Motif ID: ZFP161.p2

Z-value: 1.879


Transcription factors associated with ZFP161.p2:

Gene SymbolEntrez IDGene Name
ZFP161 7541 zinc finger protein 161 homolog (mouse)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZFP161chr18_-_52860130.234.0e-01Click!


Activity profile for motif ZFP161.p2.

activity profile for motif ZFP161.p2


Sorted Z-values histogram for motif ZFP161.p2

Sorted Z-values for motif ZFP161.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZFP161.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_138726737 4.255 NM_152421
FAM69B
family with sequence similarity 69, member B
chr8_+_1937711 3.641 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr11_-_1549719 3.306 NM_004420
DUSP8
dual specificity phosphatase 8
chr22_-_27405708 3.090 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr2_-_233501069 3.025 NM_001114090
NGEF
neuronal guanine nucleotide exchange factor
chr3_+_128830656 2.684 NM_015720
PODXL2
podocalyxin-like 2
chr20_+_20296744 2.386 NM_002196
INSM1
insulinoma-associated 1
chr13_-_78075683 2.271 NM_006237
POU4F1
POU class 4 homeobox 1
chr10_-_725522 2.219 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr10_+_105027431 2.005 INA
internexin neuronal intermediate filament protein, alpha
chr20_-_538909 1.979 NM_004609
TCF15
transcription factor 15 (basic helix-loop-helix)
chr3_-_129689394 1.933 NM_001145662
GATA2
GATA binding protein 2
chr4_-_5945596 1.927 NM_001014809
CRMP1
collapsin response mediator protein 1
chr4_+_2031036 1.904 NM_178557
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chr20_-_61933012 1.892 ZBTB46
zinc finger and BTB domain containing 46
chr10_+_23521464 1.865 NM_178161
PTF1A
pancreas specific transcription factor, 1a
chr19_-_11452439 1.819 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chr16_-_27982277 1.813 NM_001109763
GSG1L
GSG1-like
chr22_-_37569679 1.789


chr13_+_99432258 1.704 NM_007129
ZIC2
Zic family member 2 (odd-paired homolog, Drosophila)
chr17_+_56832255 1.679 TBX2
T-box 2
chr1_-_11674264 1.675 NM_001127325
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chr21_+_33364420 1.671 OLIG1
oligodendrocyte transcription factor 1
chr4_-_110443247 1.671 NM_032518
NM_198721
COL25A1

collagen, type XXV, alpha 1

chr16_+_53915971 1.665 NM_024335
IRX6
iroquois homeobox 6
chr20_+_17155617 1.661 NM_002594
PCSK2
proprotein convertase subtilisin/kexin type 2
chr16_+_55180767 1.642 NM_005954
MT3
metallothionein 3
chr8_+_65656164 1.623 BHLHE22
basic helix-loop-helix family, member e22
chr17_-_34015631 1.585 NM_025248
SRCIN1
SRC kinase signaling inhibitor 1
chr16_-_695719 1.569 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chr11_-_30564338 1.565 NM_001145399
MPPED2
metallophosphoesterase domain containing 2
chr3_+_127743868 1.565 CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr20_+_17155669 1.556 PCSK2
proprotein convertase subtilisin/kexin type 2
chr22_+_47263919 1.556 NM_001082967
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr1_+_41022066 1.554 NM_004700
NM_172163
KCNQ4

potassium voltage-gated channel, KQT-like subfamily, member 4

chr11_+_627268 1.537 NM_000797
DRD4
dopamine receptor D4
chr21_+_33364316 1.525 NM_138983
OLIG1
oligodendrocyte transcription factor 1
chr18_-_21184824 1.524


chr2_+_104837004 1.507


chr9_-_34579679 1.499 NM_001842
NM_147164
CNTFR

ciliary neurotrophic factor receptor

chr10_+_115793795 1.486 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr16_+_54782802 1.479 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr14_+_104338423 1.477 ZBTB42
zinc finger and BTB domain containing 42
chr18_+_74841262 1.449 NM_171999
SALL3
sal-like 3 (Drosophila)
chr5_-_132976121 1.448 NM_015082
FSTL4
follistatin-like 4
chr14_+_91859289 1.446 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr7_-_44331544 1.444 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chr4_-_109308893 1.438 NM_001130713
NM_001130714
NM_016269
LEF1


