Motif ID: CDC5L.p2

Z-value: 1.246


Transcription factors associated with CDC5L.p2:

Gene SymbolEntrez IDGene Name
CDC5L 988 CDC5 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CDC5Lchr6_+_443552500.342.0e-01Click!


Activity profile for motif CDC5L.p2.

activity profile for motif CDC5L.p2


Sorted Z-values histogram for motif CDC5L.p2

Sorted Z-values for motif CDC5L.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDC5L.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_61554938 2.439 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr6_-_49604524 2.337 NM_000324
RHAG
Rh-associated glycoprotein
chr18_+_61442611 2.330 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr4_-_15940362 2.058 NM_005130
FGFBP1
fibroblast growth factor binding protein 1
chr3_+_122044010 1.871 NM_005213
CSTA
cystatin A (stefin A)
chr9_+_100263461 1.840 NM_001166116
TMOD1
tropomodulin 1
chr10_-_21186530 1.805 NM_006393
NEBL
nebulette
chr1_+_198608216 1.671 PTPRC
protein tyrosine phosphatase, receptor type, C
chr4_+_54292035 1.542 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr4_-_15939949 1.268 FGFBP1
fibroblast growth factor binding protein 1
chr6_-_32557431 1.231 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr9_-_110252045 1.172 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr6_-_111894897 1.166 NM_001164282
TRAF3IP2
TRAF3 interacting protein 2
chr1_-_182357757 1.146 GLUL
glutamate-ammonia ligase
chr17_-_7493389 1.141 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr20_-_1472168 1.104 NM_001122962
NM_001134836
SIRPB2

signal-regulatory protein beta 2

chr15_-_55562483 1.097 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr12_+_21525801 1.065 NM_000415
IAPP
islet amyloid polypeptide
chr6_-_136847078 1.035 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr10_-_27057776 1.020 ABI1
abl-interactor 1
chr1_+_153003677 0.994 NM_003125
SPRR1B
small proline-rich protein 1B
chr5_+_147443534 0.968 NM_001127698
NM_001127699
NM_006846
SPINK5


serine peptidase inhibitor, Kazal type 5


chr4_-_140060601 0.852 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr14_-_61748510 0.839 NM_001017970
TMEM30B
transmembrane protein 30B
chr7_+_77469446 0.820 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr11_+_59824054 0.807 NM_001031666
NM_001031809
NM_006138
MS4A3


membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)


chr9_+_135854097 0.805 NM_001135031
NM_004188
GFI1B

growth factor independent 1B transcription repressor

chr5_+_137673223 0.800 NM_001135647
FAM53C
family with sequence similarity 53, member C
chr3_+_142342265 0.787 NM_002670
PLS1
plastin 1
chrX_+_99839789 0.787 NM_022144
TNMD
tenomodulin
chr11_+_59824129 0.777 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr2_-_161056573 0.770 NM_000888
ITGB6
integrin, beta 6
chr12_-_46633551 0.749 SLC38A1
solute carrier family 38, member 1
chr2_-_161056762 0.740 ITGB6
integrin, beta 6
chr6_-_136847609 0.733 MAP7
microtubule-associated protein 7
chr16_+_1728290 0.728 HN1L
hematological and neurological expressed 1-like
chr10_-_94257470 0.707 NM_001165946
IDE
insulin-degrading enzyme
chr5_-_138211054 0.707 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr1_+_241695433 0.695 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr4_-_153273683 0.688 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr8_-_110693233 0.683 NM_001099745
NM_001099746
SYBU

syntabulin (syntaxin-interacting)

chr5_+_141346401 0.672 NM_001201365
NM_183399
RNF14

ring finger protein 14

chr2_+_166095911 0.669 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr3_-_151034514 0.668 NM_023915
GPR87
G protein-coupled receptor 87
chr10_-_62493282 0.640 NM_001204403
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr15_+_80364902 0.625 NM_001242915
NM_001242916
ZFAND6

zinc finger, AN1-type domain 6

chr2_+_102615456 0.622 NM_173343
IL1R2
interleukin 1 receptor, type II
chr8_-_103137134 0.618 NM_001040630
NCALD
neurocalcin delta
chr3_-_9291251 0.618 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr18_-_31628557 0.614 NM_001198549
NOL4
nucleolar protein 4
chr1_+_152956563 0.599 NM_001199828
NM_005987
SPRR1A

small proline-rich protein 1A

chr6_-_32497925 0.596 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr9_+_75766794 0.595 ANXA1
annexin A1
chr1_-_182357871 0.586 GLUL
glutamate-ammonia ligase
chr6_+_4890225 0.583 NM_001143971
CDYL
chromodomain protein, Y-like
chr12_-_52828105 0.579 NM_004693
KRT75
keratin 75
chrX_+_52780279 0.577 NM_003147
NM_175698
NM_001164417
SSX2

