Motif ID: SPZ1.p2

Z-value: 1.269


Transcription factors associated with SPZ1.p2:

Gene SymbolEntrez IDGene Name
SPZ1 84654 spermatogenic leucine zipper 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPZ1chr5_+_796515450.273.2e-01Click!


Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_52980914 0.866 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr1_+_199130571 0.854 NM_001142569
C1orf106
chromosome 1 open reading frame 106
chr17_-_36469869 0.797 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr19_+_45973139 0.745 NM_006533
MIA
melanoma inhibitory activity
chr3_+_214668 0.738


chr16_+_29819647 0.724 NM_181718
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr10_-_105411339 0.716 SH3PXD2A
SH3 and PX domains 2A
chr17_-_74231266 0.673 CYTH1
cytohesin 1
chr17_-_24973940 0.662 CORO6
coronin 6
chr17_-_36475652 0.643 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr11_+_12987455 0.634 NM_001080521
RASSF10
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr6_-_41230003 0.608 NM_178174
TREML1
triggering receptor expressed on myeloid cells-like 1
chr1_-_151855413 0.608 NM_020672
S100A14
S100 calcium binding protein A14
chr6_-_119712596 0.590 NM_005907
MAN1A1
mannosidase, alpha, class 1A, member 1
chr3_-_62835601 0.584


chr17_-_77824849 0.580 NM_001893
NM_139062
CSNK1D

casein kinase 1, delta

chr11_-_110755366 0.565 NM_006235
POU2AF1
POU class 2 associating factor 1
chr12_-_52980984 0.565 NM_001136023
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr16_-_66535457 0.560 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr17_+_33761234 0.558 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr1_-_150070849 0.557 NM_005060
RORC
RAR-related orphan receptor C
chr14_-_22974707 0.550 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr17_+_45405128 0.535 NM_001934
DLX4
distal-less homeobox 4
chr2_-_219633481 0.534 NM_002181
IHH
Indian hedgehog
chr16_+_2461500 0.534 NM_006181
NTN3
netrin 3
chr18_-_26935883 0.531 NM_004949
NM_024422
DSC2

desmocollin 2

chr1_-_32574185 0.520 NM_023009
MARCKSL1
MARCKS-like 1
chr1_+_27541086 0.514 SYTL1
synaptotagmin-like 1
chr6_+_37245860 0.510 NM_002648
PIM1
pim-1 oncogene
chr11_-_57171554 0.509 YPEL4
yippee-like 4 (Drosophila)
chr21_+_44844924 0.492 NM_198689
KRTAP10-7
keratin associated protein 10-7
chr17_+_35075124 0.487 NM_003673
TCAP
titin-cap (telethonin)
chr17_-_74231240 0.486 CYTH1
cytohesin 1
chr14_-_22596522 0.478 NM_022478
NM_144985
CDH24

cadherin 24, type 2

chr17_-_73640082 0.477 NM_007267
TMC6
transmembrane channel-like 6
chr16_-_28425632 0.475 NM_145659
IL27
interleukin 27
chr11_-_116168316 0.464 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr17_+_45965044 0.461 NM_017957
EPN3
epsin 3
chr10_+_47867667 0.452 NM_001137556
NM_001137549
NM_001137548
FAM25B
FAM25G
FAM25C
family with sequence similarity 25, member B
family with sequence similarity 25, member G
family with sequence similarity 25, member C
chr17_-_36456949 0.451 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr10_-_23673777 0.449 NM_153714
C10orf67
chromosome 10 open reading frame 67
chr1_-_11909042 0.449 NM_138346
KIAA2013
KIAA2013
chr10_+_82106537 0.440 NM_032372
DYDC2
DPY30 domain containing 2
chr17_-_37586716 0.438 NM_012285
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr11_-_35503720 0.435 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr12_+_48784057 0.430 NM_005276
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr1_-_150079656 0.429 NM_001136003
C2CD4D
C2 calcium-dependent domain containing 4D
chr2_-_85490984 0.425 CAPG
capping protein (actin filament), gelsolin-like
chr16_+_56211150 0.424 GPR56
G protein-coupled receptor 56
chr8_+_142471290 0.424


chr11_-_45643711 0.422 NM_003654
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr3_+_187840842 0.421 NM_014375
FETUB
fetuin B
chr5_-_142046175 0.414 NM_033136
FGF1
fibroblast growth factor 1 (acidic)
chr1_+_154478574 0.414 NM_199173
BGLAP
bone gamma-carboxyglutamate (gla) protein
chr15_-_71448194 0.410 HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr17_+_72795567 0.409 NM_001113492
SEPT9
septin 9
chr16_+_56211410 0.406 NM_001145770
NM_005682
GPR56

