Motif ID: CRX.p2

Z-value: 2.450


Transcription factors associated with CRX.p2:

Gene SymbolEntrez IDGene Name
CRX 1406 cone-rod homeobox

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CRXchr19_+_530169100.371.7e-01Click!


Activity profile for motif CRX.p2.

activity profile for motif CRX.p2


Sorted Z-values histogram for motif CRX.p2

Sorted Z-values for motif CRX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CRX.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_56567839 5.993 NM_199046
NM_199456
TEPP

testis, prostate and placenta expressed

chr1_+_559618 5.040


chr11_+_61473931 4.343 NM_001139443
NM_004183
BEST1

bestrophin 1

chr5_-_134290789 4.288


chr1_+_559129 4.262


chr7_-_99115454 3.725 NM_000777
NM_001190484
CYP3A5

cytochrome P450, family 3, subfamily A, polypeptide 5

chr1_+_226399026 3.078 NM_001159391
GUK1
guanylate kinase 1
chr11_-_5110383 2.869 NM_001005160
OR52A5
olfactory receptor, family 52, subfamily A, member 5
chr3_-_19950675 2.543 NM_144715
EFHB
EF-hand domain family, member B
chr12_-_1898063 2.456 NM_172364
CACNA2D4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr1_-_26266571 2.442 NM_032588
TRIM63
tripartite motif containing 63
chr20_-_48686832 2.294 NM_080829
FAM65C
family with sequence similarity 65, member C
chr1_+_31655607 2.275 NM_001199037
SERINC2
serine incorporator 2
chr11_+_61279436 2.245 NM_013279
C11orf9
chromosome 11 open reading frame 9
chrX_-_70248022 2.155 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr12_+_130004404 2.100 NM_198827
GPR133
G protein-coupled receptor 133
chr9_-_99740243 2.062 NM_197978
HEMGN
hemogen
chr17_+_35718948 2.037 NM_000964
RARA
retinoic acid receptor, alpha
chr10_-_76538859 2.025 NM_001007271
NM_001007272
NM_001007273
DUSP13


dual specificity phosphatase 13


chr6_-_24597717 1.994 NM_177483
NM_001503
GPLD1

glycosylphosphatidylinositol specific phospholipase D1

chr12_-_69434330 1.994 PTPRR
protein tyrosine phosphatase, receptor type, R
chr19_-_60360768 1.924 NM_000363
TNNI3
troponin I type 3 (cardiac)
chr11_-_118405288 1.814 NM_001164280
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr7_+_111850367 1.717 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr19_-_12858956 1.707 NM_006563
KLF1
Kruppel-like factor 1 (erythroid)
chr16_+_56286212 1.705 NM_032269
CCDC135
coiled-coil domain containing 135
chr1_-_239865724 1.682 NM_001821
CHML
choroideremia-like (Rab escort protein 2)
chr7_-_128203079 1.666 NM_001708
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr5_-_39255335 1.665 NM_001465
NM_199335
FYB

FYN binding protein

chr9_+_4829763 1.660 RCL1
RNA terminal phosphate cyclase-like 1
chrX_-_24600661 1.650 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr6_+_10693964 1.644 NM_145655
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chrX_-_129347101 1.633 NM_178471
GPR119
G protein-coupled receptor 119
chr18_+_53865455 1.626 NM_001144964
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr6_-_2696152 1.617 NM_001012418
MYLK4
myosin light chain kinase family, member 4
chr8_+_26206648 1.613 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chrX_-_11194015 1.576 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr3_-_99236520 1.557 NM_001105580
GABRR3
gamma-aminobutyric acid (GABA) receptor, rho 3
chr11_-_59369501 1.533 NM_005142
GIF
gastric intrinsic factor (vitamin B synthesis)
chr19_-_56018815 1.532 NM_002257
KLK1
kallikrein 1
chr21_+_39745649 1.507 NM_007341
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr8_-_38324809 1.496 WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
chr7_-_150352484 1.495 NM_173681
ATG9B
ATG9 autophagy related 9 homolog B (S. cerevisiae)
chr1_+_116744992 1.475 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr1_+_61319976 1.440 NM_001145512
NFIA
nuclear factor I/A
chr21_+_37377116 1.412 NM_003316
TTC3
tetratricopeptide repeat domain 3
chr6_+_47732181 1.411 NM_153839
GPR111
G protein-coupled receptor 111
chr1_-_191422346 1.410 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr12_+_56114724 1.407 NM_005538
INHBC
inhibin, beta C
chr1_-_180621272 1.399 GLUL
glutamate-ammonia ligase
chr3_+_186529376 1.396 MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr17_-_39500512 1.369 NM_152344
LSM12
LSM12 homolog (S. cerevisiae)
chr6_-_49712483 1.356 NM_000324
RHAG
Rh-associated glycoprotein
chr4_+_17125885 1.340 NM_001079827
CLRN2
clarin 2
chr5_-_34020445 1.328 NM_001012509
NM_016180
SLC45A2

