Motif ID: EBF1.p2

Z-value: 2.453


Transcription factors associated with EBF1.p2:

Gene SymbolEntrez IDGene Name
EBF1 1879 early B-cell factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EBF1chr5_-_1584592760.224.1e-01Click!


Activity profile for motif EBF1.p2.

activity profile for motif EBF1.p2


Sorted Z-values histogram for motif EBF1.p2

Sorted Z-values for motif EBF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EBF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_-_35875890 4.122 NM_000878
IL2RB
interleukin 2 receptor, beta
chr15_-_77024375 3.568 CTSH
cathepsin H
chr9_+_139292094 3.537 NM_017723
C9orf167
chromosome 9 open reading frame 167
chr15_-_77024408 2.484 NM_004390
CTSH
cathepsin H
chr16_+_28850760 2.340 NM_001178098
NM_001770
CD19

CD19 molecule

chr10_-_135021502 2.299 NM_001098483
NM_198472
C10orf125

chromosome 10 open reading frame 125

chr17_+_53769659 2.157 LOC100506779
hypothetical LOC100506779
chr16_+_28413421 2.142 NM_018690
APOBR
apolipoprotein B receptor
chr17_-_35975227 2.124 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr16_+_66236559 2.056 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr19_+_55627971 2.056 NM_004533
MYBPC2
myosin binding protein C, fast type
chr7_+_128365226 2.056 NM_001098629
NM_001098630
IRF5

interferon regulatory factor 5

chr6_-_32742265 2.026 NM_002123
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr17_+_73676219 1.984 NM_004710
SYNGR2
synaptogyrin 2
chr19_+_47073029 1.958 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr6_-_167195647 1.950 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr17_-_50854054 1.927 NM_012329
MMD
monocyte to macrophage differentiation-associated
chr1_-_200397300 1.908 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr21_-_36836767 1.869 NM_001146078
CLDN14
claudin 14
chr22_+_35586950 1.787 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr7_+_101860958 1.784 NM_001126340
NM_032831
ORAI2

ORAI calcium release-activated calcium modulator 2

chr17_+_73638430 1.771 NM_152468
TMC8
transmembrane channel-like 8
chr9_+_4480193 1.716 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr17_+_71095733 1.696 MYO15B
myosin XVB pseudogene
chr17_+_44642587 1.669 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr19_+_17723285 1.659 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr7_-_149960218 1.645 GIMAP6
GTPase, IMAP family member 6
chr17_-_44642934 1.630 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr14_-_104602784 1.630 NM_013345
GPR132
G protein-coupled receptor 132
chr18_-_6404900 1.606 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr17_+_44643067 1.588 ABI3
ABI family, member 3
chr7_+_128365482 1.586 NM_032643
IRF5
interferon regulatory factor 5
chr10_-_21825879 1.580 C10orf114
chromosome 10 open reading frame 114
chr14_+_60858151 1.577 NM_006255
PRKCH
protein kinase C, eta
chr16_+_658081 1.570 NM_138769
RHOT2
ras homolog gene family, member T2
chrX_-_39921525 1.562 NM_001123383
NM_001123384
BCOR

BCL6 corepressor

chr4_+_42094612 1.549 NM_001080505
SHISA3
shisa homolog 3 (Xenopus laevis)
chr19_-_1993022 1.549 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr19_+_10242763 1.534 ICAM1
intercellular adhesion molecule 1
chr6_-_167195987 1.491 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr7_+_139175420 1.468 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr1_+_32489426 1.467 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr17_-_53764867 1.462


chr19_+_4180494 1.458 NM_005755
EBI3
Epstein-Barr virus induced 3
chr16_+_658158 1.436 RHOT2
ras homolog gene family, member T2
chr15_-_36644122 1.420 NM_001128602
NM_005739
RASGRP1

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

chr7_+_101861007 1.417 ORAI2
ORAI calcium release-activated calcium modulator 2
chr11_-_57038891 1.405 NM_001198810
SLC43A1
solute carrier family 43, member 1
chr7_-_960534 1.393 ADAP1
ArfGAP with dual PH domains 1
chr4_-_6253152 1.386 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr19_+_18312365 1.381 NM_017712
FKBP8
PGPEP1
FK506 binding protein 8, 38kDa
pyroglutamyl-peptidase I
chr17_-_35337288 1.369 NM_139280
ORMDL3
ORM1-like 3 (S. cerevisiae)
chr1_-_200396354 1.343 NM_002832
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr14_+_102659464 1.317 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr11_+_817584 1.309 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr5_-_132194488 1.304 NM_001172700
SHROOM1
shroom family member 1
chr1_+_110000247 1.300 GSTM4
glutathione S-transferase mu 4
chr19_-_1992862 1.275 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr5_-_149772563 1.270 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr11_-_66961709 1.269 NM_005608
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr1_+_110000396 1.266 GSTM2
GSTM4
glutathione S-transferase mu 2 (muscle)
glutathione S-transferase mu 4
chr19_+_10242516 1.263 NM_000201
ICAM1
intercellular adhesion molecule 1
chr17_-_59363352 1.253 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr10_+_70257299 1.252 NM_001130159
NM_001130160
NM_001130161
NM_152709
STOX1



