Motif ID: ATF5_CREB3.p2

Z-value: 3.861


Transcription factors associated with ATF5_CREB3.p2:

Gene SymbolEntrez IDGene Name
ATF5 22809 activating transcription factor 5
CREB3 10488 cAMP responsive element binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF5chr19_+_55123770-0.811.5e-04Click!
CREB3chr9_+_357224900.656.4e-03Click!


Activity profile for motif ATF5_CREB3.p2.

activity profile for motif ATF5_CREB3.p2


Sorted Z-values histogram for motif ATF5_CREB3.p2

Sorted Z-values for motif ATF5_CREB3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF5_CREB3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_187884721 8.829


chr3_+_189354167 7.171 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr19_+_50663089 7.078 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr20_+_19863716 6.812 RIN2
Ras and Rab interactor 2
chr1_-_16355013 6.578 NM_004431
EPHA2
EPH receptor A2
chr20_+_32610161 6.401 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr16_-_78192111 6.386 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr2_-_156897286 6.333 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr2_-_216009015 6.000 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr14_+_74815233 5.908 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr10_+_102782151 5.709 SFXN3
sideroflexin 3
chr12_-_121946581 5.132 VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr11_+_12652427 4.962 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr14_+_100362236 4.926 MEG3
maternally expressed 3 (non-protein coding)
chr18_+_44319365 4.903 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr14_+_100362204 4.894 MEG3
maternally expressed 3 (non-protein coding)
chr7_+_28415495 4.889 LOC401317
hypothetical LOC401317
chr9_+_101623957 4.730 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr20_+_19903778 4.516 RIN2
Ras and Rab interactor 2
chr5_-_57791544 4.428 NM_006622
PLK2
polo-like kinase 2
chr4_+_75529716 4.396 NM_001657
AREG
amphiregulin
chr21_+_32706615 4.394 NM_058187
C21orf63
chromosome 21 open reading frame 63
chr1_-_212791467 4.388 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr4_+_145786622 4.386 NM_022475
HHIP
hedgehog interacting protein
chr5_-_59100194 4.370 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_212791597 4.353 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr8_+_94998258 4.350 NM_018444
NM_001161780
NM_001161779
NM_001161781
PDP1



pyruvate dehyrogenase phosphatase catalytic subunit 1



chr12_-_121946561 4.349


chr2_-_216008689 4.271 FN1
fibronectin 1
chr12_-_121946635 4.268 NM_024667
VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr4_+_85723080 4.203 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr5_-_1935764 4.119 NM_016358
IRX4
iroquois homeobox 4
chrX_-_83644054 4.095 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr1_-_184916044 4.066 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr4_-_186693574 4.051 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr10_-_90957028 4.025 NM_003956
CH25H
cholesterol 25-hydroxylase
chr4_+_75699652 4.012 NM_001657
AREG
amphiregulin
chr8_-_95343696 3.997 GEM
GTP binding protein overexpressed in skeletal muscle
chr3_-_189354510 3.995 LOC339929
hypothetical LOC339929
chr6_-_128883125 3.990 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr1_-_208046011 3.789 NM_006147
IRF6
interferon regulatory factor 6
chr20_-_55718351 3.773 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr5_-_58607673 3.753 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chrX_-_106846684 3.752 TSC22D3
TSC22 domain family, member 3
chr19_+_50041424 3.699 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr12_+_12935619 3.657 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr3_+_159771646 3.651 NM_001130156
NM_001130157
NM_001195432
NM_001195433
NM_001195434
NM_022443
MLF1





myeloid leukemia factor 1





chr19_+_50041400 3.648 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr8_-_95343716 3.637 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr3_-_71196696 3.636 FOXP1
forkhead box P1
chr2_+_28469172 3.599 FOSL2
FOS-like antigen 2
chr12_+_12935759 3.562 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr1_+_156229934 3.490 KIRREL
kin of IRRE like (Drosophila)
chr6_-_38715901 3.486 NM_001099272
NM_052893
BTBD9