G protein-coupled receptor 56

chr10_-_46601687 0.405 NM_001137556
NM_001137549
NM_001137548
FAM25B
FAM25G
FAM25C
family with sequence similarity 25, member B
family with sequence similarity 25, member G
family with sequence similarity 25, member C
chr10_-_71002998 0.405 NM_020999
NEUROG3
neurogenin 3
chr2_+_219532590 0.405 NM_003936
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr20_-_22514092 0.402 NM_153675
FOXA2
forkhead box A2
chr5_+_129268352 0.402 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr15_-_71448657 0.399 NM_005477
HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr1_-_43168247 0.398 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr9_+_129951552 0.396 NM_005564
LCN2
lipocalin 2
chr6_-_116488458 0.396 NM_002031
FRK
fyn-related kinase
chr16_+_65579988 0.395 NM_173815
CES4A
carboxylesterase 4A
chr12_-_24606616 0.394 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr8_-_144887876 0.394 NM_198488
FAM83H
family with sequence similarity 83, member H
chr22_+_38720881 0.393 NM_138435
FAM83F
family with sequence similarity 83, member F
chr15_-_19221463 0.391


chr3_-_13436802 0.388 NM_024923
NUP210
nucleoporin 210kDa
chr6_-_31853027 0.385 NM_025258
C6orf27
chromosome 6 open reading frame 27
chr5_+_75414994 0.384 NM_014979
SV2C
synaptic vesicle glycoprotein 2C
chr1_-_39929654 0.383 NM_016257
HPCAL4
hippocalcin like 4
chr2_-_85490997 0.382 NM_001747
CAPG
capping protein (actin filament), gelsolin-like
chr20_+_31334601 0.381 NM_033197
C20orf114
chromosome 20 open reading frame 114
chr12_+_52665196 0.380 NM_017409
HOXC10
homeobox C10
chr12_+_39372456 0.379 NM_001843
NM_175038
CNTN1

contactin 1

chr12_-_48017223 0.379 NM_001008223
C1QL4
complement component 1, q subcomponent-like 4
chr17_-_36528113 0.379 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr17_-_37144408 0.378 NM_001079870
NM_001079871
NM_177977
HAP1


huntingtin-associated protein 1


chr17_+_35853177 0.378 NM_001552
IGFBP4
insulin-like growth factor binding protein 4
chr14_+_89597860 0.377 NM_022054
KCNK13
potassium channel, subfamily K, member 13
chr16_+_12902955 0.370 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr17_-_19560470 0.370 NM_001099646
NM_152908
SLC47A2

solute carrier family 47, member 2

chr16_-_29929801 0.369 NM_003586
DOC2A
double C2-like domains, alpha
chr16_-_60627536 0.369 NM_001796
CDH8
cadherin 8, type 2
chr5_+_5193442 0.368 NM_139056
ADAMTS16
ADAM metallopeptidase with thrombospondin type 1 motif, 16
chr22_-_39964001 0.364 CHADL
chondroadherin-like
chr2_+_159360074 0.364 NM_001017920
DAPL1
death associated protein-like 1
chr20_+_20296744 0.363 NM_002196
INSM1
insulinoma-associated 1
chr15_-_73792234 0.363 NM_001897
CSPG4
chondroitin sulfate proteoglycan 4
chr12_+_47658502 0.360 NM_005430
WNT1
wingless-type MMTV integration site family, member 1
chr19_-_6671585 0.359 NM_000064
C3
complement component 3
chr16_+_22432344 0.359 NM_001135865
LOC100132247
NPIPL3
nuclear pore complex interacting protein related gene
nuclear pore complex interacting protein-like 3
chr20_+_60558369 0.358 C20orf166
chromosome 20 open reading frame 166
chrX_-_106033202 0.357 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr11_-_35397090 0.357 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr17_+_70431964 0.352 NM_178160
OTOP2
otopetrin 2
chr2_+_232951487 0.349 NM_001632
ALPP
alkaline phosphatase, placental
chr17_-_40858775 0.347 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr11_+_19691397 0.346 NM_145117
NM_182964
NAV2

