Motif ID: AAUCUCU

Z-value: 0.530


Mature miRNA associated with seed AAUCUCU:

NamemiRBase Accession
hsa-miR-216b MIMAT0004959



Activity profile for motif AAUCUCU.

activity profile for motif AAUCUCU


Sorted Z-values histogram for motif AAUCUCU

Sorted Z-values for motif AAUCUCU



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUCUCU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_60280462 0.420 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr17_-_29641094 0.395 NM_006495
EVI2B
ecotropic viral integration site 2B
chr6_-_33048554 0.386 NM_001242524
NM_001242525
HLA-DPA1

major histocompatibility complex, class II, DP alpha 1

chr6_-_33041266 0.334 NM_033554
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr17_-_47439326 0.316 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr16_+_8806825 0.308 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr17_+_53342320 0.294 NM_002126
HLF
hepatic leukemia factor
chr16_+_8814567 0.271 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr7_-_139477437 0.267 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr4_-_40631846 0.264 NM_001098634
RBM47
RNA binding motif protein 47
chr16_+_8768403 0.244 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr12_-_26985922 0.239 NM_002223
ITPR2
inositol 1,4,5-trisphosphate receptor, type 2
chr8_-_22550708 0.232 NM_004430
EGR3
early growth response 3
chr15_-_61521478 0.227 NM_134261
RORA
RAR-related orphan receptor A
chr18_+_13611664 0.225 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr7_-_44924946 0.224 NM_033224
PURB
purine-rich element binding protein B
chr18_+_13218777 0.224 NM_181481
NM_181482
C18orf1

chromosome 18 open reading frame 1

chr4_-_40517913 0.222 NM_019027
RBM47
RNA binding motif protein 47
chr18_+_13620866 0.221 NM_004338
NM_181483
C18orf1

chromosome 18 open reading frame 1

chr2_-_214016332 0.209 NM_001079526
IKZF2
IKAROS family zinc finger 2 (Helios)
chr15_-_60884615 0.207 NM_134262
RORA
RAR-related orphan receptor A
chr8_-_22550057 0.203 NM_001199881
EGR3
early growth response 3
chr2_+_110371887 0.201 NM_023016
ANKRD57
ankyrin repeat domain 57
chr14_+_71108373 0.199 NM_015351
TTC9
tetratricopeptide repeat domain 9
chr2_-_214015053 0.195 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr2_-_242212244 0.193 NM_001243900
NM_203346
HDLBP

high density lipoprotein binding protein

chr8_-_22549901 0.192 NM_001199880
EGR3
early growth response 3
chr7_+_89840999 0.190 NM_001244944
NM_001244945
NM_152999
NM_001040665
NM_001244946
STEAP2




STEAP family member 2, metalloreductase




chr2_+_75059781 0.188 NM_000189
HK2
hexokinase 2
chr9_-_5833072 0.183 NM_024896
ERMP1
endoplasmic reticulum metallopeptidase 1
chr11_-_35441099 0.180 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr15_-_60919642 0.177 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr11_-_35441501 0.175 NM_001195728
NM_001252652
SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

chr6_+_111195986 0.168 NM_001634
NM_001033059
AMD1

adenosylmethionine decarboxylase 1

chr6_+_160769365 0.163 NM_021977
SLC22A3
solute carrier family 22 (extraneuronal monoamine transporter), member 3
chr15_-_70994608 0.159 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr1_-_200992824 0.158 NM_001252100
NM_001252102
NM_001252103
NM_017596
KIF21B



kinesin family member 21B



chr7_+_94536926 0.156 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory subunit 9A

chr18_-_67624159 0.156 NM_006566
CD226
CD226 molecule
chr7_+_94285676 0.152 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr6_+_42788793 0.151 NM_015349
KIAA0240
KIAA0240
chr3_-_48700317 0.149 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr4_+_78078332 0.148 NM_004354
CCNG2
cyclin G2
chr8_+_28351694 0.148 NM_017412
NM_145866
FZD3

frizzled family receptor 3

chr7_+_94285620 0.147 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr4_-_88141614 0.146 NM_020803
KLHL8
kelch-like 8 (Drosophila)
chr2_+_113885137 0.146 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr19_+_54041332 0.145 NM_001079906
NM_001253798
NM_001253799
ZNF331


zinc finger protein 331


chr12_-_57030083 0.144 NM_013449
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr7_+_89975977 0.140 NM_001042717
NM_033107
GTPBP10

