Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 2.066


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
UBTFchr17_-_396544070.741.7e-03Click!
HMGB3chrX_+_149902415-0.441.0e-01Click!
HMGB2chr4_-_1744920290.293.0e-01Click!
HBP1chr7_+_1065966410.175.6e-01Click!
SSRP1chr11_-_56859900-0.136.3e-01Click!


Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_129496792 7.019 APLP2
amyloid beta (A4) precursor-like protein 2
chr3_-_116272911 5.643 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr6_-_111995213 5.090 NM_001164283
TRAF3IP2
TRAF3 interacting protein 2
chr4_-_101658094 4.958 NM_001159694
NM_016242
EMCN

endomucin

chrX_-_19598912 4.685 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr7_-_27186400 4.484 NM_153715
HOXA10
homeobox A10
chr4_+_141397889 4.318 NM_032547
SCOC
short coiled-coil protein
chr2_-_162808123 3.991 NM_004460
FAP
fibroblast activation protein, alpha
chr16_+_85169615 3.926 NM_005250
FOXL1
forkhead box L1
chr3_-_150533948 3.857 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr1_-_177106702 3.793 NM_004673
ANGPTL1
angiopoietin-like 1
chr11_-_85108030 3.727 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr2_-_56266408 3.688 LOC100129434
hypothetical LOC100129434
chr9_-_23816062 3.661 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr18_+_7936885 3.493 PTPRM
protein tyrosine phosphatase, receptor type, M
chr8_+_70567634 3.302 SULF1
sulfatase 1
chr9_+_18464090 3.298 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr8_+_70567581 3.277 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr8_-_93144039 3.242


chr11_+_57547928 3.239 NM_001005212
OR9Q1
olfactory receptor, family 9, subfamily Q, member 1
chr3_-_11585264 3.169 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr12_-_16649211 3.139 LMO3
LIM domain only 3 (rhombotin-like 2)
chr9_+_102380156 3.135 NM_001018116
MURC
muscle-related coiled-coil protein
chr2_-_72228427 3.032 NM_019885
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr7_+_134114912 3.000 CALD1
caldesmon 1
chr9_+_18464138 2.986 ADAMTSL1
ADAMTS-like 1
chr8_-_93144366 2.956 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_81544432 2.942 LPHN2
latrophilin 2
chr7_-_83662152 2.861 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr20_+_19818209 2.837 NM_018993
RIN2
Ras and Rab interactor 2
chr3_+_174598937 2.796 NM_014932
NLGN1
neuroligin 1
chr5_-_111119846 2.768 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr15_+_37330176 2.760 NM_207445
C15orf54
chromosome 15 open reading frame 54
chr11_-_85107569 2.750 NM_206929
SYTL2
synaptotagmin-like 2
chr9_+_676640 2.750


chr7_-_27153892 2.748 NM_024014
HOXA6
homeobox A6
chr6_+_21774624 2.738 FLJ22536
hypothetical locus LOC401237
chr3_+_148593911 2.721


chr3_-_188936941 2.717 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr7_+_134114957 2.676 CALD1
caldesmon 1
chr8_-_108579270 2.675 NM_001146
ANGPT1
angiopoietin 1
chr5_-_83052606 2.663 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chr10_-_118887801 2.644 NM_001112704
NM_199131
VAX1

ventral anterior homeobox 1

chr6_+_153060722 2.629 NM_025107
MYCT1
myc target 1
chr14_+_36196523 2.625 NM_006194
PAX9
paired box 9
chr3_+_173043832 2.569 NM_001164436
TMEM212
transmembrane protein 212
chr7_-_27108826 2.512 NM_006735
HOXA2
homeobox A2
chr2_-_128138435 2.510 NM_017980
LIMS2
LIM and senescent cell antigen-like domains 2
chr6_+_148705421 2.503 NM_015278
SASH1
SAM and SH3 domain containing 1
chr10_+_104525877 2.491 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr1_-_242073094 2.468 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chr16_+_65938753 2.445 NM_001161575
LRRC36
leucine rich repeat containing 36
chrX_+_135079461 2.409 NM_001167819
FHL1
four and a half LIM domains 1
chr6_-_56824672 2.403 DST
dystonin
chr12_-_10142779 2.355 NM_016511
CLEC1A
C-type lectin domain family 1, member A
chr3_+_182900081 2.332 SOX2OT
SOX2 overlapping transcript (non-protein coding)
chr2_+_108571336 2.317 NM_001193488
LIMS1
LIM and senescent cell antigen-like domains 1
chr5_-_38631263 2.294 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr15_+_45797977 2.294 NM_020858
NM_024966
NM_153616
NM_153617
NM_153618
NM_153619
SEMA6D





sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D





chr7_-_27149750 2.290 NM_019102
HOXA5
homeobox A5
chr13_-_32678142 2.276 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr9_+_27099138 2.248 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr16_+_1068781 2.244 NM_001053
SSTR5
somatostatin receptor 5
chr14_+_76298693 2.233 VASH1
vasohibin 1
chr15_-_53996597 2.213 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr21_-_27261276 2.186 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr8_-_6407882 2.165 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr10_-_116434364 2.159 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr3_-_115825742 2.148 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr5_-_44424423 2.135 NM_004465
FGF10
fibroblast growth factor 10
chrX_+_15428820 2.135 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr6_-_94185780 2.133 NM_004440
EPHA7
EPH receptor A7
chr6_-_134540666 2.127 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr8_-_18710575 2.125 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr20_-_45418818 2.123 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr13_+_23742846 2.114 SPATA13
spermatogenesis associated 13
chr7_-_11838260 2.112 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr5_+_170668892 2.108 NM_021025
TLX3
T-cell leukemia homeobox 3
chr17_+_72795567 2.044 NM_001113492
SEPT9
septin 9
chr6_-_139654807 2.013 NM_153235
TXLNB
taxilin beta
chr6_-_56824371 2.008 DST
dystonin
chr1_-_152431175 2.007 NM_152263
TPM3
tropomyosin 3
chr15_-_68781662 2.000 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr6_+_31190505 1.965 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr9_-_16717887 1.952 BNC2
basonuclin 2
chr13_-_35327798 1.943 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr18_+_71051713 1.935 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr18_-_29412148 1.931


chr5_-_39400319 1.911 NM_001737
C9
complement component 9
chr3_+_152970904 1.881 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr17_+_72380323 1.869 NM_198955
MGAT5B
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr17_-_46479127 1.856 SPAG9
sperm associated antigen 9
chr12_-_6103945 1.846 NM_000552
VWF
von Willebrand factor
chrX_-_33267646 1.841 NM_000109
DMD
dystrophin
chr5_-_158567411 1.839 NM_144726
RNF145
ring finger protein 145
chr1_+_22107137 1.834 RPL21
ribosomal protein L21
chr3_-_69254226 1.834 NM_198271
LMOD3
leiomodin 3 (fetal)
chr14_-_88953059 1.823 NM_005197
FOXN3
forkhead box N3
chr14_-_91483325 1.822 FBLN5
fibulin 5
chr10_+_123913094 1.810 NM_006997
NM_206860
TACC2

transforming, acidic coiled-coil containing protein 2

chr8_-_93099040 1.808 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_82557956 1.800 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr7_+_102340579 1.795 NM_001031692
NM_005824
LRRC17

leucine rich repeat containing 17

chr13_+_99431417 1.779


chr6_-_138935359 1.778 NM_020464
NHSL1
NHS-like 1
chrX_+_135079120 1.773 NM_001159704
FHL1
four and a half LIM domains 1
chr1_+_15145001 1.769 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr11_+_112337199 1.766 NM_000615
NM_001076682
NM_181351
NCAM1