neuron navigator 2

chrX_+_105856531 0.346 NM_194463
RNF128
ring finger protein 128
chr17_-_40344203 0.345 GFAP
glial fibrillary acidic protein
chr19_+_12810258 0.344 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr11_+_67007155 0.343 AIP
aryl hydrocarbon receptor interacting protein
chr20_-_30636535 0.342 LOC284804
hypothetical protein LOC284804
chr13_+_40929525 0.341 NM_014059
C13orf15
chromosome 13 open reading frame 15
chr14_-_64416307 0.340 SPTB
spectrin, beta, erythrocytic
chr17_-_35017650 0.340 NEUROD2
neurogenic differentiation 2
chr9_-_106705867 0.338 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr1_+_14797764 0.338 NM_015209
NM_201628
KAZN

kazrin, periplakin interacting protein

chr17_-_45901173 0.337 NM_001267
CHAD
chondroadherin
chr6_-_30151526 0.334 NM_170769
NM_025236
RNF39

ring finger protein 39

chr2_-_36384 0.333 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr15_-_81113676 0.333 NM_030594
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr17_+_41217435 0.332 CRHR1
corticotropin releasing hormone receptor 1
chr22_-_44751671 0.332 NM_058238
WNT7B
wingless-type MMTV integration site family, member 7B
chr15_+_38437703 0.331 NM_033510
DISP2
dispatched homolog 2 (Drosophila)
chr14_+_22581215 0.330 NM_001099780
PSMB11
proteasome (prosome, macropain) subunit, beta type, 11
chr16_+_29373365 0.330 NM_001014999
NM_001015000
NM_024044
NM_178044
SLX1A-SULT1A3
SLX1A

SLX1B

SLX1A-SULT1A3 read-through transcript
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)

SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)

chr10_-_118419459 0.330 NM_144661
C10orf82
chromosome 10 open reading frame 82
chr1_-_41722883 0.330 NM_001956
EDN2
endothelin 2
chr2_-_127580975 0.329 NM_004305
NM_139343
NM_139344
NM_139345
NM_139346
NM_139347
NM_139348
NM_139349
NM_139350
NM_139351
BIN1









bridging integrator 1









chr17_+_71582486 0.329 NM_003857
GALR2
galanin receptor 2
chr11_+_67007080 0.329 NM_003977
AIP
aryl hydrocarbon receptor interacting protein
chr20_-_30535045 0.327 C20orf112
chromosome 20 open reading frame 112
chr19_+_53747233 0.326 NM_177973
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr5_-_134899537 0.325 NM_006161
NEUROG1
neurogenin 1
chr6_-_31789824 0.325


chr3_-_13089547 0.324 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr1_+_151917674 0.320 NM_000906
NPR1
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr7_-_156495985 0.319 NM_005515
MNX1
motor neuron and pancreas homeobox 1
chr1_+_176748834 0.318 NM_001170722
NM_001170723
NM_001170724
NM_032126
C1orf49



chromosome 1 open reading frame 49



chr16_-_66535923 0.317 SLC12A4
solute carrier family 12 (potassium/chloride transporters), member 4
chr21_+_44818033 0.317 NM_198687
KRTAP10-4
keratin associated protein 10-4
chr16_+_658081 0.316 NM_138769
RHOT2
ras homolog gene family, member T2
chr14_-_24588916 0.315 NM_014178
STXBP6
syntaxin binding protein 6 (amisyn)
chr6_-_109882116 0.314 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr9_+_138863673 0.311 PHPT1
phosphohistidine phosphatase 1
chr1_+_3378030 0.309 ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr22_-_49063088 0.309 PLXNB2
plexin B2
chr10_-_105410840 0.309


chr13_+_27264779 0.308 NM_145657
GSX1
GS homeobox 1
chr17_+_45993338 0.307 NM_018896
NM_198376
NM_198377
NM_198378
NM_198379
NM_198380
NM_198382
NM_198383
NM_198384
NM_198385
NM_198386
NM_198387
NM_198388
NM_198396
NM_198397
CACNA1G














calcium channel, voltage-dependent, T type, alpha 1G subunit














chr9_-_121171400 0.307 NM_014618
DBC1
deleted in bladder cancer 1
chr12_+_55018925 0.307 NM_016584
IL23A
interleukin 23, alpha subunit p19
chr20_-_34707971 0.306 NM_032214
NM_175077
SLA2