GTP-binding protein 10 (putative)

chr22_+_24891114 0.136 NM_016327
UPB1
ureidopropionase, beta
chr20_+_46130600 0.135 NM_001174087
NM_001174088
NM_006534
NM_181659
NCOA3



nuclear receptor coactivator 3



chr5_+_68800003 0.134 NM_001205255
OCLN
occludin
chr17_-_73975507 0.133 NM_001185039
NM_004035
NM_007292
ACOX1


acyl-CoA oxidase 1, palmitoyl


chr7_+_21467572 0.131 NM_003112
SP4
Sp4 transcription factor
chr1_+_167189948 0.131 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr8_-_79717540 0.130 NM_000880
NM_001199886
NM_001199887
NM_001199888
IL7



interleukin 7



chr19_+_54058493 0.130 NM_001079907
ZNF331
zinc finger protein 331
chr12_+_11802726 0.128 NM_001987
ETV6
ets variant 6
chr2_+_113875469 0.126 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr15_-_71055745 0.126 NM_018003
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr1_+_167298280 0.124 NM_001198783
POU2F1
POU class 2 homeobox 1
chr6_+_114178516 0.124 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr1_-_154842725 0.122 NM_001204087
NM_002249
KCNN3

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

chr3_-_121553907 0.121 NM_001023570
NM_001023571
IQCB1

IQ motif containing B1

chr21_-_19191643 0.120 NM_001100420
NM_001100421
NM_017447
C21orf91


chromosome 21 open reading frame 91


chr5_+_142150291 0.118 NM_001135608
NM_015071
ARHGAP26

Rho GTPase activating protein 26

chr12_-_102872329 0.117 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr5_+_94890777 0.114 NM_198150
ARSK
arylsulfatase family, member K
chr19_+_54024176 0.113 NM_018555
ZNF331
zinc finger protein 331
chr1_-_151882360 0.111 NM_053055
THEM4
thioesterase superfamily member 4
chr19_+_34855594 0.110 NM_001184722
NM_000175
GPI

glucose-6-phosphate isomerase

chr19_+_57702833 0.110 NM_003417
ZNF264
zinc finger protein 264
chr1_-_146644045 0.109 NM_005399
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr7_+_134212343 0.109 NM_020299
AKR1B10
aldo-keto reductase family 1, member B10 (aldose reductase)
chr3_+_142342265 0.108 NM_002670
PLS1
plastin 1
chr7_+_94539209 0.108 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr15_+_73344824 0.105 NM_001172623
NM_001172624
NM_002499
NEO1


neogenin 1


chr3_+_142375738 0.104 NM_001172312
PLS1
plastin 1
chr2_+_173420776 0.102 NM_002610
PDK1
pyruvate dehydrogenase kinase, isozyme 1
chr4_-_57301643 0.102 NM_002703
PPAT
phosphoribosyl pyrophosphate amidotransferase
chr3_+_142315205 0.101 NM_001145319
PLS1
plastin 1
chr3_-_57199402 0.101 NM_017563
IL17RD
interleukin 17 receptor D
chr12_+_111471827 0.100 NM_015267
CUX2
cut-like homeobox 2
chr1_-_114354906 0.100 NM_018364
RSBN1
round spermatid basic protein 1
chr7_+_7222142 0.099 NM_020156
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr7_+_102937869 0.096 NM_004279
PMPCB
peptidase (mitochondrial processing) beta
chrX_-_119445306 0.096 NM_001104544
NM_001104545
NM_017938
FAM70A


family with sequence similarity 70, member A


chr1_-_231560789 0.096 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr4_-_13629270 0.095 NM_148894
BOD1L
biorientation of chromosomes in cell division 1-like
chr19_+_54466289 0.094 NM_031895
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr14_+_71374111 0.094 NM_014982
PCNX
pecanex homolog (Drosophila)
chr20_-_45280059 0.094 NM_001193339
NM_001193342
NM_022829
SLC13A3


solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3


chr8_+_42752019 0.093 NM_032410
HOOK3
hook homolog 3 (Drosophila)
chr14_+_102228134 0.093 NM_001161725
NM_001161726
PPP2R5C

protein phosphatase 2, regulatory subunit B', gamma

chr4_+_39046198 0.091 NM_001007075
NM_001171654
KLHL5

kelch-like 5 (Drosophila)

chr14_+_24899139 0.090 NM_015299
KHNYN
KH and NYN domain containing
chr17_-_65241305 0.090 NM_014877
HELZ
helicase with zinc finger
chr15_+_91643181 0.089 NM_001167580
SV2B
synaptic vesicle glycoprotein 2B
chr20_-_45313122 0.089 NM_001011554
NM_001193340
SLC13A3