lymphoid enhancer-binding factor 1


chr19_+_45799060 1.436 NM_001042545
LTBP4
latent transforming growth factor beta binding protein 4
chr8_-_125809831 1.426 NM_014751
MTSS1
metastasis suppressor 1
chr5_-_132976094 1.419 FSTL4
follistatin-like 4
chr17_+_41327808 1.415 MAPT
microtubule-associated protein tau
chr17_+_56831951 1.392 NM_005994
TBX2
T-box 2
chr3_-_9570412 1.368 NM_198560
LHFPL4
lipoma HMGIC fusion partner-like 4
chr6_-_5952631 1.367 NM_016588
NRN1
neuritin 1
chr7_-_72822471 1.353 NM_001306
CLDN3
claudin 3
chr14_+_68796621 1.348 GALNTL1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr19_-_18867868 1.347 NM_021267
NM_198207
NM_001492
LASS1

GDF1
LAG1 homolog, ceramide synthase 1

growth differentiation factor 1
chr19_-_5291700 1.324 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr16_+_65754788 1.306 NM_001040667
NM_001538
HSF4

heat shock transcription factor 4

chr10_+_60606352 1.305 NM_032439
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr13_-_27967215 1.303 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr7_+_45580704 1.297 ADCY1
adenylate cyclase 1 (brain)
chr13_-_71338144 1.294 DACH1
dachshund homolog 1 (Drosophila)
chr15_+_31390454 1.285 NM_001036
RYR3
ryanodine receptor 3
chr21_+_32167175 1.283 NM_014586
HUNK
hormonally up-regulated Neu-associated kinase
chr19_+_52215982 1.283 NM_002517
NPAS1
neuronal PAS domain protein 1
chr10_-_131652007 1.281 NM_001005463
EBF3
early B-cell factor 3
chr1_+_4614964 1.276 NM_001042478
NM_018836
AJAP1

adherens junctions associated protein 1

chr13_+_48692472 1.265 NM_001507
MLNR
motilin receptor
chr10_-_28074752 1.248 NM_173576
MKX
mohawk homeobox
chr4_+_48180033 1.247 NM_152679
SLC10A4
solute carrier family 10 (sodium/bile acid cotransporter family), member 4
chr17_+_56832492 1.240 TBX2
T-box 2
chr15_-_81113676 1.233 NM_030594
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr22_-_31784328 1.230 NM_001135774
SYN3
synapsin III
chrX_-_142549984 1.225 NM_001184750
SLITRK4
SLIT and NTRK-like family, member 4
chr18_-_29412148 1.224


chr11_-_69299351 1.217 NM_002007
FGF4
fibroblast growth factor 4
chr22_-_36245155 1.216 NM_014550
CARD10
caspase recruitment domain family, member 10
chr3_-_129694717 1.208 NM_032638
GATA2
GATA binding protein 2
chr11_-_63014986 1.207 NM_001146728
NM_001146729
NM_054108
HRASLS5


HRAS-like suppressor family, member 5


chr8_-_61356436 1.201 NM_004056
CA8
carbonic anhydrase VIII
chr1_+_11674365 1.189 NM_198545
C1orf187
chromosome 1 open reading frame 187
chr1_-_49014993 1.188 NM_024603
BEND5
BEN domain containing 5
chr8_+_104582151 1.186 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr5_+_76542461 1.185 NM_001029851
NM_001029852
NM_001029853
NM_001029854
NM_003719
PDE8B




phosphodiesterase 8B




chr18_+_13208777 1.181 NM_181481
NM_181482
C18orf1

chromosome 18 open reading frame 1

chr5_-_11956964 1.179 NM_001332
CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr9_+_70509925 1.170 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr17_-_16336204 1.168 NM_001113567
NM_207387
C17orf76

