Motif ID: AAGGUGC

Z-value: 1.219


Mature miRNA associated with seed AAGGUGC:

NamemiRBase Accession
hsa-miR-18a MIMAT0000072
hsa-miR-18b MIMAT0001412
hsa-miR-4735-3p MIMAT0019861



Activity profile for motif AAGGUGC.

activity profile for motif AAGGUGC


Sorted Z-values histogram for motif AAGGUGC

Sorted Z-values for motif AAGGUGC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGGUGC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_11382501 2.602 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr8_-_18871163 2.016 NM_015310
PSD3
pleckstrin and Sec7 domain containing 3
chr6_-_132272311 2.014 NM_001901
CTGF
connective tissue growth factor
chr4_-_186877869 2.004 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr8_-_18666295 1.914 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr2_+_36583369 1.907 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr4_-_186732208 1.890 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr15_-_60919642 1.847 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr5_-_73937248 1.747 NM_003633
ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr4_-_186732047 1.745 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr4_-_186733372 1.719 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr4_-_186697065 1.704 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr20_+_34700257 1.679 NM_177996
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr15_-_60884615 1.677 NM_134262
RORA
RAR-related orphan receptor A
chr15_-_61521478 1.671 NM_134261
RORA
RAR-related orphan receptor A
chr4_-_186578122 1.660 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr9_-_74383301 1.471 NM_001135820
NM_013390
TMEM2

transmembrane protein 2

chr6_+_39760148 1.420 NM_001201427
DAAM2
dishevelled associated activator of morphogenesis 2
chr6_-_11232901 1.404 NM_006403
NM_182966
NEDD9

neural precursor cell expressed, developmentally down-regulated 9

chr6_-_111136407 1.387 NM_015076
CDK19
cyclin-dependent kinase 19
chr3_+_105085553 1.344 NM_001243280
NM_001243281
NM_001243283
NM_001627
ALCAM



activated leukocyte cell adhesion molecule



chr22_+_38092994 1.302 NM_001039141
TRIOBP
TRIO and F-actin binding protein
chr14_+_62162042 1.302 NM_001530
NM_181054
HIF1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

chr6_-_16761600 1.279 NM_000332
NM_001128164
ATXN1

ataxin 1

chr20_+_34742656 1.215 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr3_-_124774735 1.134 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr9_-_132805456 1.127 NM_015033
FNBP1
formin binding protein 1
chr14_-_95623665 1.125 NM_177438
DICER1
dicer 1, ribonuclease type III
chr14_-_95608054 1.097 NM_030621
DICER1
dicer 1, ribonuclease type III
chr3_+_107241782 1.091 NM_001142568
NM_020235
BBX

bobby sox homolog (Drosophila)

chr17_+_40834571 1.088 NM_003632
CNTNAP1
contactin associated protein 1
chr11_+_108093558 1.075 NM_000051
ATM
ataxia telangiectasia mutated
chr19_-_23578226 1.058 NM_003430
ZNF91
zinc finger protein 91
chr3_+_187943192 1.050 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr6_+_39760772 1.048 NM_015345
DAAM2
dishevelled associated activator of morphogenesis 2
chr11_-_72852957 1.047 NM_014824
FCHSD2
FCH and double SH3 domains 2
chr3_+_187871473 1.047 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr10_-_735522 1.037 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr3_+_187930720 0.991 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr22_-_30642683 0.912 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr1_-_161993586 0.901 NM_015441
OLFML2B
olfactomedin-like 2B
chr11_-_2162340 0.876 NM_001127598
IGF2
insulin-like growth factor 2 (somatomedin A)
chr14_-_95599794 0.830 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr11_-_2170792 0.823 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr11_-_2160199 0.810 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr3_+_171757413 0.806 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr6_+_138188352 0.742 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr16_+_69599868 0.731 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr15_+_81071708 0.720 NM_018689
KIAA1199
KIAA1199
chr20_+_60697471 0.654 NM_144703
LSM14B
LSM14B, SCD6 homolog B (S. cerevisiae)
chr16_+_30960377 0.622 NM_152288
ORAI3
ORAI calcium release-activated calcium modulator 3
chr5_-_58334936 0.607 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr3_+_171758289 0.542 NM_001135095
FNDC3B
fibronectin type III domain containing 3B
chr2_-_26101301 0.538 NM_018263
ASXL2
additional sex combs like 2 (Drosophila)
chr22_+_38142230 0.521 NM_007032
NM_138632
TRIOBP