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3

chr13_-_74707913 0.088 NM_007249
KLF12
Kruppel-like factor 12
chr22_+_18632704 0.088 NM_017414
USP18
ubiquitin specific peptidase 18
chr16_-_10276115 0.087 NM_001134407
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr4_+_39063851 0.087 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr5_+_68788387 0.086 NM_001205254
OCLN
occludin
chr16_-_19729417 0.084 NM_001012991
C16orf88
chromosome 16 open reading frame 88
chr16_-_57520326 0.083 NM_018110
DOK4
docking protein 4
chr16_+_12995454 0.083 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr12_-_8088629 0.081 NM_006931
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr1_-_100715388 0.081 NM_001918
DBT
dihydrolipoamide branched chain transacylase E2
chr12_+_27397077 0.080 NM_015000
STK38L
serine/threonine kinase 38 like
chr3_+_141043054 0.080 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr15_+_42867708 0.079 NM_020759
STARD9
StAR-related lipid transfer (START) domain containing 9
chr7_-_129845216 0.079 NM_032842
TMEM209
transmembrane protein 209
chr4_+_40058507 0.079 NM_018177
N4BP2
NEDD4 binding protein 2
chr12_+_9822205 0.078 NM_001197318
NM_013269
NM_001004419
NM_001197317
NM_001197319
CLEC2D




C-type lectin domain family 2, member D




chr3_+_57261729 0.077 NM_012096
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr2_+_73441344 0.076 NM_006062
SMYD5
SMYD family member 5
chr15_-_42840992 0.075 NM_153260
LRRC57
leucine rich repeat containing 57
chr3_+_180319898 0.075 NM_001042601
NM_133462
TTC14

tetratricopeptide repeat domain 14

chr20_+_49126857 0.075 NM_002827
PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr5_+_68788118 0.075 NM_002538
OCLN
occludin
chr16_-_10276610 0.075 NM_000833
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr1_-_220263150 0.074 NM_006085
BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1
chr16_-_30457197 0.073 NM_012248
SEPHS2
selenophosphate synthetase 2
chr3_+_14989076 0.072 NM_003298
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr1_+_228353428 0.071 NM_001010867
IBA57
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr22_+_40440664 0.070 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr1_-_154832187 0.070 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr2_+_238600780 0.069 NM_001137551
NM_001137552
NM_001137553
NM_004735
LRRFIP1



leucine rich repeat (in FLII) interacting protein 1



chr11_+_119076974 0.068 NM_005188
CBL
Cas-Br-M (murine) ecotropic retroviral transforming sequence
chr20_+_32951054 0.068 NM_031483
ITCH
itchy E3 ubiquitin protein ligase homolog (mouse)
chr16_-_67840464 0.068 NM_020850
RANBP10
RAN binding protein 10
chr9_+_137218313 0.068 NM_002957
RXRA
retinoid X receptor, alpha
chr2_-_242255114 0.067 NM_005336
HDLBP
high density lipoprotein binding protein
chr6_+_13574649 0.065 NM_001193267
NM_001242827
NM_031244
NM_012241
SIRT5



sirtuin 5



chrX_+_24073060 0.065 NM_001415
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr3_-_113233952 0.064 NM_144718
SPICE1
spindle and centriole associated protein 1
chr9_+_87283453 0.063 NM_001018064
NM_006180
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr13_-_21476895 0.063 NM_022459
XPO4
exportin 4
chr11_+_108093558 0.063 NM_000051
ATM
ataxia telangiectasia mutated
chr12_+_5019048 0.062 NM_000217
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr17_+_61627818 0.061 NM_005828
DCAF7
DDB1 and CUL4 associated factor 7
chr15_+_91643429 0.060 NM_014848
SV2B
synaptic vesicle glycoprotein 2B
chr9_-_111696556 0.059 NM_003640
IKBKAP
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chr22_+_39898248 0.059 NM_019008
SMCR7L
Smith-Magenis syndrome chromosome region, candidate 7-like
chr11_-_129062092 0.059 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr20_+_30697291 0.059 NM_014742
TM9SF4
transmembrane 9 superfamily protein member 4
chr1_+_53192021 0.059 NM_024646
ZYG11B
zyg-11 homolog B (C. elegans)
chr4_+_37892698 0.059 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr11_+_92085261 0.059 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr11_-_18655962 0.059 NM_194285
SPTY2D1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr20_+_57226287 0.058 NM_001001433
NM_001134772
NM_001134773
NM_001204868
NM_003763
STX16-NPEPL1
STX16




