Motif ID: CREB1.p2

Z-value: 1.030


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CREB1chr2_+_2083946920.185.1e-01Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_15850776 1.943 NM_001229
NM_032996
CASP9

caspase 9, apoptosis-related cysteine peptidase

chr14_+_68086633 1.725 ARG2
arginase, type II
chr13_-_36871968 1.600 NM_001198910
NM_001144981
NM_001144982
NM_001144983
NM_001144984
NM_001144985
NM_001144986
NM_001198908
CCDC169-SOHLH2
CCDC169






CCDC169-SOHLH2 readthrough
coiled-coil domain containing 169






chr18_+_2571509 1.398 NM_006101
NDC80
NDC80 kinetochore complex component homolog (S. cerevisiae)
chr18_+_2571587 1.364 NDC80
NDC80 kinetochore complex component homolog (S. cerevisiae)
chr11_+_68452007 1.302 GAL
galanin prepropeptide
chr11_+_68451978 1.287 NM_015973
GAL
galanin prepropeptide
chr1_+_26496382 1.252 NM_015871
ZNF593
zinc finger protein 593
chr1_-_200638996 1.249 DDX59
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chr1_+_12040475 1.238 MFN2
mitofusin 2
chr14_+_68086570 1.231 NM_001172
ARG2
arginase, type II
chr1_-_15850718 1.228 CASP9
caspase 9, apoptosis-related cysteine peptidase
chr3_+_185303961 1.175 NM_021627
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr10_-_99094427 1.156 NM_012083
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr12_+_132629014 1.115 NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr16_+_19078958 1.106 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr14_+_68086655 1.084 ARG2
arginase, type II
chr17_-_76836852 1.071 NM_025090
USP36
ubiquitin specific peptidase 36
chr11_-_28129646 1.054 KIF18A
kinesin family member 18A
chr7_-_140624280 0.923 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr1_+_45205558 0.902 KIF2C
kinesin family member 2C
chr16_-_3767449 0.902 NM_016292
TRAP1
TNF receptor-associated protein 1
chr1_+_40627031 0.898 NM_012421
RLF
rearranged L-myc fusion
chr14_-_103988829 0.879 CKB
creatine kinase, brain
chr1_-_15850692 0.878 CASP9
caspase 9, apoptosis-related cysteine peptidase
chr16_+_19078916 0.877 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr6_-_30523933 0.871 GNL1
guanine nucleotide binding protein-like 1
chr4_-_122744782 0.867 CCNA2
cyclin A2
chr1_+_52082755 0.835 OSBPL9
oxysterol binding protein-like 9
chr1_+_150980895 0.831 NM_021222
PRUNE
prune homolog (Drosophila)
chr1_-_119683210 0.823 NM_015836
NM_201263
WARS2

tryptophanyl tRNA synthetase 2, mitochondrial

chr1_+_45205533 0.823 KIF2C
kinesin family member 2C
chr11_+_66610882 0.803 NM_001032279
NM_005133
RCE1

RCE1 homolog, prenyl protein protease (S. cerevisiae)

chr6_-_31846751 0.792 SLC44A4
solute carrier family 44, member 4
chr1_+_45205466 0.788 NM_006845
KIF2C
kinesin family member 2C
chr6_+_30524485 0.786 NM_001077497
NM_025263
PRR3

proline rich 3

chr9_-_140353785 0.777 NM_001130969
NM_001130970
NM_001130971
NM_001178064
NM_015537
NELF




nasal embryonic LHRH factor




chr5_+_43121592 0.768 ZNF131
zinc finger protein 131
chr14_-_55369163 0.768 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr1_+_40627055 0.768 RLF
rearranged L-myc fusion
chr6_-_31846816 0.754 NM_001178044
NM_025257
SLC44A4

solute carrier family 44, member 4

chr11_-_119252364 0.752 NM_001243759
NM_004205
USP2

ubiquitin specific peptidase 2

chr18_-_2571422 0.749 NM_022840
METTL4
methyltransferase like 4
chr11_-_62607043 0.721 WDR74
WD repeat domain 74
chr3_-_33759684 0.721 NM_015097
CLASP2
cytoplasmic linker associated protein 2
chr12_-_10766130 0.718 NM_018048
MAGOHB
mago-nashi homolog B (Drosophila)
chr11_-_119252267 0.702 USP2
ubiquitin specific peptidase 2
chr4_-_122744978 0.701 NM_001237
CCNA2
cyclin A2
chr8_-_17104266 0.695 NM_013354
NM_054026
CNOT7