BTB (POZ) domain containing 9

chrX_+_100692071 3.474 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr5_-_59100091 3.415 PDE4D
phosphodiesterase 4D, cAMP-specific
chr9_+_111582317 3.397 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr12_+_12935222 3.391 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr6_-_38715613 3.390 BTBD9
BTB (POZ) domain containing 9
chr19_+_50041387 3.353 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr1_+_154297588 3.346 NM_020387
RAB25
RAB25, member RAS oncogene family
chrX_-_106846924 3.289 NM_004089
TSC22D3
TSC22 domain family, member 3
chr2_-_222145240 3.285 NM_004438
EPHA4
EPH receptor A4
chr5_+_52812165 3.283 FST
follistatin
chr7_-_27120015 3.283 HOXA3
homeobox A3
chr5_+_52812236 3.242 NM_006350
NM_013409
FST

follistatin

chr5_+_159276317 3.173 NM_000679
ADRA1B
adrenergic, alpha-1B-, receptor
chr5_+_148186348 3.144 NM_000024
ADRB2
adrenergic, beta-2-, receptor, surface
chr1_+_156229686 3.141 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr6_-_38715567 3.132 BTBD9
BTB (POZ) domain containing 9
chr12_-_123568781 3.119


chr11_+_94141151 3.104 NM_130847
AMOTL1
angiomotin like 1
chr5_+_60663842 3.065 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr10_+_102782156 3.001 SFXN3
sideroflexin 3
chr1_-_95165089 2.985 NM_001839
CNN3
calponin 3, acidic
chr9_-_14303509 2.959 NFIB
nuclear factor I/B
chr1_+_85819004 2.950 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr4_-_24523605 2.926 NM_001130726
CCDC149
coiled-coil domain containing 149
chr12_-_113606322 2.926 NM_005996
NM_016569
TBX3

T-box 3

chr14_+_67156405 2.878 ARG2
arginase, type II
chr16_+_22733307 2.870 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr2_+_28469275 2.870 NM_005253
FOSL2
FOS-like antigen 2
chr2_+_28469199 2.850 FOSL2
FOS-like antigen 2
chr3_-_192063158 2.816 NM_001146686
GEMC1
geminin coiled-coil domain-containing protein 1
chr6_+_30402986 2.805 NM_172016
TRIM39
tripartite motif containing 39
chr6_+_30402599 2.798 NM_021253
TRIM39
tripartite motif containing 39
chr3_+_185538998 2.782 FAM131A
family with sequence similarity 131, member A
chr4_+_152549776 2.762 NM_001109977
FAM160A1
family with sequence similarity 160, member A1
chr1_-_95165037 2.746 CNN3
calponin 3, acidic
chr13_-_20533703 2.729 NM_014572
LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr20_+_51023159 2.703 TSHZ2
teashirt zinc finger homeobox 2
chr11_-_35503720 2.693 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr18_+_7557313 2.687 NM_001105244
NM_002845
PTPRM

protein tyrosine phosphatase, receptor type, M

chr20_+_10147455 2.676 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr14_+_67156323 2.672 NM_001172
ARG2
arginase, type II
chr14_+_67156386 2.657 ARG2
arginase, type II
chr9_-_109291866 2.635 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr3_-_64186151 2.617 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr20_+_55718718 2.603


chr2_-_202354139 2.560 NM_001135745
NM_020919
ALS2

amyotrophic lateral sclerosis 2 (juvenile)

chr5_-_37875538 2.538 NM_000514
GDNF
glial cell derived neurotrophic factor
chr17_+_8279860 2.533 NM_001025579
NM_030808
NDEL1

nudE nuclear distribution gene E homolog (A. nidulans)-like 1

chr1_-_20682541 2.526


chrX_-_133984157 2.521 NM_001078173
FAM127C
family with sequence similarity 127, member C
chr20_+_55718619 2.478


chr1_+_191044791 2.472 NM_002923
RGS2
regulator of G-protein signaling 2, 24kDa
chr2_-_216944911 2.453 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr11_+_69165018 2.435 NM_053056
CCND1
cyclin D1
chr8_-_18915443 2.433 NM_015310
PSD3
pleckstrin and Sec7 domain containing 3
chr12_-_62902279 2.432 NM_152440
C12orf66
chromosome 12 open reading frame 66
chr12_-_14847582 2.423 WBP11
WW domain binding protein 11
chr10_-_31360778 2.408 NM_001143766
NM_001143767
NM_001143768
NM_001143770
NM_001143771
NM_182755
ZNF438





zinc finger protein 438





chr8_+_37672427 2.402 NM_025069
ZNF703
zinc finger protein 703
chr4_+_158216631 2.379 NM_000824
NM_001166061
NM_001166060
GLRB


glycine receptor, beta


chr6_-_91063181 2.365 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr14_-_22458199 2.359 RBM23
RNA binding motif protein 23
chr21_-_34820916 2.355 NM_203418
RCAN1
regulator of calcineurin 1
chr14_+_75521806 2.341 NM_001102564
NM_052873
C14orf179