neural cell adhesion molecule 1


chr9_-_15240113 1.762 NM_001168342
TTC39B
tetratricopeptide repeat domain 39B
chr12_+_32546243 1.752 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr2_+_33213111 1.738 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chrX_-_50573759 1.727 NM_020717
SHROOM4
shroom family member 4
chr5_-_125956996 1.726 ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr4_-_186814852 1.713 SORBS2
sorbin and SH3 domain containing 2
chr9_-_8723893 1.712 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr7_-_27125738 1.696 NM_030661
HOXA3
homeobox A3
chr3_-_71376919 1.685 FOXP1
forkhead box P1
chr21_-_31853160 1.677 NM_003253
TIAM1
T-cell lymphoma invasion and metastasis 1
chr20_+_11846536 1.666 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr17_-_1359745 1.658 INPP5K
inositol polyphosphate-5-phosphatase K
chr4_-_20594645 1.657 KCNIP4
Kv channel interacting protein 4
chr7_+_134114701 1.655 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr17_-_71017509 1.650 NM_001142643
CASKIN2
CASK interacting protein 2
chr8_+_40130143 1.649 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr9_+_117955890 1.647 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr12_+_13240983 1.642 EMP1
epithelial membrane protein 1
chr5_+_15553288 1.637 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr20_+_31613800 1.609 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr13_-_98428244 1.607 NM_001130048
NM_001130050
DOCK9

dedicator of cytokinesis 9

chr7_+_45894480 1.588 NM_000596
IGFBP1
insulin-like growth factor binding protein 1
chr12_+_83954229 1.586 NM_001079910
NM_032165
LRRIQ1

leucine-rich repeats and IQ motif containing 1

chrX_+_152684150 1.585 PLXNB3
plexin B3
chr12_-_44644216 1.584


chrX_+_77889861 1.572 NM_005296
LPAR4
lysophosphatidic acid receptor 4
chr4_-_73653331 1.572 NM_014243
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr12_+_13240987 1.563 EMP1
epithelial membrane protein 1
chr17_+_72376022 1.549 NM_144677
MGAT5B
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr12_-_120725210 1.545 LOC338799
hypothetical LOC338799
chr10_+_80672842 1.539 ZMIZ1
zinc finger, MIZ-type containing 1
chr4_+_146820805 1.538 NM_001080531
C4orf51
chromosome 4 open reading frame 51
chr18_+_29412538 1.538 NM_030632
ASXL3
additional sex combs like 3 (Drosophila)
chr2_-_213111525 1.529 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr5_-_16795336 1.516 MYO10
myosin X
chr2_-_73170290 1.507 RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr7_-_41709191 1.506 NM_002192
INHBA
inhibin, beta A
chr21_-_38792173 1.492 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr2_-_183095308 1.490 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr4_-_152366970 1.487 NM_001009555
NM_001128923
SH3D19

SH3 domain containing 19

chr13_-_32658215 1.482 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chr5_-_147266257 1.473 NM_206966
C5orf46
chromosome 5 open reading frame 46
chr6_-_56615544 1.462 NM_001723
NM_015548
DST

dystonin

chr1_+_176577228 1.459 NM_004841
RASAL2
RAS protein activator like 2
chr9_-_4289915 1.457 GLIS3
GLIS family zinc finger 3
chr5_-_83715947 1.437 EDIL3
EGF-like repeats and discoidin I-like domains 3
chr7_+_134226690 1.437 NM_033139
NM_033140
CALD1

caldesmon 1

chrX_-_62891066 1.425 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr1_+_161305188 1.425 NM_005613
RGS4
regulator of G-protein signaling 4
chr2_+_36777336 1.423 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
VIT




vitrin




chr10_-_32707549 1.414 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr6_-_42218692 1.412 NM_001164446
C6orf132
chromosome 6 open reading frame 132
chr14_+_57964462 1.409 NM_014749
KIAA0586
KIAA0586
chr10_-_103864579 1.408 LDB1
LIM domain binding 1
chr2_-_133144094 1.403 LYPD1
LY6/PLAUR domain containing 1
chr12_-_83954185 1.401 NM_001100917
TSPAN19
tetraspanin 19
chr4_-_152368492 1.399 SH3D19
SH3 domain containing 19
chr4_+_119174947 1.392 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr5_+_149960820 1.391 NM_001166208
SYNPO
synaptopodin
chr9_-_129557373 1.390 NM_001142534
NM_001142533
SH2D3C