chromosome 17 open reading frame 76

chr1_-_1525309 1.159 LOC643988
hypothetical LOC643988
chr9_+_100745531 1.152 NM_001855
COL15A1
collagen, type XV, alpha 1
chr3_-_171786468 1.144 NM_020949
SLC7A14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr4_-_41848874 1.142 BEND4
BEN domain containing 4
chr8_-_37941970 1.140 ADRB3
adrenergic, beta-3-, receptor
chr20_+_17155680 1.139 PCSK2
proprotein convertase subtilisin/kexin type 2
chr14_+_103674812 1.137 NM_015656
KIF26A
kinesin family member 26A
chr10_+_83625049 1.136 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr17_+_41327662 1.131 MAPT
microtubule-associated protein tau
chr4_+_147779492 1.129 NM_004575
POU4F2
POU class 4 homeobox 2
chr4_+_4912272 1.113 NM_002448
MSX1
msh homeobox 1
chr14_+_99507848 1.103 EVL
Enah/Vasp-like
chr17_+_41327449 1.103 NM_001123066
NM_001123067
NM_005910
NM_016834
NM_016835
NM_016841
MAPT





microtubule-associated protein tau





chr16_+_54782751 1.099 NM_020988
NM_138736
GNAO1

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

chr1_-_215377718 1.088 NM_001134285
ESRRG
estrogen-related receptor gamma
chr10_+_94823221 1.087 NM_057157
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr2_+_171280944 1.086 SP5
Sp5 transcription factor
chr2_-_119632788 1.073 NM_182528
C1QL2
complement component 1, q subcomponent-like 2
chr16_+_25610847 1.072 NM_006040
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr2_+_112372671 1.065 MERTK
c-mer proto-oncogene tyrosine kinase
chr11_-_6396864 1.064 NM_001164
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr9_+_17568952 1.056 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr4_-_41849333 1.042 BEND4
BEN domain containing 4
chr5_+_75734759 1.039 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr12_+_2032649 1.025 NM_000719
NM_001129827
NM_001129829
NM_001129830
NM_001129831
NM_001129832
NM_001129833
NM_001129834
NM_001129835
NM_001129836
NM_001129837
NM_001129838
NM_001129839
NM_001129840
NM_001129841
NM_001129842
NM_001129843
NM_001129844
NM_001129846
NM_001167623
NM_001167624
NM_001167625
NM_199460
CACNA1C






















calcium channel, voltage-dependent, L type, alpha 1C subunit






















chr11_-_2248757 1.019 NM_005170
ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr10_-_131652364 1.016 EBF3
early B-cell factor 3
chr12_+_50271283 1.011 NM_014191
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr4_+_19864332 1.008 NM_004787
SLIT2
slit homolog 2 (Drosophila)
chr1_-_21850874 1.005 NM_001145658
RAP1GAP
RAP1 GTPase activating protein
chr2_-_42573980 1.002 KCNG3
potassium voltage-gated channel, subfamily G, member 3
chr13_-_26232777 1.000 NM_005288
GPR12
G protein-coupled receptor 12
chr14_-_62581656 0.999 NM_139318
NM_172375
KCNH5

potassium voltage-gated channel, subfamily H (eag-related), member 5

chr4_-_109307325 0.992 NM_001166119
LEF1
lymphoid enhancer-binding factor 1
chr17_+_4434582 0.984 NM_001114974
SMTNL2
smoothelin-like 2
chrX_-_34585287 0.972 NM_031442
TMEM47
transmembrane protein 47
chr2_-_39040981 0.969 LOC375196
hypothetical LOC375196
chr10_-_60606195 0.968


chr3_-_127558747 0.965 NM_014079
KLF15
Kruppel-like factor 15
chr11_-_33847834 0.964 LMO2
LIM domain only 2 (rhombotin-like 1)
chr19_-_7845325 0.960 NM_001190467
FLJ22184
hypothetical protein FLJ22184
chr19_+_47509274 0.960 NM_173633
TMEM145
transmembrane protein 145
chr4_+_158361185 0.958 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr12_+_93066370 0.958 NM_005761
PLXNC1
plexin C1
chr19_-_18868395 0.954 LASS1
LAG1 homolog, ceramide synthase 1
chr3_-_135097111 0.951 NM_016577
RAB6B
RAB6B, member RAS oncogene family
chr22_+_48951286 0.951 NM_001160300
NM_052839
PANX2

pannexin 2

chr14_+_73128162 0.947 NM_152331
ACOT4
acyl-CoA thioesterase 4
chr19_+_38979502 0.947 NM_001129994
NM_001129995
NM_024076
KCTD15


potassium channel tetramerisation domain containing 15


chr17_+_41327792 0.941 MAPT
microtubule-associated protein tau
chr3_+_129690735 0.935


