Motif ID: ATF5_CREB3.p2

Z-value: 1.471


Transcription factors associated with ATF5_CREB3.p2:

Gene SymbolEntrez IDGene Name
ATF5 22809 activating transcription factor 5
CREB3 10488 cAMP responsive element binding protein 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CREB3chr9_+_35732498-0.341.9e-01Click!
ATF5chr19_+_504323990.136.4e-01Click!


Activity profile for motif ATF5_CREB3.p2.

activity profile for motif ATF5_CREB3.p2


Sorted Z-values histogram for motif ATF5_CREB3.p2

Sorted Z-values for motif ATF5_CREB3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF5_CREB3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_75310852 2.997 NM_001657
AREG
amphiregulin
chr4_+_75480628 2.953 NM_001657
AREG
amphiregulin
chr14_+_68086633 2.219 ARG2
arginase, type II
chr4_+_85504056 1.627 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr1_+_156030965 1.580 NM_020387
RAB25
RAB25, member RAS oncogene family
chr8_-_22550708 1.495 NM_004430
EGR3
early growth response 3
chr5_-_1882764 1.475 NM_016358
IRX4
iroquois homeobox 4
chr20_-_56284945 1.359 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr17_-_39780762 1.357 NM_000422
KRT17
keratin 17
chr12_+_4382882 1.344 NM_001759
CCND2
cyclin D2
chr18_+_20513277 1.301 NM_002894
RBBP8
retinoblastoma binding protein 8
chr1_+_26496382 1.244 NM_015871
ZNF593
zinc finger protein 593
chr3_-_33759684 1.209 NM_015097
CLASP2
cytoplasmic linker associated protein 2
chr3_+_185303961 1.205 NM_021627
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr2_+_75061234 1.168 HK2
hexokinase 2
chr2_-_60780404 1.136 NM_018014
NM_022893
NM_138559
BCL11A


B-cell CLL/lymphoma 11A (zinc finger protein)


chr7_+_116660263 1.088 ST7
suppression of tumorigenicity 7
chr12_+_132629014 1.079 NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr1_-_185286210 1.067 IVNS1ABP
influenza virus NS1A binding protein
chr2_-_60780767 1.064 BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr4_-_56502358 1.057 NM_006681
NMU
neuromedin U
chr5_+_137801166 1.047 EGR1
early growth response 1
chr1_-_185286460 1.039 NM_006469
IVNS1ABP
influenza virus NS1A binding protein
chr12_+_132628978 1.018 NM_024078
NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr3_-_33759540 1.014 CLASP2
cytoplasmic linker associated protein 2
chr14_+_68086655 1.005 ARG2
arginase, type II
chr7_+_5632435 1.000 NM_003088
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr10_+_35484829 0.992 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr1_+_233749749 0.990 NM_002245
KCNK1
potassium channel, subfamily K, member 1
chr21_-_34915124 0.978 NM_001136005
NM_001136006
GART

phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase

chr12_-_123380682 0.965 NM_024667
VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr6_+_30294224 0.945


chrX_-_78622711 0.896 ITM2A
integral membrane protein 2A
chr7_-_140624280 0.890 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr10_+_103911932 0.868 NM_004741
NOLC1
nucleolar and coiled-body phosphoprotein 1
chr8_+_61591239 0.868 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr12_-_123380628 0.866 VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr8_-_131028833 0.861 FAM49B
family with sequence similarity 49, member B
chr3_+_158288952 0.860 NM_001130156
NM_001130157
NM_001195432
NM_001195433
NM_001195434
NM_022443
MLF1





myeloid leukemia factor 1





chr1_-_209979388 0.825 NM_001206696
NM_006147
IRF6

interferon regulatory factor 6

chr1_-_150602041 0.825 ENSA
endosulfine alpha
chr5_-_138211054 0.814 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr17_-_8151373 0.810 NM_025099
CTC1
CTS telomere maintenance complex component 1
chr19_-_43969723 0.803 NM_014400
LYPD3
LY6/PLAUR domain containing 3
chr19_+_4402658 0.800 NM_005483
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr8_-_102803178 0.788 NCALD
neurocalcin delta
chr3_+_193853930 0.783 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr8_-_102803196 0.760 NCALD
neurocalcin delta
chr22_+_26879812 0.731 NM_001013694
SRRD
SRR1 domain containing
chr3_+_193853937 0.728 HES1
hairy and enhancer of split 1, (Drosophila)
chr8_-_110661007 0.724 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr8_-_131028674 0.720 FAM49B
family with sequence similarity 49, member B
chr1_+_116916029 0.716 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr18_+_57567191 0.715 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr1_+_242011544 0.709 EXO1
exonuclease 1
chr1_+_52082755 0.709 OSBPL9
oxysterol binding protein-like 9
chr19_+_10362886 0.708 MRPL4
mitochondrial ribosomal protein L4
chr1_+_242011471 0.708 NM_130398
EXO1
exonuclease 1
chr17_-_685385 0.704 NM_016080
GLOD4
glyoxalase domain containing 4
chr1_+_233749917 0.699 KCNK1
potassium channel, subfamily K, member 1
chr11_+_3818953 0.697 NM_001145438
PGAP2
post-GPI attachment to proteins 2
chr2_+_172821874 0.688 HAT1
histone acetyltransferase 1
chr11_+_66610882 0.687 NM_001032279
NM_005133
RCE1

RCE1 homolog, prenyl protein protease (S. cerevisiae)

chr1_-_47184790 0.685


chr1_-_53704121 0.678 NM_002370
MAGOH
mago-nashi homolog, proliferation-associated (Drosophila)
chr21_-_43187265 0.671 RIPK4
receptor-interacting serine-threonine kinase 4
chrX_+_24167728 0.670 NM_001178086
NM_001178095
NM_001178084
NM_001178085
NM_003410
ZFX




zinc finger protein, X-linked




chr14_-_55369163 0.668 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr6_+_28048481 0.665 NM_003447
ZNF165
zinc finger protein 165
chr8_-_29207795 0.664 NM_001394
DUSP4
dual specificity phosphatase 4
chr6_-_31774579 0.664 LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr21_-_44846927 0.661 NM_173354
SIK1
salt-inducible kinase 1
chr1_-_202927439 0.661 ADIPOR1
adiponectin receptor 1
chr6_+_44214786 0.661 NM_007355
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr21_-_43187197 0.658 NM_020639
RIPK4
receptor-interacting serine-threonine kinase 4
chr1_-_202927410 0.656 ADIPOR1
adiponectin receptor 1
chr5_-_138210992 0.649 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr3_-_150480887 0.648 SIAH2
seven in absentia homolog 2 (Drosophila)
chr1_+_116915938 0.646 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr8_-_81083660 0.645 NM_001025253
NM_005079
TPD52

tumor protein D52

chr12_-_31479120 0.643 NM_001135811
NM_021238
NM_001135812
FAM60A


family with sequence similarity 60, member A


chr1_-_202927269 0.641 ADIPOR1
adiponectin receptor 1
chr16_-_67694602 0.637 NM_001082486
NM_001082487
NM_022914
ACD


adrenocortical dysplasia homolog (mouse)


chr4_-_122744782 0.635 CCNA2
cyclin A2
chr15_+_31619043 0.634 NM_015995
KLF13
Kruppel-like factor 13
chr6_-_31774725 0.632 NM_021177
LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_+_40627066 0.629 RLF
rearranged L-myc fusion
chr14_-_23388359 0.628 RBM23
RNA binding motif protein 23
chr2_+_74757243 0.623 HTRA2
HtrA serine peptidase 2
chr5_-_175964223 0.616 NM_014901
RNF44
ring finger protein 44
chr1_+_116915881 0.610 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr14_-_23388380 0.606 NM_001077351
NM_001077352
NM_018107
RBM23


RNA binding motif protein 23


chr16_-_3767449 0.605 NM_016292
TRAP1
TNF receptor-associated protein 1
chr1_-_1284755 0.602 DVL1
dishevelled, dsh homolog 1 (Drosophila)
chr17_-_46703613 0.599 NM_024017
HOXB9
homeobox B9
chr2_-_24149899 0.598 NM_001242338
NM_017552
ATAD2B

ATPase family, AAA domain containing 2B

chr11_-_3818736 0.596 NUP98
nucleoporin 98kDa
chr3_+_45017729 0.595 NM_015004
EXOSC7
exosome component 7
chr2_+_118572283 0.594 DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr22_+_21771661 0.593 NM_015094
HIC2
hypermethylated in cancer 2
chr3_-_33700932 0.591 NM_001207044
CLASP2
cytoplasmic linker associated protein 2
chr11_+_4116077 0.590 RRM1
ribonucleotide reductase M1
chr2_-_73520448 0.589 NM_001965
EGR4
early growth response 4
chr4_+_39460643 0.587 NM_006859
NM_194451
LIAS

lipoic acid synthetase

chr14_-_23388294 0.587 RBM23
RNA binding motif protein 23
chr3_+_45017749 0.586 EXOSC7
exosome component 7
chr16_-_20911560 0.581 NM_173475
DCUN1D3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr2_+_231577536 0.580 NM_016289
CAB39
calcium binding protein 39
chr1_+_40627031 0.578 NM_012421
RLF
rearranged L-myc fusion
chr7_+_155089614 0.573 INSIG1
insulin induced gene 1
chr8_-_80993009 0.572 NM_001025252
TPD52
tumor protein D52
chr1_-_156786500 0.571 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr5_+_137801178 0.566 NM_001964
EGR1
early growth response 1
chr1_-_38273823 0.556 YRDC
yrdC domain containing (E. coli)
chr1_+_39456887 0.554 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr5_+_50678957 0.554 NM_002202
ISL1
ISL LIM homeobox 1
chr3_-_195808958 0.554 NM_003234
TFRC
transferrin receptor (p90, CD71)
chrX_-_138287180 0.554 NM_001139498
NM_001139500
NM_001139501
FGF13


fibroblast growth factor 13


chr15_+_66679107 0.546 NM_002755
MAP2K1
mitogen-activated protein kinase kinase 1
chr2_-_10588273 0.542 ODC1
ornithine decarboxylase 1
chr4_+_175204827 0.542 NM_001040157
CEP44
centrosomal protein 44kDa
chr14_-_67878859 0.541 PLEK2
pleckstrin 2
chr16_+_68057144 0.541 NM_017803
DUS2L
dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae)
chr1_-_38273852 0.541 NM_024640
YRDC
yrdC domain containing (E. coli)
chr1_+_116915794 0.541 NM_000701
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr6_+_44214853 0.540 HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr10_-_64576123 0.540 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr10_+_112257624 0.539 NM_004419
DUSP5
dual specificity phosphatase 5
chr12_-_132628841 0.535 NM_175066
DDX51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr3_-_195808997 0.533 NM_001128148
TFRC
transferrin receptor (p90, CD71)
chr7_+_155089483 0.532 NM_005542
NM_198336
NM_198337
INSIG1


insulin induced gene 1


chr5_-_43313492 0.531 HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr2_+_118572284 0.531 DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr11_-_3818706 0.530 NUP98
nucleoporin 98kDa
chr1_-_38273846 0.528 YRDC
yrdC domain containing (E. coli)
chr12_-_14956315 0.525 WBP11
WW domain binding protein 11
chr3_-_150480917 0.522 SIAH2
seven in absentia homolog 2 (Drosophila)
chrX_-_100662905 0.522 NM_000169
GLA
galactosidase, alpha
chr3_-_12800739 0.521 NM_018306
TMEM40
transmembrane protein 40
chr20_+_18488167 0.519 NM_006363
NM_032985
NM_032986
NM_001172746
SEC23B



Sec23 homolog B (S. cerevisiae)



chr5_+_44808967 0.517 NM_016640
MRPS30
mitochondrial ribosomal protein S30
chr14_+_68086570 0.516 NM_001172
ARG2
arginase, type II
chr5_-_16617085 0.515 NM_001034850
FAM134B
family with sequence similarity 134, member B
chr5_-_43313581 0.514 NM_001098272
NM_002130
HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr19_+_1941184 0.513 CSNK1G2
casein kinase 1, gamma 2
chr10_+_13203547 0.512 NM_018518
NM_182751
MCM10

minichromosome maintenance complex component 10

chr11_+_18416111 0.510 LDHA
lactate dehydrogenase A
chr17_-_8151353 0.510 CTC1
CTS telomere maintenance complex component 1
chr6_+_106959729 0.509 NM_001624
AIM1
absent in melanoma 1
chr2_-_27531113 0.507 NM_003353
UCN
urocortin
chr6_-_26285726 0.507 NM_003543
HIST1H4H
histone cluster 1, H4h
chr6_+_138188352 0.506 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr12_-_31479038 0.504 FAM60A
family with sequence similarity 60, member A
chr12_-_31479084 0.502 FAM60A
family with sequence similarity 60, member A
chr11_+_18416106 0.501 LDHA
lactate dehydrogenase A
chr19_-_9731883 0.499 NM_152289
ZNF561
zinc finger protein 561
chr2_+_118572254 0.498 NM_006773
DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr22_+_21996572 0.498 SDF2L1
stromal cell-derived factor 2-like 1
chr5_-_95297597 0.494 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chrX_-_13835213 0.494 GPM6B
glycoprotein M6B
chr7_+_5632453 0.492 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr8_-_17104266 0.490 NM_013354
NM_054026
CNOT7

CCR4-NOT transcription complex, subunit 7

chr16_-_67694110 0.490 ACD
adrenocortical dysplasia homolog (mouse)
chr22_+_21996591 0.489 SDF2L1
stromal cell-derived factor 2-like 1
chr7_+_16793320 0.487 NM_014399
TSPAN13
tetraspanin 13
chrX_-_100662788 0.485 GLA
galactosidase, alpha
chr5_+_68389916 0.485 SLC30A5
solute carrier family 30 (zinc transporter), member 5
chr7_-_45151272 0.485 TBRG4
transforming growth factor beta regulator 4
chr4_-_68566847 0.482 NM_018227
UBA6
ubiquitin-like modifier activating enzyme 6
chr20_+_35201948 0.481 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr6_-_34664587 0.477 NM_022758
NM_024294
C6orf106

chromosome 6 open reading frame 106

chr3_-_45017600 0.476 NM_001135179
NM_016598
ZDHHC3

zinc finger, DHHC-type containing 3

chr1_+_212208918 0.475 NM_016448
DTL
denticleless homolog (Drosophila)
chr1_+_198608216 0.475 PTPRC
protein tyrosine phosphatase, receptor type, C
chr2_-_160472960 0.474 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chrX_+_44732402 0.472 NM_021140
KDM6A
lysine (K)-specific demethylase 6A
chr8_-_17104103 0.469 CNOT7
CCR4-NOT transcription complex, subunit 7
chr10_+_119000583 0.468 NM_003054
SLC18A2
solute carrier family 18 (vesicular monoamine), member 2
chr2_-_10588451 0.467 NM_002539
ODC1
ornithine decarboxylase 1
chr4_-_122744978 0.467 NM_001237
CCNA2
cyclin A2
chr22_-_26879724 0.467 HPS4
Hermansky-Pudlak syndrome 4
chr1_-_202927460 0.466 NM_015999
ADIPOR1
adiponectin receptor 1
chr12_-_14956408 0.464 WBP11
WW domain binding protein 11
chr8_+_86089618 0.463 NM_001083588
NM_001951
E2F5

E2F transcription factor 5, p130-binding

chr11_-_118972529 0.463 DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr11_+_4115923 0.461 NM_001033
RRM1
ribonucleotide reductase M1
chr3_+_128598471 0.461 ACAD9
acyl-CoA dehydrogenase family, member 9
chr1_+_2005083 0.458 NM_001033581
PRKCZ
protein kinase C, zeta
chr11_+_4116059 0.458 RRM1
ribonucleotide reductase M1
chr19_-_47220296 0.457 NM_001079880
NM_001079881
NM_016457
PRKD2


protein kinase D2


chr16_+_54965110 0.457 NM_001252197
NM_005853
IRX5

iroquois homeobox 5

chr3_-_185655833 0.456 NM_001243879
NM_004593
TRA2B

transformer 2 beta homolog (Drosophila)

chr11_+_118955569 0.455 NM_000190
HMBS
hydroxymethylbilane synthase
chrX_+_24167861 0.455 ZFX
zinc finger protein, X-linked
chr3_-_195808934 0.455 TFRC
transferrin receptor (p90, CD71)
chr2_+_105953815 0.454 C2orf49
chromosome 2 open reading frame 49
chr17_+_685606 0.453 RNMTL1
RNA methyltransferase like 1
chr20_+_17207596 0.453 NM_001201529
NM_002594
PCSK2

proprotein convertase subtilisin/kexin type 2

chr1_+_45205558 0.449 KIF2C
kinesin family member 2C
chr7_-_25164902 0.448 NM_018947
CYCS
cytochrome c, somatic

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.