Src-like-adaptor 2

chr18_-_26996742 0.306 NM_004948
NM_024421
DSC1

desmocollin 1

chr18_-_55091596 0.304 NM_013435
RAX
retina and anterior neural fold homeobox
chr2_-_231498184 0.304 NM_005683
GPR55
G protein-coupled receptor 55
chr8_+_35212505 0.304 NM_080872
UNC5D
unc-5 homolog D (C. elegans)
chr3_+_46898673 0.304 NM_001184744
PTH1R
parathyroid hormone 1 receptor
chr8_-_22145462 0.304 PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr22_-_43040063 0.303 NM_001099294
KIAA1644
KIAA1644
chr3_+_125786195 0.302 NM_007064
KALRN
kalirin, RhoGEF kinase
chr1_-_1525309 0.302 LOC643988
hypothetical LOC643988
chr16_+_2954217 0.301 NM_024507
NM_172229
KREMEN2

kringle containing transmembrane protein 2

chr7_-_102070473 0.297 NM_001114403
UPK3BL
POLR2J2
uroplakin 3B-like
polymerase (RNA) II (DNA directed) polypeptide J2
chr2_+_241213334 0.296 NM_005301
GPR35
G protein-coupled receptor 35
chr1_+_46413335 0.295 NM_005727
TSPAN1
tetraspanin 1
chr10_-_71753684 0.293 LRRC20
leucine rich repeat containing 20
chr20_-_33343617 0.293 NM_178468
FAM83C
family with sequence similarity 83, member C
chr3_-_187562470 0.292 NM_001080744
NM_001080745
NM_001346
DGKG


diacylglycerol kinase, gamma 90kDa


chr15_-_73792150 0.292 CSPG4
chondroitin sulfate proteoglycan 4
chr4_-_120768563 0.289 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr16_-_87378872 0.285 NM_001142864
FAM38A
family with sequence similarity 38, member A
chr10_-_79298876 0.283 DLG5
discs, large homolog 5 (Drosophila)
chr1_+_15935395 0.282 NM_207348
SLC25A34
solute carrier family 25, member 34
chr1_+_27541049 0.281 NM_001193308
NM_032872
SYTL1

synaptotagmin-like 1

chr11_+_27019084 0.280 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr16_-_4778317 0.279 NM_001154458
NM_144605
SEPT12

septin 12

chr21_+_26029542 0.279 GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr17_-_40344322 0.277


chr17_-_35017691 0.277 NM_006160
NEUROD2
neurogenic differentiation 2
chr8_+_65656164 0.277 BHLHE22
basic helix-loop-helix family, member e22
chr13_-_71338558 0.276 DACH1
dachshund homolog 1 (Drosophila)
chr4_+_995395 0.276 FGFRL1
fibroblast growth factor receptor-like 1
chr11_-_57039721 0.276 NM_003627
SLC43A1
solute carrier family 43, member 1
chr9_-_106705780 0.275 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr15_-_81412354 0.275 NM_004839
NM_199330
NM_199331
NM_199332
HOMER2



homer homolog 2 (Drosophila)



chr1_+_205137410 0.272 NM_001185156
NM_001185157
NM_001185158
NM_006850
IL24



interleukin 24



chr17_+_4348877 0.271 NM_001124758
SPNS2
spinster homolog 2 (Drosophila)
chr6_-_169392771 0.271


chr1_+_13782838 0.268 NM_006474
NM_198389
PDPN

podoplanin

chr5_-_111782637 0.267 NM_022140
EPB41L4A
erythrocyte membrane protein band 4.1 like 4A
chr15_-_81037554 0.267 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr5_-_92942680 0.267 FLJ42709
hypothetical LOC441094
chr2_+_242400702 0.267 NM_001167599
NM_001167602
NM_080741
NEU4