storkhead box 1



chr22_+_23153529 1.248 NM_000675
ADORA2A
adenosine A2a receptor
chr2_+_96355661 1.238 NM_178495
NM_001163524
ITPRIPL1

inositol 1,4,5-triphosphate receptor interacting protein-like 1

chr10_+_71908535 1.237 NM_014431
KIAA1274
KIAA1274
chr4_-_40327396 1.234 RBM47
RNA binding motif protein 47
chr17_-_39652449 1.213 NM_001076684
UBTF
upstream binding transcription factor, RNA polymerase I
chr7_+_26298018 1.200 NM_013322
SNX10
sorting nexin 10
chr1_+_110000220 1.194 NM_000850
NM_147148
GSTM4

glutathione S-transferase mu 4

chr2_-_242449662 1.180 NM_005018
PDCD1
programmed cell death 1
chr17_-_16816113 1.167 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr17_-_40843530 1.166 ARHGAP27
Rho GTPase activating protein 27
chr17_-_43862480 1.154 NM_001075099
NM_003726
SKAP1

src kinase associated phosphoprotein 1

chr17_-_39652391 1.140 UBTF
upstream binding transcription factor, RNA polymerase I
chr22_-_49042065 1.136 NM_002969
MAPK12
mitogen-activated protein kinase 12
chr19_+_7608020 1.135 STXBP2
syntaxin binding protein 2
chr10_+_114125003 1.134 NM_203380
ACSL5
acyl-CoA synthetase long-chain family member 5
chr3_+_123882355 1.130 NM_017554
PARP14
poly (ADP-ribose) polymerase family, member 14
chr14_-_23734598 1.118 NM_001014842
NM_006405
TM9SF1

transmembrane 9 superfamily member 1

chr1_+_205694237 1.113 NM_001006658
NM_001877
CR2

complement component (3d/Epstein Barr virus) receptor 2

chr6_-_119712596 1.099 NM_005907
MAN1A1
mannosidase, alpha, class 1A, member 1
chr10_+_11247467 1.099 CELF2
CUGBP, Elav-like family member 2
chr9_-_116190038 1.083 AKNA
AT-hook transcription factor
chr11_+_65164167 1.083 NM_153253
SIPA1
signal-induced proliferation-associated 1
chr20_-_43974092 1.078 NM_006227
NM_182676
PLTP

phospholipid transfer protein

chr17_+_75808685 1.075 NM_001166347
NM_001166348
NM_001166349
NM_173626
SLC26A11



solute carrier family 26, member 11



chr5_-_149772469 1.073 NM_001025159
NM_004355
NM_001025158
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr17_-_75808680 1.072 NM_000199
SGSH
N-sulfoglucosamine sulfohydrolase
chr3_-_13032130 1.065


chr8_-_70907957 1.057 NM_001146009
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr17_+_72958207 1.054 NM_001113496
SEPT9
septin 9
chr7_+_26298136 1.042 SNX10
sorting nexin 10
chr17_+_53761293 1.037 LOC100506779
hypothetical LOC100506779
chr7_-_960785 1.036 NM_006869
ADAP1
ArfGAP with dual PH domains 1
chr17_-_64834780 1.033 NM_172232
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr22_+_44925162 1.018 NM_001001928
NM_005036
PPARA

peroxisome proliferator-activated receptor alpha

chr9_-_135334003 0.996 NM_001145099
NM_017585
SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr9_-_19117494 0.981 NM_001122
PLIN2
perilipin 2
chr4_+_37569093 0.981 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr14_-_23734446 0.978 TM9SF1
transmembrane 9 superfamily member 1
chr19_+_44595589 0.976 NM_022835
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr12_-_123617962 0.966 NM_001077261
NM_006312
NCOR2

nuclear receptor corepressor 2

chr1_-_154727014 0.962 MEF2D
myocyte enhancer factor 2D
chr16_+_716936 0.960 NM_207112
NM_032304
HAGHL

