Motif ID: ACAGUAU

Z-value: 0.844


Mature miRNA associated with seed ACAGUAU:

NamemiRBase Accession
hsa-miR-144 MIMAT0000436



Activity profile for motif ACAGUAU.

activity profile for motif ACAGUAU


Sorted Z-values histogram for motif ACAGUAU

Sorted Z-values for motif ACAGUAU



Network of associatons between targets according to the STRING database.



First level regulatory network of ACAGUAU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_41166931 2.955 NM_003012
SFRP1
secreted frizzled-related protein 1
chrX_+_102631267 2.732 NM_206915
NM_206917
NGFRAP1

nerve growth factor receptor (TNFRSF16) associated protein 1

chrX_+_102632108 2.622 NM_014380
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr16_-_65155881 2.397 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr5_+_52776263 2.150 NM_006350
NM_013409
FST

follistatin

chr5_-_127873734 2.064 NM_001999
FBN2
fibrillin 2
chr15_+_101420004 2.036 NM_000693
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr2_-_216300770 2.023 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr1_-_95392501 1.951 NM_001839
CNN3
calponin 3, acidic
chr8_-_42065193 1.888 NM_000930
NM_033011
PLAT

plasminogen activator, tissue

chr2_-_235405692 1.672 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr6_+_121756744 1.567 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr9_+_112542496 1.411 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr12_+_13349601 1.328 NM_001423
EMP1
epithelial membrane protein 1
chr3_+_30647901 1.307 NM_001024847
NM_003242
TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

chr1_-_68299047 1.269 NM_018841
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr8_+_79428335 1.219 NM_006823
NM_181839
PKIA

protein kinase (cAMP-dependent, catalytic) inhibitor alpha

chr4_-_7941092 1.211 NM_001134647
NM_198595
AFAP1

actin filament associated protein 1

chr9_+_132962871 1.198 NM_001128826
NCS1
neuronal calcium sensor 1
chr13_-_77460432 1.195 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr12_+_4430346 1.179 NM_020375
C12orf5
chromosome 12 open reading frame 5
chr15_+_39873276 1.141 NM_003246
THBS1
thrombospondin 1
chr2_-_227663454 1.105 NM_005544
IRS1
insulin receptor substrate 1
chr10_-_126716452 1.101 NM_022802
CTBP2
C-terminal binding protein 2
chr20_-_14318200 1.090 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr13_-_107187312 1.075 NM_004093
EFNB2
ephrin-B2
chr10_-_126849066 1.069 NM_001329
CTBP2
C-terminal binding protein 2
chr3_-_98620452 1.045 NM_080927
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr9_+_112887780 1.025 NM_001136562
AKAP2
A kinase (PRKA) anchor protein 2
chr6_+_114178516 1.024 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr10_-_126849556 1.008 NM_001083914
CTBP2
C-terminal binding protein 2
chr9_+_112810877 0.966 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr4_-_99579540 0.965 NM_005723
TSPAN5
tetraspanin 5
chr14_-_52535945 0.951 NM_007361
NID2
nidogen 2 (osteonidogen)
chr15_-_48937795 0.884 NM_000138
FBN1
fibrillin 1
chr10_+_8096633 0.838 NM_001002295
NM_002051
GATA3

GATA binding protein 3

chr3_+_36421944 0.789 NM_003149
STAC
SH3 and cysteine rich domain
chr13_-_110959441 0.777 NM_001845
COL4A1
collagen, type IV, alpha 1
chr2_-_188312872 0.763 NM_005795
CALCRL
calcitonin receptor-like
chr8_+_136469557 0.762 NM_006558
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr18_+_56530060 0.754 NM_018181
ZNF532
zinc finger protein 532
chr1_-_225840660 0.740 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr7_+_116140097 0.733 NM_001206748
CAV2
caveolin 2
chr14_+_85996454 0.722 NM_013231
FLRT2
fibronectin leucine rich transmembrane protein 2
chr9_-_107690526 0.714 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr15_-_52821004 0.714 NM_000259
NM_001142495
MYO5A

myosin VA (heavy chain 12, myoxin)

chr7_+_116139619 0.713 NM_001206747
NM_001233
NM_198212
CAV2


caveolin 2


chr1_+_169075869 0.710 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr9_+_132934685 0.697 NM_014286
NCS1
neuronal calcium sensor 1
chr17_+_48133331 0.695 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr7_-_47621741 0.690 NM_022748
TNS3
tensin 3
chr21_-_27543134 0.668 NM_000484
NM_001136129
NM_001136130
NM_001204301
NM_001204302
NM_001204303
NM_201413
NM_201414
APP