CCR4-NOT transcription complex, subunit 7

chr16_+_19079220 0.688 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr6_-_49604524 0.684 NM_000324
RHAG
Rh-associated glycoprotein
chr6_-_26285726 0.679 NM_003543
HIST1H4H
histone cluster 1, H4h
chr17_+_685606 0.662 RNMTL1
RNA methyltransferase like 1
chr1_-_161147209 0.660 B4GALT3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr16_-_20911560 0.658 NM_173475
DCUN1D3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr1_+_12040504 0.658 MFN2
mitofusin 2
chr5_+_43121641 0.657 NM_003432
ZNF131
zinc finger protein 131
chr11_-_3818971 0.653 NM_005387
NM_016320
NM_139131
NM_139132
NUP98



nucleoporin 98kDa



chr9_-_140353748 0.651 NELF
nasal embryonic LHRH factor
chr6_-_30523502 0.651 GNL1
guanine nucleotide binding protein-like 1
chr9_+_134000939 0.642 NM_005085
NUP214
nucleoporin 214kDa
chr1_-_52870058 0.638 NM_001190818
NM_001190819
NM_004153
ORC1


origin recognition complex, subunit 1


chr20_+_42295747 0.638 MYBL2
v-myb myeloblastosis viral oncogene homolog (avian)-like 2
chr16_+_81040515 0.634 CENPN
centromere protein N
chr17_+_8152594 0.630 NM_012393
PFAS
phosphoribosylformylglycinamidine synthase
chr10_+_85899184 0.629 NM_014394
GHITM
growth hormone inducible transmembrane protein
chr6_+_44214786 0.621 NM_007355
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr9_-_139981102 0.615 LOC100289341
uncharacterized LOC100289341
chr10_+_22634373 0.610 NM_001253854
NM_001253855
NM_012443
NM_172242
SPAG6



sperm associated antigen 6



chr6_+_44214853 0.609 HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr7_+_116660263 0.603 ST7
suppression of tumorigenicity 7
chr17_-_685385 0.601 NM_016080
GLOD4
glyoxalase domain containing 4
chr11_-_28129701 0.601 NM_031217
KIF18A
kinesin family member 18A
chr17_+_685512 0.600 NM_018146
RNMTL1
RNA methyltransferase like 1
chr19_-_18392413 0.598 NM_005354
JUND
jun D proto-oncogene
chr11_-_28129687 0.592 KIF18A
kinesin family member 18A
chr10_+_21823093 0.589 NM_001195627
NM_001195628
NM_001195630
NM_004641
MLLT10



myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10



chr1_-_245025958 0.586 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr1_+_12040237 0.585 NM_001127660
NM_014874
MFN2

mitofusin 2

chr17_+_7155371 0.574 NM_203415
NM_015362
NM_203413
NM_203414
C17orf81



chromosome 17 open reading frame 81



chr18_-_267987 0.570 NM_005131
THOC1
THO complex 1
chr6_+_20404033 0.570 NM_001243076
E2F3
E2F transcription factor 3
chr10_+_21823266 0.568 MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr17_-_42201009 0.564 NM_001015053
NM_005474
HDAC5

histone deacetylase 5

chr20_-_22564893 0.557 FOXA2
forkhead box A2
chrX_+_102470003 0.541 NM_001080425
NM_001127688
BEX4

brain expressed, X-linked 4

chr17_-_42200957 0.540 HDAC5
histone deacetylase 5
chr15_+_66797632 0.537 ZWILCH
Zwilch, kinetochore associated, homolog (Drosophila)
chr19_+_39421562 0.536 NM_021107
NM_033363
MRPS12

mitochondrial ribosomal protein S12

chr5_+_44808967 0.534 NM_016640
MRPS30
mitochondrial ribosomal protein S30
chr1_-_229643996 0.532 NUP133
nucleoporin 133kDa
chr8_-_17104103 0.530 CNOT7
CCR4-NOT transcription complex, subunit 7
chr14_-_103995336 0.520


chr11_+_34127208 0.519 NAT10
N-acetyltransferase 10 (GCN5-related)
chr17_+_53342356 0.510 HLF
hepatic leukemia factor
chr7_+_107204402 0.507 NM_181581
DUS4L
dihydrouridine synthase 4-like (S. cerevisiae)
chr16_-_67694602 0.506 NM_001082486
NM_001082487
NM_022914
ACD


adrenocortical dysplasia homolog (mouse)


chr15_+_40861527 0.504 RPUSD2
RNA pseudouridylate synthase domain containing 2
chr1_+_70876863 0.504 NM_001190463
NM_001902
NM_153742
CTH


cystathionase (cystathionine gamma-lyase)


chr10_+_21823382 0.496 MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr1_+_222791151 0.494 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr15_+_40861531 0.487 NM_152260
RPUSD2
RNA pseudouridylate synthase domain containing 2
chr15_+_40861509 0.487 RPUSD2
RNA pseudouridylate synthase domain containing 2
chr11_-_78285718 0.486 NARS2
asparaginyl-tRNA synthetase 2, mitochondrial (putative)
chr1_-_228645517 0.483 NM_033445
HIST3H2A
histone cluster 3, H2a
chr11_+_34127110 0.482 NM_001144030
NM_024662
NAT10