SSX2B
synovial sarcoma, X breakpoint 2

synovial sarcoma, X breakpoint 2B
chrX_-_106449543 0.572 NM_017681
NUP62CL
nucleoporin 62kDa C-terminal like
chrX_-_110654373 0.566 NM_000555
DCX
doublecortin
chr7_+_18535817 0.563 NM_058176
NM_178425
HDAC9

histone deacetylase 9

chr12_+_28410132 0.562 NM_018318
CCDC91
coiled-coil domain containing 91
chr1_+_100326765 0.557 NM_000645
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr9_+_75766777 0.557 NM_000700
ANXA1
annexin A1
chr1_-_51887740 0.556 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr12_+_25205488 0.544 LRMP
lymphoid-restricted membrane protein
chr16_+_1728256 0.543 NM_144570
HN1L
hematological and neurological expressed 1-like
chr11_-_114466397 0.535 FAM55D
family with sequence similarity 55, member D
chr1_+_50571963 0.529 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr18_-_51690988 0.522 MBD2
methyl-CpG binding domain protein 2
chr7_+_18535351 0.521 NM_001204145
NM_001204146
NM_014707
NM_178423
HDAC9



histone deacetylase 9



chr7_-_16505292 0.519 NM_015464
SOSTDC1
sclerostin domain containing 1
chr1_+_25598883 0.518 NM_001127691
NM_016124
RHD

Rh blood group, D antigen

chr12_-_102591547 0.513 NM_002674
PMCH
pro-melanin-concentrating hormone
chr7_-_14025826 0.511 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr5_-_138210992 0.507 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chrX_+_30261847 0.500 NM_002363
NM_177415
MAGEB1

melanoma antigen family B, 1

chr7_-_122839999 0.497 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr11_-_84634437 0.491 NM_001364
DLG2
discs, large homolog 2 (Drosophila)
chr1_-_25747276 0.491 NM_020485
NM_138616
NM_138617
NM_138618
RHCE



RHD
Rh blood group, CcEe antigens



Rh blood group, D antigen
chr5_+_140165875 0.488 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr21_-_15918635 0.486 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr12_-_54689536 0.483 NM_006163
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr1_-_93257950 0.477 NM_005665
EVI5
ecotropic viral integration site 5
chr2_+_172821874 0.467 HAT1
histone acetyltransferase 1
chrX_+_123234462 0.467 STAG2
stromal antigen 2
chr12_-_15114495 0.463 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr4_-_123377471 0.462 NM_000586
IL2
interleukin 2
chr6_+_14117486 0.459 NM_001251901
CD83
CD83 molecule
chr5_-_137848517 0.453 ETF1
eukaryotic translation termination factor 1
chr7_+_28452143 0.449 NM_182898
CREB5
cAMP responsive element binding protein 5
chr1_-_150738232 0.448 CTSS
cathepsin S
chr8_+_27179918 0.431 NM_004103
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr2_-_100722328 0.428 AFF3
AF4/FMR2 family, member 3
chr11_-_83984230 0.428 NM_001142700
DLG2
discs, large homolog 2 (Drosophila)
chr10_+_91152321 0.428 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr1_+_100316530 0.424 NM_000646
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chrX_+_65384078 0.423 NM_001130860
NM_014799
HEPH

hephaestin

chr21_+_39628663 0.422 NM_002243
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr5_+_132428394 0.420 HSPA4
heat shock 70kDa protein 4
chr4_-_76957139 0.420 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chr3_-_138478184 0.419 NM_006219
PIK3CB
phosphoinositide-3-kinase, catalytic, beta polypeptide
chr19_-_14889347 0.415 NM_013447
NM_152916
NM_152917
NM_152918
NM_152919
NM_152920
NM_152921
EMR2






egf-like module containing, mucin-like, hormone receptor-like 2






chr3_+_151985828 0.404 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chrX_-_118726852 0.403 NM_001173488
NKRF
NFKB repressing factor
chr3_-_57234279 0.403 NM_003865
HESX1
HESX homeobox 1
chr11_-_13517525 0.401 NM_000315
PTH
parathyroid hormone
chr8_+_32504250 0.400 NM_013959
NRG1
neuregulin 1
chr12_-_91398757 0.399 NM_004950
EPYC
epiphycan
chr11_-_84028379 0.397 NM_001206769
DLG2
discs, large homolog 2 (Drosophila)
chr7_+_129269916 0.396 NM_001040110
NRF1
nuclear respiratory factor 1
chrX_-_48056198 0.393 NM_021015
NM_175723
SSX5

synovial sarcoma, X breakpoint 5

chr4_-_144940439 0.392 NM_002100
GYPB
glycophorin B (MNS blood group)
chr12_-_53601051 0.388 ITGB7
integrin, beta 7
chr16_+_1728283 0.388 HN1L
hematological and neurological expressed 1-like
chr6_-_155777036 0.383 NM_015718
NOX3
NADPH oxidase 3
chr3_-_141747434 0.376 NM_001178141
NM_001178142
NM_006286
TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr6_-_133084585 0.375 NM_078488
VNN2
vanin 2
chr6_-_90024936 0.375 NM_002043
GABRR2
gamma-aminobutyric acid (GABA) receptor, rho 2
chr13_-_41556360 0.375 NM_001145353
ELF1
E74-like factor 1 (ets domain transcription factor)
chrX_+_65382432 0.373 NM_138737
HEPH
hephaestin
chr1_-_226926875 0.370 NM_002221
ITPKB
inositol-trisphosphate 3-kinase B
chr3_-_196911001 0.369 NM_001204387
NM_001204388
DLG1

discs, large homolog 1 (Drosophila)

chr1_+_43291230 0.368 NM_018538
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr1_-_150738292 0.365 NM_001199739
NM_004079
CTSS

cathepsin S

chr6_-_32784727 0.360 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr3_+_63884074 0.358 NM_001177387
ATXN7
ataxin 7
chr12_+_25205180 0.358 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chr10_-_98031154 0.354 NM_001114094
NM_013314
BLNK

B-cell linker

chr8_-_86253863 0.353 NM_001164830
CA1
carbonic anhydrase I
chr16_-_46782104 0.352 NM_182493
MYLK3
myosin light chain kinase 3
chr3_-_169587598 0.348 NM_024727
LRRC31
leucine rich repeat containing 31
chr4_-_176733901 0.348 GPM6A
glycoprotein M6A
chr8_+_75736771 0.347 NM_015886
PI15
peptidase inhibitor 15
chr4_-_72649734 0.344 NM_000583
GC
group-specific component (vitamin D binding protein)
chr7_+_80267922 0.344 CD36
CD36 molecule (thrombospondin receptor)
chr7_+_64126481 0.341 NM_001013746
NM_016220
ZNF107

zinc finger protein 107

chrX_-_23925947 0.338 NM_024122
APOO
apolipoprotein O
chr10_-_121296044 0.338 NM_002925
RGS10
regulator of G-protein signaling 10
chr11_-_84634219 0.335 DLG2
discs, large homolog 2 (Drosophila)
chr10_-_62493077 0.335 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_+_86934525 0.333 NM_001285
CLCA1
chloride channel accessory 1
chr2_+_169757749 0.328 NM_001081686
NM_021176
G6PC2

glucose-6-phosphatase, catalytic, 2

chr9_-_95298251 0.325 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr6_+_12717036 0.324 NM_001242648
NM_030948
PHACTR1

phosphatase and actin regulator 1

chrX_+_78003205 0.320 NM_005296
LPAR4
lysophosphatidic acid receptor 4
chr12_-_53600999 0.319 NM_000889
ITGB7
integrin, beta 7
chr12_-_102512277 0.314 NM_024057
NUP37
nucleoporin 37kDa
chr11_+_134201897 0.313 GLB1L2
galactosidase, beta 1-like 2
chr5_+_102465256 0.312 NM_015216
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr12_-_54653317 0.311 NM_001127322
CBX5
chromobox homolog 5
chr12_-_54653369 0.310 NM_001127321
CBX5
chromobox homolog 5
chr10_-_62332666 0.309 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr14_-_107131217 0.309 IGHA1
immunoglobulin heavy constant alpha 1
chr3_+_4535030 0.308 NM_001099952
NM_001168272
NM_002222
ITPR1


