Motif ID: RREB1.p2

Z-value: 2.147


Transcription factors associated with RREB1.p2:

Gene SymbolEntrez IDGene Name
RREB1 6239 ras responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RREB1chr6_+_70527980.351.9e-01Click!


Activity profile for motif RREB1.p2.

activity profile for motif RREB1.p2


Sorted Z-values histogram for motif RREB1.p2

Sorted Z-values for motif RREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RREB1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_96924582 5.562 NM_001172667
FAM178B
family with sequence similarity 178, member B
chrX_+_151617900 4.337 NM_005363
NM_175868
MAGEA6

melanoma antigen family A, 6

chrX_-_151688850 4.255 NM_005362
MAGEA3
melanoma antigen family A, 3
chr1_-_30977931 3.703 LAPTM5
lysosomal protein transmembrane 5
chrX_-_151653756 2.973 NM_001166386
NM_001166387
NM_005367
MAGEA12


melanoma antigen family A, 12


chr11_-_74740298 2.894 NM_004041
NM_020251
ARRB1

arrestin, beta 1

chrX_+_151653874 2.740 NM_001102576
NM_153478
CSAG1

chondrosarcoma associated gene 1

chrX_+_151633730 2.727 NM_005361
NM_175742
NM_175743
MAGEA2


melanoma antigen family A, 2


chr7_-_100331417 2.414 NM_000665
NM_015831
ACHE

acetylcholinesterase

chrX_-_152139267 2.347 NM_004988
MAGEA1
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr17_-_44058612 2.319 NM_024017
HOXB9
homeobox B9
chr14_+_28305922 2.311 NM_005249
FOXG1
forkhead box G1
chrX_-_151672985 2.307 NM_005361
NM_175742
NM_175743
MAGEA2


melanoma antigen family A, 2


chr4_-_109308893 2.204 NM_001130713
NM_001130714
NM_016269
LEF1


lymphoid enhancer-binding factor 1


chr22_-_21231421 1.924 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr1_-_154318412 1.865 NM_001093725
MEX3A
mex-3 homolog A (C. elegans)
chr20_-_22512893 1.856 FOXA2
forkhead box A2
chr20_-_55533544 1.856 NM_080618
CTCFL
CCCTC-binding factor (zinc finger protein)-like
chr1_-_182273114 1.618 GLT25D2
glycosyltransferase 25 domain containing 2
chr12_+_54700955 1.612 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr19_+_659766 1.604 NM_001040134
NM_002579
PALM

paralemmin

chr13_-_113066366 1.574 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr22_+_19699441 1.537 NM_001159554
NM_005446
P2RX6