chromosome 14 open reading frame 179

chr7_+_30140868 2.334 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr12_-_14847634 2.314 NM_016312
WBP11
WW domain binding protein 11
chr6_+_1555679 2.305 NM_001453
FOXC1
forkhead box C1
chr1_+_19843261 2.303 NM_005380
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr13_-_20533629 2.298 LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr11_+_101291134 2.287 KIAA1377
KIAA1377
chr20_-_49612745 2.272 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr12_-_14847675 2.268 WBP11
WW domain binding protein 11
chr16_+_85169615 2.254 NM_005250
FOXL1
forkhead box L1
chr14_-_22458134 2.250 RBM23
RNA binding motif protein 23
chr15_-_61461127 2.247 NM_001218
NM_206925
CA12

carbonic anhydrase XII

chr4_-_88032570 2.234 NM_144645
C4orf36
chromosome 4 open reading frame 36
chr1_+_85300580 2.232 NM_145172
WDR63
WD repeat domain 63
chr21_-_42060266 2.215 NM_020639
RIPK4
receptor-interacting serine-threonine kinase 4
chr9_-_98421894 2.195 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr11_+_69165159 2.194 CCND1
cyclin D1
chrX_-_51256166 2.183 NM_018159
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr11_+_69165065 2.160 CCND1
cyclin D1
chr18_+_45342398 2.159 NM_006033
LIPG
lipase, endothelial
chr22_+_36927884 2.159 NM_001161572
NM_001161574
NM_012323
MAFF


v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)


chr17_+_38831874 2.159 NM_001661
ARL4D
ADP-ribosylation factor-like 4D
chr3_-_53900888 2.158 NM_021237
SELK
selenoprotein K
chr2_-_73193566 2.152 RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr11_+_69165119 2.144 CCND1
cyclin D1
chr5_+_102229612 2.140 PAM
peptidylglycine alpha-amidating monooxygenase
chr21_-_43671355 2.125 NM_173354
SIK1
salt-inducible kinase 1
chr12_+_4300607 2.120 NM_020375
C12orf5
chromosome 12 open reading frame 5
chr6_+_148705817 2.118 SASH1
SAM and SH3 domain containing 1
chr6_+_139497933 2.106 NM_016217
HECA
headcase homolog (Drosophila)
chr6_+_116798791 2.100 NM_013352
DSE
dermatan sulfate epimerase
chr21_-_42060334 2.094 RIPK4
receptor-interacting serine-threonine kinase 4
chrX_+_102518064 2.092 NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr1_+_216585298 2.090 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr7_+_288051 2.085 NM_020223
FAM20C
family with sequence similarity 20, member C
chr7_-_121571472 2.082 NM_005763
AASS
aminoadipate-semialdehyde synthase
chr1_-_20685314 2.078 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr20_-_10602429 2.073 NM_000214
JAG1
jagged 1
chr8_+_128875902 2.065 PVT1
Pvt1 oncogene (non-protein coding)
chr14_-_52487022 2.063 FERMT2
fermitin family member 2
chr7_+_27102508 2.059


chr8_-_48813236 2.049 CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr5_+_102229425 2.046 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr7_-_143523582 2.043 NM_001003702
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr3_+_8518539 2.038 LMCD1
LIM and cysteine-rich domains 1
chr8_-_48813256 2.036 NM_005195
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr3_+_113060716 2.027 NM_001134438
NM_145753
PHLDB2

pleckstrin homology-like domain, family B, member 2

chr16_-_4528380 2.007 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr8_+_134272463 2.004 NM_003882
NM_080838
WISP1

WNT1 inducible signaling pathway protein 1

chr3_-_87122958 1.995 VGLL3
vestigial like 3 (Drosophila)
chr22_+_36928011 1.985 MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr3_+_23962518 1.979 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr12_+_14847772 1.973 NM_175874
LOC100125871
C12orf60
hypothetical protein LOC100125871
chromosome 12 open reading frame 60
chrX_-_51256035 1.972 NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr14_-_22458220 1.970 NM_001077351
NM_001077352
NM_018107
RBM23


RNA binding motif protein 23


chr14_+_50096603 1.967 ATL1
atlastin GTPase 1
chrX_+_102498035 1.953 NM_001006612
NM_001006613
NM_001006614
NM_016303
WBP5