sialidase 4


chr5_+_79021401 0.267 NM_153610
CMYA5
cardiomyopathy associated 5
chr9_+_139241838 0.265 NM_001190228
LOC643596
hypothetical LOC643596
chr17_-_37034288 0.264 NM_000422
KRT17
keratin 17
chr16_+_65765256 0.264 NM_003946
NM_001185057
NOL3

nucleolar protein 3 (apoptosis repressor with CARD domain)

chr17_-_74432671 0.264 TIMP2
TIMP metallopeptidase inhibitor 2
chr15_+_97462675 0.263 NM_015286
NM_145728
SYNM

synemin, intermediate filament protein

chr14_+_20537253 0.263 NM_014579
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr18_-_22383066 0.263 NM_001136205
KCTD1
potassium channel tetramerisation domain containing 1
chr20_+_773283 0.262 NM_031424
FAM110A
family with sequence similarity 110, member A
chr1_+_203064397 0.262 NM_001005388
NM_001005389
NM_001160332
NM_001160333
NM_015090
NFASC




neurofascin





Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.27 7.15e-16 GO:0023052 signaling
1.45 1.12e-14 GO:0007399 nervous system development
1.15 4.23e-13 GO:0050789 regulation of biological process
1.16 5.38e-13 GO:0050794 regulation of cellular process
1.14 6.36e-13 GO:0065007 biological regulation
1.25 3.44e-12 GO:0007165 signal transduction
1.55 8.20e-12 GO:0048699 generation of neurons
1.24 3.01e-11 GO:0007275 multicellular organismal development
1.51 5.36e-11 GO:0022008 neurogenesis
1.27 6.49e-11 GO:0048731 system development
1.32 1.00e-10 GO:0030154 cell differentiation
1.57 4.71e-10 GO:0030182 neuron differentiation
1.38 5.80e-10 GO:0009653 anatomical structure morphogenesis
1.31 8.76e-10 GO:0048869 cellular developmental process
1.21 1.00e-09 GO:0032502 developmental process
1.65 4.12e-09 GO:0000904 cell morphogenesis involved in differentiation
1.23 8.17e-09 GO:0048856 anatomical structure development
1.46 1.32e-08 GO:0048468 cell development
1.16 1.59e-08 GO:0032501 multicellular organismal process
1.56 2.03e-08 GO:0032989 cellular component morphogenesis
1.65 1.02e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.65 1.04e-07 GO:0048812 neuron projection morphogenesis
1.66 2.04e-07 GO:0007409 axonogenesis
1.56 2.26e-07 GO:0048666 neuron development
1.54 3.91e-07 GO:0000902 cell morphogenesis
1.58 6.33e-07 GO:0048858 cell projection morphogenesis
1.57 1.33e-06 GO:0032990 cell part morphogenesis
1.57 1.67e-06 GO:0031175 neuron projection development
1.17 2.43e-06 GO:0051716 cellular response to stimulus
1.28 3.62e-06 GO:0007166 cell surface receptor linked signaling pathway
1.07 4.29e-06 GO:0009987 cellular process
1.21 1.43e-05 GO:0048518 positive regulation of biological process
1.37 2.06e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.28 2.09e-05 GO:0023051 regulation of signaling
1.26 2.11e-05 GO:0048583 regulation of response to stimulus
1.22 4.21e-05 GO:0048519 negative regulation of biological process
1.12 5.85e-05 GO:0050896 response to stimulus
1.21 8.33e-05 GO:0048522 positive regulation of cellular process
1.30 1.04e-04 GO:0051239 regulation of multicellular organismal process
1.93 1.46e-04 GO:0045165 cell fate commitment
1.44 1.52e-04 GO:0030030 cell projection organization
1.40 1.69e-04 GO:0007267 cell-cell signaling
1.34 2.37e-04 GO:0007154 cell communication
1.46 4.77e-04 GO:0051253 negative regulation of RNA metabolic process
1.32 5.43e-04 GO:0010646 regulation of cell communication
1.21 6.96e-04 GO:0048523 negative regulation of cellular process
1.58 7.35e-04 GO:0007411 axon guidance
1.45 9.64e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.39 9.86e-04 GO:0009890 negative regulation of biosynthetic process
1.42 9.96e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.54 1.04e-03 GO:0048598 embryonic morphogenesis
