Motif ID: AAGGCAC

Z-value: 1.998


Mature miRNA associated with seed AAGGCAC:

NamemiRBase Accession
hsa-miR-124 MIMAT0000422
hsa-miR-506 MIMAT0002878



Activity profile for motif AAGGCAC.

activity profile for motif AAGGCAC


Sorted Z-values histogram for motif AAGGCAC

Sorted Z-values for motif AAGGCAC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGGCAC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_116166346 5.521 NM_001172896
NM_001172897
CAV1

caveolin 1, caveolae protein, 22kDa

chr7_+_116165043 5.308 NM_001172895
CAV1
caveolin 1, caveolae protein, 22kDa
chr7_+_116164838 5.294 NM_001753
CAV1
caveolin 1, caveolae protein, 22kDa
chr8_-_49833823 4.220 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr3_-_120169493 4.113 NM_007085
FSTL1
follistatin-like 1
chr4_+_169418167 4.113 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr19_-_50143350 3.914 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr4_+_169753105 3.881 NM_001166110
PALLD
palladin, cytoskeletal associated protein
chr4_+_169552752 3.865 NM_001166109
PALLD
palladin, cytoskeletal associated protein
chr17_-_767287 3.772 NM_001205319
NXN
nucleoredoxin
chr17_-_882905 3.583 NM_022463
NXN
nucleoredoxin
chr13_-_77460432 3.259 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr2_-_161350304 3.206 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr9_+_115913227 3.192 NM_001860
SLC31A2
solute carrier family 31 (copper transporters), member 2
chr1_-_225840660 3.162 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr20_-_14318200 3.068 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr17_+_48133331 2.953 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr3_-_32023237 2.913 NM_001174060
NM_017784
OSBPL10

oxysterol binding protein-like 10

chr5_-_16936371 2.861 NM_012334
MYO10
myosin X
chr1_+_223900061 2.847 NM_001748
CAPN2
calpain 2, (m/II) large subunit
chr9_+_706744 2.823 NM_153186
KANK1
KN motif and ankyrin repeat domains 1
chr6_-_169654047 2.816 NM_003247
THBS2
thrombospondin 2
chr7_+_79764087 2.774 NM_002069
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr9_+_504661 2.688 NM_015158
KANK1
KN motif and ankyrin repeat domains 1
chr13_-_110959441 2.592 NM_001845
COL4A1
collagen, type IV, alpha 1
chr6_-_134498973 2.556 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chrX_-_10588458 2.542 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr6_-_134639195 2.503 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr1_-_95392501 2.470 NM_001839
CNN3
calponin 3, acidic
chrX_-_10544852 2.405 NM_001193277
MID1
midline 1 (Opitz/BBB syndrome)
chrX_-_10645726 2.403 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr6_-_134496006 2.385 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr1_+_223889253 2.365 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr7_-_151574209 2.325 NM_016203
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr7_-_27183225 2.318 NM_019102
HOXA5
homeobox A5
chr20_-_43977023 2.300 NM_002999
SDC4
syndecan 4
chr10_+_17270257 2.295 NM_003380
VIM
vimentin
chr1_-_154946859 2.266 NM_001130041
NM_001202859
NM_003029
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chrX_-_10851808 2.240 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr9_-_14398981 2.237 NM_001190738
NFIB
nuclear factor I/B
chr7_-_151511925 2.159 NM_001040633
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr6_-_134497069 2.151 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr5_+_102201526 2.143 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chrX_+_134166318 2.123 NM_001078171
FAM127A
family with sequence similarity 127, member A
chr7_-_151329153 2.111 NM_024429
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr19_-_45909566 2.104 NM_001142502
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr12_+_78225068 2.071 NM_014903
NAV3
neuron navigator 3
chr1_+_7831326 2.050 NM_004781
VAMP3
vesicle-associated membrane protein 3 (cellubrevin)
chr20_-_56286540 2.050 NM_199171
PMEPA1
prostate transmembrane protein, androgen induced 1
chr9_+_124061880 2.032 NM_000177
GSN
gelsolin
chr12_-_15942350 1.994 NM_004447
EPS8
epidermal growth factor receptor pathway substrate 8
chr10_+_89419352 1.990 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr3_+_187943192 1.944 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr9_-_14314036 1.939 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr19_-_45908288 1.914 NM_006663
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr1_+_203595897 1.908 NM_001001396
NM_001684
ATP2B4