solute carrier family 45, member 2

chr12_+_6819635 1.328 NM_002075
GNB3
guanine nucleotide binding protein (G protein), beta polypeptide 3
chr3_-_48015264 1.323 MAP4
microtubule-associated protein 4
chr1_+_202033273 1.317 NM_001174108
ZBED6
zinc finger, BED-type containing 6
chr9_+_132990760 1.316 NM_005085
NUP214
nucleoporin 214kDa
chr1_-_109651140 1.295 NM_001010985
MYBPHL
myosin binding protein H-like
chr19_+_43616167 1.281 NM_000540
NM_001042723
RYR1

ryanodine receptor 1 (skeletal)

chr5_+_76181581 1.277 NM_130772
S100Z
S100 calcium binding protein Z
chr19_-_43926953 1.255 NM_144691
CAPN12
calpain 12
chr19_-_56585603 1.239 NM_001193623
LOC147646
hypothetical protein LOC147646
chr6_-_11887265 1.238 NM_001143948
NM_032744
C6orf105

chromosome 6 open reading frame 105

chr1_-_53380709 1.225 NM_006671
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr7_+_116447499 1.221 ST7
suppression of tumorigenicity 7
chr2_-_157892391 1.215 NM_001009959
ERMN
ermin, ERM-like protein
chr2_-_73781974 1.177 NM_016347
NAT8B
N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)
chr1_-_166149867 1.168 NM_001167749
NM_018417
ADCY10

adenylate cyclase 10 (soluble)

chr1_-_151280201 1.153 NM_006945
SPRR2D
small proline-rich protein 2D
chr10_-_75080784 1.152 NM_024875
SYNPO2L
synaptopodin 2-like
chr7_-_142369519 1.151 KEL
Kell blood group, metallo-endopeptidase
chr17_+_53670785 1.138 NM_001160102
NM_006151
LPO

lactoperoxidase

chr17_-_43390108 1.131 NM_024320
PRR15L
proline rich 15-like
chr6_+_135558572 1.128


chr8_-_86477585 1.120 NM_001128829
NM_001128830
NM_001128831
NM_001738
CA1



carbonic anhydrase I



chr1_+_150005754 1.107 NM_016178
OAZ3
ornithine decarboxylase antizyme 3
chr7_+_116447527 1.107 ST7
suppression of tumorigenicity 7
chrX_-_48655978 1.097 PIM2
pim-2 oncogene
chr20_+_41621079 1.094 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr1_+_35507145 1.088 NM_005095
ZMYM4
zinc finger, MYM-type 4
chr7_-_33047042 1.074 NM_001166118
NM_016489
NT5C3

5'-nucleotidase, cytosolic III

chr7_+_29486010 1.068 NM_001039936
CHN2
chimerin (chimaerin) 2
chrX_-_135783496 1.057


chr2_-_55090759 1.056 NM_007008
RTN4
reticulon 4
chr17_+_35484204 1.054 THRA
thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
chr20_+_41621119 1.053 SGK2
serum/glucocorticoid regulated kinase 2
chr19_-_12802206 1.050 NM_001080997
RTBDN
retbindin
chr8_+_77928372 1.050 ZFHX4
zinc finger homeobox 4
chr12_-_51476047 1.048 NM_057088
KRT3
keratin 3
chr1_+_32512298 1.037 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr1_+_205344200 1.027 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr1_-_47428190 1.017 PDZK1IP1
PDZK1 interacting protein 1
chr20_-_43972061 1.007 PLTP
phospholipid transfer protein
chr20_-_30703219 1.002 NM_182584
C20orf203
chromosome 20 open reading frame 203
chr1_-_33613729 0.989 NM_198040
PHC2
polyhomeotic homolog 2 (Drosophila)
chr2_+_169634330 0.987 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr15_-_41300316 0.982 EPB42
erythrocyte membrane protein band 4.2
chr10_-_15237351 0.980 LOC100192204
peptidylprolyl isomerase A pseudogene
chr7_+_142692165 0.978 NM_153345
TMEM139
transmembrane protein 139
chr10_+_126620681 0.972 NM_017580
ZRANB1
zinc finger, RAN-binding domain containing 1
chr1_-_7923464 0.971 NM_001561
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr2_+_157822355 0.970 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr9_+_96561750 0.967 NM_001193329
C9orf3
chromosome 9 open reading frame 3
chr18_+_606671 0.961 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr10_+_35524060 0.957 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr1_-_156923111 0.956 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr11_-_5178505 0.952 NM_001004760
OR51V1
olfactory receptor, family 51, subfamily V, member 1
chr2_-_180580024 0.947 NM_020943
CWC22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr19_-_47498768 0.945 NM_001145939
NM_001145940
PAFAH1B3

platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)

chr16_-_70080678 0.928 NM_006961
ZNF19
zinc finger protein 19
chrX_+_123307812 0.920 NM_001114937
NM_002351
SH2D1A

SH2 domain containing 1A

chr10_-_82039158 0.913 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chr1_+_357502 0.911 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr1_-_56750235 0.909 PPAP2B
phosphatidic acid phosphatase type 2B
chr6_+_31662454 0.900 NM_205837
LST1
leukocyte specific transcript 1
chr1_-_93030538 0.892 NM_005665
EVI5
ecotropic viral integration site 5
chr6_-_149847809 0.892 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr7_-_142369534 0.883 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr1_-_39119845 0.882 NM_030772
GJA9-MYCBP
GJA9
GJA9-MYCBP read-through transcript
gap junction protein, alpha 9, 59kDa
chr12_-_55730125 0.875 NM_005379
MYO1A
myosin IA
chr12_-_112058403 0.874 NM_001193520
NM_004658
RASAL1

RAS protein activator like 1 (GAP1 like)

chr1_-_47428310 0.874 NM_005764
PDZK1IP1
PDZK1 interacting protein 1
chr6_-_28429950 0.872 NM_145909
ZNF323
zinc finger protein 323
chr20_-_43949644 0.863 NM_080608
C20orf165
chromosome 20 open reading frame 165
chr3_+_138159396 0.862 NM_144717
IL20RB
interleukin 20 receptor beta
chr2_+_33213111 0.857 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr2_+_113591940 0.856 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr11_-_117589283 0.855 NM_153206
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr12_+_49922592 0.851 DAZAP2
DAZ associated protein 2
chr6_+_132000134 0.845 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr1_+_152560179 0.844 NM_080429
AQP10
aquaporin 10
chr20_+_34019942 0.843 NM_080834
C20orf152
chromosome 20 open reading frame 152
chr20_+_1132097 0.838 NM_001009612
C20orf202
chromosome 20 open reading frame 202
chr1_+_179164195 0.836


chr7_-_135263737 0.834 MTPN
LUZP6
myotrophin
leucine zipper protein 6
chr19_-_54219039 0.832 NM_000737
CGB
CGB5
chorionic gonadotropin, beta polypeptide
chorionic gonadotropin, beta polypeptide 5
chr6_+_4835224 0.831 NM_001143971
CDYL
chromodomain protein, Y-like
chr3_+_123526700 0.830 NM_005213
CSTA
cystatin A (stefin A)
chr1_-_153537362 0.829 NM_181871
PKLR
pyruvate kinase, liver and RBC
chr11_-_64284762 0.825 NM_001164716
NM_005609
PYGM

phosphorylase, glycogen, muscle

chr16_-_46823682 0.820 NM_033151
ABCC11
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr20_+_55338221 0.808 NM_012444
NM_198265
SPO11

SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)

chr11_+_94398069 0.808 NM_001161630
KDM4DL
lysine (K)-specific demethylase 4D-like
chr19_-_9087438 0.807 NM_001005192
OR7G1
olfactory receptor, family 7, subfamily G, member 1
chr1_+_35507197 0.804 ZMYM4
zinc finger, MYM-type 4
chr6_+_163904564 0.803 QKI
quaking homolog, KH domain RNA binding (mouse)
chr1_-_148854503 0.793


chr17_+_50333021 0.793 NM_005486
TOM1L1
target of myb1 (chicken)-like 1
chr12_+_47810915 0.789


chr6_+_146097700 0.784 LOC100507557
hypothetical LOC100507557
chr7_-_112515068 0.777 NM_001146265
NM_018970
GPR85

