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• Activity deltas table
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Motif ID: AR.p2

Z-value: 0.997

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr14_-_107131217	7.614		IGHA1	immunoglobulin heavy constant alpha 1
chr14_-_106691698	4.908
chr14_-_106926393	4.884		IGHA1 IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106573348	4.387		IGHV4-31 IGHA1 IGHA2 IGHG1 IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr14_-_107113943	4.230		IGHA1 IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_-_150738232	3.620		CTSS	cathepsin S
chr14_-_106518424	3.134		IGH@ IGHA1 IGHG1 IGHG2 IGHM	immunoglobulin heavy locus immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 2 (G2m marker) immunoglobulin heavy constant mu
chr14_-_106725620	2.522		IGHV4-31 IGHV3-23 IGHA1 IGHG1 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy variable 3-23 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr14_-_106692107	2.504		IGHV4-31 IGHA1 IGHD IGHG1 IGHG3	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_107048697	2.452		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_-_150738255	2.170		CTSS	cathepsin S
chr14_-_106994001	2.084		IGHV3-48 IGH@ IGHA1 IGHM	immunoglobulin heavy variable 3-48 immunoglobulin heavy locus immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant mu
chr14_-_106552313	1.681		IGHA1 IGHD IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_-_150738292	1.454	NM_001199739 NM_004079	CTSS	cathepsin S
chr14_-_107218786	1.206		IGHA1 IGHG1 IGHM	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr16_-_67970734	1.189	NM_002801	PSMB10	proteasome (prosome, macropain) subunit, beta type, 10
chr14_-_107099379	1.011		IGHG1 IGHG3	immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr12_+_113416267	0.904	NM_001032731 NM_002535 NM_016817	OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr1_+_12185955	0.725	NM_152942	TNFRSF8	tumor necrosis factor receptor superfamily, member 8
chr5_-_149792276	0.642		CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr6_-_26235160	0.608	NM_005320	HIST1H1D	histone cluster 1, H1d
chr10_+_70847817	0.580	NM_002727	SRGN	serglycin
chr6_-_6320897	0.560	NM_000129	F13A1	coagulation factor XIII, A1 polypeptide
chr1_-_173174611	0.516		TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr19_+_17638064	0.440		FAM129C	family with sequence similarity 129, member C
chr14_-_106610338	0.435		IGHV4-31 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_-_202129705	0.417		PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr6_-_6320875	0.399		F13A1	coagulation factor XIII, A1 polypeptide
chr4_+_186064416	0.399	NM_001151	SLC25A4	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr14_-_106725232	0.383		ZCWPW2 IGHV3-23 IGKV3-20 IGK@	zinc finger, CW type with PWWP domain 2 immunoglobulin heavy variable 3-23 immunoglobulin kappa variable 3-20 immunoglobulin kappa locus
chr10_-_116444112	0.379		ABLIM1	actin binding LIM protein 1
chr1_+_181003143	0.367		MR1	major histocompatibility complex, class I-related
chr16_-_67970651	0.326		PSMB10	proteasome (prosome, macropain) subunit, beta type, 10
chr18_+_12991329	0.297	NM_032142	CEP192	centrosomal protein 192kDa
chr2_+_135011829	0.296	NM_002410	MGAT5	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr1_-_1149495	0.294	NM_003327	TNFRSF4	tumor necrosis factor receptor superfamily, member 4
chr8_-_7417233	0.288	NM_001136572	FAM90A7	family with sequence similarity 90, member A7
chr8_-_7440174	0.276	NM_001136572	FAM90A7	family with sequence similarity 90, member A7
chr4_+_1953831	0.265		WHSC1	Wolf-Hirschhorn syndrome candidate 1
chr19_+_39899749	0.218
chr14_-_106791054	0.181		IGHV4-31 IGHV3-30 IGHA1 IGHD IGHG1 IGHG2 IGHG3 IGHM SCFV	immunoglobulin heavy variable 4-31 immunoglobulin heavy variable 3-30 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 2 (G2m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu single-chain Fv fragment
chr2_+_231280906	0.181		SP100	SP100 nuclear antigen
chr7_+_20655244	0.170	NM_001163941	ABCB5	ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr1_-_27953046	0.168	NM_001042729	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chrX_+_118602362	0.132	NM_001152	SLC25A5	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr5_+_67588395	0.127	NM_001242466	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr4_+_166128823	0.126		KLHL2	kelch-like 2, Mayven (Drosophila)
chr1_-_156460390	0.103		MEF2D	myocyte enhancer factor 2D
chr7_+_65420507	0.101		VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1
chr18_+_72166568	0.090		CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)
chr11_+_61102035	0.088		DAK	dihydroxyacetone kinase 2 homolog (S. cerevisiae)
chr1_+_104198140	0.082	NM_001008221	AMY1A	amylase, alpha 1A (salivary)
chr1_-_104239071	0.081	NM_001008221	AMY1A	amylase, alpha 1A (salivary)
chr7_+_87563432	0.067	NM_004194 NM_016351 NM_021721 NM_021722 NM_021723	ADAM22	ADAM metallopeptidase domain 22
chr5_-_149324282	0.064	NM_000440	PDE6A	phosphodiesterase 6A, cGMP-specific, rod, alpha
chr1_+_104292278	0.059	NM_001008221	AMY1A	amylase, alpha 1A (salivary)
chr1_-_156785938	0.058	NM_001161443	SH2D2A	SH2 domain containing 2A
chr11_-_113577023	0.048	NM_030770	TMPRSS5	transmembrane protease, serine 5
chr15_+_65914269	0.038	NM_004727	SLC24A1	solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr1_-_156786500	0.037	NM_001161441 NM_001161442 NM_001161444 NM_003975	SH2D2A	SH2 domain containing 2A
chr1_-_159684274	0.036	NM_000567	CRP	C-reactive protein, pentraxin-related
chr20_-_42815732	0.035		JPH2	junctophilin 2
chr12_+_125549924	0.034	NM_023928	AACS	acetoacetyl-CoA synthetase
chr1_+_151129104	0.034	NM_001204848 NM_024575	TNFAIP8L2-SCNM1 TNFAIP8L2	TNFAIP8L2-SCNM1 readthrough tumor necrosis factor, alpha-induced protein 8-like 2
chrX_+_118602391	0.034		SLC25A5	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr12_+_21525801	0.033	NM_000415	IAPP	islet amyloid polypeptide
chr19_+_50472856	0.029		SIGLEC16	sialic acid binding Ig-like lectin 16 (gene/pseudogene)
chrY_-_26194115	0.023	NM_001003894 NM_001003895 NM_004680 NM_170723	CDY1B CDY1	chromodomain protein, Y-linked, 1B chromodomain protein, Y-linked, 1
chr10_-_48806862	0.015	NM_001042357 NM_001042389	PTPN20B PTPN20A	protein tyrosine phosphatase, non-receptor type 20B protein tyrosine phosphatase, non-receptor type 20A
chr11_+_45115563	0.013	NM_020229	PRDM11	PR domain containing 11
chr12_+_125549975	0.011		AACS	acetoacetyl-CoA synthetase
chr15_+_52311432	0.008		MAPK6	mitogen-activated protein kinase 6
chr14_-_106586333	0.007		IGHV4-31	immunoglobulin heavy variable 4-31
chr5_-_150727088	0.005	NM_181776	SLC36A2	solute carrier family 36 (proton/amino acid symporter), member 2
chr19_+_48497907	0.001	NM_022142	ELSPBP1	epididymal sperm binding protein 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
17.80	9.45e-11	GO:0006955	immune response
11.07	7.19e-09	GO:0002376	immune system process
2.57	4.87e-03	GO:0050896	response to stimulus

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
9.01	1.31e-03	GO:0005624	membrane fraction
8.72	1.54e-03	GO:0005626	insoluble fraction
5.42	2.90e-03	GO:0005576	extracellular region
6.61	5.87e-03	GO:0000267	cell fraction

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
221.44	5.50e-16	GO:0003823	antigen binding