ATPase, Ca++ transporting, plasma membrane 4

chr2_-_169103886 1.898 NM_013233
STK39
serine threonine kinase 39
chr10_-_33247178 1.892 NM_002211
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr7_+_121513158 1.891 NM_001206838
NM_001206839
NM_002851
PTPRZ1


protein tyrosine phosphatase, receptor-type, Z polypeptide 1


chr11_+_832909 1.872 NM_001039490
NM_004357
NM_139029
NM_139030
CD151



CD151 molecule (Raph blood group)



chr10_-_30024594 1.855 NM_003174
SVIL
supervillin
chr16_+_69220940 1.844 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chrX_+_49028183 1.836 NM_002668
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr3_+_187871473 1.819 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr16_-_122573 1.801 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr10_-_33246786 1.794 NM_133376
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr3_-_69435429 1.788 NM_015123
FRMD4B
FERM domain containing 4B
chr12_-_48298765 1.788 NM_000376
NM_001017535
NM_001017536
VDR


vitamin D (1,25- dihydroxyvitamin D3) receptor


chr11_+_12695851 1.740 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr8_-_145013628 1.717 NM_201384
PLEC
plectin
chr12_-_110318178 1.711 NM_016433
GLTP
glycolipid transfer protein
chr8_-_145025043 1.711 NM_201380
PLEC
plectin
chr20_-_56285576 1.710 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr20_-_56284945 1.695 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr8_-_145027975 1.685 NM_201379
PLEC
plectin
chr3_+_187930720 1.666 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr15_-_30114536 1.649 NM_003257
NM_175610
TJP1

tight junction protein 1 (zona occludens 1)

chr8_-_145047639 1.646 NM_201378
PLEC
plectin
chr1_+_182992329 1.625 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr8_-_145018057 1.624 NM_201382
PLEC
plectin
chrX_-_106243442 1.581 NM_001085354
NM_024657
MORC4

MORC family CW-type zinc finger 4

chr1_-_154943001 1.574 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr8_-_145016691 1.571 NM_201383
PLEC
plectin
chr8_-_145018904 1.567 NM_201381
PLEC
plectin
chr9_-_107690526 1.549 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr10_+_129705299 1.545 NM_006504
PTPRE
protein tyrosine phosphatase, receptor type, E
chr19_+_39138265 1.527 NM_004924
ACTN4
actinin, alpha 4
chr21_+_18885104 1.522 NM_001207063
NM_001207064
NM_001207065
NM_001207066
NM_001338
CXADR




coxsackie virus and adenovirus receptor




chr9_+_124030370 1.515 NM_001127662
NM_001127663
NM_001127664
NM_001127665
NM_001127666
NM_001127667
NM_198252
GSN






gelsolin






chr9_-_110252045 1.503 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr10_+_129845806 1.501 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr2_+_241375030 1.485 NM_002081
GPC1
glypican 1
chr5_+_141488314 1.460 NM_030571
NDFIP1
Nedd4 family interacting protein 1
chr1_+_160175114 1.456 NM_003768
PEA15
phosphoprotein enriched in astrocytes 15
chr3_+_36421944 1.456 NM_003149
STAC
SH3 and cysteine rich domain
chr10_-_29923900 1.455 NM_021738
SVIL
supervillin
chr3_+_37903643 1.439 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr2_-_37899227 1.416 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr17_-_7298160 1.408 NM_001201576
NM_020360
PLSCR3

phospholipid scramblase 3

chr22_+_29702950 1.397 NM_006478
NM_152236
NM_152237
GAS2L1


growth arrest-specific 2 like 1


chr10_-_3827418 1.372 NM_001160124
NM_001160125
NM_001300
KLF6


Kruppel-like factor 6


chr11_+_19734821 1.371 NM_001244963
NM_145117
NM_182964
NAV2


neuron navigator 2


chr8_-_145050896 1.369 NM_000445
PLEC
plectin
chr18_+_11751470 1.363 NM_001142339
NM_002071
GNAL

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type

chr13_-_80915041 1.361 NM_005842
SPRY2
sprouty homolog 2 (Drosophila)
chr1_-_33168356 1.356 NM_001161708
NM_030786
SYNC

syncoilin, intermediate filament protein

chr3_-_133969563 1.320 NM_001005861
NM_002958
RYK

RYK receptor-like tyrosine kinase

chr19_-_10697907 1.319 NM_005498
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr10_+_102106771 1.317 NM_005063
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr14_+_104182045 1.306 NM_001198953
NM_024071
ZFYVE21

zinc finger, FYVE domain containing 21

chr2_-_110371669 1.304 NM_144710
NM_178584
SEPT10

septin 10

chr14_+_55034329 1.298 NM_001161576
NM_015589
SAMD4A

sterile alpha motif domain containing 4A

chr11_-_117166247 1.292 NM_001207048
NM_001207049
BACE1

beta-site APP-cleaving enzyme 1

chr12_+_56915587 1.264 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr4_-_122618140 1.235 NM_001154
ANXA5
annexin A5
chr15_+_90931470 1.230 NM_003870
IQGAP1
IQ motif containing GTPase activating protein 1
chr10_+_123923104 1.229 NM_006997
NM_206860
TACC2