1.42 1.45e-03 GO:0009887 organ morphogenesis
1.36 1.50e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.35 1.65e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.38 1.79e-03 GO:0009790 embryo development
1.26 1.84e-03 GO:0009966 regulation of signal transduction
1.38 2.09e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.74 2.18e-03 GO:0048732 gland development
1.50 2.40e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.21 2.46e-03 GO:2000027 regulation of organ morphogenesis
1.38 2.82e-03 GO:0051254 positive regulation of RNA metabolic process
1.40 2.88e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33 3.11e-03 GO:0006351 transcription, DNA-dependent
1.40 3.12e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.47 3.35e-03 GO:0032583 regulation of gene-specific transcription
1.38 3.67e-03 GO:0010628 positive regulation of gene expression
1.59 4.01e-03 GO:0007423 sensory organ development
1.38 4.10e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.15 4.22e-03 GO:0031323 regulation of cellular metabolic process
1.39 4.44e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.53 4.57e-03 GO:0044057 regulation of system process
1.35 4.63e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21 4.80e-03 GO:0048513 organ development
1.27 5.37e-03 GO:0031325 positive regulation of cellular metabolic process
1.32 6.70e-03 GO:0009891 positive regulation of biosynthetic process
1.51 6.75e-03 GO:0007420 brain development
1.32 7.57e-03 GO:0040011 locomotion
1.30 8.21e-03 GO:0032879 regulation of localization
1.54 8.71e-03 GO:0022603 regulation of anatomical structure morphogenesis
2.50 8.84e-03 GO:0045995 regulation of embryonic development
1.42 9.43e-03 GO:0007417 central nervous system development
1.62 9.83e-03 GO:0003002 regionalization
1.34 1.05e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.53 1.19e-02 GO:0060284 regulation of cell development
1.71 1.32e-02 GO:0030900 forebrain development
1.45 2.28e-02 GO:0009968 negative regulation of signal transduction
1.70 2.51e-02 GO:0030155 regulation of cell adhesion
1.41 2.57e-02 GO:0019226 transmission of nerve impulse
1.41 2.57e-02 GO:0035637 multicellular organismal signaling
1.14 2.83e-02 GO:0080090 regulation of primary metabolic process
1.36 3.21e-02 GO:0010629 negative regulation of gene expression
1.46 3.39e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.24 3.62e-02 GO:0009893 positive regulation of metabolic process
1.56 4.56e-02 GO:0050767 regulation of neurogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.26 3.03e-08 GO:0044459 plasma membrane part
1.17 2.56e-07 GO:0071944 cell periphery
1.17 3.17e-07 GO:0005886 plasma membrane
1.48 1.04e-06 GO:0030054 cell junction
2.86 2.60e-04 GO:0042641 actomyosin
2.88 1.43e-03 GO:0001725 stress fiber
1.43 5.85e-03 GO:0045202 synapse
2.69 5.89e-03 GO:0032432 actin filament bundle
1.46 1.65e-02 GO:0005578 proteinaceous extracellular matrix
1.71 1.67e-02 GO:0043235 receptor complex
1.40 2.75e-02 GO:0031012 extracellular matrix
1.26 3.52e-02 GO:0042995 cell projection

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 1.19e-06 GO:0005515 protein binding
1.36 5.40e-06 GO:0001071 nucleic acid binding transcription factor activity
1.36 5.40e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.39 1.43e-04 GO:0043565 sequence-specific DNA binding
1.53 1.18e-03 GO:0016563 transcription activator activity
1.29 1.43e-03 GO:0030528 transcription regulator activity
1.38 4.07e-03 GO:0008324 cation transmembrane transporter activity
1.38 5.12e-03 GO:0008092 cytoskeletal protein binding
1.53 8.60e-03 GO:0005261 cation channel activity
1.30 1.98e-02 GO:0015075 ion transmembrane transporter activity