WW domain binding protein 5



chr17_+_37098668 1.952 EIF1
eukaryotic translation initiation factor 1
chr7_-_27158726 1.951


chr7_-_27108826 1.951 NM_006735
HOXA2
homeobox A2
chr10_+_134060681 1.941 NM_001098637
NM_138499
PWWP2B

PWWP domain containing 2B

chr12_+_55201854 1.940 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr5_-_50714836 1.936 LOC642366
hypothetical LOC642366
chr6_-_161614962 1.931 NM_020133
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr12_-_113330574 1.929 NM_000192
NM_080717
TBX5

T-box 5

chr11_+_110916629 1.919 LAYN
layilin
chr7_+_27102197 1.919


chr3_-_8518327 1.913 LOC100288428
hypothetical LOC100288428
chr3_+_62279707 1.899 C3orf14
chromosome 3 open reading frame 14
chr10_+_112247614 1.897 NM_004419
DUSP5
dual specificity phosphatase 5
chr4_-_140696740 1.895 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr19_+_50041232 1.888 NM_001042724
NM_002856
PVRL2

poliovirus receptor-related 2 (herpesvirus entry mediator B)

chr9_-_89779413 1.885 NM_001039803
NM_001170639
NM_001170640
NM_012119
NM_178432
CDK20




cyclin-dependent kinase 20




chrX_+_110226030 1.877 NM_002578
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr20_+_29656744 1.870 NM_002165
NM_181353
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr16_+_53522611 1.857 NM_005853
IRX5
iroquois homeobox 5
chr2_+_30223304 1.853 YPEL5
yippee-like 5 (Drosophila)
chr3_+_101462375 1.851 NM_018309
TBC1D23
TBC1 domain family, member 23
chr14_+_50096492 1.848 NM_015915
NM_181598
ATL1

atlastin GTPase 1

chrX_+_133993984 1.837 NM_001078171
FAM127A
family with sequence similarity 127, member A
chr1_-_8008934 1.836 ERRFI1
ERBB receptor feedback inhibitor 1
chr2_+_30223253 1.836 NM_001127399
NM_001127400
NM_001127401
NM_016061
YPEL5



yippee-like 5 (Drosophila)