TRIO and F-actin binding protein

chr5_-_141993691 0.498 NM_033137
FGF1
fibroblast growth factor 1 (acidic)
chr15_-_56285732 0.472 NM_006154
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr5_-_58652671 0.468 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr20_+_30865435 0.468 NM_004798
KIF3B
kinesin family member 3B
chr10_-_81205091 0.455 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr2_+_28615771 0.417 NM_005253
FOSL2
FOS-like antigen 2
chr3_-_123603144 0.405 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr1_+_172502012 0.387 NM_014283
C1orf9
chromosome 1 open reading frame 9
chr7_+_137761177 0.368 NM_001190906
NM_001190907
NM_005989
AKR1D1


aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)


chr7_+_94536926 0.366 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory subunit 9A

chr2_+_24807345 0.361 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr17_-_76921453 0.356 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr1_+_163038395 0.355 NM_001102445
RGS4
regulator of G-protein signaling 4
chr20_-_43977023 0.353 NM_002999
SDC4
syndecan 4
chr1_-_120612301 0.350 NM_001200001
NM_024408
NOTCH2

notch 2

chr5_-_142000899 0.347 NM_001144892
FGF1
fibroblast growth factor 1 (acidic)
chr5_-_59189620 0.347 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_142065586 0.344 NM_000800
FGF1
fibroblast growth factor 1 (acidic)
chr17_+_48423382 0.338 NM_022167
XYLT2
xylosyltransferase II
chr7_+_94539209 0.334 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr15_+_39873276 0.332 NM_003246
THBS1
thrombospondin 1
chr5_-_142077508 0.326 NM_001144934
NM_001144935
FGF1

fibroblast growth factor 1 (acidic)

chr17_-_1394849 0.323 NM_033375
MYO1C
myosin IC
chr3_-_148939784 0.318 NM_000096
CP
ceruloplasmin (ferroxidase)
chr3_-_123339423 0.311 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr5_-_142065991 0.309 NM_033136
FGF1
fibroblast growth factor 1 (acidic)
chr3_+_37903643 0.308 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr1_+_163041694 0.308 NM_001113380
RGS4
regulator of G-protein signaling 4
chr13_-_38172862 0.307 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr15_-_34630203 0.306 NM_001042495
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr1_-_154155698 0.304 NM_001043351
NM_001043352
NM_001043353
NM_153649
TPM3



tropomyosin 3



chr2_+_30369749 0.294 NM_001127399
NM_001127400
NM_001127401
NM_016061
YPEL5



yippee-like 5 (Drosophila)



chr17_-_1395950 0.291 NM_001080779
MYO1C
myosin IC
chr17_-_1389013 0.288 NM_001080950
MYO1C
myosin IC
chr4_-_185395616 0.285 NM_002199
IRF2
interferon regulatory factor 2
chr15_-_34629044 0.282 NM_001042497
NM_133647
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chr10_+_111767685 0.282 NM_001121
NM_016824
ADD3

adducin 3 (gamma)

chr1_-_204329043 0.282 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr6_-_52441815 0.276 NM_012288
TRAM2
translocation associated membrane protein 2
chr1_+_172502291 0.274 NM_016227
C1orf9
chromosome 1 open reading frame 9
chr11_-_35441099 0.266 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr3_-_120401401 0.262 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr5_-_59064437 0.257 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_163038934 0.252 NM_001113381
RGS4
regulator of G-protein signaling 4
chr19_-_36523540 0.249 NM_001199570
CLIP3
CAP-GLY domain containing linker protein 3
chr5_-_142783225 0.248 NM_000176
NM_001020825
NM_001024094
NM_001204258
NM_001204259
NM_001204260
NM_001204261
NM_001204262
NM_001204263
NM_001204264
NM_001204265
NR3C1










nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)










chr11_-_34379526 0.246 NM_145804
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr1_+_163038564 0.245 NM_005613
RGS4
regulator of G-protein signaling 4
chr2_+_233561997 0.240 NM_001103146
NM_001103147
NM_001103148
NM_015575
GIGYF2



