Motif ID: ACAUUCA

Z-value: 1.189


Mature miRNA associated with seed ACAUUCA:

NamemiRBase Accession
hsa-miR-181a MIMAT0000256
hsa-miR-181b MIMAT0000257
hsa-miR-181c MIMAT0000258
hsa-miR-181d MIMAT0002821
hsa-miR-4262 MIMAT0016894



Activity profile for motif ACAUUCA.

activity profile for motif ACAUUCA


Sorted Z-values histogram for motif ACAUUCA

Sorted Z-values for motif ACAUUCA



Network of associatons between targets according to the STRING database.



First level regulatory network of ACAUUCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_53342320 2.214 NM_002126
HLF
hepatic leukemia factor
chr1_-_92351613 2.130 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr1_-_92371558 1.964 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chr3_+_50304989 1.699 NM_001005914
NM_004636
SEMA3B

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B

chr15_-_61521478 1.681 NM_134261
RORA
RAR-related orphan receptor A
chr16_+_85645014 1.629 NM_001134473
KIAA0182
KIAA0182
chr15_-_60919642 1.566 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr15_-_60884615 1.549 NM_134262
RORA
RAR-related orphan receptor A
chr12_-_8088629 1.456 NM_006931
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr4_+_88896801 1.450 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr16_+_85646923 1.448 NM_014615
KIAA0182
KIAA0182
chr1_-_57045235 1.408 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr7_-_47621741 1.352 NM_022748
TNS3
tensin 3
chr16_+_69599868 1.325 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chrY_+_15016698 1.206 NM_004660
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr19_-_57336373 1.177 NM_001146186
PEG3
paternally expressed 3
chr1_-_169455099 1.160 NM_006996
SLC19A2
solute carrier family 19 (thiamine transporter), member 2
chr5_-_141704575 1.136 NM_001127496
NM_030964
SPRY4

sprouty homolog 4 (Drosophila)

chrX_+_9432980 1.116 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chrY_+_15016018 1.110 NM_001122665
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr3_+_38495778 1.109 NM_001106
ACVR2B
activin A receptor, type IIB
chr6_+_132129154 1.093 NM_006208
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr5_-_121412805 1.082 NM_001178102
LOX
lysyl oxidase
chr5_-_121414011 1.078 NM_002317
LOX
lysyl oxidase
chr2_-_64881040 1.037 NM_014755
SERTAD2
SERTA domain containing 2
chr22_+_33196801 1.031 NM_000362
TIMP3
TIMP metallopeptidase inhibitor 3
chrX_+_9431314 0.992 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr19_-_33793429 0.990 NM_004364
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr5_-_172756505 0.986 NM_003714
STC2
stanniocalcin 2
chrX_-_20284708 0.940 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr6_-_16761600 0.918 NM_000332
NM_001128164
ATXN1

ataxin 1

chr16_-_4166185 0.912 NM_001116
ADCY9
adenylate cyclase 9
chr8_-_57123858 0.907 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr10_+_102732285 0.899 NM_001203244
NM_017893
SEMA4G

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G

chr12_-_56652118 0.881 NM_173595
ANKRD52
ankyrin repeat domain 52
chr20_+_35201948 0.880 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr3_-_129599220 0.855 NM_001017395
TMCC1
transmembrane and coiled-coil domain family 1
chr1_+_169075869 0.822 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr9_-_99329092 0.821 NM_001077181
CDC14B
CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr20_+_35201854 0.811 NM_001199513
NM_001199514
TGIF2

TGFB-induced factor homeobox 2

chr17_-_56494930 0.811 NM_017763
RNF43
ring finger protein 43
chr8_+_26435339 0.789 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr9_-_130742803 0.782 NM_001035254
FAM102A
family with sequence similarity 102, member A
chr18_-_46475702 0.782 NM_001190822
SMAD7
SMAD family member 7
chr1_+_214161859 0.769 NM_002763
PROX1
prospero homeobox 1
chr18_+_55102777 0.768 NM_004852
ONECUT2
one cut homeobox 2
chr16_+_15068832 0.744 NM_015027
PDXDC1
pyridoxal-dependent decarboxylase domain containing 1
chr20_+_60718473 0.738 NM_198935
SS18L1
synovial sarcoma translocation gene on chromosome 18-like 1
chr3_-_129612371 0.729 NM_001128224
TMCC1
transmembrane and coiled-coil domain family 1
chr18_-_46477080 0.725 NM_001190821
NM_005904
SMAD7

SMAD family member 7

chr11_-_93276513 0.724 NM_020179
C11orf75
chromosome 11 open reading frame 75
chr1_+_40627031 0.701 NM_012421
RLF
rearranged L-myc fusion
chr2_-_97535669 0.693 NM_017789
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr13_+_98605928 0.692 NM_002271
IPO5
importin 5
chr8_+_61591239 0.691 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr8_+_26371461 0.689 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr20_+_11871364 0.685 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr9_-_138987096 0.669 NM_144653
NACC2
NACC family member 2, BEN and BTB (POZ) domain containing
chr1_+_28764660 0.669 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr9_-_99382073 0.669 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr2_-_39347562 0.660 NM_005633
SOS1
son of sevenless homolog 1 (Drosophila)
chr20_+_30865435 0.654 NM_004798
KIF3B
kinesin family member 3B
chr3_+_179370779 0.654 NM_003940
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr3_-_195270004 0.626 NM_006241
PPP1R2
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr2_-_69614321 0.618 NM_001244710
NM_002056
GFPT1

glutamine--fructose-6-phosphate transaminase 1

chr22_+_21771661 0.617 NM_015094
HIC2
hypermethylated in cancer 2
chr20_+_30697291 0.616 NM_014742
TM9SF4
transmembrane 9 superfamily protein member 4
chr10_+_114709963 0.614 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr2_+_109065576 0.605 NM_181453
GCC2
GRIP and coiled-coil domain containing 2
chr7_-_156803224 0.604 NM_005515
MNX1
motor neuron and pancreas homeobox 1
chr3_+_23987514 0.598 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr17_-_66287256 0.597 NM_001174166
NM_004694
SLC16A6

solute carrier family 16, member 6 (monocarboxylic acid transporter 7)

chr3_+_63884074 0.597 NM_001177387
ATXN7
ataxin 7
chr4_+_39046198 0.594 NM_001007075
NM_001171654
KLHL5

kelch-like 5 (Drosophila)

chr9_-_130712866 0.592 NM_203305
FAM102A
family with sequence similarity 102, member A
chr17_-_47439326 0.588 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr18_-_46469118 0.588 NM_001190823
SMAD7
SMAD family member 7
chr17_+_73452663 0.587 NM_014738
KIAA0195
KIAA0195
chr12_+_862088 0.582 NM_001184985
NM_014823
NM_018979
NM_213655
WNK1



WNK lysine deficient protein kinase 1



chr6_+_87865261 0.575 NM_015021
ZNF292
zinc finger protein 292
chr22_-_39240016 0.571 NM_014293
NPTXR
neuronal pentraxin receptor
chr20_+_25176333 0.537 NM_001114089
NM_001247
ENTPD6

ectonucleoside triphosphate diphosphohydrolase 6 (putative)

chr9_+_110045516 0.535 NM_002874
RAD23B
RAD23 homolog B (S. cerevisiae)
chr3_+_5021096 0.533 NM_003670
BHLHE40
basic helix-loop-helix family, member e40
chr12_-_24715349 0.531 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr3_+_53195214 0.523 NM_006254
NM_212539
PRKCD

protein kinase C, delta

chr1_+_167298280 0.518 NM_001198783
POU2F1
POU class 2 homeobox 1
chr11_-_46939908 0.506 NM_002334
LRP4
low density lipoprotein receptor-related protein 4
chr3_+_23986735 0.501 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr4_+_1795004 0.501 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr7_+_7222142 0.498 NM_020156
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr3_+_63850181 0.483 NM_000333
ATXN7
ataxin 7
chr1_+_28696056 0.480 NM_001048183
PHACTR4
phosphatase and actin regulator 4
chr4_-_17812093 0.479 NM_017741
DCAF16
DDB1 and CUL4 associated factor 16
chr5_+_75699003 0.479 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr10_-_11653529 0.478 NM_014688
USP6NL
USP6 N-terminal like
chr4_+_38665587 0.477 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr6_-_79787939 0.477 NM_017934
PHIP
pleckstrin homology domain interacting protein
chr7_-_156801980 0.475 NM_001165255
MNX1
motor neuron and pancreas homeobox 1
chr15_+_45879416 0.473 NM_012388
PLDN
pallidin homolog (mouse)
chr20_+_11898536 0.471 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr10_-_735522 0.467 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr12_-_498428 0.467 NM_001042603
KDM5A
lysine (K)-specific demethylase 5A
chr12_-_46766563 0.463 NM_018976
SLC38A2
solute carrier family 38, member 2
chr4_-_174254730 0.461 NM_001130689
HMGB2
high mobility group box 2
chr9_-_4741798 0.460 NM_001199855
AK3
adenylate kinase 3
chr7_-_139477437 0.459 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr1_+_167189948 0.457 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr22_-_39548448 0.454 NM_175709
CBX7
chromobox homolog 7
chr9_-_4741267 0.454 NM_001199852
NM_016282
AK3

adenylate kinase 3

chr2_-_218808705 0.453 NM_022648
TNS1
tensin 1
chr20_+_32077904 0.452 NM_001032999
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr9_-_4726226 0.450 NM_001199856
AK3
adenylate kinase 3
chr8_-_119964059 0.448 NM_002546
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr4_+_39063851 0.448 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr19_-_57352055 0.447 NM_001146326
NM_001146327
NM_015363
NM_001146184
NM_001146185
NM_001146187
NM_006210
ZIM2


PEG3



zinc finger, imprinted 2


paternally expressed 3



chr13_-_39612246 0.442 NM_025138
NM_170719
PROSER1

proline and serine rich 1

chr4_-_174255454 0.441 NM_001130688
NM_002129
HMGB2

high mobility group box 2

chr17_-_36904545 0.434 NM_007144
PCGF2
polycomb group ring finger 2
chr16_-_85045119 0.433 NM_001145548
NM_017740
ZDHHC7

zinc finger, DHHC-type containing 7

chr9_-_4742042 0.430 NM_001199853
AK3
adenylate kinase 3
chr9_-_4741085 0.429 NM_001199854
AK3
adenylate kinase 3
chr12_-_24102563 0.426 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr3_-_69101236 0.420 NM_007114
TMF1
TATA element modulatory factor 1
chr4_-_40631846 0.418 NM_001098634
RBM47
RNA binding motif protein 47
chr2_-_167232464 0.416 NM_002977
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr3_-_48700317 0.413 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr3_-_142166782 0.412 NM_001042604
NM_019001
XRN1

5'-3' exoribonuclease 1

chr20_+_32150139 0.409 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr6_+_34759743 0.409 NM_017754
UHRF1BP1
UHRF1 binding protein 1
chr18_-_12377248 0.408 NM_006796
AFG3L2
AFG3 ATPase family gene 3-like 2 (S. cerevisiae)
chr12_+_70132562 0.407 NM_022456
NM_175624
RAB3IP

RAB3A interacting protein (rabin3)

chr2_-_122406994 0.401 NM_001142273
NM_001142274
NM_001207051
NM_015282
CLASP1



cytoplasmic linker associated protein 1



chr1_+_39456887 0.400 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr20_+_1099216 0.400 NM_006814
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr12_-_23737507 0.397 NM_178010
SOX5
SRY (sex determining region Y)-box 5
chr5_+_82767492 0.397 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr5_-_1524022 0.397 NM_024830
LPCAT1
lysophosphatidylcholine acyltransferase 1
chr15_+_80696569 0.389 NM_014862
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr10_-_11574273 0.385 NM_001080491
USP6NL
USP6 N-terminal like
chr17_+_28707495 0.384 NM_001199775
CPD
carboxypeptidase D
chr4_-_40517913 0.383 NM_019027
RBM47
RNA binding motif protein 47
chr4_+_37892698 0.383 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr1_-_212004113 0.380 NM_014873
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr14_-_95786095 0.378 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr2_+_64681270 0.377 NM_014181
LGALSL
lectin, galactoside-binding-like
chr8_+_21915371 0.376 NM_001114135
EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr3_-_53079285 0.374 NM_001005159
SFMBT1
Scm-like with four mbt domains 1
chr2_-_74692534 0.373 NM_001146158
NM_006302
MOGS

mannosyl-oligosaccharide glucosidase

chr3_-_11761946 0.372 NM_014667
VGLL4
vestigial like 4 (Drosophila)
chr3_-_179169330 0.371 NM_021629
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr8_+_86089618 0.371 NM_001083588
NM_001951
E2F5

E2F transcription factor 5, p130-binding

chr6_-_11044354 0.370 NM_017770
ELOVL2
ELOVL fatty acid elongase 2
chr3_+_171758289 0.370 NM_001135095
FNDC3B
fibronectin type III domain containing 3B
chr8_+_86099909 0.367 NM_001083589
E2F5
E2F transcription factor 5, p130-binding
chr4_+_55095263 0.365 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr9_-_127905715 0.364 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr8_+_21912327 0.363 NM_001114136
NM_001114139
EPB49

erythrocyte membrane protein band 4.9 (dematin)

chr8_+_38034066 0.362 NM_001204878
NM_004874
BAG4

BCL2-associated athanogene 4

chr17_+_28705922 0.360 NM_001304
CPD
carboxypeptidase D
chr10_+_30722856 0.359 NM_001244134
NM_005204
MAP3K8

mitogen-activated protein kinase kinase kinase 8

chr14_+_74111577 0.357 NM_001201366
NM_031427
DNAL1

dynein, axonemal, light chain 1

chr3_-_11623829 0.354 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr3_+_171757413 0.353 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr3_+_63953419 0.352 NM_001128149
ATXN7
ataxin 7
chr1_+_213224530 0.351 NM_001136138
NM_012424
RPS6KC1

ribosomal protein S6 kinase, 52kDa, polypeptide 1

chr2_+_64751436 0.350 NM_001002243
NM_017657
NM_203437
AFTPH


aftiphilin


chr15_+_41952572 0.350 NM_001080541
NM_001164273
MGA

MAX gene associated

chr12_-_12419702 0.349 NM_002336
LRP6
low density lipoprotein receptor-related protein 6
chr16_+_20911556 0.348 NM_020424
LYRM1
LYR motif containing 1
chr10_+_73975752 0.348 NM_001242546
NM_001242547
NM_001242548
NM_173473
ANAPC16



anaphase promoting complex subunit 16



chr3_-_53080038 0.347 NM_001005158
NM_016329
SFMBT1

Scm-like with four mbt domains 1

chr1_+_213031596 0.344 NM_014053
FLVCR1
feline leukemia virus subgroup C cellular receptor 1
chr5_+_137801178 0.340 NM_001964
EGR1
early growth response 1
chr1_+_179923870 0.339 NM_014810
CEP350
centrosomal protein 350kDa
chr7_-_75115536 0.338 NM_001099415
POM121C
POM121 membrane glycoprotein C
chr7_+_99156020 0.334 NM_001083956
NM_001085366
NM_024061
NM_138494
ZNF655



zinc finger protein 655



chr6_+_15246299 0.334 NM_004973
JARID2
jumonji, AT rich interactive domain 2
chr8_-_103136486 0.331 NM_001040624
NM_001040625
NM_001040626
NM_001040627
NM_001040628
NM_001040629
NCALD





neurocalcin delta





chr1_+_182992329 0.326 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr7_+_99156427 0.325 NM_001009958
NM_001009960
NM_001085367
NM_001085368
ZNF655



zinc finger protein 655



chr10_+_89623091 0.320 NM_000314
PTEN
phosphatase and tensin homolog
chr5_+_36876838 0.316 NM_015384
NM_133433
NIPBL

Nipped-B homolog (Drosophila)

chr6_+_10521564 0.311 NM_145649
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr3_-_187463474 0.305 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr10_-_98346793 0.302 NM_020123
TM9SF3
transmembrane 9 superfamily member 3
chr6_+_10555948 0.301 NM_001491
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr11_-_18655962 0.300 NM_194285
SPTY2D1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr8_-_117887045 0.300 NM_006265
RAD21
RAD21 homolog (S. pombe)
chr11_-_118927872 0.299 NM_006389
NM_001130991
HYOU1

hypoxia up-regulated 1

chr10_+_52750904 0.297 NM_001098512
PRKG1
protein kinase, cGMP-dependent, type I
chr11_-_34379526 0.296 NM_145804
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr5_-_142783975 0.294 NM_001018076
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr18_-_55470279 0.294 NM_005603
ATP8B1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr12_+_94542239 0.294 NM_005761
PLXNC1
plexin C1
chr21_-_28339405 0.292 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr2_-_239197091 0.290 NM_022817
PER2
period homolog 2 (Drosophila)
chr13_-_76055872 0.289 NM_014832
TBC1D4
TBC1 domain family, member 4
chr10_+_134351272 0.288 NM_005539
INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
chr19_+_10982244 0.287 NM_199141
CARM1
coactivator-associated arginine methyltransferase 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
109.55 7.63e-03 GO:0051183 vitamin transporter activity
75.33 1.66e-02 GO:0005024 transforming growth factor beta receptor activity
66.97 2.11e-02 GO:0004675 transmembrane receptor protein serine/threonine kinase activity