amyloid beta (A4) precursor protein







chr1_-_186649421 0.662 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr21_-_43346780 0.652 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr21_-_27543445 0.635 NM_001136131
APP
amyloid beta (A4) precursor protein
chr12_+_78225068 0.630 NM_014903
NAV3
neuron navigator 3
chr9_+_128509616 0.606 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr5_-_38595506 0.604 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr18_+_8717368 0.603 NM_015210
CCDC165
coiled-coil domain containing 165
chr4_+_126237566 0.595 NM_024582
FAT4
FAT tumor suppressor homolog 4 (Drosophila)
chr19_-_58609606 0.583 NM_001145543
NM_001145544
NM_023926
ZSCAN18


zinc finger and SCAN domain containing 18


chr4_+_78078332 0.577 NM_004354
CCNG2
cyclin G2
chr9_-_14398981 0.562 NM_001190738
NFIB
nuclear factor I/B
chr12_-_76425375 0.559 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr8_-_60031545 0.555 NM_014729
TOX
thymocyte selection-associated high mobility group box
chr7_-_131241321 0.553 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr2_+_66662516 0.552 NM_002398
MEIS1
Meis homeobox 1
chr6_-_134639195 0.548 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_134498973 0.547 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr9_+_128510477 0.542 NM_001134778
PBX3
pre-B-cell leukemia homeobox 3
chr3_+_150321065 0.539 NM_016275
SELT
selenoprotein T
chr15_+_25068793 0.537 NM_022806
NM_022807
NM_022808
SNRPN


small nuclear ribonucleoprotein polypeptide N


chrX_+_51486479 0.531 NM_018094
GSPT2
G1 to S phase transition 2
chr15_+_96875793 0.523 NM_001145156
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr16_-_17564737 0.523 NM_022166
XYLT1
xylosyltransferase I
chr15_+_25101697 0.518 NM_022805
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr16_+_69220940 0.516 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr6_-_134496006 0.515 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr15_-_59665069 0.513 NM_004998
MYO1E
myosin IE
chr10_+_63661012 0.509 NM_032199
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr19_-_58629762 0.508 NM_001145542
ZSCAN18
zinc finger and SCAN domain containing 18
chr21_-_27512668 0.500 NM_001136016
APP
amyloid beta (A4) precursor protein
chr11_-_8832881 0.499 NM_139157
ST5
suppression of tumorigenicity 5
chr11_-_8932497 0.497 NM_005418
ST5
suppression of tumorigenicity 5
chr9_-_14314036 0.496 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr6_-_134497069 0.477 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr16_-_74641014 0.472 NM_001145666
NM_001145667
NM_012201
GLG1


golgi glycoprotein 1


chr3_-_149421059 0.464 NM_001168278
WWTR1
WW domain containing transcription regulator 1
chr11_+_9685624 0.464 NM_015055
SWAP70
SWAP switching B-cell complex 70kDa subunit
chr9_-_16870719 0.461 NM_017637
BNC2
basonuclin 2
chr2_-_190044330 0.460 NM_000393
COL5A2
collagen, type V, alpha 2
chr16_+_66400524 0.445 NM_001795
CDH5
cadherin 5, type 2 (vascular endothelium)
chrX_-_99891690 0.439 NM_003270
TSPAN6
tetraspanin 6
chr16_-_10674443 0.438 NM_001424
EMP2
epithelial membrane protein 2
chr2_-_37899227 0.420 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr8_+_61429390 0.415 NM_001242644
NM_002865
RAB2A

RAB2A, member RAS oncogene family

chr1_+_82266081 0.413 NM_012302
LPHN2
latrophilin 2
chr7_+_18126543 0.411 NM_001204144
HDAC9
histone deacetylase 9
chr3_-_149375584 0.405 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr7_+_18548899 0.401 NM_001204147
NM_001204148
HDAC9

histone deacetylase 9

chr11_+_69924407 0.401 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr9_-_123476578 0.390 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr5_-_38556682 0.390 NM_001127671
LIFR
leukemia inhibitory factor receptor alpha
chr16_+_86544104 0.385 NM_001451
FOXF1
forkhead box F1
chr3_-_124774735 0.375 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr12_-_26277807 0.371 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr15_+_96876568 0.370 NM_001145157
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr3_+_51428698 0.367 NM_013286
RBM15B
RNA binding motif protein 15B
chr11_-_8832189 0.366 NM_213618
ST5
suppression of tumorigenicity 5
chr17_-_78450247 0.363 NM_002522
NPTX1
neuronal pentraxin I
chr15_-_83876165 0.362 NM_016073
HDGFRP3
hepatoma-derived growth factor, related protein 3
chr22_+_33196801 0.361 NM_000362
TIMP3
TIMP metallopeptidase inhibitor 3
chr14_-_54955714 0.359 NM_004124
GMFB
glia maturation factor, beta
chr3_-_136471186 0.345 NM_005862
STAG1
stromal antigen 1
chr6_+_89790412 0.332 NM_006813
PNRC1
proline-rich nuclear receptor coactivator 1
chr12_-_57505176 0.325 NM_001178078
NM_001178080
NM_001178081
NM_003153
STAT6