STX16-NPEPL1 readthrough (non-protein coding)
syntaxin 16




chr22_+_40573879 0.058 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr16_+_19125243 0.058 NM_001034841
ITPRIPL2
inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr15_-_75743776 0.057 NM_015477
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr2_-_148779172 0.057 NM_181742
ORC4
origin recognition complex, subunit 4
chr17_+_18684579 0.056 NM_016078
FAM18B1
family with sequence similarity 18, member B1
chr19_-_23941571 0.056 NM_138286
ZNF681
zinc finger protein 681
chr21_+_38739858 0.052 NM_101395
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr15_-_34629941 0.052 NM_001042494
NM_001042496
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chr12_-_108733075 0.052 NM_001142343
NM_001142344
NM_004072
CMKLR1


chemokine-like receptor 1


chr2_-_176866925 0.051 NM_030650
KIAA1715
KIAA1715
chr9_+_33264876 0.051 NM_001195536
NM_016410
CHMP5

charged multivesicular body protein 5

chr1_-_52831817 0.051 NM_032449
CC2D1B
coiled-coil and C2 domain containing 1B
chr1_-_116383323 0.050 NM_001111061
NHLH2
nescient helix loop helix 2
chr17_+_46018888 0.050 NM_018129
PNPO
pyridoxamine 5'-phosphate oxidase
chr18_-_29264394 0.050 NM_004775
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr9_-_36258383 0.050 NM_001190383
NM_001190384
NM_005476
GNE


glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase


chr12_-_108714438 0.050 NM_001142345
CMKLR1
chemokine-like receptor 1
chr7_-_92463211 0.049 NM_001259
CDK6
cyclin-dependent kinase 6
chr1_+_47799447 0.049 NM_001136140
NM_016308
CMPK1

cytidine monophosphate (UMP-CMP) kinase 1, cytosolic

chr15_-_34610928 0.049 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr5_+_130506635 0.047 NM_181705
LYRM7
Lyrm7 homolog (mouse)
chr7_-_138665853 0.047 NM_001164665
NM_020910
KIAA1549

KIAA1549

chr4_+_99916787 0.045 NM_015143
METAP1
methionyl aminopeptidase 1
chr16_-_46723111 0.045 NM_018206
VPS35
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr2_-_148778262 0.045 NM_001190882
NM_001190879
NM_002552
NM_001190881
NM_181741
ORC4




origin recognition complex, subunit 4




chr2_-_239197091 0.044 NM_022817
PER2
period homolog 2 (Drosophila)
chr19_-_52531517 0.044 NM_025040
ZNF614
zinc finger protein 614
chr7_-_92465929 0.044 NM_001145306
CDK6
cyclin-dependent kinase 6
chr1_-_204329043 0.044 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr12_+_68042493 0.043 NM_003583
NM_006482
DYRK2

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2

chr10_+_72163860 0.043 NM_004096
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chrX_+_147582133 0.042 NM_001169122
NM_001169123
NM_001169124
NM_001169125
NM_002025
AFF2




AF4/FMR2 family, member 2




chr6_+_26365397 0.042 NM_001197247
NM_001197249
NM_007047
NM_001197248
BTN3A2



butyrophilin, subfamily 3, member A2



chr14_+_64932216 0.042 NM_004857
AKAP5
A kinase (PRKA) anchor protein 5
chr8_+_48872762 0.041 NM_005914
NM_182746
MCM4

minichromosome maintenance complex component 4

chr6_+_26368405 0.041 NM_001197246
BTN3A2
butyrophilin, subfamily 3, member A2
chr1_-_236030219 0.040 NM_000081
LYST
lysosomal trafficking regulator
chr1_-_216596737 0.040 NM_007123
NM_206933
USH2A

Usher syndrome 2A (autosomal recessive, mild)

chr5_-_141016328 0.039 NM_003883
HDAC3
histone deacetylase 3
chr11_-_128894008 0.039 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr1_-_109935869 0.038 NM_001205228
SORT1
sortilin 1
chr3_-_171528227 0.038 NM_001130081
NM_002662
PLD1

phospholipase D1, phosphatidylcholine-specific

chr2_-_228029274 0.037 NM_000092
COL4A4
collagen, type IV, alpha 4
chr19_+_44645708 0.037 NM_001144824
NM_006630
ZNF234

zinc finger protein 234

chr9_+_4985243 0.037 NM_004972
JAK2
Janus kinase 2
chr17_-_63052884 0.037 NM_006572
GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr2_+_166428845 0.037 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.