Motif ID: AGCUUAU

Z-value: 0.586


Mature miRNA associated with seed AGCUUAU:

NamemiRBase Accession
hsa-miR-21 MIMAT0000076
hsa-miR-590-5p MIMAT0003258



Activity profile for motif AGCUUAU.

activity profile for motif AGCUUAU


Sorted Z-values histogram for motif AGCUUAU

Sorted Z-values for motif AGCUUAU



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCUUAU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_33196801 2.047 NM_000362
TIMP3
TIMP metallopeptidase inhibitor 3
chr5_+_135364583 1.794 NM_000358
TGFBI
transforming growth factor, beta-induced, 68kDa
chr5_+_125758818 1.097 NM_001146320
NM_001146321
NM_023927
GRAMD3


GRAM domain containing 3


chr5_+_125800786 0.991 NM_001146322
GRAMD3
GRAM domain containing 3
chr5_+_125695787 0.978 NM_001146319
GRAMD3
GRAM domain containing 3
chr2_+_228678556 0.917 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr11_+_101983170 0.802 NM_001195045
YAP1
Yes-associated protein 1
chr11_-_115375065 0.785 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr11_+_101980736 0.771 NM_001130145
NM_001195044
NM_006106
YAP1


Yes-associated protein 1


chrX_-_131623994 0.738 NM_001170704
MBNL3
muscleblind-like 3 (Drosophila)
chrX_-_131547536 0.668 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr18_-_46475702 0.608 NM_001190822
SMAD7
SMAD family member 7
chrX_-_131573638 0.598 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr13_+_73633097 0.593 NM_001730
KLF5
Kruppel-like factor 5 (intestinal)
chr10_+_124145584 0.583 NM_001195608
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr10_+_124134093 0.555 NM_001001974
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr7_-_139876718 0.534 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr10_+_124151818 0.527 NM_021622
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr1_-_151966713 0.468 NM_002966
S100A10
S100 calcium binding protein A10
chr13_-_80915041 0.445 NM_005842
SPRY2
sprouty homolog 2 (Drosophila)
chr3_+_30647901 0.440 NM_001024847
NM_003242
TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

chr5_+_67584251 0.438 NM_181524
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr20_-_10654429 0.415 NM_000214
JAG1
jagged 1
chr18_-_46477080 0.410 NM_001190821
NM_005904
SMAD7

SMAD family member 7

chr5_+_67588395 0.377 NM_001242466
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr4_-_89744154 0.369 NM_001015045
FAM13A
family with sequence similarity 13, member A
chr16_+_69599868 0.354 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr4_-_89978117 0.349 NM_014883
FAM13A
family with sequence similarity 13, member A
chr5_+_67511578 0.341 NM_181523
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr4_+_124320664 0.322 NM_005841
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr17_+_21191347 0.319 NM_002756
MAP2K3
mitogen-activated protein kinase kinase 3
chr4_+_124317884 0.297 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr5_-_141704575 0.279 NM_001127496
NM_030964
SPRY4

sprouty homolog 4 (Drosophila)

chr2_+_148602569 0.274 NM_001616
ACVR2A
activin A receptor, type IIA
chr1_+_218518675 0.271 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr18_-_46469118 0.261 NM_001190823
SMAD7
SMAD family member 7
chr1_+_154377668 0.256 NM_000565
NM_001206866
NM_181359
IL6R


interleukin 6 receptor


chr4_+_4861371 0.254 NM_002448
MSX1
msh homeobox 1
chr12_-_24715349 0.244 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr17_+_21187967 0.234 NM_145109
MAP2K3
mitogen-activated protein kinase kinase 3
chr8_+_87354958 0.226 NM_007013
WWP1
WW domain containing E3 ubiquitin protein ligase 1
chr9_+_36036900 0.224 NM_021111
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr5_+_67586466 0.220 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr3_+_49506079 0.204 NM_001177643
DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr12_+_53845884 0.200 NM_001098620
NM_001128911
NM_001128912
NM_001128913
NM_001128914
NM_005016
NM_031989
PCBP2