hydroxyacylglutathione hydrolase-like

chr19_-_43608641 0.959 NM_001146202
NM_001146203
NM_001146204
NM_001146205
NM_001146206
NM_001146207
NM_170604
RASGRP4






RAS guanyl releasing protein 4






chr22_+_48971067 0.957 TRABD
TraB domain containing
chr19_+_60851207 0.957 CCDC106
coiled-coil domain containing 106
chr20_+_42644633 0.951 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr5_+_133478252 0.944 NM_003202
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr9_-_19117462 0.941 PLIN2
perilipin 2
chr11_+_61276576 0.939 NM_001127392
C11orf9
chromosome 11 open reading frame 9
chr7_-_86942910 0.936 NM_000443
NM_018849
NM_018850
ABCB4


ATP-binding cassette, sub-family B (MDR/TAP), member 4


chr5_-_100266769 0.928 NM_175052
NM_005668
ST8SIA4

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

chr14_-_106330781 0.906 IGHV5-78
immunoglobulin heavy variable 5-78 pseudogene
chr22_-_28992787 0.906 NM_020530
OSM
oncostatin M
chr2_-_96887353 0.904 NM_016466
ANKRD39
ankyrin repeat domain 39
chr10_+_26767288 0.899 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr14_-_23734433 0.896 TM9SF1
transmembrane 9 superfamily member 1
chr10_+_82158186 0.896 NM_032333
C10orf58
chromosome 10 open reading frame 58
chr11_-_63750138 0.896 NM_001033678
NM_001160389
NM_001160390
NM_001160392
NM_031472
TRPT1




tRNA phosphotransferase 1




chr8_-_70908130 0.894 NM_001146008
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr19_+_45811856 0.893 LTBP4
latent transforming growth factor beta binding protein 4
chr20_+_41576459 0.891 NM_015478
L3MBTL1
l(3)mbt-like 1 (Drosophila)
chr7_-_86526880 0.889 NM_001142749
KIAA1324L
KIAA1324-like
chr6_+_33151703 0.882 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr13_-_98757634 0.882 NM_004951
GPR183
G protein-coupled receptor 183
chr14_+_23633101 0.881 NM_001018073
NM_004563
PCK2

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

chr16_+_57091546 0.881 NDRG4
NDRG family member 4
chr16_+_1979959 0.879 NM_004209
SYNGR3
synaptogyrin 3
chr3_+_38154972 0.868 NM_001172566
NM_001172567
NM_001172568
NM_001172569
NM_002468
MYD88




myeloid differentiation primary response gene (88)




chr22_-_49315265 0.864 TYMP
thymidine phosphorylase
chr20_+_62181878 0.857 NM_000913
NM_182647
OPRL1

opiate receptor-like 1

chr12_-_50004102 0.857 BIN2
bridging integrator 2
chr8_+_22354276 0.854 PPP3CC
protein phosphatase 3, catalytic subunit, gamma isozyme
chr20_-_61809753 0.853 NM_001134758
NM_003224
ARFRP1

ADP-ribosylation factor related protein 1

chr11_+_73037382 0.853 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr20_+_275329 0.852 NM_024958
NRSN2
neurensin 2
chr8_-_30704984 0.852 NM_000637
NM_001195102
NM_001195103
NM_001195104
GSR



glutathione reductase



chr21_+_25856311 0.849 MIR155HG
MIR155 host gene (non-protein coding)
chr19_+_8180179 0.845 NM_024552
LASS4
LAG1 homolog, ceramide synthase 4
chr11_-_63749916 0.842 NM_001160393
TRPT1
tRNA phosphotransferase 1
chr2_+_96354754 0.834 NM_001008949
NM_001163523
ITPRIPL1

inositol 1,4,5-triphosphate receptor interacting protein-like 1

chrX_+_128741562 0.828 NM_018990
SASH3
SAM and SH3 domain containing 3
chr3_-_198180005 0.827 NM_025163
PIGZ
phosphatidylinositol glycan anchor biosynthesis, class Z
chr17_+_72958330 0.826 SEPT9
septin 9
chrX_-_48212683 0.825 SLC38A5
solute carrier family 38, member 5
chr3_-_50335113 0.825 NM_003773
NM_033158
HYAL2

