Motif ID: AAUGCCC

Z-value: 1.109


Mature miRNA associated with seed AAUGCCC:

NamemiRBase Accession
hsa-miR-365 MIMAT0000710



Activity profile for motif AAUGCCC.

activity profile for motif AAUGCCC


Sorted Z-values histogram for motif AAUGCCC

Sorted Z-values for motif AAUGCCC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUGCCC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_123603144 3.173 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr3_-_123339423 3.106 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr2_-_158732341 2.084 NM_001111067
ACVR1
activin A receptor, type I
chr2_-_158731622 1.844 NM_001105
ACVR1
activin A receptor, type I
chr9_-_14398981 1.655 NM_001190738
NFIB
nuclear factor I/B
chr2_-_56151273 1.449 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr15_+_33010174 1.372 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr10_+_75670861 1.361 NM_001145031
NM_002658
PLAU

plasminogen activator, urokinase

chr6_-_134498973 1.351 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr9_-_14314036 1.311 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr6_-_134639195 1.218 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_134496006 1.195 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr11_-_27681195 1.175 NM_001143816
NM_170735
BDNF

brain-derived neurotrophic factor

chr3_-_55521330 1.151 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr12_+_72666462 1.101 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr11_-_27722446 1.098 NM_001143812
BDNF
brain-derived neurotrophic factor
chr6_-_134497069 1.079 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr11_-_27721179 1.075 NM_170734
BDNF
brain-derived neurotrophic factor
chr11_+_69455837 1.068 NM_053056
CCND1
cyclin D1
chr11_-_27722599 1.060 NM_001143808
NM_001143809
NM_001143810
NM_001143811
BDNF



brain-derived neurotrophic factor




Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 25 entries
Enrichment   P-value GO Accession GO Term
324.38 4.04e-03 GO:0033598 mammary gland epithelial cell proliferation
149.76 2.09e-02 GO:0033628 regulation of cell adhesion mediated by integrin
149.76 2.09e-02 GO:0050922 negative regulation of chemotaxis
108.18 4.09e-02 GO:0048521 negative regulation of behavior
60.88 3.63e-03 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
41.48 4.49e-04 GO:0061138 morphogenesis of a branching epithelium
35.14 8.74e-04 GO:0001763 morphogenesis of a branching structure
35.14 8.74e-04 GO:0051384 response to glucocorticoid stimulus
33.63 2.18e-02 GO:0048754 branching morphogenesis of a tube
32.51 1.19e-03 GO:0031960 response to corticosteroid stimulus
29.56 3.20e-02 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
26.02 2.90e-03 GO:0035239 tube morphogenesis
21.11 6.64e-03 GO:0002009 morphogenesis of an epithelium
20.43 5.49e-04 GO:0048729 tissue morphogenesis
17.37 1.43e-02 GO:0035295 tube development
16.74 1.47e-03 GO:0060429 epithelium development
15.90 2.03e-02 GO:0048545 response to steroid hormone stimulus
13.73 3.59e-02 GO:0048598 embryonic morphogenesis
12.36 6.47e-03 GO:0072358 cardiovascular system development
12.36 6.47e-03 GO:0072359 circulatory system development

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
7.39 8.82e-03 GO:0005615 extracellular space
5.89 2.57e-02 GO:0044421 extracellular region part
4.17 3.96e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
9.77 2.20e-03 GO:0004672 protein kinase activity
8.14 5.26e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
7.60 7.34e-03 GO:0016301 kinase activity
6.55 1.47e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
5.83 2.56e-02 GO:0005102 receptor binding