SH2 domain containing 3C

chr1_-_68470585 1.388 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr11_+_20001130 1.386 NM_001111019
NAV2
neuron navigator 2
chr5_-_83716346 1.386 NM_005711
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr9_+_35896188 1.385 NM_001039792
HRCT1
histidine rich carboxyl terminus 1
chr4_+_87070449 1.383 NM_031305
ARHGAP24
Rho GTPase activating protein 24
chr9_+_130719034 1.381 LRRC8A
leucine rich repeat containing 8 family, member A
chr2_-_213723298 1.370 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr14_+_62740878 1.367 NM_020663
RHOJ
ras homolog gene family, member J
chr7_+_134226727 1.354 CALD1
caldesmon 1
chr5_-_175896829 1.352 NM_014901
RNF44
ring finger protein 44
chr2_-_188021117 1.349 NM_005795
CALCRL
calcitonin receptor-like
chr1_+_226404037 1.347 NM_020435
GJC2
gap junction protein, gamma 2, 47kDa
chr8_+_32623792 1.345 NM_013959
NRG1
neuregulin 1
chr10_+_101532450 1.341 NM_000392
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr9_-_72673753 1.333 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chrX_-_31436335 1.328 NM_004014
DMD
dystrophin
chr16_+_54072969 1.319 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr10_-_123346148 1.311 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr6_-_74284522 1.307 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr3_-_49372584 1.306 RHOA
ras homolog gene family, member A
chr9_-_116190038 1.302 AKNA
AT-hook transcription factor
chr2_-_134042500 1.302 NM_207363
NM_207481
NCKAP5

