Motif ID: AIRE.p2

Z-value: 1.162


Transcription factors associated with AIRE.p2:

Gene SymbolEntrez IDGene Name
AIRE 326 autoimmune regulator

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
AIREchr21_+_457101470.185.0e-01Click!


Activity profile for motif AIRE.p2.

activity profile for motif AIRE.p2


Sorted Z-values histogram for motif AIRE.p2

Sorted Z-values for motif AIRE.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AIRE.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_29171729 3.813 NM_000371
TTR
transthyretin
chr4_+_74270832 3.308 ALB
albumin
chr4_-_69886112 3.137 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr10_+_7745341 2.600 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr4_-_84035888 2.558 PLAC8
placenta-specific 8
chr4_+_69681709 2.519 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr10_+_7745354 2.348 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745325 2.247 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745284 2.169 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chrX_-_2882288 2.126 NM_000047
ARSE
arylsulfatase E (chondrodysplasia punctata 1)
chr17_+_41006094 2.014 AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr10_-_101841593 1.996 NM_001308
CPN1
carboxypeptidase N, polypeptide 1
chr5_+_75699003 1.960 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr4_-_84035908 1.777 NM_001130715
NM_016619
PLAC8

placenta-specific 8

chr19_-_39826676 1.706 NM_004877
GMFG
glia maturation factor, gamma
chr17_+_41003184 1.640 NM_003734
AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr4_+_70146216 1.480 NM_001207004
NM_053039
UGT2B28

UDP glucuronosyltransferase 2 family, polypeptide B28

chr19_-_48759141 1.219 NM_001184902
NM_001184904
CARD8

caspase recruitment domain family, member 8

chr16_-_28621279 1.126 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr14_+_95078713 1.095 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
63.30 1.30e-02 GO:0015020 glucuronosyltransferase activity
34.43 4.42e-02 GO:0005507 copper ion binding
17.87 1.42e-04 GO:0004857 enzyme inhibitor activity
16.65 1.97e-02 GO:0061134 peptidase regulator activity
10.23 1.34e-02 GO:0008047 enzyme activator activity
6.54 4.04e-03 GO:0030234 enzyme regulator activity