Motif ID: ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Z-value: 2.722


Transcription factors associated with ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2:

Gene SymbolEntrez IDGene Name
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2
BHLHB2 8553 basic helix-loop-helix domain containing, class B, 2
MAX 4149 MYC associated factor X
MYC 4609 v-myc myelocytomatosis viral oncogene homolog (avian)
USF1 7391 upstream transcription factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MAXchr14_-_655692210.792.8e-04Click!
MYCchr8_+_1287484760.621.1e-02Click!
ARNTchr1_-_1508492110.562.6e-02Click!
ARNT2chr15_+_80696569-0.401.2e-01Click!
BHLHE40chr3_+_5021141-0.381.4e-01Click!


Activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2.

activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2


Sorted Z-values histogram for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Sorted Z-values for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_58146108 9.653 CDK4
cyclin-dependent kinase 4
chr11_+_67159421 9.428 NM_004584
 RAD9A
RAD9 homolog A (S. pombe)
chr12_-_58146025 9.264 CDK4
cyclin-dependent kinase 4
chr12_-_58146110 8.482 CDK4
cyclin-dependent kinase 4
chr12_-_58146118 8.171 NM_000075
 CDK4
cyclin-dependent kinase 4
chr16_+_2570322 7.591 NM_001145815
NM_015944
 AMDHD2

amidohydrolase domain containing 2

chr1_-_26232890 6.920 NM_001145454
NM_005563
 STMN1

stathmin 1

chr4_-_103266577 6.908 NM_001135146
 SLC39A8
solute carrier family 39 (zinc transporter), member 8
chrX_+_102470003 6.885 NM_001080425
NM_001127688
 BEX4

brain expressed, X-linked 4

chrX_-_100603956 6.486 NM_004085
 TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr14_-_20923266 5.826 NM_017807
 OSGEP
O-sialoglycoprotein endopeptidase
chr6_-_43197178 5.799 NM_006443
NM_199184
 C6orf108

chromosome 6 open reading frame 108

chr1_+_44440642 5.706 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr11_-_85780088 5.681 PICALM
phosphatidylinositol binding clathrin assembly protein
chr11_-_85780105 5.662 NM_001008660
NM_001206946
NM_007166
 PICALM


phosphatidylinositol binding clathrin assembly protein


chr7_+_150759633 5.661 NM_001199693
NM_001199694
 SLC4A2

solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)

chr1_+_44440673 5.253 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr3_+_113465901 5.176 ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr7_+_106685007 5.141 NM_002736
 PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr6_-_31763415 5.116 VARS
valyl-tRNA synthetase

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
Enrichment   P-value GO Accession GO Term
5.71 2.63e-02 GO:0018205 peptidyl-lysine modification
4.00 4.63e-02 GO:0006417 regulation of translation
2.42 3.81e-02 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
2.41 2.09e-02 GO:0006396 RNA processing
2.30 3.41e-02 GO:0046483 heterocycle metabolic process
1.84 8.02e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.79 2.04e-07 GO:0034641 cellular nitrogen compound metabolic process
1.77 8.85e-03 GO:0044281 small molecule metabolic process
1.73 1.26e-06 GO:0006807 nitrogen compound metabolic process
1.71 3.61e-03 GO:0090304 nucleic acid metabolic process
1.36 6.61e-04 GO:0044237 cellular metabolic process
1.31 1.08e-02 GO:0044238 primary metabolic process
1.27 2.25e-02 GO:0008152 metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 24 entries
Enrichment   P-value GO Accession GO Term
22.51 4.27e-02 GO:0042719 mitochondrial intermembrane space protein transporter complex
7.11 3.48e-02 GO:0016469 proton-transporting two-sector ATPase complex
3.34 6.14e-07 GO:0005730 nucleolus
3.05 3.08e-03 GO:0019866 organelle inner membrane
2.97 1.21e-02 GO:0005743 mitochondrial inner membrane
2.50 2.97e-04 GO:0031967 organelle envelope
2.46 4.14e-04 GO:0031975 envelope
2.07 2.52e-07 GO:0031981 nuclear lumen
1.99 8.96e-08 GO:0044428 nuclear part
1.88 7.04e-07 GO:0031974 membrane-enclosed lumen
1.86 3.32e-06 GO:0070013 intracellular organelle lumen
1.85 3.90e-06 GO:0043233 organelle lumen
1.79 1.71e-02 GO:0005654 nucleoplasm
1.52 5.77e-08 GO:0044446 intracellular organelle part
1.51 7.99e-08 GO:0044422 organelle part
1.45 1.20e-02 GO:0032991 macromolecular complex
1.41 1.09e-04 GO:0005634 nucleus
1.31 5.57e-07 GO:0043227 membrane-bounded organelle
1.30 1.04e-06 GO:0043231 intracellular membrane-bounded organelle
1.26 3.11e-06 GO:0043226 organelle

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
10.39 4.32e-03 GO:0003727 single-stranded RNA binding
2.24 2.36e-03 GO:0003723 RNA binding