N-acetyltransferase 10 (GCN5-related)

chr2_+_97001506 0.481 NCAPH
non-SMC condensin I complex, subunit H
chr7_+_100027253 0.478 NM_019606
MEPCE
methylphosphate capping enzyme
chr22_-_20104428 0.478 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr11_-_78285869 0.475 NM_001243251
NM_024678
NARS2

asparaginyl-tRNA synthetase 2, mitochondrial (putative)

chr16_-_30007315 0.475 NM_001197323
NM_003609
HIRIP3

HIRA interacting protein 3

chr4_+_144434555 0.471 NM_003601
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr10_-_23003443 0.470 NM_005028
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr1_-_894651 0.469 NM_015658
NOC2L
nucleolar complex associated 2 homolog (S. cerevisiae)
chr11_-_9025531 0.464 NM_020645
NRIP3
nuclear receptor interacting protein 3
chr7_+_116660291 0.457 ST7
suppression of tumorigenicity 7
chr1_-_229644077 0.455 NM_018230
NUP133
nucleoporin 133kDa
chr2_-_97535669 0.455 NM_017789
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr20_+_42295708 0.452 NM_002466
MYBL2
v-myb myeloblastosis viral oncogene homolog (avian)-like 2
chr3_-_33759540 0.451 CLASP2
cytoplasmic linker associated protein 2
chr1_-_193028389 0.450 UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr15_+_40861491 0.449 RPUSD2
RNA pseudouridylate synthase domain containing 2
chr8_+_86089618 0.447 NM_001083588
NM_001951
E2F5

E2F transcription factor 5, p130-binding

chr3_-_10067989 0.447 CIDECP
cell death-inducing DFFA-like effector c pseudogene
chr14_+_93651295 0.445 NM_015676
NM_001098621
C14orf109

chromosome 14 open reading frame 109

chr19_+_36103616 0.443 NM_015302
HAUS5
HAUS augmin-like complex, subunit 5
chr2_+_75061234 0.443 HK2
hexokinase 2
chr3_+_158288952 0.443 NM_001130156
NM_001130157
NM_001195432
NM_001195433
NM_001195434
NM_022443
MLF1





myeloid leukemia factor 1





chr17_+_7155821 0.442 C17orf81
chromosome 17 open reading frame 81
chr7_+_56019552 0.432 NM_015969
MRPS17
mitochondrial ribosomal protein S17
chr17_-_13505217 0.431 NM_006042
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr17_-_76836608 0.430 USP36
ubiquitin specific peptidase 36
chr5_-_32174397 0.430 NM_022130
GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr1_+_10270680 0.430 NM_015074
NM_183416
KIF1B

kinesin family member 1B

chr19_-_5720155 0.429 LONP1
lon peptidase 1, mitochondrial
chr19_-_55668956 0.427 NM_000363
TNNI3
troponin I type 3 (cardiac)
chr2_-_157189040 0.424 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr6_-_27114577 0.420 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr19_-_5720136 0.420 LONP1
lon peptidase 1, mitochondrial
chr5_+_68389775 0.419 NM_001251969
NM_022902
NM_024055
SLC30A5


solute carrier family 30 (zinc transporter), member 5


chr8_+_23386386 0.419 SLC25A37
solute carrier family 25, member 37
chr1_+_40627066 0.416 RLF
rearranged L-myc fusion
chr6_-_43027114 0.416 NM_015950
MRPL2
mitochondrial ribosomal protein L2
chr3_+_170075521 0.416 SKIL
SKI-like oncogene
chr16_+_2039945 0.416 NM_004209
SYNGR3
synaptogyrin 3
chr12_+_132628978 0.414 NM_024078
NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr20_+_37377096 0.412 NM_024855
ACTR5
ARP5 actin-related protein 5 homolog (yeast)
chr19_-_9695166 0.408 NM_001008727
ZNF121
zinc finger protein 121
chr20_+_62612576 0.407


chr12_-_94853453 0.407 CCDC41
coiled-coil domain containing 41
chr4_+_170541728 0.406 CLCN3
chloride channel 3
chr7_+_87505737 0.405 DBF4
DBF4 homolog (S. cerevisiae)
chr17_-_71308118 0.404 NM_012121
CDC42EP4
CDC42 effector protein (Rho GTPase binding) 4
chr15_+_41952572 0.403 NM_001080541
NM_001164273
MGA