chr14_-_44500871 1.834 NM_017658
KLHL28
kelch-like 28 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.36 2.94e-15 GO:0044260 cellular macromolecule metabolic process
1.31 4.93e-13 GO:0043170 macromolecule metabolic process
1.25 3.08e-11 GO:0044237 cellular metabolic process
1.12 9.77e-09 GO:0009987 cellular process
1.21 3.04e-08 GO:0044238 primary metabolic process
1.46 1.86e-07 GO:0010467 gene expression
1.30 3.74e-07 GO:0031323 regulation of cellular metabolic process
1.37 7.16e-07 GO:0044267 cellular protein metabolic process
1.18 1.38e-06 GO:0008152 metabolic process
1.54 1.43e-06 GO:0051641 cellular localization
1.45 3.26e-06 GO:0009059 macromolecule biosynthetic process
1.30 3.78e-06 GO:0060255 regulation of macromolecule metabolic process
1.36 4.83e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.67 7.08e-06 GO:0046907 intracellular transport
1.44 7.26e-06 GO:0034645 cellular macromolecule biosynthetic process
1.17 9.21e-06 GO:0050794 regulation of cellular process
1.28 9.45e-06 GO:0080090 regulation of primary metabolic process
1.34 1.19e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.55 1.23e-05 GO:0051649 establishment of localization in cell
1.37 1.30e-05 GO:0090304 nucleic acid metabolic process
1.33 1.68e-05 GO:0031326 regulation of cellular biosynthetic process
1.42 1.81e-05 GO:0016070 RNA metabolic process
1.32 1.90e-05 GO:0009889 regulation of biosynthetic process
1.34 2.70e-05 GO:0048522 positive regulation of cellular process
1.25 3.26e-05 GO:0019222 regulation of metabolic process
1.54 4.28e-05 GO:0008104 protein localization
1.32 6.65e-05 GO:0010468 regulation of gene expression
1.30 8.61e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59 9.60e-05 GO:0045184 establishment of protein localization
1.58 1.12e-04 GO:0006351 transcription, DNA-dependent
1.28 1.35e-04 GO:0034641 cellular nitrogen compound metabolic process
1.58 1.79e-04 GO:0015031 protein transport
1.45 1.93e-04 GO:0033036 macromolecule localization
1.15 1.94e-04 GO:0050789 regulation of biological process
1.26 2.56e-04 GO:0006807 nitrogen compound metabolic process
1.29 3.16e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.28 3.31e-04 GO:0019538 protein metabolic process
1.29 4.33e-04 GO:0048518 positive regulation of biological process
1.29 4.70e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31 1.11e-03 GO:0051252 regulation of RNA metabolic process
1.34 1.82e-03 GO:0006464 protein modification process
1.49 2.23e-03 GO:0032774 RNA biosynthetic process
1.29 2.81e-03 GO:0044249 cellular biosynthetic process
1.31 2.89e-03 GO:0006355 regulation of transcription, DNA-dependent
1.13 3.72e-03 GO:0065007 biological regulation
1.27 7.09e-03 GO:0009058 biosynthetic process
1.91 7.27e-03 GO:0010608 posttranscriptional regulation of gene expression
1.46 8.18e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.31 8.27e-03 GO:0043412 macromolecule modification
1.37 1.75e-02 GO:0035556 intracellular signal transduction
2.77 1.94e-02 GO:0002755 MyD88-dependent toll-like receptor signaling pathway
1.24 2.22e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.62 2.33e-02 GO:0034613 cellular protein localization
2.80 2.63e-02 GO:0034130 toll-like receptor 1 signaling pathway
2.80 2.63e-02 GO:0034134 toll-like receptor 2 signaling pathway
1.42 2.94e-02 GO:0006793 phosphorus metabolic process
1.42 2.94e-02 GO:0006796 phosphate metabolic process
1.61 2.99e-02 GO:0070727 cellular macromolecule localization
1.21 3.07e-02 GO:0071840 cellular component organization or biogenesis
1.21 3.29e-02 GO:0016043 cellular component organization
1.24 3.59e-02 GO:0071842 cellular component organization at cellular level
1.38 4.10e-02 GO:0031325 positive regulation of cellular metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.16 2.07e-20 GO:0005622 intracellular
1.16 3.45e-20 GO:0044424 intracellular part
1.21 2.55e-17 GO:0043231 intracellular membrane-bounded organelle
1.21 3.98e-17 GO:0043227 membrane-bounded organelle
1.18 1.35e-15 GO:0043229 intracellular organelle
1.17 2.84e-15 GO:0043226 organelle
1.19 2.73e-12 GO:0005737 cytoplasm
1.26 1.14e-11 GO:0005634 nucleus
1.25 4.54e-11 GO:0044422 organelle part
1.25 1.10e-10 GO:0044446 intracellular organelle part
1.40 6.32e-08 GO:0044428 nuclear part
1.40 2.07e-06 GO:0031981 nuclear lumen
1.17 8.25e-05 GO:0044444 cytoplasmic part
1.32 8.45e-05 GO:0070013 intracellular organelle lumen
1.31 8.96e-05 GO:0043233 organelle lumen
1.30 1.43e-04 GO:0031974 membrane-enclosed lumen
1.56 6.35e-04 GO:0015630 microtubule cytoskeleton
1.39 6.55e-04 GO:0005654 nucleoplasm
1.24 1.18e-03 GO:0043234 protein complex
1.45 1.38e-03 GO:0005794 Golgi apparatus
1.49 5.20e-03 GO:0044451 nucleoplasm part
1.26 8.68e-03 GO:0031090 organelle membrane
1.25 2.38e-02 GO:0005829 cytosol
1.50 2.62e-02 GO:0044431 Golgi apparatus part
1.65 3.83e-02 GO:0005815 microtubule organizing center
1.18 3.98e-02 GO:0032991 macromolecular complex
1.43 4.22e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
2.11 4.97e-02 GO:0016607 nuclear speck

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.24 1.55e-15 GO:0005515 protein binding
1.12 4.17e-12 GO:0005488 binding
1.61 2.37e-07 GO:0001071 nucleic acid binding transcription factor activity
1.61 2.37e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.63 6.25e-05 GO:0043565 sequence-specific DNA binding
1.24 2.75e-04 GO:0003676 nucleic acid binding
1.30 2.77e-04 GO:0000166 nucleotide binding
1.47 3.60e-04 GO:0030528 transcription regulator activity
1.52 6.96e-04 GO:0003723 RNA binding
1.32 1.33e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.94 1.57e-03 GO:0003702 RNA polymerase II transcription factor activity
1.31 1.79e-03 GO:0017076 purine nucleotide binding
1.31 2.35e-03 GO:0032553 ribonucleotide binding
1.31 2.35e-03 GO:0032555 purine ribonucleotide binding
2.02 2.86e-02 GO:0004721 phosphoprotein phosphatase activity