poly(rC) binding protein 2






chr7_-_44924946 0.198 NM_033224
PURB
purine-rich element binding protein B
chr12_-_23737507 0.197 NM_178010
SOX5
SRY (sex determining region Y)-box 5
chr2_+_20646831 0.197 NM_004040
RHOB
ras homolog gene family, member B
chr8_-_119964059 0.197 NM_002546
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr11_-_128894008 0.196 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr22_+_38302085 0.190 NM_033386
MICALL1
MICAL-like 1
chr2_-_48115846 0.181 NM_025133
FBXO11
F-box protein 11
chr13_-_41706587 0.180 NM_152903
KBTBD6
kelch repeat and BTB (POZ) domain containing 6
chr11_-_129062092 0.174 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr3_+_49507470 0.171 NM_001165928
NM_001177634
NM_001177635
NM_001177636
NM_001177637
NM_001177638
NM_001177639
NM_001177640
NM_001177641
NM_001177642
NM_001177644
NM_004393
DAG1











dystroglycan 1 (dystrophin-associated glycoprotein 1)











chr8_+_98881277 0.170 NM_002380
NM_030583
MATN2

matrilin 2

chr4_-_111563278 0.163 NM_001204397
NM_001204398
NM_001204399
NM_153426
NM_153427
PITX2




paired-like homeodomain 2




chr20_+_56884749 0.156 NM_020673
RAB22A
RAB22A, member RAS oncogene family
chrX_-_20284708 0.155 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr10_-_75910525 0.151 NM_012095
NM_207012
AP3M1

adaptor-related protein complex 3, mu 1 subunit

chr1_-_220101925 0.151 NM_018713
SLC30A10
solute carrier family 30, member 10
chr12_-_24102563 0.146 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr14_-_102771469 0.141 NM_014226
MOK
MOK protein kinase
chr6_+_32939371 0.141 NM_001199455
BRD2
bromodomain containing 2
chr16_-_47007567 0.136 NM_005880
DNAJA2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr2_-_218808705 0.133 NM_022648
TNS1
tensin 1
chr11_-_79151694 0.131 NM_001098816
ODZ4
odz, odd Oz/ten-m homolog 4 (Drosophila)
chr16_-_4588379 0.131 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chrX_-_106243442 0.130 NM_001085354
NM_024657
MORC4

MORC family CW-type zinc finger 4

chr1_-_214724974 0.129 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr7_-_30029284 0.127 NM_001145515
NM_014766
NM_001145513
SCRN1


secernin 1


chr11_-_73472057 0.126 NM_001243718
NM_002869
NM_198896
RAB6A


RAB6A, member RAS oncogene family


chr17_+_59477169 0.126 NM_005994
TBX2
T-box 2
chr7_-_30029904 0.125 NM_001145514
SCRN1
secernin 1
chr12_-_76425375 0.122 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr16_-_4588738 0.119 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr15_-_50978983 0.117 NM_017672
TRPM7
transient receptor potential cation channel, subfamily M, member 7
chr8_+_9413439 0.115 NM_003747
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr4_-_102268626 0.110 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr15_-_33360084 0.107 NM_001103184
FMN1
formin 1
chr20_+_62371109 0.107 NM_020062
SLC2A4RG
SLC2A4 regulator
chr11_+_121163501 0.105 NM_001024956
SC5DL
sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like
chr7_+_72349925 0.104 NM_172020
POM121
POM121 membrane glycoprotein
chr2_+_86947387 0.104 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr2_+_70314560 0.102 NM_006196
PCBP1
poly(rC) binding protein 1
chr15_+_59063389 0.102 NM_001040450
NM_001040453
FAM63B

family with sequence similarity 63, member B

chr9_-_34590137 0.099 NM_001207011
CNTFR
ciliary neurotrophic factor receptor
chr4_+_26321307 0.099 NM_005349
NM_203283
RBPJ

recombination signal binding protein for immunoglobulin kappa J region

chr9_-_34589679 0.094 NM_001842
NM_147164
CNTFR

ciliary neurotrophic factor receptor

chr10_-_3827418 0.092 NM_001160124
NM_001160125
NM_001300
KLF6


Kruppel-like factor 6


chr6_-_109330190 0.091 NM_001199934
SESN1
sestrin 1
chr8_-_22550708 0.090 NM_004430
EGR3
early growth response 3
chr6_+_148663728 0.087 NM_015278
SASH1
SAM and SH3 domain containing 1
chr4_-_111544206 0.085 NM_000325
PITX2
paired-like homeodomain 2
chr6_+_32936400 0.085 NM_005104
BRD2
bromodomain containing 2
chr21_-_32931289 0.081 NM_003253
TIAM1
T-cell lymphoma invasion and metastasis 1
chr5_-_141993691 0.081 NM_033137
FGF1
fibroblast growth factor 1 (acidic)
chr20_+_3827421 0.080 NM_001206491
NM_020746
MAVS

