila)
chr7_+_123083096 0.425 NM_207163
LMOD2
leiomodin 2 (cardiac)
chr10_+_124310170 0.422 NM_004406
NM_007329
NM_017579
DMBT1


deleted in malignant brain tumors 1


chr12_+_9925354 0.421 NM_001190765
KLRF2
killer cell lectin-like receptor subfamily F, member 2
chr17_-_36074812 0.421 NM_152349
KRT222
keratin 222
chr18_-_50777634 0.414 NM_025214
CCDC68
coiled-coil domain containing 68
chr1_-_57204208 0.414 NM_000066
C8B
complement component 8, beta polypeptide
chr7_+_80069439 0.414 NM_001001547
CD36
CD36 molecule (thrombospondin receptor)
chr12_-_68379331 0.414 NM_032735
BEST3
bestrophin 3
chr3_+_23904086 0.412 UBE2E1
ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr11_-_9243408 0.412 NM_015213
DENND5A
DENN/MADD domain containing 5A
chr7_+_134226727 0.412 CALD1
caldesmon 1
chr5_+_125828685 0.411 NM_001146322
GRAMD3
GRAM domain containing 3
chr11_+_55776251 0.410 NM_001004747
OR5T3
olfactory receptor, family 5, subfamily T, member 3
chrX_+_10084984 0.409 NM_001830
CLCN4
chloride channel 4
chr22_+_19458378 0.408 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr2_-_21081694 0.407 APOB
apolipoprotein B (including Ag(x) antigen)
chr3_-_71715431 0.406 NM_001012505
NM_032682
FOXP1

forkhead box P1

chr11_-_4555625 0.405 NM_144663
C11orf40
chromosome 11 open reading frame 40
chr20_+_9406460 0.404 PLCB4
phospholipase C, beta 4
chr5_+_102229425 0.404 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr4_+_159662349 0.400 NM_021634
RXFP1
relaxin/insulin-like family peptide receptor 1
chr14_-_93859394 0.400 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr6_+_144227265 0.399 NM_001013623
C6orf94
chromosome 6 open reading frame 94
chr12_-_14929991 0.399 NM_000900
NM_001190839
MGP

matrix Gla protein

chr11_+_109468734 0.399 ZC3H12C
zinc finger CCCH-type containing 12C
chr6_-_112682573 0.394 LAMA4
laminin, alpha 4
chr2_+_113601616 0.394 IL1RN
interleukin 1 receptor antagonist
chr8_-_93099040 0.389 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_-_125843092 0.385 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr8_-_125785611 0.385 MTSS1
metastasis suppressor 1
chr12_-_119249938 0.385 NM_000928
PLA2G1B
phospholipase A2, group IB (pancreas)
chr6_+_74462485 0.384 CD109
CD109 molecule
chr15_-_48198697 0.379 NM_024837
ATP8B4
ATPase, class I, type 8B, member 4
chr12_-_10464308 0.379 NM_002261
NM_007333
KLRC3

killer cell lectin-like receptor subfamily C, member 3

chr17_-_36409632 0.379 NM_031959
KRTAP3-2
keratin associated protein 3-2
chrX_-_48655978 0.378 PIM2
pim-2 oncogene
chr1_-_20682541 0.377


chr4_-_40327396 0.374 RBM47
RNA binding motif protein 47
chr11_+_5714253 0.370 NM_001005180
OR56B1
olfactory receptor, family 56, subfamily B, member 1
chr5_-_16561936 0.369 NM_019000
FAM134B
family with sequence similarity 134, member B
chr1_+_198278339 0.368 NR5A2
nuclear receptor subfamily 5, group A, member 2
chr7_+_89681069 0.363 NM_001040666
STEAP2
six transmembrane epithelial antigen of the prostate 2
chr3_+_99370233 0.362 NM_001005515
OR5H15
olfactory receptor, family 5, subfamily H, member 15
chr12_-_11066436 0.361 NM_176888
TAS2R19
taste receptor, type 2, member 19
chr7_+_47661366 0.360 NM_001123065
C7orf65
chromosome 7 open reading frame 65
chr2_-_55053398 0.359


chr1_+_218768423 0.358 MARK1
MAP/microtubule affinity-regulating kinase 1
chr6_+_74462630 0.354 CD109
CD109 molecule
chr3_+_173043832 0.353 NM_001164436
TMEM212
transmembrane protein 212
chr5_-_42847716 0.351 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr2_+_178893216 0.350 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr14_-_20636568 0.350 NM_016423
ZNF219
zinc finger protein 219
chr5_+_55182963 0.349 NM_139017
IL31RA
interleukin 31 receptor A
chr10_-_7699192 0.348 ITIH5
inter-alpha (globulin) inhibitor H5
chr8_+_21967008 0.348 NM_001114137
EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr8_-_95720870 0.348 LOC100288748
hypothetical LOC100288748
chr16_+_75790849 0.347 NM_001129979
SYCE1L
synaptonemal complex central element protein 1-like
chr10_-_129581192 0.344 NM_152311
CLRN3
clarin 3
chr4_-_100575313 0.343 NM_001166504
NM_000673
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr9_-_97319067 0.342 NM_001083602
NM_001083603
PTCH1

patched 1

chr2_+_201182187 0.341 AOX1
aldehyde oxidase 1
chrX_+_118598325 0.341 NM_181777
UBE2A
ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr17_-_36719030 0.340 NM_001146182
KRTAP16-1
keratin associated protein 16-1
chr7_+_134226690 0.340 NM_033139
NM_033140
CALD1

caldesmon 1

chr7_+_100037817 0.339 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr9_-_34700062 0.338 NM_002989
CCL21
chemokine (C-C motif) ligand 21
chr3_-_194579207 0.338 NM_198505
ATP13A5
ATPase type 13A5
chrX_+_47748677 0.333 NM_205856
SPACA5
sperm acrosome associated 5
chr5_+_92944680 0.332 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr10_-_75005421 0.331 NM_152586
USP54
ubiquitin specific peptidase 54
chr3_+_46628928 0.329 NM_001195442
LOC100132146
hypothetical LOC100132146
chr8_-_82606104 0.329 NM_001105281
FABP12
fatty acid binding protein 12
chr2_+_113601608 0.328 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr8_+_143758875 0.328 NM_005672
PSCA
prostate stem cell antigen

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.39 7.57e-08 GO:0007606 sensory perception of chemical stimulus
1.90 5.16e-06 GO:0007600 sensory perception
2.31 6.52e-06 GO:0007608 sensory perception of smell
1.19 1.03e-02 GO:0050896 response to stimulus
1.21 2.65e-02 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.32 4.80e-06 GO:0005886 plasma membrane
1.31 6.87e-06 GO:0071944 cell periphery
1.47 1.96e-05 GO:0005576 extracellular region
1.57 1.82e-03 GO:0044421 extracellular region part
1.62 6.59e-03 GO:0005615 extracellular space
1.17 1.26e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.89 8.05e-07 GO:0004930 G-protein coupled receptor activity
2.29 5.22e-06 GO:0004984 olfactory receptor activity
1.55 9.82e-06 GO:0004872 receptor activity
1.47 2.57e-05 GO:0004871 signal transducer activity
1.47 2.57e-05 GO:0060089 molecular transducer activity
1.61 5.86e-05 GO:0004888 transmembrane receptor activity