purinergic receptor P2X, ligand-gated ion channel, 6

chr20_-_22513050 1.529 NM_021784
FOXA2
forkhead box A2
chr2_+_200031333 1.504


chr15_+_74416156 1.496 NM_145805
ISL2
ISL LIM homeobox 2
chr8_+_144706699 1.468 NM_001166237
GSDMD
gasdermin D
chr4_-_809879 1.451 NM_006651
CPLX1
complexin 1
chr19_-_8581559 1.444 NM_030957
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr19_+_60487345 1.438 NM_032430
BRSK1
BR serine/threonine kinase 1
chr15_+_74416129 1.425 ISL2
ISL LIM homeobox 2
chr21_-_43369492 1.422 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chr13_-_113066202 1.409 GRTP1
growth hormone regulated TBC protein 1
chr7_-_100077072 1.396 NM_003227
TFR2
transferrin receptor 2
chr20_+_48032918 1.389 NM_005985
SNAI1
snail homolog 1 (Drosophila)
chr21_-_43368963 1.387 NM_000071
CBS
cystathionine-beta-synthase
chr12_+_6807831 1.373 NM_014262
LEPREL2
leprecan-like 2
chr12_-_52980914 1.364 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr1_-_1283770 1.363 NM_032348
MXRA8
matrix-remodelling associated 8
chr12_-_52980984 1.355 NM_001136023
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr5_+_176446425 1.334 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr20_-_62151216 1.326 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr7_+_150390566 1.316 SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr9_-_122679387 1.284 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr19_+_14405216 1.280 PKN1
protein kinase N1
chr9_-_122679283 1.273 PHF19
PHD finger protein 19
chr11_+_46359821 1.265 MDK
midkine (neurite growth-promoting factor 2)
chr2_+_174907914 1.263 NM_001145250
SP9
Sp9 transcription factor homolog (mouse)
chr11_+_46359855 1.262 MDK
midkine (neurite growth-promoting factor 2)
chr7_-_150305933 1.245 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr6_+_14032655 1.235 NM_001165034
RNF182
ring finger protein 182
chr19_+_811615 1.227 CFD
complement factor D (adipsin)
chr16_+_86193993 1.199 NM_020655
JPH3
junctophilin 3
chr5_+_6501735 1.189 NM_001145161
UBE2QL1
ubiquitin-conjugating enzyme E2Q family-like 1
chr11_+_46359836 1.181 MDK
midkine (neurite growth-promoting factor 2)
chr12_+_56135353 1.136 NM_031479
INHBE
inhibin, beta E
chr6_-_29703725 1.130 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr19_-_60350122 1.111 TNNT1
troponin T type 1 (skeletal, slow)
chr19_+_60487578 1.093 BRSK1
BR serine/threonine kinase 1
chr17_+_77582774 1.089 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr17_-_44010543 1.088 NM_024015
HOXB4
homeobox B4
chr16_+_29725311 1.085 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr5_+_139008667 1.067 CXXC5
CXXC finger protein 5
chr16_-_69030421 1.059 NM_006927
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr6_+_42857540 1.056 KIAA0240
KIAA0240
chr17_+_63252704 1.053 BPTF
bromodomain PHD finger transcription factor
chr2_-_220144511 1.049 NM_001173408
NM_001173431
NM_015311
OBSL1


obscurin-like 1


chrX_-_39841599 1.047 NM_001123385
NM_017745
BCOR

BCL6 corepressor

chr14_-_20563698 1.032 NDRG2
NDRG family member 2
chr9_+_129962292 1.026 NM_024112
C9orf16
chromosome 9 open reading frame 16
chr2_-_119322228 1.018 NM_001426
EN1
engrailed homeobox 1
chr5_-_176833197 1.015 DBN1
drebrin 1
chr11_+_46359878 1.015 NM_001012333
MDK
midkine (neurite growth-promoting factor 2)
chr9_-_126945536 1.006 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr5_+_139008139 1.005 CXXC5
CXXC finger protein 5
chr17_-_73636362 1.005 TMC6
transmembrane channel-like 6
chr11_+_46359781 1.003 NM_002391
MDK
midkine (neurite growth-promoting factor 2)
chrX_-_153632355 1.001 NM_001081573
NM_080612
GAB3

GRB2-associated binding protein 3

chr17_+_1580504 0.999 WDR81
WD repeat domain 81
chr2_+_181553613 0.998 UBE2E3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr19_+_14405100 0.987 NM_002741
PKN1
protein kinase N1
chr17_-_77474597 0.982 NM_032711
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chrX_-_148476903 0.982 NM_005365
NM_001080790
MAGEA9
MAGEA9B
melanoma antigen family A, 9
melanoma antigen family A, 9B
chr10_+_21863099 0.976 NM_001195627
NM_001195628
NM_001195630
NM_004641
MLLT10



myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10



chr21_-_46428728 0.969 C21orf56
chromosome 21 open reading frame 56
chr9_+_70509925 0.968 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr6_+_32229599 0.957 NM_005155
PPT2-EGFL8
PPT2
PPT2-EGFL8 read-through transcript
palmitoyl-protein thioesterase 2
chr2_-_200030944 0.955 NM_001172509
SATB2
SATB homeobox 2
chr12_-_21818881 0.951 NM_004982
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr17_-_73636386 0.947 NM_001127198
TMC6
transmembrane channel-like 6
chr7_-_150411345 0.946 NM_031434
TMUB1
transmembrane and ubiquitin-like domain containing 1
chr21_-_46428768 0.936 C21orf56
chromosome 21 open reading frame 56
chr16_+_84202515 0.930 NM_001134473
KIAA0182
KIAA0182
chr14_-_20563722 0.928 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr3_+_20056527 0.925 NM_003884
KAT2B
K(lysine) acetyltransferase 2B
chr6_-_35572694 0.918 NM_003214
TEAD3
TEA domain family member 3
chr10_-_76538859 0.918 NM_001007271
NM_001007272
NM_001007273
DUSP13