signal transducer and activator of transcription 6, interleukin-4 induced



chr16_+_67927170 0.324 NM_006742
PSKH1
protein serine kinase H1
chr7_+_116312412 0.321 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr1_+_155829259 0.320 NM_152280
SYT11
synaptotagmin XI
chr20_+_11871364 0.320 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr7_-_27213873 0.317 NM_018951
HOXA10
homeobox A10
chr15_+_96873845 0.313 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr6_+_148663728 0.302 NM_015278
SASH1
SAM and SH3 domain containing 1
chr19_+_18794391 0.301 NM_001098482
NM_015321
CRTC1

CREB regulated transcription coactivator 1

chr2_-_70781146 0.297 NM_001099691
NM_003236
TGFA

transforming growth factor, alpha

chr1_+_36621751 0.296 NM_018067
MAP7D1
MAP7 domain containing 1
chr18_+_3453771 0.291 NM_173211
TGIF1
TGFB-induced factor homeobox 1
chr18_+_22006605 0.288 NM_018439
IMPACT
Impact homolog (mouse)
chr16_-_89556886 0.285 NM_013275
ANKRD11
ankyrin repeat domain 11
chr12_-_57504088 0.282 NM_001178079
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr3_-_57113292 0.279 NM_001128615
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr16_+_58498725 0.278 NM_022910
NDRG4
NDRG family member 4
chr12_-_51477299 0.265 NM_030809
CSRNP2
cysteine-serine-rich nuclear protein 2
chr15_+_96869156 0.261 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr13_-_33859835 0.259 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr5_-_176981537 0.259 NM_001190946
FAM193B
family with sequence similarity 193, member B
chr18_-_61089695 0.253 NM_004869
VPS4B
vacuolar protein sorting 4 homolog B (S. cerevisiae)
chr1_+_183605207 0.248 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr4_+_174089889 0.243 NM_017423
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr7_-_6312137 0.243 NM_004227
CYTH3
cytohesin 3
chr15_+_100106132 0.243 NM_001130926
NM_001130927
NM_001171894
NM_005587
MEF2A



myocyte enhancer factor 2A



chr22_-_28315214 0.241 NM_012399
PITPNB
phosphatidylinositol transfer protein, beta
chr18_+_3447607 0.241 NM_173207
TGIF1
TGFB-induced factor homeobox 1
chr11_+_129939667 0.240 NM_001142276
NM_001142277
NM_001142278
NM_001642
APLP2



amyloid beta (A4) precursor-like protein 2



chr7_+_18535351 0.240 NM_001204145
NM_001204146
NM_014707
NM_178423
HDAC9



histone deacetylase 9



chr15_+_100173182 0.239 NM_001130928
MEF2A
myocyte enhancer factor 2A
chr21_-_43373938 0.234 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr8_+_79578258 0.232 NM_016010
FAM164A
family with sequence similarity 164, member A
chr4_+_56815036 0.232 NM_025009
CEP135
centrosomal protein 135kDa
chr1_+_170633312 0.228 NM_006902
NM_022716
PRRX1

paired related homeobox 1

chr3_-_52719514 0.227 NM_018313
PBRM1
polybromo 1
chr12_-_102224509 0.227 NM_024312
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr3_+_107241782 0.226 NM_001142568
NM_020235
BBX

bobby sox homolog (Drosophila)

chr3_-_56809594 0.223 NM_001128616
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr17_-_40976264 0.223 NM_003766
BECN1
beclin 1, autophagy related
chr8_-_42397048 0.220 NM_006749
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr16_-_47177902 0.217 NM_001201477
NM_018092
NETO2

neuropilin (NRP) and tolloid (TLL)-like 2

chr13_-_33760215 0.215 NM_001243466
NM_178007
STARD13

StAR-related lipid transfer (START) domain containing 13

chr14_+_75745480 0.215 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chrX_-_3264680 0.214 NM_015419
MXRA5
matrix-remodelling associated 5
chr18_-_53255734 0.214 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr16_-_53737713 0.212 NM_001127897
NM_015272
RPGRIP1L