hyaluronoglucosaminidase 2

chr9_+_131123115 0.821 NM_001012715
C9orf106
chromosome 9 open reading frame 106
chr20_+_30814048 0.820 DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr20_-_45410033 0.819 ZMYND8
zinc finger, MYND-type containing 8
chr16_+_65840275 0.818 NM_004594
SLC9A5
solute carrier family 9 (sodium/hydrogen exchanger), member 5
chrX_-_154146930 0.817 NM_171998
RAB39B
RAB39B, member RAS oncogene family
chr1_+_179719338 0.814 NM_000721
CACNA1E
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr19_-_12373022 0.810 NM_001080821
ZNF799
zinc finger protein 799
chr15_-_38188333 0.807 NM_001003940
BMF
Bcl2 modifying factor
chr4_+_2764609 0.806 SH3BP2
SH3-domain binding protein 2
chr8_+_145553016 0.805 NM_024531
GPR172A
G protein-coupled receptor 172A
chr6_+_34541827 0.803 NM_020804
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chrX_+_128741578 0.803 SASH3
SAM and SH3 domain containing 3
chr17_-_8034071 0.801 C17orf59
chromosome 17 open reading frame 59
chr2_+_43919606 0.800 NM_022437
ABCG8
ATP-binding cassette, sub-family G (WHITE), member 8
chr16_-_30477006 0.796 NM_001172679
NM_033410
ZNF764

zinc finger protein 764

chr16_+_66236512 0.796 NM_001013838
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chrX_-_153360411 0.795 LAGE3
L antigen family, member 3
chr20_+_41729161 0.794 MYBL2
v-myb myeloblastosis viral oncogene homolog (avian)-like 2
chr7_-_960897 0.790 ADAP1
ArfGAP with dual PH domains 1
chr4_+_2764510 0.788 NM_001122681
SH3BP2
SH3-domain binding protein 2
chr22_+_30072739 0.787 FLJ20464
hypothetical protein FLJ20464
chr19_-_14121728 0.784 LPHN1
latrophilin 1
chr21_-_45786709 0.773 NM_194255
SLC19A1
solute carrier family 19 (folate transporter), member 1
chr14_+_74964672 0.772 NM_001135048
NM_130469
JDP2

Jun dimerization protein 2

chrX_-_153360789 0.771 NM_006014
LAGE3
L antigen family, member 3
chr22_-_18807805 0.769 PI4KAP2
PI4KAP1
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
chr5_-_904100 0.769 NM_024786
ZDHHC11
zinc finger, DHHC-type containing 11
chr22_+_35639564 0.764 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr2_+_42649348 0.764 MTA3
metastasis associated 1 family, member 3
chr19_-_6542012 0.762 CD70
CD70 molecule
chr7_-_149960612 0.762 NM_024711
GIMAP6
GTPase, IMAP family member 6
chr5_+_27508139 0.760 LOC643401
hypothetical protein LOC643401
chr15_-_62125562 0.757 NM_014326
DAPK2
death-associated protein kinase 2
chr16_-_960796 0.755 LMF1
lipase maturation factor 1
chr16_-_88251617 0.754 CHMP1A
chromatin modifying protein 1A
chr20_-_50241930 0.753 NM_018197
NM_022088
NM_199426
NM_199427
ZFP64



zinc finger protein 64 homolog (mouse)



chr10_+_26767268 0.752 NM_019043
APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr2_+_42649105 0.751 NM_020744
MTA3
metastasis associated 1 family, member 3
chr16_+_29374479 0.747 NM_001017389
NM_003166
SULT1A4
SULT1A3
SLX1B
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr19_+_11936868 0.744 NM_001012753
ZNF763
zinc finger protein 763
chr11_-_72141064 0.743 NM_001040118
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr22_+_36008369 0.741 NM_013385
CYTH4
cytohesin 4
chr20_+_41729122 0.740 NM_002466
MYBL2
v-myb myeloblastosis viral oncogene homolog (avian)-like 2
chr17_+_77783432 0.738 NM_001042423
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr1_-_92721633 0.736 GFI1
growth factor independent 1 transcription repressor
chr16_-_87297525 0.731 NM_001171816
RNF166
ring finger protein 166
chr19_+_40824486 0.727 NM_014209
ETV2
ets variant 2
chr1_-_16843764 0.724 CROCCP2
ciliary rootlet coiled-coil, rootletin pseudogene 2
chr4_-_647424 0.722


chr20_+_30813851 0.722 NM_006892
NM_175848
NM_175849
DNMT3B


DNA (cytosine-5-)-methyltransferase 3 beta


chr1_-_153109349 0.722 NM_002249
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.33 2.32e-02 GO:0002376 immune system process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.04 9.02e-03 GO:0003823 antigen binding