dual specificity phosphatase 13


chr15_+_41597097 0.912 NM_002373
MAP1A
microtubule-associated protein 1A
chr2_-_130603264 0.904 NM_001099771
POTEF
POTE ankyrin domain family, member F
chr3_-_159306214 0.902


chr17_+_75366524 0.886 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr1_+_20385164 0.886 NM_152376
UBXN10
UBX domain protein 10
chrX_+_152561086 0.884 NM_001395
DUSP9
dual specificity phosphatase 9
chrX_+_119176494 0.882 NM_001099685
NM_032498
RHOXF2B
RHOXF2
Rhox homeobox family, member 2B
Rhox homeobox family, member 2
chrX_+_117513899 0.877 NM_144658
DOCK11
dedicator of cytokinesis 11
chr6_+_32229771 0.864 PPT2-EGFL8
PPT2
PPT2-EGFL8 read-through transcript
palmitoyl-protein thioesterase 2
chr14_-_21064182 0.857 SALL2
sal-like 2 (Drosophila)
chr21_-_10120690 0.855 NM_001187
NM_182484
NM_181704
NM_182481
NM_182482
BAGE
BAGE5
BAGE4
BAGE3
BAGE2
B melanoma antigen
B melanoma antigen family, member 5
B melanoma antigen family, member 4
B melanoma antigen family, member 3
B melanoma antigen family, member 2
chr16_-_28515868 0.852 NM_001054
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr12_+_56202874 0.850 NM_052897
MBD6
methyl-CpG binding domain protein 6
chr3_+_20056857 0.848 KAT2B
K(lysine) acetyltransferase 2B
chr21_-_46428788 0.837 NM_001142854
NM_032261
C21orf56

chromosome 21 open reading frame 56

chr3_+_148593911 0.835


chr1_+_945331 0.830 NM_198576
AGRN
agrin
chr6_+_32230172 0.827 PPT2
palmitoyl-protein thioesterase 2
chr5_+_665454 0.827 CEP72
centrosomal protein 72kDa
chrX_-_11194015 0.825 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr3_-_71715431 0.822 NM_001012505
NM_032682
FOXP1

forkhead box P1

chr11_+_279113 0.814 NM_025092
ATHL1
ATH1, acid trehalase-like 1 (yeast)
chr2_-_144994349 0.814 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr5_+_665404 0.812 NM_018140
CEP72
centrosomal protein 72kDa
chr7_-_733401 0.803 NM_001164760
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr5_+_139008091 0.799 CXXC5
CXXC finger protein 5
chr19_+_17723285 0.793 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr11_-_32413486 0.789 WT1
Wilms tumor 1
chr2_+_181553333 0.778 NM_182678
NM_006357
UBE2E3

ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)

chr7_+_733182 0.772 HEATR2
HEAT repeat containing 2
chr19_+_540849 0.770 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr19_-_55763091 0.761 NM_001080457
LRRC4B
leucine rich repeat containing 4B
chr5_-_134397740 0.760 NM_002653
PITX1
paired-like homeodomain 1
chr1_-_200397300 0.756 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr10_-_75085754 0.753 NM_001114133
SYNPO2L
synaptopodin 2-like
chr19_+_12805747 0.751 MAST1
microtubule associated serine/threonine kinase 1
chr19_-_60350118 0.751 TNNT1
troponin T type 1 (skeletal, slow)
chr16_+_66022520 0.742 NM_000196
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr14_+_104267270 0.742 NM_199165
ADSSL1
adenylosuccinate synthase like 1
chr5_+_76181581 0.741 NM_130772
S100Z
S100 calcium binding protein Z
chr19_-_7896974 0.741 NM_206833
CTXN1
cortexin 1
chrX_-_119095544 0.740 NM_001099685
NM_032498
RHOXF2B
RHOXF2
Rhox homeobox family, member 2B
Rhox homeobox family, member 2
chr2_+_42128521 0.740 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr2_-_144994038 0.739 ZEB2
zinc finger E-box binding homeobox 2
chr12_+_56291484 0.739 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr1_-_149214063 0.738 NM_022075
NM_181746
LASS2

LAG1 homolog, ceramide synthase 2

chr2_+_181553783 0.737 UBE2E3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr19_+_40213431 0.734 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr7_-_148211533 0.733 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr6_+_4721825 0.732 CDYL
chromodomain protein, Y-like
chrX_+_148671394 0.730 NM_005365
NM_001080790
MAGEA9
MAGEA9B
melanoma antigen family A, 9
melanoma antigen family A, 9B
chr9_+_138760432 0.720 LOC100128593
hypothetical LOC100128593
chr15_-_80125403 0.716 NM_032246
MEX3B
mex-3 homolog B (C. elegans)
chr1_-_2115950 0.715 NM_182533
C1orf86
chromosome 1 open reading frame 86
chr19_+_10261646 0.709 NM_003259
ICAM5
intercellular adhesion molecule 5, telencephalin
chr14_-_20562962 0.706 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr6_-_29703913 0.704 NM_021903
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr14_-_90352513 0.702 NM_001010854
TTC7B
tetratricopeptide repeat domain 7B
chr2_-_144991556 0.700 ZEB2
zinc finger E-box binding homeobox 2
chr7_-_150306169 0.699 KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr3_-_187025438 0.698 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr12_-_47679176 0.697 NM_015086
DDN
dendrin
chrX_-_153534951 0.686 NM_020994
NM_172377
CTAG2

cancer/testis antigen 2

chr3_-_185578621 0.685 NM_000460
NM_001177597
NM_001177598
THPO


thrombopoietin


chr16_+_84204424 0.685 NM_014615
KIAA0182
KIAA0182
chr17_-_39700960 0.678 NM_000342
SLC4A1
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)
chr7_+_64136078 0.676 CCT6P3
chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr10_+_21863272 0.674 MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr19_-_60352369 0.673 NM_001126132
NM_001126133
NM_003283
TNNT1


troponin T type 1 (skeletal, slow)


chr11_+_359723 0.672 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr14_-_90352395 0.671


chr7_+_128219307 0.667 NM_022742
CCDC136
coiled-coil domain containing 136
chr19_-_43498386 0.666 NM_001039672
NM_001039673
NM_001145463
YIF1B


Yip1 interacting factor homolog B (S. cerevisiae)


chr1_-_38243716 0.661 FHL3
four and a half LIM domains 3
chr16_+_2807228 0.658 PRSS21
protease, serine, 21 (testisin)
chr19_+_61344501 0.653 ZNF444
zinc finger protein 444
chr10_+_22649977 0.650 NM_005180
BMI1
BMI1 polycomb ring finger oncogene
chr1_-_21850874 0.649 NM_001145658
RAP1GAP
RAP1 GTPase activating protein
chr12_+_46133 0.647 NM_001170738
IQSEC3
IQ motif and Sec7 domain 3
chr8_-_125252884 0.646 C8orf78
chromosome 8 open reading frame 78
chr17_-_71352090 0.646 UNC13D
unc-13 homolog D (C. elegans)
chr8_-_145671947 0.644 FOXH1
forkhead box H1
chr6_+_143423723 0.639 AIG1
androgen-induced 1
chr8_+_41804946 0.635


chr3_-_187025501 0.634 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr5_+_139008209 0.633 NM_016463
CXXC5
CXXC finger protein 5
chr16_+_387176 0.631 NM_005009
NME4
non-metastatic cells 4, protein expressed in
chr15_-_20637731 0.625 NM_144599
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr11_+_2279932 0.619 TSPAN32
tetraspanin 32
chr16_+_2742606 0.618 SRRM2
serine/arginine repetitive matrix 2
chr10_+_21863579 0.617 NM_001195626
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr20_-_49592444 0.617 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr5_-_138746840 0.617 SLC23A1
solute carrier family 23 (nucleobase transporters), member 1
chr10_+_22650145 0.616 BMI1
BMI1 polycomb ring finger oncogene
chrX_+_128501862 0.616 NM_000276
NM_001587
OCRL

oculocerebrorenal syndrome of Lowe

chr2_+_233443237 0.616 NM_206895
C2orf82
chromosome 2 open reading frame 82
chr3_+_23822353 0.615 NM_003341
NM_182666
UBE2E1

ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)

chr4_-_174686918 0.615 HAND2
heart and neural crest derivatives expressed 2
chr2_-_220144427 0.613 OBSL1
obscurin-like 1
chr1_+_110012166 0.611 NM_000848
NM_001142368
GSTM2

glutathione S-transferase mu 2 (muscle)

chr16_+_665680 0.610 RHBDL1
rhomboid, veinlet-like 1 (Drosophila)
chr7_+_100792841 0.608 NM_133457
EMID2
EMI domain containing 2
chr6_-_68655708 0.608



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.89 3.92e-11 GO:0016568 chromatin modification
1.12 2.10e-08 GO:0065007 biological regulation
1.22 3.43e-08 GO:0031323 regulation of cellular metabolic process
1.46 4.59e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.26 8.78e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21 1.40e-07 GO:0080090 regulation of primary metabolic process
1.25 1.91e-07 GO:0051171 regulation of nitrogen compound metabolic process
1.19 4.94e-07 GO:0019222 regulation of metabolic process
1.56 5.01e-07 GO:0051276 chromosome organization
1.62 1.51e-06 GO:0006325 chromatin organization
1.19 1.61e-06 GO:0032502 developmental process
1.12 3.12e-06 GO:0050789 regulation of biological process
1.20 3.34e-06 GO:0007275 multicellular organismal development
1.27 3.48e-06 GO:0048523 negative regulation of cellular process
1.07 3.79e-06 GO:0009987 cellular process
1.26 4.89e-06 GO:0051252 regulation of RNA metabolic process
1.20 6.76e-06 GO:0060255 regulation of macromolecule metabolic process
1.23 1.64e-05 GO:0010468 regulation of gene expression
1.12 1.80e-05 GO:0050794 regulation of cellular process
1.22 2.45e-05 GO:0031326 regulation of cellular biosynthetic process
1.24 2.64e-05 GO:0048519 negative regulation of biological process
1.22 3.27e-05 GO:0009889 regulation of biosynthetic process
1.20 4.20e-05 GO:0048856 anatomical structure development
1.92 4.25e-05 GO:0016569 covalent chromatin modification
1.30 6.28e-05 GO:0007399 nervous system development
1.90 1.24e-04 GO:0016570 histone modification
1.22 1.54e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.20 1.96e-04 GO:0048731 system development
1.23 3.53e-04 GO:0006355 regulation of transcription, DNA-dependent
1.35 5.65e-04 GO:0009892 negative regulation of metabolic process
1.42 5.78e-04 GO:0009890 negative regulation of biosynthetic process
1.27 5.83e-04 GO:0006996 organelle organization
1.43 6.19e-04 GO:0010628 positive regulation of gene expression
1.21 6.31e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.51 6.35e-04 GO:0019226 transmission of nerve impulse
1.51 6.35e-04 GO:0035637 multicellular organismal signaling
1.43 8.16e-04 GO:0051254 positive regulation of RNA metabolic process
1.36 8.44e-04 GO:0031324 negative regulation of cellular metabolic process
1.42 8.88e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.31 1.16e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.47 1.36e-03 GO:0051253 negative regulation of RNA metabolic process
1.44 1.72e-03 GO:0010629 negative regulation of gene expression
1.52 1.77e-03 GO:0007268 synaptic transmission
1.19 1.79e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.47 1.83e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.38 2.54e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26 2.70e-03 GO:0009653 anatomical structure morphogenesis
1.11 2.78e-03 GO:0044237 cellular metabolic process
1.23 2.86e-03 GO:0048513 organ development
1.47 2.88e-03 GO:0007417 central nervous system development
1.14 3.39e-03 GO:0044260 cellular macromolecule metabolic process
1.42 3.39e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.42 3.81e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.48 4.03e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.34 4.04e-03 GO:0048468 cell development
1.40 4.24e-03 GO:0045595 regulation of cell differentiation
1.52 4.25e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.21 4.26e-03 GO:0065008 regulation of biological quality
1.28 4.31e-03 GO:0009893 positive regulation of metabolic process
1.18 5.08e-03 GO:0048518 positive regulation of biological process
1.33 5.32e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.41 5.63e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.36 6.09e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.40 6.15e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.41 6.56e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35 7.39e-03 GO:0051128 regulation of cellular component organization
1.28 7.79e-03 GO:0031325 positive regulation of cellular metabolic process
1.38 7.84e-03 GO:0030182 neuron differentiation
1.61 9.59e-03 GO:0061061 muscle structure development
1.10 1.27e-02 GO:0044238 primary metabolic process
1.67 1.33e-02 GO:0071375 cellular response to peptide hormone stimulus
1.33 1.36e-02 GO:0048699 generation of neurons
1.51 1.84e-02 GO:0007420 brain development
1.16 1.87e-02 GO:0034641 cellular nitrogen compound metabolic process
1.15 1.94e-02 GO:0016043 cellular component organization
1.39 2.53e-02 GO:0009887 organ morphogenesis
1.31 2.84e-02 GO:0022008 neurogenesis
1.18 2.97e-02 GO:0048522 positive regulation of cellular process
1.11 3.11e-02 GO:0043170 macromolecule metabolic process
1.14 3.25e-02 GO:0071840 cellular component organization or biogenesis
1.17 3.62e-02 GO:0071842 cellular component organization at cellular level
1.09 3.94e-02 GO:0008152 metabolic process
1.35 4.09e-02 GO:0009790 embryo development
1.28 4.63e-02 GO:0007154 cell communication
1.58 4.64e-02 GO:0045596 negative regulation of cell differentiation
1.15 4.78e-02 GO:0006807 nitrogen compound metabolic process
1.48 4.93e-02 GO:0048598 embryonic morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.16 3.16e-09 GO:0005634 nucleus
1.08 1.65e-08 GO:0044424 intracellular part
1.07 3.45e-08 GO:0005622 intracellular
1.08 2.26e-06 GO:0043226 organelle
1.27 2.43e-06 GO:0031981 nuclear lumen
1.08 3.41e-06 GO:0043229 intracellular organelle
1.25 3.77e-06 GO:0044428 nuclear part
1.23 1.45e-05 GO:0043233 organelle lumen
1.09 1.46e-05 GO:0043227 membrane-bounded organelle
1.09 1.88e-05 GO:0043231 intracellular membrane-bounded organelle
1.22 3.34e-05 GO:0031974 membrane-enclosed lumen
1.22 8.29e-05 GO:0070013 intracellular organelle lumen
1.18 8.46e-05 GO:0043234 protein complex
1.28 3.35e-04 GO:0005654 nucleoplasm
1.36 1.13e-03 GO:0044451 nucleoplasm part
2.04 2.89e-03 GO:0016585 chromatin remodeling complex
1.14 3.92e-03 GO:0032991 macromolecular complex
1.10 9.36e-03 GO:0044422 organelle part
2.54 9.38e-03 GO:0000118 histone deacetylase complex
1.07 1.40e-02 GO:0005737 cytoplasm
3.30 1.51e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
1.18 1.66e-02 GO:0005829 cytosol
1.09 2.88e-02 GO:0044446 intracellular organelle part
3.54 3.04e-02 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex
3.13 3.33e-02 GO:0031519 PcG protein complex
3.71 4.08e-02 GO:0042627 chylomicron
1.99 4.64e-02 GO:0042383 sarcolemma

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 1.15e-15 GO:0005515 protein binding
1.56 4.26e-09 GO:0043565 sequence-specific DNA binding
1.43 2.64e-08 GO:0030528 transcription regulator activity
1.07 3.94e-08 GO:0005488 binding
1.37 1.91e-05 GO:0001071 nucleic acid binding transcription factor activity
1.37 1.91e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.62 2.61e-04 GO:0016564 transcription repressor activity
1.74 1.11e-03 GO:0010843 promoter binding
1.16 1.42e-03 GO:0003676 nucleic acid binding
1.19 2.20e-03 GO:0003677 DNA binding
1.72 2.63e-03 GO:0003682 chromatin binding
1.69 2.66e-03 GO:0000975 regulatory region DNA binding
1.69 2.66e-03 GO:0001067 regulatory region nucleic acid binding
1.69 2.66e-03 GO:0044212 transcription regulatory region DNA binding
2.17 4.57e-03 GO:0042393 histone binding
3.15 1.28e-02 GO:0035064 methylated histone residue binding