GRB10 interacting GYF protein 2



chr11_+_101983170 0.232 NM_001195045
YAP1
Yes-associated protein 1
chr17_+_46985720 0.230 NM_023079
UBE2Z
ubiquitin-conjugating enzyme E2Z
chr4_-_44728518 0.229 NM_138335
GNPDA2
glucosamine-6-phosphate deaminase 2
chr20_+_56884749 0.229 NM_020673
RAB22A
RAB22A, member RAS oncogene family
chr2_+_46926323 0.228 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr5_-_58571916 0.226 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_153032141 0.225 NM_005843
STAM2
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr15_-_34610928 0.218 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr2_-_64881040 0.217 NM_014755
SERTAD2
SERTA domain containing 2
chr19_-_19774501 0.211 NM_020410
ATP13A1
ATPase type 13A1
chr12_-_44200047 0.207 NM_001242397
NM_002822
TWF1

twinfilin, actin-binding protein, homolog 1 (Drosophila)

chr1_-_89530890 0.207 NM_002053
GBP1
guanylate binding protein 1, interferon-inducible
chr19_-_36523770 0.207 NM_015526
CLIP3
CAP-GLY domain containing linker protein 3
chr9_+_125703111 0.205 NM_012197
RABGAP1
RAB GTPase activating protein 1
chr5_-_151066492 0.202 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr10_-_119805673 0.198 NM_014904
RAB11FIP2
RAB11 family interacting protein 2 (class I)
chr6_+_52284948 0.198 NM_018100
EFHC1
EF-hand domain (C-terminal) containing 1
chr3_+_9975513 0.192 NM_015513
NM_001031717
NM_001077415
CRELD1


cysteine-rich with EGF-like domains 1


chr11_+_101980736 0.189 NM_001130145
NM_001195044
NM_006106
YAP1


Yes-associated protein 1


chr6_+_52285804 0.184 NM_001172420
EFHC1
EF-hand domain (C-terminal) containing 1
chr9_+_96338671 0.182 NM_005392
PHF2
PHD finger protein 2
chr12_-_106533810 0.179 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr19_-_7293876 0.178 NM_000208
NM_001079817
INSR

insulin receptor

chr19_+_50879681 0.178 NM_007121
NR1H2
nuclear receptor subfamily 1, group H, member 2
chr2_+_46926049 0.174 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr20_-_45280059 0.174 NM_001193339
NM_001193342
NM_022829
SLC13A3


solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3


chr6_+_26368405 0.173 NM_001197246
BTN3A2
butyrophilin, subfamily 3, member A2
chr3_+_127771126 0.173 NM_013336
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr14_+_32546445 0.169 NM_001030055
NM_001173
ARHGAP5

Rho GTPase activating protein 5

chr20_-_45313122 0.169 NM_001011554
NM_001193340
SLC13A3

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3

chr16_+_85645014 0.167 NM_001134473
KIAA0182
KIAA0182
chr4_-_83812334 0.166 NM_001191049
SEC31A
SEC31 homolog A (S. cerevisiae)
chr18_+_55862577 0.161 NM_001144970
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr1_+_87794150 0.159 NM_006769
LMO4
LIM domain only 4
chr4_-_7941092 0.158 NM_001134647
NM_198595
AFAP1

actin filament associated protein 1

chr9_-_99145991 0.157 NM_007001
SLC35D2
solute carrier family 35, member D2
chr6_+_26365397 0.157 NM_001197247
NM_001197249
NM_007047
NM_001197248
BTN3A2



butyrophilin, subfamily 3, member A2



chr10_-_79397546 0.157 NM_001014797
NM_001161352
NM_001161353
NM_002247
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr4_-_83812372 0.150 NM_001077206
NM_001077207
NM_001077208
NM_016211
NM_014933
SEC31A




SEC31 homolog A (S. cerevisiae)




chr19_+_4969123 0.148 NM_015015
KDM4B
lysine (K)-specific demethylase 4B
chr20_+_43595119 0.145 NM_006282
STK4
serine/threonine kinase 4
chr2_-_202316227 0.144 NM_015049
TRAK2
trafficking protein, kinesin binding 2
chr11_-_116968986 0.144 NM_025164
SIK3
SIK family kinase 3
chr18_+_55888750 0.143 NM_001144966
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr6_+_160769365 0.143 NM_021977
SLC22A3
solute carrier family 22 (extraneuronal monoamine transporter), member 3
chr3_-_185542807 0.142 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr18_+_55711388 0.141 NM_001144967
NM_001243960
NM_015277
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like


