Motif ID: CUX2.p2

Z-value: 0.950


Transcription factors associated with CUX2.p2:

Gene SymbolEntrez IDGene Name
CUX2 23316 cut-like homeobox 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CUX2chr12_+_1114718270.431.0e-01Click!


Activity profile for motif CUX2.p2.

activity profile for motif CUX2.p2


Sorted Z-values histogram for motif CUX2.p2

Sorted Z-values for motif CUX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CUX2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 120 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_89165652 5.062


chr13_-_46756295 4.705 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_198608136 3.819 NM_002838
NM_080921
NM_080923
 PTPRC


protein tyrosine phosphatase, receptor type, C


chr13_-_46756291 3.457 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_198608216 3.305 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_+_198608244 2.745 PTPRC
protein tyrosine phosphatase, receptor type, C
chr16_+_12058963 1.639 NM_001192
 TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr13_-_46756326 1.572 NM_002298
 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_51887740 1.201 NM_001159969
 EPS15
epidermal growth factor receptor pathway substrate 15
chr6_+_32709162 1.190 NM_020056
 HLA-DQA1
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 1
major histocompatibility complex, class II, DQ alpha 2
chr12_-_54653317 1.082 NM_001127322
 CBX5
chromobox homolog 5
chr12_+_6554032 1.014 NM_001242
 CD27
CD27 molecule
chr9_-_5304579 0.981 NM_005059
NM_134441
 RLN2

relaxin 2

chr2_+_202004997 0.951 NM_001202515
 CFLAR
CASP8 and FADD-like apoptosis regulator
chr12_-_54653369 0.906 NM_001127321
 CBX5
chromobox homolog 5
chr17_-_46687925 0.835 HOXB7
homeobox B7
chr6_-_154677868 0.810 NM_001130700
NM_015553
 IPCEF1

interaction protein for cytohesin exchange factors 1

chr1_+_111413820 0.770 NM_001040033
 CD53
CD53 molecule
chr10_+_92631241 0.763 RPP30
ribonuclease P/MRP 30kDa subunit
chr13_+_53035227 0.751 CKAP2
cytoskeleton associated protein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 29 entries
Enrichment   P-value GO Accession GO Term
175.78 4.37e-03 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
74.08 2.54e-02 GO:0050871 positive regulation of B cell activation
57.86 1.07e-03 GO:0050852 T cell receptor signaling pathway
54.16 4.78e-02 GO:0019882 antigen processing and presentation
46.96 2.00e-03 GO:0050851 antigen receptor-mediated signaling pathway
43.13 2.59e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
41.85 2.83e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
36.61 1.51e-04 GO:0051251 positive regulation of lymphocyte activation
34.18 1.99e-04 GO:0002696 positive regulation of leukocyte activation
33.57 2.14e-04 GO:0050867 positive regulation of cell activation
33.05 5.76e-03 GO:0050870 positive regulation of T cell activation
32.79 5.89e-03 GO:0002252 immune effector process
29.24 3.72e-04 GO:0051249 regulation of lymphocyte activation
26.96 1.06e-02 GO:0050863 regulation of T cell activation
26.63 5.41e-04 GO:0002694 regulation of leukocyte activation
25.82 1.20e-02 GO:0002757 immune response-activating signal transduction
25.55 6.38e-04 GO:0050865 regulation of cell activation
25.36 1.27e-02 GO:0002764 immune response-regulating signaling pathway
24.07 1.48e-02 GO:0019221 cytokine-mediated signaling pathway
21.73 2.01e-02 GO:0071345 cellular response to cytokine stimulus

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
200.87 1.48e-03 GO:0042613 MHC class II protein complex
93.80 7.05e-03 GO:0042611 MHC protein complex
20.58 1.06e-02 GO:0010008 endosome membrane
20.38 1.09e-02 GO:0044440 endosomal part
5.78 1.86e-02 GO:0012505 endomembrane system
3.46 1.12e-02 GO:0005886 plasma membrane
3.41 1.24e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
351.44 1.19e-04 GO:0032395 MHC class II receptor activity
9.84 3.61e-04 GO:0004888 transmembrane receptor activity
6.82 2.17e-03 GO:0004872 receptor activity
5.32 7.26e-03 GO:0004871 signal transducer activity
5.32 7.26e-03 GO:0060089 molecular transducer activity