Motif ID: CEBPA,B_DDIT3.p2

Z-value: 0.928


Transcription factors associated with CEBPA,B_DDIT3.p2:

Gene SymbolEntrez IDGene Name
CEBPA 1050 CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB 1051 CCAAT/enhancer binding protein (C/EBP), beta
DDIT3 1649 DNA-damage-inducible transcript 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CEBPAchr19_-_337934290.741.1e-03Click!
CEBPBchr20_+_488071190.552.6e-02Click!
DDIT3chr12_-_57914287-0.039.1e-01Click!


Activity profile for motif CEBPA,B_DDIT3.p2.

activity profile for motif CEBPA,B_DDIT3.p2


Sorted Z-values histogram for motif CEBPA,B_DDIT3.p2

Sorted Z-values for motif CEBPA,B_DDIT3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CEBPA,B_DDIT3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_186330844 5.241 NM_001622
 AHSG
alpha-2-HS-glycoprotein
chr3_+_186330859 5.223 AHSG
alpha-2-HS-glycoprotein
chr3_+_186330711 4.508 AHSG
alpha-2-HS-glycoprotein
chr17_-_39092714 3.578 KRT23
keratin 23 (histone deacetylase inducible)
chr17_-_64225496 3.364 NM_000042
 APOH
apolipoprotein H (beta-2-glycoprotein I)
chr6_+_31895201 2.520 NM_000063
NM_001145903
 C2

complement component 2

chr19_+_45452427 2.500 APOC2
apolipoprotein C-II
chr10_-_116444112 2.473 ABLIM1
actin binding LIM protein 1
chr6_+_31895401 2.377 C2
complement component 2
chr10_-_116444374 2.322 NM_001003407
NM_001003408
 ABLIM1

actin binding LIM protein 1

chr9_+_117092068 2.152 NM_000608
 ORM2
orosomucoid 2
chr9_+_117085302 2.002 NM_000607
 ORM1
orosomucoid 1
chr4_-_10023094 1.966 NM_020041
 SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr12_-_122296619 1.862 NM_002150
 HPD
4-hydroxyphenylpyruvate dioxygenase
chr9_-_123812535 1.859 NM_001735
 C5
complement component 5
chr2_-_216300770 1.810 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
 FN1





fibronectin 1





chr8_-_17743062 1.679 FGL1
fibrinogen-like 1
chrX_-_105282714 1.617 NM_000354
 SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr3_-_79817058 1.432 NM_002941
 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr1_+_150954498 1.331 NM_003568
 ANXA9
annexin A9

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
Enrichment   P-value GO Accession GO Term
183.35 1.07e-02 GO:0051006 positive regulation of lipoprotein lipase activity
62.89 8.73e-05 GO:0006953 acute-phase response
42.34 4.42e-04 GO:0002526 acute inflammatory response
30.59 2.67e-02 GO:0050680 negative regulation of epithelial cell proliferation
27.54 3.66e-02 GO:0072376 protein activation cascade
25.42 4.64e-02 GO:0032102 negative regulation of response to external stimulus
15.76 2.97e-04 GO:0032101 regulation of response to external stimulus
11.27 1.33e-02 GO:0006954 inflammatory response

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
Enrichment   P-value GO Accession GO Term
157.16 3.19e-03 GO:0005577 fibrinogen complex
100.03 8.31e-03 GO:0042627 chylomicron
61.14 2.29e-02 GO:0034361 very-low-density lipoprotein particle
61.14 2.29e-02 GO:0034385 triglyceride-rich lipoprotein particle
50.04 3.45e-02 GO:0034364 high-density lipoprotein particle
10.79 3.84e-10 GO:0005615 extracellular space
8.58 6.94e-09 GO:0044421 extracellular region part
5.06 4.80e-06 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
549.96 1.23e-04 GO:0060230 lipoprotein lipase activator activity
220.01 1.23e-03 GO:0060229 lipase activator activity
19.51 1.69e-03 GO:0004866 endopeptidase inhibitor activity
19.17 1.81e-03 GO:0030414 peptidase inhibitor activity
18.68 2.00e-03 GO:0061135 endopeptidase regulator activity
15.43 4.23e-03 GO:0061134 peptidase regulator activity
12.43 1.43e-03 GO:0004857 enzyme inhibitor activity