chr2_-_97405799 0.141 NM_001142292
NM_030805
LMAN2L

lectin, mannose-binding 2-like

chr8_+_104152876 0.136 NM_001024372
NM_024812
BAALC

brain and acute leukemia, cytoplasmic

chr16_+_28834407 0.134 NM_007245
NM_145714
NM_148414
NM_148415
NM_148416
ATXN2L




ataxin 2-like




chr3_+_183873253 0.133 NM_004423
DVL3
dishevelled, dsh homolog 3 (Drosophila)
chr3_-_13114547 0.132 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr18_+_55714457 0.128 NM_001144964
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr5_-_95297597 0.127 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr13_+_48807250 0.126 NM_021999
ITM2B
integral membrane protein 2B
chr2_-_85788644 0.126 NM_000821
NM_001142269
GGCX

gamma-glutamyl carboxylase

chr4_+_184020343 0.123 NM_024949
WWC2
WW and C2 domain containing 2
chr4_+_157997181 0.122 NM_000824
NM_001166061
NM_001166060
GLRB


glycine receptor, beta


chr15_-_23086290 0.120 NM_144599
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr17_-_56494930 0.119 NM_017763
RNF43
ring finger protein 43
chr8_-_23021447 0.118 NM_003840
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr16_+_3550916 0.115 NM_015041
CLUAP1
clusterin associated protein 1
chr1_+_220863627 0.111 NM_024709
C1orf115
chromosome 1 open reading frame 115
chr6_-_143266283 0.110 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr10_-_101945787 0.108 NM_001100626
ERLIN1
ER lipid raft associated 1
chr17_-_42201009 0.107 NM_001015053
NM_005474
HDAC5

histone deacetylase 5

chr3_-_113233952 0.106 NM_144718
SPICE1
spindle and centriole associated protein 1
chr1_+_145438437 0.105 NM_006472
TXNIP
thioredoxin interacting protein
chr15_-_90437616 0.103 NM_005829
AP3S2
adaptor-related protein complex 3, sigma 2 subunit
chr15_+_67430358 0.102 NM_001145103
SMAD3
SMAD family member 3
chr5_-_59783885 0.102 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_+_67458492 0.101 NM_001145104
SMAD3
SMAD family member 3
chr20_-_4982133 0.101 NM_005116
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr3_+_108308336 0.101 NM_014648
DZIP3
DAZ interacting protein 3, zinc finger
chr1_+_65886130 0.101 NM_001198683
NM_017526
LEPROT

leptin receptor overlapping transcript

chr20_-_4990913 0.100 NM_203327
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr20_+_306205 0.099 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr16_+_85646923 0.099 NM_014615
KIAA0182
KIAA0182
chr7_-_139477437 0.098 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr11_+_17373138 0.097 NM_001202439
B7H6
B7 homolog 6
chr9_+_115913227 0.096 NM_001860
SLC31A2
solute carrier family 31 (copper transporters), member 2
chr1_+_21766559 0.092 NM_032264
NBPF3
neuroblastoma breakpoint family, member 3
chr18_-_14132426 0.092 NM_145287
ZNF519
zinc finger protein 519
chr4_-_2263706 0.090 NM_006454
MXD4
MAX dimerization protein 4
chr18_-_3011944 0.088 NM_014646
LPIN2
lipin 2
chr18_+_55816546 0.086 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr6_-_49430851 0.085 NM_000255
MUT
methylmalonyl CoA mutase
chr20_+_32077904 0.084 NM_001032999
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr17_+_41363845 0.084 NM_145041
TMEM106A
transmembrane protein 106A
chr10_-_101945686 0.084 NM_006459
ERLIN1
ER lipid raft associated 1
chr10_+_102295572 0.084 NM_017902
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr9_+_120466453 0.082 NM_138554
TLR4
toll-like receptor 4
chr21_+_38071990 0.080 NM_005069
NM_009586
SIM2

single-minded homolog 2 (Drosophila)

chr14_+_24505620 0.080 NM_001082488
DHRS4L1
dehydrogenase/reductase (SDR family) member 4 like 1
chr7_-_64451413 0.078 NM_015852
ZNF117
zinc finger protein 117
chr21_-_36260972 0.078 NM_001001890
NM_001122607
RUNX1

runt-related transcription factor 1


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.