chr8_-_125809559 0.930 MTSS1
metastasis suppressor 1
chr15_-_75711743 0.929 NM_032808
LINGO1
leucine rich repeat and Ig domain containing 1
chr22_+_42137955 0.928 NM_001044370
MPPED1
metallophosphoesterase domain containing 1
chr14_+_91859904 0.922 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr8_-_133561738 0.921 KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr8_+_1909437 0.911 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr7_+_154943466 0.911 NM_001427
EN2
engrailed homeobox 2
chr14_-_77034853 0.909 NM_182509
NM_199296
ISM2

isthmin 2 homolog (zebrafish)

chr8_-_144583718 0.905 NM_201589
MAFA
v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr16_+_1979959 0.904 NM_004209
SYNGR3
synaptogyrin 3
chr11_-_61441536 0.904 NM_013401
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr10_+_24023680 0.902 NM_001098500
KIAA1217
KIAA1217
chr17_+_8865547 0.900 NM_004822
NTN1
netrin 1
chr19_+_40325993 0.899 NM_022006
FXYD7
FXYD domain containing ion transport regulator 7
chr20_-_3097070 0.896 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr3_-_135096986 0.895 RAB6B
RAB6B, member RAS oncogene family
chr11_-_64268126 0.894 NM_001098671
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_-_110088330 0.889 NM_020809
ARHGAP20
Rho GTPase activating protein 20
chr1_+_154878498 0.887 BCAN
brevican
chr1_+_224803226 0.882 C1orf95
chromosome 1 open reading frame 95
chr2_-_47650973 0.877 NM_022055
KCNK12
potassium channel, subfamily K, member 12
chr14_+_69021149 0.870 NM_001161498
UPF0639
UPF0639 protein
chr2_-_238813284 0.870 HES6
hairy and enhancer of split 6 (Drosophila)
chrX_-_18282698 0.870 NM_006089
SCML2
sex comb on midleg-like 2 (Drosophila)
chr15_+_97462675 0.868 NM_015286
NM_145728
SYNM

synemin, intermediate filament protein

chr19_+_10392128 0.862 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr16_-_47873183 0.861 NM_004352
CBLN1
cerebellin 1 precursor
chr15_-_75711785 0.857 LINGO1
leucine rich repeat and Ig domain containing 1
chr4_+_72271218 0.855 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr10_-_104169458 0.852 PSD
pleckstrin and Sec7 domain containing
chr6_+_69401660 0.851 NM_001704
BAI3
brain-specific angiogenesis inhibitor 3
chr10_+_122206455 0.851 NM_001030059
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr13_+_112671497 0.849 MCF2L
MCF.2 cell line derived transforming sequence-like
chr5_-_83716346 0.848 NM_005711
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr11_-_2248374 0.847 ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr12_+_48641545 0.846 NM_001651
AQP5
aquaporin 5
chr1_-_111018798 0.842 KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr2_+_112372651 0.833 NM_006343
MERTK
c-mer proto-oncogene tyrosine kinase
chr18_-_70275441 0.825 NM_001044369
FAM69C
family with sequence similarity 69, member C
chr22_+_38183480 0.823 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr2_+_936534 0.822 NM_018968
SNTG2
syntrophin, gamma 2
chrX_-_51256166 0.819 NM_018159
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr1_+_4614528 0.818 AJAP1
adherens junctions associated protein 1
chrX_+_38305634 0.808 NM_004615
TSPAN7
tetraspanin 7
chr12_-_97812633 0.804 ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr5_-_146869811 0.800 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr1_+_2975590 0.800 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr6_+_107917965 0.796 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr7_-_27180398 0.793 NM_018951
HOXA10
homeobox A10
chrX_-_142550535 0.792 NM_173078
SLITRK4
SLIT and NTRK-like family, member 4
chr9_+_128416542 0.780 NM_001174146
NM_001174147
NM_002316
LMX1B


LIM homeobox transcription factor 1, beta


chr22_+_42138034 0.779 MPPED1
metallophosphoesterase domain containing 1
chr8_+_121892719 0.776


chr1_-_202921103 0.776 NM_006338
NM_201630
LRRN2

leucine rich repeat neuronal 2

chr7_+_113513828 0.775 FOXP2
forkhead box P2
chr15_-_38362078 0.773 NM_001190479
LOC100131244
hypothetical protein LOC100131244
chr1_+_22909916 0.770 NM_004442
NM_017449
EPHB2

EPH receptor B2

chr3_-_49882308 0.769 NM_024046
CAMKV
CaM kinase-like vesicle-associated
chr9_-_100598315 0.769 NM_173551
ANKS6
ankyrin repeat and sterile alpha motif domain containing 6

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.71 3.27e-28 GO:0007399 nervous system development
1.41 7.76e-27 GO:0007275 multicellular organismal development
1.38 6.03e-25 GO:0032502 developmental process
1.42 2.60e-21 GO:0048731 system development
1.38 8.11e-20 GO:0048856 anatomical structure development
1.49 1.89e-19 GO:0030154 cell differentiation
1.47 1.22e-18 GO:0048869 cellular developmental process
1.75 3.51e-18 GO:0048468 cell development
1.77 5.37e-18 GO:0048699 generation of neurons
1.56 6.46e-18 GO:0009653 anatomical structure morphogenesis
1.74 6.81e-18 GO:0022008 neurogenesis
1.82 4.57e-16 GO:0030182 neuron differentiation
1.87 1.34e-14 GO:0048666 neuron development
1.93 3.43e-14 GO:0031175 neuron projection development
1.89 6.57e-13 GO:0000904 cell morphogenesis involved in differentiation
1.94 6.90e-13 GO:0048812 neuron projection morphogenesis
1.18 8.75e-13 GO:0050794 regulation of cellular process
1.17 1.13e-12 GO:0050789 regulation of biological process
1.96 1.21e-12 GO:0007409 axonogenesis
1.86 1.98e-12 GO:0007417 central nervous system development
1.93 2.10e-12 GO:0048667 cell morphogenesis involved in neuron differentiation
1.76 2.93e-12 GO:0030030 cell projection organization
1.86 3.78e-12 GO:0048858 cell projection morphogenesis
1.16 5.32e-12 GO:0065007 biological regulation
1.84 8.85e-12 GO:0032990 cell part morphogenesis
1.76 2.65e-11 GO:0000902 cell morphogenesis
1.71 1.41e-10 GO:0032989 cellular component morphogenesis
1.25 3.88e-10 GO:0023052 signaling
1.10 5.49e-10 GO:0009987 cellular process
1.97 7.55e-10 GO:0007411 axon guidance
1.66 2.88e-08 GO:0009887 organ morphogenesis
1.37 5.98e-08 GO:0023051 regulation of signaling
1.34 1.11e-07 GO:0048513 organ development
1.58 1.63e-07 GO:0009790 embryo development
1.81 3.09e-07 GO:0007420 brain development
1.17 4.21e-07 GO:0032501 multicellular organismal process
1.59 5.32e-07 GO:0007167 enzyme linked receptor protein signaling pathway
1.50 5.64e-07 GO:0040011 locomotion
1.46 1.18e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.66 1.55e-06 GO:0019226 transmission of nerve impulse
1.66 1.55e-06 GO:0035637 multicellular organismal signaling
1.47 2.15e-06 GO:0050793 regulation of developmental process
1.48 3.66e-06 GO:0006351 transcription, DNA-dependent
1.81 4.00e-06 GO:0060284 regulation of cell development
1.69 4.33e-06 GO:0007268 synaptic transmission
1.68 5.83e-06 GO:0023057 negative regulation of signaling
1.54 6.52e-06 GO:0045595 regulation of cell differentiation
1.67 6.88e-06 GO:0010648 negative regulation of cell communication
1.65 7.35e-06 GO:0072358 cardiovascular system development
1.65 7.35e-06 GO:0072359 circulatory system development
1.21 1.12e-05 GO:0007165 signal transduction
1.79 1.70e-05 GO:0022603 regulation of anatomical structure morphogenesis
1.49 2.29e-05 GO:2000026 regulation of multicellular organismal development
1.27 2.41e-05 GO:0048523 negative regulation of cellular process
1.67 2.68e-05 GO:0009968 negative regulation of signal transduction
1.60 2.81e-05 GO:0048585 negative regulation of response to stimulus
1.58 6.36e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.58 7.33e-05 GO:0006935 chemotaxis
1.58 7.33e-05 GO:0042330 taxis
1.47 7.39e-05 GO:0007267 cell-cell signaling
1.25 8.10e-05 GO:0048519 negative regulation of biological process
1.29 9.99e-05 GO:0007166 cell surface receptor linked signaling pathway
2.18 1.10e-04 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.17 1.48e-04 GO:0022604 regulation of cell morphogenesis
1.23 1.62e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.23 1.66e-04 GO:0010468 regulation of gene expression
1.20 1.78e-04 GO:0060255 regulation of macromolecule metabolic process
1.32 3.24e-04 GO:0009966 regulation of signal transduction
1.33 3.61e-04 GO:0051239 regulation of multicellular organismal process
1.37 4.06e-04 GO:0010646 regulation of cell communication
1.23 4.33e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.67 4.74e-04 GO:0007389 pattern specification process
1.24 5.33e-04 GO:0051252 regulation of RNA metabolic process
1.37 6.13e-04 GO:0007154 cell communication
1.52 6.37e-04 GO:0051253 negative regulation of RNA metabolic process
1.74 6.48e-04 GO:0051960 regulation of nervous system development
1.38 6.85e-04 GO:0032879 regulation of localization
1.48 7.46e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.45 7.47e-04 GO:0009890 negative regulation of biosynthetic process
1.62 8.03e-04 GO:0009792 embryo development ending in birth or egg hatching
1.46 8.14e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.37 9.45e-04 GO:0032774 RNA biosynthetic process
1.52 9.86e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.48 1.02e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.66 1.03e-03 GO:0045597 positive regulation of cell differentiation
1.18 1.25e-03 GO:0080090 regulation of primary metabolic process
2.20 1.25e-03 GO:0010720 positive regulation of cell development
1.21 1.27e-03 GO:0031326 regulation of cellular biosynthetic process
1.21 1.38e-03 GO:0009889 regulation of biosynthetic process
1.61 1.62e-03 GO:0043009 chordate embryonic development
1.77 1.74e-03 GO:0007507 heart development
1.45 1.80e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.21 2.16e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.16 2.19e-03 GO:0051716 cellular response to stimulus
1.46 2.28e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.20 2.39e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.74 2.97e-03 GO:0050767 regulation of neurogenesis
1.17 2.97e-03 GO:0031323 regulation of cellular metabolic process
1.57 3.62e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.67 3.68e-03 GO:0051270 regulation of cellular component movement
1.35 4.29e-03 GO:0009605 response to external stimulus
1.23 4.40e-03 GO:0006355 regulation of transcription, DNA-dependent
1.45 6.16e-03 GO:0010629 negative regulation of gene expression
1.22 6.19e-03 GO:0042221 response to chemical stimulus
1.53 6.21e-03 GO:0032583 regulation of gene-specific transcription
1.19 6.70e-03 GO:0048518 positive regulation of biological process
1.53 8.96e-03 GO:0040008 regulation of growth
1.24 1.00e-02 GO:0006464 protein modification process
1.37 1.14e-02 GO:0051128 regulation of cellular component organization
1.33 1.19e-02 GO:0006793 phosphorus metabolic process
1.33 1.19e-02 GO:0006796 phosphate metabolic process
1.20 1.21e-02 GO:0048522 positive regulation of cellular process
1.64 1.24e-02 GO:0040012 regulation of locomotion
1.86 1.31e-02 GO:0006813 potassium ion transport
1.48 1.38e-02 GO:0030001 metal ion transport
1.68 1.96e-02 GO:0001558 regulation of cell growth
1.69 2.03e-02 GO:0048568 embryonic organ development
1.49 2.17e-02 GO:0051094 positive regulation of developmental process
1.63 2.26e-02 GO:0035295 tube development
1.35 2.37e-02 GO:0016310 phosphorylation
1.68 2.85e-02 GO:0003002 regionalization
1.22 2.94e-02 GO:0043412 macromolecule modification
1.14 3.00e-02 GO:0019222 regulation of metabolic process
4.93 3.41e-02 GO:0050919 negative chemotaxis
1.53 3.50e-02 GO:0048598 embryonic morphogenesis
1.53 3.71e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.37 3.75e-02 GO:0006468 protein phosphorylation
1.15 3.86e-02 GO:0051179 localization
2.25 4.13e-02 GO:0050770 regulation of axonogenesis
2.04 4.52e-02 GO:0003007 heart morphogenesis
1.59 4.57e-02 GO:0001944 vasculature development
3.82 4.70e-02 GO:0035412 regulation of catenin import into nucleus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.71 3.97e-07 GO:0045202 synapse
1.27 2.86e-06 GO:0044459 plasma membrane part
1.62 3.13e-05 GO:0043005 neuron projection
1.70 7.43e-05 GO:0044456 synapse part
1.48 8.32e-05 GO:0030054 cell junction
1.09 2.69e-04 GO:0043227 membrane-bounded organelle
1.08 4.34e-04 GO:0043231 intracellular membrane-bounded organelle
1.06 4.72e-04 GO:0044424 intracellular part
1.67 1.65e-03 GO:0005667 transcription factor complex
1.35 2.06e-03 GO:0042995 cell projection
1.38 2.72e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.37 3.74e-03 GO:0031988 membrane-bounded vesicle
1.11 4.00e-03 GO:0005634 nucleus
1.07 7.66e-03 GO:0043226 organelle
1.85 8.32e-03 GO:0034703 cation channel complex
1.05 8.35e-03 GO:0005622 intracellular
1.07 9.36e-03 GO:0043229 intracellular organelle
1.33 9.58e-03 GO:0031982 vesicle
1.33 1.43e-02 GO:0031410 cytoplasmic vesicle
2.04 1.57e-02 GO:0008076 voltage-gated potassium channel complex
2.04 1.57e-02 GO:0034705 potassium channel complex
1.08 1.66e-02 GO:0005737 cytoplasm
2.00 3.25e-02 GO:0008021 synaptic vesicle
2.04 4.70e-02 GO:0033267 axon part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.78 1.31e-15 GO:0043565 sequence-specific DNA binding
1.56 3.24e-12 GO:0030528 transcription regulator activity
1.55 1.99e-11 GO:0001071 nucleic acid binding transcription factor activity
1.55 1.99e-11 GO:0003700 sequence-specific DNA binding transcription factor activity
1.08 7.85e-08 GO:0005488 binding
1.13 1.88e-07 GO:0005515 protein binding
2.54 1.04e-05 GO:0019199 transmembrane receptor protein kinase activity
2.73 1.84e-05 GO:0004714 transmembrane receptor protein tyrosine kinase activity
1.59 5.72e-05 GO:0019904 protein domain specific binding
1.86 1.78e-04 GO:0010843 promoter binding
1.84 1.78e-04 GO:0000975 regulatory region DNA binding
1.84 1.78e-04 GO:0001067 regulatory region nucleic acid binding
1.84 1.78e-04 GO:0044212 transcription regulatory region DNA binding
1.70 4.18e-04 GO:0005261 cation channel activity
1.46 8.36e-04 GO:0008324 cation transmembrane transporter activity
4.99 1.81e-03 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity
1.42 2.86e-03 GO:0004672 protein kinase activity
1.59 4.23e-03 GO:0016564 transcription repressor activity
1.88 5.29e-03 GO:0022843 voltage-gated cation channel activity
1.57 9.09e-03 GO:0022836 gated channel activity
1.34 1.46e-02 GO:0016301 kinase activity
1.35 1.53e-02 GO:0015075 ion transmembrane transporter activity
1.54 1.69e-02 GO:0016563 transcription activator activity
2.24 1.82e-02 GO:0030165 PDZ domain binding
1.35 2.32e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.69 2.57e-02 GO:0005244 voltage-gated ion channel activity
1.69 2.57e-02 GO:0022832 voltage-gated channel activity
1.47 2.61e-02 GO:0005216 ion channel activity
1.18 2.69e-02 GO:0003677 DNA binding
3.59 2.95e-02 GO:0005003 ephrin receptor activity
1.46 3.07e-02 GO:0022838 substrate-specific channel activity
1.54 3.57e-02 GO:0008134 transcription factor binding
2.09 4.11e-02 GO:0005262 calcium channel activity
1.45 4.21e-02 GO:0015267 channel activity
1.80 4.37e-02 GO:0004713 protein tyrosine kinase activity
1.44 4.70e-02 GO:0022803 passive transmembrane transporter activity