Motif ID: TBP.p2

Z-value: 1.216


Transcription factors associated with TBP.p2:

Gene SymbolEntrez IDGene Name
TBP 6908 TATA box binding protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TBPchr6_+_170705345-0.611.1e-02Click!


Activity profile for motif TBP.p2.

activity profile for motif TBP.p2


Sorted Z-values histogram for motif TBP.p2

Sorted Z-values for motif TBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBP.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_24869945 4.750 NM_006158
NEFL
neurofilament, light polypeptide
chr13_-_52320774 3.985 NM_002590
NM_032949
PCDH8

protocadherin 8

chr17_-_10265991 3.209 NM_002472
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr6_+_27208763 2.855 NM_021064
HIST1H2AG
histone cluster 1, H2ag
chr6_-_137857213 2.837 NM_175747
OLIG3
oligodendrocyte transcription factor 3
chr7_+_127668566 2.780 NM_000230
LEP
leptin
chr1_-_148124738 2.679 NM_003528
HIST2H2BE
histone cluster 2, H2be
chr20_-_38751289 2.451 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr11_-_2863536 2.440 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr21_-_42608774 2.433 NM_003226
TFF3
trefoil factor 3 (intestinal)
chr15_-_61461127 2.428 NM_001218
NM_206925
CA12

carbonic anhydrase XII

chr12_-_51173238 2.408 NM_005554
KRT6A
keratin 6A
chr11_+_43920385 2.400 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr5_-_153837975 2.392 HAND1
heart and neural crest derivatives expressed 1
chr19_-_18763077 2.375 NM_000095
COMP
cartilage oligomeric matrix protein
chr1_+_150997129 2.358 NM_001025231
KPRP
keratinocyte proline-rich protein
chr11_+_60391590 2.330 NM_207341
ZP1
zona pellucida glycoprotein 1 (sperm receptor)
chr1_+_17507276 2.299 NM_012387
PADI4
peptidyl arginine deiminase, type IV
chr6_+_27222839 2.281 NM_080596
HIST1H2AH
histone cluster 1, H2ah
chr15_+_60146467 2.269 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chrX_-_30237403 2.246 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr2_-_219566364 2.220 NM_005209
NM_057093
NM_057094
CRYBA2


crystallin, beta A2


chr1_+_148090804 2.214 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr3_+_42702014 2.198 NM_152393
KBTBD5
kelch repeat and BTB (POZ) domain containing 5
chr16_-_55259405 2.137 NM_005950
MT1G
metallothionein 1G
chr6_-_133076873 2.132 NM_004666
VNN1
vanin 1
chr11_-_18226743 2.127 NM_001127380
NM_030754
SAA2

serum amyloid A2

chr8_-_143692814 2.085 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr8_+_24827173 2.080 NM_005382
NEFM
neurofilament, medium polypeptide
chr1_+_17448179 2.067 NM_016233
PADI3
peptidyl arginine deiminase, type III
chr17_-_36792161 2.024 NM_021013
KRT34
keratin 34
chr12_+_48630790 2.017 NM_000486
AQP2
aquaporin 2 (collecting duct)
chr8_+_24827181 1.997 NEFM
neurofilament, medium polypeptide
chr11_-_93774223 1.994 NM_016540
GPR83
G protein-coupled receptor 83
chr1_-_167969802 1.979 NM_000450
SELE
selectin E
chr2_-_151052391 1.977 NM_005168
RND3
Rho family GTPase 3
chr3_+_62279707 1.972 C3orf14
chromosome 3 open reading frame 14
chr1_-_148050534 1.969 NM_001024599
NM_001161334
HIST2H2BF

histone cluster 2, H2bf

chr15_-_61460967 1.967 CA12
carbonic anhydrase XII
chr17_-_36436979 1.962 NM_031957
KRTAP1-5
keratin associated protein 1-5
chr19_+_12763295 1.927 NM_002229
JUNB
jun B proto-oncogene
chr21_+_46342440 1.914 NM_001849
NM_058174
NM_058175
COL6A2