NCK-associated protein 5

chr17_-_36346240 1.302 KRT23
keratin 23 (histone deacetylase inducible)
chr11_+_20000938 1.301 NAV2
neuron navigator 2
chr2_-_133145539 1.293 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr11_-_121492010 1.288 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr9_+_124835608 1.283 RABGAP1
GPR21
RAB GTPase activating protein 1
G protein-coupled receptor 21
chr4_+_160408447 1.281 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr3_-_48576204 1.268 NM_033199
UCN2
urocortin 2
chr4_-_138673078 1.267 NM_019035
PCDH18
protocadherin 18
chr11_+_101488380 1.263 NM_001195045
YAP1
Yes-associated protein 1
chr6_-_89984214 1.256 NM_002042
GABRR1
gamma-aminobutyric acid (GABA) receptor, rho 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.31 1.99e-18 GO:0032501 multicellular organismal process
1.43 7.39e-18 GO:0048856 anatomical structure development
1.44 8.54e-17 GO:0048731 system development
1.37 1.07e-16 GO:0032502 developmental process
1.39 2.19e-16 GO:0007275 multicellular organismal development
1.62 9.29e-15 GO:0007399 nervous system development
1.54 3.76e-11 GO:0009653 anatomical structure morphogenesis
2.85 1.96e-09 GO:0007156 homophilic cell adhesion
1.41 8.34e-09 GO:0030154 cell differentiation
1.40 9.51e-09 GO:0048869 cellular developmental process
1.70 1.67e-08 GO:0007155 cell adhesion
1.70 1.67e-08 GO:0022610 biological adhesion
1.67 8.67e-07 GO:0030182 neuron differentiation
1.59 1.18e-06 GO:0048699 generation of neurons
1.57 1.23e-06 GO:0022008 neurogenesis
1.99 5.26e-06 GO:0016337 cell-cell adhesion
2.97 1.25e-05 GO:0048706 embryonic skeletal system development
1.35 2.35e-05 GO:0048513 organ development
1.63 3.61e-05 GO:0032989 cellular component morphogenesis
1.71 4.17e-05 GO:0000904 cell morphogenesis involved in differentiation
1.64 5.75e-05 GO:0000902 cell morphogenesis
1.50 8.04e-05 GO:0048468 cell development
1.62 1.34e-04 GO:0009887 organ morphogenesis
1.15 2.40e-04 GO:0050896 response to stimulus
2.51 2.43e-04 GO:0048736 appendage development
2.51 2.43e-04 GO:0060173 limb development
2.54 2.72e-04 GO:0035107 appendage morphogenesis
2.54 2.72e-04 GO:0035108 limb morphogenesis
1.68 3.32e-04 GO:0072358 cardiovascular system development
1.68 3.32e-04 GO:0072359 circulatory system development
1.84 3.68e-04 GO:0001501 skeletal system development
1.71 5.51e-04 GO:0007409 axonogenesis
1.45 7.47e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.69 7.82e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.68 9.24e-04 GO:0048812 neuron projection morphogenesis
1.63 1.22e-03 GO:0031175 neuron projection development
1.47 1.36e-03 GO:0040011 locomotion
1.58 1.52e-03 GO:0048666 neuron development
1.55 2.07e-03 GO:0045893 positive regulation of transcription, DNA-dependent
2.23 3.54e-03 GO:0048705 skeletal system morphogenesis
1.25 3.78e-03 GO:0048519 negative regulation of biological process
1.88 4.69e-03 GO:0003002 regionalization
1.61 4.79e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.49 5.46e-03 GO:0009790 embryo development
1.50 5.92e-03 GO:0010628 positive regulation of gene expression
1.47 6.97e-03 GO:2000026 regulation of multicellular organismal development
2.47 9.72e-03 GO:0051271 negative regulation of cellular component movement
1.18 9.75e-03 GO:0023052 signaling
1.57 1.06e-02 GO:0048858 cell projection morphogenesis
4.88 1.24e-02 GO:0060441 epithelial tube branching involved in lung morphogenesis
1.69 1.26e-02 GO:0007389 pattern specification process
2.06 1.56e-02 GO:0045165 cell fate commitment
1.56 1.57e-02 GO:0032990 cell part morphogenesis
1.34 1.63e-02 GO:0051239 regulation of multicellular organismal process
1.65 1.70e-02 GO:0048598 embryonic morphogenesis
1.19 1.71e-02 GO:0016043 cellular component organization
1.55 1.72e-02 GO:0007417 central nervous system development
1.63 1.76e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.10 1.79e-02 GO:0065007 biological regulation
2.47 2.14e-02 GO:0030336 negative regulation of cell migration
2.47 2.14e-02 GO:2000146 negative regulation of cell motility
1.25 2.17e-02 GO:0048523 negative regulation of cellular process
2.00 2.24e-02 GO:0009952 anterior/posterior pattern formation
2.01 2.26e-02 GO:0048562 embryonic organ morphogenesis
1.47 2.72e-02 GO:0051254 positive regulation of RNA metabolic process
1.54 2.78e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.72 3.18e-02 GO:0001944 vasculature development
1.67 3.18e-02 GO:0007411 axon guidance
1.11 3.27e-02 GO:0050789 regulation of biological process
2.30 4.42e-02 GO:0030326 embryonic limb morphogenesis
2.30 4.42e-02 GO:0035113 embryonic appendage morphogenesis
2.65 4.87e-02 GO:0048704 embryonic skeletal system morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.71 8.57e-08 GO:0030054 cell junction
1.22 2.46e-07 GO:0071944 cell periphery
1.23 3.15e-07 GO:0005886 plasma membrane
1.94 7.99e-07 GO:0005578 proteinaceous extracellular matrix
1.80 6.67e-06 GO:0031012 extracellular matrix
2.53 8.06e-06 GO:0044420 extracellular matrix part
2.30 7.57e-04 GO:0030055 cell-substrate junction
1.85 8.64e-04 GO:0016323 basolateral plasma membrane
2.06 1.27e-03 GO:0005912 adherens junction
2.00 1.50e-03 GO:0070161 anchoring junction
2.29 2.44e-03 GO:0005925 focal adhesion
1.37 2.72e-03 GO:0044421 extracellular region part
1.24 3.97e-03 GO:0044459 plasma membrane part
1.59 4.61e-03 GO:0045202 synapse
2.18 7.46e-03 GO:0005924 cell-substrate adherens junction
2.41 1.68e-02 GO:0005604 basement membrane
7.32 2.37e-02 GO:0071437 invadopodium
1.75 4.00e-02 GO:0005911 cell-cell junction
2.18 4.96e-02 GO:0030027 lamellipodium

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.51 1.07e-06 GO:0030528 transcription regulator activity
1.48 8.67e-06 GO:0001071 nucleic acid binding transcription factor activity
1.48 8.67e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.58 1.21e-05 GO:0043565 sequence-specific DNA binding
1.55 8.65e-05 GO:0005509 calcium ion binding
1.77 3.42e-04 GO:0016563 transcription activator activity
1.64 1.12e-02 GO:0003779 actin binding
1.47 2.34e-02 GO:0008092 cytoskeletal protein binding
1.10 3.23e-02 GO:0005515 protein binding
2.17 4.78e-02 GO:0005088 Ras guanyl-nucleotide exchange factor activity