inositol 1,4,5-trisphosphate receptor, type 1


chr2_-_2334887 0.308 NM_015025
MYT1L
myelin transcription factor 1-like
chr10_+_35484054 0.307 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr5_+_161277702 0.307 NM_001127648
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr4_+_106631966 0.306 NM_001031720
GSTCD
glutathione S-transferase, C-terminal domain containing
chr18_-_24445652 0.306 NM_001650
AQP4
aquaporin 4
chr1_+_167298280 0.301 NM_001198783
POU2F1
POU class 2 homeobox 1
chr8_+_19796581 0.301 NM_000237
LPL
lipoprotein lipase
chr1_+_174769034 0.301 NM_001243765
RABGAP1L
RAB GTPase activating protein 1-like
chr3_+_178276487 0.300 NM_005832
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr3_+_171561138 0.298 NM_001164436
TMEM212
transmembrane protein 212
chrX_+_110366304 0.296 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr7_-_100076754 0.293 NM_030935
TSC22D4
TSC22 domain family, member 4
chr4_-_71532206 0.292 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr5_+_115898218 0.288


chr11_-_118134956 0.284 MPZL2
myelin protein zero-like 2
chr14_-_23877480 0.284 NM_002471
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr3_-_33700480 0.283 CLASP2
cytoplasmic linker associated protein 2
chr21_-_36421586 0.282 NM_001754
RUNX1
runt-related transcription factor 1
chr3_-_119278402 0.281 NM_005191
CD80
CD80 molecule
chr7_+_139528951 0.280 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr3_+_121774208 0.275 NM_001206924
NM_001206925
NM_175862
CD86


CD86 molecule


chr1_-_32169619 0.275 NM_001856
COL16A1
collagen, type XVI, alpha 1
chr4_-_83347222 0.274 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr13_-_46742678 0.273 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_236557643 0.272 NM_145861
EDARADD
EDAR-associated death domain
chr1_-_160681552 0.269 NM_001778
CD48
CD48 molecule
chr13_-_41556188 0.269 ELF1
E74-like factor 1 (ets domain transcription factor)
chr13_-_99910548 0.269 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr1_-_150738255 0.268 CTSS
cathepsin S
chr9_+_125132823 0.268 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_-_158300517 0.268 NM_004288
CYTIP
cytohesin 1 interacting protein
chr2_-_163008913 0.262 NM_002054
GCG
glucagon
chr1_+_59775749 0.261 NM_001244714
FGGY
FGGY carbohydrate kinase domain containing
chr14_-_107113943 0.260 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr2_-_215896809 0.258 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chrX_+_119737743 0.257 NM_014060
MCTS1
malignant T cell amplified sequence 1
chr14_-_37641864 0.257 NM_001171170
NM_030631
SLC25A21

solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21

chr20_-_1974393 0.256 NM_001190900
PDYN
prodynorphin
chrX_-_24690740 0.256 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr10_+_35426709 0.252 NM_183011
NM_183012
CREM

cAMP responsive element modulator

chr2_-_15701445 0.251 NM_015909
NBAS
neuroblastoma amplified sequence
chr3_+_150321065 0.249 NM_016275
SELT
selenoprotein T
chr20_+_42984338 0.247 NM_001030003
NM_001030004
NM_175914
HNF4A


hepatocyte nuclear factor 4, alpha


chr6_+_26156558 0.244 NM_005321
HIST1H1E
histone cluster 1, H1e
chr4_-_71532341 0.243 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr14_-_106405633 0.241 IGHM
immunoglobulin heavy constant mu

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
16.84 1.61e-02 GO:0004866 endopeptidase inhibitor activity
16.55 1.70e-02 GO:0030414 peptidase inhibitor activity
16.13 1.83e-02 GO:0061135 endopeptidase regulator activity
13.32 3.19e-02 GO:0061134 peptidase regulator activity