transforming, acidic coiled-coil containing protein 2

chr5_+_82767492 1.212 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr10_+_123748688 1.209 NM_206861
NM_206862
TACC2

transforming, acidic coiled-coil containing protein 2

chr6_+_148663728 1.197 NM_015278
SASH1
SAM and SH3 domain containing 1
chr5_+_149340287 1.197 NM_000112
SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chr18_+_22006605 1.191 NM_018439
IMPACT
Impact homolog (mouse)
chr17_-_41174431 1.181 NM_006373
VAT1
vesicle amine transport protein 1 homolog (T. californica)
chr11_-_117186918 1.172 NM_012104
NM_138971
NM_138972
NM_138973
BACE1



beta-site APP-cleaving enzyme 1



chr17_+_72983723 1.162 NM_014603
CDR2L
cerebellar degeneration-related protein 2-like
chr3_+_11267666 1.159 NM_001098211
HRH1
histamine receptor H1
chr11_+_19372270 1.156 NM_001111018
NAV2
neuron navigator 2
chr8_+_9911797 1.147 NM_001135670
NM_012331
MSRA

methionine sulfoxide reductase A

chr1_+_64058891 1.128 NM_002633
PGM1
phosphoglucomutase 1
chr19_-_58609606 1.127 NM_001145543
NM_001145544
NM_023926
ZSCAN18


zinc finger and SCAN domain containing 18


chr7_+_128379345 1.127 NM_001130674
NM_001199671
NM_001199672
NM_001199673
NM_001199674
NM_001219
CALU





calumenin





chr1_+_180123906 1.120 NM_001004128
NM_002826
QSOX1

quiescin Q6 sulfhydryl oxidase 1

chr2_-_230135954 1.113 NM_001100818
NM_017933
PID1

phosphotyrosine interaction domain containing 1

chr22_-_38668966 1.111 NM_001195072
NM_012264
TMEM184B

transmembrane protein 184B

chr3_+_11294384 1.107 NM_000861
HRH1
histamine receptor H1
chr10_-_91011586 1.103 NM_000235
NM_001127605
LIPA

lipase A, lysosomal acid, cholesterol esterase

chr6_+_53659738 1.100 NM_018214
LRRC1
leucine rich repeat containing 1
chr12_-_89746244 1.100 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr14_-_105635114 1.097 NM_002226
NM_145159
JAG2

jagged 2

chr22_-_38668669 1.085 NM_001195071
TMEM184B
transmembrane protein 184B
chr1_+_64088886 1.078 NM_001172818
PGM1
phosphoglucomutase 1
chr7_+_17338182 1.075 NM_001621
AHR
aryl hydrocarbon receptor
chr22_-_36784055 1.058 NM_002473
MYH9
myosin, heavy chain 9, non-muscle
chr15_-_23086290 1.055 NM_144599
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr2_+_24272583 1.054 NM_004116
NM_054033
FKBP1B

FK506 binding protein 1B, 12.6 kDa

chr2_+_131674223 1.043 NM_015320
NM_032995
ARHGEF4

Rho guanine nucleotide exchange factor (GEF) 4

chr3_-_45187897 1.027 NM_022842
NM_178181
CDCP1

CUB domain containing protein 1

chr16_-_4166185 1.025 NM_001116
ADCY9
adenylate cyclase 9
chr9_-_99329092 1.007 NM_001077181
CDC14B
CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr7_-_42276617 1.007 NM_000168
GLI3
GLI family zinc finger 3
chr18_+_11689135 1.002 NM_182978
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr10_-_15413054 0.999 NM_001010924
FAM171A1
family with sequence similarity 171, member A1
chr19_-_58629762 0.998 NM_001145542
ZSCAN18
zinc finger and SCAN domain containing 18
chr4_-_40859081 0.997 NM_001166051
NM_001166052
NM_001166053
NM_001166054
APBB2



amyloid beta (A4) precursor protein-binding, family B, member 2



chr21_-_46293609 0.996 NM_004339
PTTG1IP
pituitary tumor-transforming 1 interacting protein
chr17_-_42907606 0.974 NM_005497
GJC1
gap junction protein, gamma 1, 45kDa
chr2_+_31456879 0.971 NM_014600
EHD3
EH-domain containing 3
chr8_-_57906423 0.962 NM_017813
IMPAD1
inositol monophosphatase domain containing 1
chr14_-_30396811 0.954 NM_002742
PRKD1
protein kinase D1
chr17_+_28705922 0.947 NM_001304
CPD
carboxypeptidase D
chr9_+_114423849 0.935 NM_001017998
NM_001198664
GNG10

guanine nucleotide binding protein (G protein), gamma 10

chr11_-_10562689 0.928 NM_016422
RNF141
ring finger protein 141
chr5_-_39425297 0.923 NM_001244871
NM_001343
DAB2

disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)

chr4_-_120549115 0.919 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr4_-_41216455 0.916 NM_001166050
NM_004307
NM_173075
APBB2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr18_-_61089695 0.916 NM_004869
VPS4B
vacuolar protein sorting 4 homolog B (S. cerevisiae)
chrX_+_66788682 0.915 NM_001011645
AR
androgen receptor
chr2_-_73340073 0.911 NM_015470
RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr8_+_9953061 0.911 NM_001135671
NM_001199729
MSRA

methionine sulfoxide reductase A

chr11_-_17191287 0.910 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr20_-_10654429 0.910 NM_000214
JAG1
jagged 1
chr3_+_50284325 0.903 NM_001166425
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr19_-_48867149 0.899 NM_018273
TMEM143
transmembrane protein 143
chr1_+_220701547 0.899 NM_018650
MARK1
MAP/microtubule affinity-regulating kinase 1
chr1_+_64059479 0.894 NM_001172819
PGM1
phosphoglucomutase 1
chr3_+_105085553 0.893 NM_001243280
NM_001243281
NM_001243283
NM_001627
ALCAM



activated leukocyte cell adhesion molecule



chr11_-_115375065 0.879 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr17_-_42908178 0.875 NM_001080383
GJC1
gap junction protein, gamma 1, 45kDa
chr9_-_124132503 0.875 NM_004099
NM_198194
STOM

stomatin

chr8_+_95732101 0.875 NM_181787
DPY19L4
dpy-19-like 4 (C. elegans)
chr14_-_75422466 0.873 NM_001207012
NM_002632
PGF

placental growth factor

chr12_+_26348268 0.869 NM_001135823
SSPN
sarcospan (Kras oncogene-associated gene)
chr17_+_52978022 0.868 NM_005486
TOM1L1
target of myb1 (chicken)-like 1
chr17_+_68165660 0.867 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr1_-_117664349 0.866 NM_001145635
NM_025188
TRIM45

tripartite motif containing 45

chr19_-_36523540 0.859 NM_001199570
CLIP3
CAP-GLY domain containing linker protein 3
chr2_+_70485204 0.854 NM_016297
PCYOX1
prenylcysteine oxidase 1
chr20_+_62496580 0.848 NM_001243891
NM_001243892
NM_001243894
NM_001243895
NM_003288
NM_199359
NM_199360
NM_199361
NM_199362
NM_199363
TPD52L2









tumor protein D52-like 2









chr6_+_86159301 0.847 NM_001204813
NM_002526
NT5E

5'-nucleotidase, ecto (CD73)

chr19_-_36523770 0.845 NM_015526
CLIP3
CAP-GLY domain containing linker protein 3
chr2_-_3523345 0.831 NM_018269
ADI1
acireductone dioxygenase 1
chr6_+_143999058 0.828 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr8_+_32579350 0.826 NM_001159996
NRG1
neuregulin 1
chr12_-_118541655 0.823 NM_019086
VSIG10
V-set and immunoglobulin domain containing 10
chr2_-_122042767 0.819 NM_014553
TFCP2L1
transcription factor CP2-like 1
chr15_+_69452799 0.814 NM_015554
GLCE
glucuronic acid epimerase
chr16_-_10674443 0.810 NM_001424
EMP2
epithelial membrane protein 2
chrX_-_134185978 0.807 NM_001078172
NM_001134321
FAM127B

family with sequence similarity 127, member B

chr9_-_99382073 0.807 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr1_+_93913566 0.802 NM_001024948
NM_001164473
NM_017737
FNBP1L


formin binding protein 1-like



Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.45 3.84e-02 GO:0000902 cell morphogenesis

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.13 2.34e-07 GO:0071944 cell periphery
9.77 2.15e-06 GO:0005912 adherens junction
2.04 4.50e-06 GO:0005886 plasma membrane
2.48 4.67e-06 GO:0044459 plasma membrane part
8.77 6.61e-06 GO:0070161 anchoring junction
6.86 2.38e-05 GO:0016323 basolateral plasma membrane
4.40 3.69e-05 GO:0030054 cell junction
10.42 1.33e-04 GO:0005925 focal adhesion
9.98 1.86e-04 GO:0005924 cell-substrate adherens junction
9.57 2.56e-04 GO:0030055 cell-substrate junction
8.90 8.00e-03 GO:0001726 ruffle
5.90 8.97e-03 GO:0031252 cell leading edge
2.37 1.08e-02 GO:0005856 cytoskeleton
2.27 4.13e-02 GO:0005887 integral to plasma membrane
2.25 4.91e-02 GO:0031226 intrinsic to plasma membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
4.33 1.53e-02 GO:0003779 actin binding
23.43 3.74e-02 GO:0050699 WW domain binding