MAX gene associated

chr3_+_52719935 0.401 NM_014366
NM_206825
NM_206826
GNL3


guanine nucleotide binding protein-like 3 (nucleolar)


chr21_-_44527603 0.399 U2AF1
U2 small nuclear RNA auxiliary factor 1
chr15_-_91537724 0.399 NM_003981
NM_199413
NM_199414
PRC1


protein regulator of cytokinesis 1


chr1_-_235292206 0.397 NM_014765
TOMM20
translocase of outer mitochondrial membrane 20 homolog (yeast)
chr2_+_85829962 0.397 USP39
ubiquitin specific peptidase 39
chr5_+_137801166 0.394 EGR1
early growth response 1
chr17_-_72869068 0.393 NM_004110
NM_024417
FDXR

ferredoxin reductase

chr8_+_98788014 0.392 LAPTM4B
lysosomal protein transmembrane 4 beta
chr17_-_5026396 0.391 NM_014519
ZNF232
zinc finger protein 232
chr19_-_18392436 0.390 JUND
jun D proto-oncogene
chr4_-_79860369 0.387 NM_001040202
PAQR3
progestin and adipoQ receptor family member III
chr4_+_100485239 0.386 NM_000253
MTTP
microsomal triglyceride transfer protein
chr2_-_128568666 0.384 WDR33
WD repeat domain 33
chr8_+_98787808 0.383 NM_018407
LAPTM4B
lysosomal protein transmembrane 4 beta
chr7_+_100026412 0.382 NM_001194990
NM_001194991
NM_001194992
MEPCE


methylphosphate capping enzyme


chr8_-_145743151 0.382 NM_004260
RECQL4
RecQ protein-like 4
chr16_-_4897265 0.382 NM_032569
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr3_+_127317271 0.380 MCM2
minichromosome maintenance complex component 2
chr20_+_62612493 0.379 PRPF6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)
chr16_+_68298326 0.378 NM_001076785
NM_003983
SLC7A6

solute carrier family 7 (amino acid transporter light chain, y+L system), member 6

chr19_-_40336944 0.378 FBL
fibrillarin
chr1_-_51425464 0.377 FAF1
Fas (TNFRSF6) associated factor 1
chr17_+_58677489 0.377 NM_003620
PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr15_+_72766689 0.376 ARIH1
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
chr7_+_100026413 0.374 MEPCE
methylphosphate capping enzyme
chr6_+_49431090 0.371 NM_018132
CENPQ
centromere protein Q
chr12_-_82752154 0.370 NM_014167
CCDC59
coiled-coil domain containing 59
chr7_+_107531585 0.370 NM_000108
DLD
dihydrolipoamide dehydrogenase
chr3_+_127317274 0.368 MCM2
minichromosome maintenance complex component 2
chr4_+_170541690 0.367 CLCN3
chloride channel 3
chr11_-_3818706 0.366 NUP98
nucleoporin 98kDa
chr19_+_59055826 0.365 NM_005762
TRIM28
tripartite motif containing 28
chr7_-_8301767 0.363 NM_001136020
ICA1
islet cell autoantigen 1, 69kDa
chr21_-_44527681 0.363 NM_001025203
NM_001025204
NM_006758
U2AF1


U2 small nuclear RNA auxiliary factor 1


chr6_-_34664587 0.363 NM_022758
NM_024294
C6orf106

chromosome 6 open reading frame 106

chrX_+_30671456 0.362 NM_000167
NM_001128127
NM_001205019
NM_203391
GK



glycerol kinase



chr1_-_193028490 0.361 NM_001199261
NM_001199262
NM_001199263
NM_015984
UCHL5



ubiquitin carboxyl-terminal hydrolase L5



chr5_-_37371198 0.361 NUP155
nucleoporin 155kDa
chr5_-_133561745 0.360 PPP2CA
protein phosphatase 2, catalytic subunit, alpha isozyme
chr3_+_43328001 0.358 NM_001100594
NM_017719
SNRK

SNF related kinase

chr11_+_70116771 0.358 NM_003626
NM_177423
PPFIA1

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1

chr12_+_112279781 0.356 MAPKAPK5
mitogen-activated protein kinase-activated protein kinase 5
chr3_+_73045939 0.354 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr12_+_112280044 0.354 MAPKAPK5
mitogen-activated protein kinase-activated protein kinase 5
chr20_+_62612464 0.353 PRPF6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)
chr1_+_202976478 0.351 TMEM183B
transmembrane protein 183B

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
28.98 2.85e-03 GO:0008234 cysteine-type peptidase activity
3.90 1.27e-02 GO:0016787 hydrolase activity