RPGRIP1-like

chr14_-_82000198 0.212 NM_001244984
NM_005065
SEL1L

sel-1 suppressor of lin-12-like (C. elegans)

chr1_-_21616648 0.207 NM_001113349
ECE1
endothelin converting enzyme 1
chr10_+_11059854 0.205 NM_006561
CELF2
CUGBP, Elav-like family member 2
chr16_+_58497993 0.203 NM_001130487
NDRG4
NDRG family member 4
chr1_+_29213569 0.203 NM_001166005
NM_001166007
NM_004437
NM_203342
NM_203343
EPB41




erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)




chr17_+_2496902 0.200 NM_000430
PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr16_-_84651639 0.200 NM_021149
COTL1
coactosin-like 1 (Dictyostelium)
chr3_-_49449525 0.199 NM_001664
RHOA
ras homolog gene family, member A
chr2_-_217560247 0.198 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr1_-_21671905 0.198 NM_001113348
ECE1
endothelin converting enzyme 1
chr18_+_3412071 0.197 NM_174886
TGIF1
TGFB-induced factor homeobox 1
chr16_+_27561441 0.197 NM_015202
KIAA0556
KIAA0556
chr15_+_92396880 0.196 NM_001145044
NM_013272
SLCO3A1

solute carrier organic anion transporter family, member 3A1

chr1_+_955468 0.194 NM_198576
AGRN
agrin
chr10_+_112257624 0.193 NM_004419
DUSP5
dual specificity phosphatase 5
chr13_-_33780142 0.192 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr3_+_141043054 0.191 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr16_+_58497548 0.190 NM_020465
NDRG4
NDRG family member 4
chr16_+_11762235 0.189 NM_003498
SNN
stannin
chr1_+_220701547 0.189 NM_018650
MARK1
MAP/microtubule affinity-regulating kinase 1
chr7_-_105752974 0.187 NM_006754
SYPL1
synaptophysin-like 1
chr2_-_43453737 0.187 NM_006887
ZFP36L2
zinc finger protein 36, C3H type-like 2
chr18_+_3451589 0.186 NM_170695
NM_173210
TGIF1

TGFB-induced factor homeobox 1

chr4_+_56719808 0.184 NM_001024924
NM_018261
NM_178237
EXOC1


exocyst complex component 1


chr1_+_198125890 0.183 NM_133494
NEK7
NIMA (never in mitosis gene a)-related kinase 7
chr21_+_27107257 0.183 NM_001197297
GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr4_+_56262051 0.183 NM_018475
TMEM165
transmembrane protein 165
chr21_-_36260972 0.180 NM_001001890
NM_001122607
RUNX1

runt-related transcription factor 1

chr11_+_33563772 0.179 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr13_-_50367027 0.179 NM_002267
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr14_+_45431333 0.179 NM_015091
FAM179B
family with sequence similarity 179, member B
chr8_+_26149004 0.178 NM_002717
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr7_-_105752718 0.176 NM_182715
SYPL1
synaptophysin-like 1
chr17_+_36507708 0.174 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr12_+_50135591 0.174 NM_001098576
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr8_-_74884500 0.174 NM_001204857
NM_001204858
NM_001204859
NM_001204860
NM_001204863
NM_001204864
NM_005648
TCEB1






transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)






chr19_-_3700466 0.173 NM_001195733
NM_012398
PIP5K1C

phosphatidylinositol-4-phosphate 5-kinase, type I, gamma

chr18_+_3449972 0.173 NM_173209
NM_173208
NM_003244
TGIF1


TGFB-induced factor homeobox 1



Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
16.70 4.13e-04 GO:0051051 negative regulation of transport
7.41 2.42e-03 GO:0009887 organ morphogenesis
8.40 4.58e-03 GO:0048646 anatomical structure formation involved in morphogenesis
10.54 5.92e-03 GO:0001944 vasculature development
6.04 1.08e-02 GO:0051049 regulation of transport
40.92 1.87e-02 GO:0046888 negative regulation of hormone secretion
174.49 1.89e-02 GO:0060346 bone trabecula formation
17.66 2.55e-02 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
16.19 3.58e-02 GO:0048705 skeletal system morphogenesis
2.77 3.98e-02 GO:0048731 system development
2.42 4.60e-02 GO:0032502 developmental process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.71 3.17e-04 GO:0005886 plasma membrane
2.67 3.97e-04 GO:0071944 cell periphery
124.65 6.81e-03 GO:0005577 fibrinogen complex
2.95 1.60e-02 GO:0044459 plasma membrane part
7.40 3.02e-02 GO:0031012 extracellular matrix
6.74 4.62e-02 GO:0009986 cell surface

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
13.66 1.21e-02 GO:0005539 glycosaminoglycan binding
87.26 1.47e-02 GO:0050431 transforming growth factor beta binding
12.68 1.61e-02 GO:0001871 pattern binding
12.68 1.61e-02 GO:0030247 polysaccharide binding
67.13 2.54e-02 GO:0043394 proteoglycan binding