mitochondrial antiviral signaling protein

chr2_-_239197091 0.078 NM_022817
PER2
period homolog 2 (Drosophila)
chr15_+_94841429 0.075 NM_001159643
NM_018349
MCTP2

multiple C2 domains, transmembrane 2

chr9_+_115142188 0.073 NM_001195822
NM_032303
HSDL2

hydroxysteroid dehydrogenase like 2

chr12_-_12419702 0.065 NM_002336
LRP6
low density lipoprotein receptor-related protein 6
chr7_-_75115536 0.064 NM_001099415
POM121C
POM121 membrane glycoprotein C
chr6_-_109415514 0.063 NM_014454
SESN1
sestrin 1
chr8_-_9009050 0.062 NM_001201329
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chrX_-_19140581 0.062 NM_001079858
NM_001079859
NM_001079860
NM_001184833
NM_001184834
NM_001184835
NM_001184836
NM_001184837
NM_005756
GPR64








G protein-coupled receptor 64








chr9_-_123476578 0.062 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr8_-_10587942 0.061 NM_031439
SOX7
SRY (sex determining region Y)-box 7
chr8_-_22549901 0.061 NM_001199880
EGR3
early growth response 3
chr8_-_22550057 0.061 NM_001199881
EGR3
early growth response 3
chr6_-_109330752 0.061 NM_001199933
SESN1
sestrin 1
chr6_+_32940860 0.059 NM_001199456
BRD2
bromodomain containing 2
chr4_+_26322184 0.058 NM_015874
NM_203284
RBPJ

recombination signal binding protein for immunoglobulin kappa J region

chr11_+_121163343 0.056 NM_006918
SC5DL
sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like
chr2_+_26987122 0.055 NM_017877
CENPA
C2orf18
centromere protein A
chromosome 2 open reading frame 18
chr12_-_121342050 0.055 NM_139015
SPPL3
signal peptide peptidase-like 3
chr5_-_142077508 0.054 NM_001144934
NM_001144935
FGF1

fibroblast growth factor 1 (acidic)

chr5_-_142065586 0.054 NM_000800
FGF1
fibroblast growth factor 1 (acidic)
chr2_-_132121730 0.054 NM_001077637
WTH3DI
RAB6C-like
chr2_-_48132656 0.053 NM_001190274
FBXO11
F-box protein 11
chr5_-_142000899 0.052 NM_001144892
FGF1
fibroblast growth factor 1 (acidic)
chr18_+_67956136 0.052 NM_004232
SOCS6
suppressor of cytokine signaling 6
chr12_+_5541273 0.052 NM_001102654
NTF3
neurotrophin 3
chr9_+_21802631 0.047 NM_002451
MTAP
methylthioadenosine phosphorylase
chr2_+_130737234 0.046 NM_032144
RAB6C
RAB6C, member RAS oncogene family
chr7_+_11013453 0.046 NM_014660
PHF14
PHD finger protein 14
chr14_+_57046490 0.045 NM_017799
C14orf101
chromosome 14 open reading frame 101
chr1_-_115053758 0.043 NM_015906
NM_033020
TRIM33

tripartite motif containing 33

chr13_+_28712379 0.041 NM_175854
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr6_+_32938658 0.039 NM_001113182
BRD2
bromodomain containing 2
chr3_-_52719514 0.039 NM_018313
PBRM1
polybromo 1
chr2_+_66662516 0.039 NM_002398
MEIS1
Meis homeobox 1
chr10_-_7661613 0.038 NM_032817
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr10_+_112631552 0.037 NM_001199492
NM_014456
NM_145341
PDCD4


programmed cell death 4 (neoplastic transformation inhibitor)


chr9_-_95244750 0.037 NM_001193335
NM_017680
ASPN

asporin

chr1_+_2160133 0.036 NM_003036
SKI
v-ski sarcoma viral oncogene homolog (avian)
chr2_+_166428845 0.036 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr11_+_32851469 0.036 NM_024081
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr20_-_52199635 0.036 NM_006526
ZNF217
zinc finger protein 217
chr4_-_87281374 0.033 NM_138980
NM_138982
MAPK10

mitogen-activated protein kinase 10

chr5_-_142065991 0.033 NM_033136
FGF1
fibroblast growth factor 1 (acidic)
chr5_+_139493689 0.032 NM_005859
PURA
purine-rich element binding protein A
chr5_-_38595506 0.031 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr19_-_58662144 0.031 NM_024620
ZNF329
zinc finger protein 329
chr4_-_87028805 0.031 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr3_+_153839136 0.030 NM_001251963
NM_015595
ARHGEF26

Rho guanine nucleotide exchange factor (GEF) 26

chr15_-_42840992 0.029 NM_153260
LRRC57
leucine rich repeat containing 57
chr12_-_42538432 0.029 NM_001099650
NM_173601
GXYLT1

glucoside xylosyltransferase 1

chr12_+_5603297 0.028 NM_002527
NTF3
neurotrophin 3
chr18_-_33647336 0.026 NM_018170
RPRD1A
regulation of nuclear pre-mRNA domain containing 1A
chr15_-_102030138 0.025 NM_002570
NM_138319
NM_138320
NM_138321
NM_138322
NM_138323
NM_138324
NM_138325
PCSK6







proprotein convertase subtilisin/kexin type 6







chr8_+_61591239 0.025 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr15_+_49715374 0.025 NM_002009
FGF7
fibroblast growth factor 7
chr3_+_10183318 0.024 NM_000551
NM_198156
VHL

von Hippel-Lindau tumor suppressor

chr3_-_16646244 0.024 NM_001190811
DAZL
deleted in azoospermia-like
chr3_-_16646927 0.024 NM_001351
DAZL
deleted in azoospermia-like
chr5_+_86564044 0.022 NM_002890
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr15_+_51200864 0.022 NM_001252127
NM_007347
AP4E1

adaptor-related protein complex 4, epsilon 1 subunit

chr1_-_109825767 0.020 NM_001005290
NM_001032291
NM_032636
PSRC1


proline/serine-rich coiled-coil 1


chr1_+_213123853 0.018 NM_001136474
NM_001136475
NM_024749
VASH2


vasohibin 2


chr4_+_113152838 0.017 NM_001128426
NM_018569
AP1AR

adaptor-related protein complex 1 associated regulatory protein

chr4_+_38665587 0.017 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr11_+_118230292 0.014 NM_001204077
NM_004788
UBE4A

ubiquitination factor E4A

chr2_-_213403280 0.013 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr2_-_201936389 0.012 NM_173822
FAM126B
family with sequence similarity 126, member B
chr2_-_69614321 0.012 NM_001244710
NM_002056
GFPT1

glutamine--fructose-6-phosphate transaminase 1

chr17_-_32690180 0.010 NM_002981
CCL1
chemokine (C-C motif) ligand 1
chrX_+_114524291 0.010 NM_016383
LUZP4
leucine zipper protein 4
chr7_-_92463211 0.009 NM_001259
CDK6
cyclin-dependent kinase 6
chr8_-_101571870 0.009 NM_198401
GAPDHP62
ANKRD46
glyceraldehyde 3 phosphate dehydrogenase pseudogene 62
ankyrin repeat domain 46
chr2_-_43453737 0.009 NM_006887
ZFP36L2
zinc finger protein 36, C3H type-like 2
chr10_-_94003002 0.007 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr14_-_68162419 0.007 NM_001252650
NM_016026
RDH11

retinol dehydrogenase 11 (all-trans/9-cis/11-cis)

chr7_+_138916230 0.005 NM_173569
UBN2
ubinuclein 2
chr1_+_15853348 0.005 NM_015291
DNAJC16
DnaJ (Hsp40) homolog, subfamily C, member 16
chr8_+_42752019 0.005 NM_032410
HOOK3
hook homolog 3 (Drosophila)
chr9_+_132815984 0.002 NM_001136557
NM_001136558
NM_020960
GPR107


G protein-coupled receptor 107


chr15_+_69606741 0.002 NM_001104554
PAQR5
progestin and adipoQ receptor family member V
chr14_-_88789531 0.002 NM_138317
KCNK10
potassium channel, subfamily K, member 10

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
46.16 2.57e-03 GO:0050953 sensory perception of light stimulus

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
34.75 1.52e-03 GO:0005578 proteinaceous extracellular matrix
28.82 2.22e-03 GO:0031012 extracellular matrix
10.41 1.78e-02 GO:0044421 extracellular region part

Nothing significant found in function category.