collagen, type VI, alpha 2


chr17_-_59342319 1.903 NM_001318
NM_022579
NM_022580
NM_022581
CSHL1



chorionic somatomammotropin hormone-like 1



chr4_+_119419354 1.888 SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr17_-_36276987 1.844 NM_000223
KRT12
keratin 12
chr8_+_133948384 1.840 NM_003235
TG
thyroglobulin
chr11_+_1064869 1.827 NM_002457
MUC2
mucin 2, oligomeric mucus/gel-forming
chr12_-_55134692 1.820 NM_012064
MIP
major intrinsic protein of lens fiber
chr19_+_12763285 1.820 JUNB
jun B proto-oncogene
chr22_+_28206180 1.819 NM_021076
NEFH
neurofilament, heavy polypeptide
chr6_+_127940011 1.818 NM_001010905
C6orf58
chromosome 6 open reading frame 58
chr15_-_60244773 1.813 NM_001007595
C2CD4B
C2 calcium-dependent domain containing 4B
chr16_-_21130368 1.808 NM_003460
ZP2
zona pellucida glycoprotein 2 (sperm receptor)
chr11_+_65945050 1.803 NM_178864
NPAS4
neuronal PAS domain protein 4
chr21_-_44795769 1.785 NM_198693
KRTAP10-2
keratin associated protein 10-2
chr5_+_149526533 1.773 NM_001804
CDX1
caudal type homeobox 1
chr9_+_91409746 1.767 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr6_+_26264531 1.728 HIST1H1E
histone cluster 1, H1e
chr4_+_75393053 1.717 NM_001013442
EPGN
epithelial mitogen homolog (mouse)
chr1_-_2451543 1.705 NM_001010926
HES5
hairy and enhancer of split 5 (Drosophila)
chr12_-_51298599 1.703 NM_175068
KRT73
keratin 73
chr11_-_60886038 1.674 NM_001161454
NM_153611
CYBASC3

cytochrome b, ascorbate dependent 3

chr1_+_148089251 1.664 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr11_-_102156531 1.663 NM_002425
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr4_-_75183700 1.658 CXCL2
chemokine (C-X-C motif) ligand 2
chr9_+_135491305 1.653 NM_000787
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr9_+_129951552 1.653 NM_005564
LCN2
lipocalin 2
chrX_-_139414890 1.651 NM_005634
SOX3
SRY (sex determining region Y)-box 3
chr2_-_238813284 1.640 HES6
hairy and enhancer of split 6 (Drosophila)
chr3_-_130517759 1.638 NM_006026
H1FX
H1 histone family, member X
chr1_+_151147646 1.636 NM_005547
IVL
involucrin
chr6_-_26125939 1.633 NM_005325
HIST1H1A
histone cluster 1, H1a
chr1_-_148051859 1.621 NM_001123375
HIST2H3D
histone cluster 2, H3d
chr17_-_36181927 1.619 NM_181539
KRT26
keratin 26
chr11_-_102331643 1.608 NM_002427
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr21_-_27139143 1.606 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr19_-_38485269 1.600 NM_004364
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr17_-_36594652 1.555 NM_033060
KRTAP4-1
keratin associated protein 4-1
chr16_+_55273879 1.544 NM_005952
MT1X
metallothionein 1X
chr19_-_38485281 1.540 CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr19_+_38485583 1.539 LOC80054
hypothetical LOC80054
chr12_-_51332214 1.538 NM_000423
KRT2
keratin 2
chr15_-_83002421 1.535 NMB
neuromedin B
chr5_+_132037271 1.529 NM_000589
NM_172348
IL4

interleukin 4

chr5_+_131424245 1.524 NM_000588
IL3
interleukin 3 (colony-stimulating factor, multiple)
chr1_-_41100589 1.521 NM_133467
CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr21_-_27139563 1.520 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr2_-_25245062 1.507 NM_000939
NM_001035256
POMC

proopiomelanocortin

chrX_-_133620103 1.506 NM_021796
PLAC1
placenta-specific 1
chr1_-_150398327 1.483 NM_001122965
RPTN
repetin
chr11_-_2907169 1.479 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr20_+_2224612 1.458 NM_003245
TGM3
transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr18_+_19972928 1.450 NM_012189
NM_138643
NM_153768
NM_153769
NM_153770
CABYR