G protein-coupled receptor 85

chr9_+_95886625 0.777 PTPDC1
protein tyrosine phosphatase domain containing 1
chr7_+_128367961 0.767 NM_001098627
IRF5
interferon regulatory factor 5
chr11_+_93394025 0.760 NM_001098672
HEPHL1
hephaestin-like 1
chr9_+_95886558 0.760 NM_152422
PTPDC1
protein tyrosine phosphatase domain containing 1
chr11_-_123772456 0.760 NM_001005467
OR8B3
olfactory receptor, family 8, subfamily B, member 3
chr12_-_49708279 0.759 NM_001174125
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr20_+_186376 0.759 NM_207469
DEFB132
defensin, beta 132
chr22_+_19248733 0.755 MED15
mediator complex subunit 15
chr14_+_87560646 0.742 LOC283587
hypothetical protein LOC283587
chr1_-_110752068 0.737 NM_006402
HBXIP
hepatitis B virus x interacting protein
chr12_-_54522881 0.731 NM_002429
MMP19
matrix metallopeptidase 19
chr6_+_31661934 0.729 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr1_+_149877955 0.728 SNX27
sorting nexin family member 27
chr1_+_182287388 0.724 NM_001127394
NM_052965
TSEN15

tRNA splicing endonuclease 15 homolog (S. cerevisiae)

chr12_-_55696542 0.720 NM_001178054
NM_013251
TAC3

tachykinin 3

chr1_-_160613203 0.720 NM_182581
C1orf111
chromosome 1 open reading frame 111
chr2_-_30883775 0.711 NM_144575
CAPN13
calpain 13
chr21_+_44729875 0.708


chr1_-_21373816 0.706 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr12_+_54672766 0.703 RAB5B
RAB5B, member RAS oncogene family
chr10_-_85991177 0.702 NM_015613
LRIT1
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
chr2_-_157890400 0.699 NM_020711
ERMN
ermin, ERM-like protein
chrX_+_56606686 0.699 NM_013444
UBQLN2
ubiquilin 2
chr1_+_101475149 0.696 S1PR1
sphingosine-1-phosphate receptor 1
chr1_-_159787004 0.696 NM_001127593
NM_001127595
NM_001127596
FCGR3A


Fc fragment of IgG, low affinity IIIa, receptor (CD16a)


chr14_-_20128228 0.694 NM_145250
RNASE11
ribonuclease, RNase A family, 11 (non-active)
chr12_+_28301399 0.692 NM_018318
CCDC91
coiled-coil domain containing 91
chr21_-_39737997 0.691 NM_152505
LCA5L
Leber congenital amaurosis 5-like
chr2_+_3605611 0.689 RPS7
ribosomal protein S7
chr7_-_112514990 0.688 GPR85
G protein-coupled receptor 85
chr3_-_57209319 0.684 NM_003865
HESX1
HESX homeobox 1
chr6_+_2990616 0.681 NM_001012983
FAM136BP
family with sequence similarity 136, member B, pseudogene
chr2_-_20115269 0.675 NM_014713
LAPTM4A
lysosomal protein transmembrane 4 alpha
chr7_-_112515035 0.671 GPR85
G protein-coupled receptor 85
chr1_+_76035154 0.671 NM_002440
MSH4
mutS homolog 4 (E. coli)
chr1_-_165754325 0.671 NM_000734
NM_198053
CD247

CD247 molecule

chr19_+_44662891 0.669 NM_001001563
TIMM50
translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
chr1_+_40977092 0.665 NFYC
nuclear transcription factor Y, gamma
chr11_+_34599227 0.664 EHF
ets homologous factor
chr5_-_74568458 0.663 NM_001164443
ANKRD31
ankyrin repeat domain 31
chr1_-_109201228 0.662 NM_152763
AKNAD1
AKNA domain containing 1
chr1_-_27871287 0.660 IFI6
interferon, alpha-inducible protein 6
chr9_-_74757735 0.660 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr17_-_8215577 0.657 NM_213597
KRBA2
KRAB-A domain containing 2
chr1_-_158883666 0.655 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr11_-_64484184 0.655 NM_001037225
C11orf85
chromosome 11 open reading frame 85
chr2_-_65013070 0.653 LOC400958
hypothetical LOC400958

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.59 4.78e-03 GO:0007600 sensory perception

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.69 2.53e-02 GO:0008289 lipid binding
12.07 2.99e-02 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity