Motif ID: ATF6.p2

Z-value: 1.901


Transcription factors associated with ATF6.p2:

Gene SymbolEntrez IDGene Name
ATF6 22926 activating transcription factor 6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ATF6chr1_+_1617360330.411.1e-01Click!


Activity profile for motif ATF6.p2.

activity profile for motif ATF6.p2


Sorted Z-values histogram for motif ATF6.p2

Sorted Z-values for motif ATF6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF6.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_100914816 5.464 NM_014782
NM_177949
ARMCX2

armadillo repeat containing, X-linked 2

chr7_+_94024201 5.287 COL1A2
collagen, type I, alpha 2
chr7_+_94023872 3.664 NM_000089
COL1A2
collagen, type I, alpha 2
chr6_+_151561094 3.169 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr17_-_46688362 3.122 NM_004502
HOXB7
homeobox B7
chr19_+_16187266 3.011 TPM4
tropomyosin 4
chr17_-_46687925 2.990 HOXB7
homeobox B7
chr19_+_50031232 2.979 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr19_+_16187315 2.845 TPM4
tropomyosin 4
chr19_+_16187306 2.507 TPM4
tropomyosin 4
chr1_+_183605207 2.378 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr11_-_35547144 2.370 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr19_+_49458031 2.191 NM_004324
NM_138761
NM_138763
NM_138764
BAX



BCL2-associated X protein



chr12_-_106641675 2.179 NM_006825
CKAP4
cytoskeleton-associated protein 4
chrX_+_100805415 2.154 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr19_+_49458151 2.038 BAX
BCL2-associated X protein
chr19_+_49458129 1.997 BAX
BCL2-associated X protein
chr8_+_26240522 1.987 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr3_-_49395697 1.940 GPX1
glutathione peroxidase 1
chr5_+_102201713 1.924 PAM
peptidylglycine alpha-amidating monooxygenase
chr11_+_32112414 1.923 NM_002901
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr22_+_35777051 1.898 NM_002133
HMOX1
heme oxygenase (decycling) 1
chr3_-_49395751 1.892 NM_000581
NM_201397
GPX1

glutathione peroxidase 1

chr22_+_35777087 1.818 HMOX1
heme oxygenase (decycling) 1
chr7_+_128470462 1.807 NM_001127487
NM_001458
FLNC

filamin C, gamma

chr19_+_16187047 1.790 NM_003290
TPM4
tropomyosin 4
chr14_+_45431333 1.732 NM_015091
FAM179B
family with sequence similarity 179, member B
chr17_-_46688279 1.708 HOXB7
homeobox B7
chr3_-_73673978 1.706 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr2_+_30454396 1.646 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr10_-_62703822 1.624 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr3_+_158519888 1.609 MFSD1
major facilitator superfamily domain containing 1
chr2_-_1748285 1.603 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr5_+_102201526 1.581 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr2_+_28615695 1.539 FOSL2
FOS-like antigen 2
chr22_+_38864015 1.509 NM_006855
NM_016657
KDELR3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

chr1_-_193155723 1.503 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr3_+_158519911 1.493 MFSD1
major facilitator superfamily domain containing 1
chr12_-_49318663 1.483 NM_001143781
FKBP11
FK506 binding protein 11, 19 kDa
chr3_-_57583090 1.462 ARF4
ADP-ribosylation factor 4
chr3_-_57583153 1.438 NM_001660
ARF4
ADP-ribosylation factor 4
chr2_+_46926049 1.400 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr12_+_56109851 1.393 BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr11_+_69455938 1.385 CCND1
cyclin D1
chr11_+_32112607 1.354 RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr8_-_95274540 1.343 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr7_-_19157262 1.338 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr2_+_46926323 1.331 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr11_+_69455837 1.317 NM_053056
CCND1
cyclin D1
chr9_-_79520878 1.295 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr5_-_172198160 1.285 NM_004417
DUSP1
dual specificity phosphatase 1
chr3_+_8543508 1.264 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr4_-_186456580 1.257 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr1_+_150122095 1.245 NM_016274
PLEKHO1
pleckstrin homology domain containing, family O member 1
chr7_-_129592794 1.225 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H

chr10_-_128077072 1.225 NM_003474
NM_021641
ADAM12

ADAM metallopeptidase domain 12

chr3_+_154798078 1.220 NM_007289
MME
membrane metallo-endopeptidase
chr3_-_57582866 1.215 ARF4
ADP-ribosylation factor 4
chr8_-_13134028 1.197 DLC1
deleted in liver cancer 1
chrX_+_47441802 1.182 TIMP1
TIMP metallopeptidase inhibitor 1
chr4_-_119757288 1.166 NM_014822
SEC24D
SEC24 family, member D (S. cerevisiae)
chr9_+_137533643 1.160 NM_000093
COL5A1
collagen, type V, alpha 1
chr4_-_119757183 1.157 SEC24D
SEC24 family, member D (S. cerevisiae)
chr3_+_158519714 1.154 NM_001167903
NM_022736
MFSD1

major facilitator superfamily domain containing 1

chr3_+_171757432 1.153 FNDC3B
fibronectin type III domain containing 3B
chr2_+_30369749 1.144 NM_001127399
NM_001127400
NM_001127401
NM_016061
YPEL5



yippee-like 5 (Drosophila)



chr10_+_70847817 1.131 NM_002727
SRGN
serglycin
chr1_+_183774214 1.122 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr3_+_50284325 1.105 NM_001166425
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr3_+_158519877 1.104 MFSD1
major facilitator superfamily domain containing 1
chr3_+_100211554 1.094 TMEM45A
transmembrane protein 45A
chr12_+_56109832 1.071 BLOC1S1-RDH5
BLOC1S1
BLOC1S1-RDH5 readthrough
biogenesis of lysosomal organelles complex-1, subunit 1
chr3_-_139108511 1.067 NM_004766
COPB2
coatomer protein complex, subunit beta 2 (beta prime)
chrX_+_47441650 1.063 NM_003254
TIMP1
TIMP metallopeptidase inhibitor 1
chr7_-_129592711 1.052 NM_001202498
UBE2H
ubiquitin-conjugating enzyme E2H
chr14_+_93260630 1.050 NM_005113
GOLGA5
golgin A5
chr14_+_101292451 1.044 MEG3
maternally expressed 3 (non-protein coding)
chr20_+_19915716 1.036 RIN2
Ras and Rab interactor 2
chrX_-_100872926 1.030 NM_001009584
NM_001184768
NM_019007
ARMCX6


armadillo repeat containing, X-linked 6


chr3_-_99594915 1.022 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr2_+_30369800 1.019 YPEL5
yippee-like 5 (Drosophila)
chr3_+_100211408 1.018 NM_018004
TMEM45A
transmembrane protein 45A
chr12_+_56552141 1.016 MYL6
myosin, light chain 6, alkali, smooth muscle and non-muscle
chr16_+_84328400 1.013 NM_021197
WFDC1
WAP four-disulfide core domain 1
chr8_-_95274520 1.013 GEM
GTP binding protein overexpressed in skeletal muscle
chr1_-_241520384 1.008 RGS7
regulator of G-protein signaling 7
chr1_-_203154304 0.999 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr3_-_127541160 0.994 NM_007283
MGLL
monoglyceride lipase
chr3_-_139108421 0.993 COPB2
coatomer protein complex, subunit beta 2 (beta prime)
chr6_+_114178516 0.989 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr3_-_187463474 0.981 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr21_+_38445562 0.973 NM_001001894
TTC3
tetratricopeptide repeat domain 3
chrX_-_34675366 0.969 NM_031442
TMEM47
transmembrane protein 47
chr14_+_101292483 0.968


chr1_-_241520467 0.966 NM_002924
RGS7
regulator of G-protein signaling 7
chr2_-_216300770 0.965 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr3_+_23987514 0.962 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr11_-_9286832 0.959 NM_001243254
NM_015213
DENND5A

DENN/MADD domain containing 5A

chrX_-_48931645 0.948 NM_007213
PRAF2
PRA1 domain family, member 2
chr18_+_72922725 0.946 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr13_+_113951589 0.917 LAMP1
lysosomal-associated membrane protein 1
chr6_-_90062439 0.917 UBE2J1
ubiquitin-conjugating enzyme E2, J1, U
chr2_+_30369868 0.911 YPEL5
yippee-like 5 (Drosophila)
chr13_+_113951537 0.892 LAMP1
lysosomal-associated membrane protein 1
chr12_+_56109817 0.892 NM_001487
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr14_+_74486049 0.889 NM_025057
C14orf45
chromosome 14 open reading frame 45
chr11_+_46299161 0.867 NM_052854
CREB3L1
cAMP responsive element binding protein 3-like 1
chrX_-_15873094 0.861 NM_003916
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr18_+_7567313 0.845 NM_001105244
NM_002845
PTPRM

protein tyrosine phosphatase, receptor type, M

chr14_-_39572414 0.844 NM_006364
SEC23A
Sec23 homolog A (S. cerevisiae)
chr11_-_27723061 0.840 NM_170733
BDNF
brain-derived neurotrophic factor
chrX_+_102840412 0.839 NM_001006935
NM_001006937
NM_024863
TCEAL4


transcription elongation factor A (SII)-like 4


chr7_-_37956377 0.834 SFRP4
secreted frizzled-related protein 4
chr2_+_28615668 0.823 FOSL2
FOS-like antigen 2
chr8_-_18541441 0.818 PSD3
pleckstrin and Sec7 domain containing 3
chr5_-_131563481 0.816 NM_001017974
NM_001142598
NM_001142599
P4HA2


prolyl 4-hydroxylase, alpha polypeptide II


chr1_-_20812727 0.816 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr2_-_145277568 0.814 ZEB2
zinc finger E-box binding homeobox 2
chr7_-_6523689 0.805 NM_001100603
NM_006854
KDELR2

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2

chr7_+_128379395 0.805 CALU
calumenin
chr9_-_35689902 0.803 NM_003289
NM_213674
TPM2

tropomyosin 2 (beta)

chr13_-_49107250 0.801 NM_001268
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr1_+_99729847 0.796 NM_001166252
NM_014839
LPPR4

lipid phosphate phosphatase-related protein type 4

chr6_-_90062349 0.793 UBE2J1
ubiquitin-conjugating enzyme E2, J1, U
chr1_+_150122246 0.788 PLEKHO1
pleckstrin homology domain containing, family O member 1
chr13_-_36920491 0.787 SPG20
spastic paraplegia 20 (Troyer syndrome)
chr21_+_47545896 0.785 COL6A2
collagen, type VI, alpha 2
chr14_-_39572278 0.783 SEC23A
Sec23 homolog A (S. cerevisiae)
chr3_+_8543539 0.783 LMCD1
LIM and cysteine-rich domains 1
chr3_+_49027770 0.778 P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr7_+_128379428 0.771 CALU
calumenin
chrX_+_55744049 0.770 NM_006064
NM_016656
RRAGB

Ras-related GTP binding B

chr6_-_90062450 0.768 UBE2J1
ubiquitin-conjugating enzyme E2, J1, U
chr3_-_57583080 0.760 ARF4
ADP-ribosylation factor 4
chr14_+_62162042 0.758 NM_001530
NM_181054
HIF1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

chr6_-_7910278 0.758 NM_001145549
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr7_+_128379400 0.758 CALU
calumenin
chr2_-_86850959 0.751 NM_001198951
NM_001198952
NM_005667
RNF103


ring finger protein 103


chr2_-_86850935 0.739 RNF103
ring finger protein 103
chr16_+_31484497 0.739 NM_015927
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr19_+_50030874 0.738 NM_020650
RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr14_-_23822025 0.736 NM_016609
SLC22A17
solute carrier family 22, member 17
chr14_-_35591439 0.735 NM_017917
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr19_-_48018317 0.733 NM_003827
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr3_+_158519925 0.732 MFSD1
major facilitator superfamily domain containing 1
chr3_+_129159138 0.729 IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr3_+_129159089 0.729 IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr13_-_49107357 0.728 RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr3_+_129159150 0.727 IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr2_+_191208326 0.723 INPP1
inositol polyphosphate-1-phosphatase
chrX_+_100878350 0.722 NM_177948
ARMCX3
armadillo repeat containing, X-linked 3
chr3_+_129158949 0.718 NM_018262
NM_052985
NM_052989
NM_052990
IFT122



intraflagellar transport 122 homolog (Chlamydomonas)



chr1_+_160313172 0.718 NCSTN
nicastrin
chr12_+_6898705 0.715 CD4
CD4 molecule
chr7_-_37956515 0.713 NM_003014
SFRP4
secreted frizzled-related protein 4
chr12_-_49319211 0.711 NM_001143782
NM_016594
FKBP11

FK506 binding protein 11, 19 kDa

chr3_+_129159075 0.707 IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr7_-_27224762 0.707 NM_005523
HOXA11
homeobox A11
chr16_+_31119748 0.707 BCKDK
branched chain ketoacid dehydrogenase kinase
chr12_+_6898605 0.703 NM_000616
NM_001195014
NM_001195015
NM_001195016
NM_001195017
CD4




CD4 molecule




chr16_+_31119730 0.701 BCKDK
branched chain ketoacid dehydrogenase kinase
chr7_+_128379452 0.697 CALU
calumenin
chr10_+_70847857 0.695 SRGN
serglycin
chr20_+_35089817 0.694 NM_001042486
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr11_+_69455978 0.687 CCND1
cyclin D1
chr6_-_90062610 0.684 NM_016021
UBE2J1
ubiquitin-conjugating enzyme E2, J1, U
chr12_+_6833425 0.683 NM_001164093
COPS7A
COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chr13_-_49107185 0.682 RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr10_-_101769640 0.681 NM_015221
DNMBP
dynamin binding protein
chr17_-_13505217 0.678 NM_006042
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr17_-_78450247 0.675 NM_002522
NPTX1
neuronal pentraxin I
chr3_+_148709252 0.670 GYG1
glycogenin 1
chr9_+_103235489 0.667 NM_003692
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr6_-_7910716 0.657 NM_030810
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chrX_+_153672449 0.646 NM_004699
FAM50A
family with sequence similarity 50, member A
chr10_-_111683201 0.643 XPNPEP1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chrX_-_128657453 0.642 NM_003069
NM_139035
SMARCA1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

chrX_+_153672490 0.641 FAM50A
family with sequence similarity 50, member A
chr2_+_242254722 0.641 NM_001008491
NM_006155
SEPT2

septin 2

chr1_+_99730067 0.638 LPPR4
lipid phosphate phosphatase-related protein type 4
chr10_-_128077011 0.635 ADAM12
ADAM metallopeptidase domain 12
chr15_-_42264749 0.634 NM_139265
EHD4
EH-domain containing 4
chr14_-_93651242 0.631 NM_022151
MOAP1
modulator of apoptosis 1
chrX_+_100878101 0.630 NM_016607
NM_177947
ARMCX3

armadillo repeat containing, X-linked 3

chr1_-_160313056 0.626 COPA
coatomer protein complex, subunit alpha
chr4_-_54930706 0.626 CHIC2
cysteine-rich hydrophobic domain 2
chr10_-_118032975 0.625 NM_005264
GFRA1
GDNF family receptor alpha 1
chr16_+_31483066 0.617 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr16_+_15528324 0.611 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr5_+_170289006 0.611 RANBP17
RAN binding protein 17
chr13_-_36920603 0.608 NM_001142296
NM_015087
SPG20

spastic paraplegia 20 (Troyer syndrome)

chr19_-_11305186 0.606 NM_015493
KANK2
KN motif and ankyrin repeat domains 2
chr15_-_42264687 0.602 EHD4
EH-domain containing 4
chr3_-_121468510 0.600 NM_004487
GOLGB1
golgin B1
chr11_+_8008866 0.600 NM_003754
EIF3F
eukaryotic translation initiation factor 3, subunit F
chr17_+_80186886 0.598 NM_004207
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr1_+_160313061 0.596 NM_015331
NCSTN
nicastrin
chr1_-_160312959 0.596


chrX_-_128657440 0.595 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr19_-_4670375 0.593 NM_019107
C19orf10
chromosome 19 open reading frame 10

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.