calcium binding tyrosine-(Y)-phosphorylation regulated




chr10_+_118370441 1.447 NM_005396
PNLIPRP2
pancreatic lipase-related protein 2
chr1_-_1139358 1.446 NM_003327
TNFRSF4
tumor necrosis factor receptor superfamily, member 4
chr10_-_71871444 1.433 NM_018055
NODAL
nodal homolog (mouse)
chr17_-_36807322 1.431 NM_002277
KRT31
keratin 31
chr21_+_44844924 1.416 NM_198689
KRTAP10-7
keratin associated protein 10-7
chr1_+_33319287 1.413 NM_052998
ADC
arginine decarboxylase
chr2_-_162717159 1.401 NM_002054
GCG
glucagon
chr20_+_36365965 1.398 NM_001725
BPI
bactericidal/permeability-increasing protein
chr11_-_1576057 1.392 NM_001004325
KRTAP5-2
keratin associated protein 5-2
chr8_-_23317571 1.392 LOXL2
lysyl oxidase-like 2
chr18_+_19973023 1.383 CABYR
calcium binding tyrosine-(Y)-phosphorylation regulated
chr1_+_150749943 1.380 NM_178438
LCE5A
late cornified envelope 5A
chr1_-_154941861 1.374 NM_001878
CRABP2
cellular retinoic acid binding protein 2
chr7_-_128203079 1.370 NM_001708
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr11_+_60727559 1.369 NM_001079807
PGA3
PGA4
pepsinogen 3, group I (pepsinogen A)
pepsinogen 4, group I (pepsinogen A)
chr1_-_148079357 1.364 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr12_-_51476047 1.351 NM_057088
KRT3
keratin 3
chr5_-_54504590 1.349 NM_001145734
NM_001170402
NM_152623
CDC20B


cell division cycle 20 homolog B (S. cerevisiae)


chr17_-_36469869 1.343 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr6_-_26358811 1.342 NM_021018
HIST1H3F
histone cluster 1, H3f
chr1_+_12774132 1.331 NM_023013
PRAMEF1
PRAME family member 1
chr8_-_23317577 1.328 LOXL2
lysyl oxidase-like 2
chrX_+_117841761 1.323 NM_173798
ZCCHC12
zinc finger, CCHC domain containing 12
chr11_-_5212168 1.318 NM_000519
HBD
hemoglobin, delta
chr6_+_26264537 1.317 NM_005321
HIST1H1E
histone cluster 1, H1e
chr5_+_176744037 1.311 NM_001167579
NM_003052
SLC34A1

solute carrier family 34 (sodium phosphate), member 1

chr3_+_150065732 1.308 NM_001870
CPA3
carboxypeptidase A3 (mast cell)
chr6_+_26325124 1.305 NM_021052
HIST1H2AE
histone cluster 1, H2ae
chr17_-_68100537 1.301 LOC100499467
hypothetical LOC100499467
chr2_-_79240293 1.298 NM_138938
NM_002580
NM_138937
REG3A


regenerating islet-derived 3 alpha


chr6_+_26153590 1.291 NM_003531
HIST1H3C
histone cluster 1, H3c
chr1_-_226679648 1.291 NM_003493
HIST3H3
histone cluster 3, H3
chr6_+_33347833 1.289 RPS18
ribosomal protein S18
chr7_+_142723340 1.285 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr6_+_31891293 1.271 HSPA1A
heat shock 70kDa protein 1A
chr17_-_10217046 1.270 NM_003802
MYH13
myosin, heavy chain 13, skeletal muscle
chr4_-_108176901 1.269 NM_014421
DKK2
dickkopf homolog 2 (Xenopus laevis)
chr11_-_102250876 1.268 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chr12_-_50971516 1.265 NM_002281
KRT81
keratin 81
chr1_-_27353987 1.261 NM_003047
SLC9A1
solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr16_-_4232053 1.254 NM_001098814
SRL
sarcalumenin
chr10_-_71871364 1.247 NODAL
nodal homolog (mouse)
chr2_-_238813365 1.247 NM_001142853
NM_018645
HES6

hairy and enhancer of split 6 (Drosophila)

chr3_+_110338250 1.244 FLJ22763
hypothetical LOC401081
chr13_+_52500830 1.239 NM_006418
OLFM4
olfactomedin 4
chr19_+_6482009 1.236 NM_003811
TNFSF9
tumor necrosis factor (ligand) superfamily, member 9
chr1_-_26266571 1.234 NM_032588
TRIM63
tripartite motif containing 63
chr12_-_51132129 1.231 NM_005555
KRT6B
keratin 6B
chr17_-_36113502 1.223 NM_019016
KRT24
keratin 24
chr18_-_42810446 1.222 NM_145653
TCEB3C
transcription elongation factor B polypeptide 3C (elongin A3)
chr14_+_92459244 1.214 CHGA
chromogranin A (parathyroid secretory protein 1)
chr11_-_102001259 1.196 NM_004771
MMP20
matrix metallopeptidase 20
chr17_-_45633986 1.194 NM_000088
COL1A1
collagen, type I, alpha 1
chr11_+_66939720 1.186 NM_001166222
NM_020811
CARNS1

carnosine synthase 1

chr17_-_76064842 1.177 NM_002522
NPTX1
neuronal pentraxin I
chr1_+_144183811 1.176 ANKRD34A
ankyrin repeat domain 34A
chr19_+_7000349 1.154 NM_144614
MBD3L2
methyl-CpG binding domain protein 3-like 2
chr17_+_53670785 1.151 NM_001160102
NM_006151
LPO

lactoperoxidase

chr1_+_157824239 1.151 NM_001639
APCS
amyloid P component, serum
chr8_-_23317536 1.149 LOXL2
lysyl oxidase-like 2
chr2_-_73373956 1.144 NM_001965
EGR4
early growth response 4
chr15_+_30797466 1.139 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr1_+_12839527 1.135 NM_023014
PRAMEF2
PRAME family member 2
chr10_+_94823636 1.134 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr6_-_169395847 1.129 THBS2
thrombospondin 2
chr7_-_16811131 1.122 NM_006408
AGR2
anterior gradient homolog 2 (Xenopus laevis)
chr5_-_53642144 1.115 NM_019087
ARL15
ADP-ribosylation factor-like 15
chr4_-_75123193 1.115 NM_002090
CXCL3
chemokine (C-X-C motif) ligand 3
chr6_-_27907283 1.108 NM_003541
HIST1H4A
HIST1H4F
HIST1H4K
HIST1H4J
histone cluster 1, H4a
histone cluster 1, H4f
histone cluster 1, H4k
histone cluster 1, H4j
chr17_-_36444626 1.089 NM_030966
KRTAP1-3
keratin associated protein 1-3
chr20_+_43269051 1.089 NM_003007
SEMG1
semenogelin I
chrX_-_138114846 1.088 NM_001139498
NM_001139500
NM_001139501
FGF13


fibroblast growth factor 13


chr8_+_1980564 1.087 NM_003970
MYOM2
myomesin (M-protein) 2, 165kDa
chr11_-_6418705 1.086 NM_000613
HPX
hemopexin
chr17_-_59349867 1.074 NM_000515
NM_022559
NM_022560
NM_022561
NM_022562
GH1




growth hormone 1




chr6_+_112775224 1.054 NM_001013734
RFPL4B
ret finger protein-like 4B
chr7_+_24290331 1.052 NM_000905
NPY
neuropeptide Y
chr8_-_133140808 1.040 NM_001080399
OC90
otoconin 90
chr7_+_75769927 1.040 HSPB1
heat shock 27kDa protein 1
chr9_-_116920232 1.037 NM_002160
TNC
tenascin C
chr17_-_36456949 1.034 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr5_+_145698779 1.031 NM_002700
POU4F3
POU class 4 homeobox 3
chr5_-_153838013 1.031 NM_004821
HAND1
heart and neural crest derivatives expressed 1
chr1_-_148080888 1.026 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr14_+_92459197 1.025 NM_001275
CHGA
chromogranin A (parathyroid secretory protein 1)
chr12_+_50913274 1.022 KRT7
keratin 7
chr16_+_55217180 1.022 MT1E
metallothionein 1E
chr21_+_43462209 1.020 NM_000394
CRYAA
crystallin, alpha A
chr5_+_15553288 1.015 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr1_-_151784889 1.010 NM_002961
NM_019554
S100A4

S100 calcium binding protein A4

chr1_+_159495140 1.007 NM_001102566
PCP4L1
Purkinje cell protein 4 like 1
chr11_+_61491793 1.002 LOC399900
hypothetical LOC399900
chr18_-_73834670 1.000


chr1_-_150564302 1.000 NM_002016
FLG
filaggrin
chr1_+_151596953 0.996 NM_002965
S100A9
S100 calcium binding protein A9
chr19_+_627346 0.996 NM_005860
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr18_-_42798364 0.991 NM_001100817
TCEB3C
TCEB3CL
transcription elongation factor B polypeptide 3C (elongin A3)
transcription elongation factor B polypeptide 3C-like
chr6_+_33347776 0.989 NM_022551
RPS18
ribosomal protein S18
chr10_-_69125932 0.989 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr12_-_51281482 0.965 NM_001146225
NM_001146226
NM_080747
KRT72


keratin 72


chr2_+_28572441 0.962 NM_001170585
NM_153021
PLB1

phospholipase B1

chr1_+_161305558 0.957 NM_001113381
RGS4
regulator of G-protein signaling 4
chr6_-_27890496 0.955 NM_021066
HIST1H2AJ
histone cluster 1, H2aj
chr12_-_51153788 0.944 NM_173086
KRT6C
keratin 6C
chr4_-_101090431 0.940 H2AFZ
H2A histone family, member Z
chr17_+_76623553 0.939 BAIAP2
BAI1-associated protein 2
chr4_+_75529716 0.938 NM_001657
AREG
amphiregulin

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
8.38 7.68e-16 GO:0006334 nucleosome assembly
7.83 1.40e-15 GO:0034728 nucleosome organization
7.95 3.66e-15 GO:0031497 chromatin assembly
7.14 2.27e-14 GO:0071824 protein-DNA complex subunit organization
7.28 4.75e-14 GO:0065004 protein-DNA complex assembly
1.49 1.64e-12 GO:0032501 multicellular organismal process
5.89 5.84e-12 GO:0006333 chromatin assembly or disassembly
6.09 7.23e-12 GO:0006323 DNA packaging
2.58 4.02e-11 GO:0009888 tissue development
5.42 5.94e-11 GO:0071103 DNA conformation change
4.69 1.93e-10 GO:0008544 epidermis development
1.92 3.70e-10 GO:0048513 organ development
9.94 8.30e-09 GO:0034614 cellular response to reactive oxygen species
1.61 9.46e-09 GO:0048856 anatomical structure development
3.76 1.04e-08 GO:0010035 response to inorganic substance
1.64 2.66e-08 GO:0048731 system development
1.73 3.98e-08 GO:0042221 response to chemical stimulus
11.92 9.30e-08 GO:0070301 cellular response to hydrogen peroxide
9.27 1.27e-07 GO:0031424 keratinization
5.94 3.07e-07 GO:0000302 response to reactive oxygen species
1.49 3.37e-07 GO:0032502 developmental process
3.34 1.93e-06 GO:0006954 inflammatory response
6.96 2.50e-06 GO:0034599 cellular response to oxidative stress
2.15 4.04e-06 GO:0009611 response to wounding
2.21 4.81e-06 GO:0006952 defense response
1.48 4.92e-06 GO:0007275 multicellular organismal development
11.59 5.50e-06 GO:0042743 hydrogen peroxide metabolic process
6.02 7.03e-06 GO:0009913 epidermal cell differentiation
6.42 8.31e-06 GO:0042542 response to hydrogen peroxide
2.86 1.99e-05 GO:0034622 cellular macromolecular complex assembly
2.52 4.18e-05 GO:0034621 cellular macromolecular complex subunit organization
1.57 4.23e-05 GO:0006950 response to stress
6.09 5.67e-05 GO:0030216 keratinocyte differentiation
2.09 7.19e-05 GO:0043933 macromolecular complex subunit organization
2.46 8.17e-05 GO:0009607 response to biotic stimulus
2.03 1.10e-04 GO:0051704 multi-organism process
2.31 1.13e-04 GO:0009887 organ morphogenesis
12.37 1.19e-04 GO:0042744 hydrogen peroxide catabolic process
7.65 1.38e-04 GO:0072593 reactive oxygen species metabolic process
4.59 1.64e-04 GO:0008217 regulation of blood pressure
1.80 2.06e-04 GO:0051239 regulation of multicellular organismal process
11.13 3.23e-04 GO:0045103 intermediate filament-based process
1.94 4.68e-04 GO:0070887 cellular response to chemical stimulus
3.03 5.05e-04 GO:0009617 response to bacterium
3.38 6.23e-04 GO:0006979 response to oxidative stress
2.09 7.91e-04 GO:0065003 macromolecular complex assembly
2.49 8.84e-04 GO:0051707 response to other organism
1.73 2.07e-03 GO:0010033 response to organic substance
1.90 2.09e-03 GO:0050793 regulation of developmental process
3.13 4.22e-03 GO:0003013 circulatory system process
3.13 4.22e-03 GO:0008015 blood circulation
17.39 4.66e-03 GO:0042738 exogenous drug catabolic process
1.96 5.01e-03 GO:0071844 cellular component assembly at cellular level
1.78 5.66e-03 GO:0022607 cellular component assembly
2.72 6.25e-03 GO:0048545 response to steroid hormone stimulus
2.06 8.07e-03 GO:0009725 response to hormone stimulus
1.50 9.28e-03 GO:0030154 cell differentiation
13.91 1.98e-02 GO:0042737 drug catabolic process
13.91 1.98e-02 GO:0046689 response to mercury ion
3.02 2.07e-02 GO:0030855 epithelial cell differentiation
1.75 2.51e-02 GO:0009605 response to external stimulus
5.15 2.62e-02 GO:0051591 response to cAMP
9.82 2.79e-02 GO:0045104 intermediate filament cytoskeleton organization
1.87 2.84e-02 GO:0007155 cell adhesion
1.87 2.84e-02 GO:0022610 biological adhesion
1.46 3.00e-02 GO:0048869 cellular developmental process
1.21 3.03e-02 GO:0050896 response to stimulus
2.04 3.08e-02 GO:0006928 cellular component movement
1.93 3.32e-02 GO:0009719 response to endogenous stimulus
1.45 3.55e-02 GO:0065008 regulation of biological quality
3.57 4.51e-02 GO:0007565 female pregnancy
6.18 4.74e-02 GO:0044236 multicellular organismal metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
10.50 2.95e-46 GO:0005882 intermediate filament
9.08 9.48e-42 GO:0045111 intermediate filament cytoskeleton
3.42 5.39e-33 GO:0044421 extracellular region part
2.52 2.20e-32 GO:0005576 extracellular region
3.77 4.23e-31 GO:0005615 extracellular space
12.87 1.71e-30 GO:0045095 keratin filament
12.56 2.01e-22 GO:0000786 nucleosome
8.03 3.39e-16 GO:0032993 protein-DNA complex
2.00 1.31e-10 GO:0005856 cytoskeleton
2.19 1.54e-09 GO:0044430 cytoskeletal part
1.65 2.05e-09 GO:0043228 non-membrane-bounded organelle
1.65 2.05e-09 GO:0043232 intracellular non-membrane-bounded organelle
3.70 3.24e-08 GO:0000785 chromatin
2.85 9.79e-07 GO:0031012 extracellular matrix
12.37 1.50e-05 GO:0032982 myosin filament
2.74 7.16e-05 GO:0005578 proteinaceous extracellular matrix
9.27 1.03e-03 GO:0001533 cornified envelope
2.89 1.80e-03 GO:0030141 stored secretory granule
1.32 3.13e-03 GO:0032991 macromolecular complex
11.59 7.37e-03 GO:0005833 hemoglobin complex
2.07 7.94e-03 GO:0044427 chromosomal part
3.12 4.50e-02 GO:0030016 myofibril

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.55 4.35e-20 GO:0005198 structural molecule activity
5.03 1.01e-13 GO:0005125 cytokine activity
2.41 3.36e-12 GO:0005102 receptor binding
6.18 9.10e-10 GO:0005179 hormone activity
4.06 9.63e-08 GO:0005126 cytokine receptor binding
4.46 1.69e-06 GO:0046906 tetrapyrrole binding
4.52 3.06e-06 GO:0020037 heme binding
7.42 9.98e-06 GO:0019825 oxygen binding
7.26 1.31e-05 GO:0008009 chemokine activity
5.49 4.45e-05 GO:0005200 structural constituent of cytoskeleton
6.55 4.55e-05 GO:0042379 chemokine receptor binding
3.68 5.45e-05 GO:0008083 growth factor activity
3.40 2.08e-04 GO:0001664 G-protein-coupled receptor binding
3.08 3.59e-04 GO:0005506 iron ion binding
2.42 6.94e-04 GO:0030246 carbohydrate binding
12.84 8.51e-04 GO:0005344 oxygen transporter activity
22.26 2.49e-03 GO:0046870 cadmium ion binding
5.82 4.85e-03 GO:0008307 structural constituent of muscle
2.75 1.49e-02 GO:0005529 sugar binding
4.91 2.04e-02 GO:0016209 antioxidant activity
1.82 2.91e-02 GO:0005509 calcium ion binding
13.91 3.21e-02 GO:0015250 water channel activity
3.83 3.45e-02 GO:0005201 extracellular matrix structural constituent
5.73 4.99e-02 GO:0004601 peroxidase activity
5.73 4.99e-02 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor