Motif ID: AGCACCA

Z-value: 2.338


Mature miRNA associated with seed AGCACCA:

NamemiRBase Accession
hsa-miR-29a MIMAT0000086
hsa-miR-29b MIMAT0000100
hsa-miR-29c MIMAT0000681



Activity profile for motif AGCACCA.

activity profile for motif AGCACCA


Sorted Z-values histogram for motif AGCACCA

Sorted Z-values for motif AGCACCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCACCA

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_190044330 7.006 NM_000393
 COL5A2
collagen, type V, alpha 2
chr3_-_120169493 6.592 NM_007085
 FSTL1
follistatin-like 1
chr7_+_94023872 6.580 NM_000089
 COL1A2
collagen, type I, alpha 2
chr5_-_151066492 6.263 NM_003118
 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr3_+_157154579 6.215 NM_002852
 PTX3
pentraxin 3, long
chr2_-_1748285 6.050 NM_012293
 PXDN
peroxidasin homolog (Drosophila)
chr13_-_110959441 5.809 NM_001845
 COL4A1
collagen, type IV, alpha 1
chr2_+_189839078 5.681 NM_000090
 COL3A1
collagen, type III, alpha 1
chr5_-_121412805 5.564 NM_001178102
 LOX
lysyl oxidase
chr9_+_137533643 5.514 NM_000093
 COL5A1
collagen, type V, alpha 1
chr16_+_55515468 5.433 NM_001127891
 MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr14_-_52535945 5.036 NM_007361
 NID2
nidogen 2 (osteonidogen)
chr15_-_48937795 5.024 NM_000138
 FBN1
fibrillin 1
chr12_+_13349601 4.847 NM_001423
 EMP1
epithelial membrane protein 1
chr16_+_55512801 4.836 NM_004530
 MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr3_+_159557649 4.665 NM_001197109
 SCHIP1
schwannomin interacting protein 1
chr3_+_158991035 4.630 NM_001197107
NM_001197108
NM_014575
 SCHIP1


schwannomin interacting protein 1


chr1_-_68299047 4.520 NM_018841
 GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr15_+_81071708 4.397 NM_018689
 KIAA1199
KIAA1199
chr13_+_110959592 4.352 NM_001846
 COL4A2
collagen, type IV, alpha 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 48 entries
Enrichment   P-value GO Accession GO Term
116.05 3.09e-06 GO:0032964 collagen biosynthetic process
116.05 4.37e-02 GO:0008218 bioluminescence
38.69 9.02e-09 GO:0030199 collagen fibril organization
30.95 3.91e-03 GO:0048008 platelet-derived growth factor receptor signaling pathway
30.28 1.88e-05 GO:0043588 skin development
21.50 1.78e-03 GO:0032963 collagen metabolic process
20.02 2.58e-03 GO:0044259 multicellular organismal macromolecule metabolic process
16.59 6.76e-03 GO:0044236 multicellular organismal metabolic process
14.85 9.69e-08 GO:0030198 extracellular matrix organization
10.56 5.00e-04 GO:0031589 cell-substrate adhesion
9.68 9.88e-06 GO:0043062 extracellular structure organization
9.29 2.61e-02 GO:0007160 cell-matrix adhesion
5.14 5.66e-03 GO:0001944 vasculature development
5.01 1.81e-02 GO:0001568 blood vessel development
4.91 3.42e-03 GO:0007411 axon guidance
4.66 9.95e-04 GO:0007409 axonogenesis
4.50 1.53e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
4.44 1.79e-03 GO:0048812 neuron projection morphogenesis
4.30 1.15e-03 GO:0048858 cell projection morphogenesis
4.29 1.18e-03 GO:0000904 cell morphogenesis involved in differentiation

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
Enrichment   P-value GO Accession GO Term
116.05 8.74e-05 GO:0005588 collagen type V
116.05 1.03e-02 GO:0005584 collagen type I
73.85 1.30e-10 GO:0005583 fibrillar collagen
42.20 3.79e-15 GO:0005581 collagen
22.51 7.75e-19 GO:0044420 extracellular matrix part
20.02 7.60e-09 GO:0005604 basement membrane
10.90 1.01e-15 GO:0005578 proteinaceous extracellular matrix
9.03 6.71e-14 GO:0031012 extracellular matrix
6.16 1.98e-02 GO:0005912 adherens junction
5.53 3.84e-02 GO:0070161 anchoring junction
4.03 7.28e-09 GO:0044421 extracellular region part
3.34 1.90e-02 GO:0030054 cell junction
3.15 1.91e-03 GO:0005615 extracellular space
2.86 5.82e-07 GO:0005576 extracellular region
2.01 1.11e-02 GO:0044459 plasma membrane part
1.67 3.10e-02 GO:0005886 plasma membrane
1.64 4.35e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
73.85 1.30e-10 GO:0048407 platelet-derived growth factor binding
23.90 6.06e-14 GO:0005201 extracellular matrix structural constituent
23.22 3.69e-02 GO:0005161 platelet-derived growth factor receptor binding
16.59 1.60e-03 GO:0005518 collagen binding
8.05 3.59e-03 GO:0019838 growth factor binding
3.45 3.82e-03 GO:0005198 structural molecule activity